DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy
NCT07472517 · Small Cell Lung Cancer (SCLC), Extensive-stage Small Cell Lung Cancer (ES-SCLC)
|
Phase 3 |
Recruiting |
2026-04 |
Ireland, UK, USA, China |
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
NCT06324357 · Metastatic Breast Cancer, Metastatic Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
|
Phase 1/2 |
Recruiting |
2024-06 |
UK, USA, China |
|
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
|
Phase 2 |
Recruiting |
2026-03 |
UK, USA, India, China |
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473 · Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases
|
Phase 3 |
Recruiting |
2025-07 |
Ireland, UK, USA, India, China |
|
A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)
|
Phase 1 |
Recruiting |
2023-02 |
UK, USA |
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
NCT06632457 · Metabolic Dysfunction Associated Steatohepatitis
|
Phase 3 |
Recruiting |
2024-11 |
UK, USA, India, China |
|
A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)
|
Phase 3 |
Recruiting |
2026-07 |
UK, USA, China |
|
A Study to Test How Well Different Doses of BI 3822971 Are Tolerated by People With Advanced Cancer (Solid Tumours)
|
Phase 1 |
Recruiting |
2026-09 |
China |
|
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
|
Phase 3 |
Recruiting |
2024-06 |
UK, USA, India, China |
|
A Study of BI 3810944 in Patients With Advanced Cancer
|
Phase 1 |
Recruiting |
2026-02 |
USA |
|
A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
|
Phase 3 |
Recruiting |
2026-08 |
USA, India |
|
The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis
|
Phase 3 |
Recruiting |
2025-06 |
Ireland, UK, USA, India, China |
A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well
NCT07361302 · ClinicalTrials.gov ↗ · Acute Ischemic Stroke
|
Phase 3 |
Recruiting |
2026-02 |
India, China |
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
NCT07409181 · ClinicalTrials.gov ↗ · Systemic Lupus Erythematosus
|
Phase 2 |
Recruiting |
2026-04 |
UK, USA, India, China |
|
Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations
|
Phase 2 |
Recruiting |
2024-10 |
UK, USA, China |
|
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
|
Phase 3 |
Recruiting |
2025-05 |
UK, USA, India, China |
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
NCT07220083 · ClinicalTrials.gov ↗ · Focal Segmental Glomerulosclerosis
|
Phase 3 |
Recruiting |
2026-02 |
UK, USA, India, China |
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
NCT06632444 · ClinicalTrials.gov ↗ · Metabolic Dysfunction Associated Steatohepatitis (MASH), Liver Fibrosis
|
Phase 3 |
Recruiting |
2024-10 |
UK, USA, India, China |
FIBRONEER-ACT: A Study to Test Whether Nerandomilast Helps People With Fibrosing Interstitial Lung Disease at Risk for Disease Progression
NCT07540988 · ClinicalTrials.gov ↗ · Interstitial Lung Diseases
|
Phase 3 |
Recruiting |
2026-09 |
UK, USA, China |
A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis
NCT07497087 · ClinicalTrials.gov ↗ · Systemic Sclerosis
|
Phase 3 |
Recruiting |
2026-07 |
UK, USA, India, China |
DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancers
NCT05882058 · ClinicalTrials.gov ↗ · Small Cell Lung Carcinoma, Neuroendocrine Neoplasms, Extra-pulmonary Neuroendocrine Carcinoma
|
Phase 2 |
Recruiting |
2023-10 |
UK, USA, China |
DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy
NCT07544654 · ClinicalTrials.gov ↗ · Extrapulmonary Neuroendocrine Cancer (epNEC)
|
Phase 3 |
Recruiting |
2026-07 |
UK, USA, China |
A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases
NCT06806592 · ClinicalTrials.gov ↗ · Interstitial Lung Diseases, Systemic Autoimmune Rheumatic Diseases Associated Interstitial Lung Diseases
|
Phase 3 |
Recruiting |
2025-09 |
UK, USA, China |
A Study to Test How Well Different Doses of BI 3820768 Are Tolerated by People With Advanced Cancer (Solid Tumours)
NCT07306559 · Advanced Relapsed or Refractory Germ Cell Tumours, Advanced Relapsed or Refractory Endometrial Cancer, Advanced Relapsed or Refractory Ovarian Cancer
