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Priya Life Science Compound trial record
Compound · clinical trials

Cediranib Maleate clinical trials

Also listed in trial records as Cediranib, Recentin, AZD2171, AZD2171 Maleate, AZ-D2171, AZD 2171
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 10 trials in our Canada, Israel, Mexico, South Korea, Japan, Egypt, UK, USA, Germany, France, Spain and Austria registers that name Cediranib Maleate as an intervention. Synced 13 Nov 2026
10Current trials
0Recruiting now
3Lead sponsors
12Country registers
At a glance

Cediranib Maleate is named as an intervention in 10 current clinical trials in our Canada, Israel, Mexico, South Korea, Japan, Egypt, UK, USA, Germany, France, Spain and Austria registers. None are recruiting at the moment. The most common phase is Phase 2. The sponsor with the most trials is National Cancer Institute (NCI) (7). The most-studied condition is Fallopian Tube Clear Cell Adenocarcinoma.

Where Cediranib Maleate is approved

All regulators →
USUnited States (FDA)
No FDA approval of a single-substance product in Drugs@FDA
First original NDA/BLA approval
EUEuropean Union (EMA)
No centralised EU authorisation (it may be authorised nationally)
First centralised authorisation
CACanada (Health Canada)
No new-drug Notice of Compliance since 1994
First new-drug NOC

From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.

How Cediranib Maleate works

All drug targets →
  • Inhibits KIT Primary target
    Target: KIT KIT proto-oncogene, receptor tyrosine kinase
    Guide to Pharmacology only
  • Inhibits PDGFRA Primary target
    Target: PDGFRA platelet derived growth factor receptor alpha
    Guide to Pharmacology only
  • Inhibits FLT1 Primary target
    Target: FLT1 fms related receptor tyrosine kinase 1
    Guide to Pharmacology only
  • Inhibits FLT4 Primary target
    Target: FLT4 fms related receptor tyrosine kinase 4
    Guide to Pharmacology only
  • Inhibits KDR Primary target
    Target: KDR kinase insert domain receptor
    Guide to Pharmacology only
  • Inhibits PDGFRB Primary target
    Target: PDGFRB platelet derived growth factor receptor beta
    Guide to Pharmacology only
Diseases it has been tested for in clinical trials, by furthest phase
  • Fallopian tube cancerPhase 2/3
  • Non-small cell lung carcinomaPhase 2/3
  • Ovarian cancerPhase 2/3
  • Primary peritoneal carcinomaPhase 2/3
  • B-cell chronic lymphocytic leukemiaPhase 2
  • Acute myeloid leukemiaPhase 2
  • Breast cancerPhase 2
  • Cervical cancerPhase 2
  • Endometrial cancerPhase 2
  • Endometrial carcinomaPhase 2
32 diseases in all

Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL2103798, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 5664, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.

Patient leaflets for Cediranib Maleate

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Reference identifiers for Cediranib Maleate

ChEMBL
CHEMBL2103798
PubChem CID
11226834
CAS number
857036-77-2
FDA UNII
68AYS9A614
Wikidata
Q27264241

Codes that identify this medicine in other databases, from Wikidata (CC0), matched by its ChEMBL ID. The ATC code is the WHO classification of what the medicine is used for.

Trials by status

  • Active, closed10100%

Trials by phase

  • Phase 2660%
  • Phase 1110%
  • Phase 2/3110%
  • Phase 3110%
  • Phase 1/2110%
01

