Clinical trial register · Turkey

Clinical Trials in Adana, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Turkey and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5436 matching records held by the registry are in this view. Synced 13 Nov 2026, 03:18 UTC

5436

Studies in scope

all four open statuses

2491

Recruiting now

open to new participants

546

Lead sponsors

across recruiting studies

Top sites

Istanbul 2009 Ankara 1427 Izmir 559 Adana 380 Antalya 266

Trials with a site in Adana

Status

Study

Lead sponsor

Phase

Enrol

Sites in Turkey

Start

Not yet open

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk

NCT07900633Obesity, Overweight, Cardiovascular Diseases, Diabetes Mellitus, Type 2

DrugEloralintide

Eli Lilly and Company

Phase 3

3,000

Adana, Ankara, Antalya, Diyarbakır, Eskişehir, Istanbul, Kayseri, Kocaeli

2026-12

Not yet open

A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes and Chronic Kidney Disease Treated With Once Daily Basal Insulin Alone or in Combination With Metformin, SGLT2i, or Both

NCT07931547Type 2 Diabetes, Chronic Kidney Disease

DrugZenagamtide

Novo Nordisk A/S

Phase 3

450

Kayseri, Adana, Adapazarı/Turkiye, Afyonkarahisar, Ankara, Gaziantep, Izmir, Kartal/İstanbul

2026-11-10

Not yet open

The Effect of Bedside Yoga Intervention on Early Mobilization in Children

NCT07715487Children, Yoga Therapy

Cukurova University

Not applicable

Adana

2026-11-01

Not yet open

Virtual Reality for Anxiety and Birth Satisfaction During Elective Cesarean Section

NCT07908771Anxiety, Cesarean Section, Birth Satisfaction

Tarsus University

Not applicable

144

Adana

2026-11

Not yet open

A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or Obesity

NCT07861100Cardiovascular Risk, Obesity

DrugZenagamtide

Novo Nordisk A/S

Phase 3

8,500

Istanbul, Kayseri, Adana, Adapazarı/Turkiye, Afyonkarahisar, Ankara, Çanakkale/Türkiye, Eskişehir

2026-10-26

Not yet open

Supportive Care During Childbirth in Syrian Migrant Women

NCT07831785Childbirth

Tarsus University

Not applicable

100

Adana

2026-10-01

Not yet open

30-Second Versus Pulsation-Based Delayed Cord Clamping in Term Newborns

NCT07833059Umbilical Cord Clamping

Tarsus University

Not applicable

122

Adana

2026-10

Recruiting

Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05)

NCT07711002Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

DrugsSaruparib·Abiraterone·Darolutamide·Enzalutamide

AstraZeneca

Phase 3

1,330

Adana, Ankara, Cordaleo, Istanbul, Izmir

2026-09-15

Recruiting

Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus Osimertinib Monotherapy or Osimertinib in Combination With Platinum-based Chemotherapy for EGFRmt Non-small Cell Lung Cancer (IZABRIGHT-Lung02)

NCT07680790Non-Small Cell Lung Cancer

DrugsIza-bren·Osimertinib·Pemetrexed·Cisplatin

Bristol-Myers Squibb

Phase 3

850

Sur, Pendik, Adana, Ankara, Antalya, Istanbul, Izmir

2026-09-08

Recruiting

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

NCT07761117Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)

DrugElecoglipron

AstraZeneca

Phase 3

6,950

Adana, Ankara, Antalya, Center, Istanbul, Izmir, Kahramanmaraş, Kütahya

2026-08-24

Recruiting

AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications

NCT07797335Type 2 Diabetes, Cardiovascular Risk

DrugZenagamtide

Novo Nordisk A/S

Phase 3

1,778

Kayseri, Adana, Adana /yüreği̇r, Adapazarı/Turkiye, Afyonkarahisar, Ankara, Gaziantep, Istanbul

2026-08-24

Recruiting

Triage Performance and Physiological Predictors of Serious Illness in Febrile Children in the Pediatric Emergency Department

NCT07739004Fever, Triage, Pediatric Emergency Medicine, Serious Bacterial Infection

TC Erciyes University

Observational

3,000

Kayseri, Adana, Antalya, Eskişehir, Istanbul, Izmir, Manisa, Tokat Province

2026-07-28

Not yet open

Evaluation of Different Non-Invasive Methods in the Treatment of Dentin Hypersensitivity Associated With Non-Carious Cervical Lesions: A Split-Mouth Clinical Study

NCT07648147Non-Carious Cervical Lesions (NCCLs), Dentin Hypersensitivity

Cukurova University

Not applicable

Adana

2026-07-20

Recruiting

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus

NCT07662044Type 2 Diabetes Mellitus

DrugsElecoglipron·Dapagliflozin

AstraZeneca

Phase 3

800

Adana, Ankara, Bursa, Izmir, Kayseri, Samsun

2026-07-06

Recruiting

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin

NCT07662135Type 2 Diabetes Mellitus, Type 2 Diabetes With Chronic Kidney Disease

DrugElecoglipron

AstraZeneca

Phase 3

900

Adana, Ankara, Antalya, Bakırköy, Gaziantep, Kayseri, Yüreğir

2026-07-06

Recruiting

Blood Flow Restriction During Nordic Hamstring Exercise in Elite Adolescent Athletes

NCT07715786Healthy Volunteers (HV)

Toros University

Not applicable

Adana

2026-07-01

Recruiting

Elimination Diet Strategies and Histologic Remission in Children With Eosinophilic Gastrointestinal Disorders

NCT07779772Eosinophilic Gastrointestinal Disorders (EGID)

Cukurova University

Observational

Adana

2026-07-01

Recruiting

A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

NCT07667803Weight Management

DrugElecoglipron

AstraZeneca

Phase 3

4,500

Adana, Adapazarı, Ankara, Antalya, Istanbul

2026-06-29

Recruiting

Development of a Performance Model for Amputee Football Players

NCT07840781Cognitive Games, Sports Performance, Lower Limb Amputation

Tarsus University

Not applicable

Adana

2026-06-26

Recruiting

A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015)

NCT07554339Non-small Cell Lung Cancer

DrugsCalderasib·Durvalumab

Merck Sharp & Dohme LLC

Phase 3

310

Çankaya, Kartal, Adana, Ankara, Kayseri, Mersin, Rize

2026-06-18

Not yet open

Empowering Families in Pediatric Cardiovascular Surgery: A RAM-Based Approach

NCT07575451Congenital Heart Disease, Postoperative Care, Child Development, Roy Adaptation Model-based Nursing Empowerment Program

Cukurova University

Not applicable

Adana

2026-06-15

Recruiting

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

NCT07192952Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric)

DrugFinerenone

Bayer

Phase 3

117

Bilkent Ankara, Adana, Ankara, Istanbul, Izmir

2026-06-01

Recruiting

Nordic vs Blood Flow Restriction Nordic Exercise in Elite Female Pole Vaulters

NCT07705698Muscle Strength, Athletic Performance, Hamstring Adaptation, Sports Injury Prevention

Toros University

Not applicable

Adana

2026-05-27

Recruiting

BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease

NCT07492641HR+/HER2- Breast Cancer

DrugsBGB-43395·Ribociclib·Abemaciclib·Palbociclib

BeOne Medicines

Phase 3

1,056

Adana, Ankara, Ankara City Hospital, Istanbul, Izmir, Kocaeli, Mersin City Hospital

2026-05-22

Not yet open

Comparison of Sentinel Lymph Node Applications in Endometrial Cancer Cases Performed With Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) and Conventional Laparoscopy

NCT07583329Endometrial Adenocarcinoma, Endometrial Cancer

Cukurova University

Observational

160

Adana

2026-05-19

Not yet open

Adductor Canal Block With or Without Biceps Femoris Short Head Block in Total Knee Arthroplasty

NCT07568106Total Knee Arthroplasty

Cukurova University

Not applicable

132

Adana

2026-05-15

Recruiting

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

NCT07567001Obesity, Heart Failure

DrugNNC0487-0111

Novo Nordisk A/S

Phase 3

5,610

Adana, Adapazarı/Sakarya, Afyonkarahisar, Altınordu/Ordu, Ankara, Antalya, Bayraklı/İzmir, Bursa

2026-05-11

Recruiting

A Study to Identify and Characterize Patients With Type 2 Diabetes Mellitus for Possible Participation in Ongoing or Future Type 2 Diabetes Mellitus Clinical Studies

NCT07606066Type 2 Diabetes

AstraZeneca

Observational

2,150

Ankara, Adana, Gaziantep, Istanbul, Kayseri

2026-05-06

Recruiting

A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)

NCT07513376Non-small Cell Lung Cancer

DrugsPembrolizumab Formulated with Berahyaluronidase Alfa·Intismeran autogene

Merck Sharp & Dohme LLC

Phase 3

876

Adana, Ankara, Istanbul, Izmir, Kayseri

2026-05-04

Recruiting

Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC)

NCT07531095Small Cell Lung Cancer

DrugsZL-1310·Tarlatamab·Durvalumab

Amgen

Phase 1

160

Adana, Ankara, Izmir

2026-04-21

Recruiting

DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy

NCT07472517Small Cell Lung Cancer (SCLC), Extensive-stage Small Cell Lung Cancer (ES-SCLC)

DrugsObrixtamig·Etoposide·Atezolizumab·Carboplatin

Boehringer Ingelheim

Phase 3

670

Adana, Ankara, Atakum, Istanbul, Türkiye

2026-04-13

Recruiting

A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)

NCT07489495Carcinoma, Renal Cell

DrugsZanzalintinib·Belzutifan

Merck Sharp & Dohme LLC

Phase 3

758

Sıhhiye, Adana, Ankara, Edirne, Istanbul, Izmir

2026-04-09

Recruiting

Conventional vs Pulsed RF in Coccydynia

NCT07497269Back Pain

Adana City Training and Research Hospital

Not applicable

Adana, Ankara

2026-04-01

Recruiting

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

NCT07415044Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate, Ulcerative Colitis, Active Severe

DrugZotemtegrast

Eli Lilly and Company

Phase 2

1,431

Adana, Ankara, Antalya, Bornova, Hatay, Istanbul, İzmit, Mersin

2026-03-26

Recruiting

A Long-Term Observational Study of Patients With Fucosidosis

NCT07615400Fucosidosis

JCR Pharmaceuticals Co., Ltd.

Observational

Adana, Istanbul, Izmir

2026-03-25

Recruiting

PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease

NCT07355296Proteinuric Kidney Diseases

DrugApecotrep

Boehringer Ingelheim

Phase 2

132

Adana, Ankara, Bursa, Istanbul, İzmit, Melikgazi/Kayseri

2026-03-23

Recruiting

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

NCT07351058Obesity or Overweight, Type 2 Diabetes Mellitus

Hoffmann-La Roche

Phase 3

1,600

Istanbul, Adana, Ankara, Antalya, Izmir, Sariçam

2026-03-23

Recruiting

MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013)

NCT07431827Non-small Cell Lung Cancer

DrugsPembrolizumab Formulated with Berahyaluronidase Alfa·Calderasib

Merck Sharp & Dohme LLC

Phase 3

400

Adana, Ankara, Istanbul, Malatya, Mersin, Rize, Sakarya

2026-03-18

Recruiting

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

NCT07361497Non-small Cell Lung Cancer (NSCLC)

DrugsPumitamig·Durvalumab

Bristol-Myers Squibb

Phase 3

850

Adana, Antalya, Çankaya, Istanbul

2026-03-16

Recruiting

Entecavir Resistance-Associated Mutations in Chronic HBV Patients in Turkey (STREAM Study)

NCT07459426Hepatitis B, Chronic

Yaşar Bayındır, MD

Observational

700

Adana, Ankara, Antalya, Diyarbakır, Gaziantep, Izmir, Kocaeli, Malatya

2026-03-15

Recruiting

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

NCT07361510Non-Small Cell Lung Cancer (NSCLC)

DrugsPumitamig·Pembrolizumab

Bristol-Myers Squibb

Phase 3

750

Adana, Ankara, Antalya, Cordaleo, Çankaya, Istanbul, Izmir

2026-03-12

Recruiting

HBV Reactivation in Immunocompromised Patients (REANT STUDY)

NCT07529171HBV

Yaşar Bayındır, MD

Observational

490

Adana, Ankara, Antalya, Diyarbakır, Düzce, Gaziantep, Istanbul, Izmir

2026-03-09

Recruiting

Scapulothoracic Stabilization and Postural Training in Upper Extremity Lymphedema

NCT07697495Secondary Lymphedema

Toros University

Not applicable

Adana

2026-03-01

Recruiting

Respiratory and Relaxation Training in Lower Extremity Lymphedema

NCT07697482Lower Extremity Lymphedema

Toros University

Not applicable

Adana

2026-03-01

Recruiting

Thermal Artifact in Patients Undergoing Conization: A Clinical Study

NCT07372248Cervix Neoplasm, Cervix, Dysplasia

Saglik Bilimleri Universitesi

Not applicable

150

Adana

2026-02-23

Recruiting

To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer

NCT07368998Breast Cancer

DrugsInavolisib·Fulvestrant

Hoffmann-La Roche

Phase 2

Bağcılar, Adana, Ankara, Seyhan

2026-02-18

Not yet open

Determining the Effect of Midwife-Led Safe Infant Care Training for Pregnant Women on Awareness of Sudden Infant Death Syndrome and Home Accidents

NCT07346482Infant Death, Infant Care, Midwifery, Education

Cukurova University

Not applicable

120

Adana

2026-02-16

Recruiting

A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)

NCT07220083Focal Segmental Glomerulosclerosis

DrugApecotrep

Boehringer Ingelheim

Phase 3

286

Adana, Ankara, Battalgazi / Malatya, Bursa, Istanbul, İzmit, Melikgazi/Kayseri, Merkez / Afyonkarahisar

2026-02-16

Recruiting

The Effect on Adolescents' Cyberbullying/Cyber Victimization and Coping Skills of the Human Values-Oriented Cyberbullying Prevention Program

NCT07443748Human Values-Oriented Cyberbullying Prevention Program

Pelin Büyüksandıç Özşen

Not applicable

Adana

2026-02-13

Recruiting

Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)

NCT07224360Sickle Cell Disease

CSL Behring

Phase 2

Mezitli, Yenişehir, Adana, Ankara

2026-02-02

Recruiting

The Effect of Virtual Reality-Based Intervention on Anxiety, Stress, and Pain in Women Undergoing Colposcopy: A Randomized Controlled Trial

