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Compound · clinical trials

Propofol clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 25 trials in our China, India and USA registers that name Propofol as an intervention. Synced 25 Sep 2026
25Current trials
11Recruiting now
19Lead sponsors
3Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Propofol is named as an intervention in 25 current clinical trials in our China, India and USA registers. 11 are recruiting patients now. The most common phase is Not applicable. The sponsor with the most trials is Sir Ganga Ram Hospital (2). The most-studied condition is Anesthesia.

Trials by status

  • Recruiting1144%
  • Not yet open1040%
  • Active, closed312%
  • By invitation14%

Trials by phase

  • Not applicable1144%
  • Phase 4832%
  • Phase 328%
  • Observational28%
  • Phase 1/214%
  • Phase 114%
01

Clinical trials of Propofol

25 trials
StudyPhaseStatusLead sponsorRegisters
Impact of Remimazolam on Prognosis After Bladder Cancer Surgery
NCT04532606 · ClinicalTrials.gov ↗ · Benzodiazepines, Bladder Cancer, Delirium
Phase 4 Recruiting Peking University First Hospital China
Evaluation of Propofol Dosing Based on Total Body Weight Using Closes-loop Anaesthesia Delivery System
NCT05305313 · ClinicalTrials.gov ↗ · Obesity, Morbid, Anesthesia, Propofol
Phase 4 Recruiting Sir Ganga Ram Hospital India
Effects of Ciprofol on Myocardial Injury After Non-cardiac Surgery in Video-Assisted Thoracoscopic Surgery
NCT07028593 · ClinicalTrials.gov ↗ · Myocardial Injury, Thoracic Diseases, Thoracoscopic Surgery
Phase 4 Recruiting Tongji Hospital China
A Randomized Controlled Trial Comparing the Effects of Different Anesthetic Sedatives on PONV in Laparoscopic Cholecystectomy
NCT07758803 · ClinicalTrials.gov ↗ · Cholelithiasis, Postoperative Nausea and Vomiting
Phase 4 Recruiting Xi'an Aerospace General Hospital China
Total Intravenous Anesthesia and Recurrence Free Survival
NCT04513808 · ClinicalTrials.gov ↗ · Esophageal Cancer
Phase 3 Recruiting The Cleveland Clinic China
General Anesthetics-related Changes in Prefrontal EEG During Pediatric Surgical Anesthesia
NCT05210764 · ClinicalTrials.gov ↗ · General Anesthetic, Electroencephalogram
Observational Recruiting Peking University First Hospital China
Effects of Propofol on Brain Function in Patients With Parkinson's Disease
NCT05895019 · ClinicalTrials.gov ↗ · PD - Parkinson's Disease
Observational Recruiting Beijing Tiantan Hospital China
Performance Analysis of Hermetic Closed-loop Anesthesia Delivery System
NCT05967403 · ClinicalTrials.gov ↗ · Anesthesia
Not applicable Recruiting Sir Ganga Ram Hospital India
The Effects of Remimazolam on the Incidence of Severe Hypoxia During Sedated Hysteroscopy for Assisted Reproduction in Overweight or Obese Patients
NCT06187896 · ClinicalTrials.gov ↗ · Hypoxia, Hysteroscopy, Overweight or Obesity
Not applicable Recruiting RenJi Hospital China
Remimazolam Besylate in Sedation of Postcardioperative Patients
NCT06716840 · ClinicalTrials.gov ↗ · Remimazolam, Propofol, Sedation
Not applicable Recruiting First Affiliated Hospital of Zhejiang University China
Effects of Fospropofol Disodium TIVA and IVIH on Surgical Field Quality in Adult ESS
NCT07788157 · ClinicalTrials.gov ↗ · Fospropofol Disodium
Not applicable Recruiting Tongji Hospital China
The Effects of Different Anesthetics on the Brain's Neural Networks
NCT07644663 · ClinicalTrials.gov ↗ · Electroencephalogram (EEG), Anesthesia
Phase 4 Not yet open Fudan University China
Ciprofol vs Propofol for Hemodynamic Stability in Patients Having General Anesthesia for Endovascular Thrombectomy After Ischemic Stroke
NCT07696208 · Hemodynamic Stability, Ischemic Strokes
Phase 4 Not yet open RenJi Hospital China
Remimazolam Versus Propofol for Maintenance of Anaesthesia During Major Hepatectomy Under Low Central Venous Pressure
NCT07789275 · ClinicalTrials.gov ↗ · Intraoperative Hypotension, Hepatectomy
Phase 4 Not yet open Beijing Tsinghua Chang Gung Hospital China
The Impact of Remimazolam Tosilate on Oxygenation and Postoperative Cognitive Function in Elderly Patients Undergoing Thoracoscopic Lobectomy
NCT07086911 · ClinicalTrials.gov ↗ · Remimazolam Besylate, Thoracoscopic Lobectomy, Oxygenation
Phase 1/2 Not yet open Jinqiao Qian China
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of KL0011034 Injection Administered by Continuous Infusion in Healthy Adult Subjects
NCT07828470 · ClinicalTrials.gov ↗ · Healthy Volunteers
Phase 1 Not yet open Hunan Kelun Pharmaceutical Co., Ltd. China
The Effect of General Anesthesia with Remimazolam and Propofol on Rhythmic State and Cognitive Function
NCT06775366 · ClinicalTrials.gov ↗ · Cognitive Functioning, Propofol, Remimazolam
Not applicable Not yet open The Second Affiliated Hospital of Chongqing Medical University China
The Effects of Midazolam, Dexmedetomidine, and Esketamine on Bispectral Index and Raw Electroencephalogram in Patients Under Propofol-Remifentanil Baseline Anesthesia
NCT07699523 · ClinicalTrials.gov ↗ · Depth of Anesthesia Monitoring, BIS-EEG
Not applicable Not yet open China-Japan Friendship Hospital China
Remimazolam Versus Propofol for Early Recovery After Cytoreductive Surgery
NCT07785557 · ClinicalTrials.gov ↗ · Peritoneal Neoplasms, Postoperative Recovery
Not applicable Not yet open Beijing Tsinghua Chang Gung Hospital China
Ciprofol, Propofol and Sevoflurane for Postoperative Delirium in Elderly Brain Tumor Patients
NCT07799623 · ClinicalTrials.gov ↗ · Brain Neoplasms, Delirium - Postoperative
Not applicable Not yet open Union Hospital, Tongji Medical College, Huazhong University of Science and Technology China
The Effect of Ciprofol Versus Propofol Anesthesia on Postoperative Neurological Complications
NCT07805876 · ClinicalTrials.gov ↗ · Intracranial Tumors
Not applicable Not yet open Beijing Tiantan Hospital China
Effects of Remimazolam on Postoperative Myocardial Injury
NCT07725185 · ClinicalTrials.gov ↗ · Myocardial Injury
Not applicable By invitation Affiliated Hospital of Jiaxing University China
Combination of Remimazolam and Propofol During Drug-induced Sleep Endoscopy
NCT06784479 · ClinicalTrials.gov ↗ · Sedative Effect During Drug-induced Sleep Endoscopy, Obstructive Sleep Apnea (OSA)
Phase 4 Active, closed Dan Liu China
A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol
NCT06809218 · ClinicalTrials.gov ↗ · Post-Intensive Care Syndrome, Sedation
Phase 3 Active, closed Sedana Medical USA
Efficacy of Esketamine Combined With Different General Anesthetics on Quality of Postoperative Recovery
NCT06976996 · ClinicalTrials.gov ↗ · Quality of Postoperative Recovery
Not applicable Active, closed Northern Jiangsu People's Hospital China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Propofol

