Maintained by Sreepriya Prasannan

MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist

Compiled from ClinicalTrials.gov registry records · Last verified 26 Sep 2026 · Editorial standards

At a glance

Dexmedetomidine is named as an intervention in 56 current clinical trials in our China, USA, UK and India registers. 35 are recruiting patients now. The most common phase is Not applicable. The sponsor with the most trials is Pfizer (4). The most-studied condition is Dexmedetomidine.

Trials by status

Recruiting3563%
Not yet open1018%
Active, closed814%
By invitation35%

Trials by phase

Not applicable1730%
Phase 11425%
Phase 41221%
Phase 359%
Phase 1/235%
Phase 235%
Phase EARLY_PHASE112%
Observational12%

Clinical trials of Dexmedetomidine

56 trials

Study	Phase	Status	Lead sponsor	Registers
Comparison of Perioperative Conscious Sedation During Endovascular Thrombectomy in Acute Ischemic Stroke NCT06139692 · ClinicalTrials.gov ↗ · Acute Ischemic Stroke	Phase 4	Recruiting	Jinling Hospital, China	China
Dexmedetomidine Reduces Sevoflurane MAC-BAR During Pneumoperitoneum NCT06575179 · ClinicalTrials.gov ↗ · Laparoscopic Cholecystectomy	Phase 4	Recruiting	Fujian Provincial Hospital	China
Determination of ED50 and ED95 With Clinical Efficacy of Intranasal Dexmedetomidine Combined With Esketamine for Preoperative Sedation in Pediatric General Anesthesia NCT06853431 · ClinicalTrials.gov ↗ · Preoperative Anxiety, Preoperative Sedation, Children	Phase 4	Recruiting	Second Affiliated Hospital of Wenzhou Medical University	China
The Electroencephalographic Mechanisms of Anesthesia and Human Consciousness NCT07145697 · ClinicalTrials.gov ↗ · Consciousness, Level Altered	Phase 4	Recruiting	Guangzhou General Hospital of Guangzhou Military Command	China
Impact of Perioperative Dexmedetomidine and Esketamine on Postoperative Quality of Recovery NCT07308756 · ClinicalTrials.gov ↗ · General Anesthesia, Surgery, Dexmedetomidine	Phase 4	Recruiting	Peking University First Hospital	China
Effect of Dexmedetomidine Combined With FNB/ACB on Sleep Quality After Knee Surgery NCT07767383 · ClinicalTrials.gov ↗ · Knee Arthroscopic Surgery	Phase 4	Recruiting	Affiliated Hospital of Nantong University	China
(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors NCT05208047 · ClinicalTrials.gov ↗ · Advanced Gastrointestinal Stromal Tumors, Metastatic Cancer	Phase 3	Recruiting	Cogent Biosciences, Inc.	UK, USA, China
A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy NCT05646862 · Breast Cancer	Phase 3	Recruiting	Hoffmann-La Roche	UK, USA, China
Safety and Efficacy of Dexmedetomidate vs. Midazolam for Procedural Sedation During Medical Thoracoscopy NCT07184801 · ClinicalTrials.gov ↗ · Medical Thoracoscopy	Phase 3	Recruiting	Post Graduate Institute of Medical Education and Research, Chandigarh	India
A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder NCT07227454 · ClinicalTrials.gov ↗ · Depressive Disorder, Major	Phase 3	Recruiting	Janssen Research & Development, LLC	USA
Intranasal Dexmedetomidine for Acute Anxiety State in Adults NCT07550881 · ClinicalTrials.gov ↗ · Acute Anxiety States	Phase 2	Recruiting	Tongji University	China
A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1) NCT05384626 · ClinicalTrials.gov ↗ · Locally Advanced Solid Tumor, Metastatic Solid Tumor	Phase 1/2	Recruiting	Nuvalent Inc.	UK, USA
FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3 NCT05614739 · Urinary Bladder Neoplasms, Neoplasm Metastasis, Ureteral Neoplasms	Phase 1	Recruiting	Eli Lilly and Company	UK, USA, China
Effect of Different Administration Routes of Dexmedetomidine Combined with Ultrasound-Guided Fascia Iliaca Block on Emergence Agitation After Hip Replacement Surgery NCT06614010 · ClinicalTrials.gov ↗ · Dexmedetomidine, Fascia Iliaca Block	Phase 1	Recruiting	Qianfoshan Hospital	China
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations NCT06835569 · ClinicalTrials.gov ↗ · Cancer, PDAC - Pancreatic Ductal Adenocarcinoma, NSCLC (Non-small Cell Lung Cancer)	Phase 1	Recruiting	Alterome Therapeutics, Inc.	USA
An Open-Label Drug Interaction Clinical Study to Evaluate Itraconazole, Rifampin, Midazolam and SIM0270 in Chinese Healthy Adult Participants NCT07357610 · ClinicalTrials.gov ↗ · Healthy Adult Participants	Phase 1	Recruiting	Jiangsu Simcere Pharmaceutical Co., Ltd.	China
An Open-Label Study to Evaluate PF-07994525 in Participants With Advanced Cancers NCT07426757 · ClinicalTrials.gov ↗ · Advanced Malignancies, Advanced Cancer	Phase 1	Recruiting	Pfizer	USA
