Vancomycin clinical trials
Vancomycin is named as an intervention in 21 current clinical trials in our Canada, France, Australia, Spain, Italy, Germany, Netherlands, Sweden, Israel, Switzerland, Egypt, UK, China, Japan and Singapore registers. 14 are recruiting patients now. The most common phase is Phase 4. The sponsor with the most trials is Microbiotica Ltd (1). The most-studied condition is Staphylococcus Aureus Bacteremia. The EU clinical trials register (CTIS) separately lists 5 authorised or ongoing trials.
Where Vancomycin is approved
All regulators →Of the three regulators tracked here, the first to approve Vancomycin was the US, on 29 Apr 1993. It is approved in 2 of the 3 regulators tracked here.
From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.
Vancomycin patents and exclusivity
Expiry tracker →Protections still running for marketed products containing Vancomycin, as listed by the regulators. Expired patents and exclusivities, and discontinued products, are not shown.
- 13 listed patents; the last listed expires 6 Nov 2035 (US 10188697).
Reproduced from the FDA Orange Book and Purple Book (checked 8 Nov 2026) and the European Commission's Union Register of medicinal products (CC BY 4.0; the EU expiry date is calculated exactly as the Commission's register displays it). Listed patents and dates are as submitted to or published by the regulator and may not reflect litigation, invalidation, settlements, lapsed fees or later extensions. This is not legal advice or a freedom-to-operate opinion, and it does not say when a generic or biosimilar will launch.
What health systems spend on Vancomycin
All medicines →From NHSBSA Prescription Cost Analysis (Open Government Licence v3.0) and CMS State Drug Utilization Data. Both are gross amounts: neither system publishes its discounts or rebates per drug. Products combining several substances are not counted here.
How Vancomycin works
All drug targets →- FeverPhase 3
- Hodgkins lymphomaPhase 3
- Bacterial arthritisPhase 3
- Bacterial infectious disease with sepsisPhase 3
- Clostridium difficile infectionPhase 3
- InfectionPhase 3
- LeukemiaPhase 3
- LymphomaPhase 3
- Methicillin-resistant staphylococcus aureus infectious diseasePhase 3
- NeutropeniaPhase 3
Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL262777, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 10932, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.
Patient leaflets for Vancomycin
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- IEIreland: 15 products on the HPRA listEach product record links to the HPRA, which publishes the leaflet and SmPC.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Reference identifiers for Vancomycin
- ChEMBL
- CHEMBL262777
- DrugBank
- DB00512
- PubChem CID
- 14969
- CAS number
- 1404-90-6
- FDA UNII
- 6Q205EH1VU
- Wikidata
- Q424027
- Wikipedia
- Vancomycin
Codes that identify this medicine in other databases, from Wikidata (CC0), matched by its ChEMBL ID. The ATC code is the WHO classification of what the medicine is used for.
Trials by status
Trials by phase
Clinical trials of Vancomycin
21 trialsRegisters list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Vancomycin in the EU trials register (CTIS)
5 trialsAuthorised or ongoing trials in the EU Clinical Trials Information System that list a product containing Vancomycin. Many trials are registered in both CTIS and ClinicalTrials.gov, so these are shown separately rather than added to the count above. Trials with a site in Ireland are listed first.
Vancomycin across our data
Ireland · EU · USThe same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.
Licensed in Ireland (HPRA)
15 single-substance products containing Vancomycin on the HPRA medicines list.
