🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Writer Login
Latest
Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma ◆ Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide ◆ The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany ◆ Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact ◆ The Pharmacist's Role: How Community Pharmacies in Ireland and the UK Are Adapting as Patients Bypass High-Street Stores for Direct Delivery ◆ GLP-1 Therapeutics and Clinical Research Updates: Brain Reward Mapping, Oral Small Molecules, and Triple-Agonist Horizons ◆ Rinn Pharma & Biopharma Joins NordicPharmaTrain Network to Accelerate European Research & Advanced Manufacturing ◆ Markets Surge as August Opens: $400B Big Pharma Merger Speculation & AstraZeneca Deal Talks Grab Global Headlines ◆ Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma ◆ Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide ◆ The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany ◆ Ireland's €93.8 Billion Non-EU Pharma Export Engine: Trade Data, Destination Markets, and Economic Impact ◆ The Pharmacist's Role: How Community Pharmacies in Ireland and the UK Are Adapting as Patients Bypass High-Street Stores for Direct Delivery ◆ GLP-1 Therapeutics and Clinical Research Updates: Brain Reward Mapping, Oral Small Molecules, and Triple-Agonist Horizons ◆ Rinn Pharma & Biopharma Joins NordicPharmaTrain Network to Accelerate European Research & Advanced Manufacturing ◆ Markets Surge as August Opens: $400B Big Pharma Merger Speculation & AstraZeneca Deal Talks Grab Global Headlines ◆
Updated 27 Aug 2026 · ClinicalTrials.gov

Clinical Trials in Manchester

← All UK trials

The most recently updated industry-sponsored clinical trials recruiting across the United Kingdom — searchable by condition, sponsor, phase and city. Refreshed daily from the ClinicalTrials.gov registry.

