Aln-App clinical trials
Aln-App is named as an intervention in 3 current clinical trials in our USA, UK, Netherlands, Canada, Switzerland, Australia and Spain registers. 2 are recruiting patients now. The most common phase is Phase 2. The lead sponsor is Alnylam Pharmaceuticals. The most-studied condition is Early-Onset Alzheimer Disease.
Patient leaflets for Aln-App
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Trials by status
Trials by phase
Clinical trials of Aln-App
3 trials| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)
NCT07636811 · Down Syndrome-Associated Alzheimer's Disease (DS-AD)
|
Phase 2 | Recruiting | Alnylam Pharmaceuticals | USA, Spain |
|
A Study to Evaluate the Safety and Tolerability of ALN-APP in Patients With EOAD
NCT05231785 · Early-Onset Alzheimer Disease
|
Phase 1 | Recruiting | Alnylam Pharmaceuticals | UK, USA, Netherlands, Canada |
|
A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy
NCT06393712 · Cerebral Amyloid Angiopathy
|
Phase 2 | Active, closed | Alnylam Pharmaceuticals | UK, USA, Netherlands, Switzerland, Canada, Australia |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Conditions studied with Aln-App
3 conditionsSponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| Alnylam Pharmaceuticals | 3 |
By country register
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in USA | 3 | 2 |
| Clinical trials in UK | 2 | 1 |
| Clinical trials in Netherlands | 2 | 1 |
| Clinical trials in Canada | 2 | 1 |
| Clinical trials in Switzerland | 1 | 0 |
| Clinical trials in Australia | 1 | 0 |
| Clinical trials in Spain | 1 | 1 |
A trial with sites in more than one country appears in each of those registers.
Related compounds
Questions about Aln-App trials
How many clinical trials are testing Aln-App?
3 current trials in our USA, UK, Netherlands, Canada, Switzerland, Australia and Spain registers name Aln-App as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.
Are Aln-App trials recruiting patients?
Yes. 2 of the 3 trials are recruiting: 2 with sites in USA, 1 with sites in UK, 1 with sites in Netherlands, 1 with sites in Canada and 1 with sites in Spain. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Aln-App clinical trials?
The lead sponsor is Alnylam Pharmaceuticals. The number in brackets is how many trials each organisation leads.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Aln-App works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Aln-App works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Aln-App (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.