Navitoclax is named as a drug or biological intervention in 2 clinical trials in our UK, USA and China trial registers, none of which are currently recruiting. The lead sponsor is AbbVie. Registered phases: Phase 1 and Phase 3. Conditions studied include Myeloproliferative Neoplasm; Myelofibrosis (MF).
| NCT ID | Study | Phase | Status |
|---|---|---|---|
| NCT04468984 | Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet Versus Best Available Therapy to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis (ClinicalTrials.gov ↗) Myelofibrosis (MF) |
Phase 3 | Active, closed |
| NCT04041050 | A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm Myeloproliferative Neoplasm |
Phase 1 | Active, closed |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Condition (as registered) | Trials |
|---|---|
| Myeloproliferative Neoplasm | 1 |
| Myelofibrosis (MF) | 1 |
| Lead sponsor | Trials |
|---|---|
| AbbVie | 2 |
| Register | Navitoclax trials |
|---|---|
| Clinical trials in UK | 2 |
| Clinical trials in USA | 2 |
| Clinical trials in China | 2 |
A trial with sites in more than one country appears in each of those registers.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Navitoclax works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Navitoclax (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.