AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
NCT07509307 · Obesity, Overweight, Osteoarthritis, Knee
|
Phase 3 |
Recruiting |
2026-04 |
USA |
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
NCT07207811 · ClinicalTrials.gov ↗ · Transthyretin Amyloid Cardiomyopathy (ATTR CM)
|
Phase 3 |
Recruiting |
2025-10 |
Ireland, UK, USA, China |
AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
NCT07571005 · ClinicalTrials.gov ↗ · Obesity, Overweight, Obstructive Sleep Apnoea
|
Phase 3 |
Recruiting |
2026-05 |
USA, India, China |
AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
NCT07571109 · ClinicalTrials.gov ↗ · Obesity, Overweight, Obstructive Sleep Apnoea
|
Phase 3 |
Recruiting |
2026-05 |
USA, India, China |
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
NCT07567001 · ClinicalTrials.gov ↗ · Obesity, Heart Failure
|
Phase 3 |
Recruiting |
2026-05 |
UK, USA, India, China |
|
A Study Looking at How Weekly Injections of Two Hormones - GIP and Amylin - Affect Stomach-related Side Effects in People Who Are Overweight or Obese
|
Phase 1 |
Recruiting |
2026-02 |
UK |
|
A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy
|
Phase 2 |
Recruiting |
2025-06 |
UK, India |
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
NCT06609226 · ClinicalTrials.gov ↗ · Sickle Cell Disease, Thalassemia
|
Phase 3 |
Recruiting |
2025-01 |
UK, USA, India |
|
A Research Study on the Effects of NNC0537-1482 in Participants With Heart Failure
|
Phase 1 |
Recruiting |
2025-10 |
UK |
A Research Study to See How Safe is Eptacog Alfa When Used to Stop Heavy Bleeding in Women After Giving Birth in India
NCT07157423 · ClinicalTrials.gov ↗ · Severe Postpartum Haemorrhage
|
Phase 4 |
Recruiting |
2025-08 |
India |
|
A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity
|
Phase 1 |
Recruiting |
2026-08 |
USA |
A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease
NCT06612268 · ClinicalTrials.gov ↗ · Sickle Cell Disease
|
Phase 3 |
Recruiting |
2025-02 |
UK, USA, India |
A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
NCT06717698 · ClinicalTrials.gov ↗ · Chronic Kidney Disease
|
Phase 2 |
Recruiting |
2024-12 |
USA, India |
|
Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight
|
Phase 3 |
Recruiting |
2026-08 |
USA |
|
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
|
Phase 2 |
Recruiting |
2025-06 |
UK, USA, India |
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
NCT07253285 · ClinicalTrials.gov ↗ · Overweight, Obesity
|
Phase 3 |
Recruiting |
2026-01 |
UK, USA, India, China |
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
NCT07797335 · ClinicalTrials.gov ↗ · Type 2 Diabetes, Cardiovascular Risk
|
Phase 3 |
Recruiting |
2026-08 |
UK, USA, India, China |
|
A Research Study Looking at How Different Doses of Study Medicine (Inno8) Work in the Body of People With Haemophilia A
|
Phase 1 |
Recruiting |
2025-10 |
UK, USA |
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes
NCT07282613 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Type 2
|
Phase 3 |
Recruiting |
2026-08 |
USA, India |
|
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
|
Phase 2 |
Recruiting |
2026-06 |
USA |
|
AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight
|
Phase 3 |
Recruiting |
2026-02 |
UK, USA |
Multiple Dose Study for a New Medication to Potentially Treat Liver Diseases
NCT06891365 · ClinicalTrials.gov ↗ · Healthy Volunteers, Hepatic Steatosis
|
Phase 1 |
Recruiting |
2025-03 |
UK |
|
Management Concepts of Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) Among Chinese Physicians
|
Observational |
Recruiting |
2026-06 |
China |
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes
NCT07415954 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Type 2
|
Phase 2 |
Recruiting |
2026-04 |
USA |
A Research Study Looking Into How NNC0662-0419 Works With Birth Control Pills and Emptying of the Stomach in Women Not Able to Become Pregnant With Excess Body Weight
NCT07525791 · ClinicalTrials.gov ↗ · Overweight, Obesity
|
Phase 1 |
Recruiting |
2026-04 |
USA |
A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity
NCT07395687 · ClinicalTrials.gov ↗ · Overweight, Obesity
|
Phase 2 |
Recruiting |
2026-02 |
USA |
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
NCT07564414 · ClinicalTrials.gov ↗ · Obesity, Type 2 Diabetes
|
Phase 3 |
Recruiting |
2026-05 |
USA |
A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body Weight
NCT07710768 · ClinicalTrials.gov ↗ · Obesity, Overweight
|
Phase 1 |
Recruiting |
2026-07 |
USA |
A Study to See How Safe a New Medicine (NNC6989-0001) is in Healthy People Living With Overweight or Obesity