46 conditions
Anesthesia3Propofol3Sedation2Remimazolam2Myocardial Injury2Post-Intensive Care Syndrome1Obesity, Morbid1Hemodynamic Stability1Ischemic Strokes1Benzodiazepines1Bladder Cancer1Delirium1
All 46 conditions
Condition (as registered)Trials
Anesthesia3
Propofol3
Sedation2
Remimazolam2
Myocardial Injury2
Post-Intensive Care Syndrome1
Obesity, Morbid1
Hemodynamic Stability1
Ischemic Strokes1
Benzodiazepines1
Bladder Cancer1
Delirium1
Surgery1
PD - Parkinson's Disease1
Depth of Anesthesia Monitoring1
BIS-EEG1
Intraoperative Hypotension1
Hepatectomy1
Hypoxia1
Hysteroscopy1
Overweight or Obesity1
Sedative Effect During Drug-induced Sleep Endoscopy1
Obstructive Sleep Apnea (OSA)1
Electroencephalogram (EEG)1
Intracranial Tumors1
Quality of Postoperative Recovery1
Brain Neoplasms1
Delirium - Postoperative1
Mechanical Ventilation1
Cholelithiasis1
Postoperative Nausea and Vomiting1
Fospropofol Disodium1
General Anesthetic1
Electroencephalogram1
Cognitive Functioning1
Circadian Rhythm1
Remimazolam Besylate1
Thoracoscopic Lobectomy1
Oxygenation1
Postoperative Cognitive Dysfunction1
Peritoneal Neoplasms1
Postoperative Recovery1
Thoracic Diseases1
Thoracoscopic Surgery1
Esophageal Cancer1
Healthy Volunteers1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Sir Ganga Ram Hospital2
RenJi Hospital2
Peking University First Hospital2
Beijing Tiantan Hospital2
Beijing Tsinghua Chang Gung Hospital2
Tongji Hospital2
Sedana Medical1
China-Japan Friendship Hospital1
Dan Liu1
Fudan University1
Northern Jiangsu People's Hospital1
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology1
First Affiliated Hospital of Zhejiang University1
Xi'an Aerospace General Hospital1
Affiliated Hospital of Jiaxing University1

+ 4 more sponsors in the trial list above.

04

By country register

RegisterTrialsRecruiting
Clinical trials in China229
Clinical trials in India22
Clinical trials in USA10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Propofol trials

How many clinical trials are testing Propofol?

25 current trials in our China, India and USA registers name Propofol as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Propofol trials recruiting patients?

Yes. 11 of the 25 trials are recruiting: 9 with sites in China and 2 with sites in India. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Propofol clinical trials?

Sir Ganga Ram Hospital (2), RenJi Hospital (2), Peking University First Hospital (2) and Beijing Tiantan Hospital (2), among 19 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Propofol works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Propofol works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Propofol (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.