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Priya Life Science Compound trial record
Compound · clinical trials

Surufatinib clinical trials

Also listed in trial records as HMPL-012, Sulanda
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 24 trials in our China register that name Surufatinib as an intervention. Synced 10 Nov 2026
24Current trials
13Recruiting now
17Lead sponsors
1Country register
At a glance

Surufatinib is named as an intervention in 24 current clinical trials in our China register. 13 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Sun Yat-sen University (6). The most-studied condition is Neuroendocrine Tumors.

How Surufatinib works

All drug targets →
  • Fibroblast growth factor receptor 1 inhibitor Inhibitor
    Target: FGFR1 fibroblast growth factor receptor 1
    ✓ In ChEMBL and the Guide to Pharmacology
  • Vascular endothelial growth factor receptor inhibitor Inhibitor
    Target: Vascular endothelial growth factor receptor
    ✓ In ChEMBL and the Guide to Pharmacology
Diseases it has been tested for in clinical trials, by furthest phase
  • Malignant pancreatic neoplasmPhase 3
  • Neuroendocrine carcinomaPhase 3
  • Neuroendocrine neoplasmPhase 3
  • Pancreatic neoplasmPhase 3
  • Pancreatic neuroendocrine tumorPhase 3
  • Biliary tract cancerPhase 2/3
  • Rectal cancerPhase 2/3
  • Bile duct adenocarcinomaPhase 2
  • Breast cancerPhase 2
  • CancerPhase 2
36 diseases in all

Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL4297190, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 9769, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.

Patient leaflets for Surufatinib

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting1354%
  • Not yet open417%
  • Active, closed729%

Trials by phase

  • Phase 21771%
  • Phase 1/2313%
  • Phase 414%
  • Observational14%
  • Phase 314%
  • Phase 2/314%
01

Clinical trials of Surufatinib

24 trials
StudyPhaseStatusLead sponsorRegisters
Prospective Multicenter Real-world Study of Surufatinib in Patients With Advanced Neuroendocrine Neoplasms
NCT07272512 · ClinicalTrials.gov ↗ · Neuroendocrine Tumors, Neuroendocrine Neoplasms
Phase 4 Recruiting Shanghai Zhongshan Hospital China
Surufatinib Plus Gemcitabine and Nab-paclitaxel vs. Gemcitabine Plus Nab-paclitaxel in Neoadjuvant Therapy for High - Risk Resectable or Borderline Resectable Pancreatic Cancer
NCT07436741 · ClinicalTrials.gov ↗ · Pancreatic Cancer, Adult
Phase 3 Recruiting Tianjin Medical University Cancer Institute and Hospital China
A Phase II/III Trial to Evaluate the Efficacy and Safety of Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer
NCT06361888 · ClinicalTrials.gov ↗ · Metastatic Pancreatic Cancer
Phase 2/3 Recruiting Hutchmed China
Sintilimab Combined With IBI310 and Surufatinib for the Treatment of G3-NET and NEC (NESSIE)
NCT05165407 · ClinicalTrials.gov ↗ · Neuroendocrine Neoplasm
Phase 2 Recruiting Peking University China
Surufatinib and Sintilimab in Combination With Capecitabine for Metastatic Adenocarcinoma of Small Intestine or Appendix Carcinoma
NCT05472948 · ClinicalTrials.gov ↗ · Adenocarcinoma of Small Intestine, Appendix Carcinoma, Metastatic
Phase 2 Recruiting Sun Yat-sen University China
Surufatinib Combined With Carboplatin/Paclitaxel and Surufatinib Combined With Olaparib as First-line and Maintenance Therapy for Newly Diagnosed High-risk Ovarian Cancer
NCT06437353 · ClinicalTrials.gov ↗ · Ovarian Cancer
Phase 2 Recruiting Anhui Provincial Cancer Hospital China
Phase Ⅱ Clinical Study of Surufatinib Combined With Gemcitabine and Cisplatin Plus Durvalumab/Pembrolizumab Regimen in the Treatment of Advanced Biliary Tract Cancer
NCT06708858 · ClinicalTrials.gov ↗ · Advanced Biliary Tract Cancer
Phase 2 Recruiting Dai, Guanghai China
Combination of Concurrent Chemoradiotherapy With Surufatinib and Tislelizumab in Patients With Locally Advanced Non-Small Cell Lung Cancer
NCT07086456 · Surufatinib, Tislelizumab, Concurrent Chemoradiotherapy
Phase 2 Recruiting Sun Yat-sen University China
Surufatinib Combined With Chemo Versus Surufatinib in the Treatment of Pulmonary Neuroendocrine Tumors
NCT07357623 · ClinicalTrials.gov ↗ · Pulmonary Neuroendocrine Tumor
Phase 2 Recruiting Shanghai Chest Hospital China
Hypofractionated Chemoradiotherapy With Tislelizumab and Surufatinib for Unresectable Stage III NSCLC
NCT07609121 · ClinicalTrials.gov ↗ · NSCLC (Non-small Cell Lung Cancer)
Phase 2 Recruiting Sun Yat-sen University China
Surufatinib Plus Camrelizumab and AS in First Line Treatment of Advanced Metastatic Pancreatic Cancer
NCT05218889 · ClinicalTrials.gov ↗ · Pancreatic Cancer, PDAC - Pancreatic Ductal Adenocarcinoma, Pancreas Cancer
Phase 1/2 Recruiting Chinese PLA General Hospital China
The Combination of Radiotherapy,Surufatinib and Sintilimab in High-Risk Localized Soft Tissue Sarcoma
NCT05839275 · ClinicalTrials.gov ↗ · High-Risk Localized Soft Tissue Sarcoma
Phase 1/2 Recruiting Fudan University China
An Open, Single-center Clinical Study of Surufatinib Combined With Temozolomide and S-1 in the First-line Treatment of Advanced Neuroendocrine Tumors
NCT06038461 · ClinicalTrials.gov ↗ · Neuroendocrine Tumors
Phase 1/2 Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences China
Surufatinib Combined With Gemcitabine Plus Nab-paclitaxel in Locally Advanced Pancreatic Cancer
NCT06361030 · ClinicalTrials.gov ↗ · Pancreatic Cancer, Pancreatic Cancer Non-resectable, Pancreatic Ductal Adenocarcinoma, PDAC
Phase 2 Not yet open Union Hospital, Tongji Medical College, Huazhong University of Science and Technology China
Surufatinib Combined With Serplulimab and Standard Chemotherapy as First-line Treatment in Advanced Solid Tumors With Neuroendocrine Differentiation
NCT06531291 · ClinicalTrials.gov ↗ · ESCC, Biliary Tract Cancer, Gastric Cancer
Phase 2 Not yet open RenJi Hospital China
Surufatinib Plus mFOLFIRINOX and PD-1 Inhibitor as the Neoadjuvant Therapy for High-risk or Borderline Resectable Pancreatic Cancer
NCT07469956 · ClinicalTrials.gov ↗ · Pancreatic Cancer Resectable
Phase 2 Not yet open Sun Yat-sen University China
Surufatinib in Combination With Iparomlimab and Tuvonralimab Injection and AG Chemotherapy for Neoadjuvant Therapy of HRPC or BRPC
NCT07833241 · ClinicalTrials.gov ↗ · Borderline Resectable Pancreatic Cancer, High-Risk Resectable Pancreatic Cancer
Phase 2 Not yet open Shanghai Zhongshan Hospital China
Surufatinib or Surufatinib Combined With Vinorelbine for Non-Small Cell Lung Cancer
NCT04922658 · ClinicalTrials.gov ↗ · Advanced Non-Small Cell Lung Cancer
Phase 2 Active, closed Affiliated Cancer Hospital & Institute of Guangzhou Medical University China
Surufatinib in Patients With Osteosarcoma and Soft Tissue Sarcoma
NCT05106777 · ClinicalTrials.gov ↗ · Sarcoma
Phase 2 Active, closed Sun Yat-sen University China
Surufatinib Combined With Sintilimab and AG in First-line Therapy of Patients With Locally Advanced or Metastatic Pancreatic Cancer
NCT05481476 · ClinicalTrials.gov ↗ · Pancreatic Neoplasms
Phase 2 Active, closed Sun Yat-sen University China
Pamiparib Combined With Surufatinib for the Neoadjuvant Treatment of Unresectable Ovarian Cancer
NCT05652283 · ClinicalTrials.gov ↗ · Ovarian Cancer
Phase 2 Active, closed Bai-Rong Xia China
HAIC Sequential TAE Combined With Tislelizumab and Surufatinib in Unresectable Intrahepatic Cholangiocarcinoma
NCT06239532 · ClinicalTrials.gov ↗ · Intrahepatic Cholangiocarcinoma
Phase 2 Active, closed Qilu Hospital of Shandong University China
Perioperative Surufatinib Plus Sintilimab Combined With Chemotherapy in Gastric/Gastroesophageal Junction Adenocarcinoma
NCT06447636 · ClinicalTrials.gov ↗ · Gastric Cancer, Gastro Esophageal Junction Cancer
Phase 2 Active, closed Fudan University China
Analysis of Optimal Treatment Sequencing of Surufatinib and Somatostatin Analogs in Neuroendocrine Tumors: A Retrospective Cohort Study
NCT07534371 · ClinicalTrials.gov ↗ · Neuroendocrine Tumors
Observational Active, closed West China Hospital China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Surufatinib