Clinical trials of Cediranib Maleate

10 trials
StudyPhaseStatusLead sponsorRegisters
Testing the Use of A Single Drug (Olaparib) or the Combination of Two Drugs (Cediranib and Olaparib) Compared to the Usual Chemotherapy for Women With Platinum Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT02446600 · ClinicalTrials.gov ↗ · Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Transitional Cell Carcinoma, Fallopian Tube Undifferentiated Carcinoma
Phase 3 Active, closed National Cancer Institute (NCI) Canada, Mexico, Japan, South Korea
Testing the Combination of Cediranib and Olaparib in Comparison to Each Drug Alone or Other Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer
NCT02502266 · Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube Serous Adenocarcinoma
Phase 2/3 Active, closed National Cancer Institute (NCI) Canada, Mexico, Japan, South Korea
A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors
NCT02498613 · ClinicalTrials.gov ↗ · Advanced Malignant Solid Neoplasm, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Lung Small Cell Carcinoma
Phase 2 Active, closed National Cancer Institute (NCI) Canada
Testing Two Oral Drugs Combination (Cediranib and Olaparib) Compared to a Single Drug (Olaparib) for Men With Advanced Prostate Cancer
NCT02893917 · Advanced Prostate Adenocarcinoma With Neuroendocrine Differentiation, Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation
Phase 2 Active, closed National Cancer Institute (NCI) Israel
Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy
NCT03334617 · Non-Small Cell Lung Cancer
Phase 2 Active, closed AstraZeneca USA, Germany, France, Spain, Austria, Canada, South Korea, Israel
Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone
NCT03660826 · ClinicalTrials.gov ↗ · Endometrial Adenocarcinoma, Endometrial Mixed Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma
Phase 2 Active, closed National Cancer Institute (NCI) Canada, Mexico, Israel, Egypt
Study of DNA Damage, Angiogenesis, and PD-L1 Inhibitors in Advanced Solid Tumors
NCT03851614 · ClinicalTrials.gov ↗ · Mismatch Repair Proficient Colorectal Cancer, Pancreatic Adenocarcinoma, Leiomyosarcoma
Phase 2 Active, closed University Health Network, Toronto Canada
Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents
NCT04739800 · Fallopian Tube Mucinous Adenocarcinoma, Ovarian Seromucinous Carcinoma, Platinum-Refractory Fallopian Tube Carcinoma
Phase 2 Active, closed National Cancer Institute (NCI) Mexico, Egypt
Cediranib Maleate and Olaparib in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Peritoneal Cancer or Recurrent Triple-Negative Breast Cancer
NCT01116648 · ClinicalTrials.gov ↗ · Fallopian Tube Carcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian High Grade Serous Adenocarcinoma
Phase 1/2 Active, closed National Cancer Institute (NCI) Israel
Study of the Effect of Rifampicin on the Pharmacokinetics (PK) of Multiple Doses of Cediranib in Patients With Solid Tumours
NCT00750841 · Solid Tumors
Phase 1 Active, closed AstraZeneca UK, Canada

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Cediranib Maleate

31 conditions
Fallopian Tube Clear Cell Adenocarcinoma2Fallopian Tube Transitional Cell Carcinoma2Solid Tumors1Non-Small Cell Lung Cancer1Mismatch Repair Proficient Colorectal Cancer1Pancreatic Adenocarcinoma1Leiomyosarcoma1Fallopian Tube Endometrioid Adenocarcinoma1Fallopian Tube Serous Adenocarcinoma1Advanced Prostate Adenocarcinoma With Neuroendocrine Differentiation1Castration-Resistant Prostate Carcinoma1Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation1
All 31 conditions
Condition (as registered)Trials
Fallopian Tube Clear Cell Adenocarcinoma2
Fallopian Tube Transitional Cell Carcinoma2
Solid Tumors1
Non-Small Cell Lung Cancer1
Mismatch Repair Proficient Colorectal Cancer1
Pancreatic Adenocarcinoma1
Leiomyosarcoma1
Fallopian Tube Endometrioid Adenocarcinoma1
Fallopian Tube Serous Adenocarcinoma1
Advanced Prostate Adenocarcinoma With Neuroendocrine Differentiation1
Castration-Resistant Prostate Carcinoma1
Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation1
Metastatic Prostate Carcinoma1
Endometrial Adenocarcinoma1
Endometrial Mixed Cell Adenocarcinoma1
Endometrial Serous Adenocarcinoma1
Endometrial Undifferentiated Carcinoma1
Advanced Malignant Solid Neoplasm1
Metastatic Lung Non-Small Cell Carcinoma1
Metastatic Lung Small Cell Carcinoma1
Metastatic Pancreatic Adenocarcinoma1
Fallopian Tube Undifferentiated Carcinoma1
Ovarian Clear Cell Adenocarcinoma1
Fallopian Tube Mucinous Adenocarcinoma1
Ovarian Seromucinous Carcinoma1
Platinum-Refractory Fallopian Tube Carcinoma1
Platinum-Refractory Ovarian Carcinoma1
Fallopian Tube Carcinoma1
Ovarian Endometrioid Adenocarcinoma1
Ovarian High Grade Serous Adenocarcinoma1
Ovarian Serous Adenocarcinoma1
05

Related compounds

06

Questions about Cediranib Maleate trials

How many clinical trials are testing Cediranib Maleate?

10 current trials in our Canada, Israel, Mexico, South Korea, Japan, Egypt, UK, USA, Germany, France, Spain and Austria registers name Cediranib Maleate (also registered as AZD2171) as a drug or biological intervention, as of the registry sync on 13 November 2026. Completed and withdrawn studies are not counted.

Are Cediranib Maleate trials recruiting patients?

Not at the moment. None of the 10 trials in our registers is recruiting; they are active but closed to enrolment, not yet open, or enrolling by invitation. Only the study team can confirm whether a patient is eligible.

Who sponsors Cediranib Maleate clinical trials?

National Cancer Institute (NCI) (7), AstraZeneca (2) and University Health Network, Toronto (1). The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Cediranib Maleate works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Cediranib Maleate works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Cediranib Maleate (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 13 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.