Clinical trial register · Spain

Clinical Trials in Córdoba, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Spain and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5875 matching records held by the registry are in this view. Synced 11 Oct 2026, 03:18 UTC

5875

Studies in scope

all four open statuses

3096

Recruiting now

open to new participants

1137

Lead sponsors

across recruiting studies

Top sites

Barcelona 3238 Madrid 3046 Valencia 1215 Seville 1054 Málaga 746

Trials with a site in Córdoba

Status

Study

Lead sponsor

Phase

Enrol

Sites in Spain

Start

Recruiting

Immunonutrition vs EPA-DHA Enriched Nutritional Support in Patients With Cancer Undergoing Surgery

NCT07860372Nutrition Aspect of Cancer

Maimónides Biomedical Research Institute of Córdoba

Observational

Córdoba

2026-11-02

Not yet open

A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or Obesity

NCT07861100Cardiovascular Risk, Obesity

DrugZenagamtide

Novo Nordisk A/S

Phase 3

8,500

Marbella, A Coruña, Barcelona, Boadilla del Monte, Cáceres, Córdoba, El Palmar, Granada

2026-10-26

Recruiting

A Study of Complement 3 Glomerulopathy (C3G) Patients Treated With Iptacopan Through an Early Access Program in Spain

NCT07598448Complement 3 Glomerulopathy

Novartis Pharmaceuticals

Observational

Córdoba, Madrid

2026-09-22

Recruiting

FIBRONEER-ACT: A Study to Test Whether Nerandomilast Helps People With Fibrosing Interstitial Lung Disease at Risk for Disease Progression

NCT07540988Interstitial Lung Diseases

DrugNerandomilast

Boehringer Ingelheim

Phase 3

466

Badalona, Barcelona, Córdoba, Galdakao, Granollers, Hospitalet Llobregat, L'Hospitalet de Llobregat, Madrid

2026-09-17

Recruiting

A Study of BMS-986528 in Participants With Refractory Rheumatoid Arthritis

NCT07412704Arthritis, Rheumatoid

Bristol-Myers Squibb

Phase 1/2

A Coruña, Córdoba

2026-09-15

Not yet open

eHealth Lifestyle Intervention To Enhance Outcomes in HFpEF

NCT07661732Heart Failure and Preserved Ejection Fraction, Obesity & Overweight, Heart Failure

Maimónides Biomedical Research Institute of Córdoba

Not applicable

Córdoba

2026-09-01

Recruiting

A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)

NCT07624305Renal Insufficiency, Chronic

DrugsBalcinrenone/dapagliflozin·Dapagliflozin

AstraZeneca

Phase 3

2,800

Badajoz, Barcelona, Córdoba, Girona, Madrid, Majadahonda, Talavera de la Reina, Valencia

2026-09-01

Recruiting

A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.

NCT07753993Chronic Kidney Disease

DrugElecoglipron

AstraZeneca

Phase 3

7,000

Badajoz, Barcelona, Burgos, Córdoba, Granada, Madrid, Majadahonda, Málaga

2026-08-21

Recruiting

Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/Refractory Hematologic Autoimmune Disease

NCT07549698Warm Autoimmune Hemolytic Anemia (WAIHA), ITP - Immune Thrombocytopenia, Warm Autoimmune Hemolytic Anemia, Immune Thrombocytopenic Purpura

DrugZugo-cel

CRISPR Therapeutics AG

Phase 1/2

Córdoba, Madrid, Seville

2026-07-17

Recruiting

A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed

NCT07650916HIV Infections

DrugsCab Ula·Rpv La·Cabotegravir

ViiV Healthcare

Phase 3

564

Pozuelo de Alarcón, Alicante, Badalona, Barcelona, Burgos, Cartagena Murcia, Córdoba, Elche Alicante

2026-06-25

Recruiting

Oral Decitabine Plus Ivosidenib as First Line for Older/Unfit Adult AML Patients

NCT07507760Acute Myeloid Leukemia With Gene Mutations

DrugsDecitabine/Cedazuridine·Hydroxyurea·Ivosidenib·Cytarabine

PETHEMA Foundation

Phase 2

Albacete, Alicante, Burgos, Cáceres, Córdoba, Las Palmas, Las Palmas de Gran Canaria, Lugo

2026-06-12

Recruiting

Study to Evaluate the Efficacy and Safety of Atezolizumab and Bevacizumab as Neoadjuvant Plus Adjuvant Treatment in HCC

NCT07018947Resectable Hepatocellular Carcinoma

DrugAtezolizumab and Bevacizumab

Fundacion Clinic per a la Recerca Biomédica

Phase 2

Badalona, Barcelona, Santander, Córdoba, Girona, Madrid, Puerto de la Torre, Valencia

2026-06-02

Recruiting

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

NCT07192952Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric)

DrugFinerenone

Bayer

Phase 3

117

Esplugues de Llobregat, Barcelona, Córdoba, Madrid, Málaga, Seville

2026-06-01

Recruiting

A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk

NCT07613294Atherosclerosis, Cardiovascular Diseases, Lipoprotein(a)

DrugLepodisiran

Eli Lilly and Company

Phase 3

252

A Coruña, Barcelona, Córdoba, Las Palmas de Gran Canaria, Madrid, Seville, Valencia

2026-06-01

Not yet open

Adjuvant Clopidogrel in Staphylococcus Aureus Bacteremia

NCT07384702Bacteremia Due to Staphylococcus Aureus

DrugClopidogrel

Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Phase 2

230

Alicante, Barcelona, Córdoba, Granada, Jerez de la Frontera, Madrid, Palma de Mallorca, Seville

2026-06

Not yet open

Pembrolizumab Plus Belzutifan With or Without Lenvatinib in Localized Renal Cell Carcinoma

NCT07593040Renal Cell Carcinoma

DrugsLenvatinb·Belzutifan

Vall d'Hebron Institute of Oncology

Phase 2

150

Córdoba, Zaragoza, Santander, Barcelona, L'Hospitalet de Llobregat, Sabadell, Lugo, Ourense

2026-06

Not yet open

Effects of 8-Week CrossFit-Based Concurrent Training on Fitness, Body Composition, and Psychological Outcomes in Schoolchildren

NCT07552844Children, Crossfit, Psychology, Child, Physical Fitness

Maimónides Biomedical Research Institute of Córdoba

Not applicable

Córdoba

2026-06

Recruiting

A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

NCT07518186Multiple Myeloma

DrugsRamantamig·Teclistamab

Janssen Research & Development, LLC

Phase 3

700

Barcelona, Cáceres, Córdoba, Jerez de la Frontera, Madrid, Pamplona, Salamanca, Santander

2026-05-31

Recruiting

Efficacy of the Use of Neoadjuvant With/Without Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Locally Advanced Colon Cancer

NCT06783491Locally Advanced Colorectal Cancer

DrugsMitomycin C·Folfox

Maimónides Biomedical Research Institute of Córdoba

Phase 3

1,083

Córdoba

2026-05-26

Recruiting

Efficacy of Faricimab in Patients With Subretinal Hyper-reflective Material

NCT07403825Macular Degeneration, Age Related

DrugsVabysmo·Faricimab

Biobizkaia Health Research Institute

Phase 4

100

Córdoba, Bilbao, Valladolid, Albacete, Barcelona, Madrid, Majadahonda, Oviedo

2026-05-25

Recruiting

A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer

NCT07525206Colorectal Cancer

DrugsTelisotuzumab Adizutecan·Trifluridine/Tipiracil·Bevacizumab

AbbVie

Phase 3

990

Barcelona, Córdoba, Madrid, Valencia, Zaragoza

2026-05-22

Recruiting

A Study to Assess How Well and Safely Elafibranor Works in Adult Participants With Primary Sclerosing Cholangitis

NCT07387549Primary Sclerosing Cholangitis

DrugElafibranor

Ipsen

Phase 3

350

Barcelona, Córdoba, Madrid, Pontevedra, Santander, Valencia, Zaragoza

2026-05-14

Recruiting

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

NCT07549412Metastatic Colorectal Cancer

DrugsTrifluridine/Tipiracil·Bevacizumab

EMD Serono Research & Development Institute, Inc.

Phase 3

1,020

Córdoba, Barcelona, Madrid, Seville

2026-05-06

Recruiting

Ultra-brief Psychological Treatments for Emotional Symptoms and Disorders

NCT06909669Depression - Major Depressive Disorder, Generalized Anxiety Disorder, Generalized Anxiety, Anxiety

Universidad de Córdoba

Not applicable

184

Córdoba

2026-04-28

Recruiting

EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

NCT07287670Diffuse Cutaneous Systemic Sclerosis

Mediar Therapeutics

Phase 2

Barcelona, Córdoba, Málaga, Valencia

2026-04-16

Recruiting

Remibrutinib Open Label Roll-over Post-trial Access Protocol

NCT07456891Indication of the Parent Protocol

DrugRemibrutinib

Novartis Pharmaceuticals

Phase 3

648

Barcelona, Alicante, Córdoba, Madrid, Valencia

2026-04-16

Recruiting

A Study to Evaluate the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia (ExCIT)

NCT07286032Patients With Chemotherapy-Induced Thrombocytopenia

DrugHetrombopag Olamine

Jiangsu HengRui Medicine Co., Ltd.

Phase 3

150

Barcelona, Córdoba, Lleida, Madrid, Ourense, Sant Cugat del Vallès

2026-04-16

Recruiting

A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM)

NCT07227311Multiple Myeloma

DrugsBelantamab mafodotin·Velcade·Carfilzomib·Pomalidomide

GlaxoSmithKline

Phase 2

200

Jerez de la Frontera, Badalona, Córdoba, Gijón, Madrid, Málaga, Salamanca, Vitoria-Gasteiz

2026-04-15

Recruiting

A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus

NCT07430306Systemic Lupus Erythematosus

DrugAnifrolumab

AstraZeneca

Phase 3

245

Barcelona, Córdoba, Galdakao, Madrid, Sabadell, Santander, Seville, Valencia

2026-04-13

Recruiting

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)

NCT07355218Systematic Lupus Erythematosus, Cutaneous Lupus Erythematosus

DrugEnpatoran

EMD Serono Research & Development Institute, Inc.

Phase 3

202

Valladolid, CastellÃ³n, Córdoba, Madrid

2026-04-01

Recruiting

Recovery After Fatigue in Young Athletes: Comparison Between TECAR Therapy and Cycle Ergometer"

NCT07547566Muscle Fatigue, Healthy Adult

Maimónides Biomedical Research Institute of Córdoba

Not applicable

Córdoba

2026-04

Recruiting

A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer

NCT07287150Metastatic Castration-Resistant Prostate Cancer

DrugsInavolisib·Abiraterone·Enzalutamide·Docetaxel

Hoffmann-La Roche

Phase 2

100

Barakaldo, Córdoba, Madrid, Valencia

2026-03-11

Recruiting

Study on Prostate Salvage Using High-dose-rate Brachytherapy

NCT07860528Prostate Cancer, Locally Recurrent Cancer, Biochemically Recurrent Prostate Carcinoma, Toxicity Radiation

Instituto de Investigación en Oncología Radioterápica - Fundación Española de Oncología Radioterápic

Observational

Benidorm, L'Hospitalet de Llobregat, Santander, Córdoba, San Sebastián, Madrid, Pamplona, Vigo

2026-03-11

Recruiting

A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

NCT07441642Geographic Atrophy Secondary to Age-related Macular Degeneration

Novartis Pharmaceuticals

Phase 2

272

Santiago Compostela, Sant Cugat Del V, Burjassot, Córdoba

2026-03-09

Recruiting

A Phase IIb Dose-ranging Study to Assess the Efficacy and Safety of GIA632 in Participants With Non-segmental Vitiligo

NCT07431177Non-segmental Vitiligo

DrugGIA632

Novartis Pharmaceuticals

Phase 2

210

Santiago de Compostela, Barcelona, Córdoba, Madrid, Pontevedra, Seville

2026-03-09

Not yet open

Effects of HMB and Rehabilitation Program in Athletes With Patellar Tendinopathy

NCT07466407Patellar Tendinopathy

Universidad Complutense de Madrid

Not applicable

Córdoba

2026-03-01

Not yet open

Radiofrequency Ablation Multicenter Observational Study in Renal Oncology Patients

NCT07465458Renal Carcinoma

Humanitas Hospital, Italy

Observational

226

Barcelona, Córdoba, Madrid, San Sebastián

2026-03

Recruiting

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

NCT07318558Ovarian Neoplasms, Ovarian Cancer

DrugsMvasi·Sacituzumab tirumotecan·Avastin·Bevacizumab

Merck Sharp & Dohme LLC

Phase 3

900

Girona, A Coruña, Madrid, Valencia, Barcelona, Córdoba

2026-02-16

Recruiting

ReDS-guided Decongestion Strategy in Patients Hospitalized for Heart Failure

NCT07484009Acute Heart Failure (AHF), Heart Failure (for Example, Fluid Overload), Heart Failure Hospitalization

Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal

Not applicable

1,014

Madrid, Barcelona, Córdoba, Girona, Málaga, Murcia, Salamanca, Sant Joan Despí

2026-01-29

Active, closed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7812653 in Participants With Early Symptomatic Alzheimer's Disease (eAD)