A Study to Investigate the Safety and PK of VH4770359 in Healthy Participants NCT07525544 · ClinicalTrials.gov ↗ · HIV Infections	Phase 1	Recruiting	ViiV Healthcare	USA
A Phase 1, First-in-human Study of VX-433 NCT07584434 · ClinicalTrials.gov ↗ · Narcolepsy Type 1 (NT1)	Phase 1	Recruiting	Vertex Pharmaceuticals Incorporated	USA
A Study to Assess the Effect of HRS-1301 on the Pharmacokinetics of Midazolam and Atorvastatin in Healthy Participants NCT07608705 · ClinicalTrials.gov ↗ · Hyperlipidemias	Phase 1	Recruiting	Shandong Suncadia Medicine Co., Ltd.	China
A Study to Learn How Different Amounts of the Study Medicine Called PF-08103402 Are Tolerated and Act in the Body in Healthy Adults or Adults With Mild To-moderate Asthma NCT07660731 · ClinicalTrials.gov ↗ · Healthy Volunteer Study, Healthy Adults, Healthy Participants	Phase 1	Recruiting	Pfizer	USA
An Early-Stage Study in Multiple Clinics of How Afimkibart May Affect the Body's Processing of Medicines That Rely on Cytochrome P450 Enzymes in Participants With Ulcerative Colitis NCT07665723 · ClinicalTrials.gov ↗ · Active Ulcerative Colitis	Phase 1	Recruiting	Hoffmann-La Roche	UK, USA
Drug-Interaction Assessment of GSK3772701 in Healthy Male and Female Participants Aged 18 to 55 Years NCT07670377 · ClinicalTrials.gov ↗ · Malaria, Falciparum	Phase 1	Recruiting	GlaxoSmithKline	USA
A Study of LY4355756 in Healthy Participants NCT07765498 · ClinicalTrials.gov ↗ · Healthy	Phase 1	Recruiting	Eli Lilly and Company	USA
The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma NCT06138340 · ClinicalTrials.gov ↗ · Brain Network Connectivity, Postoperative Delirium, Dexmedetomidine	Observational	Recruiting	Beijing Tiantan Hospital	China
Cardioprotective Effect of Dexmedetomidine in Patients With ST-segment Elevation Myocardial Infarction NCT04912518 · ClinicalTrials.gov ↗ · ST-segment Elevation Myocardial Infarction (STEMI), Percutaneous Coronary Intervention, Cardioprotection	Not applicable	Recruiting	Harbin Medical University	China
Effect of Remimazolam With Protocolized Sedation on Critical Ill, Mechanical Ventilated Patients Compared With Midazolam NCT05160987 · ClinicalTrials.gov ↗ · Sedation and Analgesia	Not applicable	Recruiting	Zhujiang Hospital	China
Effect of Dexmedetomidine on Postoperative Delirium After Awake Craniotomies NCT05195034 · ClinicalTrials.gov ↗ · Dexmedetomidine, Delirium, Awake Craniotomy	Not applicable	Recruiting	Beijing Tiantan Hospital	China
Remimazolam for Postoperative Atrial Fibrillation NCT05891145 · ClinicalTrials.gov ↗ · Coronary Artery Bypass Grafting, Remimazolam	Not applicable	Recruiting	Yangzhou University	China
Perioperative Dexmedetomidine and Long-term Survival After Cancer Surgery NCT06030804 · ClinicalTrials.gov ↗ · Elderly, Cancer Surgery, Dexmedetomidine	Not applicable	Recruiting	Peking University First Hospital	China
Perioperative Dexmedetomidine on Postoperative Delirium in Patients With Brain Tumors NCT06164314 · ClinicalTrials.gov ↗ · Postoperative Delirium	Not applicable	Recruiting	Beijing Tiantan Hospital	China
Preoperative Oral Midazolam to Postoperative Pain Relief in Sleep Disturbance or Anxiety Patients With Colorectal Cancer NCT06407518 · ClinicalTrials.gov ↗ · Preoperative, Sleep Disturbance, Anxiety	Not applicable	Recruiting	Sixth Affiliated Hospital, Sun Yat-sen University	China
Effects of Esketamine Combined With Dexmedetomidine on Postoperative Sleep Quality NCT07002723 · ClinicalTrials.gov ↗ · Hip Fractures	Not applicable	Recruiting	Peking University Shenzhen Hospital	China
Effects of taVNS Combined With Dexmedetomidine on POVN NCT07271147 · ClinicalTrials.gov ↗ · Postoperative Nausea and Vomiting	Not applicable	Recruiting	Affiliated Hospital of Nantong University	China
Dexmedetomidine Combined With Transcutaneous Vagus Nerve Stimulation (taVNS) Can Reduce the Incidence of PTSD in Trauma Patients After Surgery NCT07813962 · ClinicalTrials.gov ↗ · PTSD - Post Traumatic Stress Disorder, taVNS, Dexmedetomidine	Not applicable	Recruiting	Affiliated Hospital of Nantong University	China
Effect of Opioid-free Anaesthesia on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Surgery NCT06958393 · ClinicalTrials.gov ↗ · Delirium - Postoperative, Opioid-Free Anaesthesia	Phase 4	Not yet open	Qianfoshan Hospital	China