NCT07650422Virtual Reality-Based Intervention, Anxiety, Stress, Colposcopy

Osmaniye Korkut Ata University

Not applicable

Adana

2026-02-01

Recruiting

A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)

NCT07227597Small Cell Lung Cancer Extensive Stage

DrugsGocatamig·Ifinatamab Deruxtecan·Etoposide·Atezolizumab

Merck Sharp & Dohme LLC

Phase 1/2

170

Adana, Ankara, Istanbul

2026-01-29

Recruiting

Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations

NCT07195695Non-small Cell Lung Cancer

DrugsZongertinib·Atezolizumab·Durvalumab·Nivolumab

Boehringer Ingelheim

Phase 3

400

Adana, Ankara, Istanbul, Türkiye

2026-01-16

Recruiting

The Effect of a Transtheoretical Model-Based Educational Intervention on First-Year Nursing Students' HPV Knowledge, Health Beliefs, and Vaccination Behavior Intentions

NCT07248904Human Papillomavirus (HPV), Papillomavirus Vaccines, Health Knowledge, Attitudes, Practice, Students, Nursing

Cukurova University

Not applicable

Adana

2026-01-16

Not yet open

TENS for Pain and Sleep After Hernia Surgery

NCT07319754Inguinal Hernia, Postoperative Pain, Sleep Disturbance

Nigde Omer Halisdemir University

Not applicable

Adana

2026-01-10

Recruiting

Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

NCT07179380Pulmonary Hypertension, Interstitial Lung Disease

DrugTreprostinil Palmitil

Insmed Incorporated

Phase 3

344

Adana, Ankara, Bursa, Eskişehir, Kayseri, Kocaeli, Trabzon

2026-01-07

Recruiting

Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

NCT07222566Advanced Non-Small Cell Lung Cancer, Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC)

DrugsPF-08634404·Pembrolizumab

Pfizer

Phase 3

1,410

Istanbul, Üsküdar / İstanbul, Adana, Ankara, Diyarbakır, Gaziantep, Samsun

2026-01-06

Recruiting

A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

NCT07063745Metastatic Non-small Cell Lung Cancer With MTAP Deletion

DrugsNavlimetostat·Nab-paclitaxel·Pemetrexed·Paclitaxel

Bristol-Myers Squibb

Phase 2/3

590

Izmir, Karsiyaka, Adana, Ankara, Antalya, Bursa, Edirne, Istanbul

2026-01-02

Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

NCT07221357Untreated, Unresectable, or Metastatic Colorectal Cancer

DrugsPumitamig·Folfox·Bevacizumab

Bristol-Myers Squibb

Phase 2/3

990

Adana, Ankara, Erzurum, Istanbul, Kadiköy/Istanbul

2025-12-31

Recruiting

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

NCT07174336Breast Neoplasms, Neoplasm Metastasis

DrugsTersolisib·Exemestane·Anastrozole·Ribociclib

Eli Lilly and Company

Phase 3

800

Adana, Ankara, Aydin, Edirne, Istanbul, Izmir, Mersin

2025-12-22

Recruiting

A Study to Assess Zipalertinib Versus Placebo in Participants With Early Stage NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

NCT07128199Lung Cancer, Adjuvant, Post-surgical, EGFR

DrugZipalertinib

Taiho Oncology, Inc.

Phase 3

360

Adana, Yüreğir, Ankara, Etlik, Sur, Edirne, Gaziantep, Şehitkamil

2025-12-22

Recruiting

KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)

NCT07252739Malignant Neoplasm

DrugsCalderasib·Sacituzumab tirumotecan·Cetuximab·Keytruda

Merck Sharp & Dohme LLC

Phase 2

140

Talas, Adana, Ankara

2025-12-19

Recruiting

A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

NCT07225946Prostatic Neoplasms, Castration-Resistant

DrugsPasritamig·Prednisone/Prednisolone·Docetaxel

Janssen Research & Development, LLC

Phase 3

800

Adana, Ankara, Istanbul, Izmir

2025-12-19

Recruiting

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

NCT07218380Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Neoplasm Metastasis

DrugsVepugratinib·Pembrolizumab

Eli Lilly and Company

Phase 3

450

Adana, Adapazarı, Ankara, Antalya, Diyarbakır, Edirne, Gaziantep, Istanbul

2025-12-12

Recruiting

A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

NCT07155187Non-Small Cell Lung Cancer, c-MET

DrugsTelisotuzumab Adizutecan·Osimertinib

AbbVie

Phase 2/3

490

Adapazarı, Adana, Ankara, Istanbul, Konya, Samsun

2025-12-10

Recruiting

A Phase III Study With THIO + Cemiplimab vs Chemotherapy as 3rd Line Treatment in Advanced/Metastatic NSCLC

NCT06908304Carcinoma, Non-Small -Cell Lung

DrugsGemcitabine alone·Thiotepa·Vinorelbine·Taxotere

Maia Biotechnology

Phase 3

300

Adana, Ankara, Istanbul

2025-12-08

Active, closed

A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.

NCT07222917Chronic Kidney Disease and Hypertension

DrugBaxdrostat/dapagliflozin

AstraZeneca

Phase 2

222

Adana, Adapazarı, Kahramanmaraş, Kayseri, Kocaeli

2025-12-05

Recruiting

A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014)

NCT07209111Neoplasm Malignant

DrugsCalderasib·Cetuximab

Merck Sharp & Dohme LLC

Phase 2

150

Adana, Ankara, Istanbul

2025-12-04

Not yet open

The Effect of Gamification-Based Instructional Design Developed

NCT07207590Midwifery Student

Cukurova University

Not applicable

150

Adana

2025-12-01

Recruiting

External Oblique Intercostal Block (EOICB) for Laparoscopic Cholecystectomy

NCT07241949Postoperative Pain, Laparoscopic Cholecystectomy, Paravertebral Block, External Oblique Intercostal Plane Block

Cukurova University

Not applicable

147

Adana

2025-12-01

Recruiting

A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)

NCT07241390Atherosclerosis Cardiovascular Disease, Chronic Kidney Disease

DrugOrforglipron

Eli Lilly and Company

Phase 3

7,140

Adana, Afyonkarahisar, Ankara, Antalya, Çanakkale, Çorum, Eskişehir, Istanbul

2025-12-01

Recruiting

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

NCT07218146Small-cell Lung Cancer

DrugZL-1310

Zai Lab (Shanghai) Co., Ltd.

Phase 3

480

Çankaya, Fatih, Kadıköy, Adana, Ankara, Istanbul, Sakarya

2025-11-30

Recruiting

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

NCT07169851Nausea, Vomiting, Drug-Related Side Effects and Adverse Reactions, Neoplasms

Eli Lilly and Company

Phase 2

204

Adana, Ankara, Antalya, Bornova, Edirne, Gaziantep, Pendik, Sakarya

2025-11-28

Recruiting

A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

NCT07155174Small Cell Lung Cancer

DrugsABBV-706·Lurbinectedin·Etoposide·Atezolizumab

AbbVie

Phase 2

180

Adana, Ankara, Istanbul

2025-11-25

Recruiting

An Open-label Study of Intravenous Immunoglobulin (5%) for the Treatment of Primary Immune Thrombocytopenia

NCT07233213Primary Immune Thrombocytopenia (ITP)

Grand Shuyang Life Sciences (Chengdu) Co., Ltd.

Phase 3

Ankara, Malatya, Istanbul, Kayseri, Mersin, Antalya, Adana, Gaziantep

2025-11-24

Active, closed

Pharmacokinetic Study of QL2107 Versus Keytruda® for Adjuvant Therapy of Non-Small Cell Lung Cancer (NSCLC)

NCT07162883Carcinoma, Non-Small-Cell Lung

DrugsKeytruda·Pembrolizumab

Qilu Pharmaceutical Co., Ltd.

Phase 3

146

Yüreğir, Adana, Ankara, Diyarbakır, Istanbul, Konya, Ordu, Sakarya

2025-11-21

Recruiting

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

NCT07188805Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric)

DrugFinerenone

Bayer

Phase 3

111

Adana, Ankara, Bilkent Ankara, Istanbul, Izmir

2025-11-19

Recruiting

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

NCT07186101Ulcerative Colitis

DrugsZotemtegrast·Mirikizumab

Eli Lilly and Company

Phase 2

252

Adana, Ankara, Antalya, Eskişehir, Hatay, İzmit, Malatya, Mersin

2025-11-10

Recruiting

A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

NCT07088926Bronchiectasis With Pseudomonas Aeruginosa Colonization

DrugAZD0292

AstraZeneca

Phase 2

435

Adana, Ankara, Diyarbakır, Istanbul, Mersin, Zeytinburnu

2025-11-06

Recruiting

Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpressing Non-small Cell Lung Cancer

NCT06899126Non-small Cell Lung Cancer

DrugsTrastuzumab deruxtecan·Pemetrexed·Keytruda·Pembrolizumab

Daiichi Sankyo

Phase 3

686

Adana, Ankara, Istanbul

2025-10-24

Active, closed

A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)

NCT07076121Pancreatic Ductal Adenocarcinoma

DrugsNavlimetostat·Abraxane·Nab-paclitaxel·Gemcitabine

Bristol-Myers Squibb

Phase 2/3

470

Stanbul, Adana, Ankara, Istanbul

2025-10-23

Recruiting

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

NCT07165028Metabolic Dysfunction-Associated Steatotic Liver Disease

DrugsRetatrutide·Tirzepatide

Eli Lilly and Company

Phase 3

4,500

Adana, Ankara, Bursa, Pendik, Rize, Trabzon

2025-10-15

Recruiting

The Effect of Dose and Storage Conditions of Indocyanine Green on Efficacy and Cost in Sentinel Lymph Node Mapping in Gynecological Cancer

NCT07380698Endometrial Cancer, Vulvar Cancers, Cervical Cancer, Indocyanine Green (ICG)

Cukurova University

Observational

Adana

2025-10-03

Active, closed

A Phase I Clinical Study to Evaluate the PK Profile, Efficacy, Safety and Immunogenicity of HLX17 vs. Keytruda® in Multiple Resected Solid Tumors

NCT07160335Non-small Cell Lung Cancer, Melanoma, Renal Cell Carcinoma

DrugsUS-sourced Keytruda·Pembrolizumab

Shanghai Henlius Biotech

Phase 1

174

Adana, Ankara, Gaziantep, Istanbul, Izmir

2025-09-26

Recruiting

A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

NCT07111520Non-small Cell Lung Cancer

DrugsBNT326·Pumitamig

BioNTech SE

Phase 1/2

880

Adana, Ankara, Antalya, Istanbul, Mersin, Sakarya

2025-09-22

Not yet open

Evaluation of Clinical Wear and Surface Roughness of Partial Restorations Produced by Additive and Subtractive Manufacturing Methods: A Split-Mouth Randomized Controlled Clinical Trial

NCT07057401CAD/CAM Space Maintainer, 3D Printing, Dental Treatment, Dental Disease

Husna Selinay

Not applicable

Adana

2025-09-20

Recruiting

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

NCT07190209Chronic Obstructive Pulmonary Disease

DrugLunsekimig

Sanofi

Phase 3

942

Adana, Ankara, Gaziantep, Istanbul, Izmir, Mersin

2025-09-16

Recruiting

A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

NCT07037758Extensive Stage Small Cell Lung Cancer

DrugsEtakafusp alfa·Tarlatamab

Amgen

Phase 1

380

Adana, Ankara

2025-09-16

Recruiting

TRIMPACT: Real-World First-Line Atezolizumab Use in Stage IV NSCLC With PD-L1 ≥50%

NCT07279402NSCLC Stage IV, PD-L1 Gene Mutation, Atezolizumab, Real World Study

Antalya Training and Research Hospital

Observational

150

Adana, Afyonkarahisar, Ankara, Antalya, Aydin, Diyarbakır, Edirne, Gaziantep

2025-09-15

Recruiting

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

NCT06926868Breast Neoplasms

DrugsIza-bren·Nab-paclitaxel·Capecitabine·Gemcitabine

Bristol-Myers Squibb

Phase 2/3

600

Adana, Ankara, Istanbul

2025-09-11

Not yet open

Lidocaine, Paracetamol, and Dexmedetomidine for Rocuronium Injection Pain

NCT07169227Propofol Injection Pain, Rocuronium Injection Pain

DrugsLidocaine %2 ampoule·Paracetamol·Dexmedetomidine

Baskent University

Phase 4

170

Adana

2025-09

Recruiting

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

NCT07043400Metastatic Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma

DrugsLeucovorin·Adrucil·Tislelizumab·Capecitabine

BeOne Medicines

Phase 3

351

Adana, Ankara, Kuruköprü, Sefaköy

2025-08-27

Not yet open

Adjustment Period for Partial Crowns

NCT07051590Deep Caries Lesion of Pemanent Teeth

Ceren Sire

Not applicable

Adana

2025-08-20

Recruiting

The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease

NCT06975865Sickle Cell Disease

DrugRilzabrutinib

Sanofi

Phase 3

192

Adana, Mersin

2025-08-12

Recruiting

A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]

NCT07099898Neoplasms, Lung

DrugsRisvutatug rezetecan·Ris-Rez·Topotecan

GlaxoSmithKline

Phase 3

420

Adana, Samsun, Ankara, Diyarbakır, Istanbul, Izmir

2025-08-11

Recruiting

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

NCT06979596Malignant Neoplasm

DrugsOpevesostat·Tamoxifen·Exemestane·Letrozole

Merck Sharp & Dohme LLC

Phase 2

250

Adana, Ankara, Edirne, Istanbul

2025-08-11

Recruiting

RAdiation SEgmentectomy With REsin Microspheres (RASEREM) Study

NCT07345247Liver Cancer, Adult

Ankara University

Observational

150

Adana, Ankara, Denizli, Diyarbakır, Istanbul, Izmir, Kayseri, Kocaeli

2025-08-01

Recruiting

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

NCT06780111Esophageal Squamous Cell Carcinoma

DrugsIfinatamab Deruxtecan·Sacituzumab tirumotecan·Leucovorin·Adrucil

Merck Sharp & Dohme LLC

Phase 1/2

298

Adana, Ankara, Erzurum

2025-07-30

Active, closed

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

NCT07037433Atherosclerotic Cardiovascular Disease, Overweight, Obesity

DrugMaridebart cafraglutide

Amgen

Phase 3

12,800

Adana, Afyonkarahisar, Ankara, Antalya, Bursa, Denizli, Istanbul, Izmir

2025-07-25

Recruiting

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

NCT06757634Breast Cancer

DrugsGedatolisib·Ribociclib·Palbociclib·Letrozole

Celcuity Inc

Phase 3

1,180

Adana, Ankara, Diyarbakır, Edirne, Istanbul, İzmit, Konya, Mezitli

2025-07-24

Recruiting

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

NCT06758401Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC)

