Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: 2025 Eurostat Trade Data and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: 2025 Eurostat Trade Data and Economic Impact
Clinical Trials in Canada / NCT06408012
Recruiting Observational

An Innovative Master Platform for Clinical Trials in Mood Disorders

NCT06408012 · tracked via the Priya Life Science Canada tracker
Sponsor
St. Joseph's Healthcare Hamilton
Phase
Observational
Started
2023-10-17
Last updated
2026-07-13

Condition(s) studied

Mood DisordersDepressive DisorderBipolar and Related Disorders

Study summary

Mood disorders such as depression and bipolar disorder affect over 350 million people around the world. While several effective treatments exist, it is often difficult to match the right treatment to an individual person. Repeated efforts to find the right treatment contribute to poor functioning, low quality of life, and prolongs the time it takes to get well. Most areas of medicine are able to use 'biomarkers' or clinical tests, blood tests, or imaging to help diagnose and treat illness. The search for biomarkers in mood disorders is advancing, but one roadblock to progress is the lack of large, standardized studies of mood disorders that are needed to accurately identify biomarkers. The aim of the ENABLE platform is to provide the Canadian neuroscience community a standardized way of collecting biomarker data from individuals with a range of mood disorders symptoms. In addition, this 'master clinical trial platform' framework will provide a pool of participants who can be recruited into biomarker-based clinical trials.

Eligibility

Sex
ALL
Min age
16 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria Patients: 1. 16 years of age or older. 2. Meet criteria for bipolar or depressive disorders as defined by DSM-5. 3. Fluency in English, sufficient to complete the interviews and self-report questionnaires. Inclusion Criteria Healthy Comparison (HC) Participants: 1. 16 years of age or older. 2. No history of psychiatric disorders (according to DSM-5) or significant unstable medical conditions. 3. Fluency in English, sufficient to complete the interviews and self-report questionnaires.

Primary outcome measure(s)

  • Rate of participation in the master trial platform — 31st March 2026
    Number of participants who consent to be included in the registry

Trial sites (9)

FacilityCityRegionStatus
University of Calgary Calgary Alberta Recruiting
University of British Columbia Vancouver British Columbia Recruiting
Nova Scotia Health Authority Halifax Nova Scotia Recruiting
McMaster University Hamilton Ontario Recruiting
Queen's University Kingston Ontario Recruiting
University of Ottawa Ottawa Ontario Recruiting
University Health Network Toronto Ontario Recruiting
Centre for Addiction and Mental Health Toronto Ontario Recruiting
Ontario Shores Centre for Mental Health Sciences Whitby Ontario Recruiting

More St. Joseph's Healthcare Hamilton trials in Canada

The Effects of Weight and Nutrition Education on Weight Control Beliefs, Body Image, Self-Esteem and Eating Patterns in Undergraduate Dieters Recruiting
Non-invasive Ventilation and Dexmedetomidine in Critically Ill Adults Recruiting
Affect of Duavive on Mood & Anxiety Symptoms Recruiting
Near-Infrared Fluorescence Guided Robotic Pulmonary Segmentectomy for Early Stage Lung Cancer Recruiting
Multiprofen-CC to Reduce Pain in Hand Arthritis Recruiting

Other trials for the same condition

Accelerated vs. Conventional Theta Burst Stimulation for Late-life Depression Recruiting
A Randomized Neuroimaging Trial of Psilocybin in Depression Recruiting
Big Feelings: A Study on Children's Emotions in Therapy Recruiting
DIALOG: Understanding Disorganisation: A Language-focused Global Initiative in Psychosis Starting soon
Characterizing MyMood Patterns of Use Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06408012 on ClinicalTrials.gov ↗ ← All trials in Canada