Multiprofen-CC to Reduce Pain in Hand Arthritis

Condition(s) studied

Investigational drug(s) / intervention(s)

Multiprofen-CC™ plus standard treatment: Standard care pain medications and topical Multiprofen-CC™ (1g TID) for 2 weeks

Placebo plus standard treatment: Standard care pain medications and visually identical topical placebo (1g TID) for 2 weeks

Study summary

This clinical trial aims to find out if using 1 gram of Multiprofen-CC cream on the hands three times a day for 4 weeks can help reduce pain in adults with hand osteoarthritis, compared to a placebo (a cream with no active medicine). The research team will also look at how Multiprofen-CC affects hand function, opioid use, and how patients feel about their overall improvement. In addition, the research team will keep track of any side effects.

Participants will:

* Use both Multiprofen-CC and a placebo (a cream with no active medicine) during the study, in a random order.
* Be asked to apply 1 gram of cream to their hands three times a day for 2 weeks, following the manufacturer's instructions.
* Attend a visit before starting the study, after 2 weeks, and after 6 weeks.
* Report any symptoms they experience during the study.

Eligibility

Primary outcome measure(s)

• Pain intensity — baseline [week 0] and weeks 2, 4, and 6
  Average pain intensity will be measured using a 0-10 Numeric Rating Scale (NRS), where 0 represents "no pain" and 10 represents "worst imaginable pain." Scores are collected before and after each treatment period. Higher scores indicate greater pain intensity and thus a worse outcome.

Trial sites (1)

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