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Novo Nordisk clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine and the EU Clinical Trials Information System (CTIS) — current trials in our USA, UK, India, China, Ireland and EU (CTIS) registers with Novo Nordisk as lead sponsor. Synced 26 Sep 2026
94Current trials
36Recruiting now
20Drugs in these trials
6Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

Novo Nordisk is the lead sponsor of 94 current clinical trials in our USA, UK, India, China, Ireland and EU (CTIS) registers. 36 are recruiting patients now. The most common phase is Phase 3. The drugs named most often in its trials are Semaglutide, Cagrilintide and NNC0487-0111. The most-studied condition is Obesity.

Company profile on this site (news, sites, medicines, approvals): Novo Nordisk A/S (DK) →

ClinicalTrials.gov trials by status

  • Recruiting3643%
  • Not yet open78%
  • Active, closed2733%
  • By invitation1316%

Trials by phase

  • Phase 34251%
  • Phase 11518%
  • Observational1417%
  • Phase 21012%
  • Phase 422%
01

Clinical trials sponsored by Novo Nordisk

83 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
NCT07509307 · Obesity, Overweight, Osteoarthritis, Knee
Phase 3 Recruiting 2026-04 USA
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
NCT07207811 · ClinicalTrials.gov ↗ · Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Phase 3 Recruiting 2025-10 Ireland, UK, USA, China
AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
NCT07571005 · ClinicalTrials.gov ↗ · Obesity, Overweight, Obstructive Sleep Apnoea
Phase 3 Recruiting 2026-05 USA, India, China
AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
NCT07571109 · ClinicalTrials.gov ↗ · Obesity, Overweight, Obstructive Sleep Apnoea
Phase 3 Recruiting 2026-05 USA, India, China
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
NCT07567001 · ClinicalTrials.gov ↗ · Obesity, Heart Failure
Phase 3 Recruiting 2026-05 UK, USA, India, China
A Study Looking at How Weekly Injections of Two Hormones - GIP and Amylin - Affect Stomach-related Side Effects in People Who Are Overweight or Obese
NCT07411560 · Overweight, Obese
Phase 1 Recruiting 2026-02 UK
A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy
NCT06979375 · ClinicalTrials.gov ↗ · Heart Failure
Drug: CDR132L
Phase 2 Recruiting 2025-06 UK, India
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
NCT06609226 · ClinicalTrials.gov ↗ · Sickle Cell Disease, Thalassemia
Phase 3 Recruiting 2025-01 UK, USA, India
A Research Study on the Effects of NNC0537-1482 in Participants With Heart Failure
NCT07218627 · Heart Failure
Phase 1 Recruiting 2025-10 UK
A Research Study to See How Safe is Eptacog Alfa When Used to Stop Heavy Bleeding in Women After Giving Birth in India
NCT07157423 · ClinicalTrials.gov ↗ · Severe Postpartum Haemorrhage
Phase 4 Recruiting 2025-08 India
A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity
NCT07767175 · Overweight, Obesity
Phase 1 Recruiting 2026-08 USA
A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
NCT06612268 · ClinicalTrials.gov ↗ · Sickle Cell Disease
Phase 3 Recruiting 2025-02 UK, USA, India
A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
NCT06717698 · ClinicalTrials.gov ↗ · Chronic Kidney Disease
Phase 2 Recruiting 2024-12 USA, India
Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight
NCT07770841 · Overweight, Obesity
Phase 3 Recruiting 2026-08 USA
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
NCT06979362 · ClinicalTrials.gov ↗ · Heart Failure
Drug: CDR132L
Phase 2 Recruiting 2025-06 UK, USA, India
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
NCT07253285 · ClinicalTrials.gov ↗ · Overweight, Obesity
Phase 3 Recruiting 2026-01 UK, USA, India, China
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
NCT07797335 · ClinicalTrials.gov ↗ · Type 2 Diabetes, Cardiovascular Risk
