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Compound · clinical trials

Empagliflozin

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 11 trials in our India, UK, USA, China and Ireland registers that name Empagliflozin as an intervention. Synced 24 Sep 2026
11Trials tracked
9Recruiting now
7Lead sponsors
5Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards

Empagliflozin is named as a drug or biological intervention in 11 clinical trials in our India, UK, USA, China and Ireland trial registers, 9 of which are recruiting. Lead sponsors include Boehringer Ingelheim (5), Hoffmann-La Roche (1) and Colorado Prevention Center (1). Registered phases: Phase 3, Phase 4, Phase 1/2 and Not applicable. Conditions studied include Heart Failure; Diabetes Mellitus, Type 2; Hypertension.

Empagliflozin also has an approved-drug profile on this site (FDA label data): Jardiance (Empagliflozin) →
01

Clinical trials of Empagliflozin

11 trials
NCT IDStudyPhaseStatusLead sponsorRegister
NCT07322237 DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With Cirrhosis (ClinicalTrials.gov ↗)
Cirrhotic Cardiomyopathy, Empagliflozin, Cardiometabolic Risk Factors
Phase 4 Recruiting Post Graduate Institute of Medical Education and Research, Chandigarh India
NCT04381936 Randomised Evaluation of COVID-19 Therapy (ClinicalTrials.gov ↗)
Pneumonia
Phase 3 Recruiting University of Oxford India
NCT06024746 A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
Heart Failure
Phase 3 Recruiting Colorado Prevention Center India, China
NCT06424288 A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure (ClinicalTrials.gov ↗)
Heart Failure
Phase 3 Recruiting Boehringer Ingelheim UK, USA, India, China
NCT06935370 A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart (ClinicalTrials.gov ↗)
Heart Failure
Phase 3 Recruiting Boehringer Ingelheim UK, USA, India, China
NCT07064473 EASi-PROTKTโ„ข - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases
Phase 3 Recruiting Boehringer Ingelheim Ireland, UK, USA, India, China
NCT07107945 A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEYยฎ Kids) (ClinicalTrials.gov ↗)
Chronic Kidney Disease
Phase 3 Recruiting Boehringer Ingelheim UK, USA
NCT03424005 A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer (ClinicalTrials.gov ↗)
Metastatic Breast Cancer
Phase 1/2 Recruiting Hoffmann-La Roche UK, USA
NCT06095492 Effect of Empagliflozin vs Linagliptin on Glycemic Outcomes,Renal Outcomes & Body Composition in Renal Transplant Recipients With Diabetes Mellitus (ClinicalTrials.gov ↗)
Kidney Transplant; Complications, Diabetes Mellitus
Not applicable Recruiting Medanta, The Medicity, India India
NCT07775846 QUARTET-DKD: Quadruple Therapy for Type 2 Diabetic Nephropathy (ClinicalTrials.gov ↗)
Type 2 Diabetic Kidney Disease
Phase 4 Not yet open Huijie Zhang China
NCT06531824 EASi-KIDNEYโ„ข (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin) (ClinicalTrials.gov ↗)
Kidney Disease, Chronic
Phase 3 Active, closed Boehringer Ingelheim UK, USA, India, China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied

15 conditions
Condition (as registered)Trials
Heart Failure3
Diabetes Mellitus, Type 21
Hypertension1
Cardiovascular Diseases1
Kidney Disease, Chronic1
Metastatic Breast Cancer1
Chronic Kidney Disease1
Pneumonia1
Kidney Transplant; Complications1
Diabetes Mellitus1
Cirrhotic Cardiomyopathy1
Empagliflozin1
Cardiometabolic Risk Factors1
Cirrhosis1
Type 2 Diabetic Kidney Disease1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Boehringer Ingelheim5
Hoffmann-La Roche1
Colorado Prevention Center1
University of Oxford1
Medanta, The Medicity, India1
Post Graduate Institute of Medical Education and Research, Chandigarh1
Huijie Zhang1
04

Trials by country register

A trial with sites in more than one country appears in each of those registers.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Empagliflozin works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Empagliflozin (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 24 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.