- Vancocin Matrigel 125mg Hard CapsulesFlynn Pharma Limited · PA1226/005/001 · Marketed
- Vancomycin 1000 mg Powder for concentrate for solution for infusionNoridem Enterprises Limited · PA1122/008/002 · Marketed
- Vancomycin 500 mg Powder for concentrate for solution for infusionNoridem Enterprises Limited · PA1122/008/001 · Marketed
- Vancomycin Viatris 1000 mg, powder for solution for infusionViatris Limited · PA23266/004/002 · Marketed
- Vancomycin Viatris 500 mg, powder for solution for infusionViatris Limited · PA23266/004/001 · Marketed
Supply shortages
- Vancomycin Hydrochloride InjectionUS (FDA) · Resolved · updated 14 Nov 2025
- Vancomycin CP 500mgGermany (BfArM) · Other reason · 15 Jan 2025 to 30 Nov 2026
Conditions studied with Vancomycin
44 conditionsAll 44 conditions
| Condition (as registered) | Trials |
|---|---|
| Staphylococcus Aureus Bacteremia | 2 |
| Melanoma | 1 |
| Osteomyelitis (Refractory) | 1 |
| Immunotherapy | 1 |
| HCC - Hepatocellular Carcinoma | 1 |
| Antibiotic Prophylaxis | 1 |
| General Surgery | 1 |
| Febrile Neutropenia (FN) | 1 |
| Pediatric Cancer | 1 |
| Hematologic Malignancies | 1 |
| Solid Tumors | 1 |
| Primary Sclerosing Cholangitis | 1 |
| Liver and Intrahepatic Bile Duct Disorder | 1 |
| IBD | 1 |
| C. Difficile | 1 |
| C. Difficile Infection | 1 |
| Controlled Human Infection | 1 |
| Arthroplasty, Replacement, Hip | 1 |
| Osteoarthritis, Hip | 1 |
| Antibiotic Resistant Infection | 1 |
| Prosthetic Joint Infection | 1 |
| Metastatic Castration-Resistant Prostate Cancer (mCRPC) | 1 |
| Clostridioides Difficile Infection | 1 |
| Ulcerative Colitis (UC) | 1 |
| Primary Sclerosing Cholangitis (PSC) | 1 |
| Clostridia Difficile Colitis | 1 |
| Open Fracture | 1 |
| Trauma | 1 |
| Infection, Surgical Site | 1 |
| Fractures, Open | 1 |
| Staphylococcus Aureus Septicemia | 1 |
| S. Aureus Bacteremia | 1 |
| S. Aureus Bloodstream Infection | 1 |
| MRSA | 1 |
| Spine Disease | 1 |
| ADHD | 1 |
| ADHD - Attention Deficit Disorder With Hyperactivity | 1 |
| ADHD - Combined Type | 1 |
| Vaccine Response Impaired | 1 |
| Infection | 1 |
| Hydrocephalus | 1 |
| Ventriculoperitoneal Shunt Infection | 1 |
| Surgical Site Infection (SSI) | 1 |
| Cerebrospinal Fluid Shunt Infection | 1 |
Sponsors
lead sponsor per trial+ 6 more sponsors in the trial list above.
By country register
A trial with sites in more than one country appears in each of those registers. CTIS does not publish a recruiting flag; its trials may also appear in the registers above.
Related compounds
Questions about Vancomycin trials
How many clinical trials are testing Vancomycin?
21 current trials in our Canada, France, Australia, Spain, Italy, Germany, Netherlands, Sweden, Israel, Switzerland, Egypt, UK, China, Japan and Singapore registers name Vancomycin as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.
Are Vancomycin trials recruiting patients?
Yes. 14 of the 21 trials are recruiting: 6 with sites in Canada, 2 with sites in France, 3 with sites in Australia, 1 with sites in Italy, 2 with sites in Germany, 1 with sites in Netherlands, 2 with sites in Sweden, 2 with sites in Israel, 2 with sites in Switzerland, 1 with sites in Egypt, 1 with sites in Japan and 1 with sites in Singapore. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Vancomycin clinical trials?
Microbiotica Ltd (1), Second Affiliated Hospital, Zhejiang University, School of Medicine (1), University of Melbourne (1) and Michael Dill (1), among 21 lead sponsors in total. The number in brackets is how many trials each organisation leads.
Is Vancomycin licensed in Ireland?
Yes. The HPRA medicines list includes 15 single-substance products containing Vancomycin, for example Vancocin Matrigel 125mg Hard Capsules (Flynn Pharma Limited). A licence does not mean a product is currently marketed or reimbursed; see each product's record.
Is there a Vancomycin shortage?
The registers we track list 2 entries for Vancomycin: US FDA: resolved; 1 German notice. Shortages are product- and country-specific; check with a pharmacist.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Vancomycin works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Vancomycin works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Vancomycin (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.