NCT07437079 · ClinicalTrials.gov ↗ · Overweight, Obesity
|
Phase 1 |
Recruiting |
2026-02 |
USA |
A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity
NCT07566390 · ClinicalTrials.gov ↗ · Obesity, Overweight
|
Phase 1 |
Recruiting |
2026-05 |
USA |
AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
NCT07533175 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Overweight, Obesity
|
Phase 3 |
Recruiting |
2026-04 |
USA |
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
NCT07481630 · ClinicalTrials.gov ↗ · Obesity, Knee Osteoarthritis (OA)
|
Phase 3 |
Recruiting |
2026-04 |
USA |
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events
NCT07607587 · ClinicalTrials.gov ↗ · Obesity, Overweight
|
Phase 1 |
Recruiting |
2026-05 |
USA |
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
NCT07745504 · ClinicalTrials.gov ↗ · Overweight, Obesity
|
Phase 3 |
Recruiting |
2026-08 |
USA |
|
Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)
|
Phase 1 |
Recruiting |
2025-11 |
USA |
A Research Study to Evaluate the Safety of NNC4004-0002 When Given to Participants With Asymptomatic Hyperuricemia
NCT06859073 · ClinicalTrials.gov ↗ · Healthy Volunteers, Hyperuricemia
|
Phase 1 |
Recruiting |
2024-11 |
USA |
AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
NCT07400107 · Obesity, Overweight, Diabetes Mellitus, Type 2
|
Phase 3 |
Not yet open |
2026-05 |
USA, India |
|
A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A
|
Phase 3 |
Not yet open |
2026-10 |
UK, USA, India |
AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose Weight
NCT07668401 · ClinicalTrials.gov ↗ · Obesity, Overweight
|
Phase 3 |
Not yet open |
2027-01 |
India |
Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema
NCT07817251 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Type 2
|
Phase 3 |
Not yet open |
2026-09 |
USA |
A Study to See How Safe a New Medicine (NNC0642-1895) is in Healthy People
NCT07829406 · ClinicalTrials.gov ↗ · Healthy Volunteers
|
Phase 1 |
Not yet open |
2026-09 |
USA |
AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight
NCT07720271 · ClinicalTrials.gov ↗ · Overweight, Obesity
|
Phase 3 |
Not yet open |
2026-09 |
USA |
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide
NCT07668414 · ClinicalTrials.gov ↗ · Overweight, Obesity
|
Phase 3 |
Not yet open |
2026-09 |
USA |
|
Defeat Rare Disease in Asia and Pacific (APAC) DRDA - Haemophilia
|
Observational |
By invitation |
2025-01 |
India |
A Study to Follow Paediatric Participants With Growth Hormone Deficiency Treated With Somapacitan for Long Term Safety Information and Clinical Parameters
NCT06709040 · Growth Hormone Deficiency, Neoplasms, Diabetes Mellitus Type 2
|
Observational |
By invitation |
2024-12 |
UK |
|
A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Information
|
Observational |
By invitation |
2023-02 |
USA |
|
An Observational Study of Patients With Moderate Parkinson's Disease
|
Observational |
By invitation |
2023-04 |
UK, USA |
|
A Two-year Prospective, Observational Study of Wegovy in Real-world Clinical Practice
|
Observational |
By invitation |
2025-05 |
UK |
A Study to Evaluate Safety of Exposure to Wegovy During Pregnancy
NCT05872022 · ClinicalTrials.gov ↗ · Pregnancy, Obesity, Overweight
|
Observational |
By invitation |
2023-07 |
UK, USA |
|
A Study Following Males With Haemophilia B on Prophylaxis With Refixia/REBINYN
|
Observational |
By invitation |
2019-04 |
UK |
|
Adverse Event Data Collection From External Registries on Nonacog Beta Pegol
|
Observational |
By invitation |
2018-10 |
UK |
Database Linkage Study to Evaluate the Risk of Medullary Thyroid Carcinoma
NCT07713901 · ClinicalTrials.gov ↗ · Medullary Thyroid Carcinoma
|
Observational |
By invitation |
2025-12 |
USA |
An Active Surveillance Program for Cases of Medullary Thyroid Carcinoma (MTC)
NCT01511393 · ClinicalTrials.gov ↗ · Diabetes, Diabetes Mellitus, Type 2, Medullary Thyroid Carcinoma
|
Observational |
By invitation |
2012-01 |
USA |
A Study to Evaluate the Safety of Exposure to Wegovy During Pregnancy
NCT05503927 · ClinicalTrials.gov ↗ · Pregnancy, Obesity, Overweight
|
Observational |
By invitation |
2020-02 |
USA |
Research Study to Examine Blood Sugar Control, Treatment Satisfaction and Adherence in People With Type 2 Diabetes After Switching From Daily Basal Insulin to Once-weekly Insulin Icodec
NCT07658417 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Type 2
|
Observational |
By invitation |
2026-07 |
China |
|
A Two-armed Real-world Study of Ozempic (OW Semaglutide) to Evaluate Its Adherence and Persistence Compared With Other Anti-diabetic Drugs Among Adult T2DM Patients in China
