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Trackers› Clinical trials› Hamilton
Clinical trial register · Canada

Clinical Trials in Hamilton, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Canada and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 6553 matching records held by the registry are in this view. Synced 10 Nov 2026, 03:20 UTC
6553
Studies in scope
all four open statuses
3487
Recruiting now
open to new participants
880
Lead sponsors
across recruiting studies
Top sites
Toronto 2818 Montreal 1913 Vancouver 1187 Calgary 1068 Edmonton 1018
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
McMaster University109 AstraZeneca46 Canadian Cancer Trials Group32 National Cancer Institute (NCI)26 Population Health Research Institute24 St. Joseph's Healthcare Hamilton24 Hamilton Health Sciences Corporation23 Children's Oncology Group22 Eli Lilly and Company20 Merck Sharp & Dohme LLC19 AbbVie17 Novo Nordisk A/S17 Janssen Research & Development, LLC14 Novartis Pharmaceuticals14 Pfizer13 Bristol-Myers Squibb13 Sanofi13 University Health Network, Toronto13 Sunnybrook Health Sciences Centre10 Hoffmann-La Roche9 University of British Columbia8 Amgen7 The Hospital for Sick Children7 Incyte Corporation7 University of Pennsylvania7 Ottawa Hospital Research Institute7 Edwards Lifesciences6 Regeneron Pharmaceuticals6 Boehringer Ingelheim5 Ottawa Heart Institute Research Corporation5 University of Calgary5 Ontario Clinical Oncology Group (OCOG)5 Alliance for Clinical Trials in Oncology4 NRG Oncology4 Takeda4 GlaxoSmithKline4 Dr. Kerstin de Wit3 Nova Scotia Health Authority3 Celldex Therapeutics3 Celgene3 Mount Sinai Hospital, Canada3 BeOne Medicines3 London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's3 Bayer3 CSL Behring3 Sir Mortimer B. Davis - Jewish General Hospital3 Agios Pharmaceuticals, Inc.3 Alimentiv Inc.2 University of Alberta2 European Organisation for Research and Treatment of Cancer - EORTC2 Akero Therapeutics, Inc2 Weill Medical College of Cornell University2 Maastricht University2 Otsuka Pharmaceutical Development & Commercialization, Inc.2 Genentech, Inc.2 Mirum Pharmaceuticals, Inc.2 Canadian Myeloma Research Group2 Jeffrey Pernica2 Karuna Therapeutics, Inc., a Bristol Myers Squibb company2 St. Justine's Hospital2 Centre hospitalier de l'Université de Montréal (CHUM)2 Joseph Broderick, MD2 University of Maryland, Baltimore2 University of Manitoba2 SWOG Cancer Research Network2 Epineuron Technologies Inc.2 AtriCure, Inc.2 Exelixis2 PharmaEssentia2 Montreal Heart Institute2 Western University, Canada2 Alnylam Pharmaceuticals2 FluidAI Medical2 LEO Pharma2 United Therapeutics2 ArthroBiologix Inc.2 Ferring Pharmaceuticals2 McGill University2 Université de Sherbrooke2 Todd C. Lee MD MPH FIDSA2 Deciphera Pharmaceuticals, LLC2 Holland Bloorview Kids Rehabilitation Hospital2 Abraham Nunes1 University College, London1 University of Sydney1 pharmaand GmbH1 Assistance Publique - Hôpitaux de Paris1 Tesaro, Inc.1 M.A. Med Alliance S.A.1 Columbia University1 Aesculap Biologics, LLC1 Arrowhead Pharmaceuticals1 Corcept Therapeutics1 MediciNova1 Stichting European Myeloma Network1 Unity Health Toronto1 Astellas Pharma Global Development, Inc.1 Smith & Nephew, Inc.1 University of Michigan1 Dana-Farber Cancer Institute1 Mark Vincent1 C17 Council1 Vertex Pharmaceuticals Incorporated1 Day One Biopharmaceuticals, Inc.1 Abbott Medical Devices1 Parth Patel1 NoNO Inc.1 Hospital Universitari Vall d'Hebron Research Institute1 Bioverativ, a Sanofi company1 Alpine Immune Sciences Inc, A Subsidiary of Vertex1 Horizon Health Network1 Dinesh Thavendiranathan1 Ostia Sciences1 Gilead Sciences1 Vega Therapeutics, Inc1 Basilea Pharmaceutica1 Baylor College of Medicine1 Zentrela Inc.1 Biosensors Europe SA1 Juno Therapeutics, Inc., a Bristol-Myers Squibb Company1 Douglas Mental Health University Institute1 Aerogen Pharma Limited1 P.J. Devereaux1 Abiomed Inc.1 Institut universitaire de cardiologie et de pneumologie de Québec, University Laval1 Oruka Therapeutics, Inc.1 Bold Therapeutics, Inc.1 Karen Rowa1 Peter Merkel1 University of Guelph1 Memorial Sloan Kettering Cancer Center1 Javelin Medical1 Waleed Alqurashi1 Boston Scientific Corporation1 TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)1 Centre for Addiction and Mental Health1 Arcus Biosciences, Inc.1 Amylyx Pharmaceuticals Inc.1 Inventiva Pharma1 Dr. Stephanie Sibley1 Erasmus Medical Center1 West Park Healthcare Centre1 DiaMedica Therapeutics Inc1 Jerry Zimmerman1 Sumitomo Pharma America, Inc.1 Sonia Anand1 Diagram B.V.1 Theralase® Technologies Inc.1 Jonathan Troy Grennan1 Children's Hospital of Eastern Ontario1 University of Waterloo1 Ipsita Goswami1 Dicerna Pharmaceuticals, Inc., a Novo Nordisk company1 Eisai Inc.1 Queen's University1 Naveen Poonai1 Actelion1 Savara Inc.1 Masaryk University1 ECOG-ACRIN Cancer Research Group1 Chronicle Academy1 Massachusetts General Hospital1 Verve Therapeutics, Inc.1 World Health Research Inc.1 Donald Arnold1 Stanford University1 Institut de Recherches Cliniques de Montreal1 Elion Therapeutics, Inc.1 Maastricht University Medical Center1 Region Skane1 Habib Khan1 Orthopaedic Innovation Centre1 McGill University Health Centre/Research Institute of the McGill University Health Centre1 Conjupro Biotherapeutics, Inc.1 Bellus Health Inc. - a GSK company1 Equilibra Bioscience LLC1 ALX Oncology Inc.1 Sheila Sprague1 Anthony Bai1 Birch BioMed Inc1 Donald Mabbott1 NovoCure GmbH1 NS Pharma, Inc.1 Hyivy Health Inc1 TIDHI Innovation Inc.1 Prilenia1 Alumis Inc1 Biogen1 Michelle Zeller1 Leiden University Medical Center1 Isabella Jaramillo1 Michelle Baczynski1 University of Pittsburgh1 Moin Khan1 Bioventus LLC1 Vedanta Biosciences, Inc.1 Suzanne Schuh1 Teva Branded Pharmaceutical Products R&D LLC1 Kirsten Bell1 Panam Clinic1 Genmab1 Alexion Pharmaceuticals, Inc.1 Madrigal Pharmaceuticals, Inc.1 Avalyn Pharma Inc.1 UMC Utrecht1 DBV Technologies1 McMaster Children's Hospital1 UCB Biopharma SRL1 Nocion Therapeutics1 Melanoma and Skin Cancer Trials Limited1 Prostate Cancer Clinical Trials Consortium1 ImmunoVaccine Technologies, Inc. (IMV Inc.)1 Gaylan Rockswold1 Indiana University1 Tanja Andrea Gruber1 Insel Gruppe AG, University Hospital Bern1 Aragon Pharmaceuticals, Inc.1 Octapharma1 Royal Marsden NHS Foundation Trust1 IGC Pharma, LLC1 University of Toronto1
Site location
Toronto2818 Montreal1913 Vancouver1187 Calgary1068 Edmonton1018 Ottawa884 London878 Hamilton811 Québec682 Halifax535 Winnipeg454 Sherbrooke264 Kingston254 Kelowna176 Brampton143 Surrey138 Victoria129 St. John's126 Barrie125 Saskatoon125 Chicoutimi100 Moncton92 Mississauga89 Greater Sudbury83 Regina82 Trois-Rivières80 Saint John75 Greenfield Park73 Oshawa73 New Westminster70 Newmarket68 North York64 Markham61 Ajax60 Windsor55 Lévis53 Kitchener49 Fredericton49 Oakville48 Waterloo47 Guelph42 Rimouski39 Burlington37 Peterborough37 Abbotsford British Columbia36 Sarnia34 Red Deer33 Scarborough Village32 Laval30 Cambridge30 Richmond Hill30 Etobicoke26 Vaughan26 Thunder Bay26 Gatineau24 Prince George22 Sault Ste. Marie21 North Vancouver20 Richmond20 Burnaby19 Sherwood Park18 Lethbridge18 Verdun18 Whitby17 Niagara Falls17 North Bay17 Sydney16 St. Catharines14 Stouffville13 Saint-Jérôme13 Saint-Charles-Borromée13 Longueuil13 Stoney Creek12 Concord11 Kentville11 Truro10 Terrebonne10 Penticton10 Courtice9 Mount Royal9 Kamloops9 Mirabel8 Victoriaville8 St. Albert7 Saint Catharines7 Winchester7 Joliette6 Brandon6 Dartmouth6 West Vancouver6 Bridgewater6 Saguenay6 Medicine Hat6 Thornhill6 Brantford5 Pointe-Claire5 Orillia5 Westmount5 Cobourg5 East York5 Nanaimo5 Ontario5 Nova Scotia4 Owen Sound4 Chilliwack4 Montral4 North YORK4 Scarborough4 Boisbriand4 Multiple Locations4 Woodbridge4 Granby4 Langley4 Sainte-Foy4 New Minas3 Canmore3 Dieppe3 Ste-Foy3 Decarie Montreal3 Many Locations3 Grande Prairie3 Winnepeg3 Chatham2 Stratford2 Belleville2 Nepean2 Saint Johns2 Saint-Georges2 Fort McMurray2 Cranbrook2 Hawkesbury2 Dundas2 Sainte-Marie2 Okanagan2 SaintJerome2 Pembroke2 Pierrefonds2 Bedford2 Alberta2 Banff2 Jonquière2 Saint-Laurent2 Edmundston2 Montréal2 Niagara2 Hanover1 Renfrew1 Drummondville1 Maria1 Miramichi1 Penetanguishene1 Norway House1 Baie-Saint-Paul1 La Malbaie1 Edmonton & Calgary1 Multiple1 North Van Couver1 Grand Prairie1 Mississagua1 Saint Isidore1 Bowmanville1 Coxheath1 Lai Chi Kok1 Sioux Lookout1 Wawa1 Piikani Nation1 Flying Dust First Nation1 Ministikwan Lake1 Onion Lake1 Waterhen Lake1 Greenville1 Fleurimont1 Saint Catherines1 Prince Albert1 Calgery1 Frederiction1 Vancouver BC1 Prince Rupert1 Sept-Îles1 Ville-Marie1 Orangeville1 Whistler1 Egypt1 Port Perry1 Newcastle1 Mira Road1 Happy Valley-Goose Bay1 Norris Point1 Woodstock1 High River1 Antigonish Nova Scotia1 Saint Jerome Quebec1 Airdrie1 Burin1 Clarenville1 Hailfax1 Alliston1 Cowansville1 Saint-Hyacinthe1 Montr Al1 Kanata1 Pickering1 Columbia1 Charlottetown1 Dalhousie1 Carbonear1 Cornwall1 Limoges1 Orléans1 Aurora1 Mission1 Dorchester1 Smiths Crossing1 Moose Jaw1 Fort Erie1 Kelowna BC1 Coburg1 Tiny1 Ganges1 Bathurst1 Bouctouche1 Campbellton1 Caraquet1 Grand Falls1 Saint-Quentin1 Pierrefonds-Roxboro1 Edmonton AB1 Montréal1 Châteauguay1 Portage la Prairie1 Denver1 Winnipeg MB1 Brockville1 Montreal, Quebec1 Weston1 Gloucester1 Emo1 Dryden1 Fort Frances1 Lakefield1 Napanee1 Hamitlon1 Laurier1 Hagersville1 Strathroy1 West Hamilton1 Don Mills1 Val-d'Or1
All 248 locations
Target enrolment
to

Trials with a site in Hamilton

811 of 6553 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
Sites in Canada
Start
Recruiting
Birch BioMed Inc
Phase 2/3
70
Edmonton, Hamilton
2027-03
Not yet open
Transition Coaching in Rheumatology
NCT07838896Rheumatic Conditions
McMaster University
Not applicable
86
Hamilton
2027-03
Not yet open
McMaster University
Not applicable
30
Hamilton
2027-01-01
Not yet open
Stellate Ganglion Neuromodulation for the Treatment of Electrical Storm
NCT07857889Ventricular Tachycardia (V-Tach) Storm
Population Health Research Institute
Not applicable
300
Hamilton
2027-01
Not yet open
Bristol-Myers Squibb
Phase 3
2,380
Sherwood Park, Vancouver, Burlington, Hamilton, Owen Sound, Toronto, Greenfield Park, Montreal
2026-12-16
Not yet open
McMaster University
Not applicable
24
Hamilton
2026-12-01
Not yet open
St. Joseph's Healthcare Hamilton
Phase 1/2
89
Hamilton
2026-12-01
Not yet open
Institut de Recherches Cliniques de Montreal
Not applicable
63
Edmonton, Hamilton, Montreal
2026-12
Not yet open
AI-Adaptive AR Training for Balance and Falls Prevention in Older Adults
NCT07781995Older Adults, Older Adults, Balance
McMaster University
Not applicable
30
Hamilton
2026-11-30
Not yet open
Novo Nordisk A/S
Phase 3
1,408
Vancouver, Victoria, Moncton, Halifax, Hamilton, London, Trois-Rivières, Québec
2026-11-11
Recruiting
Sex Differences in BDNF Study
NCT07912307Exercise, BDNF, Sex Differences
McMaster University
Not applicable
50
Hamilton
2026-11
Recruiting
McMaster University
Phase 4
80
Hamilton
2026-10-31
Recruiting