NCT07234942Alzheimer's Disease

Hoffmann-La Roche

Phase 1

Sant Cugat del Vallès, Barcelona, Córdoba

2026-01-27

Recruiting

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

NCT07216703Cervical Cancer

DrugsMvasi·Sacituzumab tirumotecan·Paraplatin·Avastin

Merck Sharp & Dohme LLC

Phase 3

1,023

Girona, Valencia, Barcelona, Córdoba, Madrid

2026-01-19

Recruiting

A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

NCT07195682Renal Cell Carcinoma

DrugsPumitamig·Yervoy·Ipilimumab

Bristol-Myers Squibb

Phase 1

281

Córdoba, Barcelona

2026-01-15

Recruiting

A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis

NCT07223697Atopic Dermatitis

DrugAfimkibart

Hoffmann-La Roche

Phase 2

120

Pamplona, Córdoba

2026-01-08

Not yet open

Evaluation of Safety, Tolerability and Preliminary Efficacy of Etrinabdione in Patients With Peripheral Arterial Disease

NCT06774040Peripheral Arterial Disease

VivaCell Biotechnology España

Phase 2

Córdoba

2026-01-01

Not yet open

Efficacy of Non-invasive Neuromodulation Treatments for COVID-19 Sequelae

NCT06544395Covid-19 Recurrent

Clinica Gema Leon

Not applicable

104

Córdoba

2026-01-01

Recruiting

AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer

NCT07218809Epithelial Ovarian Cancer

DrugsTorvutatug samrotecan·MIRV·Mirvetuximab Soravtansine·Pegylated liposomal doxorubicin

AstraZeneca

Phase 3

1,100

A Coruña, Badalona, Barcelona, Córdoba, Donostia / San Sebastian, Girona, L'Hospitalet de Llobregat, Madrid

2025-12-29

Recruiting

A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis Suppurativa

NCT07225569Hidradenitis Suppurativa

Sanofi

Phase 2

144

Bilbao, Barcelona, Seville, Córdoba, Málaga

2025-12-29

Recruiting

INFLATE Study: Investigation of the Safety and Performance of a Novel PTV Balloon in Patients Undergoing TAVI for Severe Aortic Stenosis

NCT06816485Aortic Diseases

Biosensors Europe SA

Not applicable

Barcelona, Córdoba, Huelva, Madrid, Seville, Valencia, Valladolid

2025-12-15

Recruiting

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

NCT07218380Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Neoplasm Metastasis

DrugsVepugratinib·Pembrolizumab

Eli Lilly and Company

Phase 3

450

Badajoz, Badalona, Barakaldo, Barcelona, Córdoba, Elche, Girona, Hospitalet

2025-12-12

Recruiting

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

NCT07222800Intestinal Neoplasms, Gastrointestinal Neoplasms, Digestive System Neoplasms, Neoplasms by Site

DrugsPF-08634404·Avastin·Bevacizumab

Pfizer

Phase 3

800

Santiago de Compostela, Málaga, Barcelona, L'Hospitalet de Llobregat, Jerez de la Frontera, Madrid, Córdoba, Valencia

2025-12-11

Recruiting

A Study of Clinical Outcomes in Participants With EGFR Mutated Advanced Non-Small Cell Lung Cancer (NSCLC) in a Real-World Setting

NCT07230691Carcinoma, Non-Small-Cell Lung

Janssen Research & Development, LLC

Observational

380

Córdoba, Jerez de la Frontera, Lugo, Málaga, Ourense, Palma de Mallorca, Santiago de Compostela, Seville

2025-12-03

Recruiting

Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

NCT07201558Rheumatoid Arthritis, Systemic Lupus Erythematosus

DrugSurovatamig

AstraZeneca

Phase 1

Barcelona, Córdoba, Madrid

2025-12-02

Recruiting

An Efficacy and Safety Study of DFL24498 in the Treatment of AKC

NCT07395232Atopic Keratoconjunctivitis

DrugDFL24498

Dompé Farmaceutici S.p.A

Phase 3

153

Córdoba, Santiago de Compostela, Valencia, Valladolid, Zaragoza

2025-12-01

Not yet open

Impact of CMV-Specific Immune Reconstitution at the End of Letermovir Prophylaxis on the Development of Late Cytomegalovirus Infection in Hematopoietic Stem Cell Transplant Recipients (INMUNOEND)

NCT06814301Cytomegalovirus Cell Mediated Immunity, Stem Cell Transplantation, Hematopoietic

Maimónides Biomedical Research Institute of Córdoba

Observational

123

Córdoba

2025-12-01

Recruiting

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

NCT07227402Renal Cell Carcinoma

DrugsZanzalintinib·Belzutifan·Cabozantinib

Merck Sharp & Dohme LLC

Phase 3

904

L'Hospitalet de Llobregat, Santander, Girona, Madrid, Valencia, Barcelona, Córdoba

2025-11-26

Recruiting

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

NCT07188805Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric)

DrugFinerenone

Bayer

Phase 3

111

Esplugues de Llobregat, Barcelona, Córdoba, Madrid, Málaga, Seville

2025-11-19

Recruiting

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

NCT07228832Metastatic Colorectal Cancer (CRC)

DrugsIvonescimab·Leucovorin·Adrucil·Oxaliplatin

Summit Therapeutics

Phase 3

600

A Coruña, Barcelona, Córdoba, Granada, Madrid, Málaga, Palma de Mallorca, Santander

2025-11-18

Recruiting

A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

NCT06948448Colorectal Cancer

DrugsONO-4578·Leucovorin·Opdivo·Adrucil

Ono Pharmaceutical Co., Ltd.

Phase 2

144

Badalona, Barcelona, Córdoba, Madrid, Seville, Málaga, Valencia

2025-11-18

Recruiting

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

NCT07023627Ovarian Cancer

DrugINCB123667

Incyte Corporation

Phase 2

160

Barcelona, Córdoba, Girona, Madrid, Murcia, Valencia

2025-11-12

Recruiting

Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

NCT07007065Neovascular Age-related Macular Degeneration

DrugSurabgene Lomparvovec

AbbVie

Phase 3

561

Córdoba, Donostia / San Sebastian, Majadahonda, Asturias, Seville, Barcelona, Madrid, Valencia

2025-11-05

Recruiting

Levothyroxine as Adjuvant to a Hypocaloric Diet for the Treatment of Obesity.

NCT07332273Obesity

DrugLevothyroxine

Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud

Phase 3

286

Cadiz, Córdoba, Jaén, Málaga, Valladolid

2025-11-05

Recruiting

A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation

NCT06243731Cytomegalovirus (CMV), Kidney Disease, Kidney Failure

Takeda

Observational

L'Hospitalet de Llobregat, Barakaldo, Barcelona, Córdoba, Madrid, Málaga, Seville

2025-11-03

Recruiting

A Study of Zasocitinib in Adults With Nonsegmental Vitiligo

NCT07108283Nonsegmental Vitiligo

DrugZasocitinib

Takeda

Phase 2

200

Las Palmas de Gran Canaria, Córdoba, Madrid, Valencia

2025-11-03

Recruiting

Digital Health Education to Improve Cardiovascular Health Across Different Socioeconomic Groups: e-DUCASS Advance

NCT07835386Cardiovascular Health, Health Literacy

Maimónides Biomedical Research Institute of Córdoba

Not applicable

600

Córdoba

2025-11-01

Recruiting

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

NCT07173751Breast Neoplasms

DrugsEribulin·Pumitamig·Gemcitabine·Carboplatin

BioNTech SE

Phase 3

558

Badajoz, Barcelona, Córdoba, Madrid, Murcia, Pamplona, Sabadell, Valencia

2025-10-30

Recruiting

A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.

NCT07219615Chronic Spontaneous Urticaria

DrugsLitfulo·Ritlecitinib

Pfizer

Phase 2

200

Santiago de Compostela, Córdoba, Barcelona, Alcorcón, Valencia

2025-10-30

Recruiting

Study to Evaluate Efficacy and Safety of ONL1204 in Patients With GA Associated With AMD

NCT06659445Geographic Atrophy (GA), Age - Related Macular Degeneration (AMD)

DrugAvacincaptad Pegol

ONL Therapeutics

Phase 2

324

Barcelona, Bilbao, Córdoba, Madrid, Seville, Valencia, Zaragoza

2025-10-28

Recruiting

Trial of Orbital Atherectomy Versus Standard Strategy in Calcified Bifurcation Lesions

NCT06736899Coronary Artery Disease, Coronary Disease

Fundación EPIC

Not applicable

200

Alicante, Barcelona, Córdoba, Fuencarral-El Pardo, Lugo, Madrid, Salamanca, Seville

2025-10-23

Recruiting

A Non-interventional Study of Participants With BPDCN Treated With Chemotherapy

NCT07785180Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Stemline Therapeutics, Inc.

Observational

140

Albacete, Alicante, Badalona, Burgos, Cáceres, Córdoba, Madrid, Oviedo

2025-10-17

Recruiting

CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

NCT07207811Transthyretin Amyloid Cardiomyopathy (ATTR CM)

DrugNNC6019-0001

Novo Nordisk A/S

Phase 3

1,280

A Coruña, Badalona, Barcelona, Bilbao, Córdoba, Donostia / San Sebastian, L'Hospitalet de Llobregat, Las Palmas de Gran Canaria

2025-10-02

Recruiting

Continuation of Cetuximab Beyond First-Line Progression in Metastatic Colorectal Cancer

NCT07389265Metastatic Colorectal Cancer (mCRC)

DrugsFOLFOX (Folinic acid·Erbitux·Folfox·Fluorouracil

University of Campania Luigi Vanvitelli

Phase 3

480

Barcelona, Cartagena, Córdoba, Granada, L'Hospitalet de Llobregat, Madrid, Málaga, Pamplona

2025-10-01

Recruiting

Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)

NCT07204275Primary Membranous Nephropathy

DrugsPovetacicept·Tacrolimus

Vertex Pharmaceuticals Incorporated

Phase 2/3

176

Barcelona, Córdoba, Elche, Lugo, Pamplona, Seville

2025-09-30

Recruiting

Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy

NCT07106762Urothelial Cancer

DrugsIza-bren·Gemcitabine·Cisplatin·Carboplatin

Bristol-Myers Squibb

Phase 2/3

470

Barcelona, Santander, Madrid, Valencia, Badajoz, Córdoba, Seville

2025-09-30

Recruiting

A Study Evaluating the Effects of Filgotinib in Children and Teenagers With Ulcerative Colitis

NCT06865417Ulcerative Colitis

DrugFilgotinib

Alfasigma S.p.A.

Phase 3

Badalona, Córdoba

2025-09-29

Recruiting

A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

NCT07111520Non-small Cell Lung Cancer

DrugsBNT326·Pumitamig

BioNTech SE

Phase 1/2

880

Barcelona, Córdoba, Madrid, Málaga, Pamplona, Seville, Valencia

2025-09-22

Active, closed

A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

NCT07169578Alzheimers Disease

DrugTrontinemab

Hoffmann-La Roche

Phase 3

1,101

Sant Cugat del Vallès, Terrassa, Donostia / San Sebastian, Lleida, Pozuelo de Alarcón, Barcelona, Córdoba, Madrid

2025-09-17

Active, closed

A Study to Test Whether Nerandomilast Helps People With Lung Fibrosis Related to Rheumatic Diseases

NCT06806592Interstitial Lung Diseases, Systemic Autoimmune Rheumatic Diseases Associated Interstitial Lung Diseases

DrugNerandomilast

Boehringer Ingelheim

Phase 3

413

Barcelona, Bilbao, Córdoba, Huelva, L'Hospitalet de Llobregat, Madrid, Santiago de Compostela, Seville

2025-09-13

Recruiting

Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

NCT07011719Metastatic Clear Cell Renal Cell Carcinoma, Advanced Clear Cell Renal Cell Carcinoma

DrugsCasdatifan·Cabozantinib

Arcus Biosciences, Inc.

Phase 3

720

Barcelona, Córdoba, Madrid, Majadahonda, Málaga, Pamplona, Santander, Seville

2025-09-08

Recruiting

Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

NCT07157774Elevated Lp(a), Atherosclerotic Cardiovascular Disease (ASCVD)

Eli Lilly and Company

Phase 3

10,450

A Coruña, Barcelona, Centelles, Córdoba, Ferrol, Granada, Huelva, Jaén

2025-09-02

Not yet open

5-fluorouracil Plus Panitumumab (Anti-EGFR) and Sotorasib (KRAS G12C Inhibitor) in First-line Treatment of Patients Non-eligible for a Doublet/Triplet Chemotherapy With Advanced Unresectab

NCT07124884Colorectal Carcinoma, KRAS G12C Mutation, Unresectable Colorectal Cancer

Federation Francophone de Cancerologie Digestive

Phase 2

300

Barcelona, Córdoba, L'Hospitalet de Llobregat, Madrid, Oviedo, Pamplona, Salamanca, San Carlos

2025-08-31

Recruiting

A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors

NCT07169734Cervical Squamous Cell Carcinoma, Squamous Non-small-cell Lung Cancer, Colorectal Cancer, Intrahepatic Cholangiocarcinoma

Alentis Therapeutics AG

Phase 1/2

180

Barcelona, Córdoba, El Palmar, Madrid, Seville, Tarragona, Valencia

2025-08-26

Not yet open

Home-based Empowerment Through Physical Exercise Assisted by Technology for Frail Patients

NCT07118761Frailty

University Hospital of Ferrara

Not applicable

120

Córdoba

2025-08-15

Recruiting

Focused Orticumab Research for Treating Inflammation in Coronary Arteries

NCT06927739Acute Coronary Syndromes, Coronary Arterial Disease (CAD), Inflammation, Heart Disease

Abcentra

Phase 2

240

Córdoba, Madrid, El Palmar, Seville

2025-08-11

Recruiting

Sotorasib Combined With First-line Chemotherapy for Advanced Pancreatic Adenocarcinoma

NCT06892054Pancreatic Adenocarcinoma

DrugSotorasib

Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)

Phase 1

Zaragoza, Barcelona, Santander, Córdoba, Donostia / San Sebastian, Madrid, Málaga, Pamplona

2025-08-08

Recruiting

Evaluation of Safety and Effectiveness of an IOL With a Virtual Aperture Optic

NCT05955846Intraocular Lens, Cataract, Presbyopia

Z Optics, Inc.

