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Clinical Trials in Canada / NCT06519747
Recruiting Observational

DETECTion of PeriOperative Atrial Fibrillation After Noncardiac Surgery

NCT06519747 · tracked via the Priya Life Science Canada tracker
Phase
Observational
Started
2024-10-15
Last updated
2024-11-07

Condition(s) studied

Atrial FibrillationAtrial Flutter

Investigational drug(s) / intervention(s)

Cardiac monitoring device

Cardiac monitoring device: Portable, up to 14 days of monitoring

Study summary

This is a multicentre prospective cohort study where patients will receive up to 14 days of continuous ECG monitoring by wearing a portable monitoring device, starting within 72 hours after noncardiac surgery.

Eligibility

Sex
ALL
Min age
18 Years
Max age
120 Years
Healthy volunteers
No
Inclusion Criteria: 1. Had undergone noncardiac surgery within the past 72 hours and requiring, or expected to require, at least one of the following: * an overnight hospital admission after surgery * day surgery that would result in a large enough physiological insult to be able to cause POAF. Procedures excluded include those that are conducted using local anesthesia alone, are less than 30 minutes in duration, and/or are judged to be of low physiologic insult by the local investigator. 2. Have one of the following high-risk criteria; * age 55-64 years, and having either established cardiovascular disease, recent major vascular surgery, a CHA2DS2-VASc score ≥3, or an elevated postoperative troponin level; * age 65-74 years, and having either established cardiovascular disease, recent major vascular surgery, a CHA2DS2-VASc score ≥2, or an elevated postoperative troponin level; or * age ≥75 years; 3. Provide written informed consent to participate. Exclusion Criteria: 1. History of documented chronic (i.e., non-transient) AF before noncardiac surgery; 2. Need for long-term systemic anticoagulation; 3. Ongoing need for long-term dual antiplatelet treatment; 4. Contraindication to oral anticoagulation; 5. Severe renal insufficiency; 6. Severe liver cirrhosis; 7. Acute stroke in the past 14 days; 8. Underwent cardiac surgery in the past 35 days; 9. History of nontraumatic intracranial, intraocular, or spinal bleeding; 10. Hemorrhagic disorder or bleeding diathesis; 11. Known life expectancy \<1 year due to concomitant disease; 12. Women who are pregnant, breastfeeding, or of childbearing potential not taking effective contraception; 13. Expected to be non-compliant with follow-up and/or device use; 14. Known contact allergy to monitoring device and/or its peripheral components; 15. Previously enrolled in DETECT-POAF.

Primary outcome measure(s)

Trial sites (6)

FacilityCityRegionStatus
Hamilton General Hospital Hamilton Ontario Recruiting
St. Joseph's Healthcare Hamilton Hamilton Ontario Not Yet Recruiting
Juravinski Hospital Hamilton Ontario Recruiting
London Health Sciences Centre - University Hospital London Ontario Not Yet Recruiting
Niagara Health System - St. Catharine's Site St. Catharines Ontario Not Yet Recruiting
Hôpital Fleurimont du Centre hospitalier universitaire de Sherbrooke Sherbrooke Quebec Not Yet Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06519747 on ClinicalTrials.gov ↗ ← All trials in Canada