Novo Nordisk A/S
Phase 3
84
Vancouver, Hamilton, Toronto
2026-10-16
Not yet open
McMaster University
Phase 4
966
Hamilton
2026-10-15
Not yet open
Internet-Delivered CBT Program for Menopausal Vasomotor Symptoms
NCT07873177Menopause, Menopausal Vasomotor Symptoms
St. Joseph's Healthcare Hamilton
Not applicable
50
Hamilton
2026-10-13
Not yet open
Antireflux Surgery Without Preoperative Esophageal Manometry
NCT07659080GERD, Hiatal Hernia, Heartburn, Paraesophageal Hernia
McMaster University
Not applicable
96
Hamilton
2026-10-01
By invitation
Personalized Probiotic Treatments for Irritable Bowel Syndrome
NCT07872514Irritable Bowel Syndrome (IBS)
McMaster University
Not applicable
30
Hamilton
2026-10
Recruiting
ACSS Approach on Dysphagia
NCT07533864Anterior Cervical Spine Surgery
Hamilton Health Sciences Corporation
Observational
100
Hamilton
2026-10
Recruiting
Holland Bloorview Kids Rehabilitation Hospital
Phase 2
100
Hamilton, Kingston, London, Toronto
2026-10
Not yet open
McMaster University
Phase 4
124
Calgary, Hamilton, London, Québec, Sherbrooke
2026-09-30
Not yet open
Group CBT for Paternal Perinatal Depression
NCT07758036Perinatal Depression, Fathers
McMaster University
Not applicable
112
Hamilton
2026-09-15
Recruiting
Takeda
Phase 3
324
Calgary, Hamilton, London, Toronto, Lévis, Montreal
2026-09-10
By invitation
Family Accommodation Reduction in Adult Obsessive Compulsive Disorder
NCT07912177Obsessive - Compulsive Disorder, Family Accommodation, OCD, CBT
Karen Rowa
Not applicable
480
Hamilton, North York
2026-09-10
Recruiting
Incyte Corporation
Phase 3
426
Vancouver, Hamilton, Kingston, Toronto, Montreal, Québec
2026-09-08
Recruiting
Head of Bed After Ischemic Stroke Thrombectomy (HoBIT)
NCT07367633Large Vessel Occlusion, Stroke, Ischemic Stroke
Population Health Research Institute
Not applicable
2,240
Greater Sudbury, Hamilton
2026-09-03
Not yet open
Eye Patient Adherence and Compliance Study
NCT07793474Glaucoma Medication Adherence, Glaucoma Patients
St. Joseph's Healthcare Hamilton
Not applicable
189
Hamilton
2026-09-01
Recruiting
Partner4Exercise Study
NCT07408128Cancer
McMaster University
Phase 2/3
183
Hamilton
2026-09-01
Not yet open
Rhythm Psychophysics With Parkinson's Patients
NCT07647913Parkinson Disease(PD)
McMaster University
Not applicable
34
Hamilton
2026-09-01
Not yet open
St. Joseph's Healthcare Hamilton
Not applicable
120
Hamilton
2026-09
Not yet open
McMaster University
Not applicable
64
Hamilton
2026-09
Recruiting
McMaster University
Not applicable
50
Hamilton
2026-08-27
Recruiting
AstraZeneca
Phase 3
500
Calgary, Surrey, Vancouver, Guelph, Hamilton, Stouffville, Toronto, Joliette
2026-08-24
Recruiting
Canadian Cancer Trials Group
Phase 2
40
Calgary, Edmonton, Vancouver, Hamilton, Toronto
2026-08-24
Recruiting
Novartis Pharmaceuticals
Phase 3
180
Hamilton, Québec
2026-08-24
Recruiting
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
NCT07761117Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
DrugElecoglipron
AstraZeneca
Phase 3
6,950
Barrie, Etobicoke, Greater Sudbury, Hamilton, Kingston, London, Markham, Newmarket
2026-08-24
Recruiting
AstraZeneca
Phase 3
1,500
Calgary, Vancouver, Moncton, Truro, Hamilton, Markham, North York, Sarnia
2026-08-20
Recruiting
McMaster University
Not applicable
30
Hamilton
2026-08-18
Recruiting
AstraZeneca
Phase 3
600
Hamilton, Scarborough Village, Stouffville, Chicoutimi, Sherbrooke, Victoriaville
2026-08-12
Recruiting
Regeneron Pharmaceuticals
Phase 3
15,364
Hamilton, Sherbrooke, Longueuil
2026-08-10
Not yet open
Prevention of Vascular Graft Infection With Hypochlorous Acid
NCT07678632Vascular Prosthetic Graft Infection
Hamilton Health Sciences Corporation
Not applicable
500
Hamilton
2026-08-03
Not yet open
Tirzepatide in the Treatment of Cannabis Use Disorder
NCT07671248Cannabis Use Disorder, Moderate, Cannabis Use Disorder, Severe
DrugTirzepatide
McMaster University
Phase 3
15
Hamilton
2026-08-01
Recruiting
Amgen
Phase 3
950
Hamilton
2026-07-29
Recruiting
Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment
NCT07444567Asthma, Eosinophilic Granulomatosis With Polyangiitis (EGPA), Hypereosinophilic Syndrome (HES)
DrugsFasenra·Benralizumab
AstraZeneca
Phase 3
230
Calgary, Hamilton, Toronto
2026-07-24
Recruiting
Amgen
Phase 3
3,200
Hamilton, Thunder Bay, Chicoutimi
2026-07-23
Recruiting
McMaster University
Not applicable
40
Hamilton
2026-07-22
Not yet open
McMaster University
Not applicable
16
Hamilton
2026-07-20
By invitation
Zentrela Inc.
Observational
30
Hamilton
2026-07-20
Recruiting
AstraZeneca
Phase 3
915
Calgary, Abbotsford British Columbia, Barrie, Hamilton, Kingston, London, Mississauga, Montreal
2026-07-16
Recruiting
McMaster University
Not applicable
30
Hamilton
2026-07-07
Recruiting
Pfizer
Phase 1
120
Calgary, Hamilton, Toronto
2026-07-01
Not yet open
University of British Columbia
Not applicable
240
Langley, Vancouver, Hamilton
2026-07-01
Active, closed
Boehringer Ingelheim
Phase 2
344
Surrey, Victoria, Guelph, Hamilton, London, Stouffville, Toronto, Chicoutimi
2026-06-30
Recruiting
AstraZeneca
Phase 3
4,500
Calgary, Vancouver, Victoria, Moncton, Truro, Brampton, Hamilton, Niagara Falls
2026-06-29
Recruiting
Hoffmann-La Roche
Phase 3
380
Hamilton
2026-06-23
Recruiting
Investigation of Vancomycin Efficacy in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis
NCT07341282Ulcerative Colitis (UC), Primary Sclerosing Cholangitis (PSC)
DrugVancomycin
McMaster University
Phase 2
14
Hamilton
2026-06-17
Recruiting
McMaster University
Not applicable
64
Hamilton
2026-06-15
Recruiting
Pfizer
Phase 3
954
Surrey, Moncton, Hamilton, Toronto
2026-06-10
Recruiting
Genentech, Inc.
Phase 2
162
Hamilton
2026-06-05
Recruiting
McMaster University
Not applicable
10
Hamilton
2026-06-01
Not yet open
Prehabilitation Before Major Surgery
NCT07590141Prehabilitation, Preoperative Care, Elective Surgical Procedures, Postoperative Complications
Queen's University
Not applicable
120
Hamilton, Kingston, Ottawa
2026-06-01
Not yet open
St. Joseph's Healthcare Hamilton
Not applicable
72
Hamilton
2026-06
Not yet open
Extended Group Written Exposure Therapy for Comorbid PTSD and BPD (Traits)
NCT07576387Posttraumatic Stress Disorder (PTSD), Borderline Personality Disorder (BPD)
St. Joseph's Healthcare Hamilton
Not applicable
63
Hamilton
2026-06
Not yet open
Vascular Events in Noncardiac Surgery Patients Cohort Evaluation Study 2
NCT07300579Myocardial Injury After Noncardiac Surgery (MINS), Bleeding Independently Associated With Mortality After Noncardiac Surgery (BIMS), Sepsis, Infection Without Sepsis
Hamilton Health Sciences Corporation
Observational
20,000
Hamilton
2026-06
Recruiting
Janssen Research & Development, LLC
Phase 3
644
Edmonton, Vancouver, Kentville, Barrie, Hamilton, London, Toronto, Montreal
2026-05-23
Recruiting
Canadian Cancer Trials Group
Observational
1,000
Calgary, Edmonton, Kelowna, Prince George, Vancouver, Victoria, Saint John, Hamilton
2026-05-15
Recruiting
Novo Nordisk A/S
Phase 3
5,610
Calgary, Vancouver, Winnipeg, Moncton, Halifax, Burlington, Courtice, Hamilton
2026-05-11
Recruiting
Ontario Clinical Oncology Group (OCOG)
Phase 2
162
Hamilton, Ottawa, Toronto, Montreal
2026-05-06
Recruiting
AstraZeneca
Phase 3
420
Calgary, Vancouver, Halifax, Hamilton, Toronto, Montreal, Québec
2026-05-05
Recruiting
Ostia Sciences
Not applicable
60
Hamilton
2026-05-04
Recruiting
Merck Sharp & Dohme LLC
Phase 3
876
Hamilton, Kingston, Ottawa, Montreal
2026-05-04
Recruiting
AstraZeneca
Phase 3
670
Edmonton, Halifax, Hamilton, Toronto, Montreal
2026-05-04
Recruiting
Falls Validation Study
NCT07536906Intracranial Bleed, Falls
Dr. Kerstin de Wit
Observational
4,000
Hamilton, Kingston, Ottawa, Toronto, Montreal, Québec
2026-05-01
Not yet open
Feasibility of the TransitionED Framework for Youth and Young Adults With Eating Disorders
NCT07518641Eating Disorders in Adolescence, Transition of Care
McMaster University
Not applicable
60
Calgary, Hamilton
2026-05
Recruiting
McMaster University
Not applicable
90
Hamilton
2026-04-28
Recruiting
Janssen Research & Development, LLC
Phase 3
530
Edmonton, Vancouver, Hamilton, London, Oshawa, Toronto, Montreal
2026-04-21
Recruiting
Pediatric Evaluation and Registry for Liver Cholestasis in Canada
NCT07411716PFIC - Progressive Familial Intrahepatic Cholestasis, Alagille Syndrome (ALGS), Cholestasis, Intrahepatic
Children's Hospital of Eastern Ontario
Observational
220
Calgary, Edmonton, Vancouver, Winnipeg, St. John's, Halifax, Hamilton, London
2026-04-21
Recruiting
Alimentiv Inc.
Phase 4
60
Vancouver, Hamilton, London, Scarborough Village
2026-04-20
Recruiting
Remibrutinib Open Label Roll-over Post-trial Access Protocol
NCT07456891Indication of the Parent Protocol
DrugRemibrutinib
Novartis Pharmaceuticals
Phase 3
650
Fredericton, Hamilton, London, Québec, Verdun
2026-04-16
Recruiting
PromotIng Optimal Treatment for Community-acquired PNeumonia in EmErgency Rooms
NCT07099976Community-Acquired Pneumonia (CAP), Pneumonia
Jeffrey Pernica
Not applicable
698
Calgary, Edmonton, Vancouver, Hamilton, Ottawa, Toronto
2026-04-15
Recruiting
AstraZeneca
Phase 3
245
Calgary, Richmond, Winnipeg, Hamilton, Toronto
2026-04-13
Recruiting
Novo Nordisk A/S
Phase 3
400
Calgary, Guelph, Hamilton, Trois-Rivières, Québec
2026-04-13
Recruiting
Incyte Corporation
Phase 3
588
Hamilton, Kingston, Toronto, Montreal, Québec
2026-04-09
Recruiting
Regeneron Pharmaceuticals
Phase 3
2,628
Hamilton
2026-04-03
Not yet open
Family STEPS: Family Check-Up+
NCT07433361Child Behavior Problem
McMaster University
Not applicable
300
Hamilton
2026-04-01
Not yet open
Cognitive Processing Therapy for Childbirth-Related Post-Traumatic Stress Disorder
NCT07495228Childbirth-Related Posttraumatic Stress Disorder, Childbirth-related Trauma
St. Joseph's Healthcare Hamilton
Not applicable
29
Hamilton
2026-04-01
Not yet open
Using Music During Wound Care Among Seniors With Pressure Injuries
NCT07456618Pressure Injuries, Pressure Injury, Pressure Ulcer (PU)
McMaster University
Not applicable
50
Burlington, Hagersville, Hamilton, Mississauga, North York, Stoney Creek, Strathroy, Toronto
2026-04-01
Recruiting
Arrowhead Pharmaceuticals
Phase 2
36
Vancouver, Calgary, Edmonton, Hamilton, Québec, Saskatoon
2026-03-30
Recruiting
Hoffmann-La Roche
Phase 3
2,000
Calgary, Surrey, Brampton, Hamilton, Sarnia, Trois-Rivières, Québec
2026-03-16
By invitation
McMaster University
Observational
118
Hamilton
2026-03-11
Recruiting
Multiprofen-CC to Reduce Pain in Hand Arthritis
NCT06966206Hand Osteoarthritis
St. Joseph's Healthcare Hamilton
Phase 3
42
Hamilton
2026-03-09
Recruiting
McGill University
Not applicable
120
Hamilton, Laval
2026-03-09
Recruiting
Incyte Corporation
Phase 3
700
Edmonton, Hamilton, Toronto, Greenfield Park, Lévis, Saint-Jérôme, Saskatoon
2026-03-05
Recruiting
St. Joseph's Healthcare Hamilton
Not applicable
20
Brantford, Dundas, Hamilton
2026-02-25
Active, closed
Pfizer
Phase 3
1,078
Etobicoke, Hamilton, Toronto, Mirabel
2026-02-24
Recruiting
Elion Therapeutics, Inc.