DrugsSigvotatug vedotin·Pembrolizumab

Pfizer

Phase 3

714

Istanbul, Izmir, Ankara, Adana, Antalya, Diyarbakır, İstanbul - Fatih

2025-07-23

Recruiting

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

NCT07064473Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases

DrugsVicadrostat·Dapagliflozin

Boehringer Ingelheim

Phase 3

11,800

Adana, Afyonkarahisar, Ankara, Antalya, Bursa, Edirne, Istanbul, Izmir

2025-07-22

Recruiting

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

NCT07060807Breast Neoplasms

DrugsPatritumab deruxtecan·Pegylated liposomal doxorubicin·Abraxane·Xeloda

Merck Sharp & Dohme LLC

Phase 3

1,000

Adana, Ankara, Diyarbakır, Istanbul, Mersin, Rize, Samsun

2025-07-21

Recruiting

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

NCT06997497Colon Adenocarcinoma, Rectal Adenocarcinoma

DrugsLeucovorin/levofolinate calcium·Bevacizumab biosimilar·Calderasib·Mvasi

Merck Sharp & Dohme LLC

Phase 3

477

Sıhhiye, Adana, Ankara, Diyarbakır, Istanbul, Izmir

2025-07-16

Recruiting

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

NCT06699849Sickle Cell Disease Vaso-occlusive Crisis

DrugIVIG

CSL Behring

Phase 2

Adana, Ankara, Istanbul, Mezitli-Mersin, Seyhan, Seyhan/Adana, Yenişehir

2025-07-10

Recruiting

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

NCT06863272Castration-Resistant Prostatic Cancer, Metastasis

DrugsOpevesostat·Ifinatamab Deruxtecan·Abiraterone·Enzalutamide

Merck Sharp & Dohme LLC

Phase 1/2

360

Adana, Ankara, Istanbul, Rize

2025-07-03

Recruiting

Meditation in Early Labor: Impact on Self-Efficacy and Childbirth Fear in First-Time Mothers

NCT07201220Meditation

Seyhan District Health Directorate, Adana

Not applicable

Adana, Seyhan

2025-07-01

Recruiting

Comparison of Clinical Performance of Partial Restorations Fabricated With Three-Dimensional Printer and CAD-CAM

NCT07031856Dental Caries, Dental Restoration, Permanent, Tooth Diseases

Cukurova University

Not applicable

Adana

2025-07-01

Active, closed

The Effect of the Sedo-Analgesia Protocol Applied to Intensive Care Unit Patients on Patient Outcomes

NCT07148544Neurosurgical Surgery, Sedo-analgesia, İntensive Care, Nursing Care

Cukurova University

Not applicable

Adana

2025-07-01

Recruiting

Effects of Total and Selective Caries Removal - Requiring or Avoiding Vital Pulp Therapy - on Pulp Vitality and Postoperative Pain in Deep Carious Mature Permanent Teeth: A Split-Mouth Clinical Study

NCT07041905Pulp Exposure, Dental, Deep Dental Caries

Cukurova University

Not applicable

Adana

2025-07-01

Recruiting

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

NCT06966700Breast Neoplasms, Triple Negative Breast Neoplasms, HR Low-Positive/HER2-Negative Breast Neoplasms

DrugsEpirubicin·Adriamycin·Xeloda·Paraplatin

Merck Sharp & Dohme LLC

Phase 3

2,400

Sıhhiye, Adana, Ankara, Istanbul, Kayseri, Mersin, Samsun

2025-06-30

Recruiting

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)

NCT07082725Niemann-Pick Type C Disease

DrugNizubaglustat

Azafaros B.V.

Phase 3

Adana, Çankaya, Bornova

2025-06-30

Active, closed

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of GM1 Gangliosidosis or GM2 Gangliosidosis

NCT07082543Gangliosidoses, GM2, Gangliosidosis, GM1

DrugNizubaglustat

Azafaros B.V.

Phase 3

Adana, Çankaya, Bornova

2025-06-30

Recruiting

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

NCT07054515Niemann-Pick Type C Disease, GM1 Gangliosidosis, GM2 Gangliosidosis

DrugNizubaglustat

Azafaros B.V.

Phase 3

147

Adana, Çankaya, Bornova

2025-06-30

Recruiting

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

NCT07082738Chronic Obstructive Pulmonary Disease (COPD)

AstraZeneca

Phase 2

987

Adana, Ankara, Bursa, İzmit, Kayseri, Mersin

2025-06-27

Recruiting

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

NCT07037459Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction, Obesity

DrugMaridebart cafraglutide

Amgen

Phase 3

5,056

Adana, Afyonkarahisar, Ankara, Çorum, Eskişehir, Istanbul, Izmir, Kayseri

2025-06-25

Recruiting

The Effect of the Training Program Given to Permanent Colostomy Patients on Self-efficacy

NCT06905925Stoma Colostomy, Colo-rectal Cancer

Cukurova University

Not applicable

Adana

2025-06-23

Recruiting

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

NCT06340568Endometrial Cancer

DrugsDoxorubicin·Docetaxel·Paclitaxel

BioNTech SE

Phase 3

480

Adana, Ankara, Bayraklı, Istanbul

2025-06-10

Active, closed

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With HeFH

NCT07000136Heterozygous Familial Hypercholesterolaemia

DrugAZD0780

AstraZeneca

Phase 3

473

Adana, Afyonkarahisar, Ankara, Izmir, İzmit

2025-06-10

Recruiting

Hand Massage for Physical Restraint

NCT07070505Physical Restraints, Hand Massage

Cukurova University

Not applicable

160

Adana

2025-06-10

Active, closed

C-Forward: Efficacy and Safety of BEM/RZR vs SOF/VEL in Subjects With Chronic HCV

NCT07037277HEPATITIS C VIRUS CHRONIC INFECTION, Hepatitis C, Chronic, Hepatitis C Virus Infection, Hepatitis C

DrugSofosbuvir-Velpatasvir

Atea Pharmaceuticals, Inc.

Phase 3

880

Adana, Ankara, Bursa, Denizli, Diyarbakır, Istanbul, Kayseri, Samsun

2025-06-02

Active, closed

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

NCT07000123Cardiovascular Disease

DrugAZD0780

AstraZeneca

Phase 3

3,103

Adana, Afyonkarahisar, Ankara, Eskişehir, Izmir, Kocaeli, Odunpazari, Yenimahalle

2025-05-28

Recruiting

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

NCT06787612Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer

DrugsREGN10597·Ubamatamab·Sarilumab·Fianlimab

Regeneron Pharmaceuticals

Phase 2

397

Seyhan, Altındağ, Istanbul, Bornova, Gaziantep, Adana, Ankara, Izmir

2025-05-28

Recruiting

Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I)

NCT06780098Lung Neoplasm

DrugsR-DXd·Ifinatamab Deruxtecan·Taxotere·Docetaxel

Merck Sharp & Dohme LLC

Phase 2

144

Izmir, Adana, Ankara, Istanbul

2025-05-28

Recruiting

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

NCT06901531Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma

DrugsZolbetuximab·Adrucil·Capecitabine·Oxaliplatin

Astellas Pharma Global Development, Inc.

Phase 3

500

Adana, Ankara, Bursa, Istanbul, Konya, Samsun, Van

2025-05-22

Recruiting

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

NCT06935370Heart Failure

DrugsVicadrostat·Dapagliflozin

Boehringer Ingelheim

Phase 3

4,200

Adana, Erzurum, Eskişehir, Gaziantep, Istanbul, Kütahya, Malatya, Mersin

2025-05-20

Active, closed

A Study to Test Whether Treatment With BI 770371 in Combination With Pembrolizumab With or Without Cetuximab Helps People With Head and Neck Cancer Compared With Pembrolizumab Alone

NCT06806852Head and Neck Squamous Cell Carcinoma

DrugsBI 770371·Cetuximab·Pembrolizumab

Boehringer Ingelheim

Phase 1

Adana, Ankara, Istanbul

2025-05-14

Recruiting

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

NCT06925737Prostate Cancer, Prostatic Neoplasms

DrugsIfinatamab Deruxtecan·Prednisolone·Prednisone·Docetaxel

Merck Sharp & Dohme LLC

Phase 3

1,440

Adapazarı, Adana, Ankara, Istanbul, Konya

2025-05-13

Active, closed

A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)

NCT06780085Carcinoma, Non-Small-Cell Lung

DrugsR-DXd·Ifinatamab Deruxtecan

Merck Sharp & Dohme LLC

Phase 2

Adana, Ankara, Istanbul, Izmir

2025-05-13

Recruiting

A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

NCT06499285Myelodysplastic Syndromes

DrugElritercept

Takeda

Phase 3

225

Adana, Ankara, Antalya, Mersin, Sakarya, Samsun

2025-05-06

Recruiting

A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

NCT06892548Advanced Lung Cancer

DrugsBNT324·Pumitamig

BioNTech SE

Phase 1/2

594

Adana, Ankara, Istanbul, Sakarya

2025-05-02

Recruiting

Different Hemostatic Agents Used in Partial Pulpotomy on Pulp Survival and Postoperative Pain

NCT07058727Efficacy of Hemostatic Agents, Partial Pulpotomy, Postoperative Pain

DrugsSodium Hypochlorite·Chlorhexidine

Cukurova University

Not applicable

Adana

2025-05-01

Recruiting

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

NCT06875310Carcinoma, Non-Small-Cell Lung

DrugsAdagrasib·Pemetrexed·Keytruda·Cisplatin

Mirati Therapeutics Inc.

Phase 3

630

Izmir, Karsiyaka, Adana, Ankara, Istanbul, Izmir

2025-04-24

Recruiting

A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer

NCT06827236Locally Advanced Breast Cancer, Unresectable Breast Carcinoma, Metastatic Breast Cancer

DrugPumitamig

BioNTech SE

Phase 1/2

380

Adana, Ankara, Istanbul, Izmir, Konya, Mersin

2025-04-23

Recruiting

The Effect of Heating the Intensive Care Room in the Early Postoperative Period on Patient Outcomes

NCT07137143Abdominal Surgery Complications, Hypothermia Following Anesthesia

Cukurova University

Not applicable

Adana

2025-04-20

Active, closed

The Learning Curve of a Gynecology and Obstetrics Resident Performing Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) Hysterectomy in a University Hospital

NCT07465822Abnormal Uterine Bleeding, Unspecified, Benign Gynecological Disease, Adenomyosis of Uterus, Uterine Leiomyomas

Cukurova University

Observational

Adana

2025-04-18

Recruiting

The Effect of Tele-Counseling Service on Nutrition, Exercise Attitude, and Medication Adherence After Bariatric Surgery

NCT07137117Bariatric Surgery (Sleeve Gastrectomy )

Cukurova University

Not applicable

Adana

2025-04-15

Recruiting

Clinical Study to Evaluate the Impact of the Accu-Chek SmartGuide CGM Solution on the Mean Change in Time in Range Compared With Self-Monitoring of Blood Glucose in Participants With Type 1 and Type 2 Diabetes Mellitus

NCT06704672Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus

Hoffmann-La Roche

Not applicable

270

Adana, Bakirkoy Istanbul, Basaksehir / Istanbul, Istanbul, Ümraniye / İstanbul

2025-04-14

Recruiting

A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01)

NCT06731907Non-small Cell Lung Cancer

DrugsPatritumab deruxtecan·Abraxane·Paraplatin·Taxol

Merck Sharp & Dohme LLC

Phase 2

Adana, Ankara

2025-03-30

Recruiting

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

NCT06890598Carcinoma, Non-Small-Cell Lung

DrugsOlomorasib·Durvalumab·Pembrolizumab

Eli Lilly and Company

Phase 3

700

Adana, Adapazarı, Ankara, Antalya, Edirne, Gaziantep, Istanbul, Izmir

2025-03-27

Recruiting

Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

NCT06932263Asthma

DrugTozorakimab

AstraZeneca

Phase 2

540

Adana, Ankara, Bursa, Gaziantep, Istanbul, Kayseri, Mersin

2025-03-26

Not yet open

Effects of Virtual Reality Application and Progressive Relaxation Exercise

NCT06896955Pregnancy, Exercise, Virtual Reality

Cukurova University

Not applicable

Adana

2025-03-25

Recruiting

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

NCT06878261Chronic Obstructive Pulmonary Disease (COPD)

DrugTezepelumab

AstraZeneca

Phase 3

990

Adana, Ankara, Istanbul, Kayseri, Kocaeli, Mersin

2025-03-25

Active, closed

Study of Eftilagimod Alfa (Efti) in Combination With Pembrolizumab and Chemotherapy Versus Placebo in Combination With Pembrolizumab and Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (TACTI-004)

NCT06726265Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

DrugsEfti·Pemetrexed·Keytruda·Paclitaxel

Immutep S.A.S.