Not applicable

Alicante, Ceuta, Córdoba, Madrid, Palma de Mallorca

2025-08-07

Active, closed

A Study Evaluating Persistence of the Immune Response of the Adjuvanted Respiratory Syncytial Virus (RSV) Vaccine and the Safety and Immune Response Following Revaccination in Adults 18 Years of Age and Above Who Received Lung or Kidney Transplant

NCT07092865Respiratory Syncytial Virus Infections

GlaxoSmithKline

Phase 2

168

A Coruña, Barcelona, Córdoba, Madrid, Santander

2025-08-06

Recruiting

A Phase 3 Single-arm Study of UGN-104 for the Treatment of Low-grade Upper Tract Urothelial Cancer

NCT06774131Upper Urinary Tract Urothelial Carcinoma, Urothelial Carcinoma

UroGen Pharma Ltd.

Phase 3

Barcelona, A Coruña, Madrid, Cadiz, Córdoba, Murcia, Seville, Valencia

2025-08-06

Recruiting

Phase 1b/2a Clinical Trial to Determine the Safety, Tolerability and Efficacy of TZ-161 in Spinal Cord Injury

NCT06677229Acute Spinal Cord Injury (SCI)

Technophage, SA

Phase 1/2

Córdoba, Madrid

2025-08-01

Recruiting

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

NCT07044336Endometrial Cancer, Malignant Solid Tumour

DrugsAdriamycin·Taxol·Doxorubicin·Paclitaxel

AstraZeneca

Phase 3

800

Badalona, Barcelona, Córdoba, El Palmar (Murcia), L'Hospitalet de Llobregat, Madrid, Málaga, Oviedo

2025-08-01

Recruiting

EAST-1 (ERAP-inhibition in Axial Spondyloarthritis Trial - 1)

NCT07047703Axial Spondyloarthritis (AxSpA)

Grey Wolf Therapeutics

Phase 1/2

140

Madrid, Córdoba, Sabadell

2025-07-28

Recruiting

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

NCT07037433Atherosclerotic Cardiovascular Disease, Overweight, Obesity

DrugMaridebart cafraglutide

Amgen

Phase 3

12,800

Castilleja de la Cuesta, Córdoba, Jaén, Málaga, Seville, San Cristóbal de La Laguna, Santander, Badalona

2025-07-25

Recruiting

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

NCT07064473Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases

DrugsVicadrostat·Dapagliflozin

Boehringer Ingelheim

Phase 3

11,800

Badalona, Barcelona, Beiro, Córdoba, Galdakao, Huelva, Jaén, Las Palmas de Gran Canaria

2025-07-22

Active, closed

A Study Evaluating BFB759 in Moderate to Severe Atopic Dermatitis

NCT07105488Atopic Dermatitis (AD)

DrugBFB759

Bluefin Biomedicine, Inc.

Phase 2

225

Alicante, Córdoba, Granollers, Madrid

2025-07-15

Recruiting

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

NCT07013474COVID-19 Infection

DrugsIbuzatrelvir·Veklury·Remdesivir

Pfizer

Phase 3

300

A Coruña, Córdoba, Badalona, Barcelona, Madrid, Vigo, Alicante, Seville

2025-07-14

Active, closed

A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV

NCT07053384HIV Infections

DrugsVH3810109·Fostemsavir

ViiV Healthcare

Phase 1

107

Pozuelo de Alarcón, Barcelona, Córdoba, La Laguna Santa Cruz, Madrid, Palma de Mallorca, Seville, Valencia

2025-07-10

Active, closed

An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

NCT06991556Metastatic Hormone-sensitive Prostate Cancer

DrugsLuxdegalutamide·Abiraterone·Enzalutamide

Novartis Pharmaceuticals

Phase 2

168

Santander, Badajoz, Lugo, Barcelona, Córdoba

2025-07-07

Recruiting

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

NCT07177352Alzheimers Disease

Hoffmann-La Roche

Phase 3

80,000

Denia, Martorell, Terrassa, Pozuelo de Alarcón, Barcelona, Córdoba, Donosti-San Sebastián, Granada

2025-07-02

Active, closed

Efficacy and Safety of IMVT-1402 in Adult Participants With Primary Sjogren's Disease With Moderate to Severe Systemic Disease Activity

NCT06979531Primary Sjögren's Syndrome

DrugIMVT-1402

Immunovant Sciences GmbH

Phase 2

180

Bilbao, Cadiz, Córdoba, Mérida, Valencia

2025-06-30

By invitation

A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Moderate to Severe Hidradenitis Suppurativa

NCT07007637Hidradenitis Suppurativa

DrugSonelokimab

MoonLake Immunotherapeutics AG

Phase 3

835

Alicante, Badalona, Barcelona, Cadiz, Córdoba, Granada, Granollers, Madrid

2025-06-27

Recruiting

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

NCT07037459Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction, Obesity

DrugMaridebart cafraglutide

Amgen

Phase 3

5,056

Córdoba, Málaga, Las Palmas de Gran Canaria, Badalona, Barcelona, L'Hospitalet de Llobregat, Lleida, A Coruña

2025-06-25

Recruiting

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

NCT06846281Relapsing Multiple Sclerosis

DrugsRemibrutinib·Ocrelizumab

Novartis Pharmaceuticals

Phase 3

400

El Palmar, Valencia, Barcelona, Córdoba, Madrid, Málaga, Seville

2025-06-23

Recruiting

A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

NCT06972446Rheumatoid Arthritis

DrugsABBV-8736·ABBV-701·Lutikizumab·Adalimumab

AbbVie

Phase 2

180

Sabadell, Seville, Bilbao, A Coruña, Córdoba, Madrid, Valencia

2025-06-20

Active, closed

A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)

NCT07037771Homozygous Familial Hypercholesterolemia

DrugZodasiran

Arrowhead Pharmaceuticals

Phase 3

Barcelona, Córdoba, Madrid

2025-06-17

Recruiting

Orbital Atherectomy vs Intravascular Lithotripsy for the Treatment of Calcified Coronary Nodules (ORBIT-SHOCK).

NCT06736665Coronary Arterial Disease (CAD), Coronary Calcification, Coronary Calcified Nodules, Orbital Atherectomy

Spanish Society of Cardiology

Not applicable

Alicante, Lugo, Madrid, Salamanca, Valladolid, Córdoba

2025-06-12

Recruiting

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

NCT06340568Endometrial Cancer

DrugsDoxorubicin·Docetaxel·Paclitaxel

BioNTech SE

Phase 3

480

Barcelona, Córdoba, Donostia / San Sebastian, Girona, Madrid, Valencia

2025-06-10

Active, closed

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With HeFH

NCT07000136Heterozygous Familial Hypercholesterolaemia

DrugAZD0780

AstraZeneca

Phase 3

473

A Coruña, Barcelona, Córdoba, Reus, Seville

2025-06-10

Recruiting

Post-Market Celect Platinum Vena Cava Filter and Gunther Tulip Retrieval Set Study

NCT05881798Deep Vein Thrombosis, Venous Thromboembolism, Pulmonary Embolism

Cook Research Incorporated

Observational

Barcelona, Córdoba, Sabadell

2025-06-02

Active, closed

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

NCT07000123Cardiovascular Disease

DrugAZD0780

AstraZeneca

Phase 3

3,103

A Coruña, Barcelona, Córdoba, Madrid, Santiago(A Coruña), Seville

2025-05-28

Recruiting

Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis

NCT07039916Generalized Myasthenia Gravis

DrugIMVT-1402

Immunovant Sciences GmbH

Phase 3

231

Barcelona, Córdoba, Madrid

2025-05-27

Recruiting

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

NCT06952504Endometrial Cancer

DrugsSacituzumab tirumotecan·Docetaxel·Keytruda·Paclitaxel

Merck Sharp & Dohme LLC

Phase 3

1,123

L'Hospitalet de Llobregat, Girona, Barcelona, Córdoba, Madrid, Valencia

2025-05-22

Recruiting

Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation

NCT06830798Delayed Graft Function, DGF, Kidney Transplant

DrugRavulizumab

Alexion Pharmaceuticals, Inc.

Phase 3

450

Badajoz, Barakaldo, Barcelona, Cadiz, Córdoba, Granada, Madrid, Málaga

2025-05-19

Active, closed

Tibulizumab Skin Healing and Inflammation Evaluation for Lasting Defense

NCT06993610Hidradenitis Suppurativa (HS)

Zura Bio Inc

Phase 2

225

Córdoba, Madrid, Zaragoza

2025-05-16

Not yet open

Biomarkers in EV Associated With Marrow Adiposity in Anorexia

NCT06712485Anorexia Nervosa Restricting Type, Anorexia Nervosa (DSM-IV Revised Criteria)

Maimónides Biomedical Research Institute of Córdoba

Observational

Córdoba

2025-05-15

Recruiting

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

NCT06925737Prostate Cancer, Prostatic Neoplasms

DrugsIfinatamab Deruxtecan·Prednisolone·Prednisone·Docetaxel

Merck Sharp & Dohme LLC

Phase 3

1,440

Santander, Santiago de Compostela, Majadahonda Madrid, Madrid, Barcelona, Córdoba, Lugo, Seville

2025-05-13

Recruiting

A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

NCT06892548Advanced Lung Cancer

DrugsBNT324·Pumitamig

BioNTech SE

Phase 1/2

594

Barcelona, Córdoba, Málaga, Seville, Torrejón de Ardoz, Valencia

2025-05-02

Active, closed

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

NCT06813911Atherosclerotic Cardiovascular Disease (ASCVD)

DrugsPelacarsen·Inclisiran

Novartis Pharmaceuticals

Phase 3

246

Santiago Compostela, Pamplona, Castilleja de la Cuesta, A Coruña, Barcelona, Córdoba, Huelva, Las Palmas GC

2025-04-30

Recruiting

Drug-Drug Intercations and Direct Acting Antiviral Agents Against HCV

NCT06928259HCV Infection

University of Seville

Observational

728

Cadiz, Córdoba, Huelva, Seville

2025-04-30

Recruiting

Optimising TREATment for Severe Gram-Negative Bacterial Infections

NCT07004049Bloodstream Infection, Ventilator Associated Bacterial Pneumonia, Hospital Acquired Bacterial Pneumonia, Carbapenem Resistant Bacterial Infection

DrugsCeftolozane-tazobactam·Cefiderocol·Fosfomycin·Meropenem-Vaborbactam

National University of Singapore

Phase 4

600

Alicante, Badajoz, Barakaldo, Barcelona, Córdoba, Granada, Madrid, Málaga

2025-04-21

Recruiting

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

NCT06824467Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer

DrugsSteroid mouthwash (dexamethasone·Mvasi·Acetaminophen·Sacituzumab tirumotecan

Merck Sharp & Dohme LLC

Phase 3

770

Girona, Madrid, Valencia, Barcelona, Córdoba

2025-04-09

Active, closed

A Study to Assess the Efficacy and Safety of Afimkibart (RO7790121) in Participants With Moderate to Severe Atopic Dermatitis

NCT06863961Atopic Dermatitis

DrugAfimkibart

Hoffmann-La Roche

Phase 2

162

Santiago de Compostela, Pamplona, Córdoba, Madrid

2025-04-01

Recruiting

A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia Areata

NCT06873945Alopecia Areata

DrugsLitfulo·Ritlecitinib

Pfizer

Phase 3

674

Santiago de Compostela, Córdoba, Madrid, Zaragoza

2025-04-01

Recruiting

Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma

NCT06830759Diffuse Large B-cell Lymphoma, Follicular Lymphoma

AbbVie

Observational

700

A Coruña, Badalona, Sabadell, Córdoba, Marbella, Pamplona, Seville, Manises

2025-03-28

Recruiting

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

NCT06989112Endometrial Cancer

DrugsRilvegostomig·Taxotere·Paraplatin·Trastuzumab deruxtecan

AstraZeneca

Phase 3

600

A Coruña, Córdoba, Donostia / San Sebastian, El Palmar, L'Hospitalet de Llobregat, Madrid, Palma de Mallorca, Valencia

2025-03-27

Active, closed

Study of Eftilagimod Alfa (Efti) in Combination With Pembrolizumab and Chemotherapy Versus Placebo in Combination With Pembrolizumab and Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (TACTI-004)

NCT06726265Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

DrugsEfti·Pemetrexed·Keytruda·Paclitaxel

Immutep S.A.S.