Phase 2
60
Vancouver, Hamilton, Toronto
2026-02-13
Recruiting
McMaster University
Not applicable
20
Hamilton
2026-02-10
Recruiting
A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis
NCT07201922Familial Pulmonary Fibrosis, Interstitial Lung Abnormalities, Interstitial Lung Diseases
DrugNerandomilast
Boehringer Ingelheim
Phase 3
80
Hamilton, Montreal
2026-02-10
Recruiting
Eli Lilly and Company
Phase 3
1,000
Calgary, Hamilton, Kelowna, Lévis, Montreal, Ottawa, Québec, Richmond
2026-02-09
Recruiting
Eli Lilly and Company
Phase 3
1,980
Brampton, Courtice, Guelph, Hamilton, Québec, Sarnia, Stoney Creek, Trois-Rivières
2026-02-06
Not yet open
St. Joseph's Healthcare Hamilton
Not applicable
80
Hamilton
2026-02-04
Recruiting
Janssen Research & Development, LLC
Phase 3
400
Calgary, Vancouver, Halifax, Hamilton, London, Toronto, Montreal
2026-02-04
Recruiting
Prilenia
Phase 3
500
Montreal, Edmonton, Hamilton
2026-02-01
Recruiting
Switching to the IL-23 Inhibitor Guselkumab for People With Active IBD Who Previously Used Ustekinumab (SHIFT-IBD)
NCT07245394Inflammatory Bowel Disease (IBD), Crohn Disease (CD), Ulcerative Colitis (UC), IBD-unclassified (IBD-U)
DrugsTremfya·Guselkumab
TIDHI Innovation Inc.
Observational
200
Calgary, Fredericton, Hamilton, Barrie, Brampton, London, Mississauga, Oakville
2026-01-29
Active, closed
Eli Lilly and Company
Phase 3
600
Brampton, Courtice, Hamilton, Joliette, London, Québec, Sherbrooke, Toronto
2026-01-24
Recruiting
BeOne Medicines
Phase 3
500
Victoria, Hamilton, Montreal, Québec, Sherbrooke
2026-01-22
Active, closed
CSL Behring
Phase 2
84
Calgary, Hamilton, Winnipeg
2026-01-22
Recruiting
Sanofi
Phase 3
751
Edmonton, Hamilton, London, New Westminster, Toronto
2026-01-22
Recruiting
Vorasidenib Maintenance for IDH Mutant Astrocytoma
NCT06809322IDH-mutant Grade 2 or 3 Astrocytoma
DrugVorasidenib
European Organisation for Research and Treatment of Cancer - EORTC
Phase 3
468
Calgary, Edmonton, Vancouver, Winnipeg, Halifax, Hamilton, Kingston, London
2026-01-16
Recruiting
Sanofi
Phase 3
751
Toronto, Edmonton, Hamilton, London, New Westminster
2026-01-16
Recruiting
Javelin Medical
Not applicable
2,000
Hamilton, London
2026-01-09
Recruiting
Treating Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: Ablation or Medication
NCT07272902Atrial Fibrillation (AF), Heart Failure With Mildly Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction (HFPEF), Rate Control
Nova Scotia Health Authority
Not applicable
84
Halifax, Hamilton, London, Montreal
2026-01-01
Not yet open
Assessing Spinal Accessory Nerve Recovery After Post-operative Electrical Stimulation
NCT07074392Head and Neck Cancer, Nerve Injury, Neck Dissection
McMaster University
Not applicable
38
Hamilton
2026-01-01
Recruiting
St. Joseph's Healthcare Hamilton
Not applicable
150
Hamilton
2026-01-01
Recruiting
AstraZeneca
Phase 3
1,100
Edmonton, Hamilton, Kingston, Montreal, Québec
2025-12-29
Active, closed
UCB Biopharma SRL
Phase 2
165
Edmonton, Hamilton, Toronto, Vancouver
2025-12-29
Recruiting
Eli Lilly and Company
Phase 3
800
Hamilton, Québec, Toronto, Vancouver
2025-12-22
Active, closed
Pfizer
Phase 3
3,578
Etobicoke, Hamilton, Toronto, Mirabel
2025-12-19
Active, closed
Amgen
Phase 3
250
Calgary, Brampton, Hamilton, Trois-Rivières
2025-12-19
Recruiting
Sanofi
Phase 3
85
Hamilton, Toronto, Montreal
2025-12-18
Active, closed
Oral Mucositis Management in Patients Receiving Radiation for Head and Neck Cancer: An Evaluation of a Barrier Based Treatment
NCT07697287Squamous Cell Carcinoma, Oropharyngeal Cancers, Nasopharyngeal Cancer, Hypopharyngeal Cancer
McMaster University
Phase 4
29
Hamilton
2025-12-15
Recruiting
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
NCT07218380Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Neoplasm Metastasis
DrugsVepugratinib·Pembrolizumab
Eli Lilly and Company
Phase 3
450
Calgary, Hamilton, Québec, Vancouver
2025-12-12
Recruiting
Real-world Secukinumab Outcomes in Canadian HS Patients
NCT07282015Hidradenitis Suppurativa
Novartis Pharmaceuticals
Observational
142
Calgary, Winnipeg, Fredericton, St. John's, Cobourg, Hamilton, London, Markham
2025-12-12
Recruiting
Canadian Consortium on Airway Mucus Occlusions in Asthma, COPD and Chronic Cough
NCT06858748Asthma, Chronic Obstructive Pulmonary Disease (COPD), Chronic Cough (CC)
McMaster University
Observational
240
Vancouver, Hamilton, London, Ottawa, Montreal, Québec, Sherbrooke
2025-12-11
Recruiting
AstraZeneca
Phase 2
230
Edmonton, Vancouver, Victoria, Halifax, Hamilton, London, Montreal, Québec
2025-12-10
Recruiting
Intravascular Ultrasound for Peripheral Artery Disease Revascularization
NCT06979284Peripheral Arterial Disease(PAD), Chronic Limb Threatening Ischemia, Intravascular Ultrasound, Major Adverse Limb Events
Hamilton Health Sciences Corporation
Not applicable
772
Montreal, Sherbrooke, Hamilton, Toronto
2025-12-05
Recruiting
Bristol-Myers Squibb
Phase 3
650
Hamilton, London, Toronto, Whitby
2025-12-02
Not yet open
Hip Fracture Surgery Arterial and Venous Thrombotic Events Prevention
NCT07228663Hip Fracture Surgery, Cardiovascular Prevention, Venous Thromboembolism (VTE)
DrugsDirect Anticoagulant·Dalteparin·DOAC·Tinzaparin
McMaster University
Phase 3
100
Hamilton
2025-12-01
Recruiting
Michelle Baczynski
Not applicable
780
Calgary, Edmonton, Vancouver, Hamilton, London, Toronto, Montral, Montreal
2025-12-01
Recruiting
Eli Lilly and Company
Phase 3
7,140
Brampton, Cambridge, Chicoutimi, Hamilton, Laval, Moncton, Montreal, Québec
2025-12-01
Recruiting
St. Joseph's Healthcare Hamilton
Not applicable
50
Hamilton
2025-12
Active, closed
Alexion Pharmaceuticals, Inc.
Phase 2
78
Calgary, Etobicoke, Hamilton, Montreal
2025-11-26
By invitation
Celldex Therapeutics
Phase 3
1,370
Edmonton, Hamilton, Markham, North Bay, Toronto, Windsor, Kingston, Québec
2025-11-25
Recruiting
Chronicle Academy
Observational
80
Burlington, Hamilton, Kanata, Ottawa, Pickering, Saskatoon
2025-11-25
Active, closed
Amgen
Phase 3
250
Calgary, Brampton, Hamilton, Trois-Rivières
2025-11-25
Recruiting
McMaster University
Not applicable
26
Hamilton
2025-11-21
Recruiting
Ketamine Sedation in the ICU (KANINE) RCT
NCT06767358Mechanical Ventilation, Critically Ill Intensive Care Unit Patients
DrugKetamine Hydrochloride
McMaster University
Phase 3
54
Hamilton, Toronto
2025-11-20
Active, closed
Bayer
Phase 2
60
Hamilton, Montreal, Québec
2025-11-19
Recruiting
AstraZeneca
Phase 3
420
Calgary, Victoria, Hamilton, Oshawa, Ottawa, Toronto, Chicoutimi
2025-11-11
Recruiting
Eli Lilly and Company
Phase 2
252
Hamilton, London, Mississauga, Trois-Rivières
2025-11-10
Recruiting
Ottawa Hospital Research Institute
Phase 3
36
Hamilton, Ottawa
2025-11-10
Recruiting
Hamilton Health Sciences Corporation
Phase 3
30
Hamilton, London
2025-11-07
Recruiting
Sanofi
Phase 2
208
Edmonton, Sherwood Park, Kelowna, Hamilton, Toronto, Québec
2025-11-06
Active, closed
Novo Nordisk A/S
Phase 3
330
Kelowna, Moncton, Halifax, Brampton, Hamilton, London, Pointe-Claire, Victoriaville
2025-11-05
Active, closed
Novo Nordisk A/S
Phase 3
300
Moncton, Halifax, Hamilton, London, Oshawa, Toronto, Mirabel
2025-11-05
Active, closed
Takeda
Phase 2
207
Fredericton, Barrie, Hamilton, Oakville, Peterborough, Toronto, Québec, Saskatoon
2025-11-03
Recruiting
AstraZeneca
Phase 3
400
Vancouver, Moncton, Halifax, Brampton, Hamilton, Toronto
2025-10-31
Recruiting
Novartis Pharmaceuticals
Phase 2
165
Calgary, Vancouver, Halifax, Hamilton, London, Newmarket, Toronto, Montreal
2025-10-28
Recruiting
Resolving Early Life Stress: Psychotherapy Outcomes and Neurobiology in Complex Depression
NCT07250893Depression - Major Depressive Disorder, Childhood Traumas
St. Joseph's Healthcare Hamilton
Not applicable
50
Hamilton
2025-10-25
Recruiting
BoxX-NoAF Clinical Trial
NCT06989775Post Operative Atrial Fibrillation, Atrial Fibrillation, Postoperative
AtriCure, Inc.