Phase 3

756

Adana, Ankara, Bursa, Cevizli, Edirne, Istanbul, Sakarya

2025-03-21

Active, closed

Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)

NCT06788912Lung Neoplasm Malignant

DrugsSteroid mouthwash (dexamethasone·Acetaminophen·Ribociclib·Paraplatin

Merck Sharp & Dohme LLC

Phase 2

Adana, Ankara, Antalya, Izmir, Samsun

2025-03-20

Recruiting

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

NCT06841354Triple Negative Breast Neoplasms

DrugsAbraxane·Paraplatin·Sacituzumab tirumotecan·Taxol

Merck Sharp & Dohme LLC

Phase 3

1,000

Bornova, Adana, Ankara, Istanbul, Sakarya, Samsun

2025-03-16

Recruiting

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

NCT06677060Heart Failure

DrugBaxdrostat/dapagliflozin

AstraZeneca

Phase 3

11,300

Adana, Afyonkarahisar, Ankara, Antalya, Eskişehir, Istanbul, Izmir, Kahramanmaraş

2025-03-14

By invitation

The Effect of Clinical Pilates Training on Fatigue, Emotional State, Functional Capacity, Sleep and Quality of Life in Women With Systemic Lupus Erythematosus

NCT07394361Lupus Erythematosus, Systemic

Emir İbrahim IŞIK

Not applicable

Adana

2025-03-07

Recruiting

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

NCT06772623Non Small Cell Lung Carcinoma, c-MET

DrugsBudigalimab·Telisotuzumab Adizutecan·Pemetrexed·Cisplatin

AbbVie

Phase 1/2

252

Ankara, Adapazarı, Adana, Denizli, Istanbul, Konya, Samsun

2025-03-06

Recruiting

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

NCT06742723Chronic Kidney Disease and Hypertension

DrugBaxdrostat/dapagliflozin

AstraZeneca

Phase 3

5,000

Adana, Adapazarı, Altındağ, Ankara, Antalya, Haliliye, Kahramanmaraş, Kayseri

2025-03-03

Recruiting

Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment

NCT06841055Non-small Cell Lung Cancer

DrugsPumitamig·Docetaxel

BioNTech SE

Phase 2

Adana, Ankara, Antalya, Istanbul, Zeytinburnu

2025-03-03

By invitation

Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0

NCT06823115Acute Kidney Injury, Fluid Overload, Prematurity Complications, Risk Factors

Indiana University

Observational

8,000

Adana, Ankara, Istanbul

2025-03-01

Recruiting

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

NCT06597006Familial Hypercholesterolemia - Homozygous

DrugInclisiran

Novartis Pharmaceuticals

Phase 3

Adana, Ankara, Izmir

2025-02-28

Recruiting

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

NCT06767514Non-Small Cell Lung Cancer

DrugsIvonescimab·Pembrolizumab

Summit Therapeutics

Phase 3

780

Istanbul, Ankara, Adana, Antalya, Diyarbakır, Gaziantep, Izmir, İzmit

2025-02-27

Recruiting

Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

NCT06731478Gastric Cancer, Gastroesophageal Junction Cancer

DrugsTrastuzumab deruxtecan·Trastuzumab·Keytruda·Pembrolizumab

Daiichi Sankyo

Phase 3

726

Adana, Ankara, Diyarbakır, Erzurum, Istanbul, Izmir, Samsun

2025-02-27

Active, closed

A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With SCLC

NCT06745323Small Cell Lung Cancer (SCLC)

DrugTarlatamab

Amgen

Phase 2

252

Adana, Ankara, Istanbul, Izmir

2025-02-26

Recruiting

A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

NCT06646276Extensive-Stage Small Cell Lung Cancer

DrugsEtoposide·Atezolizumab·Nivolumab·Carboplatin

Bristol-Myers Squibb

Phase 3

530

Çiğli, Adana, Ankara, Istanbul

2025-02-25

Recruiting

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

NCT06612268Sickle Cell Disease

DrugEtavopivat

Novo Nordisk A/S

Phase 3

510

Adana, Ankara, Mersin

2025-02-17

Not yet open

The Effect of Position on Pain, Bleeding, Hematoma and Vital Signs After Transfemoral Coronary Angiography

NCT06795308Coronary Disease, Angiography

Mersin University

Not applicable

Adana

2025-02-03

Recruiting

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

NCT06712355Extensive-stage Small-cell Lung Cancer

DrugsPumitamig·Etoposide·Atezolizumab·Carboplatin

BioNTech SE

Phase 3

621

Adana, Ankara, Antalya, Edirne, Istanbul, Izmir, Kocaeli, Mamak

2025-02-03

Active, closed

Chronic Pain and Amputation: A Quality of Life Comparison

NCT06704386Chronic Pain, Amputation

Kastamonu University

Observational

Adana

2025-02-01

Recruiting

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

NCT06717347Diffuse Large B-Cell Lymphoma

DrugsRituximab Biosimilar·Zilovertamab vedotin·Riabni·Ruxience

Merck Sharp & Dohme LLC

Phase 3

1,046

Korfez Mahallesi, Suleymanpasa, Adana, Ankara, Antalya, Istanbul

2025-01-27

Not yet open

Vagus Nerve Stimulation and Labor

NCT0679235736-40 haftalık Hamile

Cukurova University

Not applicable

Adana

2025-01-25

Not yet open

Effect of Foot Massage After Coronary Angıography on Back Paın and Vıtal Sıgns

NCT06779955Coronary Angiography (CAG)

ayşenur kahveci

Not applicable

Adana

2025-01-15

Recruiting

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

NCT06609226Sickle Cell Disease, Thalassemia

Novo Nordisk A/S

Phase 3

480

Adana, Ankara, Mersin

2025-01-10

Recruiting

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer (ROSETTA Lung-02)

NCT06712316Non-small Cell Lung Cancer

DrugsPumitamig·Pemetrexed·Paclitaxel·Carboplatin

BioNTech SE

Phase 2/3

1,580

Adana, Ankara, Antalya, Diyarbakır, Gaziantep, Istanbul, Izmir, Kadıköy

2025-01-07

Active, closed

Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease

NCT06760637Breast Cancer

DrugsAtirmociclib·Ribociclib·Abemaciclib·Palbociclib

Pfizer

Phase 3

1,035

Istanbul, Izmir, Adana, Ankara, Diyarbakır, Sakarya

2025-01-06

Not yet open

Postoperative Behavioral Changes in Children.

NCT06761833Behavior Problems, Pediatrics, Pediatric Pain and Anxiety

Baskent University

Observational

260

Adana

2025-01

Active, closed

A Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB12 (Proposed Pembrolizumab Biosimilar) to Keytruda® in Non-small Cell Lung Cancer (BENITO Study)

NCT06687369Non Squamous Non Small Cell Lung Cancer

DrugsEU-sourced Keytruda·US-sourced Keytruda·Pemetrexed·Cisplatin

mAbxience Research S.L.

Phase 3

726

Adana, Alanya, Ankara, Istanbul, Izmir, Sakarya, Samsun, Tekirdağ

2024-12-30

Active, closed

A Phase 2 Study of Anvumetostat in Participants With MTAP-deleted Advanced NSCLC (MTAPESTRY 201)

NCT06593522MTAP-deleted NSCLC

DrugAnvumetostat

Amgen

Phase 2

Adana, Ankara, Istanbul

2024-12-26

Recruiting

A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)

NCT06679101Multiple Myeloma, Newly Diagnosed Multiple Myeloma

DrugsBelantamab mafodotin·Daratumumab·Lenalidomide·Dexamethasone

GlaxoSmithKline

Phase 3

520

Samsun, Kocaeli, Ankara, Adana, Sisli - Istanbul

2024-12-16

Recruiting

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

NCT06750094Colorectal Neoplasms

DrugsLeucovorin calcium/Levoleucovorin·Amivantamab·Erbitux·Avastin

Janssen Research & Development, LLC

Phase 3

700

Adana, Ankara, Antalya, Edirne, Istanbul, Konya, Sakarya

2024-12-12

Recruiting

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

NCT06597019Familial Hypercholesterolemia - Heterozygous

DrugInclisiran

Novartis Pharmaceuticals

Phase 3

Adana, Ankara, Izmir

2024-12-09

By invitation

COMPARISON OF PLAIN BLOCKS FOR POSTOPERATIVE PAIN MANAGEMENT IN GYNECOLOGICAL ABDOMINAL SURGERIES

NCT07021105Surgery With General Anesthesia, Gynecologic Surgical Procedures, Plane Block, Postoperative Pain Management

Cukurova University

Not applicable

Adana

2024-12-06

Recruiting

A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease

NCT06717698Chronic Kidney Disease

DrugSemaglutide

Novo Nordisk A/S

Phase 2

465

Kayseri, Adana, Ankara, Gaziantep, Istanbul, Izmir, Kocaeli

2024-12-02

By invitation

The Effect of TENS on Early Patient Outcomes After Total Knee Arthroplasty

NCT07155837Total Knee Replacement

Cukurova University

Not applicable

Adana

2024-12-01

Active, closed

Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)

NCT06635824PD-L1-positive, Locally Advanced (Unresectable Stage IIIB/C) or Metastatic NSCLC

DrugsDocetaxel·Pembrolizumab

Genmab

Phase 3

191

Adana, Ankara, Istanbul, Izmir

2024-11-25

Recruiting

A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

NCT06532006Gastroesophageal-junction Cancer, Monoclonal Antibody, Gastric Cancer, HER2-positive Gastric Cancer

DrugsHLX22·Trastuzumab·Capecitabine·Oxaliplatin

Shanghai Henlius Biotech

Phase 3

550

Adana, Ankara, Diyarbakır, Edirne, Erzurum, Kayseri, Kocaeli, Sakarya

2024-11-22

Active, closed

Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

NCT06596694Gastrointestinal Cancer

DrugPatritumab deruxtecan

Merck Sharp & Dohme LLC

Phase 1/2

180

Yenimahalle, Balçova, Adana, Ankara

2024-11-03

Recruiting

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

NCT06623422Carcinoma, Non-Small-Cell Lung

DrugsIntismeran autogene·Paraplatin·Taxol·Pemetrexed

Merck Sharp & Dohme LLC

Phase 3

680

Sıhhiye, Adapazarı, Tekirdağ, Adana, Ankara, Istanbul, Kayseri, Trabzon

2024-10-21

Active, closed

A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).

NCT06551324Metastatic Castrate Resistant Prostate Cancer (mCRPC)

DrugsMevrometostat·Xtandi·Taxotere·Enzalutamide

Pfizer

Phase 3

609

Cordaleo, Istanbul, Adana, Ankara

2024-10-21

Recruiting

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

NCT06662786Colorectal Neoplasms

DrugsLeucovorin calcium/Levoleucovorin·Amivantamab·Erbitux·Irinotecan

Janssen Research & Development, LLC

Phase 3

1,000

Adana, Ankara, Istanbul, Konya, Sakarya

2024-10-18

Recruiting

Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)

NCT06598306Extensive Stage Small Cell Lung Cancer

DrugTarlatamab

Amgen

Phase 1

220

Adana, Ankara, Istanbul

2024-10-07

Recruiting

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

NCT06561386Non-small Cell Lung Cancer

DrugsRelatlimab·Pemetrexed·Nivolumab·Cisplatin

Bristol-Myers Squibb

Phase 3

1,000

Adana, Ankara, Istanbul

2024-10-07

Active, closed

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

NCT06492616Breast Cancer

DrugsElacestrant·Tamoxifen·Exemestane·Anastrozole

Stemline Therapeutics, Inc.

Phase 3

4,556

Adana, Sakarya, Ankara, Kadıköy, Balçova, İzmit, Konya, Mersin

2024-09-27

Recruiting

A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease

NCT06613698Liver Diseases, Alcoholic

DrugGSK4532990

GlaxoSmithKline

Phase 2

393

Kocaeli, Diyarbakır, Adana, Istanbul

2024-09-27

Active, closed

Anvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104).

NCT06333951Thoracic Tumors, Non-small Cell Lung Cancer

DrugsAnvumetostat·Sotorasib·Pemetrexed·Paclitaxel

Amgen

Phase 1

Adana, Ankara

2024-09-17

Active, closed

Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab)

NCT06430866Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)

DrugsABP 234·Pembrolizumab

Amgen

Phase 3

163

Yenimahalle, İskender, Adana, Ankara, Bursa, Gaziantep, Istanbul, Sakarya

2024-09-12

By invitation

The Effect of Web-Based Education Specific to Sexual Health During Pregnancy on Sexual Life

NCT05954130Sexual Behavior

Cukurova University

Not applicable

Adana

2024-09-09

Active, closed

A Study to Compare ABP 234 and Keytruda® (Pembrolizumab) in Participants With Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer

NCT06311721Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer

DrugsABP 234·Keytruda·Pembrolizumab

Amgen

Phase 3

315

Seyhan, Keçiören, Yenimahalle, İskender, Atakum, Adana, Ankara, Bursa

2024-09-09

Active, closed

Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy

NCT06449222Locally Advanced Breast Cancer, Triple Negative Breast Cancer, Metastatic Triple Negative Breast Cancers

DrugsEribulin·Pumitamig·Gemcitabine·Paclitaxel

BioNTech SE

Phase 2

Adana, Adapazarı, Ankara, Istanbul

2024-08-26

Recruiting

Effect of Virtual Reality Application on Anxiety and Fear in Patients

NCT06830330Preoperative Patients, Patients Undergoing Abdominal Surgery

Cukurova University

Not applicable

Adana

2024-08-20

Recruiting

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

NCT06546670Sickle Cell Disease

Novartis Pharmaceuticals

Phase 1/2

161

Ankara, Adana

2024-08-15

Active, closed

Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy

NCT06449209Extensive-stage Small-cell Lung Cancer, Small-cell Lung Cancer

DrugsPumitamig·Topotecan·Etoposide·Paclitaxel

BioNTech SE

Phase 2

110

Adana, Ankara, Gaziantep, Istanbul, Izmir, Kocaeli, Sakarya, Tekirdağ

2024-08-05

Recruiting

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

NCT06252649Metastatic Colorectal Cancer

DrugsSotorasib·Panitumumab·Bevacizumab-awwb·Mvasi

Amgen

Phase 3

450

Adana, Ankara, Edirne, Istanbul, Izmir, Konya, Malatya

2024-07-17

Active, closed

A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemotherapy in Adult Patients With Non-Small Cell Lung Cancer That Can be Treated With Surgery

NCT06161441Resectable Non-small Cell Lung Cancer

DrugsFianlimab·Cemiplimab·Paraplatin·Taxol

Regeneron Pharmaceuticals

Phase 2

195

Adana, Bornova, Kocaeli, Sakarya, Konya, Kurupelit, Gaziantep, Ankara

2024-07-16

Recruiting

Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

NCT06393374Triple-Negative Breast Cancer

DrugsXeloda·Sacituzumab tirumotecan·Keytruda·Capecitabine

Merck Sharp & Dohme LLC

Phase 3

1,530

Adana, Ankara, Istanbul, Samsun

2024-06-24

Recruiting

Cera™ Vascular Plug System Post-Market Clinical Follow-Up

NCT06099015Aneurysm, Endoleak, Pulmonary Arteriovenous Malformation, Portal Hypertension

Lifetech Scientific (Shenzhen) Co., Ltd.