33 conditions
All 33 conditions
Condition (as registered)Trials
Neuroendocrine Tumors3
Pancreatic Cancer2
Pancreatic Neoplasms2
Pancreas Cancer2
Ovarian Cancer2
Gastric Cancer2
Pancreatic Cancer Non-resectable1
Pancreatic Ductal Adenocarcinoma, PDAC1
Neuroendocrine Neoplasms1
Sarcoma1
Adenocarcinoma of Small Intestine1
Appendix Carcinoma1
Metastatic1
Neuroendocrine Neoplasm1
NSCLC (Non-small Cell Lung Cancer)1
Intrahepatic Cholangiocarcinoma1
PDAC - Pancreatic Ductal Adenocarcinoma1
Borderline Resectable Pancreatic Cancer1
High-Risk Resectable Pancreatic Cancer1
Advanced Biliary Tract Cancer1
Pancreatic Cancer, Adult1
Surufatinib1
Tislelizumab1
Concurrent Chemoradiotherapy1
Consolidation Therapy1
Pulmonary Neuroendocrine Tumor1
ESCC1
Biliary Tract Cancer1
Gastro Esophageal Junction Cancer1
Advanced Non-Small Cell Lung Cancer1
High-Risk Localized Soft Tissue Sarcoma1
Pancreatic Cancer Resectable1
Metastatic Pancreatic Cancer1
05

Related compounds

06

Questions about Surufatinib trials

How many clinical trials are testing Surufatinib?

24 current trials in our China register name Surufatinib (also registered as HMPL-012) as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.

Are Surufatinib trials recruiting patients?

Yes. 13 of the 24 trials are recruiting: 13 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Surufatinib clinical trials?

Sun Yat-sen University (6), Shanghai Zhongshan Hospital (2), Fudan University (2) and Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1), among 17 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Surufatinib works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Surufatinib works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Surufatinib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.