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Compound · clinical trials

HD204 clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 13 trials in our Mexico, Israel, Canada, South Korea, Japan, Egypt, India, Poland and Turkey registers that name HD204 as an intervention. Synced 1 Oct 2026
13Current trials
4Recruiting now
4Lead sponsors
9Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

HD204 is named as an intervention in 13 current clinical trials in our Mexico, Israel, Canada, South Korea, Japan, Egypt, India, Poland and Turkey registers. 4 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is National Cancer Institute (NCI) (9). The most-studied condition is Fallopian Tube Endometrioid Adenocarcinoma.

Trials by status

  • Recruiting431%
  • Active, closed969%

Trials by phase

  • Phase 31185%
  • Phase 2/318%
  • Phase 218%
01

Clinical trials of HD204

13 trials
StudyPhaseStatusLead sponsorRegisters
Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer
NCT06580314 · ClinicalTrials.gov ↗ · Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube High Grade Serous Adenocarcinoma, Fallopian Tube Malignant Mixed Mesodermal (Mullerian) Tumor
Phase 3 Recruiting NRG Oncology Mexico, Japan
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
NCT07166406 · ClinicalTrials.gov ↗ · Advanced Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8
Phase 3 Recruiting NRG Oncology Canada, Mexico
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
NCT07198074 · ClinicalTrials.gov ↗ · Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma
Phase 3 Recruiting National Cancer Institute (NCI) Mexico
Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial
NCT07271355 · ClinicalTrials.gov ↗ · Metastatic Appendix Carcinoma, Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Peritoneum
Phase 3 Recruiting City of Hope Medical Center Egypt
Doxorubicin Hydrochloride, Cyclophosphamide, and Paclitaxel With or Without Bevacizumab in Treating Patients With Lymph Node-Positive or High-Risk, Lymph Node-Negative Breast Cancer
NCT00433511 · ClinicalTrials.gov ↗ · Breast Adenocarcinoma
Phase 3 Active, closed National Cancer Institute (NCI) Mexico, Israel
Carboplatin, Paclitaxel and Gemcitabine Hydrochloride With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian, Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
NCT00565851 · ClinicalTrials.gov ↗ · Clear Cell Adenocarcinoma, Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma
Phase 3 Active, closed National Cancer Institute (NCI) Mexico, Japan, South Korea
Octreotide Acetate and Recombinant Interferon Alfa-2b or Bevacizumab in Treating Patients With Metastatic or Locally Advanced, High-Risk Neuroendocrine Tumor
NCT00569127 · ClinicalTrials.gov ↗ · Colorectal Neuroendocrine Tumor G1, Gastric Neuroendocrine Tumor G1, Neuroendocrine Neoplasm
Phase 3 Active, closed National Cancer Institute (NCI) Mexico, Israel
Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
NCT00588770 · ClinicalTrials.gov ↗ · Neck Squamous Cell Carcinoma of Unknown Primary, Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma
Phase 3 Active, closed National Cancer Institute (NCI) Mexico, Israel
Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine With or Without Bevacizumab as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II-IV or Recurrent Stage I Epithelial Ovarian or Fallopian Tube Cancer
NCT01081262 · ClinicalTrials.gov ↗ · Borderline Ovarian Mucinous Tumor, Ovarian Mucinous Cystadenocarcinoma, Recurrent Fallopian Tube Carcinoma
Phase 3 Active, closed National Cancer Institute (NCI) Mexico
Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
NCT01167712 · ClinicalTrials.gov ↗ · Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube Mucinous Adenocarcinoma, Fallopian Tube Transitional Cell Carcinoma
Phase 3 Active, closed National Cancer Institute (NCI) Canada, Mexico, South Korea, Israel
A Trial to Compare the Efficacy, Safety, Pharmacokinetics and Immunogenicity of HD204 to Avastinยฎ in Advanced Non-squamous Non-small Cell Lung Cancer Patients
NCT03390686 · ClinicalTrials.gov ↗ · Lung Cancer, Non-small Cell Lung Cancer
Phase 3 Active, closed Prestige Biopharma Limited India, Poland, Turkey
Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT02839707 · ClinicalTrials.gov ↗ · Fallopian Tube High Grade Serous Adenocarcinoma, Ovarian High Grade Serous Adenocarcinoma, Ovarian Seromucinous Carcinoma
Phase 2/3 Active, closed National Cancer Institute (NCI) Mexico, Israel, Egypt
Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer
NCT00977574 · ClinicalTrials.gov ↗ · Endometrial Adenocarcinoma, Endometrial Adenosquamous Carcinoma, Endometrial Clear Cell Adenocarcinoma
Phase 2 Active, closed National Cancer Institute (NCI) Mexico

