Lunsekimig: * Pharmaceutical form: solution for injection * Route of administration: subcutaneous
Mometasone furoate nasal spray (MFNS): * Pharmaceutical form: Solution for administration via spray pump * Route of administration: intranasal spray
This is a single-arm extension study to investigate the long-term safety, tolerability, and efficacy of lunsekimig in adult participants with inadequately controlled CRSwNP who have completed a previous lunsekimig CRSwNP clinical study (also referred to as the parent study ACT18207).
The study duration will be up to approximately 148 weeks per participant, including 144 weeks of treatment period and 4 weeks of follow-up.
| Facility | City | Region | Status |
|---|---|---|---|
| Modena Allergy + Asthma- Site Number : 8400005 | La Jolla | California | |
| Sacramento Ear Nose & Throat - Roseville- Site Number : 8400003 | Roseville | California | |
| Treasure Valley Medical Research- Site Number : 8400002 | Boise | Idaho | |
| Essential Medical Research- Site Number : 8400020 | Tulsa | Oklahoma | |
| McGovern Medical School - UT Physicians Dermatology - Bellaire Station- Site Number : 8400017 | Bellaire | Texas | |
| Pharmaceutical Research & Consulting- Site Number : 8400004 | Dallas | Texas | |
| ENT Associates of Texas - McKinne- Site Number : 8400014 | McKinney | Texas | |
| Alamo ENT Associates- Site Number : 8400001 | San Antonio | Texas | |
| Eastern Virginia Medical School (EVMS) Medical Group- Site Number : 8400008 | Norfolk | Virginia | |
| Investigational Site Number : 0320002 | Rosario | Santa Fe Province | |
| Investigational Site Number : 0320001 | Buenos Aires | Argentina | |
| Investigational Site Number : 0320003 | Mendoza | Argentina | |
| Investigational Site Number : 0560002 | Ghent | Belgium | |
| Investigational Site Number : 0560001 | Leuven | Belgium | |
| Investigational Site Number : 1000001 | Sofia | Bulgaria | |
| Investigational Site Number : 6160004 | Poznan | Greater Poland Voivodeship | |
| Investigational Site Number : 6160002 | Krakow | Lesser Poland Voivodeship | |
| Investigational Site Number : 6160007 | Wroclaw | Lower Silesian Voivodeship | |
| Investigational Site Number : 6160001 | Warsaw | Masovian Voivodeship | |
| Investigational Site Number : 6160005 | Warsaw | Masovian Voivodeship | |
| Investigational Site Number : 6160003 | Katowice | Silesian Voivodeship | |
| Investigational Site Number : 8260004 | Gloucester | Gloucestershire | |
| Investigational Site Number : 8260003 | Manchester | United Kingdom | |
| Investigational Site Number : 8260001 | Newcastle upon Tyne | United Kingdom |
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06914908 on ClinicalTrials.gov ↗ ← All trials in the UK