Phase 3 Recruiting 2026-08 UK, USA, India, China
A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A
NCT07220564 · ClinicalTrials.gov ↗ · Haemophilia A
Phase 1 Recruiting 2025-10 UK, USA
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes
NCT07282613 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Type 2
Drug: CagriSema
Phase 3 Recruiting 2026-08 USA, India
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
NCT07668388 · Diabetes Mellitus, Type 2
Phase 2 Recruiting 2026-06 USA
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
NCT07339423 · ClinicalTrials.gov ↗ · Obesity
Phase 3 Recruiting 2026-02 UK, USA
Multiple Dose Study for a New Medication to Potentially Treat Liver Diseases
NCT06891365 · ClinicalTrials.gov ↗ · Healthy Volunteers, Hepatic Steatosis
Phase 1 Recruiting 2025-03 UK
Management Concepts of Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) Among Chinese Physicians
NCT07682363 · ClinicalTrials.gov ↗ · Liver Disease
Observational Recruiting 2026-06 China
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes
NCT07415954 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Type 2
Phase 2 Recruiting 2026-04 USA
A Research Study Looking Into How NNC0662-0419 Works With Birth Control Pills and Emptying of the Stomach in Women Not Able to Become Pregnant With Excess Body Weight
NCT07525791 · ClinicalTrials.gov ↗ · Overweight, Obesity
Phase 1 Recruiting 2026-04 USA
A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity
NCT07395687 · ClinicalTrials.gov ↗ · Overweight, Obesity
Drug: UBT251
Phase 2 Recruiting 2026-02 USA
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
NCT07564414 · ClinicalTrials.gov ↗ · Obesity, Type 2 Diabetes
Phase 3 Recruiting 2026-05 USA
A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body Weight
NCT07710768 · ClinicalTrials.gov ↗ · Obesity, Overweight
Drug: UBT251
Phase 1 Recruiting 2026-07 USA
A Study to See How Safe a New Medicine (NNC6989-0001) is in Healthy People Living With Overweight or Obesity
NCT07437079 · ClinicalTrials.gov ↗ · Overweight, Obesity
Phase 1 Recruiting 2026-02 USA
A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity
NCT07566390 · ClinicalTrials.gov ↗ · Obesity, Overweight
Phase 1 Recruiting 2026-05 USA
AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
NCT07533175 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Overweight, Obesity
Phase 3 Recruiting 2026-04 USA
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
NCT07481630 · ClinicalTrials.gov ↗ · Obesity, Knee Osteoarthritis (OA)
Phase 3 Recruiting 2026-04 USA
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
NCT07607587 · ClinicalTrials.gov ↗ · Obesity, Overweight
Phase 1 Recruiting 2026-05 USA
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
NCT07745504 · ClinicalTrials.gov ↗ · Overweight, Obesity
Phase 3 Recruiting 2026-08 USA
Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)
NCT07225816 · ClinicalTrials.gov ↗ · Obesity
Phase 1 Recruiting 2025-11 USA
A Research Study to Evaluate the Safety of NNC4004-0002 When Given to Participants With Asymptomatic Hyperuricemia
NCT06859073 · ClinicalTrials.gov ↗ · Healthy Volunteers, Hyperuricemia
Phase 1 Recruiting 2024-11 USA
AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
NCT07400107 · Obesity, Overweight, Diabetes Mellitus, Type 2
Phase 3 Not yet open 2026-05 USA, India
A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A
NCT07830732 · ClinicalTrials.gov ↗ · Haemophilia A
Phase 3 Not yet open 2026-10 UK, USA, India
AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose Weight
NCT07668401 · ClinicalTrials.gov ↗ · Obesity, Overweight
Phase 3 Not yet open 2027-01 India
Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema
NCT07817251 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Type 2
Drug: CagriSema
Phase 3 Not yet open 2026-09 USA