Not applicable
960
New Westminster, Hamilton, London, Montreal
2025-10-24
Recruiting
Eli Lilly and Company
Phase 3
1,630
Calgary, Hamilton, Montreal, Sherbrooke, Surrey, Toronto
2025-10-22
Recruiting
Eli Lilly and Company
Phase 2
531
Ajax, Hamilton, Kelowna, Montreal, Québec, Richmond, Saint-Laurent, Toronto
2025-10-22
Recruiting
Canadian Cancer Trials Group
Phase 2
140
Calgary, Kelowna, Vancouver, Hamilton, Kingston, Kitchener, London, Mississauga
2025-10-21
Recruiting
Regeneron Pharmaceuticals
Phase 2
1,200
Edmonton, Victoria, Moncton, Greater Sudbury, Hamilton, Oshawa, Scarborough Village, Longueuil
2025-10-20
Recruiting
GlaxoSmithKline
Phase 1/2
47
Hamilton, Toronto, Montreal
2025-10-20
Recruiting
Suzanne Schuh
Phase 3
192
Calgary, Edmonton, Hamilton, Ottawa, Toronto, Montreal
2025-10-08
Recruiting
Sanofi
Phase 3
980
Hamilton, Oakville, Toronto
2025-10-08
Recruiting
Trial of Social Work Services in Fracture Clinic Setting
NCT06973655Orthopaedic Fractures, Socioeconomic Factors
Sheila Sprague
Not applicable
2,000
Hamilton
2025-10-06
Recruiting
Novartis Pharmaceuticals
Phase 3
300
Edmonton, Hamilton, London, Newmarket, Montreal, Québec
2025-10-03
Recruiting
Novo Nordisk A/S
Phase 3
1,280
Calgary, Vancouver, Québec, Halifax, Greater Sudbury, Hamilton, London, Mississauga
2025-10-02
Recruiting
McMaster University
Observational
54
Hamilton
2025-10-01
Not yet open
Ottawa Hospital Research Institute
Phase 2
168
Edmonton, Hamilton, Ottawa, Toronto, Montreal, Québec
2025-10-01
Recruiting
Sanofi
Phase 3
980
Oakville, Brampton, Edmonton, Greater Sudbury, Hamilton, London, Montreal, New Westminster
2025-10-01
Not yet open
McMaster University
Not applicable
2,000
Hamilton
2025-10
Not yet open
Hyivy Device as Non-hormonal Therapy in Endometriosis
NCT05643131Endometriosis, Pelvic Pain
Hyivy Health Inc
Not applicable
20
Hamilton
2025-10
Active, closed
IAMABLE: Implementation and Evaluation of an App for Evidence-Based Self-Management Rehabilitation Strategies
NCT06773169Neurological Conditions, Musculoskeletal Diseases or Conditions, Cardiovascular Diseases
McMaster University
Not applicable
50
Hamilton
2025-09-25
Recruiting
Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome
NCT06776783Respiratory Distress Syndrome, Pre-term Infants
Aerogen Pharma Limited
Phase 3
520
Edmonton, Halifax, Hamilton, Ottawa, Toronto, Québec
2025-09-24
Recruiting
Sanofi
Phase 4
35
Calgary, St. John's, Hamilton
2025-09-23
Recruiting
Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation
NCT06942039CNS Embryonal Tumor, CNS, Medulloblastoma, Atypical Teratoid Rhabdoid Tumor, Medulloblastoma, Childhood
DrugsCytarabine IT·Carbo·Mesna·Isotretinoin
C17 Council
Early Phase 1
15
Calgary, Vancouver, Winnipeg, Halifax, Hamilton, London, Ottawa, Montreal
2025-09-23
Recruiting
McMaster University
Not applicable
60
Kelowna, Hamilton
2025-09-15
Recruiting
LEO Pharma
Phase 2
135
Calgary, Edmonton, Surrey, Winnipeg, Fredericton, Hamilton, Markham, Waterloo
2025-09-11
Recruiting
Effects of Donor-recipient Sex-matched Blood Transfusion on Patient Outcomes
NCT06840756Red Blood Cell Transfusions, Sex Differences, Health Services, Critically Ill Intensive Care Unit Patients
Michelle Zeller
Phase 4
11,082
Hamilton, Kingston, London, Oshawa, Ottawa, Toronto
2025-09-11
Recruiting
AbbVie
Observational
700
Calgary, Edmonton, Winnipeg, Ajax, Belleville, Hamilton, London, Markham
2025-09-09
Active, closed
McMaster University
Not applicable
48
Hamilton
2025-09-09
Active, closed
Online Transdiagnostic Group CBT for Postpartum Depression and Anxiety
NCT07162129Postpartum Depression (PPD), Postpartum Anxiety
McMaster University
Not applicable
48
Hamilton
2025-09-09
Recruiting
Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma
NCT07011719Metastatic Clear Cell Renal Cell Carcinoma, Advanced Clear Cell Renal Cell Carcinoma
DrugsCasdatifan·Cabozantinib
Arcus Biosciences, Inc.
Phase 3
720
Calgary, Edmonton, Hamilton, London, Montreal, Sherbrooke, Toronto, Vancouver
2025-09-08
Recruiting
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
NCT07157774Elevated Lp(a), Atherosclerotic Cardiovascular Disease (ASCVD)
Eli Lilly and Company
Phase 3
10,450
Chicoutimi, Etobicoke, Hamilton, Joliette, Longueuil, Moncton, Montreal, North York
2025-09-02
Recruiting
Basilea Pharmaceutica
Phase 3
234
Edmonton, Hamilton, London, Ottawa, Toronto, Vancouver
2025-08-26
Recruiting
Deep rTMS for Mild Neurocognitive Disorder in Older Adults
NCT07038798Mild Neurocognitive Disorder
St. Joseph's Healthcare Hamilton
Not applicable
30
Hamilton
2025-08-26
Recruiting
McMaster University
Observational
300
Hamilton
2025-08-18
Active, closed
Novo Nordisk A/S
Phase 3
877
Calgary, Vancouver, Winnipeg, Halifax, Brampton, Etobicoke, Hamilton, London
2025-08-11
Recruiting
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
NCT07114601Breast Neoplasms, Colorectal Neoplasms, Prostate Neoplasm, Endometrial Neoplasms
Eli Lilly and Company
Phase 1
421
Hamilton, Montreal, Toronto
2025-08-06
Recruiting
McMaster University
Phase 1
33
Hamilton
2025-08-05
Recruiting
AstraZeneca
Phase 3
800
Edmonton, Winnipeg, Hamilton, Kingston, Montreal
2025-08-01
Recruiting
Visible Abdominal Distension
NCT06369753Irritable Bowel Syndrome, Dyspepsia, Functional Bloating
Hospital Universitari Vall d'Hebron Research Institute
Not applicable
100
Hamilton
2025-07-30
Recruiting
St. Joseph's Healthcare Hamilton
Phase 3
846
Surrey, Brockville, Hamilton, Toronto
2025-07-29
Recruiting
The Canadian Lung Outcomes in Users of Vaping Devices Study
NCT06819969Small Airways Diseases, Vaping, Vaping Related Disorder, Vaping Teens
University of British Columbia
Observational
500
Edmonton, Vancouver, Hamilton, Ottawa, Toronto, Sherbrooke
2025-07-25
Active, closed
Oruka Therapeutics, Inc.
Phase 2
80
Edmonton, Surrey, Hamilton, London, Markham, Peterborough, Toronto, Waterloo
2025-07-18
Not yet open
McMaster University
Not applicable
18
Hamilton
2025-07-15
Recruiting
Bristol-Myers Squibb
Phase 3
426
Hamilton, London, Toronto, Whitby, Montreal
2025-07-10
Recruiting
REhabilitation of MEMory Symptoms After BRain Concussion
NCT06956417Concussion, Brain, Mild Traumatic Brain Injury
University of British Columbia
Not applicable
184
Calgary, Langley, Vancouver, Hamilton, Ottawa, Toronto
2025-07-02
Active, closed
Hamilton Health Sciences Corporation
Phase 4
20
Hamilton
2025-07-02
Not yet open
McMaster University
Not applicable
10
Hamilton
2025-07-01
Not yet open
Dexmedetomidine Versus Morphine During Cooling Therapy in Neonates
NCT06985290Hypoxic Ischemic Brain Injury, Neonatal Encephalopathy, Perinatal Anoxic-ischemic Brain Injury
DrugsMorphine·Dexmedetomidine
Ipsita Goswami
Phase 2
50
Hamilton
2025-07-01
Recruiting
ACB vs no Block for Pediatric ACL Reconstruction
NCT06875427Anterior Cruciate Ligament, Anterior Cruciate Ligament (ACL) Tear
Isabella Jaramillo
Phase 3
38
Hamilton
2025-07-01
Recruiting
AstraZeneca
Phase 2
987
Edmonton, Winnipeg, Truro, Ajax, Burlington, Guelph, Hamilton, Stoney Creek
2025-06-27
Recruiting
Novo Nordisk A/S
Phase 2
200
Vancouver, Brampton, Hamilton, Mississauga, Ottawa, Toronto, Winchester, Québec
2025-06-27
Recruiting
McMaster University
Not applicable
77
Hamilton
2025-06-25
Active, closed
DBV Technologies
Phase 3
480
Winnipeg, Burlington, Hamilton, Ottawa, Toronto, Montreal, Québec
2025-06-24
Recruiting
McMaster University
Phase 4
74
Hamilton
2025-06-18
Active, closed
Incyte Corporation
Phase 3
159
Calgary, Edmonton, Surrey, Vancouver, Winnipeg, Hamilton, Toronto, Montreal
2025-06-17
Active, closed
Incyte Corporation
Phase 3
573
Edmonton, Winnipeg, Fredericton, Hamilton, London, Markham, Mississauga, Saskatoon
2025-06-12
Recruiting
Cognitive Groove (Brought to You by GERAS DANCE)
NCT06870149Frailty, Frail Older Adults, Frailty in Aging, Frailty Syndrome
McMaster University
Not applicable
250
Hamilton
2025-06-10
Recruiting
Janssen Research & Development, LLC
Phase 3
600
Calgary, Vancouver, Winnipeg, Halifax, Hamilton, London, Toronto, Montreal
2025-06-04
Recruiting
McMaster University
Phase 4
242
Hamilton, London
2025-06-02
Not yet open
A Trial of Actazin Versus PEG 3350 for Maintenance Therapy in Children With Constipation
NCT06836024Constipation - Functional, Constipation, Constipation Aggravated
DrugPEG 3350
Hamilton Health Sciences Corporation
Phase 2/3
60
Hamilton
2025-06-01
Recruiting
National Cancer Institute (NCI)
Phase 2
222
Calgary, Edmonton, Vancouver, Winnipeg, Halifax, Hamilton, Toronto, Montreal
2025-05-30
Active, closed
Eli Lilly and Company
Phase 3
586
Brampton, Hamilton, Sarnia, Sydney, Toronto
2025-05-29
Recruiting
Canadian Cancer Trials Group
Phase 3
830
Edmonton, Vancouver, Winnipeg, Saint John, Greater Sudbury, Hamilton, Kingston, Kitchener
2025-05-28
Active, closed
AstraZeneca
Phase 3
3,103
Surrey, Vancouver, Cambridge, Courtice, Guelph, Hamilton, Mississauga, North York
2025-05-28
Recruiting
McMaster University
Not applicable
120
Hamilton
2025-05-22
Recruiting
Boehringer Ingelheim
Phase 3
4,200
Cambridge, Greater Sudbury, Hamilton, Kitchener, Mississauga, Oakville, Oshawa, Peterborough
2025-05-20
Recruiting
Novartis Pharmaceuticals
Phase 2
224
Edmonton, Hamilton, Markham, Montreal, Verdun
2025-05-16
Recruiting
Perioperative Durvalumab With Neoadjuvant ddMVAC in Patients With Muscle-Invasive Bladder Cancer (NIAGARA-2)
NCT06960577Urinary Bladder Neoplasms, Immune Checkpoint Inhibitors, Methotrexate, Vinblastine
DrugsVinblastine·Methotrexate·Doxorubicin·Durvalumab
AstraZeneca
Phase 2
150
Hamilton, London, Ottawa, Montreal, Québec, Sherbrooke
2025-05-15
Recruiting
World Health Research Inc.
Observational
290
Calgary, Halifax, Hamilton, Newmarket, Ottawa, Toronto, Québec
2025-05-13
Recruiting
Joseph Broderick, MD
Phase 3
350
Calgary, Edmonton, Vancouver, Winnipeg, Hamilton, Ottawa, Toronto, Montreal
2025-05-06
Recruiting
Role of Anti-TREK-1 Autoantibodies in SCVF
NCT06943365Short-coupled Ventricular Fibrillation, Idiopathic Ventricular Fibrillation
Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Observational
300
Vancouver, Hamilton, Ottawa, Québec
2025-05-01
Recruiting
AstraZeneca
Phase 1
72
Hamilton, Sherbrooke
2025-05-01
Active, closed
Merck Sharp & Dohme LLC
Phase 2
440
Hamilton
2025-04-16
Recruiting
McMaster University
Phase 3
134
Hamilton
2025-04-16
Recruiting
A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)
NCT06401330Stage I Mixed Cell Type Kidney Wilms Tumor, Stage II Mixed Cell Type Kidney Wilms Tumor, Stage III Mixed Cell Type Kidney Wilms Tumor, Stage IV Mixed Cell Type Kidney Wilms Tumor
DrugsDactinomycin·Vincrystine·Cytoxan·Paraplatin
Children's Oncology Group
Phase 3
1,656
Calgary, Edmonton, Winnipeg, Halifax, Hamilton, London, Ottawa, Toronto
2025-04-15
Active, closed
Janssen Research & Development, LLC
Phase 3
752
St. John's, Ajax, Barrie, Hamilton, London, Markham, Waterloo, Montreal
2025-04-15
Active, closed
Biomarkers in Patients With Anemia-Induced Thrombocytopenic Bleeding
NCT06947044Acute Leukemia, Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukaemia
Donald Arnold
Not applicable
60
Hamilton
2025-04-11
Recruiting
BeOne Medicines
Phase 3
250
Hamilton, London, Ottawa, Greenfield Park, Montreal, SaintJerome
2025-04-10
Recruiting
Canadian Cancer Trials Group
Phase 3
196
Calgary, Edmonton, Vancouver, Winnipeg, Hamilton, Ottawa, Toronto, Montreal
2025-04-07
Recruiting
Amylyx Pharmaceuticals Inc.
