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Compound · clinical trials

Nimotuzumab

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 24 trials in our China register that name Nimotuzumab as an intervention. Synced 24 Sep 2026
24Trials tracked
15Recruiting now
14Lead sponsors
1Country register
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

Nimotuzumab is named as a drug or biological intervention in 24 clinical trials in our China trial register, 15 of which are recruiting. Lead sponsors include Cancer Institute and Hospital, Chinese Academy of Medical Sciences (4), Zhejiang University (3) and Fudan University (3). Registered phases: Phase 2, Phase 3, Phase 1/2, Phase 2/3 and Not applicable. Conditions studied include Head & Neck Cancer; Nasopharyngeal Carcinoma; Pancreatic Cancer.

01

Clinical trials of Nimotuzumab

24 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT04821778 Chemoradiotherapy in Esophageal or Esophagogastric Junction Cancer (ClinicalTrials.gov ↗)
Esophagus Cancer, Esophagogastric Junction Cancer, Chemoradiation
Phase 3 Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences China
NCT04821843 Neoadjuvant Treatment Modalities in Esophageal Cancer (ClinicalTrials.gov ↗)
Esophageal Cancer, Chemotherapy Effect, Chemoradiation
Phase 3 Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences China
NCT05772208 Intensified Treatments for Patients With Locally Advanced Nasopharyngeal Carcinoma With Detectable EBV DNA After One Cycle GP Regime Neoadjuvant Chemotherapy (ClinicalTrials.gov ↗)
Nasopharyngeal Carcinoma
Phase 3 Recruiting Fudan University China
NCT07333274 Compare Radiotherapy Plus Nimotuzumab Versus Radiotherapy Alone in Platinum-ineligible Patients With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (ClinicalTrials.gov ↗)
Head & Neck Squamous Cell Carcinoma, Head & Neck Cancer
Phase 3 Recruiting Shandong Cancer Hospital and Institute China
NCT07445048 Postoperative Radiotherapy Combined With Nimotuzumab Followed by Benmelstobart in High-Risk Patients With Head and Neck Squamous Cell Carcinoma (ClinicalTrials.gov ↗)
Head & Neck Squamous Cell Carcinoma, Head & Neck Cancer, Postoperative Adjuvant Treatment
Phase 3 Recruiting Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University China
NCT06509009 Nimotuzumab Combined With TGP as First-line Therapy in Patients With Recurrent/Metastatic Nasopharyngeal Carcinoma (ClinicalTrials.gov ↗)
Nasopharyngeal Carcinoma by AJCC V8 Stage
Phase 2 Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences China
NCT06718205 Nimotuzumab Combined With Sintilimab and Chemotherapy for Advanced Esophageal Squamous Cell Carcinoma (ClinicalTrials.gov ↗)
Esophageal Cancer
Phase 2 Recruiting The First Affiliated Hospital of Zhengzhou University China
NCT06770452 HRS-4642 With Nimotuzumab and Chemotherapy for First-line Treatment of Advanced Pancreatic Cancer Patients
Metastatic Pancreatic Carcinoma
Phase 2 Recruiting Zhejiang University China
NCT06912711 TN Induction and Adjuvant Therapy for Resectable Local Recurrent Nasopharyngeal Carcinoma (ClinicalTrials.gov ↗)
Nasopharyngeal Carcinoma
Phase 2 Recruiting Sun Yat-sen University China
NCT07240766 HRS-4642 in Combination With Nimotuzumab and Chemotherapy for BRPC With KRAS G12D Mutation (ClinicalTrials.gov ↗)
Borderline Resectable Pancreatic Adenocarcinoma
Phase 2 Recruiting Zhejiang University China
NCT07353723 Nimotuzumab Combined With Toripalimab and Chemotherapy for Locally Advanced Tonsillar Cancer (ClinicalTrials.gov ↗)
Head & Neck Cancer
Phase 2 Recruiting Tang-Du Hospital China
NCT07457528 Efficacy and Safety of Neo-CRT Plus Serplulimab, Nimotuzumab in Patients With Locally Advanced Resectable ESCC (ClinicalTrials.gov ↗)
Resectable Esophageal Squamous Cell Carcinoma
Phase 2 Recruiting Tianjin Medical University Cancer Institute and Hospital China
NCT07601737 Nimotuzumab Combined With Immunotherapy and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma (ClinicalTrials.gov ↗)
Head and Neck Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma (HNSCC), Head & Neck Cancer
Phase 2 Recruiting Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine China
NCT07105592 A Study of Nimotuzumab Plus Adebrelimab With Chemotherapy in Cisplatin-Ineligible Patients With Head And Neck Squamous Cell Carcinoma (ClinicalTrials.gov ↗)
Head and Neck Squamous Cell Carcinoma
Phase 1/2 Recruiting Fudan University China
NCT05717790 Concurrent and Adjuvant Nimotuzumab Combined With Induction Chemotherapy Plus Chemoradiation in Nasopharyngeal Carcinoma (ClinicalTrials.gov ↗)
Nasopharyngeal Carcinoma by AJCC V8 Stage
Not applicable Recruiting Fourth Affiliated Hospital of Guangxi Medical University China
NCT06409429 Nimotuzumab Combined With GX as Postoperative Adjuvant Therapy in Pancreatic Cancer (ClinicalTrials.gov ↗)
Pancreatic Cancer
Phase 2/3 Not yet open Tianjin Medical University Cancer Institute and Hospital China
NCT05316480 Nimotuzumab in EGFR Highly Expressed Pancreatic Neuroendocrine Neoplasms (ClinicalTrials.gov ↗)
Pancreatic Neuroendocrine Neoplasm
Phase 2 Not yet open Fudan University China
NCT07277452 Nimotuzumab Combined With Nab-paclitaxel/Gemcitabine in the Perioperative Treatment of High-risk Resectable/Borderline Resectable Pancreatic Cancer (ClinicalTrials.gov ↗)
Pancreatic Cancer, Adult
Phase 2 Not yet open The First Affiliated Hospital with Nanjing Medical University China
NCT07821242 Nimotuzumab Plus Radiotherapy in Elderly Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma (ClinicalTrials.gov ↗)
Head & Neck Cancer, Radiotherapy
Phase 2 Not yet open Ke Hu China
NCT07736612 A Pan-RAS Inhibitor in Combination With Anti-Tumor Therapy in Participants With Advanced Pancreatic Cancer (ClinicalTrials.gov ↗)
Pancreatic Cancer, RAS Mutations or Amplifications
Phase 1/2 Not yet open Zhejiang University China
NCT07312578 Nimotuzumab,Camrelizumab, and Neoadjuvant Chemotherapy๏ผˆnCT๏ผ‰ in the Treatment of Esophageal Squamous Cell Carcinoma (ClinicalTrials.gov ↗)
Esophageal Squamous Cell Carcinoma
Phase 2 By invitation Peking University China
NCT04456322 Radiotherapy Plus Nimotuzumab or Cisplatin in Nasopharyngeal Carcinoma (ClinicalTrials.gov ↗)
Nasopharyngeal Carcinoma
Phase 3 Active, closed Sun Yat-sen University China
NCT04223024 Concurrent Chemoradiotherapy With Nimotuzumab for High Risk Nasopharyngeal Carcinoma (ClinicalTrials.gov ↗)
Nasopharyngeal Carcinoma
Phase 2 Active, closed Sun Yat-sen University China
NCT06771596 Nimotuzumab High-risk, Locally Advanced Squamous Cell Carcinoma of the Cervix (ClinicalTrials.gov ↗)
Uterine Cervical Neoplasms
Phase 2 Active, closed Cancer Institute and Hospital, Chinese Academy of Medical Sciences China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

