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Compound · clinical trials

Hydrocortisone Sodium Succinate clinical trials

Also listed in trial records as 20-dione, A-Hydrocort, Corlan
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 7 trials in our Canada, Israel, Mexico, Australia, Brazil, Japan and Singapore registers that name Hydrocortisone Sodium Succinate as an intervention. Synced 26 Sep 2026
7Current trials
4Recruiting now
5Lead sponsors
7Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Hydrocortisone Sodium Succinate is named as an intervention in 7 current clinical trials in our Canada, Israel, Mexico, Australia, Brazil, Japan and Singapore registers. 4 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is National Cancer Institute (NCI) (3). The most-studied condition is Recurrent Acute Leukemia of Ambiguous Lineage.

Trials by status

  • Recruiting457%
  • Active, closed343%

Trials by phase

  • Phase 2343%
  • Phase 3229%
  • Phase 1/2229%
01

Clinical trials of Hydrocortisone Sodium Succinate

7 trials
StudyPhaseStatusLead sponsorRegisters
Stress Hydrocortisone In Pediatric Septic Shock
NCT03401398 · ClinicalTrials.gov ↗ · Septic Shock
Phase 3 Recruiting Jerry Zimmerman Canada, Brazil, Japan, Singapore, Israel
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
NCT04546399 · ClinicalTrials.gov ↗ · Down Syndrome, Recurrent B Acute Lymphoblastic Leukemia
Phase 2 Recruiting National Cancer Institute (NCI) Canada, Australia, Israel
Progestins for the Treatment of Endometrial Cancer or Precancers of the Uterus Before Surgery, The Pro-Window Trial
NCT07436793 · ClinicalTrials.gov ↗ · Endometrial Endometrioid Adenocarcinoma, Endometrial Hyperplasia
Phase 2 Recruiting New Mexico Cancer Research Alliance Mexico
Elotuzumab + Iberdomide + Dexamethasone Post Ide-Cel in RRMM
NCT06518551 · ClinicalTrials.gov ↗ · Myeloma, Multiple Myeloma, Refractory Multiple Myeloma
Phase 1/2 Recruiting Omar Nadeem, MD Israel
Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma
NCT04759586 · ClinicalTrials.gov ↗ · Primary Mediastinal Large B-Cell Lymphoma
Phase 3 Active, closed National Cancer Institute (NCI) Canada, Australia
A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia
NCT05761171 · ClinicalTrials.gov ↗ · Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage
Phase 2 Active, closed Children's Oncology Group Canada, Mexico, Israel
Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers
NCT05538897 · ClinicalTrials.gov ↗ · FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma, Metastatic Endometrial Endometrioid Adenocarcinoma
Phase 1/2 Active, closed National Cancer Institute (NCI) Mexico

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Hydrocortisone Sodium Succinate

17 conditions
Recurrent Acute Leukemia of Ambiguous Lineage1Recurrent Acute Lymphoblastic Leukemia1Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage1Recurrent Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged1Down Syndrome1Recurrent B Acute Lymphoblastic Leukemia1Septic Shock1Primary Mediastinal Large B-Cell Lymphoma1Endometrial Endometrioid Adenocarcinoma1Endometrial Hyperplasia1FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma1FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma1
All 17 conditions
Condition (as registered)Trials
Recurrent Acute Leukemia of Ambiguous Lineage1
Recurrent Acute Lymphoblastic Leukemia1
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage1
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged1
Down Syndrome1
Recurrent B Acute Lymphoblastic Leukemia1
Septic Shock1
Primary Mediastinal Large B-Cell Lymphoma1
Endometrial Endometrioid Adenocarcinoma1
Endometrial Hyperplasia1
FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma1
FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma1
Metastatic Endometrial Endometrioid Adenocarcinoma1
Recurrent Endometrial Endometrioid Adenocarcinoma1
Myeloma1
Multiple Myeloma1
Refractory Multiple Myeloma1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
National Cancer Institute (NCI)3
Children's Oncology Group1
Jerry Zimmerman1
New Mexico Cancer Research Alliance1
Omar Nadeem, MD1
04

By country register

RegisterTrialsRecruiting
Clinical trials in Canada42
Clinical trials in Israel43
Clinical trials in Mexico31
Clinical trials in Australia21
Clinical trials in Brazil11
Clinical trials in Japan11
Clinical trials in Singapore11

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Hydrocortisone Sodium Succinate trials

How many clinical trials are testing Hydrocortisone Sodium Succinate?

7 current trials in our Canada, Israel, Mexico, Australia, Brazil, Japan and Singapore registers name Hydrocortisone Sodium Succinate (also registered as 20-dione) as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Hydrocortisone Sodium Succinate trials recruiting patients?

Yes. 4 of the 7 trials are recruiting: 2 with sites in Canada, 3 with sites in Israel, 1 with sites in Mexico, 1 with sites in Australia, 1 with sites in Brazil, 1 with sites in Japan and 1 with sites in Singapore. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Hydrocortisone Sodium Succinate clinical trials?

National Cancer Institute (NCI) (3), Children's Oncology Group (1), Jerry Zimmerman (1) and New Mexico Cancer Research Alliance (1), among 5 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Hydrocortisone Sodium Succinate works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Hydrocortisone Sodium Succinate works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Hydrocortisone Sodium Succinate (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.