Phase 1
48
Calgary, Hamilton, London, Montreal
2025-04-07
Recruiting
Canadian Cancer Trials Group
Phase 2
128
Abbotsford British Columbia, Surrey, Vancouver, Hamilton, London, Newmarket, Ottawa, Toronto
2025-04-07
Recruiting
Feasibility of a Diet Intervention for Juvenile Arthritis
NCT06474546Arthritis, Juvenile, Arthritis, Childhood, Juvenile Idiopathic Arthritis
The Hospital for Sick Children
Not applicable
54
Winnipeg, Hamilton, London, Ottawa, Toronto, Montreal, Saskatoon
2025-04-07
Recruiting
Gilead Sciences
Phase 3
695
Barrie, Hamilton, Montreal, Rimouski, Toronto
2025-04-04
Recruiting
The Dragon PLC Trial (DRAGON-PLC)
NCT06914648Primary Liver Cancer, Hepatocellular Carcinoma (HCC), Cholangiocarcinoma
Maastricht University
Not applicable
358
Calgary, Vancouver, Halifax, Hamilton, Kingston, London, Toronto, Sherbrooke
2025-04-01
Recruiting
McMaster University
Not applicable
920
Winnipeg, Hamilton, Ottawa, Toronto
2025-04-01
Recruiting
McMaster University
Not applicable
34
Hamilton
2025-04-01
Recruiting
Ontario Clinical Oncology Group (OCOG)
Phase 2
40
Vancouver, Victoria, Hamilton, Kingston, London, Ottawa
2025-03-28
Recruiting
Eli Lilly and Company
Phase 2
200
Brampton, Chicoutimi, Hamilton, Longueuil, Moncton, Sarnia, Toronto, Waterloo
2025-03-28
Recruiting
McMaster University
Phase 2
350
Halifax, Hamilton
2025-03-25
Recruiting
Canadian Critical Care Comparative Effectiveness Platform
NCT06605144Intensive Care Unit ICU, Vasopressor, Platelet, Nutrition
Université de Sherbrooke
Phase 3
5,500
Moncton, Hamilton, Ottawa, Scarborough Village, St. Catharines, Toronto, Longueuil, Montreal
2025-03-23
Recruiting
Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy
NCT06174220Arrhythmogenic Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy
DrugTideglusib
Hamilton Health Sciences Corporation
Phase 2
120
Calgary, Vancouver, Victoria, St. John's, Halifax, Hamilton, Kingston, London
2025-03-21
Active, closed
Psilocybin in the Treatment of Cannabis Use Disorder: A-Proof-of-Concept Study
NCT06225232Cannabis Use Disorder, Moderate, Cannabis Use Disorder, Severe
DrugsPsychotherapy·Psilocybin
McMaster University
Phase 2
16
Hamilton
2025-03-21
Active, closed
Amgen
Phase 3
1,105
Surrey, Winnipeg, Halifax, Brampton, Concord, Hamilton, London, Nepean
2025-03-17
Recruiting
Technology-Enabled Collaborative Care for Diabetes and Mental Health
NCT07181863Type 2 Diabetes, Mental Health, Diabetes Distress
McMaster University
Not applicable
160
Hamilton, Toronto
2025-03-16
Recruiting
Insel Gruppe AG, University Hospital Bern
Phase 4
906
Hamilton
2025-03-14
Active, closed
Amgen
Phase 3
3,853
Surrey, Hamilton, North York, Oshawa, Scarborough Village, Thunder Bay, Toronto, Chicoutimi
2025-03-12
Recruiting
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Phase 3
440
Calgary, Vancouver, Halifax, Hamilton, Montreal
2025-03-12
Active, closed
Exercise-Induced Lactate and Cognitive Function (ExLBC)
NCT06817681Cognition, Sodium Bicarbonate, Lactate, Exercise
McMaster University
Not applicable
32
Hamilton
2025-03-10
Recruiting
Canadian Cancer Trials Group
Phase 3
230
Calgary, Vancouver, Hamilton, Kingston, London, Newmarket, Toronto, Windsor
2025-03-07
Active, closed
Eli Lilly and Company
Phase 3
643
Brampton, Burlington, Courtice, Hamilton, Terrebonne, Thunder Bay, Toronto, Trois-Rivières
2025-03-05
Recruiting
Cohort Network for Adolescents and Youth With multipLe Mental Health Conditions
NCT07699159Multiple Mental Health Conditions, Child Mental Health, Youth Mental Health
Centre for Addiction and Mental Health
Observational
1,620
Calgary, Hamilton, Ottawa, Toronto
2025-03-04
Recruiting
SCORE! ACTIVE Trial
NCT06844786Chronic Disease, Childhood Obesity
Hamilton Health Sciences Corporation
Not applicable
1,400
Hamilton
2025-03-01
Recruiting
AstraZeneca
Phase 3
840
Calgary, Edmonton, Winnipeg, Barrie, Brampton, Hamilton, Toronto, Chicoutimi
2025-03-01
Recruiting
McMaster University
Early Phase 1
20
Hamilton
2025-03-01
By invitation
Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0
NCT06823115Acute Kidney Injury, Fluid Overload, Prematurity Complications, Risk Factors
Indiana University
Observational
8,000
Vancouver, Toronto, Calgary, Edmonton, Hamilton, Montreal
2025-03-01
Not yet open
Β-OHB Supplementation and Brain Health in Older Adults
NCT06588946Subjective Cognitive Decline
McMaster University
Phase 2
48
Hamilton
2025-03
Recruiting
Health Literacy in Geriatric Patients
NCT06971393Health Literacy
Hamilton Health Sciences Corporation
Observational
100
Hamilton
2025-02-26
Recruiting
Kinematic and Mechanical Alignment Randomized Trial
NCT06787417Total Knee Arthroplasty, Osteoarthritis
McMaster University
Phase 4
260
Hamilton
2025-02-20
Active, closed
Novo Nordisk A/S
Phase 3
400
Victoria, Halifax, Hamilton, Québec
2025-02-10
Active, closed
NovoCure GmbH
Phase 3
741
Edmonton, Hamilton, Ottawa, Toronto, Montreal, Sherbrooke
2025-02-03
Recruiting
Sir Mortimer B. Davis - Jewish General Hospital
Observational
4,700
Calgary, Hamilton, Toronto, Montreal, Québec
2025-02-01
Recruiting
Do QT-Prolonging Drugs Cause Major Adverse Cardiac Events in Hospitalized Adults?
NCT07374263Acquired Long QT, Ventricular Arrhythmias, Torsades de Pointes, Syncope
St. Joseph's Healthcare Hamilton
Observational
990,000
Hamilton, Toronto
2025-02-01
Active, closed
Novartis Pharmaceuticals
Phase 3
588
Surrey, St. John's, Hamilton, Richmond Hill, Québec, Saint-Jérôme
2025-01-31
Recruiting
Merck Sharp & Dohme LLC
Phase 3
1,046
Edmonton, Halifax, Hamilton, Oshawa, Toronto
2025-01-27
Recruiting
Incyte Corporation
Phase 3
240
Calgary, Edmonton, Vancouver, Halifax, Hamilton, Toronto, Montreal
2025-01-21
Recruiting
McMaster University
Not applicable
600
Hamilton
2025-01-10
Active, closed
Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis
NCT06846541Plaque Psoriasis, Psoriasis (PsO), Psoriasis, Moderate Psoriasis
Alumis Inc
Phase 3
1,680
Edmonton, Red Deer, Surrey, Ajax, Barrie, Coburg, Guelph, Hamilton
2025-01-08
Recruiting
International Care Bundle Evaluation in Cerebral Hemorrhage Research
NCT06429332Intracerebral Hemorrhage, Intracerebral Haemorrhage, Intraventricular Hemorrhage, Stroke
Region Skane
Phase 4
3,500
Greater Sudbury, Hamilton, Ottawa
2025-01-07
Recruiting
Takeda
Phase 3
396
Calgary, Winnipeg, Halifax, Barrie, Hamilton, Oshawa, Toronto, Vaughan
2025-01-02
Not yet open
Repetitive Transcranial Magnetic Stimulation Paired with Augmented Reality to Alter Concussion Symptoms
NCT06735157Mild Traumatic Brain Injury, Concussion, Chronic Dizziness, Vestibular Problem
McMaster University
Not applicable
40
Hamilton
2025-01-01
Recruiting
Predictors of Relapse in Major Depressive Disorder (PERFORM-D)
NCT06746155Major Depressive Disorder (MDD)
Abraham Nunes
Observational
252
Calgary, Vancouver, Halifax, Hamilton, Kingston, Ottawa, Toronto, Whitby
2024-12-27
Active, closed
Vertex Pharmaceuticals Incorporated
Observational
401
Hamilton, Montreal
2024-12-19
Recruiting
Belimumab in Autoimmune Hepatitis
NCT06381453Autoimmune Hepatitis
DrugBelimumab
University Health Network, Toronto
Phase 2
48
Calgary, Vancouver, Hamilton, London, Ottawa, Toronto
2024-12-11
Recruiting
Canadian Cancer Trials Group
Not applicable
249
Kelowna, Vancouver, Victoria, Hamilton, Toronto, Montreal, Québec, Sherbrooke
2024-12-10
Active, closed
Otsuka Pharmaceutical Development & Commercialization, Inc.
Phase 2
56
Vancouver, Hamilton, Scarborough Village
2024-12-05
Recruiting
Population Health Research Institute
Not applicable
4,500
Winnipeg, Hamilton, Montreal
2024-12-04
Active, closed
AstraZeneca
Phase 3
181
Hamilton, Québec
2024-12-03
Recruiting
Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease
NCT06548399Inflammatory Bowel Diseases, Crohn's Disease, Ulcerative Colitis
McMaster University
Observational
15
Hamilton
2024-12-01
Recruiting
AstraZeneca
Phase 3
1,160
Abbotsford British Columbia, Saint John, Sydney, Greater Sudbury, Hamilton, Kingston, Sault Ste. Marie, Montreal
2024-11-27
Recruiting
Postop Pain Management in Pituitary Tumour Patients
NCT06353529Pituitary, Pain, Postoperative
Hamilton Health Sciences Corporation
Phase 4
108
Hamilton
2024-11-25
Recruiting
McMaster University
Observational
30
Hamilton
2024-11-22
Recruiting
Timing of TAP Blocks in Bariatric Surgery
NCT06270147Opioid Use, Pain, Postoperative
McMaster University
Phase 2
100
Hamilton
2024-11-21
Recruiting
International CRDS Registry
NCT06508164Calcium Release Deficiency Syndrome
Population Health Research Institute
Observational
500
Calgary, Edmonton, Vancouver, Hamilton, London, Ottawa, Montreal, Québec
2024-11-21
Not yet open
SCORE! Non-Physician Health Worker (NPHW) Implementation Protocol (SIP)
NCT06694987Hypertension, Diabetes Mellitus, Dyslipidemia, Metabolic Syndrome
Sonia Anand
Not applicable
137
Hamilton
2024-11-20
Recruiting
Analytical Validation of Stream™ Platform
NCT06541431Gastrointestinal Diseases
FluidAI Medical
Observational
50
Hamilton
2024-11-19
Recruiting
AstraZeneca
Phase 3
1,160
Saint John, Sydney, Greater Sudbury, Hamilton, Sault Ste. Marie, Montreal
2024-11-18
Recruiting
University of Alberta
Not applicable
100
Calgary, Edmonton, St. Albert, Hamilton, North York, Toronto, Regina
2024-11-14
Recruiting
Daptomycin vs. Vancomycin for the Treatment of Methicillin Resistant S. Aureus Bacteremia
NCT06637332Staphylococcus Aureus Septicemia, Staphylococcus Aureus Bacteremia, S. Aureus Bacteremia, S. Aureus Bloodstream Infection
DrugsDaptomycin·Vancomycin
Todd C. Lee MD MPH FIDSA
Phase 4
300
Edmonton, Surrey, St. John's, Hamilton, Toronto, Montreal
2024-11-14
By invitation
Long-term Follow up of the Stability 1 Trial
NCT06885372LET, ACL Reconstruction, Osteoarthritis (OA) of the Knee
Western University, Canada
Not applicable
510
Banff, Calgary, New Westminster, Winnipeg, Hamilton, Kingston, London
2024-11-01
Not yet open
Hamilton Health Sciences Corporation
Phase 2
250
Hamilton
2024-11
Recruiting
A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma
NCT06368817Basal Ganglia Germinoma, Diabetes Insipidus, Germinoma, Pineal Region Germinoma
DrugsParaplatin·Etoposide·Carboplatin
Children's Oncology Group
Phase 2
240
Edmonton, Vancouver, Winnipeg, Halifax, Hamilton, London, Toronto, Montreal
2024-10-22
Recruiting
Merck Sharp & Dohme LLC
Phase 3
680
Halifax, Hamilton, Kingston, Oshawa, Toronto, Montreal, Québec
2024-10-21
Recruiting
Pericardiotomy in Cardiac Surgery
NCT06486636Atrial Fibrillation, Atrial Flutter, Cardiac Events
Population Health Research Institute
Not applicable
1,400
Halifax, Hamilton, Toronto, Montreal
2024-10-21
Recruiting
McMaster University
Not applicable
68
Hamilton, London, Sherbrooke
2024-10-20
Recruiting
DETECTion of PeriOperative Atrial Fibrillation After Noncardiac Surgery
NCT06519747Atrial Fibrillation, Atrial Flutter
Population Health Research Institute
Observational
750
Hamilton, London, St. Catharines, Sherbrooke
2024-10-15
Recruiting
Population Health Research Institute
Not applicable
2,000
Hamilton
2024-10-04
Recruiting
NoNO Inc.