Phase 3

756

Badalona, Barcelona, Córdoba, Madrid, Málaga, Oviedo, Sabadell, Seville

2025-03-21

Recruiting

Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)

NCT06797635Breast Neoplasms, Breast Cancer

DrugsPatritumab deruxtecan·Doxorubicin Hydrochloride·Epirubicin·Adriamycin

Merck Sharp & Dohme LLC

Phase 2

372

Badalona, Madrid, Córdoba

2025-03-20

Recruiting

Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

NCT06819007Ovarian Cancer

DrugsTrastuzumab deruxtecan·Bevacizumab

Daiichi Sankyo

Phase 3

582

A Coruña, Barcelona, Córdoba, El Palmar, Madrid, Palma, Pamplona, Planta Baja

2025-03-19

Recruiting

Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

NCT07032662Chronic Inflammatory Demyelinating Polyneuropathy

Immunovant Sciences GmbH

Phase 2

162

Barcelona, Bilbao, Córdoba, Santiago de Compostela, Valencia

2025-03-18

Recruiting

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

NCT06677060Heart Failure

DrugBaxdrostat/dapagliflozin

AstraZeneca

Phase 3

11,300

A Coruña, Barcelona, Córdoba, L'Hospitalet de Llobregat, Madrid, Málaga, Sant Joan Despí, Santiago(A Coruña)

2025-03-14

Active, closed

EucaLimus Post-Market Registry

NCT06621524Coronary Arterioscleroses

OrbusNeich

Observational

251

L'Hospitalet de Llobregat, Barcelona, Córdoba, Lugo, San Cristóbal de La Laguna, Tarragona

2025-03-14

Active, closed

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

NCT06764485Metastatic Castration-resistant Prostate Cancer

DrugsAbiraterone·Enzalutamide·Docetaxel

Celgene

Phase 3

960

Córdoba, Barcelona, Sabadell, Barakaldo, Santander, Lugo, Madrid, Majadahonda

2025-03-13

Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

NCT06925542SLE (Systemic Lupus), Lupus Erythematosus, Systemic, Lupus Nephritis, Systemic Sclerosis

DrugZugo-cel

CRISPR Therapeutics

Phase 1

Córdoba, Pamplona, Seville

2025-03-10

Recruiting

Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

NCT06855498Hidradenitis Suppurativa (HS)

DrugPovorcitinib

Incyte Corporation

Phase 3

600

Alcorcón, Alicante, Badalona, Barcelona, Córdoba, Granada, Las Palmas de Gran Canaria, Madrid

2025-02-28

Recruiting

Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

NCT06731478Gastric Cancer, Gastroesophageal Junction Cancer

DrugsTrastuzumab deruxtecan·Trastuzumab·Keytruda·Pembrolizumab

Daiichi Sankyo

Phase 3

726

Badalona, Barcelona, Córdoba, Elche, L'Hospitalet de Llobregat, Madrid, Málaga, Murcia

2025-02-27

Recruiting

A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)

NCT06747949Sjögren's Syndrome

DrugDazodalibep

Amgen

Phase 3

844

Santa Coloma de Gramenet, Córdoba, Bilbao, Madrid, Seville

2025-02-25

Active, closed

An Open-label Study to Assess the Safety, Efficacy, and Cellular Kinetics of YTB323 in Relapsing Multiple Sclerosis

NCT06617793Relapsing Multiple Sclerosis

DrugRapcabtagene autoleucel

Novartis Pharmaceuticals

Phase 1/2

Barcelona, Córdoba, Madrid, Valencia

2025-02-24

Active, closed

A Study to Evaluate the Efficacy and Safety of JNJ-77242113 (Icotrokinra) in Biologic-naïve Participants With Active Psoriatic Arthritis

NCT06878404Arthritis, Psoriatic

DrugIcotrokinra

Janssen Research & Development, LLC

Phase 3

552

A Coruña, Barcelona, Córdoba, Madrid, Málaga, Sabadell, Santander, Seville

2025-02-21

Active, closed

A Study of Bempedoic Acid in Combination With Ezetimibe and Either Rosuvastatin or Atorvastatin in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia

NCT06686615Primary Hypercholesterolemiia, Mixed Dyslipidemia

DrugsBempedoic acid·Ezetimibe·Rosuvastatin·Atorvastatin

Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Observational

2,000

Albacete, Alicante, Barakaldo, Burgos, Cadiz, Cantabria, Córdoba, Donostia / San Sebastian

2025-02-12

Active, closed

A Safety and Tolerability Study of VRDN-003 in Participants With Thyroid Eye Disease (TED)

NCT06812325Thyroid Eye Disease (TED)

DrugVRDN-003

Viridian Therapeutics, Inc.

Phase 3

320

A Coruña, Barcelona, Córdoba, Madrid, Navarrés, Seville, Zaragoza

2025-02-03

Recruiting

EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma

NCT06556563Glioblastoma

DrugsTemozolomide·Keytruda·Pembrolizumab

NovoCure GmbH

Phase 3

741

Madrid, Barcelona, Córdoba, Granada, Seville, Valencia

2025-02-03

Recruiting

Comparision of Hydrodilatation Results at Different Volumes in Adhesive Capsulitis by Phases.

NCT06939530Capsulitis of Shoulder, Hydrodilatation

Javier Muñoz Paz

Not applicable

Córdoba

2025-02-02

Recruiting

Study to Assess the Safety and Effectiveness of Beltaven® in Patients With Allergy to Apis Mellifera, Polistes Dominula or Vespula Spp.

NCT07309822Allergy

Probelte Pharma S.L.U.

Observational

Barcelona, Castellon, Ciudad Real, Córdoba, Girona, Lleida, Madrid, Orihuela

2025-02-01

Active, closed

Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)

NCT06710132Solid Tumors, Gastric Cancer, Non-Small Cell Lung Cancer (NSCLC), Pancreatic Cancer

DrugM9140

EMD Serono Research & Development Institute, Inc.

Phase 1/2

184

Córdoba, Badalona, Barcelona, L'Hospitalet de Llobregat, Madrid, Pozuelo de Alarcón, Seville, Valencia

2025-01-29

Recruiting

A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

NCT06807424Arthritis, Psoriatic

DrugIcotrokinra

Janssen Research & Development, LLC

Phase 3

750

A Coruña, Córdoba, L'Hospitalet de Llobregat, Madrid, Málaga, Santander, Santiago de Compostela, Seville

2025-01-09

Active, closed

A Phase IIIB Study to Evaluate the Use of Capivasertib in Combination With Fulvestrant in Patients With Advanced Breast Cancer Who Have Relapsed/Progressed on ET and CDK4/6 Inhibitor Reflecting Real World Clinical Practice in Spain

NCT06764186Locally Advanced or Metastatic Breast Cancer

DrugsCapivasertib·Fulvestrant

AstraZeneca

Phase 3

101

Alicante, Barcelona, Bilbao (Vizcaya), Córdoba, Donostia / San Sebastian, El Palmar, Girona, Madrid

2025-01-07

Recruiting

Development of a Predictive Model for Sexually Transmitted Infections in Individuals Using Pre-Exposure Prophylaxis for HIV in Spain

NCT06860945Sexually Transmitted Infections (STIs), HIV, PrEP

Hospital Universitario de Valme

Observational

9,000

Almería, Cadiz, Cartagena, Córdoba, Cuenca, Elche, Granada, Huelva

2025-01-01

Recruiting

Immunotherapy for the Treatment of Hymenoptera Venom Allergy in Real-life Conditions.

NCT06790368Allergy, Insect Venom, Allergy Insect Stinging, Insect Sting Allergy

DrugVenox

Inmunotek S.L.

Observational

Alcorcón, Córdoba, Guadalajara

2025-01-01

Active, closed

A Study to Evaluate the Use of Durvalumab in Combination With Platinum-based Chemotherapy Followed by Durvalumab With Olaparib as First-line Treatment in Advanced or Recurrent Endometrial Cancer in Spain

NCT06746116Advanced or Recurrent Endometrial Cancer

DrugDurvalumab

AstraZeneca

Phase 3

A Coruña, Alicante, Barakaldo, Barcelona, Córdoba, El Palmar, Girona, L'Hospitalet de Llobregat

2024-12-30

Recruiting

Early Transcatheter Mitral Valve Repair After Myocardial Infarction

NCT06282042Acute Mitral Regurgitation

Fundación para la Investigación Biosanitaria del Principado de Asturias

Not applicable

250

Alicante, Barcelona, L'Hospitalet de Llobregat, Santander, Córdoba, Las Palmas de Gran Canaria, Madrid, Málaga

2024-12-24

Recruiting

A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease

NCT06500702Focal Segmental Glomerulosclerosis, Glomerulonephritis Minimal Lesion

DrugsBrivekimig·Frexalimab·Rilzabrutinib

Sanofi

Phase 2

Seville, Barcelona, Córdoba, Madrid

2024-12-19

Recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

NCT06727604Graves' Disease

DrugIMVT-1402

Immunovant Sciences GmbH

Phase 2

240

Badalona, Barcelona, Córdoba, Granada, Madrid, Pamplona, Seville

2024-12-17

Active, closed

Phase 2 Study of Rapcabtagene Autoleucel in Myositis

NCT06665256Idiopathic Inflammatory Myopathies

DrugRapcabtagene autoleucel

Novartis Pharmaceuticals

Phase 2

Santiago Compostela, Santander, Pamplona, Barcelona, Córdoba, Madrid, Málaga, Salamanca

2024-12-17

By invitation

PrEveNtion of Biliary Events After Acute Pancreatitis in NonSUrgicaL PAtients: PENINSULA Trial

NCT06409741Acute Pancreatitis Due to Gallstones, Acute Pancreatitis

Hospital General Universitario de Alicante

Not applicable

126

Alicante, Córdoba, Madrid, Valencia, Valladolid

2024-12-16

Recruiting

Observational Study of the Effectiveness of Funded Drugs for Genitourinary Tumors.

NCT06724159Genitourinary Cancers

DrugsEnfortumab Vedotin·Darolutamide·Nivolumab

Spanish Oncology Genito-Urinary Group

Observational

500

Albacete, Alicante, Almería, Córdoba, Granada, Jaén, Jerez de la Frontera, Málaga

2024-12-13

By invitation

Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial)

NCT06723106Antiphospholipid Syndrome (APS), Bullous Pemphigoid (BP), Behçet's Syndrome (BS), Dermatomyositis (DM)

DrugRAY121

Chugai Pharmaceutical

Phase 1

144

Pamplona, Madrid, Barcelona, Córdoba, Seville, Valencia

2024-12-09

Recruiting

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

NCT06679140COVID-19 SARS-CoV-2 Infection

DrugIbuzatrelvir

Pfizer

Phase 3

2,330

A Coruña, Benalmádena, Córdoba, Badalona, Barcelona, Madrid, Vigo, Alicante

2024-12-08

Recruiting

Exploring Minor Proteins and Peptides in Human Milk: a Proteomic Analysis Across Lactation Stages

NCT06787963Low Birthweight Infant, Preterm, Very Low Birth Weight Preterms

Maimónides Biomedical Research Institute of Córdoba

Observational

150

Córdoba

2024-12-02

Recruiting

A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease

NCT06717698Chronic Kidney Disease

DrugSemaglutide

Novo Nordisk A/S

Phase 2

465

Barcelona, Córdoba, Getafe, L'Hospitalet de Llobregat, Madrid, Seville, Valencia

2024-12-02

Active, closed

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

NCT06694805HIV Infections

DrugsRpv La·B/F/TAF·Cabotegravir

ViiV Healthcare

Phase 3

326

L'Hospitalet de Llobregat, Bilbao, Puerto Real, Barcelona, Córdoba, Madrid, Málaga, Murcia

2024-12-02

Active, closed

Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)

NCT06635824PD-L1-positive, Locally Advanced (Unresectable Stage IIIB/C) or Metastatic NSCLC

DrugsDocetaxel·Pembrolizumab

Genmab

Phase 3

191

L'Hospitalet de Llobregat, Córdoba, Santiago de Compostela, Las Palmas de Gran Canaria, Pozuelo de Alarcón, Marbella, Pamplona, Alicante

2024-11-25

Recruiting

Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies

NCT06458712Advanced Cancers (Breast, Ovarian, mCRPC, Pancreatic Ductal Adenocarcinoma (PDAC), Brain Mets) With Specific Mutations (Homologous Recombination Deficiency)

Duke Street Bio Ltd

Phase 1

180

Logroño, Barcelona, Córdoba, Madrid, Málaga, Pamplona, Seville, Valencia

2024-11-21

Active, closed

Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

NCT06578247Leukemia

DrugQuizartinib

Daiichi Sankyo

Phase 3

700

Albacete, Alicante, Badalona, Barcelona, Burgos, Cáceres, Córdoba, Las Palmas

2024-11-19

Active, closed

Sarcopenia in Patients With Heart Failure

NCT06634316Sarcopenia

Maimónides Biomedical Research Institute of Córdoba

Not applicable

Córdoba

2024-11-15

Recruiting

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

NCT06632457Metabolic Dysfunction Associated Steatohepatitis

Boehringer Ingelheim

Phase 3

1,590

A Coruña, Barcelona, Córdoba, Madrid, Majadahonda, Pontevedra, Santiago de Compostela

2024-11-12

Recruiting

A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis

NCT06655155Systemic Sclerosis (SSc)

argenx

Phase 2

Barcelona, Córdoba, Sabadell

2024-11-11

Recruiting

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

NCT06456593Moderately to Severely Active Crohn Disease

DrugObefazimod

Abivax S.A.

Phase 2

212

Barcelona, Córdoba, Fuenlabrada, Huelva, Las Palmas de Gran Canaria, Santiago de Compostela, Seville, Valencia

2024-10-30

Active, closed

A Study of ZW191 in Participants With Solid Tumors

NCT06555744Advanced Solid Tumors

Zymeworks BC Inc.

