This study is open to people with idiopathic pulmonary fibrosis (IPF) or progressive pulmonary fibrosis (PPF). They can only take part if they have completed treatment in a previous study with a medicine called nerandomilast or BI 1015550.
The goal of this study is to find out how well people with pulmonary fibrosis tolerate long- term treatment with nerandomilast. The study also tests whether nerandomilast improves lung function and prolongs the time until symptoms get worse, participants need to go to the hospital, or die.
Every participant takes nerandomilast as tablets for up to 1 year and 10 months. The participants may also continue their regular treatment for pulmonary fibrosis during the study.
Participants visit their doctors regularly. During these visits, the doctors collect information on any health problems of the participants. Participants also regularly do lung function tests.
| Facility | City | Region | Status |
|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | |
| University of Arizona | Tucson | Arizona | |
| University of Southern California | Los Angeles | California | |
| Cedars-Sinai Medical Center | Los Angeles | California | |
| University of California Los Angeles | Los Angeles | California | |
| University of California Davis | Sacramento | California | |
| National Jewish Health | Denver | Colorado | |
| Yale University School of Medicine | New Haven | Connecticut | |
| Christiana Hospital | Newark | Delaware | |
| Georgetown University | Washington D.C. | District of Columbia | |
| St. Francis Medical Institute | Clearwater | Florida | |
| University of Florida | Gainesville | Florida | |
| Clinical Research Specialists LLC - Kissimmee | Kissimmee | Florida | |
| Advanced Pulmonary Research Institute | Loxahatchee Groves | Florida | |
| Piedmont Physicians Pulmonary & Sleep Medicine of Buckhead | Atlanta | Georgia | |
| The Emory Clinic | Atlanta | Georgia | |
| Northshore University Health System | Evanston | Illinois | |
| University of Kansas Medical Center | Kansas City | Kansas | |
| Tulane Medical Center | New Orleans | Louisiana | |
| Johns Hopkins Hospital | Baltimore | Maryland | |
| Massachusetts General Hospital | Boston | Massachusetts | |
| Brigham and Women's Hospital | Boston | Massachusetts | |
| St. Elizabeth's Medical Center | Boston | Massachusetts | |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | |
| University of Michigan | Ann Arbor | Michigan | |
| Corewell Health William Beaumont University Hospital | Royal Oak | Michigan | |
| University of Minnesota | Minneapolis | Minnesota | |
| Mayo Clinic, Rochester | Rochester | Minnesota | |
| The Lung Research Center, LLC | Chesterfield | Missouri | |
| Creighton University | Omaha | Nebraska | |
| University of Nebraska Medical Center | Omaha | Nebraska | |
| Renown Regional Medical Center | Reno | Nevada | |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | |
| Northern Westchester Hospital | Mount Kisco | New York | |
| Columbia University Medical Center-New York Presbyterian Hospital | New York | New York | |
| NewYork-Presbyterian/Weill Cornell Medical Center | New York | New York | |
| Duke University Medical Center | Durham | North Carolina | |
| Southeastern Research Center-Winston Salem-69289 | Winston-Salem | North Carolina | |
| University of Cincinnati | Cincinnati | Ohio | |
| Cleveland Clinic | Cleveland | Ohio |
+ 333 more sites — see the full list on the official registry below.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06238622 on ClinicalTrials.gov ↗ ← All trials in Canada