A Study to See How Safe a New Medicine (NNC0642-1895) is in Healthy People
NCT07829406 · ClinicalTrials.gov ↗ · Healthy Volunteers
Phase 1 Not yet open 2026-09 USA
AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight
NCT07720271 · ClinicalTrials.gov ↗ · Overweight, Obesity
Phase 3 Not yet open 2026-09 USA
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide
NCT07668414 · ClinicalTrials.gov ↗ · Overweight, Obesity
Phase 3 Not yet open 2026-09 USA
Defeat Rare Disease in Asia and Pacific (APAC) DRDA - Haemophilia
NCT07163260 · Haemophilia
Observational By invitation 2025-01 India
A Study to Follow Paediatric Participants With Growth Hormone Deficiency Treated With Somapacitan for Long Term Safety Information and Clinical Parameters
NCT06709040 · Growth Hormone Deficiency, Neoplasms, Diabetes Mellitus Type 2
Observational By invitation 2024-12 UK
A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Information
NCT05718570 · Adult Growth Hormone Deficiency
Observational By invitation 2023-02 USA
An Observational Study of Patients With Moderate Parkinson's Disease
NCT05779475 · Parkinson Disease
Observational By invitation 2023-04 UK, USA
A Two-year Prospective, Observational Study of Wegovy in Real-world Clinical Practice
NCT07055607 · ClinicalTrials.gov ↗ · Obesity
Observational By invitation 2025-05 UK
A Study to Evaluate Safety of Exposure to Wegovy During Pregnancy
NCT05872022 · ClinicalTrials.gov ↗ · Pregnancy, Obesity, Overweight
Observational By invitation 2023-07 UK, USA
A Study Following Males With Haemophilia B on Prophylaxis With Refixia/REBINYN
NCT03745924 · ClinicalTrials.gov ↗ · Haemophilia B
Observational By invitation 2019-04 UK
Adverse Event Data Collection From External Registries on Nonacog Beta Pegol
NCT03690336 · ClinicalTrials.gov ↗ · Haemophilia B
Observational By invitation 2018-10 UK
Database Linkage Study to Evaluate the Risk of Medullary Thyroid Carcinoma
NCT07713901 · ClinicalTrials.gov ↗ · Medullary Thyroid Carcinoma
Observational By invitation 2025-12 USA
An Active Surveillance Program for Cases of Medullary Thyroid Carcinoma (MTC)
NCT01511393 · ClinicalTrials.gov ↗ · Diabetes, Diabetes Mellitus, Type 2, Medullary Thyroid Carcinoma
Observational By invitation 2012-01 USA
A Study to Evaluate the Safety of Exposure to Wegovy During Pregnancy
NCT05503927 · ClinicalTrials.gov ↗ · Pregnancy, Obesity, Overweight
Observational By invitation 2020-02 USA
Research Study to Examine Blood Sugar Control, Treatment Satisfaction and Adherence in People With Type 2 Diabetes After Switching From Daily Basal Insulin to Once-weekly Insulin Icodec
NCT07658417 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Type 2
Observational By invitation 2026-07 China
A Two-armed Real-world Study of Ozempic (OW Semaglutide) to Evaluate Its Adherence and Persistence Compared With Other Anti-diabetic Drugs Among Adult T2DM Patients in China
NCT07456774 · ClinicalTrials.gov ↗ · Type 2 Diabetes
Observational By invitation 2026-02 China
A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors
NCT05135559 · Haemophilia A and B With and Without Inhibitors
Phase 3 Active, closed 2022-03 UK, USA, India
ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack
NCT06118281 · Cardiovascular Risk, Acute Myocardial Infarction (AMI)
Phase 3 Active, closed 2024-06 UK, USA, India, China
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
NCT05567796 · Obesity
Phase 3 Active, closed 2022-11 UK, USA, India, China
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
NCT04822181 · Non-alcoholic Steatohepatitis
Phase 3 Active, closed 2021-04 Ireland, UK, USA, India, China
REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels
NCT05669755 · Cardiovascular Disease
Phase 3 Active, closed 2023-03 Ireland, UK, USA, India
A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term
NCT07011667 · Obesity
Drug: CagriSema