Observational

132

Adana, Ankara

2024-06-21

Recruiting

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

NCT06424288Heart Failure

DrugsVicadrostat·Dapagliflozin

Boehringer Ingelheim

Phase 3

6,712

Adana, Afyonkarahisar, Ankara, Elâzığ, Erzurum, Eskişehir, Gaziantep, Istanbul

2024-06-17

Active, closed

Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)

NCT06305754Non-small Cell Lung Cancer (NSCLC)

DrugsSteroid mouthwash (dexamethasone·Acetaminophen·Sacituzumab tirumotecan·Pemetrexed

Merck Sharp & Dohme LLC

Phase 3

550

Adana, Ankara, Izmir

2024-06-11

Active, closed

A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)

NCT06472076Lung Cancer, Non-Small Cell

DrugsBelrestotug·Dostarlimab·Pembrolizumab

GlaxoSmithKline

Phase 3

Adana, Ankara

2024-06-10

Recruiting

Metabolic Liver Disease in Newly Diagnosed People Living With HIV (MASHIV-TR)

NCT07737340HIV Infections, Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) & Steatohepatitis (MASH), Fatty Liver

Yaşar Bayındır, MD

Observational

411

Ankara, Adana, Antalya, Diyarbakır, Gaziantep, Istanbul, Izmir, Kocaeli

2024-06-01

Recruiting

Cukurova Score Validation Study

NCT06378905Epithelial Ovarian Cancer, Primary Cytoreduction

Cukurova University

Observational

130

Adana

2024-05-30

Recruiting

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

NCT06345729Non-small Cell Lung Cancer

DrugsCalderasib·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

348

Balçova, Bornova, Adana, Ankara, Istanbul, Sakarya

2024-05-24

Active, closed

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

NCT06353386Prostatic Neoplasms, Castration-Resistant

DrugsFludrocortisone acetate·Opevesostat·Cabazitaxel·Taxotere

Merck Sharp & Dohme LLC

Phase 1/2

220

Adana, Ankara, Istanbul

2024-05-20

Active, closed

A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015)

NCT06356311Gastroesophageal Cancer

DrugsTrifluridine/Tipiracil·Sacituzumab tirumotecan·Irinotecan·Docetaxel

Merck Sharp & Dohme LLC

Phase 3

473

Adana, Ankara, Diyarbakır, Erzurum, Istanbul, Samsun, Van

2024-05-03

Recruiting

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

NCT06319820Non-Muscle Invasive Bladder Neoplasms

DrugGemcitabine

Janssen Research & Development, LLC

Phase 3

641

?zmir, Adana, Ankara, Istanbul

2024-04-18

Recruiting

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

NCT06312176Breast Neoplasms

DrugsLiposomal doxorubicin·Abraxane·Xeloda·Sacituzumab tirumotecan

Merck Sharp & Dohme LLC

Phase 3

1,200

Yenimahalle, Stanbul, Adana, Ankara, Istanbul, Samsun

2024-04-14

Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

NCT06307652Heart Failure and Impaired Kidney Function

AstraZeneca

Phase 3

3,850

Adana, Ankara, Antalya, Bursa, Center, Dinar, Eskişehir, Istanbul

2024-04-12

By invitation

The Effect of Complex Decongestıve Therapy on Oxıdatıve Stress and Antıoxıdants

NCT06572098What Are the Effects of Lymphedema Treatment

Baskent University

Not applicable

Adana

2024-04-03

Recruiting

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

NCT06312137Non Small Cell Lung Cancer

DrugsSacituzumab tirumotecan·Pemetrexed·Gemcitabine·Paclitaxel

Merck Sharp & Dohme LLC

Phase 3

780

Korfez Mahallesi, Adana, Ankara, Istanbul, Kayseri

2024-04-03

Active, closed

A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

NCT06329401Pulmonary Fibrosis, Progressive Pulmonary Fibrosis, Pulmonary Fibrosis Secondary to Systemic Sclerosis, Pulmonary Fibrosis, Interstitial Lung Disease

DrugPirfenidone

Avalyn Pharma Inc.

Phase 2

398

Bornova, Adana, Ankara

2024-04-03

Active, closed

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

NCT06200207Heart Failure, Systemic Inflammation

DrugZiltivekimab

Novo Nordisk A/S

Phase 3

673

Eskişehir, Adana, Afyonkarahisar, Ankara, Bursa, Edirne, Istanbul, Kayseri

2024-04-01

Active, closed

A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.

NCT06268873Chronic Kidney Disease and Hypertension

DrugBaxdrostat/dapagliflozin

AstraZeneca

Phase 3

2,554

Adana, Adapazarı, Afyonkarahisar, Ankara, Antalya, Bursa, Istanbul, Kahramanmaraş

2024-03-29

Recruiting

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

NCT06318169Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

DrugPegozafermin

Hoffmann-La Roche

Phase 3

1,350

Adana, Ankara, Bursa, Center, Fatih, Gaziantep, Istanbul, Izmir

2024-03-13

Active, closed

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

NCT05827081Early Breast Cancer

DrugsLeuprolide·Goserelin·Exemestane·Ribociclib

Novartis Pharmaceuticals

Phase 3

1,466

Sakarya, Ankara, Istanbul, Izmir, Denizli, Antalya, Diyarbakır, Adana

2024-02-28

Recruiting

A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

NCT06161025Solid Cancer

DrugsR-DXd·Topotecan·Paclitaxel

Daiichi Sankyo

Phase 2/3

860

Adana, Istanbul

2024-02-27

Recruiting

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

NCT06283966COPD (Chronic Obstructive Pulmonary Disease)

AstraZeneca

Phase 3

5,250

Adana, Afyonkarahisar, Antalya, Bursa, Çanakkale, Çankaya, Isparta, Istanbul

2024-02-21

Active, closed

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib

NCT06120140Carcinoma, Non-Small-Cell Lung

DrugsClobetasol·Clindamycin·Chlorhexidine·Minocycline

Janssen Research & Development, LLC

Phase 2

305

Adana, Ankara, Istanbul, Izmir, Samsun

2024-02-16

Active, closed

A Study to Test an Oral Medicine, Belumosudil, in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease.

NCT06143891Chronic Graft Versus Host Disease

DrugsBelumosudil·Prednisolone·Prednisone

Sanofi

Phase 3

260

Adana, Ankara, Istanbul, Izmir

2024-01-23

Active, closed

A Study of DB-1303/BNT323 vs Investigator's Choice Chemotherapy in HER2-Low, Hormone Receptor Positive Metastatic Breast Cancer (DYNASTY-Breast02)

NCT06018337Metastatic Breast Cancer

DrugsDB-1303/BNT323·Nab-paclitaxel·Capecitabine·Paclitaxel

DualityBio Inc.

Phase 3

541

Adana, Ankara, Diyarbakır, Istanbul, Izmir, Mersin, Samsun

2024-01-18

Active, closed

A Study to Compare the Pharmacokinetics, Efficacy, Safety, and Immunogenicity of Pembrolizumab (SB27, EU Sourced Keytruda, and US Sourced Keytruda) in Subjects With Stage II-IIIA NSCLC Following Complete Resection and Adjuvant Platinum-based Chemotherapy

NCT06268613Non-small Cell Lung Cancer Stage II, Non-small Cell Lung Cancer Stage IIIA

DrugsEU-sourced Keytruda·US-sourced Keytruda·Pembrolizumab

Samsung Bioepis Co., Ltd.

Phase 1

163

Adana, Ankara, Istanbul, Izmir

2024-01-16

Active, closed

The Effect of Acupressure on Dyspnea and Anxiety Levels

NCT06752915COPD (Chronic Obstructive Pulmonary Disease)

ÇİĞDEM ERGİN

Not applicable

Adana

2024-01-15

Recruiting

A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s)

NCT06174987Advanced Cancer, Metastatic Cancer

DrugTrastuzumab deruxtecan

Daiichi Sankyo

Phase 3

Adana, Ankara, Antalya, Diyarbakır, Istanbul, Tekirdağ

2024-01-05

Recruiting

Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

NCT06136624Prostate Cancer Metastatic

DrugsFludrocortisone acetate·Opevesostat·Zytiga·Hydrocortisone

Merck Sharp & Dohme LLC

Phase 3

1,310

Adana, Ankara, Istanbul, Samsun

2023-12-31

By invitation

The Effect of Manual Lymph Drainage in Fibromyalgia Patients

NCT06571565Fibromyalgia, Oxidative Stress

Baskent University

Early Phase 1

Adana

2023-12-27

Active, closed

A Study of Participant Reported Preference for Subcutaneous Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) Over Intravenous Pembrolizumab (MK-3475) Formulation in Multiple Tumor Types (MK-3475A-F11)

NCT06099782Non-Small Cell Lung Cancer, Renal Cell Carcinoma, Melanoma

Drugs) Berahyaluronidase alfa·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 2

147

Adana, Ankara, Izmir

2023-12-26

Active, closed

A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3)

NCT06140836Carcinoma, Non-Small-Cell Lung

DrugsRepotrectinib·Crizotinib

Bristol-Myers Squibb

Phase 3

190

Yenimahalle, Adana, Ankara, Istanbul, Sakarya

2023-12-21

Recruiting

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

NCT06119581Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

DrugsOlomorasib·Pemetrexed·Cisplatin·Carboplatin

Eli Lilly and Company

Phase 3

1,264

Adana, Ankara, Antalya, Bursa, Diyarbakır, Istanbul, Izmir, Kocaeli

2023-12-21

Recruiting

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

NCT06136650Metastatic Castration-resistant Prostate Cancer (mCRPC), Prostatic Neoplasms

DrugsFludrocortisone acetate·Opevesostat·Prednisone Acetate·Zytiga

Merck Sharp & Dohme LLC

Phase 3

1,314

Adana, Ankara, Istanbul, Izmir, Samsun

2023-12-18

Active, closed

REZILIENT3 (REsearching ZIpaLertinib In Egfr Non-small Cell Lung Cancer Tumors)

NCT05973773Advanced or Metastatic NSCLS With Exon 20 Insertion Mutation

DrugZipalertinib

Taiho Oncology, Inc.

Phase 3

285

Adana, Ankara, Çankaya, Edirne, Etlik, Istanbul

2023-12-18

Recruiting

Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

NCT06170788Non-small Cell Lung Cancer (NSCLC)

DrugsSacituzumab tirumotecan·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

614

Stanbul, Bornova, Talas, Adana, Ankara, Denizli, Istanbul, Samsun

2023-12-15

Recruiting

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

NCT05920356Non-Small Cell Lung Cancer (NSCLC)

DrugsSotorasib·Pembrolizumab

Amgen

Phase 3

750

Adana, Ankara, Antalya, Aydin, Denizli, Istanbul, Izmir, Samsun

2023-11-16

Active, closed

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

NCT06074588Non-small Cell Lung Cancer (NSCLC)

DrugsTaxotere·Sacituzumab tirumotecan·Pemetrexed·Docetaxel

Merck Sharp & Dohme LLC

Phase 3

556

Stanbul, Bornova, Adana, Ankara, Istanbul

2023-11-12

Active, closed

A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma

NCT06054555Melanoma

DrugsOpdivo·Nivolumab

Amgen

Phase 3

633

Yenimahalle/Ankara, Kadıköy, Adana, Ankara, Bursa, Gaziantep, Istanbul, Izmir

2023-11-02

Active, closed

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

NCT06008756Arteriosclerosis, Hypercholesterolaemia

DrugEnlicitide Decanoate

Merck Sharp & Dohme LLC

Phase 3

14,550

Altindağ, Bornova, Cordaleo, Melikgazi, Adana, Ankara, Antalya, Çanakkale

2023-10-09

Active, closed

To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

NCT06072131Peripheral T Cell Lymphoma

DrugsBelinostat·Pralatrexate·CHOP·Prednisone

Acrotech Biopharma Inc.

Phase 3

504

Altındağ, Çankaya, Yenimahalle, Şişli, Adana, Bornova

2023-10-04

Recruiting

Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)

NCT06079671Locally Advanced Cervical Cancer

DrugVolrustomig

AstraZeneca

Phase 3

800

Adana, Ankara, Cordaleo, Istanbul

2023-09-22

Active, closed

A Study of Investigational Tirzepatide (LY3298176) Doses in Participants With Type 2 Diabetes and Obesity

NCT06037252Type 2 Diabetes, Obesity

DrugTirzepatide

Eli Lilly and Company

Phase 2

414

Kadıköy, Adana, Antalya, Bursa, Diyarbakır, Gaziantep, Istanbul, Samsun

2023-09-21

By invitation

An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp Alfa (DNL310) in Participants With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E-0007

NCT06075537Mucopolysaccharidosis II

DrugTividenofusp alfa

Denali Therapeutics Inc.

Phase 2/3

Adana, Ankara

2023-09-20

Active, closed

A Study Evaluating Atezolizumab and Bevacizumab, With or Without Tiragolumab, in Participants With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) (IMbrave152)

NCT05904886Hepatocellular Carcinoma

DrugsTiragolumab·Tecentriq·Avastin·Atezolizumab

Hoffmann-La Roche

Phase 3

687

Adana, Ankara, Edirne, Kar?iyaka

2023-09-14

Recruiting

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

NCT06051617Primary Biliary Cholangitis

DrugSeladelpar

Gilead Sciences

Phase 3

402

Adana, Ankara, Gaziantep, Görükle, Izmir, Karabağlar, Kocaeli, Mersin

2023-09-07

Recruiting

A Multicenter Selective Screening Study to Investigate the Frequency of Neuronal Ceroid Lipofuxinosis Type 2 (CLN2)

NCT06128226Neuronal Ceroid Lipofuxinosis Type2 (CLN2)

Nadir Hastalıkları Araştırma Derneği

Observational

750

Adana, Batman, Diyarbakır, Elâzığ, Gaziantep, Hatay, Kahramanmaraş, Malatya

2023-09-06

Active, closed

A Trial to Learn How the Combination of Fianlimab With Cemiplimab and Chemotherapy Works Compared With Cemiplimab and Chemotherapy for Treating Adult Patients With Advanced Non-small Cell Lung Cancer

NCT05800015Non-small Cell Lung Cancer

DrugsFianlimab·Cemiplimab·Paraplatin·Pemetrexed

Regeneron Pharmaceuticals

Phase 2/3

160

Adana

2023-08-08

Recruiting

A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.

NCT05967689Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations

DrugZipalertinib

Taiho Oncology, Inc.

