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Priya Life Science Compound trial record
Compound · clinical trials

) Berahyaluronidase alfa clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 7 trials in our USA, Poland, Turkey, Japan, UK, Spain, South Korea, Australia, China, Germany, France, Mexico, Italy, Netherlands, Belgium, Switzerland, Austria, Canada, Brazil, Taiwan, Israel, Ireland, Sweden, Denmark, Czechia, Norway, Portugal and Singapore registers that name ) Berahyaluronidase alfa as an intervention. Synced 10 Nov 2026
7Current trials
3Recruiting now
2Lead sponsors
28Country registers
At a glance

) Berahyaluronidase alfa is named as an intervention in 7 current clinical trials in our USA, Poland, Turkey, Japan, UK, Spain, South Korea, Australia, China, Germany, France, Mexico, Italy, Netherlands, Belgium, Switzerland, Austria, Canada, Brazil, Taiwan, Israel, Ireland, Sweden, Denmark, Czechia, Norway, Portugal and Singapore registers. 3 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is Merck Sharp & Dohme LLC (6). The most-studied condition is Non-Small Cell Lung Cancer.

Patient leaflets for ) Berahyaluronidase alfa

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting343%
  • Active, closed457%

Trials by phase

  • Phase 3457%
  • Phase 2343%
01

Clinical trials of ) Berahyaluronidase alfa

7 trials
StudyPhaseStatusLead sponsorRegisters
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
NCT03486873 · Solid Tumors, Hematologic Malignancies
Phase 3 Recruiting Merck Sharp & Dohme LLC Ireland, UK, USA, China, Germany, France, Spain, Italy, Netherlands, Belgium, Sweden, Denmark, Poland, Switzerland, Austria, Czechia, Norway, Portugal, Turkey, Canada, Brazil, Mexico, Japan, South Korea, Taiwan, Singapore, Australia, Israel
A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)
NCT07190248 · Non-small Cell Lung Cancer
Phase 3 Recruiting Merck Sharp & Dohme LLC UK, USA, China, France, Spain, Italy, Netherlands, Belgium, Poland, Switzerland, Austria, Turkey, Canada, Brazil, Mexico, Japan, South Korea, Taiwan, Australia, Israel
Zanzalintinib Alone or in Combination With Pembrolizumab and Berahyaluronidase Alfa in Participants With Colorectal Cancer With Molecular Residual Disease
NCT07750158 · Colorectal Cancer
Phase 3 Recruiting Exelixis USA
A Clinical Study of Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) to Treat Newly-diagnosed Metastatic Non-small Cell Lung Cancer (MK-3475A-F84)
NCT06698042 · Lung Cancer, Non-Small Cell Lung Cancer
Phase 3 Active, closed Merck Sharp & Dohme LLC UK, USA, China, Germany, Spain, Poland, Turkey, Japan, South Korea
A Study of Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) (Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180)) in Japanese Participants With Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma (R/M cSCC) or Locally Advanced (LA) Unresectable cSCC (MK-3475A-E39)
NCT06041802 · ClinicalTrials.gov ↗ · Squamous Cell Carcinoma
Phase 2 Active, closed Merck Sharp & Dohme LLC Japan
A Study of Participant Reported Preference for Subcutaneous Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) Over Intravenous Pembrolizumab (MK-3475) Formulation in Multiple Tumor Types (MK-3475A-F11)
NCT06099782 · Non-Small Cell Lung Cancer, Renal Cell Carcinoma, Melanoma
Phase 2 Active, closed Merck Sharp & Dohme LLC USA, France, Poland, Turkey, Japan, Australia
A Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) Coformulated With Berahyaluronidase Alfa (MK-3475A) in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL)(MK-3475A-F65)
NCT06504394 · Classical Hodgkin Lymphoma Recurrent, Classical Hodgkin Lymphoma Refractory, Primary Mediastinal Large B-cell Lymphoma Recurrent
Phase 2 Active, closed Merck Sharp & Dohme LLC UK, USA, Germany, Spain, Poland, Turkey, Mexico, South Korea, Australia

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with ) Berahyaluronidase alfa

13 conditions
Non-Small Cell Lung Cancer2Solid Tumors1Hematologic Malignancies1Lung Cancer1Non-small Cell Lung Cancer1Classical Hodgkin Lymphoma Recurrent1Classical Hodgkin Lymphoma Refractory1Primary Mediastinal Large B-cell Lymphoma Recurrent1Primary Mediastinal Large B-cell Lymphoma Refractory1Renal Cell Carcinoma1Melanoma1Colorectal Cancer1
All 13 conditions
Condition (as registered)Trials
Non-Small Cell Lung Cancer2
Solid Tumors1
Hematologic Malignancies1
Lung Cancer1
Non-small Cell Lung Cancer1
Classical Hodgkin Lymphoma Recurrent1
Classical Hodgkin Lymphoma Refractory1
Primary Mediastinal Large B-cell Lymphoma Recurrent1
Primary Mediastinal Large B-cell Lymphoma Refractory1
Renal Cell Carcinoma1
Melanoma1
Colorectal Cancer1
Squamous Cell Carcinoma1
05

Related compounds

06

Questions about ) Berahyaluronidase alfa trials

How many clinical trials are testing ) Berahyaluronidase alfa?

7 current trials in our USA, Poland, Turkey, Japan, UK, Spain, South Korea, Australia, China, Germany, France, Mexico, Italy, Netherlands, Belgium, Switzerland, Austria, Canada, Brazil, Taiwan, Israel, Ireland, Sweden, Denmark, Czechia, Norway, Portugal and Singapore registers name ) Berahyaluronidase alfa as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.

Are ) Berahyaluronidase alfa trials recruiting patients?

Yes. 3 of the 7 trials are recruiting: 3 with sites in USA, 2 with sites in Poland, 2 with sites in Turkey, 2 with sites in Japan, 2 with sites in UK, 2 with sites in Spain, 2 with sites in South Korea, 2 with sites in Australia, 2 with sites in China, 1 with sites in Germany, 2 with sites in France, 2 with sites in Mexico, 2 with sites in Italy, 2 with sites in Netherlands, 2 with sites in Belgium, 2 with sites in Switzerland, 2 with sites in Austria, 2 with sites in Canada, 2 with sites in Brazil, 2 with sites in Taiwan, 2 with sites in Israel, 1 with sites in Ireland, 1 with sites in Sweden, 1 with sites in Denmark, 1 with sites in Czechia, 1 with sites in Norway, 1 with sites in Portugal and 1 with sites in Singapore. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors ) Berahyaluronidase alfa clinical trials?

Merck Sharp & Dohme LLC (6) and Exelixis (1). The number in brackets is how many trials each organisation leads.

Are there ) Berahyaluronidase alfa clinical trials in Ireland?

Yes. 1 trial in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how ) Berahyaluronidase alfa works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how ) Berahyaluronidase alfa works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists ) Berahyaluronidase alfa (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.