Safety and Efficacy of Esketamine - Dexmedetomidine Combination Versus Dexmedetomidine Monotherapy for Hyperactive Delirium in ICU Patients on Non-Invasive Respiratory Support (SEED-NIRS Trial): Study Protocol of a Randomized Controlled Trial NCT07377981 · ClinicalTrials.gov ↗ · Dexmedetomidine, Ketamine, Analgesia	Phase 4	Not yet open	The First Affiliated Hospital with Nanjing Medical University	China
Intranasal Dexmedetomidine or Esketamine for Negative Postoperative Behavioral Changes in Children NCT07570160 · ClinicalTrials.gov ↗ · Behavior Problem	Phase 4	Not yet open	Nanjing Children's Hospital	China
A Study Comparing Oral Ketamine With Oral Midazolam for the Treatment of Major Depressive Episodes NCT07839338 · Major Depressive Episode	Phase 3	Not yet open	Jawaharlal Institute of Postgraduate Medical Education & Research	India
Dexmedetomidine-Esketamine Combination for Sedation and Analgesia in ICU Patients NCT06468436 · ClinicalTrials.gov ↗ · Aged, Intensive Care Units, Ventilators, Mechanical	Not applicable	Not yet open	Peking University First Hospital	China
Intranasal Dexmedetomidine for Prevention of Intrapartum Fever NCT07501221 · ClinicalTrials.gov ↗ · Intrapartum Fever	Not applicable	Not yet open	Chengdu Jinjiang Maternity and Child Health Hospital	China
Intranasal Dexmedetomidine for Postpartum Depression Prevention NCT07501728 · ClinicalTrials.gov ↗ · Postpartum Depression (PPD)	Not applicable	Not yet open	Chengdu Jinjiang Maternity and Child Health Hospital	China
Effects of Dexmedetomidine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic Shock NCT07657715 · ClinicalTrials.gov ↗ · Septic Shock, Sepsis, Critical Illness	Not applicable	Not yet open	First Affiliated Hospital of Wannan Medical College	China
The Effects of Midazolam, Dexmedetomidine, and Esketamine on Bispectral Index and Raw Electroencephalogram in Patients Under Propofol-Remifentanil Baseline Anesthesia NCT07699523 · ClinicalTrials.gov ↗ · Depth of Anesthesia Monitoring, BIS-EEG	Not applicable	Not yet open	China-Japan Friendship Hospital	China
The Impact of Dexmedetomidine Nasal Spray on Perioperative Anxiety in Neurosurgical Patients NCT07801014 · ClinicalTrials.gov ↗ · Anxiety, Dexmedetomidine	Not applicable	Not yet open	Beijing Tiantan Hospital	China
a Prospective Randomised Study Evaluating the Efficacy of Intranasal Midazolam and Dexmedetomidine as a Sedative Agent in Management of Mandible Fracture NCT07502651 · ClinicalTrials.gov ↗ · Sedation	Phase EARLY_PHASE1	By invitation	Postgraduate Institute of Dental Sciences Rohtak	India
Effect of Remazolam Besylate Combined With Remifentanil Analgesic Sedation on the Prognosis of Patients With Sepsis NCT06731088 · ClinicalTrials.gov ↗ · Sepsis	Phase 4	By invitation	First Affiliated Hospital of Ningbo University	China
Effect of Perioperative Dexmedetomidine on Chronic Post-Surgical Pain NCT06849466 · ClinicalTrials.gov ↗ · Chronic Post-Surgical Pain	Phase 4	By invitation	Peking Union Medical College Hospital	China
The Improvement of Low-dose Esketamine on Postoperative Depression in Patients Undergoing Bariatric Surgery With Preoperative Depression NCT07179913 · ClinicalTrials.gov ↗ · Depressed, Bariatric Surgery	Phase 4	Active, closed	The First Hospital of Jilin University	China
An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer NCT02365597 · ClinicalTrials.gov ↗ · Urothelial Cancer	Phase 2	Active, closed	Janssen Research & Development, LLC	UK, USA, India
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors NCT04557449 · ClinicalTrials.gov ↗ · Liposarcoma, Prostate Cancer, Breast Neoplasms	Phase 2	Active, closed	Pfizer	UK, USA, China
Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer NCT03436485 · ClinicalTrials.gov ↗ · Prostate Cancer Metastatic	Phase 1/2	Active, closed	Orion Corporation, Orion Pharma	UK, USA
First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia NCT04067336 · ClinicalTrials.gov ↗ · Advanced Malignant Neoplasm, Acute Myeloid Leukemia, Mixed Lineage Leukemia	Phase 1/2	Active, closed	Kura Oncology, Inc.	USA
A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation NCT04973163 · ClinicalTrials.gov ↗ · Solid Tumors, KRAS Mutation	Phase 1	Active, closed	Boehringer Ingelheim	UK, USA
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations. NCT05355701 · ClinicalTrials.gov ↗ · Melanoma, Non-Small-Cell Lung Cancer, Thyroid Cancer	Phase 1	Active, closed	Pfizer	USA
Dexmedetomidine and Outcomes of Elderly Admitted to ICU After Surgery NCT04204798 · ClinicalTrials.gov ↗ · Elderly, Surgery, Intensive Care Unit	Not applicable	Active, closed	Peking University First Hospital	China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