Phase 2
600
Calgary, Edmonton, Vancouver, Winnipeg, Hamilton, Ottawa, Toronto, Saskatoon
2024-10-02
Recruiting
McMaster University
Not applicable
46
Hamilton
2024-10-01
Recruiting
Ferring Pharmaceuticals
Phase 3
454
Calgary, Burlington, Hamilton, Toronto
2024-10-01
Recruiting
Ferring Pharmaceuticals
Phase 3
250
Calgary, Hamilton, Toronto, Montreal
2024-10-01
By invitation
Sanofi
Phase 2
900
Ajax, Hamilton, Sherbrooke, Trois-Rivières
2024-09-30
Recruiting
GlaxoSmithKline
Phase 1
845
Hamilton, Ottawa, Toronto, Montreal, Sherbrooke
2024-09-30
Active, closed
Boehringer Ingelheim
Phase 3
1,666
Edmonton, Kelowna, Vancouver, Moncton, Halifax, Hamilton, Windsor, Montreal
2024-09-26
Active, closed
Nocion Therapeutics
Phase 2
455
Ajax, Burlington, Hamilton, Toronto, Montreal, Québec, Saint-Charles-Borromée, Sherbrooke
2024-09-24
Recruiting
All Providers Better Communication Skills Program' (ABCs)
NCT06606470Education of Primary Care Clinicians, Palliative Care, Communication
McMaster University
Not applicable
350
Hamilton
2024-09-23
Active, closed
McMaster University
Not applicable
170
Hamilton
2024-09-16
Recruiting
Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders
NCT06081348Neurodevelopmental Disorders, Autism, Autism Spectrum Disorder, Fragile X Syndrome
DrugsZoloft·Sertraline
Holland Bloorview Kids Rehabilitation Hospital
Phase 2
130
Calgary, Edmonton, Halifax, Hamilton, Kingston, London, Toronto
2024-09-16
Recruiting
National Cancer Institute (NCI)
Phase 2
153
Calgary, Edmonton, Winnipeg, Halifax, Hamilton, Toronto, Greenfield Park, Montreal
2024-09-13
Recruiting
M3-JIA: Making Mindfulness Matter for Children With JIA
NCT06376149Juvenile Idiopathic Arthritis, Children, Mental Health, Mental Well-being
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Not applicable
74
Hamilton, London, Toronto
2024-09-12
Recruiting
Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas
NCT06422806Metastatic Dedifferentiated Liposarcoma, Metastatic Undifferentiated Pleomorphic Sarcoma, Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8, Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
DrugsDoxorubicin·Keytruda·Pembrolizumab
National Cancer Institute (NCI)
Phase 3
365
Calgary, Edmonton, Vancouver, Winnipeg, Hamilton, Ottawa, Toronto, Québec
2024-09-11
Recruiting
Regeneron Pharmaceuticals
Phase 1/2
130
Edmonton, Hamilton, Montreal
2024-09-11
Active, closed
Alpine Immune Sciences Inc, A Subsidiary of Vertex
Phase 3
605
Hamilton
2024-08-30
Recruiting
AIRE-2 Device for Study of Breath Analysis in IBD
NCT06541938Inflammatory Bowel Diseases
McMaster University
Not applicable
60
Hamilton
2024-08-28
Active, closed
AbbVie
Phase 3
699
Calgary, Edmonton, Vancouver, Halifax, Hamilton, Markham, Niagara Falls, Toronto
2024-08-19
Recruiting
AstraZeneca
Phase 3
1,018
Winnipeg, Halifax, Barrie, Hamilton, Oshawa, Toronto, Chicoutimi, Montreal
2024-08-07
Active, closed
Merck Sharp & Dohme LLC
Phase 3
686
Kelowna, Surrey, Victoria, Barrie, Hamilton, Montreal, Québec
2024-07-24
Active, closed
Celldex Therapeutics
Phase 3
976
Edmonton, Hamilton, London, North Bay, Ottawa, Richmond Hill, Toronto, Windsor
2024-07-19
Recruiting
GlaxoSmithKline
Phase 3
150
Ajax, Hamilton, London
2024-07-19
Recruiting
Ottawa Hospital Research Institute
Not applicable
420
Hamilton, Kingston, Ottawa, Toronto, Québec, Saskatoon
2024-07-16
Active, closed
Celldex Therapeutics
Phase 3
963
Edmonton, St. John's, Hamilton, Markham, Richmond Hill, Toronto, Calgary
2024-07-11
Recruiting
Precision Dosing of Oral Ibuprofen for PDA, A Pilot RCT
NCT07143201Patent Ductus Arteriosus, Preterm
Hamilton Health Sciences Corporation
Phase 2
26
Hamilton
2024-07-04
Recruiting
Affect of Duavive on Mood & Anxiety Symptoms
NCT04478305Menopause, Depression, Anxiety, Sleep, Menopause Related Conditions
St. Joseph's Healthcare Hamilton
Phase 1
30
Hamilton
2024-07-03
Active, closed
Novartis Pharmaceuticals
Phase 2
155
Hamilton, Toronto, Rimouski, Trois-Rivières
2024-07-02
Active, closed
AstraZeneca
Phase 3
339
Vancouver, Hamilton, Toronto
2024-06-29
Active, closed
AbbVie
Phase 3
1,400
Calgary, Edmonton, Kelowna, Fredericton, St. John's, Cobourg, Hamilton, London
2024-06-27
Recruiting
Merck Sharp & Dohme LLC
Phase 3
1,530
Calgary, Edmonton, Vancouver, Winnipeg, Moncton, Halifax, Hamilton, Kingston
2024-06-24
Active, closed
McMaster University
Not applicable
3,060
Hamilton
2024-06-19
Recruiting
Alimentiv Inc.
Observational
50
Hamilton, London
2024-06-19
Recruiting
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
NCT05564390Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy, Acute Myeloid Leukemia, Myelodysplasia-Related
DrugsEmavusertib·Olutasidenib·Vyxeos·Mylotarg
National Cancer Institute (NCI)
Phase 2
2,000
Calgary, Edmonton, Winnipeg, Halifax, Hamilton, Ottawa, Toronto, Greenfield Park
2024-06-18
Recruiting
Boehringer Ingelheim
Phase 3
6,712
Cambridge, Hamilton, Mississauga, Oakville, Oshawa, Peterborough, Sarnia, Stoney Creek
2024-06-17
Recruiting
Population Health Research Institute
Phase 3
400
Hamilton, Toronto
2024-06-13
Recruiting
LEO Pharma
Phase 3
195
Burlington, Calgary, Edmonton, Hamilton, Niagara Falls, Saskatoon, Windsor, Winnipeg
2024-06-10
Recruiting
Eli Lilly and Company
Phase 3
300
Hamilton, Sarnia
2024-06-03
Recruiting
Merck Sharp & Dohme LLC
Phase 3
348
Winnipeg, Halifax, Hamilton, Toronto, Montreal, Trois-Rivières
2024-05-24
Active, closed
Albumin Utilization in Adult Cardiac Surgical Patients: Retrospective
NCT06322537Cardiovascular Surgical Procedures, Albumin
University Health Network, Toronto
Observational
505
New Westminster, Vancouver, Halifax, Hamilton, Kingston, London, Ottawa, Toronto
2024-05-23
Recruiting
Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer
NCT06343402Non-small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer, NSCLC, KRAS G12C
DrugsBBO-10203·Pembrolizumab
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)
Phase 1
350
Edmonton, Hamilton, Toronto, Montreal
2024-05-22
Recruiting
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
NCT06237452Clostridium Difficile, Clostridium Difficile Infections, Clostridium Difficile Infection Recurrence, Clostridioides Difficile Infection
Vedanta Biosciences, Inc.
Phase 3
852
Calgary, Edmonton, Red Deer, Vancouver, Moncton, St. John's, Hamilton, London
2024-05-20
Recruiting
Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia
NCT04886284Staphylococcus Aureus Bacteremia, Staphylococcus Aureus Septicemia, Staphylococcal Sepsis, Staphylococcus Aureus Endocarditis
DrugErtapenem
Todd C. Lee MD MPH FIDSA
Phase 2
60
Calgary, Surrey, Hamilton, Ottawa, Saint Catharines, Laval, Montreal
2024-05-20
Active, closed
Alnylam Pharmaceuticals
Phase 2
210
Calgary, Hamilton, Kelowna, Moncton, Montreal, Ottawa, Toronto, Victoria
2024-05-17
Recruiting
Equilibra Bioscience LLC
Phase 1
31
Hamilton
2024-05-10
Recruiting
Hamilton Health Sciences Corporation
Phase 3
21,006
Hamilton
2024-05-07
Recruiting
Intra-articular Corticosteroid With Hyaluronic Acid Plus Physiotherapy for Hip Pathologies (NON-OP HIP)
NCT06653985Osteoarthritis, Femoroacetabular Impingement Syndrome, Labrum Injury of the Hip Joint
ArthroBiologix Inc.
Not applicable
100
Hamilton
2024-05-01
Recruiting
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
NCT06164730Heterozygous Familial Hypercholesterolemia, Premature Coronary Heart Disease
DrugVERVE-102
Verve Therapeutics, Inc.
Phase 1
85
Chicoutimi, Hamilton, Montreal, Québec, Toronto, Vancouver
2024-04-30
Recruiting
CSL Behring
Phase 2/3
3,110
Edmonton, Halifax, Hamilton, Kingston, London, Oshawa, Montreal, Longueuil
2024-04-27
Recruiting
RAFT - Pace &Ablate
NCT06299514Atrial Fibrillation, Heart Failure, Pacemaker, Arrhythmia Atrial
Habib Khan
Not applicable
600
Victoria, Halifax, Hamilton, Kitchener, London, Newmarket, Ottawa, Toronto
2024-04-25
Recruiting
National Cancer Institute (NCI)
Phase 3
478
Calgary, Edmonton, Vancouver, Winnipeg, St. John's, Halifax, Hamilton, London
2024-04-19
Recruiting
Jeffrey Pernica
Not applicable
75
Hamilton
2024-04-17
Active, closed
A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.
NCT06372145Relapsing Multiple Sclerosis, Secondary Progressive Multiple Sclerosis, Progressive Relapsing Multiple Sclerosis
DrugTeriflunomide
Sanofi
Phase 3
2,500
Edmonton, Burnaby, Vancouver, Halifax, Hamilton, Ottawa, Toronto, Gatineau
2024-04-16
Recruiting
Canadian Cancer Trials Group
Phase 2
168
Calgary, Vancouver, Winnipeg, Halifax, Barrie, Hamilton, Kingston, Kitchener
2024-04-16
Recruiting
AstraZeneca
Phase 3
3,850
New Westminster, North Vancouver, Vancouver, Winnipeg, Sydney, Cambridge, Hamilton, London
2024-04-12
Active, closed
A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
NCT06329401Pulmonary Fibrosis, Progressive Pulmonary Fibrosis, Pulmonary Fibrosis Secondary to Systemic Sclerosis, Pulmonary Fibrosis, Interstitial Lung Disease
DrugPirfenidone
Avalyn Pharma Inc.
Phase 2
398
Vancouver, Ajax, Hamilton, Montreal, Québec, Trois-Rivières
2024-04-03
Active, closed
[Ac-225]-PSMA-62 Trial in Oligometastatic Hormone Sensitive and Metastatic Castration Resistant Prostate Cancer
NCT06229366Prostate Cancer, Metastatic Castration-resistant Prostate Cancer, Oligometastatic Prostate Carcinoma, Hormone Sensitive Prostate Cancer
Eli Lilly and Company
Phase 1
142
Hamilton, Montreal, Québec, Saguenay, Toronto, Vancouver
2024-04-03
Recruiting
A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis
NCT05828069Recurrent Langerhans Cell Histiocytosis, Refractory Langerhans Cell Histiocytosis
DrugTovorafenib
National Cancer Institute (NCI)
Phase 2
48
Edmonton, Vancouver, Halifax, Hamilton, London, Toronto, Montreal, Sherbrooke
2024-03-28
Recruiting
GlaxoSmithKline
Phase 3
864
Greater Sudbury, Hamilton, Toronto, Montreal
2024-03-21
Recruiting
McMaster University
Phase 2
129
Burlington, Hamilton, St. Catharines
2024-03-15
Recruiting
Ontario Clinical Oncology Group (OCOG)
Observational
352
Prince George, Barrie, Hamilton, Kingston, Thunder Bay, Toronto, Montreal, Québec
2024-03-12
Recruiting
McMaster Children's Hospital
Phase 1
20
Hamilton, Toronto
2024-03-11
Recruiting
First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC)
NCT06217822Advanced Metastatic Castration-resistant Prostate Cancer, Prostate Specific Membrane Antigen (PSMA) Expression
Bayer
Phase 1
198
Edmonton, Vancouver, Hamilton, Toronto, Montreal, Sherbrooke
2024-03-07
Active, closed
Eli Lilly and Company
Phase 3
17,300
Brampton, Chicoutimi, Hamilton, Joliette, London, Longueuil, Moncton, New Westminster
2024-03-05
Recruiting
The STOP-MED CTRCD Trial
NCT06183437Heart Failure, Cardiotoxicity, Cardiac Toxicity, Antineoplastics Toxicity
Dinesh Thavendiranathan
Phase 4
335
Edmonton, Winnipeg, Hamilton, Ottawa, Toronto
2024-03-04
Not yet open
Outcomes of Children After Hospitalization in Intensive Care Unit
NCT06124092Renal Disease, Liver Diseases, Heart Diseases, Trauma Injury
St. Justine's Hospital
Observational
690
Calgary, Vancouver, Hamilton, Ottawa, Toronto, Montreal, Sherbrooke
2024-03
Active, closed
Sanofi
Phase 3
464
Calgary, Edmonton, Burlington, Hamilton, London, Toronto, Québec, Regina
2024-02-29
Active, closed
Eli Lilly and Company
Phase 3
1,250
Calgary, Edmonton, Brampton, Hamilton, Sarnia, Toronto, Whitby, Montreal
2024-02-21
Recruiting
St. Justine's Hospital
Observational
3,000
Calgary, Edmonton, Vancouver, Halifax, Hamilton, Kingston, London, Oshawa
2024-02-13
Recruiting
Canadian Cancer Trials Group
Phase 2
30
Calgary, Vancouver, Hamilton, Ottawa, Toronto, Montreal, Québec, Regina
2024-02-13
Not yet open
Hamilton Health Sciences Corporation
Phase 1
29
Hamilton
2024-02
Recruiting
CSL Behring
Phase 3
35
Hamilton
2024-01-30
Active, closed
Incyte Corporation
Phase 3
617
Calgary, Edmonton, Surrey, Winnipeg, Fredericton, Barrie, Hamilton, London
2024-01-30
Recruiting
Hamilton Health Sciences Corporation
Phase 3
2,500
Hamilton
2024-01-29
Active, closed
Janssen Research & Development, LLC
Phase 3
838
Calgary, Vancouver, Halifax, Hamilton, Toronto, Montreal, Saskatoon
2024-01-22
Active, closed
Regeneron Pharmaceuticals
Observational
11
Hamilton, Montreal
2024-01-17
Active, closed
Janssen Research & Development, LLC
Phase 3
774
Surrey, St. John's, Ajax, Barrie, Hamilton, Richmond Hill, Waterloo, Windsor
2024-01-17
Active, closed
PeRiopEratiVE SmokiNg CessaTion Trial
NCT05102123Smoking (Tobacco) Addiction, Smoking Cessation
DrugCytisine
Population Health Research Institute
Phase 3
1,720
Hamilton, Kingston, London
2024-01-15
Active, closed
The Pharmacokinetics of Single Dose Oral Tetrahydrocannabinol and Cannabidiol
NCT05742724Cannabis, Chronic Kidney Diseases, Dialysis
McMaster University
Phase 1
24
Hamilton
2024-01-11
Active, closed
A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia
NCT05761171Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged
DrugsHydrocortisone Sodium Succinate·Revumenib·Fludarabine Phosphate·Calaspargase Pegol
Children's Oncology Group
Phase 2
78
Vancouver, Winnipeg, Halifax, Hamilton, London, Ottawa, Toronto, Montreal
2024-01-08
By invitation
Sanofi
Phase 3
90
Edmonton, Vancouver, Burlington, Hamilton, Montreal, Sherbrooke
2024-01-03
Recruiting
Emergency Medicine Pulmonary Embolism Testing Multicentre Study
NCT06320236Pulmonary Embolism, D-dimer, Diagnosis
Dr. Kerstin de Wit
Observational
4,000
Hamilton, Kingston, London, Ottawa
2024-01-01
Active, closed
Boston Scientific Corporation
Not applicable
484
Hamilton, Québec
2023-12-28
Active, closed
Trial of Efficacy and Safety of NS-229 Versus Placebo in Patients With Eosinophilic Granulomatosis With Polyangiitis
NCT06046222Eosinophilic Granulomatosis With Polyangiitis, Churg-Strauss Syndrome
NS Pharma, Inc.