Phase 3 Active, closed 2025-06 USA
A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow
NCT05330325 · SGA, Turner Syndrome, Noonan Syndrome, ISS
Phase 3 Active, closed 2022-08 Ireland, UK, USA, India, China
A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A
NCT05685238 · ClinicalTrials.gov ↗ · Haemophilia A, Haemophilia A With Inhibitors
Phase 3 Active, closed 2023-02 Ireland, UK, USA, India, China
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation
NCT06200207 · ClinicalTrials.gov ↗ · Heart Failure, Systemic Inflammation
Phase 3 Active, closed 2024-04 UK, USA, India
A Research Study in Children Born Small and Who Stayed Small. Treatment is Somapacitan Once a Week Compared to Norditropin® Once a Day
NCT03878446 · ClinicalTrials.gov ↗ · Short Stature Children Born Small for Gestational Age (SGA)
Phase 2 Active, closed 2019-07 Ireland, UK, USA, India
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes
NCT03811561 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Type 2
Phase 3 Active, closed 2019-05 UK, USA, India
Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors
NCT04082429 · ClinicalTrials.gov ↗ · Haemophilia A Without Inhibitors, Haemophilia B Without Inhibitors
Phase 3 Active, closed 2019-11 UK, USA, India
STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss
NCT06571383 · ClinicalTrials.gov ↗ · Obesity
Phase 4 Active, closed 2024-09 UK, USA
SCALE KIDS: Research Study to Look at How Well a New Medicine is at Lowering Weight in Children With Obesity
NCT04775082 · ClinicalTrials.gov ↗ · Obesity
Phase 3 Active, closed 2021-03 USA, India
Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitors
NCT04083781 · ClinicalTrials.gov ↗ · Haemophilia A With Inhibitors, Haemophilia B With Inhibitors
Phase 3 Active, closed 2019-10 UK, USA, India
Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With Cagrilintide
NCT07220759 · ClinicalTrials.gov ↗ · Overweight, Obesity, Type 2 Diabetes
Phase 3 Active, closed 2025-11 UK, USA
Weight Loss in People Living With Overweight or Obesity Following Treatment With Cagrilintide
NCT07220642 · ClinicalTrials.gov ↗ · Obesity, Overweight
Phase 3 Active, closed 2025-11 UK, USA
A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With Obesity
NCT06780449 · ClinicalTrials.gov ↗ · Obesity
Phase 3 Active, closed 2025-02 UK, USA
A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight
NCT05726227 · ClinicalTrials.gov ↗ · Obesity
Phase 3 Active, closed 2023-07 UK, USA
AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss
NCT07503210 · ClinicalTrials.gov ↗ · Obesity
Phase 3 Active, closed 2026-04 UK, USA
A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or Obesity
NCT06577766 · ClinicalTrials.gov ↗ · Obesity, Overweight
Phase 1 Active, closed 2024-09 USA
A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes
NCT07076199 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Type 1
Phase 3 Active, closed 2025-08 USA
A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet
NCT07184086 · ClinicalTrials.gov ↗ · Obesity
Phase 1 Active, closed 2025-09 USA
A Research Study on How Well Different Doses of the Medicine NNC0662-0419 Help People Living With Overweight or Obesity
NCT07184632 · ClinicalTrials.gov ↗ · Overweight, Obesity
Phase 2 Active, closed 2025-10 USA
A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity
NCT07639021 · ClinicalTrials.gov ↗ · Obesity
Phase 2 Active, closed 2026-06 USA
A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9
NCT05723835 · ClinicalTrials.gov ↗ · SGA, Turner Syndrome, Noonan Syndrome
Phase 3 Active, closed 2023-02 USA
A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis
NCT06260709 · ClinicalTrials.gov ↗ · Transthyretin Amyloid Cardiomyopathy (ATTR CM)
Phase 2 Active, closed 2024-02 USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Novo Nordisk in the EU trials register (CTIS)

