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Compound · clinical trials

Xofigo clinical trials

Also listed in trial records as Radium-223, Radium Chloride Ra-223
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 5 trials in our Spain, Sweden, Brazil, Australia, UK, USA, India, China, Germany, France, Poland, Austria, Turkey, Canada, Japan, South Korea, Taiwan, Israel, Netherlands, Mexico, Italy, Belgium, Switzerland and Norway registers that name Xofigo as an intervention. Synced 26 Sep 2026
5Current trials
2Recruiting now
5Lead sponsors
24Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Xofigo is named as an intervention in 5 current clinical trials in our Spain, Sweden, Brazil, Australia, UK, USA, India, China, Germany, France, Poland, Austria, Turkey, Canada, Japan, South Korea, Taiwan, Israel, Netherlands, Mexico, Italy, Belgium, Switzerland and Norway registers. 2 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is AstraZeneca (1). The most-studied condition is Metastatic Castration-resistant Prostate Cancer. The EU clinical trials register (CTIS) separately lists 1 authorised or ongoing trial.

Trials by status

  • Recruiting240%
  • Active, closed360%

Trials by phase

  • Phase 3360%
  • Phase 2120%
  • Phase 1/2120%
01

Clinical trials of Xofigo

5 trials
StudyPhaseStatusLead sponsorRegisters
ProBio: A Biomarker Driven Study in Patients With Metastatic Prostate Cancer
NCT03903835 · ClinicalTrials.gov ↗ · Metastatic Castration-resistant Prostate Cancer (mCRPC), Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)
Phase 3 Recruiting Karolinska Institutet Belgium, Sweden, Switzerland, Norway
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
NCT07611110 · Metastatic Castration-resistant Prostate Cancer
Phase 3 Recruiting AstraZeneca UK, USA, India, China, Germany, France, Spain, Sweden, Poland, Austria, Turkey, Canada, Brazil, Japan, South Korea, Taiwan, Australia, Israel
A Study to Test Radium-223 With Docetaxel in Patients With Prostate Cancer
NCT03574571 · ClinicalTrials.gov ↗ · Prostate Cancer
Phase 3 Active, closed Memorial Sloan Kettering Cancer Center Spain, Netherlands, Brazil, Mexico
Sequencing of Radium-223 and Docetaxel in Symptomatic Bone-only Metastatic Castration-resistant Prostate Cancer
NCT03230734 · ClinicalTrials.gov ↗ · Metastatic Castration-resistant Prostate Cancer
Phase 2 Active, closed Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS Italy
Combination of Radium-223 and Lutetium-177 PSMA-I&T in Men with Metastatic Castration-Resistant Prostate Cancer
NCT05383079 · ClinicalTrials.gov ↗ · Metastatic Castration-resistant Prostate Cancer, MCRPC, Prostate Cancer
Phase 1/2 Active, closed Peter MacCallum Cancer Centre, Australia Australia

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Xofigo in the EU trials register (CTIS)

1 trial

Authorised or ongoing trials in the EU Clinical Trials Information System that list a product containing Xofigo. Many trials are registered in both CTIS and ClinicalTrials.gov, so these are shown separately rather than added to the count above. Trials with a site in Ireland are listed first.

StudyPhaseStatusSponsorCountries
Quantitative Unified Assessment of Novel Triplet therapy and Unconventional Maintenance with Radium-223 for High-Volume Metastatic Hormone Sensitive Prostate Cancer: A Phase II Pilot Trial
2026-525550-11-00 · Male Urogenital Diseases
Phase 2 Authorised Alianza Multidisciplinar Para La Investigacion De Los Tumores Genitourinarios Guard Spain
03

Conditions studied with Xofigo

5 conditions
04

Sponsors

lead sponsor per trial
Lead sponsorTrials
AstraZeneca1
Memorial Sloan Kettering Cancer Center1
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS1
Peter MacCallum Cancer Centre, Australia1
Karolinska Institutet1
05

By country register

RegisterTrialsRecruiting
Clinical trials in Spain21
Clinical trials in Sweden22
Clinical trials in Brazil21
Clinical trials in Australia21
Clinical trials in UK11
Clinical trials in USA11
Clinical trials in India11
Clinical trials in China11
Clinical trials in Germany11
Clinical trials in France11
Clinical trials in Poland11
Clinical trials in Austria11
Clinical trials in Turkey11
Clinical trials in Canada11
Clinical trials in Japan11
Clinical trials in South Korea11
Clinical trials in Taiwan11
Clinical trials in Israel11
Clinical trials in Netherlands10
Clinical trials in Mexico10
Clinical trials in Italy10
Clinical trials in Belgium11
Clinical trials in Switzerland11
Clinical trials in Norway11
EU register (CTIS)1—

A trial with sites in more than one country appears in each of those registers. CTIS does not publish a recruiting flag; its trials may also appear in the registers above.

06

Related compounds

07

Questions about Xofigo trials

How many clinical trials are testing Xofigo?

5 current trials in our Spain, Sweden, Brazil, Australia, UK, USA, India, China, Germany, France, Poland, Austria, Turkey, Canada, Japan, South Korea, Taiwan, Israel, Netherlands, Mexico, Italy, Belgium, Switzerland and Norway registers name Xofigo (also registered as Radium-223) as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Xofigo trials recruiting patients?

Yes. 2 of the 5 trials are recruiting: 1 with sites in Spain, 2 with sites in Sweden, 1 with sites in Brazil, 1 with sites in Australia, 1 with sites in UK, 1 with sites in USA, 1 with sites in India, 1 with sites in China, 1 with sites in Germany, 1 with sites in France, 1 with sites in Poland, 1 with sites in Austria, 1 with sites in Turkey, 1 with sites in Canada, 1 with sites in Japan, 1 with sites in South Korea, 1 with sites in Taiwan, 1 with sites in Israel, 1 with sites in Belgium, 1 with sites in Switzerland and 1 with sites in Norway. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Xofigo clinical trials?

AstraZeneca (1), Memorial Sloan Kettering Cancer Center (1), Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS (1) and Peter MacCallum Cancer Centre, Australia (1), among 5 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Xofigo works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Xofigo works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Xofigo (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.