28
Recruiting now
41
Studies tracked
Manchester
Selected city
Active Phase 1/Phase 2
Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancer
Metastatic Prostate Cancer
AstraZeneca · started 2022-06-02
📍 Cambridge · Glasgow · Manchester · Plymouth
NCT05367440 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Proteinuric Kidney Disease
Vertex Pharmaceuticals Incorporated · started 2022-03-30
📍 Basildon · Bellshill · Birmingham · Carshalton · Leicester
NCT05312879 on ClinicalTrials.gov ↗
Active Phase 2
HM15136 (Efpegerglucagon) Treatment for 8 Weeks in Subjects Aged ≥2 Years With Congenital Hyperinsulinism (CHI)
Congenital Hyperinsulinism
Hanmi Pharmaceutical Company Limited · started 2022-05-05
📍 London · Manchester
NCT04732416 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation
Advanced Solid Tumors Harboring KRAS G12C Mutation
Bayer · started 2024-11-08
📍 Manchester · Sutton
NCT06659341 on ClinicalTrials.gov ↗
Active Phase 2
Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Synovial Sarcoma, Myxoid Liposarcoma
USWM CT, LLC · started 2019-08-13
📍 London · Manchester
NCT04044768 on ClinicalTrials.gov ↗
Active Phase 3
Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1)
Biliary Tract Neoplasms
AstraZeneca · started 2019-04-16
📍 Bristol · Cambridge · London · Manchester · Oxford
NCT03875235 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer
Advanced Lung Cancer
BioNTech SE · started 2025-05-02
📍 Bristol · Leeds · Liverpool · London · Manchester
NCT06892548 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)
Chronic Inducible Urticaria, Cold Urticaria, Cold-Induced Urticaria, Symptomatic Dermographism
Celldex Therapeutics · started 2026-01-15
📍 Cambridge · Glasgow · Manchester
NCT07266402 on ClinicalTrials.gov ↗
Active Phase 3
Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer With or Without Actionable Genomic Alterations (TROPION-LUNG01)
Non-small Cell Lung Cancer
Daiichi Sankyo · started 2020-12-21
📍 London · Manchester · Middlesbrough
NCT04656652 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Assess Zipalertinib Versus Placebo in Participants With Early Stage NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection
Lung Cancer, Adjuvant, Post-surgical, EGFR
Taiho Oncology, Inc. · started 2025-12-22
📍 Manchester · Nottingham · Torquay · Cardiff
NCT07128199 on ClinicalTrials.gov ↗
By invitation Phase 2
Open-Label, Long-Term, Extension Study of Infigratinib in Children With Hypochondroplasia
Hypochondroplasia
QED Therapeutics, a BridgeBio company · started 2026-04-23
📍 Manchester · Sheffield · Glasgow
NCT07393373 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
Pancreatic Cancer, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Ductal Adenocarcinoma (PDAC)
Revolution Medicines, Inc. · started 2025-12-15
📍 Birmingham · Glasgow · London · Manchester
NCT07252232 on ClinicalTrials.gov ↗
Recruiting Phase 3
Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
Non-small Cell Lung Cancer, Anaplastic Lymphoma Kinase-positive
Nuvalent Inc. · started 2025-07-17
📍 Cambridge · Guildford · Hampstead · London · Maidstone
NCT06765109 on ClinicalTrials.gov ↗
Recruiting Phase 3
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Solid Tumors, Hematologic Malignancies
Merck Sharp & Dohme LLC · started 2018-08-21
📍 Aberdeen · Cambridge · Edinburgh · Manchester · Sheffield
NCT03486873 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Metastatic Castration-resistant Prostatic Neoplasms
Janssen Research & Development, LLC · started 2025-09-02
📍 Birmingham · London · Manchester · Sutton
NCT07164443 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
AbbVie · started 2025-04-24
📍 London · Oxford · Sutton · Manchester
NCT06820463 on ClinicalTrials.gov ↗
Active Phase 2
Basket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)
Breast Cancer, Cholangiocarcinoma, Colorectal Cancer, Head and Neck Neoplasms
Hoffmann-La Roche · started 2015-11-19
📍 Cambridge · London · Manchester
NCT02568267 on ClinicalTrials.gov ↗
Active Phase 1
Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors
Neoplasms
Tesaro, Inc. · started 2016-03-07
📍 Newcastle upon Tyne · Aberdeen · London · Manchester · Oxford
NCT02715284 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Trial Evaluating Brelovitug (BJT-778) vs Bulevirtide for the Treatment of Chronic Hepatitis Delta Infection (AZURE-2)
Chronic Hepatitis D Infection
Mirum Pharmaceuticals, Inc. · started 2025-08-27
📍 Birmingham · London · Manchester · Cottingham
NCT07200908 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer
Mirati Therapeutics Inc. · started 2020-12-02
📍 Birmingham · Edinburgh · Kent · Leicester · London
NCT04613596 on ClinicalTrials.gov ↗
Active Phase 3
A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab
Unresectable Hepatocellular Carcinoma
Hoffmann-La Roche · started 2021-04-26
📍 Birmingham · Liverpool · London · Manchester · Newcastle upon Tyne
NCT04770896 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors
Solid Tumor
Genentech, Inc. · started 2024-11-14
📍 Edinburgh · London · Manchester · Sutton
NCT06619587 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)
Chronic Graft-versus-host-disease
Incyte Corporation · started 2026-05-20
📍 Birmingham · Cambridge · Glasgow · Leeds · London
NCT07124078 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide
Chronic Hepatitis D
Mirum Pharmaceuticals, Inc. · started 2026-02-26
📍 Cottingham · Cardiff · London · Manchester
NCT07454837 on ClinicalTrials.gov ↗
Active Phase 2
Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer
Hepatocellular Carcinoma, Biliary Tract Cancer
AstraZeneca · started 2023-04-24
📍 Cambridge · London · Manchester
NCT05775159 on ClinicalTrials.gov ↗
Active
PASS of Paediatric Patients Initiating Selumetinib
Neurofibromatosis Type 1
AstraZeneca · started 2022-05-23
📍 London · Manchester · Newcastle upon Tyne
NCT05388370 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
Malignant Neoplasm
Merck Sharp & Dohme LLC · started 2025-08-11
📍 East Sussex · Truro · London · Edinburgh · Birmingham
NCT06979596 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
Carcinoma, Non-Small-Cell Lung
Eli Lilly and Company · started 2025-03-27
📍 Birmingham · East Sussex · Huddersfield · London · Manchester
NCT06890598 on ClinicalTrials.gov ↗
Recruiting Phase 3
BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies
Healthy
Pfizer · started 2025-08-25
📍 Bristol · London · Truro · Southampton · Manchester
NCT07160244 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)
Breast Neoplasms
Merck Sharp & Dohme LLC · started 2025-07-21
📍 London · Leicester · Manchester
NCT07060807 on ClinicalTrials.gov ↗
Recruiting
BoStOn SCientific Rhythm MAnagemenT REgiStry
Cardiac Disease
Boston Scientific Corporation · started 2021-03-31
📍 London · Manchester
NCT04823663 on ClinicalTrials.gov ↗
Recruiting Phase 3
Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)
Von Hippel-Lindau Disease, Malignant Neoplasms
Merck Sharp & Dohme LLC · started 2026-03-23
📍 Glasgow · London · Manchester
NCT07405164 on ClinicalTrials.gov ↗
Recruiting Phase 2
Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)
Lupus Nephritis
Autolus Limited · started 2026-01-16
📍 Birmingham · Bristol · Cambridge · Edinburgh · Glasgow
NCT07053800 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
Metastatic Solid Tumor, Recurrent Solid Tumor, Advanced Solid Tumor, Urinary Bladder Neoplasm
Eli Lilly and Company · started 2024-07-01
📍 London · Manchester
NCT06465069 on ClinicalTrials.gov ↗
Recruiting Phase 3
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
Non-Small Cell Lung Cancer
Summit Therapeutics · started 2023-10-26
📍 Leeds · London · Manchester
NCT05899608 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease
Crohn's Disease
Eli Lilly and Company · started 2024-03-13
📍 Edinburgh · Headington · London · Manchester · Sheffield
NCT05509777 on ClinicalTrials.gov ↗
Active Phase 3
A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)
Breast Cancer
AstraZeneca · started 2021-10-18
📍 Blackpool · Bristol · Cardiff · Colchester · Edinburgh
NCT05104866 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments
Multiple Myeloma
Pfizer · started 2021-10-04
📍 Bournemouth · Oxford · Cardiff · Bristol · Canterbury
NCT05020236 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
Prostate Cancer Metastatic
Merck Sharp & Dohme LLC · started 2023-12-31
📍 Cambridge · Truro · Glasgow · London · Manchester
NCT06136624 on ClinicalTrials.gov ↗
Recruiting Phase 4
A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation
Chronic Obstructive Pulmonary Disease, Hyperinflation
AstraZeneca · started 2025-11-24
📍 Harefield · London · Manchester
NCT07073950 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis
Eli Lilly and Company · started 2023-12-21
📍 Aberdeen · Dundee · Huddersfield · Leeds · Manchester
NCT06119581 on ClinicalTrials.gov ↗
No trials match your search.