|
Phase 1 |
Recruiting |
2026-02 |
USA |
|
A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3
|
Phase 1 |
Recruiting |
2024-01 |
USA |
|
A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems
|
Phase 1 |
Recruiting |
2025-07 |
USA |
A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis
NCT06636656 · ClinicalTrials.gov ↗ · Ulcerative Colitis
|
Phase 2 |
Recruiting |
2024-12 |
USA |
|
A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema
|
Phase 2 |
Recruiting |
2025-06 |
UK, USA, China |
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
NCT07195695 · ClinicalTrials.gov ↗ · Non-small Cell Lung Cancer
|
Phase 3 |
Recruiting |
2026-01 |
UK, USA, China |
Beamion 44: A Study to Test How Well Zongertinib is Tolerated by People With Advanced Non-small Cell Lung Cancer With HER2 Mutations When Given in Combination With Chemotherapy With or Without Pembrolizumab
NCT07486817 · ClinicalTrials.gov ↗ · Lung Cancer, Non-squamous, Non-small Cell
|
Phase 2 |
Recruiting |
2026-06 |
China |
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
NCT07107945 · ClinicalTrials.gov ↗ · Chronic Kidney Disease
|
Phase 3 |
Recruiting |
2025-12 |
UK, USA |
A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis
NCT07201922 · ClinicalTrials.gov ↗ · Familial Pulmonary Fibrosis, Interstitial Lung Abnormalities, Interstitial Lung Diseases
|
Phase 3 |
Recruiting |
2026-02 |
UK, USA |
A Study in People With Advanced Cancer to Test How Well Different Doses of BI 3819026 Are Tolerated When Taken Alone and Together With Ezabenlimab
NCT07607678 · ClinicalTrials.gov ↗ · Advanced Solid Cancer, Metastatic Solid Cancer
|
Phase 1 |
Recruiting |
2026-05 |
USA |
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
NCT07553429 · ClinicalTrials.gov ↗ · Diabetic Macular Edema
|
Phase 1/2 |
Recruiting |
2026-05 |
USA |
|
A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)
|
Phase 2 |
Recruiting |
2026-02 |
USA |
A Study to Test How BI 3000202 is Taken up in the Blood of People With and Without Liver Problems
NCT07486102 · ClinicalTrials.gov ↗ · Healthy, Hepatic Impairment
|
Phase 1 |
Recruiting |
2026-05 |
USA |
DAREON®-36: A Study to Test Obrixtamig in Combination With ZL-1310 in People With Advanced Small Cell Lung Cancer or Other Neuroendocrine Cancers
NCT07707895 · Small Cell Lung Cancer, Large Cell Neuroendocrine Lung Carcinoma, Extrapulmonary Neuroendocrine Carcinoma of Small Cell Histology
|
Phase 1/2 |
Not yet open |
2026-09 |
UK, USA, China |
A Study to Understand How Nerandomilast Works in People With Active Idiopathic Inflammatory Myopathies
NCT07789015 · ClinicalTrials.gov ↗ · Idiopathic Inflammatory Myopathies
|
Phase 3 |
Not yet open |
2026-11 |
USA, China |
Real-world Comparative Effectiveness and Safety of Jardiance in Chinese Patients With Heart Failure of Reduced Ejection Fraction
NCT07044700 · ClinicalTrials.gov ↗ · Heart Failure of Reduced Ejection Fraction (HFrEF)
|
Observational |
Not yet open |
2028-01 |
China |
A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast
NCT06238622 · Idiopathic Pulmonary Fibrosis, Progressive Pulmonary Fibrosis
|
Phase 3 |
Active, closed |
2024-05 |
Ireland, UK, USA, India, China |
|
A Long-term Study to Monitor the Health Status of People With Cystic Fibrosis Who Took Part in a Previous Study With BI 3720931 (Lenticlair™-ON)
|
Phase 1/2 |
Active, closed |
2025-05 |
UK |
|
A Study to Test Whether BI 764524 Helps People With an Eye Condition Called Diabetic Retinopathy
|
Phase 2 |
Active, closed |
2024-05 |
UK, USA |
|
A Study to Test Different Doses of BI 1701963 Alone and Combined With Trametinib in Patients With Different Types of Advanced Cancer (Solid Tumours With KRAS Mutation)
|
Phase 1 |
Active, closed |
2019-11 |
USA |
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
NCT06531824 · ClinicalTrials.gov ↗ · Kidney Disease, Chronic
|
Phase 3 |
Active, closed |
2024-08 |
UK, USA, India, China |
A Study to Test How Well BI 3000202 is Tolerated by People With Type 1 Interferonopathies
NCT06878365 · ClinicalTrials.gov ↗ · Type 1 Interferonopathies
|
Phase 1 |
Active, closed |