Phase 1

145

Barcelona, Córdoba, Madrid, Valencia

2024-10-30

Recruiting

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

NCT06541704Age-related Macular Degeneration (AMD), Geographic Atrophy (GA)

DrugsCemdisiran·Pozelimab

Regeneron Pharmaceuticals

Phase 3

975

Córdoba, L'Hospitalet de Llobregat, Terrassa, Burjassot, Barcelona, Seville, Valencia, Zaragoza

2024-10-30

Active, closed

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

NCT06655896Scleroderma, Diffuse

DrugsRapcabtagene autoleucel·Rituximab

Novartis Pharmaceuticals

Phase 2

Santiago Compostela, Santander, Pamplona, Barcelona, Córdoba, Madrid, Málaga, Salamanca

2024-10-29

Active, closed

Multi-omics in Severe Asthma From Olive Pollen Allergy

NCT07721376Severe Asthma, Allergy and Asthma, Pollen; Allergy, Asthma

Maimónides Biomedical Research Institute of Córdoba

Observational

Córdoba

2024-10-28

Active, closed

A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy

NCT06413706Glioma

DrugsAbemaciclib·Temozolomide

Eli Lilly and Company

Phase 2

Barcelona, Córdoba, Esplugues de Llobregat, Madrid, Seville, Valencia

2024-10-25

Recruiting

The Sagittarius Trial

NCT06490536Colon Cancer Stage II, Colon Cancer Stage III

DrugsFolinic acid·Panitumumab·Pertuzumab·Temozolomide

IFOM ETS - The AIRC Institute of Molecular Oncology

Phase 3

700

Barcelona, Valencia, Córdoba, Madrid, Pamplona, Santander, Santiago de Compostela, Zaragoza

2024-10-22

Active, closed

RTX001 Autologous Engineered Macrophages for Liver Cirrhosis

NCT06823713End-stage Liver Disease (ESLD), Cirrhosis, Liver, Cirrhosis, Decompensated, Liver Diseases

Resolution Therapeutics Limited

Phase 1/2

Barcelona, Córdoba, Madrid, Seville, Valencia

2024-10-15

Recruiting

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

NCT06632444Metabolic Dysfunction Associated Steatohepatitis (MASH), Liver Fibrosis

Boehringer Ingelheim

Phase 3

1,800

A Coruña, Barcelona, Córdoba, Madrid, Majadahonda, Pontevedra, Santander, Santiago de Compostela

2024-10-14

Recruiting

Safety and Effectiveness of Short-Term Single AntiPlatelet Therapy After Left Atrial Appendage Closure With the LAmbre Device in Patients With Nonvalvular Atrial Fibrillation: A Multinational Real-world Registry

NCT06620757Atrial Fibrillation

Fundación EPIC

Observational

234

A Coruña, Aravaca, Barcelona, Córdoba, Fuencarral-El Pardo, Gijón, L'Hospitalet de Llobregat, Las Palmas de Gran Canaria

2024-10-10

Active, closed

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)

NCT06516965Prurigo Nodularis

DrugPovorcitinib

Incyte Corporation

Phase 3

346

Alicante, Badalona, Barcelona, Córdoba, Granada, Madrid, Majadahonda, Manises

2024-10-10

Active, closed

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

NCT06598943Ulcerative Colitis, Ulcerative Colitis Chronic

DrugMirikizumab

Eli Lilly and Company

Phase 2

143

Barcelona, Ciudad Real, Córdoba, Huelva, Las Palmas de GC, Madrid, Santiago de Compostela, Seville

2024-10-10

Recruiting

A Clinical Trial to Define the Best Strategy for the Management of Heart Failure in Elderly Patients

NCT06578078Heart Failure, Chronic Kidney Diseases

DrugSodium Zirconium Cyclosilicate

Fundación para la Investigación del Hospital Clínico de Valencia

Phase 3

Alcorcón, Leganés, Albacete, Burgos, Córdoba, Valencia

2024-10-03

Recruiting

Study on Safety and Efficacy of Two Doses of PRS CK STORM in the Modulation of the Cytokine Storm in Patients With Acute Respiratory Infection Caused by SARS-Cov-2, Influenza A, Influenza B and Respiratory Syncytial Virus (RSV)

NCT06684379SARS-CoV-2, Influenza, Human, Respiratory Syncytial Virus Infections, Respiratory Distress Syndrome

PEACHES BIOTECH

Phase 1/2

Alcalá de Henares, Fuenlabrada, Córdoba

2024-10-02

Recruiting

A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer

NCT06545955Non-muscle Invasive Bladder Cancer With Carcinoma in Situ

DrugsNadofaragene Firadenovec·Docetaxel·Gemcitabine·Pembrolizumab

Ferring Pharmaceuticals

Phase 3

250

Santander, Barcelona, Córdoba, A Coruña, Alcorcón, Madrid, Pamplona, Bilbao

2024-10-01

Recruiting

Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer

NCT06510374Intermediate Risk Non-Muscle Invasive Bladder Cancer

DrugNadofaragene Firadenovec

Ferring Pharmaceuticals

Phase 3

454

Santander, Barcelona, Córdoba, A Coruña, Granada, Alcorcón, Madrid, Bilbao

2024-10-01

Recruiting

A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

NCT06635148Geographic Atrophy, Macular Degeneration

Janssen Research & Development, LLC

Phase 2/3

274

Barcelona, Burjassot, Córdoba, Madrid, Majadahonda, Pamplona, Sant Cugat del Vallès, Seville

2024-09-19

Active, closed

Study of Bepirovirsen in Participants Living With Human Immunodeficiency Virus and Chronic Hepatitis B Virus Infection (B-Focus)

NCT06497504Hepatitis B

DrugBepirovirsen

GlaxoSmithKline

Phase 2

153

Barcelona, Córdoba, Madrid

2024-09-17

Recruiting

European Registry of Next Generation Imaging in Advanced Prostate Cancer

NCT06866782Prostate Cancer, Advanced Prostate Cancer, Metastatic Prostate Cancer (mPC)

Fundacio Puigvert

Observational

600

Barcelona, Córdoba, Madrid, San Cristóbal de La Laguna, Santander, Santiago de Compostela

2024-09-17

Recruiting

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

NCT06572384Lung Diseases, Interstitial

DrugBelimumab

GlaxoSmithKline

Phase 3

440

Pamplona Iruna, Barcelona, Córdoba, Granada, Madrid, Málaga, Santander, Seville

2024-09-11

Active, closed

A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)

NCT06581198Lupus Erythematosus, Systemic, Lupus Nephritis

DrugRapcabtagene autoleucel

Novartis Pharmaceuticals

Phase 2

179

Santiago Compostela, Santander, Pamplona, Barcelona, Córdoba, Madrid, Salamanca, Valencia

2024-09-04

Recruiting

Zanubrutinib With Obinutuzumab in Untreated Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

NCT06544785Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma

DrugsZanubrutinib Product·Zanubrutinib·Obinutuzumab

PETHEMA Foundation

Phase 2

106

Alicante, Barcelona, Córdoba, Las Palmas de Gran Canaria, Madrid, Marbella, Málaga, Oviedo

2024-09-02

Active, closed

Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)

NCT06564142Immunoglobulin A Nephropathy

DrugPovetacicept

Alpine Immune Sciences Inc, A Subsidiary of Vertex

Phase 3

605

Barcelona, Córdoba, Lleida, Madrid, Pamplona, Santiago de Compostela, Seville, Valencia

2024-08-30

Active, closed

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Active Thyroid Eye Disease (TED)

NCT06625411Thyroid Eye Disease

DrugVRDN-003

Viridian Therapeutics, Inc.

Phase 3

132

Santiago de Compostela, Seville, Córdoba, Madrid, Zaragoza

2024-08-27

Active, closed

An Efficacy, Safety, and Tolerability Study of VRDN-003 in Participants With Chronic Thyroid Eye Disease (TED)

NCT06625398Thyroid Eye Disease

DrugVRDN-003

Viridian Therapeutics, Inc.

Phase 3

204

Santiago de Compostela, Córdoba, Madrid, Seville, Zaragoza

2024-08-27

Recruiting

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

NCT06371417Antiphospholipid Syndrome (APS), Bullous Pemphigoid (BP), Behçet's Syndrome (BS), Dermatomyositis (DM)

DrugRAY121

Chugai Pharmaceutical

Phase 1

144

Pamplona, Madrid, Barcelona, Córdoba, Seville, Valencia

2024-08-19

Active, closed

A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of Vonaprument (Formerly ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy (GA)

NCT06510816Geographic Atrophy

DrugVonaprument

Annexon, Inc.

Phase 3

659

Valencia, Barcelona, Córdoba, Madrid, Majadahonda, Sant Cugat del Vallès, Santiago de Compostela, Seville

2024-07-30

Active, closed

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

NCT06459180Cervical Cancer

DrugsTisotumab Vedotin·Vinorelbine·Topotecan·Sacituzumab tirumotecan

Merck Sharp & Dohme LLC

Phase 3

686

Barcelona, L'Hospitalet de Llobregat, Girona, Madrid, Valencia, Córdoba

2024-07-24

Recruiting

PulseSelect™ PFA Global Registry

NCT06393920Atrial Fibrillation

Medtronic Cardiac Ablation Solutions

Observational

1,950

Córdoba, Málaga, Salamanca

2024-07-23

Active, closed

PHESGO Maintenance After T-DXd Short Induction for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer

NCT06172127HER2-positive Breast Cancer

DrugsPhesgo·Trastuzumab deruxtecan

MedSIR

Phase 2

165

Seville, Alicante, Barcelona, Bilbao, Castellon, Córdoba, Granada, León

2024-07-22

Recruiting

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

NCT06282575Biliary Tract Cancer

DrugsZanidatamab·Durvalumab·Gemcitabine·Cisplatin

Jazz Pharmaceuticals

Phase 3

286

Santiago de Compostela, Barcelona, Córdoba, Madrid, Málaga, Pamplona, Seville, Valencia

2024-07-19

Recruiting

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

NCT06252649Metastatic Colorectal Cancer

DrugsLumakras·Sotorasib·Bevacizumab-awwb·Panitumumab

Amgen

Phase 3

450

Córdoba, Granada, Málaga, Seville, Zaragoza, Santander, Burgos, Badalona

2024-07-17

Active, closed

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria

NCT06445023Chronic Spontaneous Urticaria

DrugBarzolvolimab

Celldex Therapeutics

Phase 3

963

Sabadell, Alicante, Barcelona, Córdoba, Madrid, Salamanca, Villarreal de Huerva

2024-07-11

Recruiting

A Study to Evaluate the Safety,Tolerability, Pharmacokinetics and Clinical Activity of Mocertatug Rezetecan for Injection in Participants With Advanced Solid Tumors (BEHOLD-1)

NCT06431594Solid Tumors, Neoplasms

DrugMocertatug rezetecan

GlaxoSmithKline

Phase 1

675

Barcelona, Córdoba, Girona, Madrid, Pozuelo de AlarcOn Madr

2024-07-02

Recruiting

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

NCT06463587Generalized Myasthenia Gravis

DrugCladribine

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

Phase 3

264

Badalona, Córdoba, Oviedo, Barcelona, Valencia

2024-06-25

Recruiting

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)

NCT06455449Polymyositis, Dermatomyositis

AstraZeneca

Phase 3

240

A Coruña, Barcelona, Córdoba, L'Hospitalet de Llobregat, Madrid, Sabadell, Valladolid

2024-06-20

Active, closed

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

NCT06388733Glioblastoma, GBM, Brain Neoplasms, Adult, Malignant, Brain Tumor

DrugsTemodar·Niraparib·Temozolomide

Ivy Brain Tumor Center

Phase 3

450

Barcelona, Córdoba, Girona, Madrid, Pamplona, Salamanca, Seville

2024-06-19

Active, closed

A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)

NCT06411249Systemic Lupus Erythematosus

DrugBelimumab

GlaxoSmithKline

Phase 4

303

Barcelona, Castellon, Córdoba, Murcia, Valladolid, VigoPontevedra, Villajoyosa

2024-06-06

Recruiting

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

NCT06056297Neutropenia

X4 Pharmaceuticals

Phase 3

176

Barcelona, Cáceres, Córdoba, Las Palmas de Gran Canaria, Madrid, Santander, Seville, Valencia

2024-06-06

Recruiting

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

NCT06112314Advanced Melanoma

DrugsBrenetafusp·Relatlimab·Opdivo·Nivolumab

Immunocore Ltd

Phase 3

680

Santander, El Palmar, A Coruña, Barcelona, Córdoba, Granada, Las Palmas de Gran Canaria, Madrid

2024-06-05

Active, closed

T-DXd Therapy for HER2-low Breast Cancer Patients With Brain Metastases

NCT06048718Breast Cancer, Metastatic Breast Cancer

DrugTrastuzumab deruxtecan

MedSIR

Phase 2

Alicante, Barcelona, Bilbao, Córdoba, Granada, Madrid, Seville, Valencia

2024-06-05

Recruiting

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

NCT06439277Obesity, Weight Gain

DrugTirzepatide

Eli Lilly and Company

Phase 3

300

Barcelona, Córdoba, Madrid, Málaga, Valencia

2024-06-03

Active, closed

A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia

NCT05963074Leukemia, Lymphocytic, Chronic, B-Cell, Small Lymphocytic Lymphoma

DrugsVenclyxto·Ibrutinib·Venclexta·Venetoclax

Janssen Research & Development, LLC

Phase 2

333

Barcelona, Córdoba, Madrid, Santander, Santiago de Compostela

2024-05-30

Recruiting

A New Technological Intervention to Address Childhood Obesity:

NCT06409962Body Weight, Dyslipidemias, Musculoskeletal Diseases

Universidad de Córdoba

Not applicable

215

Córdoba

2024-05-30

Recruiting

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

NCT06419374Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

DrugPegozafermin

89bio, Inc.