25 conditions
Condition (as registered)Trials
Head & Neck Cancer5
Nasopharyngeal Carcinoma4
Pancreatic Cancer2
Head and Neck Squamous Cell Carcinoma2
Nasopharyngeal Carcinoma by AJCC V8 Stage2
Esophageal Cancer2
Head & Neck Squamous Cell Carcinoma2
Chemoradiation2
Metastatic Pancreatic Carcinoma1
Uterine Cervical Neoplasms1
Radiotherapy1
Pancreatic Neuroendocrine Neoplasm1
RAS Mutations or Amplifications1
Head and Neck Squamous Cell Carcinoma (HNSCC)1
Neoadjuvant Therapy1
Borderline Resectable Pancreatic Adenocarcinoma1
Esophageal Squamous Cell Carcinoma1
Esophagus Cancer1
Esophagogastric Junction Cancer1
Targeted Therapy1
Pancreatic Cancer, Adult1
Postoperative Adjuvant Treatment1
Resectable Esophageal Squamous Cell Carcinoma1
Chemotherapy Effect1
Surgery1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Cancer Institute and Hospital, Chinese Academy of Medical Sciences4
Zhejiang University3
Fudan University3
Sun Yat-sen University3
Tianjin Medical University Cancer Institute and Hospital2
Ke Hu1
Tang-Du Hospital1
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine1
Fourth Affiliated Hospital of Guangxi Medical University1
The First Affiliated Hospital of Zhengzhou University1
Shandong Cancer Hospital and Institute1
Peking University1
The First Affiliated Hospital with Nanjing Medical University1
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University1
04

Trials by country register

RegisterNimotuzumab trials
Clinical trials in China24

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Nimotuzumab works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Nimotuzumab (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.