Dexmedetomidine across our data

Ireland · EU · US

The same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.

Licensed in Ireland (HPRA)

7 single-substance products containing Dexmedetomidine on the HPRA medicines list.

Dexmedetomidine 100 micrograms/ml concentrate for solution for infusionAS Kalceks · PA2165/010/001 · Marketed
Dexmedetomidine B. Braun 100 micrograms/ml concentrate for solution for infusionB. Braun Melsungen AG · PA0736/042/001 · Marketed
Dexmedetomidine EVER Pharma 100 micrograms/ml concentrate for solution for infusionEVER Valinject GmbH · PA1774/002/001 · Marketed
Dexdor 100 micrograms/ml concentrate for solution for infusionOrion Corporation · EU/1/11/718/001-006
Dexmedetomidine 100 microgram/ml concentrate for solution for infusionNoridem Enterprises Limited · PA1122/048/001 · Not marketed

All 7 Irish products →

Supply shortages

Dexmedetomidine Hydrochloride InjectionUS (FDA) · Current · updated 21 Sep 2026

EU shortages US shortages German shortages

Conditions studied with Dexmedetomidine

99 conditions

Dexmedetomidine11 Anxiety2 Sepsis2 Surgery2 Elderly2 Postoperative Delirium2 Urinary Bladder Neoplasms1 Neoplasm Metastasis1Ureteral Neoplasms1Breast Cancer1Advanced Gastrointestinal Stromal Tumors1Metastatic Cancer1

