Paracetamol clinical trials
Paracetamol is named as an intervention in 22 current clinical trials in our Turkey, Egypt, Brazil, Denmark, Poland, UK, Germany, Spain, Czechia, USA, India, France, Italy, Belgium, Austria, Norway, Singapore and Israel registers. 8 are recruiting patients now. The most common phase is Phase 4. The sponsor with the most trials is Sanofi Pasteur, a Sanofi Company (1). The most-studied condition is Obesity. The EU clinical trials register (CTIS) separately lists 9 authorised or ongoing trials.
What health systems spend on Paracetamol
All medicines →From NHSBSA Prescription Cost Analysis (Open Government Licence v3.0) and CMS State Drug Utilization Data. Both are gross amounts: neither system publishes its discounts or rebates per drug. Products combining several substances are not counted here.
Patient leaflets for Paracetamol
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- IEIreland: 68 products on the HPRA listEach product record links to the HPRA, which publishes the leaflet and SmPC.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Trials by status
Trials by phase
Clinical trials of Paracetamol
22 trialsRegisters list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Paracetamol in the EU trials register (CTIS)
9 trialsAuthorised or ongoing trials in the EU Clinical Trials Information System that list a product containing Paracetamol. Many trials are registered in both CTIS and ClinicalTrials.gov, so these are shown separately rather than added to the count above. Trials with a site in Ireland are listed first.
Paracetamol across our data
Ireland · EU · USThe same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.
Licensed in Ireland (HPRA)
68 single-substance products containing Paracetamol on the HPRA medicines list.
- Calpol 120 mg/ 5 ml Sugar Free Infant Oral SuspensionJNTL Consumer Health (Ireland) Limited · PA23490/003/004 · Marketed
- Calpol 120 mg/5 ml Infant Oral SuspensionJNTL Consumer Health (Ireland) Limited · PA23490/003/001 · Marketed
- Calpol Six Plus 250 mg/5 ml Sugar/Colour Free Oral SuspensionJNTL Consumer Health I (Ireland) Limited · PA23490/003/003 · Marketed
- Calpol Six Plus Fastmelts 250 mg Paracetamol orodispersible tabletsJNTL Consumer Health I (Ireland) Limited · PA23490/003/005 · Marketed
- Junior Parapaed Paracetamol Oral Suspension 120 mg/5 mlPinewood Laboratories Limited · PA0281/002/001 · Marketed
Supply shortages
- Azur compositumGermany (BfArM) · Other reason · 16 Aug 2023 to 30 Dec 2026
Conditions studied with Paracetamol
46 conditionsAll 46 conditions
| Condition (as registered) | Trials |
|---|---|
| Obesity | 2 |
| Overweight | 2 |
| Paracetamol | 2 |
| Meningococcal Immunization | 1 |
| Healthy Volunteers | 1 |
| Overweight and/or Obesity | 1 |
| Drug Interaction | 1 |
| Knee Osteoarthritis (Knee OA) | 1 |
| Lumbar Radiculopathy | 1 |
| Lumbar Disc Herniation | 1 |
| Lumbar Disc Disease | 1 |
| Breast Cancer | 1 |
| Cefazolin | 1 |
| Relapsing Remitting Multiple Sclerosis | 1 |
| Secondary Progressive Multiple Sclerosis | 1 |
| Primary Progressive Multiple Sclerosis | 1 |
| Pancreatitis, Acute | 1 |
| Pain, Acute | 1 |
| Pancreatic Disease | 1 |
| Pancreatic Diseases | 1 |
| Obesity, Morbid | 1 |
| Urolithiasis | 1 |
| Kidney Stones | 1 |
| Ureteral Stones | 1 |
| Posterior Spinal Instrumentation Patients | 1 |
| Lung Cancer (NSCLC) | 1 |
| Lung Adenocarcinoma | 1 |
| Video Assisted Thoracic Surgery (VATS) | 1 |
| Propofol Injection Pain | 1 |
| Rocuronium Injection Pain | 1 |
| Osteoarthritis, Knee | 1 |
| Hematologic Test | 1 |
| Agranulocytosis | 1 |
| Side Effects | 1 |
| Blood Pressure Monitoring | 1 |
| Pain | 1 |
| Pain Management | 1 |
| Birth | 1 |
| Hypotension Drug-Induced | 1 |
| Emergency Surgery | 1 |
| Migraine | 1 |
| Migraine Disease | 1 |
| Migraine Headache | 1 |
| Migraine Headache, With or Without Aura | 1 |
| Percutaneous Nephrolithotripsy (PCNL) | 1 |
| Postoperative Pain | 1 |
Sponsors
lead sponsor per trial+ 7 more sponsors in the trial list above.
By country register
A trial with sites in more than one country appears in each of those registers. CTIS does not publish a recruiting flag; its trials may also appear in the registers above.
Related compounds
Questions about Paracetamol trials
How many clinical trials are testing Paracetamol?
22 current trials in our Turkey, Egypt, Brazil, Denmark, Poland, UK, Germany, Spain, Czechia, USA, India, France, Italy, Belgium, Austria, Norway, Singapore and Israel registers name Paracetamol as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.
Are Paracetamol trials recruiting patients?
Yes. 8 of the 22 trials are recruiting: 3 with sites in Egypt, 1 with sites in Brazil, 1 with sites in Poland, 1 with sites in Belgium, 1 with sites in Norway and 1 with sites in Israel. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Paracetamol clinical trials?
Sanofi Pasteur, a Sanofi Company (1), Pfizer (1), All India Institute of Medical Sciences, Jodhpur (1) and St Joseph University, Beirut, Lebanon (1), among 22 lead sponsors in total. The number in brackets is how many trials each organisation leads.
Is Paracetamol licensed in Ireland?
Yes. The HPRA medicines list includes 68 single-substance products containing Paracetamol, for example Calpol 120 mg/ 5 ml Sugar Free Infant Oral Suspension (JNTL Consumer Health (Ireland) Limited). A licence does not mean a product is currently marketed or reimbursed; see each product's record.
Is there a Paracetamol shortage?
The registers we track list 1 entry for Paracetamol: 1 German notice. Shortages are product- and country-specific; check with a pharmacist.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Paracetamol works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Paracetamol works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Paracetamol (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.