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Compound · clinical trials

Dabrafenib clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 11 trials in our China, USA, UK and India registers that name Dabrafenib as an intervention. Synced 25 Sep 2026
11Current trials
6Recruiting now
8Lead sponsors
4Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Dabrafenib is named as an intervention in 11 current clinical trials in our China, USA, UK and India registers. 6 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Novartis Pharmaceuticals (3). The most-studied condition is Solid Tumor.

Trials by status

  • Recruiting655%
  • Not yet open218%
  • Active, closed327%

Trials by phase

  • Phase 2655%
  • Phase 4327%
  • Phase 1/219%
  • Phase 319%
01

Clinical trials of Dabrafenib

11 trials
StudyPhaseStatusLead sponsorRegisters
Dabrafenib and/or Trametinib Rollover Study
NCT03340506 · ClinicalTrials.gov ↗ · Melanoma, Non Small Cell Lung Cancer, Solid Tumor
Phase 4 Recruiting Novartis Pharmaceuticals USA, China
Efficacy of Organoid-Based Drug Screening to Guide Treatment for Locally Advanced Thyroid Cancer
NCT06482086 · ClinicalTrials.gov ↗ · Locally Advanced Thyroid Gland Carcinoma
Phase 2 Recruiting West China Hospital China
Neoadjuvant Umbrella Trial for Patients With Unresectable Stage III NSCLC Harboring Rare Mutations.
NCT06563999 · ClinicalTrials.gov ↗ · Lung Cancer Stage III, Mutation
Phase 2 Recruiting Sun Yat-sen University China
Precision Medicine Trial Based on Molecular Matching Therapy for Patients With Standard Treatment Exhaustion
NCT06739395 · ClinicalTrials.gov ↗ · Solid Tumor, Precision Medicine
Phase 2 Recruiting Tianjin Medical University Second Hospital China
Real-world Study of Darafenib or Trametinib and Clofarabine for High-risk/Recurrent/Refractory Langerhans Cell Histiocytosis in Children
NCT07022834 · ClinicalTrials.gov ↗ · Langerhans Cell Histiocytosis (LCH)
Phase 2 Recruiting West China Second University Hospital China
A Phase II Study of Sintilimab Combined With Ipilimumab N01, Cetuximab and Dabrafenib in Patients With Microsatellite-Stable, BRAF V600E-Mutated Metastatic Colorectal Cancer
NCT07506109 · ClinicalTrials.gov ↗ · BRAF V600E, Colorectal Cancer, Sintilimab
Phase 2 Recruiting Tianjin Medical University Cancer Institute and Hospital China
Genotype-Driven Neoadjuvant Therapy for Locally Advanced Thyroid Cancer: A Real-World Cohort Study
NCT07010393 · ClinicalTrials.gov ↗ · Thyroid Neoplasms
Phase 4 Not yet open Fujian Medical University China
Neoadjuvant and Adjuvant Targeted Treatment in NSCLC With BRAF V600 or MET Exon 14 Mutations
NCT06054191 · ClinicalTrials.gov ↗ · NSCLC, BRAF V600 Mutation, MET Exon 14 Mutation
Phase 2 Not yet open Sun Yat-sen University China
Pediatric Long-Term Follow-up and Rollover Study
NCT03975829 · ClinicalTrials.gov ↗ · Diffuse Astrocytoma, Anaplastic Astrocytoma, Astrocytoma
Phase 4 Active, closed Novartis Pharmaceuticals UK, USA
Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer
NCT04940052 · ClinicalTrials.gov ↗ · Differentiated Thyroid Cancer (DTC)
Phase 3 Active, closed Novartis Pharmaceuticals USA, India, China
A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors
NCT05585320 · Advanced Solid Tumor, Pancreatic Adenocarcinoma, Malignant Melanoma (Cutaneous)
Phase 1/2 Active, closed Immuneering Corporation USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Dabrafenib

26 conditions
Solid Tumor2Diffuse Astrocytoma1Anaplastic Astrocytoma1Astrocytoma1Oligodendroglioma, Childhood1Advanced Solid Tumor1Pancreatic Adenocarcinoma1Malignant Melanoma (Cutaneous)1Non-small Cell Lung Cancer (NSCLC)1Differentiated Thyroid Cancer (DTC)1Melanoma1Non Small Cell Lung Cancer1
All 26 conditions
Condition (as registered)Trials
Solid Tumor2
Diffuse Astrocytoma1
Anaplastic Astrocytoma1
Astrocytoma1
Oligodendroglioma, Childhood1
Advanced Solid Tumor1
Pancreatic Adenocarcinoma1
Malignant Melanoma (Cutaneous)1
Non-small Cell Lung Cancer (NSCLC)1
Differentiated Thyroid Cancer (DTC)1
Melanoma1
Non Small Cell Lung Cancer1
Rare Cancers1
Lung Cancer Stage III1
Mutation1
BRAF V600E1
Colorectal Cancer1
Sintilimab1
MSS (Microsatellite Stable)1
Precision Medicine1
Thyroid Neoplasms1
Langerhans Cell Histiocytosis (LCH)1
NSCLC1
BRAF V600 Mutation1
MET Exon 14 Mutation1
Locally Advanced Thyroid Gland Carcinoma1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Novartis Pharmaceuticals3
Sun Yat-sen University2
Immuneering Corporation1
Tianjin Medical University Cancer Institute and Hospital1
Tianjin Medical University Second Hospital1
Fujian Medical University1
West China Second University Hospital1
West China Hospital1
04

By country register

RegisterTrialsRecruiting
Clinical trials in China96
Clinical trials in USA41
Clinical trials in UK10
Clinical trials in India10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Dabrafenib trials

How many clinical trials are testing Dabrafenib?

11 current trials in our China, USA, UK and India registers name Dabrafenib as a drug or biological intervention, as of the registry sync on 25 September 2026. Completed and withdrawn studies are not counted.

Are Dabrafenib trials recruiting patients?

Yes. 6 of the 11 trials are recruiting: 6 with sites in China and 1 with sites in USA. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Dabrafenib clinical trials?

Novartis Pharmaceuticals (3), Sun Yat-sen University (2), Immuneering Corporation (1) and Tianjin Medical University Cancer Institute and Hospital (1), among 8 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Dabrafenib works or whether it is effective, and it is not medical advice.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Dabrafenib works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Dabrafenib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 25 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.