11 trials

Authorised or ongoing trials in the EU Clinical Trials Information System with Novo Nordisk as sponsor. Some are the same study as a ClinicalTrials.gov record above; the two registries share no common ID. Trials with a site in Ireland are listed first.

StudyPhaseStatusCountries
A global phase 3 randomised, double-blind and placebo-controlled study evaluating the efficacy and safety of etavopivat in children with sickle cell disease
2025-524464-38-00 · Hemic and Lymphatic Diseases
Phase 3 Authorised France, Netherlands
Zenagamtide use for the reduction of risk of major adverse cardiovascular events in people with established atherosclerotic cardiovascular disease and either overweight or obesity (AMBIENCE)
2026-525182-53-00 · Cardiovascular Diseases
Phase 3 Authorised Denmark, Czechia, Greece + 6 more
A study assessing the safety, tolerability, pharmacokinetics and efficacy of single and multiple doses of NNC0638-0355 in participants with overweight or obesity
2026-526797-16-00 · Nutritional and Metabolic Diseases
Phase 1 Authorised Netherlands
A research study looking into how a high dose of s.c. semaglutide works with emptying of the stomach in people with excess body weight
2026-526083-20-00 · Nutritional and Metabolic Diseases
Phase 1 Authorised Austria
A research study looking at the effect of timing of meal after dosing and water volume at dosing on how the medicine zenagamtide is taken up by the body of participants with overweight or obesity
2025-521383-35-00 · Not possible to specify
Phase 1 Authorised Germany
Efficacy and safety of NNC0487-0111 s.c. once-weekly compared to semaglutide s.c. once-weekly in participants with overweight or obesity, and type 2 diabetes (AMAZE 8)
2024-520446-31-00 · CTIS ↗ · Nutritional and Metabolic Diseases
Phase 3 Ongoing Germany, Croatia, Portugal + 4 more
Efficacy and safety of NNC0487-0111 s.c. once-weekly in participants with overweight or obesity, and type 2 diabetes (AMAZE 2)
2024-520441-23-00 · CTIS ↗ · Nutritional and Metabolic Diseases
Phase 3 Ongoing Italy, Croatia, Hungary + 2 more
Efficacy, safety and pharmacokinetics of cagrilintide s.c. 2.4 mg as monotherapy and in combination with semaglutide s.c. 2.4 mg (CagriSema) once weekly for weight management in children and adolescents with overweight or obesity
2023-509176-42-00 · CTIS ↗ · Nutritional and Metabolic Diseases
Phase 3 Ongoing Slovakia, Austria, Spain + 11 more
Protocol Title: Efficacy and safety of once-weekly subcutaneous NNC0662-0419 in participants with type 2 diabetes – a dose-finding study
2025-523260-20-00 · CTIS ↗ · Hormonal diseases
Phase 2 Ongoing Spain, Hungary, Portugal + 3 more
A Single Arm, Open Label, Phase 1/2 Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients with Sickle Cell Disease
2024-519881-32-00 · CTIS ↗ · Hemic and Lymphatic Diseases
Phase 1 Authorised France
EFFectiveness of once-weekly insulin ICodec versus once-daily basal Insulin analogues in an insulin-naïve type 2 diabEtes population in real-world cliNical pracTice- The EFFICIENT pragmatic study
2024-520068-32-00 · CTIS ↗ · Nutritional and Metabolic Diseases
Phase 4 Authorised Germany, Italy
03

Drugs in Novo Nordisk trials

20 compounds

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

04

Conditions in Novo Nordisk trials

48 conditions
Obesity39Overweight25Diabetes Mellitus, Type 28Heart Failure5Type 2 Diabetes4Haemophilia A3Healthy Volunteers3Haemophilia A With Inhibitors2Transthyretin Amyloid Cardiomyopathy (ATTR CM)2Cardiovascular Risk2Pregnancy2Sickle Cell Disease2Haemophilia B2Medullary Thyroid Carcinoma2Obstructive Sleep Apnoea2Non-alcoholic Steatohepatitis1Cardiovascular Disease1SGA, Turner Syndrome, Noonan Syndrome, ISS1Short Stature Children Born Small for Gestational Age (SGA)1Haemophilia A and B With and Without Inhibitors1Acute Myocardial Infarction (AMI)1Growth Hormone Deficiency1Neoplasms1Diabetes Mellitus Type 21
05

By trial register

RegisterTrialsRecruiting
Clinical trials in USA6930
Clinical trials in UK3813
Clinical trials in India2912
Clinical trials in China147
Clinical trials in Ireland61
EU register (CTIS)11—

A trial with sites in more than one country appears in each of those registers.

06

Other sponsors in Obesity

SponsorTrials
Eli Lilly and Company39
Amgen7
China-Japan Friendship Hospital6
Kailera5
Innovent Biologics (Suzhou)5
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School4
Hangzhou Sciwind Biosciences4
Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics3
Peking University Third Hospital3
Chinese Academy of Sciences3

Sponsors with the most current trials registered for this condition.

07

Questions about Novo Nordisk trials

How many clinical trials does Novo Nordisk sponsor?

Novo Nordisk is the lead sponsor of 83 current trials on ClinicalTrials.gov in our USA, UK, India, China and Ireland registers, and 11 authorised or ongoing trials in the EU register (CTIS), as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Novo Nordisk trials recruiting?

Yes. 36 of its 83 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is Novo Nordisk testing?

Its current trials name 20 drugs and biologicals as interventions. The most frequent are Semaglutide (22), Cagrilintide (10), NNC0487-0111 (9), CagriSema (4) and NNC0662-0419 (4). The number in brackets is how many of its trials name each drug.

Does Novo Nordisk have clinical trials in Ireland?

Yes. 6 trials in our Ireland register (ClinicalTrials.gov). Some may be the same study registered in both. See the Irish clinical trials register for sites and contacts.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.