Browse by city

London · 115 Manchester · 41 Cambridge · 34 Birmingham · 30 Glasgow · 25 Oxford · 24 Edinburgh · 20 Sheffield · 20 Leicester · 17 Newcastle upon Tyne · 15 Bristol · 15 Liverpool · 14 Leeds · 13 Southampton · 13 Cardiff · 12 Sutton · 11

Browse by condition

Chronic Lymphocytic Leukemia · 4 Colitis, Ulcerative · 3 Non-small Cell Lung Cancer · 3 Carcinoma, Non-Small-Cell Lung · 3 Breast Cancer · 3 Crohn's Disease · 3 Rheumatoid Arthritis · 2 Hypertension · 2 Alzheimer Disease · 2 Age-Related Macular Degeneration · 2 Prostatic Neoplasms · 2 Type 1 Diabetes · 2 Major Depressive Disorder (MDD) · 2 Idiopathic Pulmonary Fibrosis · 2 Chronic Inflammatory Demyelinatin… · 2 Amyotrophic Lateral Sclerosis · 2
Cite this page

Priya Life Science (2026). Clinical Trials in the UK Tracker. Available at: https://priyalifescience.com/clinical-trials-uk/city/manchester (Accessed: 27 August 2026).

Embed this data ↗

Source: ClinicalTrials.gov, U.S. National Library of Medicine — industry-sponsored studies in a recruiting status with at least one UK site, most recently updated first, refreshed daily. This is a curated slice of the registry, not every UK trial; UK studies may also be registered on ISRCTN. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. Compare pay for the teams running these studies in our UK Pharma Salary Guide, or see our Ireland, EU and USA trackers.