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Compound · clinical trials

Furmonertinib clinical trials

Also listed in trial records as AST2818
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 20 trials in our China, UK and USA registers that name Furmonertinib as an intervention. Synced 25 Sep 2026
20Current trials
14Recruiting now
15Lead sponsors
3Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Furmonertinib is named as an intervention in 20 current clinical trials in our China, UK and USA registers. 14 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is ArriVent BioPharma, Inc (2). The most-studied condition is Non-small Cell Lung Cancer.

Trials by status

  • Recruiting1470%
  • Not yet open210%
  • Active, closed420%

Trials by phase

  • Phase 21260%
  • Phase 1/2420%
  • Phase 3210%
  • Phase 115%
  • Not applicable15%
01

Clinical trials of Furmonertinib

20 trials
StudyPhaseStatusLead sponsorRegisters
To Assess the Efficacy and Safety of Furmonertinib Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage II-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy
NCT04853342 · ClinicalTrials.gov ↗ · Non-small Cell Lung Carcinoma
Phase 3 Recruiting Allist Pharmaceuticals, Inc. China
Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation
NCT04322890 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer, EGFR Gene Mutation, ALK Gene Mutation
Phase 2 Recruiting Hunan Province Tumor Hospital China
Furmonertinib Monotherapy and Combination Therapy in Advanced EGFR Mutant NSCLC With Uncleared ctDNA
NCT05334277 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
Phase 2 Recruiting Sun Yat-sen University China
High-dose Furmonertinib for First-line Treatment of EGFR Mutated NSCLC With Central Nervous System (CNS) Metastases
NCT05379803 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
Phase 2 Recruiting Hunan Province Tumor Hospital China
High-dose Furmonertinib in the Treatment in Patients With Advanced, Metastatic NSCLC With Progressed After First- or Second-line Treatment With Osimertinib
NCT06394674 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
Phase 2 Recruiting Changhai Hospital China
High-dose Furmonertinib or Combined With Chemotherapy in EGFR-mutant Advanced NSCLC After Disease Progression on Third-generation EGFR-TKI
NCT06652048 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
Phase 2 Recruiting Jialei Wang China
A Clinical Trial of Furmonertinib Combined With Anlotinib as First-line Treatment for Advanced NSCLC With EGFR-sensitive Mutations and Brain Metastasis
NCT06945705 · ClinicalTrials.gov ↗ · NSCLC
Phase 2 Recruiting Henan Cancer Hospital China
Furmonertinib Combined With Intrathecal Chemotherapy and Stereotactic Radiotherapy (SRT) for EGFR-Mutated NSCLC Patients With Brain Parenchymal and Leptomeningeal Metastases
NCT07304739 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer
Phase 2 Recruiting Tianjin Medical University Cancer Institute and Hospital China
A Study of SKB571 Combination Therapy in Participants With Non-Small Cell Lung Cancer (NSCLC)
NCT07622186 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer
Phase 2 Recruiting Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. China
IN10018 Combination Therapy in Advanced EGFR Mutation-positive NSCLC
NCT05994131 · ClinicalTrials.gov ↗ · NSCLC
Phase 1/2 Recruiting InxMed (Shanghai) Co., Ltd. China
Phase Ib/II Study of Vebreltinib With Furmonertinib in NSCLC Patients With c-Met Amplification After EGFR-TKI Failure
NCT07087223 · ClinicalTrials.gov ↗ · Non Small Cell Lung Cancer NSCLC
Phase 1/2 Recruiting Peking University Cancer Hospital & Institute China
A Study of MHB036C Combined With Anti-tumor Therapies in Patients With Advanced Lung Cancer
NCT07229599 · ClinicalTrials.gov ↗ · Advanced Lung Cancer
Phase 1/2 Recruiting Minghui Pharmaceutical (Hangzhou) Ltd China
Vebreltinib Plus Furmonertinib in Patients With EGFR-mutated Advanced Non-small Cell Lung Cancer and High PD-L1 Expression
NCT07655622 · ClinicalTrials.gov ↗ · Non-Small-Cell Lung Cancer
Phase 1/2 Recruiting Second Affiliated Hospital of Nanchang University China
Evaluating High-dose Furmonertinib with Bevacizumab and Pemetrexed for EGFRm NSCLC with Leptomeningeal Metastasis
NCT06643000 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer, Leptomeningeal Metastasis, EGFR Gene Mutation
Not applicable Recruiting Henan Cancer Hospital China
Furmonertinib 160mg vs 80mg + Chemotherapy in EGFR-Mutated NSCLC With Brain Metastases: Efficacy and Safety Study
NCT07365410 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer (NSCLC), Brain Metastases, Furmonertinib
Phase 2 Not yet open Tianjin Medical University Cancer Institute and Hospital China
Combining Furmonertinib With Local Therapy for Inoperable Early-stage Lung Cancer: A Phase II Trial
NCT07517640 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
Phase 2 Not yet open Shanghai Pulmonary Hospital, Shanghai, China China
Study to Compare Furmonertinib to Platinum-Based Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations (FURVENT)
NCT05607550 · ClinicalTrials.gov ↗ · Metastatic Non-Small Cell Lung Cancer, Advanced Non-Small Cell Lung Cancer, EGFR Exon 20 Mutations
Phase 3 Active, closed ArriVent BioPharma, Inc. UK, USA, China
Neoadjuvant Furmonertinib and Cisplatin/Pemetrexed as in EGFR Mutated Stage IIA-IIIB Resectable NSCLC (FORESEE)
NCT05430802 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
Phase 2 Active, closed Tang-Du Hospital China
Efficacy and Safety of Furmonertinib in Patients With Locally Advanced or Metastatic NSCLC With EGFR Exon 20 Insertion
NCT05466149 · ClinicalTrials.gov ↗ · NSCLC
Phase 2 Active, closed Allist Pharmaceuticals, Inc. China
Study of Furmonertinib in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Activating, Including Uncommon, Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Mutations
NCT05364073 · ClinicalTrials.gov ↗ · Non-Small Cell Lung Cancer (NSCLC), Metastatic Non-Small Cell Lung Cancer, Advanced Non-Small Cell Lung Cancer
Phase 1 Active, closed ArriVent BioPharma, Inc. UK, USA, China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Furmonertinib