Phase 3

762

Almería, Badalona, Barcelona, Córdoba, Madrid, Málaga, Pontevedra, Santander

2024-05-24

Recruiting

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

NCT06203210Small Cell Lung Cancer

DrugsAmrubicin·Ifinatamab Deruxtecan·Lurbinectedin·Topotecan

Daiichi Sankyo

Phase 3

540

Barcelona, Córdoba, Jaén, Jerez de la Frontera, L'Hospitalet de Llobregat, Las Palmas de Gran Canaria, Madrid, Málaga

2024-05-21

Active, closed

A Study to Evaluate the Safety and Biomarker Effects of RO7269162 in Participants at Risk for or at the Prodromal Stage of Alzheimer's Disease (AD)

NCT06402838Alzheimer's Disease

Hoffmann-La Roche

Phase 2

256

Sant Cugat del Vallès, Donostia / San Sebastian, Pozuelo de Alarcón, Salamaca, Barcelona, Córdoba, Madrid, Seville

2024-05-02

Recruiting

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

NCT05485961End Stage Kidney Disease

DrugClazakizumab

CSL Behring

Phase 2/3

3,110

Alcobendas, Barcelona, Córdoba, Girona, Granada, Guadalajara, Lleida, Madrid

2024-04-27

Active, closed

Transmural Healing and Disease-Modifying Effect of Guselkumab in Crohn's Disease Patients

NCT06408935Crohn's Disease

DrugsTremfya·Guselkumab

Janssen-Cilag Ltd.

Phase 3

120

Alicante, Córdoba, Ferrol, Madrid, Valencia, Vigo

2024-04-17

Recruiting

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

NCT06312176Breast Neoplasms

DrugsLiposomal doxorubicin·Abraxane·Xeloda·Sacituzumab tirumotecan

Merck Sharp & Dohme LLC

Phase 3

1,200

Pozuelo de Alarcón, Madrid, Valencia, Barcelona, Córdoba, Seville

2024-04-14

Active, closed

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

NCT06245408Sjögren's Syndrome (SS)

DrugDazodalibep

Amgen

Phase 3

434

Córdoba, Bilbao, A Coruña, Madrid, San Cristóbal de La Laguna, Santa Coloma de Gramenet(Barcelona), Seville, Vitoria-Gasteiz

2024-04-08

Active, closed

Comparison Between Optical Coherence Tomography and Intravascular Ultrasound for Intermediate Left Main Coronary Artery Lesions

NCT06272643Coronary Disease

Fundación EPIC

Observational

153

Alicante, Aravaca, Barcelona, Cadiz, Córdoba, El Palmar, Gijón, Huelva

2024-04-04

Active, closed

A PoC Study to Evaluate Treatments' Efficacy by Monitoring MRD Using ctDNA in HR-positive/HER2-negative EBC Population

NCT05708235Breast Cancer

DrugsGiredestrant·Inavolisib·Abemaciclib

MedSIR

Phase 2

976

A Coruña, Alicante, Barcelona, Bilbao, Castellon, Córdoba, Elche, Girona

2024-04-01

Recruiting

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

NCT06072781Low Grade Serous Ovarian Cancer

DrugsAvutometinib·Defactinib·Pegylated liposomal doxorubicin·Anastrozole

Verastem, Inc.

Phase 3

270

El Palmar, Donostia / San Sebastian, Barcelona, Córdoba, Madrid, Santiago de Compostela, Valencia

2024-03-18

Recruiting

A Clinical Investigation to Evaluate Microwave Imaging Via MammoWave® in a Population-based Screening Program for Early Breast Cancer Detection

NCT06291896Women's Health: Neoplasm of Breast

Umbria Bioengineering Technologies

Not applicable

10,000

Córdoba, Murcia, Toledo

2024-03-15

Recruiting

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

NCT05923073Crohn's Disease

DrugsTremfya·Guselkumab

Janssen Research & Development, LLC

Phase 3

120

Córdoba, Sabadell, Valencia

2024-03-13

Recruiting

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

NCT05509777Crohn's Disease

DrugMirikizumab

Eli Lilly and Company

Phase 3

Córdoba, Sabadell, Valencia

2024-03-13

Recruiting

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

NCT06318169Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

DrugPegozafermin

89bio, Inc.

Phase 3

1,350

Barcelona, Córdoba, Madrid, Majadahonda, Málaga, Pontevedra, Santander, Santiago de Compostela

2024-03-13

Recruiting

Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With STEMI

NCT06353594ST Elevation Myocardial Infarction

Hospital Universitario La Fe

Not applicable

1,272

Huelva, Valencia, A Coruña, Burgos, Castelló, Córdoba, Elche, Granada

2024-03-11

Recruiting

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

NCT05646381Aortic Stenosis

DrugPelacarsen

Novartis Pharmaceuticals

Phase 2

502

Cáceres, Córdoba, Madrid, Salamanca, Valencia

2024-03-07

Active, closed

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

NCT06292013Atherosclerotic Cardiovascular Disease (ASCVD), Elevated Lp(a)

DrugLepodisiran

Eli Lilly and Company

Phase 3

17,300

A Coruña, Alcorcón, Badalona, Barcelona, Córdoba, Denia, El Palmar, Murcia, Ferrol

2024-03-05

Recruiting

Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

NCT05935215Atypical Hemolytic Uremic Syndrome

DrugIptacopan

Novartis Pharmaceuticals

Phase 3

Santiago Compostela, Barcelona, Córdoba, Málaga, Seville, Valencia

2024-02-28

Recruiting

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

NCT06283966COPD (Chronic Obstructive Pulmonary Disease)

AstraZeneca

Phase 3

5,250

Alicante, Badia Del Vallès, Barakaldo, Barcelona, Castro Urdiales, Córdoba, Granada, Madrid

2024-02-21

Active, closed

Study to Assess Speed of Onset and Durability of Effectiveness of Upadacitinib in Adult Participants With Moderate to Severe Crohn's Disease (CD) in Real World Clinical Practice.

NCT05930275Crohn's Disease

AbbVie

Observational

1,200

Sant Joan Despí, Jerez de la Frontera, Córdoba, Las Palmas de Gran Canaria, Leganés, Oviedo, Galdakao, Barcelona

2024-02-19

Active, closed

A 52-Week Study to Learn About the Safety and Effects of Ritlecitinib in Participants With Nonsegmental Vitiligo

NCT06163326Vitiligo

DrugRitlecitinib

Pfizer

Phase 3

394

Córdoba, Barcelona, Las Palmas de Gran Canaria, Madrid

2024-01-19

Active, closed

A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)

NCT06109272Hepatocellular Carcinoma

DrugsLivmoniplimab·Budigalimab·Tremelimumab·Atezolizumab

AbbVie

Phase 2/3

Santander, Majadahonda, Barcelona, Córdoba, Madrid, Seville, Zaragoza

2024-01-11

Active, closed

Pasireotide s.c. in Patients With Post-Bariatric Hypoglycaemia

NCT05928390Post-Bariatric Hypoglycemia

RECORDATI GROUP

Phase 2

Barcelona, Córdoba, Girona, Madrid

2024-01-04

Active, closed

Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma

NCT05948475Cholangiocarcinoma

DrugTinengotinib

TransThera Sciences (Nanjing), Inc.

Phase 3

200

Barcelona, Córdoba, Madrid, Pamplona, Santiago de Compostela, Zaragoza

2023-12-20

Active, closed

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

NCT06141473Multiple Sclerosis

DrugsCholestyramine·Activated Charcoal·Teriflunomide·Frexalimab

Sanofi

Phase 3

1,655

Murcia, Barcelona, Barakaldo, Las Palmas de Gran Canaria, Pozuelo de Alarcón, Pontevedra, Seville, Córdoba

2023-12-13

Active, closed

Sacituzumab Tirumotecan (MK-2870) in Post Platinum and Post Immunotherapy Endometrial Cancer (MK-2870-005)

NCT06132958Endometrial Cancer

DrugsAbraxane·Adriamycin·Sacituzumab tirumotecan·Taxol

Merck Sharp & Dohme LLC

Phase 3

710

L'Hospitalet de Llobregat, Girona, Madrid, Valencia, Barcelona, Córdoba

2023-12-06

Active, closed

Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents

NCT06120491Metastatic Castration-Sensitive Prostate Cancer

DrugsSaruparib·Zytiga·Xtandi·Abiraterone acetate

AstraZeneca

Phase 3

1,898

Barcelona, Córdoba, L'Hospitalet de Llobregat, Lugo, Madrid, Sabadell, Valencia

2023-11-21

Active, closed

Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension.

NCT06042478Chronic Spontaneous Urticaria

DrugsOmalizumab·Remibrutinib

Novartis Pharmaceuticals

Phase 3

470

Granada, Barcelona, Córdoba, Las Palmas GC, Valencia

2023-11-15

Active, closed

A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Adult Patients With Moderate-to-Severe Atopic Dermatitis

NCT06136741Moderate to Severe Atopic Dermatitis

DrugRezpegaldesleukin

Nektar Therapeutics

Phase 2

396

Alicante, Córdoba, Granada, Seville, Zaragoza

2023-11-15

Active, closed

A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2

NCT06003231Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Endometrial Neoplasms, Head and Neck Neoplasms

DrugDisitamab Vedotin

Seagen, a wholly owned subsidiary of Pfizer

Phase 2

120

Pamplona, Córdoba, Madrid

2023-11-14

Active, closed

A 104-Week Study of Ritlecitinib Oral Capsules in Adults With Nonsegmental Vitiligo (Active and Stable) Tranquillo 2

NCT06072183Stable Nonsegmental Vitiligo, Active Nonsegmental Vitiligo

DrugRitlecitinib

Pfizer

Phase 3

1,571

Córdoba, Badalona, L'Hospitalet de Llobregat, Santiago de Compostela, Madrid, Barcelona, Valencia, Zaragoza

2023-11-08

Recruiting

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

NCT05696626Metastatic Breast Cancer

DrugsAbemaciclib·Fulvestrant

LeonaBio

Phase 3

600

Barcelona, Córdoba, Madrid, Málaga, Pamplona, Valencia

2023-10-31

Active, closed

A Randomized, Double-blind 2-arm, Followed by an Open-label 1-arm, NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome.

NCT05985915Sjogrens Syndrome

DrugIanalumab

Novartis Pharmaceuticals

Phase 3

612

Badalona, Sabadell, Bilbao, Santander, Vigo, A Coruña, Barcelona, Córdoba

2023-10-27

Recruiting

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

NCT06012240Alopecia Areata

DrugUpadacitinib

AbbVie

Phase 3

1,500

L'Hospitalet de Llobregat, Fuenlabrada, Barcelona, Córdoba, Madrid, Valencia

2023-10-11

Active, closed

Study in Patients With Decompensated Liver Cirrhosis

NCT06380335Liver Cirrhosis

Resolution Therapeutics Limited

Observational

Córdoba, Madrid

2023-10-10

Active, closed

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

NCT06008756Arteriosclerosis, Hypercholesterolaemia

DrugEnlicitide Decanoate

Merck Sharp & Dohme LLC

Phase 3

14,550

Torrevieja, Córdoba, Málaga, Seville, Calella, Barcelona, Centelles, L'Hospitalet de Llobregat

2023-10-09

By invitation

A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

NCT06044337Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus

DrugLitifilimab

Biogen

Phase 3

306

Valladolid, Córdoba, Majadahonda, Barcelona, Seville

2023-10-03

Active, closed

A Phase III Trial Comparing Tisagenlecleucel to Standard of Care (SoC) in Adult Participants With r/r Follicular Lymphoma

NCT05888493Follicular Lymphoma (FL)

DrugTisagenlecleucel

Novartis Pharmaceuticals

Phase 3

109

Santiago Compostela, L'Hospitalet de Llobregat, Santander, El Palmar, Barcelona, Córdoba, Madrid, Salamanca

2023-10-02

Not yet open

Efficacy of Letermovir in Preventing Cytomegalovirus (CMV) Infection in Lung Transplant Recipients vs. Valganciclovir.

NCT06057194Infections, Cytomegalovirus

DrugLetermovir

Maimónides Biomedical Research Institute of Córdoba

Phase 2

Córdoba

2023-10

Recruiting

Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)

NCT06079671Locally Advanced Cervical Cancer

DrugVolrustomig

AstraZeneca

Phase 3

800

A Coruña, Barcelona, Córdoba, Girona, Hospitalet deLlobregat, Madrid, Palma de Mallorca, Valencia

2023-09-22

Active, closed

Study to Evaluate Adverse Events, and Change in Disease Activity, When Intravenously (IV) Infused With Livmoniplimab in Combination With IV Infused Budigalimab in Adult Participants With Hepatocellular Carcinoma (HCC)

NCT05822752Hepatocellular Carcinoma

DrugsLivmoniplimab·Budigalimab·Sorafenib·Lenvatinib

AbbVie

Phase 2

130

Santander, Córdoba, Majadahonda, Pamplona, Barcelona, Madrid, Seville, Zaragoza

2023-09-21

Active, closed

A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)

NCT05869955Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathy, Systemic Sclerosis, Rheumatoid Arthritis

DrugsZola-cel·Tocilizumab·Fludarabine·Cyclophosphamide

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Phase 1

270

Barcelona, Santander, Córdoba, Málaga

2023-09-13

Recruiting

Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)

NCT05722938Community-acquired Pneumonia

Biotest

Phase 3

590

Palma de Mallorca, Sabadell, Terrassa, Córdoba, Majadahonda, Pamplona, Oviedo, Barcelona

2023-09-09

Recruiting

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

NCT06051617Primary Biliary Cholangitis

DrugSeladelpar

Gilead Sciences

Phase 3

402

A Coruña, Alcorcón, Badalona, Barcelona, Córdoba, Málaga, Santander, Seville

2023-09-07

Active, closed

Effectiveness of Exergaming in Adittion to Conventional Treatment for Physical Therapy in People with Multiple Sclerosis

NCT06196866Multiple Sclerosis

Universidad de Córdoba

Not applicable

Córdoba

2023-09-01

Active, closed

Enlighten Study: The EV-ICD Post Approval Registry

NCT06048731Ventricular Arrhythmia, Tachycardia

Medtronic

Observational

1,000

A Coruña, Barcelona, Córdoba, Girona, Granada, Valencia

2023-09-01

Active, closed

A Study of Efficacy and Safety of Rosnilimab in Subjects with Moderate to Severe Rheumatoid Arthritis (RENOIR)

NCT06041269Rheumatoid Arthritis

DrugRosnilimab

AnaptysBio, Inc.