|
Observational |
By invitation |
2026-02 |
China |
A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors
NCT05135559 · Haemophilia A and B With and Without Inhibitors
|
Phase 3 |
Active, closed |
2022-03 |
UK, USA, India |
ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack
NCT06118281 · Cardiovascular Risk, Acute Myocardial Infarction (AMI)
|
Phase 3 |
Active, closed |
2024-06 |
UK, USA, India, China |
|
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
|
Phase 3 |
Active, closed |
2022-11 |
UK, USA, India, China |
|
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
|
Phase 3 |
Active, closed |
2021-04 |
Ireland, UK, USA, India, China |
|
REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels
|
Phase 3 |
Active, closed |
2023-03 |
Ireland, UK, USA, India |
|
A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term
|
Phase 3 |
Active, closed |
2025-06 |
USA |
A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow
NCT05330325 · SGA, Turner Syndrome, Noonan Syndrome, ISS
|
Phase 3 |
Active, closed |
2022-08 |
Ireland, UK, USA, India, China |
A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A
NCT05685238 · ClinicalTrials.gov ↗ · Haemophilia A, Haemophilia A With Inhibitors
|
Phase 3 |
Active, closed |
2023-02 |
Ireland, UK, USA, India, China |
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation
NCT06200207 · ClinicalTrials.gov ↗ · Heart Failure, Systemic Inflammation
|
Phase 3 |
Active, closed |
2024-04 |
UK, USA, India |
A Research Study in Children Born Small and Who Stayed Small. Treatment is Somapacitan Once a Week Compared to Norditropin® Once a Day
NCT03878446 · ClinicalTrials.gov ↗ · Short Stature Children Born Small for Gestational Age (SGA)
|
Phase 2 |
Active, closed |
2019-07 |
Ireland, UK, USA, India |
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes
NCT03811561 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Type 2
|
Phase 3 |
Active, closed |
2019-05 |
UK, USA, India |
Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors
NCT04082429 · ClinicalTrials.gov ↗ · Haemophilia A Without Inhibitors, Haemophilia B Without Inhibitors
|
Phase 3 |
Active, closed |
2019-11 |
UK, USA, India |
|
STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss
|
Phase 4 |
Active, closed |
2024-09 |
UK, USA |
|
SCALE KIDS: Research Study to Look at How Well a New Medicine is at Lowering Weight in Children With Obesity
|
Phase 3 |
Active, closed |
2021-03 |
USA, India |
Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitors
NCT04083781 · ClinicalTrials.gov ↗ · Haemophilia A With Inhibitors, Haemophilia B With Inhibitors
|
Phase 3 |
Active, closed |
2019-10 |
UK, USA, India |
Weight Loss in People Living With Overweight or Obesity and Type 2 Diabetes Following Treatment With Cagrilintide
NCT07220759 · ClinicalTrials.gov ↗ · Overweight, Obesity, Type 2 Diabetes
|
Phase 3 |
Active, closed |
2025-11 |
UK, USA |
Weight Loss in People Living With Overweight or Obesity Following Treatment With Cagrilintide
NCT07220642 · ClinicalTrials.gov ↗ · Obesity, Overweight
|
Phase 3 |
Active, closed |
2025-11 |
UK, USA |
|
A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With Obesity
|
Phase 3 |
Active, closed |
2025-02 |
UK, USA |
|
A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight
|
Phase 3 |
Active, closed |
2023-07 |
UK, USA |
|
AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss
|
Phase 3 |
Active, closed |
2026-04 |
UK, USA |
A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or Obesity
NCT06577766 · ClinicalTrials.gov ↗ · Obesity, Overweight
|
Phase 1 |
Active, closed |
2024-09 |
USA |
A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes
NCT07076199 · ClinicalTrials.gov ↗ · Diabetes Mellitus, Type 1
|
Phase 3 |
Active, closed |
2025-08 |
USA |
|
A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet
|
Phase 1 |
Active, closed |
2025-09 |
USA |
A Research Study on How Well Different Doses of the Medicine NNC0662-0419 Help People Living With Overweight or Obesity
NCT07184632 · ClinicalTrials.gov ↗ · Overweight, Obesity
|
Phase 2 |
Active, closed |
2025-10 |
USA |
|
A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity
|
Phase 2 |
Active, closed |
2026-06 |
USA |
A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9
NCT05723835 · ClinicalTrials.gov ↗ · SGA, Turner Syndrome, Noonan Syndrome
|
Phase 3 |
Active, closed |
2023-02 |
USA |
A Research Study to Look at Long-term Treatment With a Medicine Called NNC6019-0001 for People Who Have Heart Failure Due to Transthyretin Amyloidosis
NCT06260709 · ClinicalTrials.gov ↗ · Transthyretin Amyloid Cardiomyopathy (ATTR CM)
|
Phase 2 |
Active, closed |
2024-02 |
USA |