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with HD204

40 conditions
Fallopian Tube Endometrioid Adenocarcinoma3Fallopian Tube Mucinous Adenocarcinoma2Fallopian Tube High Grade Serous Adenocarcinoma2Lung Cancer1Non-small Cell Lung Cancer1Advanced Hepatocellular Carcinoma1Stage III Hepatocellular Carcinoma AJCC v81Stage IV Hepatocellular Carcinoma AJCC v81Fallopian Tube Transitional Cell Carcinoma1Ovarian Brenner Tumor1Neck Squamous Cell Carcinoma of Unknown Primary1Recurrent Hypopharyngeal Squamous Cell Carcinoma1
All 40 conditions
Condition (as registered)Trials
Fallopian Tube Endometrioid Adenocarcinoma3
Fallopian Tube Mucinous Adenocarcinoma2
Fallopian Tube High Grade Serous Adenocarcinoma2
Lung Cancer1
Non-small Cell Lung Cancer1
Advanced Hepatocellular Carcinoma1
Stage III Hepatocellular Carcinoma AJCC v81
Stage IV Hepatocellular Carcinoma AJCC v81
Fallopian Tube Transitional Cell Carcinoma1
Ovarian Brenner Tumor1
Neck Squamous Cell Carcinoma of Unknown Primary1
Recurrent Hypopharyngeal Squamous Cell Carcinoma1
Recurrent Laryngeal Squamous Cell Carcinoma1
Recurrent Laryngeal Verrucous Carcinoma1
Colorectal Neuroendocrine Tumor G11
Gastric Neuroendocrine Tumor G11
Neuroendocrine Neoplasm1
Neuroendocrine Tumor1
Clear Cell Adenocarcinoma1
Fallopian Tube Clear Cell Adenocarcinoma1
Ovarian High Grade Serous Adenocarcinoma1
Ovarian Seromucinous Carcinoma1
Primary Peritoneal High Grade Serous Adenocarcinoma1
Fallopian Tube Malignant Mixed Mesodermal (Mullerian) Tumor1
FIGO Stage III Ovarian Cancer 20141
Breast Adenocarcinoma1
Endometrial Adenocarcinoma1
Endometrial Adenosquamous Carcinoma1
Endometrial Clear Cell Adenocarcinoma1
Endometrial Serous Adenocarcinoma1
Borderline Ovarian Mucinous Tumor1
Ovarian Mucinous Cystadenocarcinoma1
Recurrent Fallopian Tube Carcinoma1
Recurrent Ovarian Carcinoma1
Advanced Endometrial Carcinoma1
Recurrent Endometrial Carcinoma1
Metastatic Appendix Carcinoma1
Metastatic Colorectal Carcinoma1
Metastatic Malignant Neoplasm in the Peritoneum1
Stage IV Appendix Carcinoma AJCC v81
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
National Cancer Institute (NCI)9
NRG Oncology2
Prestige Biopharma Limited1
City of Hope Medical Center1
04

By country register

RegisterTrialsRecruiting
Clinical trials in Mexico113
Clinical trials in Israel50
Clinical trials in Canada21
Clinical trials in South Korea20
Clinical trials in Japan21
Clinical trials in Egypt21
Clinical trials in India10
Clinical trials in Poland10
Clinical trials in Turkey10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about HD204 trials

How many clinical trials are testing HD204?

13 current trials in our Mexico, Israel, Canada, South Korea, Japan, Egypt, India, Poland and Turkey registers name HD204 as a drug or biological intervention, as of the registry sync on 1 October 2026. Completed and withdrawn studies are not counted.

Are HD204 trials recruiting patients?

Yes. 4 of the 13 trials are recruiting: 3 with sites in Mexico, 1 with sites in Canada, 1 with sites in Japan and 1 with sites in Egypt. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors HD204 clinical trials?

National Cancer Institute (NCI) (9), NRG Oncology (2), Prestige Biopharma Limited (1) and City of Hope Medical Center (1). The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how HD204 works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how HD204 works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists HD204 (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 1 Oct 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.