Phase 2

420

Bilbao, Santiago de Compostela, Córdoba

2023-08-31

Active, closed

A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma Exacerbations

NCT06052267Asthma

Teva Branded Pharmaceutical Products R&D LLC

Phase 3

2,772

Badalona, Barcelona, Córdoba, Madrid, Sabadell, Santiago de Compostela, Seville, Valencia

2023-08-30

Active, closed

A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

NCT05797610Primary IgA Nephropathy

Hoffmann-La Roche

Phase 3

459

Lleida, Barcelona, Córdoba, Lugo, Madrid, Seville

2023-08-08

Recruiting

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

NCT05855200Colonic Neoplasms, Neoplasms, Colon

DrugsCapeox·Dostarlimab·Folfox

GlaxoSmithKline

Phase 3

892

Badajoz, BaracaldoVizcaya, Barcelona, Córdoba, Donostia / San Sebastian, Elche Alicante, Granada, Jaén

2023-08-01

Recruiting

OSIREAL - Osimertinib RWE on EGFRm NSCLC in Spain

NCT06068049Non-small Cell Lung Cancer

AstraZeneca

Observational

500

A Coruña, Alicante, Barcelona, C Rdoba, El Palmar, Girona, Granada, Jaén

2023-07-28

Active, closed

Open-Label Extension (OLE) Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Hypertension

NCT05968430Hypertension

Mineralys Therapeutics Inc.

Phase 3

1,076

Badajoz, Córdoba, Granada, Valencia

2023-07-14

Recruiting

PICAROS - Acalabrutinib RWE on 1L CLL in Spain

NCT05999877Chronic Lymphocytic Leukemia

AstraZeneca

Observational

315

Almería, Córdoba, Granada, Jaén, Marbella, Málaga, Seville, Zaragoza

2023-07-11

Recruiting

Omega-3 Fatty Acids and Nutritional Support in Gastrointestinal Cancer

NCT06015971Sarcopenia

Maimónides Biomedical Research Institute of Córdoba

Not applicable

Córdoba

2023-07-01

Active, closed

Durvalumab and Tremelimumab as First Line Treatment in Participants With Advanced Hepatocellular Carcinoma (HCC)

NCT05883644Advanced Hepatocellular Carcinoma

DrugsTremelimumab·Durvalumab

AstraZeneca

Phase 3

111

Barcelona, Córdoba, Madrid, Pamplona

2023-06-27

Recruiting

Ganciclovir Resistant/Refractory Cytomegalovirus Infection in SOT Recipients and HSCT Patients

NCT05234723Cytomegalovirus Infections

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Observational

100

Barcelona, Córdoba, Madrid

2023-06-19

Active, closed

A Real-life Study of the Use of Cabotegravir Plus Rilpivirine Long-acting in ART-experienced Pre-treated People With HIV

NCT06518408Human Immunodeficiency Virus

University Hospital Virgen de las Nieves

Observational

287

Granada, Logroño, Murcia, Cadiz, Córdoba, Jaén, Madrid, Palma de Mallorca

2023-06-01

Recruiting

A Study to Evaluate the Efficacy and Safety of QMF149 (Indacaterol Acetate/Mometasone Furoate) Versus Budesonide in Children From 6 to Less Than 12 Years of Age With Asthma

NCT05562466Asthma

DrugBudesonide

Novartis Pharmaceuticals

Phase 3

200

Esplugues, Sabadell, Barcelona, Córdoba, Madrid, Málaga

2023-05-11

Active, closed

A Study to Evaluate ATP150/ATP152/ATP162, VSV-GP154 and Ezabenlimab in Patients With Pancreatic Ductal Adenocarcinoma

NCT05846516Pancreatic Ductal Adenocarcinoma

DrugEzabenlimab

Boehringer Ingelheim

Phase 1

Barcelona, Córdoba, Madrid

2023-05-11

Active, closed

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy

NCT05840211Locally Advanced or Unresectable Metastatic Breast Cancer, Stage IV Breast Cancer

DrugsAbraxane·Xeloda·Sacituzumab Govitecan·Taxol

Gilead Sciences

Phase 3

654

Barcelona, Bilbao, Córdoba, Elche, Jaén, Madrid, Salamanca, Santiago de Compostela

2023-05-08

Active, closed

Equity in Modifying Plaque Of WomEn With UndeRtreated Calcified Coronary Artery Disease

NCT05755711Coronary Artery Disease

Shockwave Medical, Inc.

Observational

399

Santiago de Compostela, Barcelona, Córdoba, Madrid

2023-05-03

Active, closed

An Early Access Study of Ivosidenib in Patients With a Pretreated Locally Advanced or Metastatic Cholangiocarcinoma

NCT05876754Cholangiocarcinoma

DrugIvosidenib

Servier Affaires Médicales

Phase 3

299

A Coruña, Barcelona, Córdoba, Elche, Madrid, Pamplona, Santander

2023-05-03

Active, closed

A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma

NCT05805501Renal Cell Carcinoma

DrugsTobemstomig·Tiragolumab·Axitinib·Keytruda

Hoffmann-La Roche

Phase 2

199

Córdoba, Barcelona, Madrid, Seville, Valencia

2023-04-21

Active, closed

Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma

NCT05611931Endometrial Cancer

DrugSelinexor

Karyopharm Therapeutics Inc

Phase 3

257

Donostia / San Sebastian, Zaragoza, Badalona, Barcelona, Córdoba, Girona, Granada, Madrid

2023-04-18

Recruiting

Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

NCT05555589Neurotrophic Keratopathy

ReGenTree, LLC

Phase 3

Barcelona, Córdoba, Oviedo, Valencia

2023-04-11

Active, closed

A Study Evaluating the Effect of Filgotinib in Participants With Active Axial Spondyloarthritis

NCT05785611Axial Spondyloarthritis

DrugFilgotinib

Alfasigma S.p.A.

Phase 3

495

Alicante, Barcelona, Bilbao, Córdoba, Madrid, Santander, Santiago de Compostela, Seville

2023-04-05

Active, closed

Open Label, Long-term Study Evaluating Safety and Efficacy of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis

NCT05769777Dermatitis Atopic

DrugAmlitelimab

Sanofi

Phase 2

999

Badalona, Sabadell, Alicante, Córdoba, Madrid, Valencia

2023-04-03

Active, closed

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer

NCT05445778Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer

DrugsMirvetuximab Soravtansine·Bevacizumab

AbbVie

Phase 3

520

A Coruña, L'Hospitalet de Llobregat, Córdoba, Málaga, Pamplona, Barcelona, Girona, Madrid

2023-03-15

Active, closed

REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels

NCT05669755Cardiovascular Disease

DrugsCagrilintide·Semaglutide

Novo Nordisk A/S

Phase 3

7,101

Fuenlabrada, Alzira, Antequera, Barcelona, Castilleja de la Cuesta, Córdoba, Las Palmas de Gran Canaria, Madrid

2023-03-01

Active, closed

Efficacy and Safety of ATX01 in Adult Patients With CIPN (Chemotherapy-induced Peripheral Neuropathy)

NCT05593614Chemotherapy-induced Peripheral Neuropathy

AlgoTherapeutix

Phase 2

276

Barcelona, Córdoba, Jaén, Madrid, Reus, Valencia

2023-02-28

Active, closed

A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE

NCT05702034Ischemic Stroke; Ischemic Attack, Transient

DrugMilvexian

Janssen Research & Development, LLC

Phase 3

12,523

A Coruña, Albacete, Alicante, Badalona, Barakaldo, Barcelona, Córdoba, Girona

2023-02-15

Active, closed

Effectiveness of a Combined mHealth-CBT Psychological Intervention to Improve Psychological Well-Being in Young Patients With T1D

NCT06450730Diabetes Mellitus, Type 1

Maimónides Biomedical Research Institute of Córdoba

Not applicable

122

Córdoba

2023-02-11

Recruiting

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies

NCT05682378Heterozygous or Homozygous Familial Hypercholesterolemia

DrugInclisiran

Novartis Pharmaceuticals

Phase 3

195

Pamplona, Oviedo, A Coruña, Córdoba

2023-02-10

Active, closed

A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

NCT05578976Diffuse Large B-Cell Lymphoma

DrugsEpcoritamab·Vincristine·Doxorubicin·Prednisone

Genmab

Phase 3

900

Badalona, Barcelona, L'Hospitalet de Llobregat, Córdoba, Madrid, El Palmar, Pamplona, Valencia

2023-02-08

Active, closed

Metabolome and Microbiome Impact on Acute GVHD in Recipients of Hematopoietic Transplant

NCT05186857Graft-versus-host Disease

Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Observational

Santander, Córdoba, Granada, Madrid, Málaga, Salamanca, Seville, Valencia

2023-01-23

Active, closed

ABTECT - Maintenance

NCT05535946Ulcerative Colitis

DrugObefazimod

Abivax S.A.

Phase 3

1,116

Córdoba, Santiago de Compostela, Las Palmas de Gran Canaria, Fuenlabrada, Barcelona, Girona, Huelva, Madrid

2023-01-16

Active, closed

First in Human Study of IMGN151 in Recurrent Gynaecological Cancers

NCT05527184Endometrial Cancer, High Grade Serous Adenocarcinoma of Ovary, Primary Peritoneal Carcinoma, Fallopian Tube Cancer

DrugIMGN151

AbbVie

Phase 1

256

Badalona, Córdoba, Barcelona, Madrid, Valencia

2023-01-11

Active, closed

Study of XL092 + Nivolumab vs Sunitinib in Subjects With Advanced or Metastatic Non-Clear Cell Renal Cell Carcinoma

NCT05678673Non-Clear Cell Renal Cell Carcinoma

DrugsSunitinib Malate·Zanzalintinib·Sunitinib·Opdivo

Exelixis

Phase 3

317

Palma de Mallorca, Majadahonda, Barcelona, Córdoba, Girona, Madrid, Málaga, Oviedo

2023-01-01

Active, closed

Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)

NCT05024773Bladder Carcinoma in Situ (CIS)

Fidia Farmaceutici s.p.a.

Phase 3

130

Barcelona, Valencia, Bilbao, Córdoba, Granada, Madrid, Málaga

2022-12-29

Recruiting

Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

NCT05232916Breast Cancer

Greenwich LifeSciences, Inc.

Phase 3

2,250

Albacete, Alicante, Badajoz, Barcelona, Cáceres, Córdoba, El Palmar, Fuenlabrada

2022-12-16

Recruiting

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

NCT05287126Ulcerative Colitis

DrugEtrasimod

Pfizer

Phase 2

Santiago de Compostela, Sabadell, Barcelona, Córdoba

2022-12-16

Active, closed

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial

NCT05581303Atherosclerotic Cardiovascular Disease

DrugOlpasiran

Amgen

Phase 3

7,297

Córdoba, Málaga, Seville, Zaragoza, León, Badalona, Barcelona, L'Hospitalet de Llobregat

2022-12-14

Active, closed

CORE-OLE: A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG)

NCT05681351Severe Hypertriglyceridemia

DrugOlezarsen

Ionis Pharmaceuticals, Inc.

Phase 3

885

A Coruña, Badalona, Barcelona, Córdoba, Jaén, Madrid, Málaga, Sabadell

2022-12-13

Recruiting

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

NCT05633654Triple Negative Breast Cancer

DrugsXeloda·Sacituzumab Govitecan·Keytruda·Capecitabine

Gilead Sciences

Phase 3

1,514

A Coruña, Badalona, Barakaldo, Barcelona, Castellon, Cáceres, Córdoba, Donostia / San Sebastian

2022-12-12

Active, closed

Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis

NCT05556096Generalized Myasthenia Gravis

Alexion Pharmaceuticals, Inc.

Phase 3

260

Badalona (Barcelona), Córdoba, L'Hospitalet de Llobregat, Madrid, Málaga, Seville

2022-11-21

Active, closed

A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-Risk Myelodysplastic Syndromes (LR-MDS)

NCT05490446Myelodysplastic Syndromes

DrugTebapivat

Agios Pharmaceuticals, Inc.