21 conditions
All 21 conditions
Condition (as registered)Trials
Non-small Cell Lung Cancer4
Non-Small Cell Lung Cancer4
NSCLC3
Metastatic Non-Small Cell Lung Cancer2
Advanced Non-Small Cell Lung Cancer2
EGFR Gene Mutation2
Non Small Cell Lung Cancer2
Non-Small Cell Lung Cancer (NSCLC)1
HER2 Exon 20 Mutations1
EGFR Exon 20 Mutations1
Leptomeningeal Metastasis1
Non-small Cell Lung Cancer (NSCLC)1
Brain Metastases1
Furmonertinib1
EGFR Mutation1
Advanced Lung Cancer1
Non-Small-Cell Lung Cancer1
Non-small Cell Lung Carcinoma1
ALK Gene Mutation1
ROS1 Gene Mutation1
Non Small Cell Lung Cancer NSCLC1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
ArriVent BioPharma, Inc.2
Henan Cancer Hospital2
Allist Pharmaceuticals, Inc.2
Hunan Province Tumor Hospital2
Tianjin Medical University Cancer Institute and Hospital2
Tang-Du Hospital1
Shanghai Pulmonary Hospital, Shanghai, China1
InxMed (Shanghai) Co., Ltd.1
Minghui Pharmaceutical (Hangzhou) Ltd1
Changhai Hospital1
Second Affiliated Hospital of Nanchang University1
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.1
Jialei Wang1
Sun Yat-sen University1
Peking University Cancer Hospital & Institute1
04

By country register

RegisterTrialsRecruiting
Clinical trials in China2014
Clinical trials in UK20
Clinical trials in USA20

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Furmonertinib trials

How many clinical trials are testing Furmonertinib?

20 current trials in our China, UK and USA registers name Furmonertinib (also registered as AST2818) as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Furmonertinib trials recruiting patients?

Yes. 14 of the 20 trials are recruiting: 14 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Furmonertinib clinical trials?

ArriVent BioPharma, Inc (2), Henan Cancer Hospital (2), Allist Pharmaceuticals, Inc (2) and Hunan Province Tumor Hospital (2), among 15 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Furmonertinib works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Furmonertinib works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Furmonertinib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.