2025-07 |
UK, USA |
|
Clairleafᵀᴹ: A Study to Test Long-term Treatment With BI 1291583 in People With Bronchiectasis Who Took Part in a Previous Study With This Medicine
|
Phase 2 |
Active, closed |
2023-09 |
UK, USA |
A Study to Test Whether Treatment With BI 770371 in Combination With Pembrolizumab With or Without Cetuximab Helps People With Head and Neck Cancer Compared With Pembrolizumab Alone
NCT06806852 · ClinicalTrials.gov ↗ · Head and Neck Squamous Cell Carcinoma
|
Phase 1 |
Active, closed |
2025-05 |
UK, USA |
A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation
NCT04973163 · ClinicalTrials.gov ↗ · Solid Tumors, KRAS Mutation
|
Phase 1 |
Active, closed |
2021-09 |
UK, USA |
|
A Study to Test Long-term Treatment With Brigimadlin in People With Solid Tumours Who Took Part in a Previous Study With This Medicine
|
Phase 2 |
Active, closed |
2024-12 |
UK, USA, China |
Beamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment
NCT06151574 · ClinicalTrials.gov ↗ · Lung Cancer, Non-squamous, Non-small Cell
|
Phase 3 |
Active, closed |
2024-02 |
UK, USA, China |
|
A Study in People With Advanced Cancer to Test How Well Different Doses of BI 770371 Alone or in Combination With Ezabenlimab Are Tolerated
|
Phase 1 |
Active, closed |
2022-05 |
USA |
|
A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer
|
Phase 1 |
Active, closed |
2021-10 |
USA, China |
A Study in People With Overweight or Obesity to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body
NCT07407348 · ClinicalTrials.gov ↗ · Healthy, Obesity, Overweight
|
Phase 1 |
Active, closed |
2026-03 |
UK |
DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer
NCT06077500 · ClinicalTrials.gov ↗ · Small Cell Lung Carcinoma (SCLC)
|
Phase 1 |
Active, closed |
2024-02 |
USA |
DAREON™-9: A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With Small Cell Lung Cancer When Taken Together With a Single Agent Chemotherapy
NCT05990738 · ClinicalTrials.gov ↗ · Small Cell Lung Carcinoma (SCLC)
|
Phase 1 |
Active, closed |
2024-02 |
UK, USA |
A Study to Test Whether BI 3034701 Helps People to Lose Weight Who Live With Obesity or Overweight
NCT07662122 · ClinicalTrials.gov ↗ · Obesity, Overweight
|
Phase 2 |
Active, closed |
2026-06 |
UK, USA, China |
Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)
NCT04886804 · ClinicalTrials.gov ↗ · Neoplasm Metastasis, Non-Small Cell Lung Cancer
|
Phase 1 |
Active, closed |
2021-07 |
UK, USA, China |
Real-World Treatment Patterns and Outcomes in HER2-Altered Metastatic Breast Cancer Patients in the United States
NCT07342309 · ClinicalTrials.gov ↗ · Metastatic Breast Cancer
|
Observational |
Active, closed |
2025-09 |
USA |
DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers
NCT06132113 · ClinicalTrials.gov ↗ · Neuroendocrine Neoplasms
|
Phase 1 |
Active, closed |
2024-01 |
USA |
|
A Study to Test Whether Survodutide Improves How the Body Uses Energy and Breaks Down Fat in People With Obesity
|
Phase 1 |
Active, closed |
2025-03 |
USA |
A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment
NCT07036523 · ClinicalTrials.gov ↗ · Idiopathic Pulmonary Fibrosis
|
Phase 2 |
Active, closed |
2025-11 |
USA |
A Study to Test Different Doses of BI 1584862 in People With a Distinct Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy
NCT06769048 · ClinicalTrials.gov ↗ · Geographic Atrophy
|
Phase 2 |
Active, closed |
2025-01 |
USA |
A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy
NCT06722157 · ClinicalTrials.gov ↗ · Macular Degeneration, Age-related, Geographic Atrophy
|
Phase 2 |
Active, closed |
2025-01 |
USA |
A Study to Evaluate ATP150/ATP152/ATP162, VSV-GP154 and Ezabenlimab in Patients With Pancreatic Ductal Adenocarcinoma
NCT05846516 · ClinicalTrials.gov ↗ · Pancreatic Ductal Adenocarcinoma
|
Phase 1 |
Active, closed |
2023-05 |
USA |
A Study to Test Different Doses of Obrixtamig in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3
NCT04429087 · ClinicalTrials.gov ↗ · Small Cell Lung Carcinoma and Other Neuroendocrine Neoplasms Expressing DLL3
|
Phase 1 |
Active, closed |
2020-07 |
USA |