Phase 2
45
Edmonton, Hamilton, Toronto
2023-12-20
Active, closed
AbbVie
Phase 3
614
Calgary, Surrey, Winnipeg, Fredericton, Hamilton, Waterloo, Québec, Saint-Jérôme
2023-12-19
Active, closed
Deciphera Pharmaceuticals, LLC
Phase 3
54
Calgary, Hamilton, Toronto, Montreal
2023-12-13
Active, closed
Novartis Pharmaceuticals
Phase 3
362
Winnipeg, Hamilton, Trois-Rivières
2023-12-07
Active, closed
Economic Evaluation of Stream™ Platform
NCT05994625Anastomotic Leak
FluidAI Medical
Phase 3
215
Hamilton
2023-12-06
Recruiting
AstraZeneca
Phase 1/2
226
Hamilton, Ottawa, Toronto, Montreal, Nova Scotia
2023-12-05
Recruiting
Akero Therapeutics, Inc
Phase 3
1,650
Edmonton, Hamilton, Toronto, Vaughan, Montreal, Terrebonne
2023-12-01
Recruiting
The Fourth Left Atrial Appendage Occlusion Study
NCT05963698Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism
Hamilton Health Sciences Corporation
Not applicable
4,000
Calgary, Vancouver, Winnipeg, Burlington, Cambridge, Hamilton, Kitchener, London
2023-11-30
Active, closed
St. Joseph's Healthcare Hamilton
Not applicable
20
Brantford, Hamilton
2023-11-30
Recruiting
AstraZeneca
Phase 3
625
Barrie, Hamilton, Toronto, Greenfield Park, Montreal, Québec, Regina, Saskatoon
2023-11-23
Recruiting
Edwards Lifesciences
Not applicable
200
Vancouver, Hamilton, Québec
2023-11-22
Recruiting
A Randomized Trial of Five Fraction Partial Breast Irradiation (RAPID2)
NCT05417516Breast Neoplasm Female, Radiotherapy, Cosmetic Outcome
Ontario Clinical Oncology Group (OCOG)
Phase 3
910
Calgary, Victoria, Halifax, Barrie, Hamilton, London, Newmarket, Sault Ste. Marie
2023-11-20
By invitation
Combining Ultrasound and Biomarkers to Diagnose Superficial Endometriosis
NCT05523284Endometriosis (Diagnosis), Endometriosis
McMaster University
Observational
50
Hamilton
2023-11-15
Active, closed
Novartis Pharmaceuticals
Phase 3
470
Edmonton, Hamilton, London, Niagara Falls, Québec, Verdun
2023-11-15
Active, closed
Akero Therapeutics, Inc
Phase 3
700
Edmonton, Hamilton, Toronto, Vaughan, Terrebonne
2023-11-10
Active, closed
Bristol-Myers Squibb
Phase 2
227
Hamilton, Toronto
2023-11-07
Recruiting
University of Maryland, Baltimore
Phase 3
312
New Westminster, Vancouver, Hamilton, London, Ottawa
2023-11-05
Recruiting
Tanja Andrea Gruber
Phase 1/2
90
Calgary, Edmonton, Vancouver, Hamilton, Montreal, Québec
2023-11-03
Recruiting
Albumin To Enhance Recovery After Acute Kidney Injury
NCT04705896Acute Kidney Injury, Renal Replacement Therapy, Hypotension, Critical Illness
Ottawa Hospital Research Institute
Phase 4
856
Calgary, Winnipeg, Halifax, Hamilton, Kingston, North York, Ottawa, Scarborough Village
2023-11-02
Recruiting
Thresholds In Food Allergy evaluaTion And predictioN
NCT06038019Tree Nut Allergy, Food Allergy
Hamilton Health Sciences Corporation
Observational
2,000
Hamilton
2023-11-01
Recruiting
Epineuron Technologies Inc.
Not applicable
26
Hamilton
2023-11-01
Active, closed
Minimally Displaced Femoral Neck Fracture Pilot Study
NCT05947058Femoral Neck Fractures
University of Maryland, Baltimore
Not applicable
40
Vancouver, Hamilton, London
2023-11-01
Recruiting
United Therapeutics
Phase 3
698
Vancouver, Ajax, Hamilton, Montreal, Québec, Sherbrooke, Saskatoon
2023-10-30
Active, closed
Bristol-Myers Squibb
Phase 3
1,057
Sherwood Park, Kelowna, Vancouver, Burlington, Hamilton, Owen Sound, Toronto, Montreal
2023-10-25
Recruiting
University of Calgary
Phase 4
210
Calgary, Edmonton, Vancouver, Halifax, Brampton, Brantford, Hamilton, London
2023-10-25
Active, closed
McMaster University
Not applicable
114
Hamilton
2023-10-17
Recruiting
An Innovative Master Platform for Clinical Trials in Mood Disorders
NCT06408012Mood Disorders, Depressive Disorder, Bipolar and Related Disorders
St. Joseph's Healthcare Hamilton
Observational
2,200
Calgary, Vancouver, Halifax, Hamilton, Kingston, Ottawa, Toronto, Whitby
2023-10-17
Active, closed
Celgene
Phase 3
79
Edmonton, Hamilton, Montreal
2023-10-16
Active, closed
Eli Lilly and Company
Phase 3
160
Edmonton, Hamilton, Toronto, Chicoutimi
2023-10-16
Recruiting
University of British Columbia
Phase 3
360
Vancouver, Hamilton, Kingston, Toronto, Montreal
2023-10-15
Recruiting
AbbVie
Phase 3
1,500
Calgary, Edmonton, Surrey, Winnipeg, Barrie, Greater Sudbury, Hamilton, Markham
2023-10-11
Active, closed
Stichting European Myeloma Network
Phase 3
759
Edmonton, Hamilton, Montreal, Ottawa, Québec, Toronto, Vancouver
2023-10-10
Recruiting
Advancing Brain Outcomes in Pediatric Critically Ill Patients Sedated With Volatile AnEsthestic Agents
NCT05867472Intensive Care Units, Pediatric, Anesthetics, Inhalation, Mechanically Ventilated, Critically Ill Children
DrugIsoflurane Inhalant Product
Sunnybrook Health Sciences Centre
Phase 3
60
Hamilton, London, Toronto
2023-10-10
Recruiting
Hamilton Health Sciences Corporation
Observational
58
Hamilton
2023-10-01
Recruiting
D3-Creatine and Skeletal Muscle in Older Adults
NCT06630949Aging, Muscle Loss
McMaster University
Observational
350
Hamilton
2023-10-01
Recruiting
Healthy Outcomes for Muscle with Exercise in T1D
NCT05740514Diabetes Mellitus, Type 1
McMaster University
Not applicable
168
Hamilton
2023-10-01
Active, closed
AstraZeneca
Phase 1/2
166
Surrey, Hamilton, Sarnia, Stouffville, Toronto, Sherbrooke
2023-09-29
Recruiting
AstraZeneca
Phase 3
800
Hamilton, London, Toronto, Montreal, Ste-Foy
2023-09-22
Recruiting
Hoffmann-La Roche
Phase 1/2
60
Vancouver, Hamilton
2023-09-21
Active, closed
Bristol-Myers Squibb
Phase 3
1,255
Sherwood Park, Kelowna, Vancouver, Burlington, Hamilton, Owen Sound, Toronto, Greenfield Park
2023-09-14
Active, closed
Hoffmann-La Roche
Phase 3
687
Hamilton, Toronto, Montreal
2023-09-14
Recruiting
Left vs Left Randomized Clinical Trial
NCT05650658Heart Failure, Heart Failure With Reduced Ejection Fraction, AV Block, LBBB
Baylor College of Medicine
Not applicable
2,136
Edmonton, Vancouver, Victoria, Halifax, Hamilton, Newmarket, Ottawa, Toronto
2023-09-13
Active, closed
Implementation of P-INPAC
NCT06645639Malnutrition, Child, Nutrition Poor
The Hospital for Sick Children
Observational
600
Hamilton, Toronto, Montreal
2023-09-04
Recruiting
Hamilton Health Sciences Corporation
Not applicable
60
Hamilton
2023-09-01
Active, closed
Teva Branded Pharmaceutical Products R&D LLC
Phase 3
2,769
Edmonton, Ajax, Etobicoke, Hamilton, Winchester, Windsor
2023-08-30
Recruiting
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Phase 3
500
Calgary, Hamilton, Toronto, Whitby, Montreal, Verdun
2023-08-28
Recruiting
AstraZeneca
Phase 3
231
Edmonton, Burlington, Hamilton, Windsor, Montreal
2023-08-24
Active, closed
Pfizer
Phase 2
507
Winnipeg, Greater Sudbury, Hamilton, Mississauga, Toronto, Chicoutimi, Québec
2023-08-22
By invitation
McMaster University
Not applicable
24
Hamilton
2023-08-22
Recruiting
Dr. Stephanie Sibley
Phase 4
200
Hamilton, Kingston, Ottawa
2023-08-20
Recruiting
Epineuron Technologies Inc.
Not applicable
110
Edmonton, Saint John, Hamilton, London, Newmarket, Toronto
2023-08-11
Recruiting
St. Joseph's Healthcare Hamilton
Observational
100
Hamilton
2023-08-11
Recruiting
The Hospital for Sick Children
Not applicable
93
Halifax, Hamilton, London, Ottawa, Toronto, Montreal, Saskatoon, Calgary
2023-08-05
Active, closed
Sunnybrook Health Sciences Centre
Phase 2
115
Hamilton, London, Ottawa, Toronto
2023-08-01
Recruiting
A Study of Reduced Dosing of the Nonavalent HPV Vaccine in Women Living With HIV
NCT05495906HPV, Human Papilloma Virus, Human Immunodeficiency Virus
DrugNonavalent HPV vaccine
University of British Columbia
Phase 4
275
Surrey, Vancouver, Winnipeg, Hamilton, Toronto, Montreal, Québec, Regina
2023-07-27
Recruiting
RCT Evaluating First Time Shoulder Dislocation
NCT05715021Shoulder Dislocation, Sport Injury, Anterior Dislocation
McMaster University
Not applicable
100
Hamilton
2023-07-12
Recruiting
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Phase 3
1,000
Calgary, Hamilton, Whitby, Montreal, Verdun
2023-07-11
By invitation
A Study to Provide Access to Mitapivat for Participants Who Previously Participated in an Agios-Sponsored Mitapivat Study
NCT05777993Pyruvate Kinase Deficiency, Anemia, Hemolytic, Sickle Cell Disease, Thalassemia
DrugMitapivat
Agios Pharmaceuticals, Inc.