Phase 2

220

Esenyurt, Adana, Edirne, Istanbul

2023-07-31

Active, closed

24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up

NCT05677451Chronic Spontaneous Urticaria

DrugRemibrutinib

Novartis Pharmaceuticals

Phase 3

100

Istanbul, Ankara, Adana

2023-07-11

Active, closed

A Study to Learn if a Combination of Fianlimab and Cemiplimab Versus Cemiplimab Alone is More Effective for Adult Participants With Advanced Non-Small Cell Lung Cancer (NSCLC)

NCT05785767Advanced Non-Small Cell Lung Cancer

DrugsFianlimab·Cemiplimab

Regeneron Pharmaceuticals

Phase 2/3

149

Adana, Altındağ, Istanbul, Bursa, Pendik, Bornova, Kocaeli, Konya

2023-06-30

Recruiting

A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

NCT05878769Chronic Obstructive Pulmonary Disease

Hoffmann-La Roche

Phase 3

2,000

Adana, Kirikkale, Rize Merkez

2023-06-28

Active, closed

ONC-392 Versus Docetaxel in Metastatic NSCLC That Progressed on PD-1/PD-L1 Inhibitors

NCT05671510Non Small Cell Lung Cancer

DrugsGotistobart·Taxotere·Docetaxel

OncoC4, Inc.

Phase 3

630

Adana, Ankara, Antalya, Edirne, Fatih, Istanbul, Izmir

2023-06-28

Active, closed

A Study of Combination Therapy With Amivantamab and Cetrelimab in Participants With Metastatic Non-small Cell Lung Cancer

NCT05908734Carcinoma, Non-Small-Cell Lung

DrugsCetrelimab·Amivantamab

Janssen Research & Development, LLC

Phase 1/2

Adana, Ankara, Istanbul, Izmir, Sakarya

2023-05-18

Recruiting

A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)

NCT05319730Esophageal Squamous Cell Carcinoma

DrugsMK-4830·Steroid mouthwash (dexamethasone·Acetaminophen·Sacituzumab tirumotecan

Merck Sharp & Dohme LLC

Phase 1/2

230

Adana, Ankara, Erzurum, Istanbul, Izmir

2023-05-16

Active, closed

A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma

NCT05757102Asthma

DrugFF/UMEC/VI

GlaxoSmithKline

Phase 3

138

Adana, Antalya, Istanbul

2023-04-24

Active, closed

A Trial to Learn How the Cancer Vaccine BNT116 in Combination With Cemiplimab Works and How Safe the Combination is in Adults With Advanced Non-small Cell Lung Cancer (EMPOWERVAX Lung 1)

NCT05557591Advanced Non-Small Cell Lung Cancer

DrugsBNT116·Cemiplimab

Regeneron Pharmaceuticals

Phase 2

Adana, Yüreğir, Kadıköy, Bornova, Ankara, Istanbul, Izmir

2023-04-21

Active, closed

A Study of SKB264 (MK-2870; Sac-TMT) for the Treatment of Participants With Advanced or Metastatic Non-small Cell Lung Cancer (SKB264-II-04) (MK-2870-003)

NCT05816252Non-small Cell Lung Cancer

DrugsSacituzumab tirumotecan·Osimertinib·Carboplatin·Pembrolizumab

Klus Pharma Inc.

Phase 2

356

Adana, Ankara

2023-04-19

Active, closed

Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma

NCT05611931Endometrial Cancer

DrugSelinexor

Karyopharm Therapeutics Inc

Phase 3

257

Çankaya, Adana, Ankara, Istanbul

2023-04-18

Active, closed

A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer

NCT05645692Urothelial Cancer

DrugsTobemstomig·Tiragolumab·Atezolizumab

Hoffmann-La Roche

Phase 2

204

Adana, Ankara, Edirne, Izmir, Kadiköy

2023-04-13

Active, closed

A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission

NCT05622708Non-radiographic Axial Spondyloarthritis

DrugSecukinumab

Novartis Pharmaceuticals

Phase 4

240

Adana, Konya

2023-03-28

Active, closed

Study of Novel Treatment Combinations in Patients With Lung Cancer

NCT05633667Lung Cancer, Advanced or Metastatic Non-Small-Cell Lung Cancer, Resectable Non-Small-Cell Lung Cancer

DrugsDomvanalimab·Zimberelimab·Sacituzumab Govitecan·Nab-paclitaxel

Gilead Sciences

Phase 2

192

Adana, Ankara, Atakum, Diyarbakır, Konya, Meram Konya, Yenimahalle

2023-03-16

Active, closed

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

NCT05445778Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer

DrugsMirvetuximab Soravtansine·Bevacizumab

AbbVie

Phase 3

520

Adana, Ankara

2023-03-15

Active, closed

A Study to Learn About a New Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People Who Have Advanced Metastatic Breast Cancer

NCT05654623Advanced Breast Cancer

DrugsVepdegestrant·Fulvestrant

Pfizer

Phase 3

624

Altindağ, Istanbul, Izmir, Adana, Ankara, Antalya, Edirne, Samsun

2023-03-03

Active, closed

REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels

NCT05669755Cardiovascular Disease

DrugsCagrilintide·Semaglutide

Novo Nordisk A/S

Phase 3

7,101

Ankara, Istanbul, Eskişehir, Bursa, Adana, Afyonkarahisar, Edirne, Izmir

2023-03-01

Active, closed

A Study to Determine the Effect of Triheptanoin Compared With Even-Chain MCT on MCEs in Pediatric Patients With LC-FAOD

NCT05933200Long-chain Fatty Acid Oxidation Disorders (LC-FAOD)

Ultragenyx Pharmaceutical Inc

Phase 3

Adana, Ankara, Bornova-İzmir, Istanbul

2023-02-28

Active, closed

A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A

NCT05685238Haemophilia A, Haemophilia A With Inhibitors

Novo Nordisk A/S

Phase 3

451

Ankara, Capa-ISTANBUL, Antalya, Adana, Bornova-IZMIR, Edirne

2023-02-13

Recruiting

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies

NCT05682378Heterozygous or Homozygous Familial Hypercholesterolemia

DrugInclisiran

Novartis Pharmaceuticals

Phase 3

195

Istanbul, Adana, Ankara, Izmir

2023-02-10

Active, closed

A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants With Severe Hemophilia

NCT05662319Hemophilia

DrugsAntithrombin·Clotting factor concentrates·Fitusiran

Sanofi

Phase 3

Adana, Akdeniz, Çapa, Izmir

2023-02-01

Active, closed

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma

NCT05748600Eosinophilic Asthma, Asthma; Eosinophilic, Asthma Attack

DrugDexpramipexole Dihydrochloride

Areteia Therapeutics

Phase 3

600

Adana, Ankara, Antalya, Bornova, Center, Istanbul, Konak, Mersin

2023-01-30

Active, closed

Study of XL092 + Nivolumab vs Sunitinib in Subjects With Advanced or Metastatic Non-Clear Cell Renal Cell Carcinoma

NCT05678673Non-Clear Cell Renal Cell Carcinoma

DrugsSunitinib Malate·Zanzalintinib·Sunitinib·Opdivo

Exelixis

Phase 3

317

Adana, Ankara, Istanbul, Izmir

2023-01-01

Active, closed

Phase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic Alterations

NCT05687266NSCLC

DrugsDato-DXd·Durvalumab·Pemetrexed·Paclitaxel

AstraZeneca

Phase 3

1,350

Adana, Ankara, Edirne, Istanbul, Izmir

2022-12-29

Recruiting

Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B Respectively

NCT05568719Hemophilia A, Hemophilia B

Pfizer

Phase 3

173

Izmir, Adana, Gaziantep, Istanbul

2022-12-28

Recruiting

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

NCT05712200Atrial Fibrillation (AF)

DrugAbelacimab

Anthos Therapeutics, Inc.

Phase 3

2,500

Adana, Istanbul, Pendik, Izmir, Ankara, Antalya, Bursa, Diyarbakır

2022-12-27

Recruiting

A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

NCT05611801Hemophilia A, Hemophilia B

DrugMarstacimab

Pfizer

Phase 3

100

Adana, Ankara, Istanbul, Izmir, Kayseri, Melikgazi, Samsun

2022-12-09

Recruiting

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

NCT05457283Chronic Kidney Disease, Proteinuria, Children

DrugFinerenone

Bayer

Phase 3

100

Adana, Ankara, Istanbul

2022-11-08

Active, closed

A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight

NCT05567796Obesity

DrugsCagrilintide·Semaglutide

Novo Nordisk A/S

Phase 3

3,400

Ankara, Sultangazi, Adana, Antalya, Hatay, Istanbul, Sivas

2022-11-01

Active, closed

A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity

NCT05556512Obesity, Overweight

DrugTirzepatide

Eli Lilly and Company

Phase 3

15,374

Adana, Ankara, Antalya, Aydin, Balçova, Bornova, Denizli, Gaziantep

2022-10-11

Active, closed

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

NCT05514054Breast Neoplasms

DrugsImlunestrant·Tamoxifen·Exemestane·Anastrozole

Eli Lilly and Company

Phase 3

8,000

Adana, Adapazarı, Altindağ, Ankara, Antalya, Bursa, Diyarbakır, Edirne

2022-10-04

Recruiting

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

NCT05386108Breast Neoplasms, Brain Neoplasms, Neoplasms by Site, Neoplasms

DrugsElacestrant·Abemaciclib

Stemline Therapeutics, Inc.

Phase 1/2

Adana, Ankara, Bornova, Istanbul

2022-08-31

Active, closed

A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer

NCT05388669Advanced or Metastatic Non-small Cell Lung Cancer

DrugsLazertinib·Amivantamab

Janssen Research & Development, LLC

Phase 3

418

Adana, Ankara, Edirne, Istanbul, Izmir, Samsun

2022-08-05

Active, closed

Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment

NCT05261399Carcinoma, Non-Small-Cell Lung

DrugsSavolitinib·Tagrisso·Osimertinib·Pemetrexed

AstraZeneca

Phase 3

341

Adana, Ankara, Edirne, Istanbul, Izmir

2022-08-03

Active, closed

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

NCT05382286Triple Negative Breast Cancer, PD-L1 Positive

DrugsAbraxane·Sacituzumab Govitecan·Taxol·Nab-paclitaxel

Gilead Sciences

Phase 3

443

Adana, Ankara, Edirne, Istanbul, Izmir, Sariyer, Şişli

2022-07-25

Active, closed

A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric and Young Adult Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II)

NCT05371613Mucopolysaccharidosis II

DrugsIdursulfase·Tividenofusp alfa

Denali Therapeutics Inc.

Phase 2/3

Adana, Çankaya

2022-07-21

Active, closed

Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

NCT05382299Triple Negative Breast Cancer, PD-L1 Negative

DrugsAbraxane·Sacituzumab Govitecan·Nab-paclitaxel·Gemcitabine

Gilead Sciences

Phase 3

623

Adana, Ankara, Edirne, Istanbul, Izmir, Sariyer

2022-07-20

Active, closed

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

NCT05296798Locally Advanced or Metastatic Breast Cancer

DrugsPhesgo·Giredestrant·Pertuzumab·Trastuzumab

Hoffmann-La Roche

Phase 3

922

Adana, Ankara, Diyarbakır, Edirne, Erzurum, Istanbul, Izmir, İzmit

2022-07-18

Recruiting

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

NCT05142189Non-Small Cell Lung Cancer

DrugsBNT116·Gotistobart·Cemiplimab·Osimertinib

BioNTech SE

Phase 1

320

Adana, Ankara, Istanbul, Izmir

2022-06-17

Active, closed

IO102-IO103 in Combination With Pembrolizumab Versus Pembrolizumab Alone in Advanced Melanoma (IOB-013 / KN-D18)

NCT05155254Metastatic Melanoma, Unresectable Melanoma

DrugsIO102-IO103·Pembrolizumab

IO Biotech

Phase 3

407

Adana, Ankara, Antalya, Bornova, Istanbul

2022-05-17

Active, closed

Study to Evaluate the Efficacy and Safety of Venglustat in Adult and Pediatric Patients With Gaucher Disease Type 3

NCT05222906Gaucher's Disease Type III

DrugsImiglucerase·Venglustat

Sanofi

Phase 3

Adana, Ankara, Istanbul

2022-04-18

Active, closed

A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer)

NCT05288166Prostatic Neoplasms, Neoplasm Metastasis, Urogenital Neoplasms, Physiological Effects of Drugs

DrugsAbiraterone·Abemaciclib·Prednisolone·Prednisone

Eli Lilly and Company

Phase 3

925

Stanbul, Izmir, Karsiyaka, Adana, Ankara, Diyarbakır, Edirne, Istanbul, Malatya

2022-04-14

Active, closed

A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

NCT05196035Chronic Kidney Disease, Proteinuria

DrugFinerenone

Bayer

Phase 3

219

Ankara, Adana, Istanbul

2022-03-28

Recruiting

A Study to Assess Disease Activity and Adverse Events of Intravenous (IV) Telisotuzumab Vedotin Compared to IV Docetaxel in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

NCT04928846Non Small Cell Lung Cancer, c-MET

DrugsTelisotuzumab vedotin·Docetaxel

AbbVie

Phase 3

768

Çankaya, Cordaleo, Adana, Ankara, Battalgazi/malatya, Bursa, Diyarbakır, Istanbul

2022-03-25

Active, closed

Study of Capivasertib + Docetaxel vs Placebo + Docetaxel as Treatment for Metastatic Castration Resistant Prostate Cancer (mCRPC)

NCT05348577Prostate Cancer

DrugsCapivasertib·Docetaxel

AstraZeneca

Phase 3

1,035

Adana, Edirne, Izmir, Şahinbey, Yüreğir

2022-03-25

Active, closed

Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008)

NCT05224141Small Cell Lung Carcinoma

DrugsPembrolizumab/Vibostolimab·Tecentriq·Paraplatin·Etoposide

Merck Sharp & Dohme LLC

Phase 3

460

Bornova, Adana, Ankara, Istanbul, Izmir

2022-03-24

Active, closed

A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors

NCT05135559Haemophilia A and B With and Without Inhibitors

DrugConcizumab

Novo Nordisk A/S

Phase 3

153

Ankara, Adana, Izmir, Samsun

2022-03-24

Active, closed

A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)

NCT05239728Carcinoma, Renal Cell

DrugsBelzutifan·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

1,800

Istanbul- Fatih, Adana, Ankara, Istanbul, Izmir

2022-03-15

Active, closed

Abemaciclib (LY2835219) Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast Cancer

NCT05169567Breast Neoplasm, Neoplasm Metastasis

DrugsAbemaciclib·Fulvestrant

Eli Lilly and Company

Phase 3

368

Cordaleo, Meram, Adana, Ankara, Diyarbakır, Edirne, Istanbul, Malatya

2022-03-11

Active, closed

Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations

NCT05215340Metastatic Non Small Cell Lung Cancer

DrugsDato-DXd·Keytruda·Pembrolizumab

Daiichi Sankyo

Phase 3

740

Adana, Antalya, Bornova-İzmir, Çankaya, Istanbul, Seyhan /Adana

2022-03-04

Active, closed

Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis

NCT05201638Multiple Sclerosis, Relapsing-Remitting

DrugIMU-838

Immunic AG

Phase 3

1,100

Adana, Bursa, Istanbul, Kocaeli, Kütahya, Manisa, Sakarya, Samsun

2022-01-12

Recruiting

Post Marketing Clinical Follow Up Study to Evaluate Efficacy and Safety of the Occlutech PDA Occluder in Patients With Patent Ductus Arteriosus Defects

NCT05264753Patent Ductus Arteriosus

Occlutech International AB

Observational

255

Aydin, Eskişehir, Adana, Diyarbakır

2021-12-20

Active, closed

A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC)

NCT04819100Carcinoma, Non-Small-Cell Lung

DrugSelpercatinib

Eli Lilly and Company

Phase 3

152

Bornova, Izmir, Karsiyaka, Adana, Ankara, Antalya, Bursa, Diyarbakır, Edirne

2021-12-20

Active, closed

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT)

NCT04770753Non-Transfusion-dependent Alpha-Thalassemia, Non-Transfusion-dependent Beta-Thalassemia

DrugMitapivat

Agios Pharmaceuticals, Inc.

