Thermal Artifact in Patients Undergoing Conization: A Clinical Study

Condition(s) studied

Investigational drug(s) / intervention(s)

Conization with Electrosurgery diffferent power settings: 50 watts pure cut,50 watts blend mode

Study summary

Cervical transformation zone excision is commonly used in the diagnosis and treatment of cervical intraepithelial neoplasia. Thermal artifacts can negatively affect histopathological evaluation. This study compares three different modifications of conization performed using electrosurgery in terms of the degree of thermal artifacts.

Eligibility

Primary outcome measure(s)

• Thermal Artefact — Within 7 days following the surgical procedure
  Thermal artifact will be assessed by blinded gynecologic pathologists using a structured histopathological evaluation based on epithelial distortion, coagulative necrosis, and interference with margin interpretation. Thermal artifact severity will be graded as none, mild, moderate, or severe.

Trial sites (1)

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