Phase 4
55
Hamilton, Toronto
2023-07-06
Active, closed
Population Health Research Institute
Not applicable
5,100
Montreal, Brampton, Edmonton, Hamilton, Kingston, Kitchener, London, Newmarket
2023-06-22
Recruiting
The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C)
NCT05427370Coronary Artery Disease, Heart Failure Systolic
Sunnybrook Health Sciences Centre
Not applicable
754
Calgary, Edmonton, New Westminster, Vancouver, Winnipeg, Halifax, Hamilton, London
2023-06-22
Active, closed
AbbVie
Phase 3
1,328
Calgary, Edmonton, Red Deer, Surrey, Winnipeg, St. John's, Hamilton, London
2023-06-21
Recruiting
Frailty Assessments for Risk Assessment in Gynecologic Oncology Patients
NCT05738252Gynecologic Cancer, Frailty, Oncology
Population Health Research Institute
Observational
280
Hamilton, Mississauga, Toronto
2023-06-15
Recruiting
Canadian Cancer Trials Group
Phase 2
484
Calgary, Kelowna, Vancouver, Halifax, Hamilton, Kingston, Ottawa, Toronto
2023-06-13
Active, closed
McMaster University
Observational
90
Hamilton
2023-06-10
Active, closed
AbbVie
Observational
1,019
Calgary, Edmonton, Lethbridge, Kelowna, New Westminster, Victoria, Moncton, Hamilton
2023-06-09
Recruiting
Hoffmann-La Roche
Phase 3
420
Calgary, Edmonton, Vancouver, Moncton, Hamilton, Ottawa, Montreal
2023-06-07
Recruiting
Conjupro Biotherapeutics, Inc.
Phase 1
132
Edmonton, Hamilton, Toronto
2023-06-06
Recruiting
Jonathan Troy Grennan
Not applicable
560
Calgary, Vancouver, Hamilton, Ottawa, Toronto, Montreal
2023-06-02
Recruiting
Surgical Ablation of AF Efficacy Trial
NCT05434819Atrial Fibrillation, Heart Failure
Population Health Research Institute
Not applicable
2,000
Hamilton
2023-06-01
Recruiting
University of Manitoba
Phase 2
80
Calgary, Edmonton, Winnipeg, Hamilton, Kingston, Ottawa, Toronto, Montreal
2023-06-01
Recruiting
National Cancer Institute (NCI)
Phase 3
1,875
Calgary, Edmonton, Vancouver, Winnipeg, Halifax, Hamilton, London, Ottawa
2023-05-11
Active, closed
McMaster University
Phase 4
446
Calgary, New Westminster, Vancouver, Hamilton, London, Ottawa, Toronto, Montreal
2023-05-01
Recruiting
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
NCT04124120Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting
Weill Medical College of Cornell University
Not applicable
2,300
Edmonton, Winnipeg, Saint John, St. John's, Greater Sudbury, Hamilton, London, Ottawa
2023-04-17
Recruiting
University of Calgary
Observational
825
Calgary, Edmonton, Vancouver, Winnipeg, Hamilton, Ottawa, Toronto, Montreal
2023-04-04
Active, closed
Bayer
Phase 3
985
Calgary, Edmonton, Abbotsford British Columbia, Vancouver, Victoria, Halifax, Hamilton, London
2023-04-03
Active, closed
Janssen Research & Development, LLC
Phase 3
1,135
Halifax, Hamilton, Toronto, Montreal, Québec, Saint Jerome Quebec
2023-03-23
Recruiting
AbbVie
Phase 1
210
Hamilton, Ottawa
2023-03-21
Recruiting
Anthony Bai
Not applicable
700
Hamilton, Kingston, Montreal
2023-03-20
Recruiting
Stanford University
Not applicable
200
Hamilton
2023-03-17
Active, closed
Merck Sharp & Dohme LLC
Phase 3
641
Hamilton, Toronto, Montreal
2023-03-17
Recruiting
Vega Therapeutics, Inc
Phase 1/2
116
Hamilton, Kingston, Toronto
2023-03-16
Active, closed
AbbVie
Phase 3
520
Calgary, Edmonton, Surrey, Vancouver, Hamilton, Kingston, Ottawa, Toronto
2023-03-15
Recruiting
AMIC Compared With Microfracture for Focal Articular Cartilage Damage of the Hip
NCT05402072Hip Arthroscopy, Articular Cartilage Defect, Microfractures
McMaster University
Phase 1
40
Hamilton
2023-03-13
Active, closed
Merck Sharp & Dohme LLC
Phase 3
537
Hamilton, Toronto, Montreal, Regina
2023-03-08
Active, closed
Bristol-Myers Squibb
Phase 3
579
Calgary, Hamilton, Ottawa, Toronto, Québec
2023-03-06
Active, closed
Novo Nordisk A/S
Phase 3
7,101
Calgary, Moncton, Halifax, Barrie, Brampton, Cambridge, Hamilton, Toronto
2023-03-01
Recruiting
Longitudinal Study for Central Nervous System Vasculitis
NCT05734404Central Nervous System Vasculitis, CNS Vasculitis, CNSV, Vasculitis
University of Pennsylvania
Observational
40
Hamilton, Toronto
2023-03-01
Active, closed
AstraZeneca
Observational
551
Calgary, Winnipeg, Hamilton, Orillia, Toronto, Rimouski, Sherbrooke, Ste-Foy
2023-02-27
Active, closed
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
NCT05566795Low-grade Glioma, Rapidly Accelerated Fibrosarcoma (RAF) Altered Glioma, Pediatric Low-grade Glioma
DrugsTovorafenib·Carboplatin
Day One Biopharmaceuticals, Inc.
Phase 3
418
Calgary, Edmonton, Vancouver, Hamilton, London, Ottawa, Montreal, Québec
2023-02-27
Recruiting
McMaster University
Not applicable
1,750
Hamilton, Toronto, Montreal, Québec
2023-02-22
Active, closed
Merck Sharp & Dohme LLC
Phase 3
553
Hamilton, Toronto, Montreal
2023-02-20
Active, closed
A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A
NCT05685238Haemophilia A, Haemophilia A With Inhibitors
Novo Nordisk A/S
Phase 3
451
Hamilton, Toronto
2023-02-13
Recruiting
Canadian Cancer Trials Group
Phase 3
510
Vancouver, Winnipeg, Greater Sudbury, Hamilton, Toronto, Montreal, Sherbrooke
2023-02-10
Active, closed
Genmab
Phase 3
900
Calgary, Vancouver, Brampton, Hamilton, Saskatoon
2023-02-08
Recruiting
Dopamine vs. Norepinephrine for Hypotension in Very Preterm Infants With Late-onset Sepsis
NCT05347238Late-Onset Neonatal Sepsis, Extreme Prematurity, Neonatal Hypotension
DrugsDopamine·Norepinephrine
Mount Sinai Hospital, Canada
Observational
550
Calgary, Vancouver, Victoria, Winnipeg, Halifax, Hamilton, London, Ottawa
2023-02-06
Recruiting
Evaluation of A Clinical Diagnostic Test for CRDS
NCT06188689Calcium Release Deficiency Syndrome (CRDS)
Population Health Research Institute
Not applicable
400
Calgary, Edmonton, Vancouver, Hamilton, London, Ottawa, Toronto, Montreal
2023-02-02
Active, closed
Sanofi
Phase 3
91
Hamilton, Toronto
2023-02-01
Recruiting
NSCLC Liquid Biopsies and Exhaled VOC
NCT06707519Lung Cancer, Circulating Tumor DNA
St. Joseph's Healthcare Hamilton
Observational
210
Hamilton
2023-02-01
Active, closed
Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial
NCT05478304Ischemic Stroke, Systemic Embolism
AtriCure, Inc.
Not applicable
6,573
Calgary, Edmonton, New Westminster, Saint John, Halifax, Hamilton, Kingston, London
2023-01-25
Recruiting
Population Health Research Institute
Not applicable
891
Hamilton, Thunder Bay, Toronto
2023-01-23
Recruiting
Nova Scotia Health Authority
Phase 4
400
Calgary, Vancouver, Halifax, Hamilton, Kingston, Ottawa, Toronto, Whitby
2023-01-20
Recruiting
McMaster University
Phase 1
36
Hamilton
2023-01-17
Recruiting
University of Manitoba
Not applicable
90
Calgary, Winnipeg, Hamilton
2023-01-14
Active, closed
Bristol-Myers Squibb
Phase 3
516
Calgary, Hamilton, London, Toronto, Rimouski
2023-01-12
Active, closed
Sunnybrook Health Sciences Centre
Not applicable
166
Hamilton, Kingston, London, Ottawa, Toronto
2023-01-06
Recruiting
Canadian Cancer Trials Group
Phase 2
393
Calgary, Edmonton, Kelowna, Prince George, Vancouver, Victoria, Barrie, Hamilton
2022-12-19
Recruiting
Mount Sinai Hospital, Canada
Phase 2
310
Edmonton, Hamilton, Toronto, Québec
2022-12-12
Recruiting
Pfizer
Phase 3
100
Edmonton, Hamilton
2022-12-09
Active, closed
Bellus Health Inc. - a GSK company
Phase 3
997
Calgary, Ajax, Hamilton, Toronto, Windsor, Montreal, Québec, Saint-Charles-Borromée
2022-12-05
Recruiting
Synapse 3D With Intravascular Indocyanine Green
NCT03953144Non-small Cell Lung Cancer, Primary Neoplasm
DrugIC-Green
St. Joseph's Healthcare Hamilton
Phase 1/2
32
Hamilton
2022-12-01
Recruiting
Tryptophan for Impaired AhR Signaling in Celiac Disease
NCT05576038Tryptophan Metabolism Alterations, Celiac Disease
McMaster University
Not applicable
50
Hamilton
2022-12-01
Recruiting
McMaster University
Observational
45
Hamilton
2022-11-29
Active, closed
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
NCT05476926Neovascular Age-related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion, Branch Retinal Vein Occlusion
DrugsVabysmo·Faricimab
Hoffmann-La Roche
Observational
6,000
New Westminster, Don Mills, Hamilton, London, Ottawa, Vaughan, Boisbriand, Montreal
2022-11-21
Active, closed
Dazucorilant in Patients With Amyotrophic Lateral Sclerosis
NCT05407324Amyotrophic Lateral Sclerosis
Corcept Therapeutics
Phase 2
279
Hamilton, Montreal
2022-11-15
By invitation
University Health Network, Toronto
Not applicable
580
Hamilton, Toronto
2022-11-15
Active, closed
AstraZeneca
Phase 3
368
Hamilton, London, Niagara Falls, Ottawa, Windsor
2022-11-10
Recruiting
Canadian Cancer Trials Group
Phase 2
84
Calgary, Vancouver, St. John's, Halifax, Hamilton, London, Ottawa, Toronto
2022-11-01
Active, closed
Novo Nordisk A/S
Phase 3
3,400
Edmonton, Sherwood Park, Surrey, Victoria, Moncton, Halifax, Hamilton
2022-11-01
Active, closed
PharmaEssentia
Phase 3
111
Calgary, Vancouver, Hamilton, Ottawa, Toronto
2022-10-26
Active, closed
Eli Lilly and Company
Phase 3
15,374
Brampton, Calgary, Chicoutimi, Courtice, Greater Sudbury, Halifax, Hamilton, Lévis
2022-10-11
Active, closed
Clinical Trial on Agitation in Alzheimer's Dementia
NCT05543681Alzheimer Disease, Agitation,Psychomotor, Care Giving Burden, NPS
IGC Pharma, LLC
Phase 2
164
Victoria, Hamilton, Toronto, Montreal
2022-10-11
Recruiting
Ottawa Hospital Research Institute
Phase 3
1,828
Halifax, Brampton, Hamilton, Ottawa, Sault Ste. Marie, St. Catharines, Windsor, Greenfield Park
2022-10-05
Recruiting
Kirsten Bell
Not applicable
24
Hamilton
2022-10-04
Recruiting
Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection
NCT05219110Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection, Hemolytic-Uremic Syndrome
University of Calgary
Not applicable
1,040
Calgary, Edmonton, Hamilton, Toronto
2022-09-29
Active, closed
PharmaEssentia
Phase 2
91
Calgary, Vancouver, Hamilton, Toronto
2022-09-29
Recruiting
Soluble Fibre Supplementation in NAFLD
NCT05480696Non-Alcoholic Fatty Liver Disease, Non Alcoholic Steatohepatitis, Hepatic Steatosis
McMaster University
Phase 2
60
Hamilton
2022-09-09
By invitation
Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease
NCT04905693Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease, Progressive Pulmonary Fibrosis
DrugTreprostinil
United Therapeutics
Phase 3
1,850
Vancouver, Ajax, Hamilton, Toronto, Trois-Rivières, Québec
2022-09-06
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Canadian investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 12 November 2026. https://priyalifescience.com/clinical-trials-canada/city/hamilton

Query this register directly
GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Canada and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 6,553 studies in total at the last sync on 10 Nov 2026, 03:20 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 811 of those studies with a site in Hamilton.

How many clinical trials are recruiting in Hamilton?

431 of the 811 studies on this page are recruiting new participants as of the 10 Nov 2026, 03:20 UTC sync. A further 46 have not yet opened recruitment, 318 are active but closed to new participants, and 16 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Hamilton), 811 studies
PhaseStudiesRecruitingShare
Phase 332415040%
Not applicable18810123.2%
Phase 21095113.4%
Observational1047212.8%
Phase 428193.5%
Phase 124193%
Phase 1/217102.1%
Phase 2/31571.8%
Early Phase 1220.2%

Most active sponsors

Lead sponsors with the most studies (Hamilton)
Lead sponsorStudiesRecruiting
McMaster University10959
AstraZeneca4627
Canadian Cancer Trials Group3218
National Cancer Institute (NCI)267
Population Health Research Institute2418
St. Joseph's Healthcare Hamilton2414
Hamilton Health Sciences Corporation2316
Children's Oncology Group2210
Eli Lilly and Company2012
Merck Sharp & Dohme LLC197
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.