Phase 3

194

Adana, Antalya, Balcalı, Bornova, Fatih, Mersin

2021-12-20

Active, closed

Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma

NCT05097287Asthma

DrugDupilumab

Sanofi

Phase 4

1,339

Adana, Ankara, Istanbul, Izmir, Kayseri, Kirikkale, Mersin

2021-12-16

Active, closed

Pembrolizumab/Placebo Plus Paclitaxel With or Without Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer (MK-3475-B96/KEYNOTE-B96/ENGOT-ov65).

NCT05116189Ovarian Cancer, Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms

DrugsZirabev·Taxotere·Avastin·Keytruda

Merck Sharp & Dohme LLC

Phase 3

643

Sarçam, Fatih, Bornova, Adana, Ankara, Istanbul

2021-12-13

Active, closed

A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-TDT)

NCT04770779Transfusion-dependent Alpha-Thalassemia, Transfusion-dependent Beta-Thalassemia

DrugMitapivat

Agios Pharmaceuticals, Inc.

Phase 3

258

Adana, Antalya, Balcalı, Bornova, Fatih, Mersin

2021-11-30

Active, closed

Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease

NCT05030428Atherosclerotic Cardiovascular Disease

DrugInclisiran sodium

Novartis Pharmaceuticals

Phase 3

17,004

Izmir, Istanbul, Bursa, Konya, Ankara, Adana

2021-11-23

Active, closed

A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure

NCT04988295Carcinoma, Non-Small-Cell Lung

DrugsLazertinib·Amivantamab·Pemetrexed·Carboplatin

Janssen Research & Development, LLC

Phase 3

776

Adana, Ankara, Edirne, Istanbul, Izmir

2021-11-17

Recruiting

Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

NCT05145127Hemophilia A, Hemophilia B

DrugMarstacimab

Pfizer

Phase 3

245

Adana, Ankara, Gaziantep, Istanbul, Izmir, Kayseri, Samsun

2021-11-17

Active, closed

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer

NCT04940052Differentiated Thyroid Cancer (DTC)

DrugsDabrafenib·Trametinib

Novartis Pharmaceuticals

Phase 3

153

Istanbul, Edirne, Ankara, Adana

2021-11-15

Active, closed

Savolitinib Plus Durvalumab Versus Sunitinib and Durvalumab Monotherapy in MET-Driven, Unresectable and Locally Advanced or Metastatic PRCC

NCT05043090Papillary Renal Cell Carcinoma

DrugsSavolitinib·Sunitinib·Durvalumab

AstraZeneca

Phase 3

148

Adana, Ankara, Cordaleo, Edirne, Istanbul, Izmir, Kazımkarabekir

2021-10-28

Recruiting

ACCESS Registry: A Post Market Follow-up Study to Monitor the Safety, Performance and Usability of Occlutech Accessory Medical Devices

NCT05174442Heart Diseases

Occlutech International AB

Observational

685

Adana, Malatya, Izmir, Aydin, Istanbul, Antalya, Karaman, Diyarbakır

2021-10-14

Active, closed

A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors

NCT04931342Ovarian Cancer

DrugsCobimetinib·Ipatasertib·Giredestrant·Inavolisib

Hoffmann-La Roche

Phase 2

176

Adana, Ankara, Istanbul

2021-10-07

Active, closed

A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer

NCT04975308Breast Neoplasms, Neoplasm Metastasis

DrugsImlunestrant·Exemestane·Abemaciclib·Fulvestrant

Eli Lilly and Company

Phase 3

874

Stanbul, Üsküdar / Stanbul, Adana, Ankara, Antalya, Diyarbakır, Edirne, Istanbul

2021-10-04

Recruiting

A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments

NCT05020236Multiple Myeloma

DrugsDarzalex·Elranatamab·Pomalidomide·Daratumumab

Pfizer

Phase 3

893

Istanbul, Izmir, Adana, Ankara, Antalya, Gaziantep, Kayseri, Kocaeli

2021-10-04

Active, closed

A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease

NCT04929210Arthritis, Psoriatic

DrugsTremfya·Guselkumab

Janssen Research & Development, LLC

Phase 4

411

Adana, Ankara, Antalya, Bursa, Istanbul, Konya

2021-08-30

Recruiting

European Disease Registry on Retinopathy of Prematurity (ROP)

NCT04939571Retinopathy of Prematurity

University Medicine Greifswald

Observational

3,000

Adana, Ankara, Bursa, Istanbul, Ordu, Samsun

2021-08-06

Active, closed

Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab and Enfortumab Vedotin in Patients With Muscle Invasive Bladder Cancer Ineligible to Cisplatin or Who Refuse Cisplatin

NCT04960709Muscle Invasive Bladder Cancer

DrugsEnfortumab Vedotin·Tremelimumab·Durvalumab

AstraZeneca

Phase 3

712

Adana, Ankara, Antalya, Cordaleo, Edirne, Istanbul

2021-08-05

Active, closed

Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)

NCT04964934ER-Positive HER2-Negative Breast Cancer

DrugsCamizestrant·Anastrozole·Ribociclib·Abemaciclib

AstraZeneca

Phase 3

315

Adana, Ankara, Cordaleo, Izmir, Kadıkoy/Istanbul, Kayseri

2021-06-30

Active, closed

Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008).

NCT04895722Colorectal Cancer

DrugsPembrolizumab/Vibostolimab·MK-4830·Pembrolizumab/Favezelimab·Pembrolizumab/Quavonlimab

Merck Sharp & Dohme LLC

Phase 2

302

Adana, Ankara, Istanbul

2021-06-25

Active, closed

Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49)

NCT04895358Breast Neoplasms

DrugsLiposomal doxorubicin·Abraxane·Xeloda·Taxol

Merck Sharp & Dohme LLC

Phase 3

342

Bornova, Izmir, Karsiyaka, Adana, Ankara, Antalya, Istanbul, Malatya

2021-06-18

Recruiting

Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study

NCT04657822Sickle Cell Disease

DrugCrizanlizumab

Novartis Pharmaceuticals

Phase 4

130

Hatay, Adana

2021-06-10

Active, closed

D9319C00001- 1L OC Mono Global RCT

NCT04884360Ovarian Cancer

DrugOlaparib

AstraZeneca

Phase 3

366

Adana, Ankara, Cordaleo, Istanbul, Samsun

2021-05-31

Active, closed

Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04)

NCT04704934Gastric Cancer, Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma

DrugsRamucirumab·Trastuzumab deruxtecan·Paclitaxel

Daiichi Sankyo

Phase 3

490

Adana, Edirne, Istanbul, Malatya

2021-05-21

Active, closed

Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC

NCT04821622Prostate Cancer

DrugsTalazoparib·Enzalutamide

Pfizer

Phase 3

599

Adana, Ankara, Edirne, Istanbul, Malatya

2021-05-12

Active, closed

An Observational Study to Evaluate the Real-World Clinical Management and Outcomes of ALK-Positive Advanced NSCLC Participants Treated With Alectinib

NCT04764188NSCLC

DrugAlectinib

Hoffmann-La Roche

Observational

800

Adana, Ankara, Antalya, Denizli, Edirne, Istanbul, Izmir, Malatya

2021-05-10

Active, closed

A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy

NCT04873362Breast Cancer

DrugsTrastuzumab emtansine·Herceptin·Tecentriq·Trastuzumab

Hoffmann-La Roche

Phase 3

1,188

Adana, Ankara, Antalya, Bornova, ?zm?r, Diyarbakır, Edirne, Istanbul, Izmir

2021-05-04

Active, closed

Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)

NCT04784715Breast Cancer; HER2-positive; Metastatic

DrugsPertuzumab·Trastuzumab deruxtecan·Trastuzumab

AstraZeneca

Phase 3

1,157

Adana, Ankara, Cordaleo, Malatya, Samsun

2021-04-26

Active, closed

Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)

NCT04822181Non-alcoholic Steatohepatitis

DrugSemaglutide

Novo Nordisk A/S

Phase 3

1,205

Adana, Ankara, Bursa, Istanbul, Izmir, Kocaeli, Mersin, Yüreğir/Adana

2021-04-01

Recruiting

Rectosigmoid Resection vs Seromuscular Tumor Shaving in Ovarian Cancer Surgery

NCT04665635Epithelial Ovarian Cancer, Rectosigmoid Cancer Metastatic

Cukurova University

Not applicable

120

Adana

2021-03-01

Active, closed

Extension Study to Evaluate the Long-Term Outcomes of Pediatric Patients Who Received Treatment for Retinopathy of Prematurity in the VGFTe-ROP-1920 Study (Acronym: Butterfleye Next)

NCT04515524Retinopathy of Prematurity

Regeneron Pharmaceuticals

Observational

100

Adana, Ankara, Eskişehir

2021-02-05

Active, closed

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors

NCT04431726Severe Hemophilia A

DrugEmicizumab

Hoffmann-La Roche

Phase 3

Adana, Ankara, Izmir, Samsun

2021-02-04

Active, closed

Phase 1b Study of Dato-DXd in Combination With Immunotherapy With or Without Carboplatin in Advanced or Metastatic Non-Small Cell Lung Cancer

NCT04612751Advanced or Metastatic NSCLC

DrugsSabestomig·Volrustomig·Rilvegostomig·Dato-DXd

AstraZeneca

Phase 1

155

Adana, Ankara, Istanbul, Izmir

2021-02-02

Active, closed

A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)

NCT04624659Sickle Cell Disease

DrugEtavopivat

Forma Therapeutics, Inc.

Phase 3

450

Adana, Ankara, Izmir, Mersin

2021-01-29

Active, closed

A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease

NCT04711252ER-Positive HER2-Negative Breast Cancer

DrugsCamizestrant·Anastrozole·Palbociclib

AstraZeneca

Phase 3

1,371

Adana, Ankara, Izmir, Kayseri

2021-01-28

Active, closed

Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)

NCT04634877Endometrial Neoplasms

DrugsKeytruda·Docetaxel·Paclitaxel·Cisplatin

Merck Sharp & Dohme LLC

Phase 3

990

Adana, Ankara, Istanbul, Izmir

2021-01-10

Active, closed

Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-small Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy

NCT04655976Lung Cancer, Non-Small Cell

DrugsCobolimab·Dostarlimab·Docetaxel

GlaxoSmithKline

Phase 2/3

758

Adana, Antalya, Izmir

2020-12-08

Active, closed

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

NCT04658862Urinary Bladder Neoplasms

DrugsTAR-200·Cetrelimab·Gemcitabine·Cisplatin

Janssen Research & Development, LLC

Phase 3

518

Adana, Ankara, Balçova, Fatih, Gaziantep, Istanbul, Izmir, Malatya

2020-12-07

Active, closed

Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer

NCT04592913Gastrointestinal Neoplasms, Esophagogastric Junction

DrugDurvalumab

AstraZeneca

Phase 3

957

Adana, Ankara, Erzurum, Istanbul, Samsun

2020-11-17

Active, closed

A Study of Adding Apalutamide to Radiotherapy and LHRH Agonist in High-Risk Patients With Hormone-Sensitive Prostate Cancer

NCT04557059Prostatic Neoplasms

DrugsLhrha·Apalutamide

Janssen Pharmaceutica N.V., Belgium

Phase 3

691

Adana, Ankara, Istanbul, Izmir, Sakarya

2020-11-12

Active, closed

RADIANT: A Study of Radium-223 Dichloride (Xofigo) vs Enzalutamide or Abiraterone (ARPIs, Androgen Receptor Pathway Inhibitors) in Patients With Prostate Cancer That Has Spread to the Bones (mCRPC, Metastatic Castration-Resistant Prostate Cancer)

NCT04597125Metastatic Castrate Resistant Prostate Cancer (mCRPC)

Bayer

Phase 4

654

Adana, Ankara, Edirne, Gaziantep, Istanbul, Izmir, Kayseri, Mersin

2020-11-09

Active, closed

A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions

NCT04538664Carcinoma, Non-Small-Cell Lung

DrugsAmivantamab·Pemetrexed·Carboplatin

Janssen Research & Development, LLC

Phase 3

308

Adana, Ankara, Edirne, Istanbul, Izmir

2020-10-13

Active, closed

A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

NCT04487080Carcinoma, Non-Small-Cell Lung

DrugsLazertinib·Amivantamab·Osimertinib

Janssen Research & Development, LLC

Phase 3

1,074

Adana, Ankara, Edirne, Istanbul, Izmir, Konya

2020-09-30

Active, closed

A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-MutatedProstatic Neoplasms (mCSPC)

NCT04497844Prostatic Neoplasms

DrugsAbiraterone acetate·Prednisone

Janssen Research & Development, LLC

Phase 3

696

Adana, Ankara, Bursa, Edirne, Istanbul, Izmir, Sakarya, Samsun

2020-09-23

Active, closed

Study to Evaluate the Efficacy and Safety of PF-07055480 / Giroctocogene Fitelparvovec Gene Therapy in Moderately Severe to Severe Hemophilia A Adults

NCT04370054Hemophilia A

Pfizer

Phase 3

Adana, Gaziantep, Izmir

2020-08-18

Recruiting

AutoInflammatory Disease Alliance Registry (AIDA)

