Lidocaine %2 ampoule: Patients who were administered 40 mg lidocaine.
Dexmedetomidine: Patients who were administered 0.25 mg/kg dexmedetomidine.
paracetamol: Patients who were administered 50 mg paracetamol.
Study summary
Propofol and rocuronium may cause pain during intravenous injection. Various pharmacological agents are used to reduce the incidence and severity of injection pain. Among the most commonly used agents for this purpose are lidocaine, various opioids, ketamine, paracetamol, and dexmedetomidine. The aim of this study was to evaluate the comparative effect of intravenous dexmedetomidine and paracetamol versus lidocaine in preventing propofol- and rocuronium-induced pain during anesthesia induction.
Eligibility
Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
Accepted
Inclusion Criteria:
Patients who will receive propofol and rocuronium 18 - 65 years No psychiatric disorders Elective surgery Those who accept the research No history of allergy to any of the drugs used in the study Patients in American Society of Anesthesiologists (ASA) I and II class
Exclusion Criteria:
Patients with chronic pain syndromes Patients with difficult intravenous access Patients with advanced heart block or heart failure Patients with uncontrolled hypertension (Systolic blood pressure \>160 mmHg)
Primary outcome measure(s)
Rocuronium Withdrawal Movement Score — Immediately after rocuronium injection Score evaluating involuntary withdrawal movements in response to rocuronium injection (0 = No movement, 1 = Movement only at the wrist, 2 = Movement involving the upper arm and shoulder of the injected arm, 3 = Widespread movement in multiple extremities or full-body withdrawal)
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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