All 99 conditions

Condition (as registered)	Trials
Dexmedetomidine	11
Anxiety	2
Sepsis	2
Surgery	2
Elderly	2
Postoperative Delirium	2
Urinary Bladder Neoplasms	1
Neoplasm Metastasis	1
Ureteral Neoplasms	1
Breast Cancer	1
Advanced Gastrointestinal Stromal Tumors	1
Metastatic Cancer	1
Locally Advanced Solid Tumor	1
Metastatic Solid Tumor	1
Urothelial Cancer	1
Solid Tumors, KRAS Mutation	1
Prostate Cancer Metastatic	1
Liposarcoma	1
Prostate Cancer	1
Breast Neoplasms	1
Adenocarcinoma of Lung	1
Active Ulcerative Colitis	1
Narcolepsy Type 1 (NT1)	1
Healthy	1
Malaria, Falciparum	1
Depressive Disorder, Major	1
Healthy Volunteer Study	1
Healthy Adults	1
Healthy Participants	1
Asthma	1
Melanoma	1
Non-Small-Cell Lung Cancer	1
Thyroid Cancer	1
Glioma	1
Advanced Malignancies	1
Advanced Cancer	1
HIV Infections	1
Advanced Malignant Neoplasm	1
Acute Myeloid Leukemia	1
Mixed Lineage Leukemia	1
Mixed Lineage Acute Leukemia	1
Cancer	1
PDAC - Pancreatic Ductal Adenocarcinoma	1
NSCLC (Non-small Cell Lung Cancer)	1
CRC (Colorectal Cancer)	1
Major Depressive Episode	1
Medical Thoracoscopy	1
Sedation	1
Coronary Artery Bypass Grafting	1
Remimazolam	1
Sedation and Analgesia	1
Hyperlipidemias	1
Depth of Anesthesia Monitoring	1
BIS-EEG	1
Preoperative	1
Sleep Disturbance	1
Midazolam	1
Acute Ischemic Stroke	1
Healthy Adult Participants	1
General Anesthesia	1
Esketamine	1
Depressed	1
Bariatric Surgery	1
Knee Arthroscopic Surgery	1
Intrapartum Fever	1
ST-segment Elevation Myocardial Infarction (STEMI)	1
Percutaneous Coronary Intervention	1
Cardioprotection	1
PTSD - Post Traumatic Stress Disorder	1
taVNS	1
Fascia Iliaca Block	1
Postpartum Depression (PPD)	1
Delirium	1
Awake Craniotomy	1
Intensive Care Unit	1
Laparoscopic Cholecystectomy	1
Delirium - Postoperative	1
Opioid-Free Anaesthesia	1
Preoperative Anxiety	1
Preoperative Sedation	1
Children	1
Brain Network Connectivity	1
Propofol	1
Septic Shock	1
Critical Illness	1
Hip Fractures	1
Behavior Problem	1
Chronic Post-Surgical Pain	1
Postoperative Nausea and Vomiting	1
Consciousness, Level Altered	1
Acute Anxiety States	1
Aged	1
Intensive Care Units	1
Ventilators, Mechanical	1
Ketamine	1
Analgesia	1
Respiratory Therapy	1
Cancer Surgery	1
Long-Term Survivors	1

By country register

Register	Trials	Recruiting
Clinical trials in China	38	24
Clinical trials in USA	19	13
Clinical trials in UK	9	5
Clinical trials in India	4	1

A trial with sites in more than one country appears in each of those registers.

Related compounds

Questions about Dexmedetomidine trials

How many clinical trials are testing Dexmedetomidine?

56 current trials in our China, USA, UK and India registers name Dexmedetomidine as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Dexmedetomidine trials recruiting patients?

Yes. 35 of the 56 trials are recruiting: 24 with sites in China, 13 with sites in USA, 5 with sites in UK and 1 with sites in India. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Dexmedetomidine clinical trials?

Pfizer (4), Peking University First Hospital (4), Beijing Tiantan Hospital (4) and Affiliated Hospital of Nantong University (3), among 40 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Is Dexmedetomidine licensed in Ireland?

Yes. The HPRA medicines list includes 7 single-substance products containing Dexmedetomidine, for example Dexmedetomidine 100 micrograms/ml concentrate for solution for infusion (AS Kalceks). A licence does not mean a product is currently marketed or reimbursed; see each product's record.

Is there a Dexmedetomidine shortage?

The registers we track list 1 entry for Dexmedetomidine: US FDA: current. Shortages are product- and country-specific; check with a pharmacist.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Dexmedetomidine works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Dexmedetomidine works or whether it is effective. Each trial links to its own record so you can check it yourself.

ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Dexmedetomidine (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.

Dexmedetomidine clinical trials