NCT05200715Hereditary Autoinflammatory Diseases, Schnitzler Syndrome, Behcet Syndrome, PFAPA Syndrome

University of Siena

Observational

3,500

Adana, Ankara, Istanbul, Izmir, Manisa, Sakarya, Sivas

2020-08-06

Active, closed

Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

NCT04273945Pulmonary Arterial Hypertension

DrugMacitentan

Actelion

Phase 3

935

Adana, Ankara, Antalya, Bursa, Denizli, Istanbul, Izmir, Kartal Istanbul

2020-06-30

Active, closed

A Study of Selpercatinib (LY3527723) in Participants With Advanced or Metastatic RET Fusion-Positive Non-Small Cell Lung Cancer

NCT04194944Non-Small Cell Lung Cancer

DrugsSelpercatinib·Pemetrexed·Cisplatin·Carboplatin

Eli Lilly and Company

Phase 3

261

Bornova, Adana, Ankara, Antalya, Diyarbakır, Edirne, Istanbul, Izmir

2020-02-17

Active, closed

A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Participants With PIK3CA-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer

NCT04191499Breast Cancer

DrugsInavolisib·Palbociclib·Fulvestrant

Hoffmann-La Roche

Phase 2/3

325

Adana, Ankara, Bornova, ?zm?r, Istanbul

2020-01-29

Active, closed

A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension

NCT04175600Hypertension, Pulmonary

DrugSelexipag

Actelion

Phase 3

138

Adana, Ankara, Istanbul, Izmir

2020-01-16

Active, closed

A Trial to Compare the Efficacy, Safety, Pharmacokinetics and Immunogenicity of HD204 to Avastin® in Advanced Non-squamous Non-small Cell Lung Cancer Patients

NCT03390686Lung Cancer, Non-small Cell Lung Cancer

DrugsHD204·Avastin·Taxol·Paclitaxel

Prestige Biopharma Limited

Phase 3

650

Adana

2019-11-15

Active, closed

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors

NCT04082429Haemophilia A Without Inhibitors, Haemophilia B Without Inhibitors

DrugConcizumab

Novo Nordisk A/S

Phase 3

156

Ankara, Capa-ISTANBUL, Adana, Edirne, Izmir, Samsun

2019-11-13

Active, closed

Dose Escalation Study of a PD1-LAG3 Bispecific Antibody in Patients With Advanced and/or Metastatic Solid Tumors

NCT04140500Solid Tumors, Metastatic Melanoma, Non-small Cell Lung Cancer, Esophageal Squamous Cell Carcinoma

DrugTobemstomig

Hoffmann-La Roche

Phase 1/2

170

Adana, Ankara, Sihhiye/Ankara, Yen?mahalle

2019-11-11

Active, closed

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitors

NCT04083781Haemophilia A With Inhibitors, Haemophilia B With Inhibitors

DrugConcizumab

Novo Nordisk A/S

Phase 3

134

Capa-ISTANBUL, Antalya, Adana

2019-10-21

By invitation

A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

NCT03683186PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension

United Therapeutics

Phase 3

1,000

Eskişehir, Adana, Mersin, Ankara, Bursa, Istanbul, Izmir

2019-09-23

Recruiting

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

NCT04064060Myelodysplastic Syndromes (MDS), Beta-thalassemia, Myeloproliferative Neoplasm(MPN)-Associated Myelofibrosis

DrugLuspatercept

Celgene

Phase 3

665

Adana, Ankara, Istanbul, Izmir, Mersin

2019-08-12

Active, closed

A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)

NCT04008030Metastatic Colorectal Cancer

DrugsFluorouracil·Leucovorin·Ipilimumab·Irinotecan

Bristol-Myers Squibb

Phase 3

839

Adana, Istanbul

2019-08-05

Active, closed

A Study to Evaluate the Efficacy and Safety of Factor IX Gene Therapy With PF-06838435 in Adult Males With Moderately Severe to Severe Hemophilia B

NCT03861273Hemophilia B

Pfizer

Phase 3

Adana, Gaziantep, Istanbul, Izmir

2019-07-29

Active, closed

Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients

NCT03814746Sickle Cell Disease (SCD)

DrugCrizanlizumab

Novartis Pharmaceuticals

Phase 3

253

Adana

2019-07-26

Active, closed

Avelumab Program Rollover Study

NCT03815643Solid Tumors

DrugAvelumab

EMD Serono Research & Development Institute, Inc.

Phase 3

205

Adana, Ankara, Istanbul, Izmir, Mersin

2019-03-22

Active, closed

A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML

NCT03591510FLT3-mutated Acute Myeloid Leukemia

DrugsMidostaurin·Mitoxantrone·Idarubicin·Daunorubicin

Novartis Pharmaceuticals

Phase 2

Adana

2019-03-13

Active, closed

A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate Cancer

NCT03748641Castration-Resistant Prostatic Cancer

DrugsAbiraterone acetate·Niraparib·Prednisone

Janssen Research & Development, LLC

Phase 3

765

Adana, Ankara, Antalya, Edirne, Istanbul, Izmir, Kocaeli

2019-01-25

Active, closed

Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients

NCT03737643Advanced Ovarian Cancer

DrugsOlaparib·Durvalumab·Paclitaxel·Bevacizumab

AstraZeneca

Phase 3

1,407

Adana, Ankara, Istanbul, Izmir

2019-01-04

Active, closed

Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated, Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer (MK-7339-002 / LYNK-002)

NCT03742895Advanced Solid Neoplasms

DrugOlaparib

Merck Sharp & Dohme LLC

Phase 2

329

Konya, Adana, Ankara, Antalya, Edirne, Istanbul, Izmir

2018-12-12

Active, closed

A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients

NCT03706690Carcinoma, Non-Small-Cell Lung

DrugDurvalumab

AstraZeneca

Phase 3

407

Adana, Ankara, Edirne, Istanbul, Konya, Malatya

2018-11-27

Active, closed

Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer

NCT03732820Metastatic Castration-resistant Prostate Cancer

DrugsZytiga·Abiraterone acetate·Olaparib

AstraZeneca

Phase 3

895

Adana, Ankara, Cordaleo, Istanbul, Izmir

2018-10-31

Active, closed

Study of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung Cancer

NCT03539536Non-small Cell Lung Cancer

DrugTelisotuzumab vedotin

AbbVie

Phase 2

270

Adana, Ankara, Antalya, Edirne, Istanbul, Istanbul, Izmir

2018-10-10

Active, closed

Study of Durvalumab + Tremelimumab, Durvalumab, and Placebo in Limited Stage Small-Cell Lung Cancer in Patients Who Have Not Progressed Following Concurrent Chemoradiation Therapy

NCT03703297Small Cell Lung Cancer

DrugsTremelimumab·Durvalumab

AstraZeneca

Phase 3

730

Adana, Ankara, Antalya, Edirne, Istanbul, Izmir, Konya, Samsun

2018-09-27

Active, closed

Study of Durvalumab Given With Chemotherapy, Durvalumab in Combination With Tremelimumab Given With Chemotherapy, or Chemotherapy in Patients With Unresectable Urothelial Cancer

NCT03682068Unresectable Locally Advanced Urothelial Cancer, Metastatic Urothelial Cancer

DrugsTremelimumab·Durvalumab·Gemcitabine·Cisplatin

AstraZeneca

Phase 3

1,246

Adana, Adapazarı, Ankara, Edirne, Istanbul, Izmir

2018-09-27

Recruiting

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

NCT03486873Solid Tumors, Hematologic Malignancies

DrugsPembrolizumab/Favezelimab·) Berahyaluronidase alfa·Olaparib·Lenvatinib

Merck Sharp & Dohme LLC

Phase 3

3,500

Üsküdar /Istanbul, Balçova, Adana, Ankara, Antalya, Edirne, Erzurum, Istanbul

2018-08-21

Active, closed

A Study Comparing Adjuvant Alectinib Versus Adjuvant Platinum-Based Chemotherapy in Patients With ALK Positive Non-Small Cell Lung Cancer

NCT03456076Carcinoma, Non-Small-Cell Lung

DrugsAlectinib·Vinorelbine·Pemetrexed·Gemcitabine

Hoffmann-La Roche

Phase 3

257

Adana, Ankara, Istanbul, Izmir, Malatya, Samsun

2018-08-16

Active, closed

A Global Study to Assess the Effects of Osimertinib Following Chemoradiation in Patients With Stage III Unresectable Non-small Cell Lung Cancer (LAURA)

NCT03521154Non Small Cell Lung Cancer (Stage III)

DrugOsimertinib

AstraZeneca

Phase 3

216

Adana, Adapazarı, Ankara, Istanbul, Izmir

2018-07-19

Active, closed

A Study of Erdafitinib in Participants With Metastatic or Locally Advanced Urothelial Cancer

NCT03473743Urothelial Carcinoma

DrugsErdafitinib·Cetrelimab·Cisplatin·Carboplatin

Janssen Research & Development, LLC

Phase 1/2

125

Adana, Ankara, Aydin, Edirne, Istanbul, Izmir, Kocaeli, Konya

2018-04-05

Active, closed

A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

NCT03390504Urothelial Cancer

DrugsVinflunine·Erdafitinib·Docetaxel·Pembrolizumab

Janssen Research & Development, LLC

Phase 3

629

Adana, Ankara, Istanbul, Izmir, Kocaeli, Malatya

2018-03-23

Active, closed

A Study to Investigate the Clinical Benefit of Isatuximab in Combination With Bortezomib, Lenalidomide and Dexamethasone in Adults With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

NCT03319667Plasma Cell Myeloma

DrugsVelcade·Isatuximab·Bortezomib·Lenalidomide

Sanofi

Phase 3

475

Adana, Ankara, Istanbul, Izmir, Kayseri, Samsun

2017-12-07

Active, closed

A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)

NCT03178552Non-Small Cell Lung Cancer

DrugsCobimetinib·Divarasib·Vemurafenib·Entrectinib

Hoffmann-La Roche

Phase 2/3

1,000

Adana, Antalya, Edirne, Istanbul, Kar??yaka, Sihhiye/Ankara

2017-09-22

Active, closed

Endocrine Therapy With or Without Abemaciclib (LY2835219) Following Surgery in Participants With Breast Cancer

NCT03155997Breast Cancer

DrugAbemaciclib

Eli Lilly and Company

Phase 3

5,637

Istanbul- Fatih, Üsküdar/stanbul, Bornova, Izmir, Karsiyaka, Ankara, Adana, Antalya, Edirne

2017-07-12

Active, closed

A Study Of Lorlatinib Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC

NCT03052608Carcinoma, Non-Small-Cell Lung

DrugsLorlatinib·Crizotinib

Pfizer

Phase 3

296

Adana, Istanbul, Izmir

2017-04-27

Active, closed

A Study of Ramucirumab (LY3009806) or Merestinib (LY2801653) in Advanced or Metastatic Biliary Tract Cancer

NCT02711553Biliary Tract Cancer, Metastatic Cancer, Advanced Cancer

DrugsRamucirumab·Gemcitabine·Cisplatin

Eli Lilly and Company

Phase 2

309

Adana, Ankara, Antalya, Edirne, Istanbul

2016-05-19

Active, closed

Study to Evaluate Imetelstat (GRN163L) in Participants With International Prognostic Scoring System (IPSS) Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)

NCT02598661Myelodysplastic Syndromes

DrugImetelstat Sodium

Geron Corporation

Phase 2/3

289

Ankara, Izmir, Adana

2016-01-12

Active, closed

An Efficacy and Safety Study of JNJ-56021927 (Apalutamide) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS

NCT02531516Prostatic Neoplasms

DrugsGnRH·Bicalutamide·Apalutamide

Aragon Pharmaceuticals, Inc.

Phase 3

1,503

Adana, Ankara, Edirne, Istanbul, Izmir, Kayseri, Kocaeli

2015-11-19

Active, closed

Study of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE)

NCT02542293Non Small Cell Lung Carcinoma NSCLC

DrugsTremelimumab·Durvalumab·Pemetrexed·Gemcitabine

AstraZeneca

Phase 3

953

Adana, Ankara, Istanbul, Izmir

2015-11-03

Active, closed

A Study of Ramucirumab (LY3009806) in Combination With Erlotinib in Previously Untreated Participants With EGFR Mutation-Positive Metastatic NSCLC (RELAY)

NCT02411448Metastatic Non-Small Cell Lung Cancer

DrugsGefitinib·Erlotinib·Ramucirumab·Osimertinib

Eli Lilly and Company

Phase 3

545

Bornova, Adana, Edirne, Malatya

2015-05-06

Recruiting

International (Pediatric) Peritoneal Biobank

NCT01893710Kidney Failure, Chronic, Peritoneal Dialysis Complication, Transplantation, Healthy

Heidelberg University

Observational

500

Adana, Istanbul

2011-02-01

Recruiting

International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

NCT00358943Gaucher Disease, Cerebroside Lipidosis Syndrome, Glucocerebrosidase Deficiency Disease, Glucosylceramide Beta-Glucosidase Deficiency Disease

Genzyme, a Sanofi Company

Observational

12,000

Adana, Ankara, Istanbul, Izmir, Malatya

1991-04-01

Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Turkish investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 14 November 2026. https://priyalifescience.com/clinical-trials-turkey/city/adana

Query this register directly

GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Turkey and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,436 studies in total at the last sync on 13 Nov 2026, 03:18 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 380 of those studies with a site in Adana.

How many clinical trials are recruiting in Adana?

184 of the 380 studies on this page are recruiting new participants as of the 13 Nov 2026, 03:18 UTC sync. A further 22 have not yet opened recruitment, 165 are active but closed to new participants, and 9 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Adana), 380 studies
Phase	Studies	Recruiting	Share
Phase 3	220	101	57.9%
Not applicable	45	22	11.8%
Phase 2	43	21	11.3%
Observational	26	19	6.8%
Phase 1/2	15	10	3.9%
Phase 2/3	15	6	3.9%
Phase 1	9	4	2.4%
Phase 4	6	1	1.6%
Early Phase 1	1	0	0.3%

Most active sponsors

Lead sponsors with the most studies (Adana)
Lead sponsor	Studies	Recruiting
Merck Sharp & Dohme LLC	44	28
AstraZeneca	37	15
Cukurova University	28	14
Eli Lilly and Company	21	9
Hoffmann-La Roche	16	5
Janssen Research & Development, LLC	16	4
Novo Nordisk A/S	15	5
Amgen	13	6
Pfizer	13	6
Novartis Pharmaceuticals	12	5

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.