Phase 2

Córdoba, Madrid, Salamanca, Seville

2022-11-07

Recruiting

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

NCT05253651Colorectal Neoplasms

DrugsTucatinib·Herceptin·Erbitux·Avastin

Seagen, a wholly owned subsidiary of Pfizer

Phase 3

400

L'Hospitalet de Llobregat, Barcelona, San Cristóbal de La Laguna, Alicante, Córdoba, Lleida, Madrid, Málaga

2022-10-24

Recruiting

Long-term Safety and Efficacy of GBG Study Participants

NCT05739591Breast Cancer

GBG Forschungs GmbH

Observational

400

Córdoba, Bilbao, Santa Cruz de Tenerife, Badalona, Barcelona, Lleida, Sabadell, Cáceres

2022-10-12

Active, closed

Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer

NCT05502237Non-small Cell Lung Cancer

DrugsDomvanalimab·Zimberelimab·Nab-paclitaxel·Pemetrexed

Gilead Sciences

Phase 3

1,021

Barcelona, Córdoba, Girona, Jaén, Las Palmas de Gran Canaria, Madrid, Majadahonda, Reus

2022-10-12

Active, closed

Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRα) Expressing, Platinum-sensitive Epithelial Ovarian Cancer

NCT05456685High Grade Ovarian Cancer, Primary Peritoneal Cancer, Fallopian Tube Cancer

DrugsMIRV·Mirvetuximab Soravtansine·Carboplatin

AbbVie

Phase 2

125

A Coruña, Badalona, Córdoba, Pamplona, Badajoz, Barcelona, Lleida, Madrid

2022-09-28

Active, closed

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma

NCT05409066Follicular Lymphoma (FL)

DrugsEpcoritamab·Lenalidomide·Rituximab

Genmab

Phase 3

549

Badalona, L'Hospitalet de Llobregat, Santander, Córdoba, Pamplona, Barcelona, Cáceres, Madrid

2022-09-20

Active, closed

A Phase III Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Non Small Cell Lung Cancer (NSCLC) Whose Disease Progressed On or After Prior Anti PD (L)1 Therapy And Platinum Based Chemotherapy

NCT05450692Advanced or Metastatic Non-Small Cell Lung Cancer

DrugsCeralasertib·Durvalumab·Docetaxel

AstraZeneca

Phase 3

594

A Coruña, Barcelona, Castellon, Córdoba, Hospitalet deLlobregat, Madrid, Málaga, Ourense

2022-09-15

Active, closed

A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

NCT05531565Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus

DrugLitifilimab

Biogen

Phase 2/3

450

Badalona, Valladolid, Castellon, Alcorcón, Majadahonda, A Coruña, Barcelona, Córdoba

2022-09-13

Recruiting

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

NCT05489211Endometrial Cancer, Gastric Cancer, Metastatic Castration-resistant Prostate Cancer, Ovarian Cancer

DrugsPrednisone/Prednisolone·Volrustomig·Rilvegostomig·Dato-DXd

AstraZeneca

Phase 2

454

Barcelona, Córdoba, Madrid, Málaga, Pamplona, Seville

2022-09-06

Recruiting

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

NCT05386108Breast Neoplasms, Brain Neoplasms, Neoplasms by Site, Neoplasms

DrugsElacestrant·Abemaciclib

Stemline Therapeutics, Inc.

Phase 1/2

Córdoba, Madrid, El Palmar, Barcelona, Pamplona, Santiago de Compostela, Valencia

2022-08-31

Active, closed

A Study to Learn About the Safety of Diranersen (BIIB080) Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age

NCT05399888Mild Cognitive Impairment Due to Alzheimer's Disease, Alzheimer's Disease Dementia

Biogen

Phase 2

416

Pamplona, Getxo, Barcelona, Córdoba, Lleida, Seville, Valencia

2022-08-24

Active, closed

A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)

NCT05327530Locally Advanced or Metastatic Urothelial Carcinoma

DrugsAvelumab·Sacituzumab Govitecan

EMD Serono Research & Development Institute, Inc.

Phase 2

256

Badajoz, Barcelona, Córdoba, Elche, Lugo, Madrid, Manresa

2022-08-17

Active, closed

A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer

NCT05388669Advanced or Metastatic Non-small Cell Lung Cancer

DrugsLazertinib·Amivantamab

Janssen Research & Development, LLC

Phase 3

418

A Coruña, Alicante, Barcelona, Córdoba, Las Palmas de Gran Canaria, Lugo, Madrid, Majadahonda

2022-08-05

Active, closed

Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome

NCT05349214Sjogren Syndrome

DrugIanalumab

Novartis Pharmaceuticals

Phase 3

506

Santander, Vigo, Barcelona, Córdoba, Madrid, Valencia

2022-08-04

Active, closed

Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01)

NCT05464030Colorectal Cancer

DrugsM9140·Folinic acid·Adrucil·Capecitabine

EMD Serono Research & Development Institute, Inc.

Phase 1

220

Barcelona, Córdoba, L'Hospitalet de Llobregat, Madrid, Santiago de Compostela, Seville

2022-08-04

Active, closed

A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

NCT05306340Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer

DrugsGiredestrant·Tamoxifen·Exemestane·Everolimus

Genentech, Inc.

Phase 3

373

A Coruña, Barcelona, Córdoba, Madrid, Murcia, Valencia

2022-08-03

Active, closed

Savolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment

NCT05261399Carcinoma, Non-Small-Cell Lung

DrugsSavolitinib·Tagrisso·Osimertinib·Pemetrexed

AstraZeneca

Phase 3

341

Badajoz, Badalona, Barcelona, Córdoba, Girona, Madrid, Majadahonda, Málaga

2022-08-03

Recruiting

Perpetual Observational Study - Ventilator Associated Pneumonia

NCT05719259Ventilator Associated Pneumonia

European Clinical Research Alliance for Infectious Diseases (ECRAID)

Observational

20,000

Córdoba, Oviedo, Burjassot, Barcelona

2022-08-03

Active, closed

Clinical Study of Fianlimab in Combination With Cemiplimab Versus Pembrolizumab in Adolescent and Adult Patients With Previously Untreated Unresectable Locally Advanced or Metastatic Melanoma

NCT05352672Melanoma

DrugsFianlimab·Cemiplimab·Keytruda·Pembrolizumab

Regeneron Pharmaceuticals

Phase 3

1,546

Córdoba, Badalona, Barcelona, Donostia / San Sebastian, El Palmar, Oviedo, A Coruña, Girona

2022-07-14

Active, closed

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events

NCT05360446Coronary Artery Disease

DrugInclisiran sodium

Novartis Pharmaceuticals

Phase 3

610

A Coruña, Barcelona, Córdoba, Madrid, Salamanca, Valencia

2022-07-08

Active, closed

Long Term Evaluation of Safety and Efficacy of Tildrakizumab in Patients With Psoriatic Arthritis

NCT04991116Psoriatic Arthritis

Sun Pharmaceutical Industries Limited

Phase 3

529

A Coruña, Córdoba, Málaga, Santiago de Compostela, Seville, Valencia

2022-06-30

Active, closed

Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

NCT04975997Multiple Myeloma

DrugsIberdomide·Bortezomib·Daratumumab·Dexamethasone

Celgene

Phase 3

939

Pamplona, Barcelona, Cáceres, Córdoba, Madrid, Málaga, Murcia, Oviedo

2022-06-23

Active, closed

Study of ctDNA as Prognostic Factor on Resectable Stage IIIA NSCLC Patients Treated With Neoadjuvant Treatment

NCT05382052Non Small Cell Lung Cancer Stage III, Neoadjuvant Treatment

Fundación GECP

Observational

100

A Coruña, Alicante, Badalona, Barcelona, Bilbao, Córdoba, Girona, Pamplona

2022-06-17

Active, closed

Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer

NCT05132075Non-Small Cell Lung Cancer

DrugsOpnurasib·Docetaxel

Novartis Pharmaceuticals

Phase 3

Pamplona, Oviedo, Córdoba, Madrid

2022-06-15

Recruiting

Spanish Academy of Dermatology and Venereology (AEDV) Melanoma Registry

NCT05673681Melanoma

Fundación Academia Española de Dermatología

Observational

7,000

Badalona, A Coruña, Barcelona, Córdoba, Las Palmas, León, Madrid, Oviedo

2022-06-01

Recruiting

A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB

NCT05183646FSGS

DrugRepagermanium

Dimerix Bioscience Pty Ltd

Phase 3

286

Almería, Barcelona, Córdoba, Madrid, Majadahonda, Seville

2022-05-30

Active, closed

A Study to Evaluate the Efficacy and Safety of Serplulimab in Combination With Chemotherapy and Concurrent Radiotherapy in Patients With Limited-Stage Small Cell Lung Cancer

NCT05353257Limited-Stage Small Cell Lung Cancer

DrugsCarboplatin/cisplatin-etoposide·Serplulimab

Shanghai Henlius Biotech

Phase 3

511

Badajoz, Badalona, Barcelona, Córdoba, Madrid, Seville, Valdecilla, Valencia

2022-05-17

Active, closed

Adjuvant Encorafenib and Binimetinib in High-risk Stage II Melanoma With a BRAF Mutation.

NCT05270044Melanoma

Pierre Fabre Medicament

Phase 3

815

Badalona, L'Hospitalet de Llobregat, El Palmar, Barcelona, Córdoba, Madrid, Málaga, Valencia

2022-05-02

Recruiting

Retrospective Prospective Multicentric Clinical Follow up of Patients After Being Treated With TricValve®

NCT05114850Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Insufficiency, Heart Failure

P+F Products + Features GmbH

Observational

450

Galdakao, Málaga, Barcelona, Córdoba, Lugo, Madrid, Oviedo, Salamanca

2022-04-20

Active, closed

Endometrial Cancer Patientes MMR Deficient Comparing Chemotherapy vs Dostarlimab in First Line

NCT05201547Endometrial Cancer

DrugsCarboplatin/Paclitaxel·Dostarlimab

ARCAGY/ GINECO GROUP

Phase 3

260

Elche, Badalona, Córdoba, León, Palma, Palma de Mallorca, Santiago de Compostela, Valencia

2022-04-15

Recruiting

Neoadjuvant and Adjuvant Treatment in Resectable Non-small Cell Lung Cancer

NCT05061550Non-small Cell Lung Cancer

DrugsAZD0171·Pemetrexed/Cisplatin·Pemetrexed/Carboplatin·Monalizumab

AstraZeneca

Phase 2

630

A Coruña, Alicante, Barcelona, Córdoba, Madrid, Majadahonda, Málaga, Reus

2022-04-14

Active, closed

Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer

NCT05316155Non-Muscle Invasive Bladder Neoplasms

DrugErdafitinib

Janssen Research & Development, LLC

Phase 1/2

235

Barcelona, Córdoba, Madrid, Valencia

2022-04-11

By invitation

Trial of Sibeprenlimab in the Treatment of Immunoglobulin A Nephropathy (IgAN)

NCT05248659Immunoglobulin A Nephropathy

DrugSibeprenlimab

Otsuka Pharmaceutical Development & Commercialization, Inc.

Phase 2/3

600

Barcelona, Córdoba, Ellenboro, Madrid, Seville

2022-04-05

Recruiting

Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease

NCT05312879Proteinuric Kidney Disease

Vertex Pharmaceuticals Incorporated

Phase 2/3

466

Barcelona, Córdoba, Madrid, Seville

2022-03-30

Active, closed

Evaluate Durvalumab and Tremelimumab +/- Lenvatinib in Combination With TACE in Patients With Locoregional HCC

NCT05301842Hepatocellular Carcinoma

DrugsTremelimumab·Lenvatinib·Durvalumab

AstraZeneca

Phase 3

760

Barcelona, Córdoba, Donostia / San Sebastian, Madrid

2022-03-28

Active, closed

Study of Capivasertib + Docetaxel vs Placebo + Docetaxel as Treatment for Metastatic Castration Resistant Prostate Cancer (mCRPC)

NCT05348577Prostate Cancer

DrugsCapivasertib·Docetaxel

AstraZeneca

Phase 3

1,035

Barcelona, Córdoba, Lugo, Madrid, Málaga, Sabadell, Seville

2022-03-25

Active, closed

Trial of Sibeprenlimab in the Treatment of A Nephropathy (IgAN)

NCT05248646Immunoglobulin A Nephropathy

DrugSibeprenlimab

Otsuka Pharmaceutical Development & Commercialization, Inc.

Phase 3

530

A Coruña, Barakaldo, Barcelona, Bilbao, Córdoba, Ferrol, Madrid, Santander

2022-03-15

Recruiting

Clinical Trial on HIPEC With Mitomycin C in Colon Cancer Peritoneal Metastases (GECOP-MMC)

NCT05250648Peritoneal Carcinomatosis, Colon Cancer

Hospital Universitario de Fuenlabrada

Phase 4

216

Elche, Almería, Badajoz, Sant Joan Despí, Castellon, Ciudad Real, Córdoba, San Sebastián

2022-03-02

Recruiting

Programme for Intervention in Paediatric Obesity

NCT06457412Obesity, Childhood

Maimónides Biomedical Research Institute of Córdoba

Not applicable

200

Córdoba

2022-03-01

Active, closed

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

NCT05211895Non-Small Cell Lung Cancer

DrugsDomvanalimab·Durvalumab

AstraZeneca

Phase 3

791

Bilbao (Vizcaya), Castellon, Córdoba, El Palmar, Palma de Mallorca, Sabadell (Barcelona)

2022-02-18

Recruiting

Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)

NCT05263206Pruritus

DrugsFexofenadine·Dupilumab

Sanofi

Phase 3

284

Barcelona, Pontevedra, Alicante, Córdoba

2022-02-15

Active, closed

Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease

NCT05202509Atherosclerotic Cardiovascular Disease

DrugObicetrapib

NewAmsterdam Pharma

Phase 3

9,541

A Coruña, Alicante, Almería, Barcelona, Córdoba, Granada, Madrid, Málaga

2022-02-07

Active, closed

Efficacy of a Combined ACT+ App Intervention to Improve Psychological Flexibility and Associated Symptoms in Cancer Patients

NCT05126823Cancer

Francisco Garcia Torres

Not applicable

120

Córdoba

2022-02-01

Active, closed

Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients

NCT05234190Rejection; Transplant, Liver, Liver Failure, Liver Diseases

Quell Therapeutics Limited

Phase 1/2

Barcelona, Córdoba, Madrid

2022-01-21

Active, closed

A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)

NCT05002127Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Gastric Adenocarcinoma

DrugsEvorpacept·Ramucirumab·Herceptin·Taxol

ALX Oncology Inc.

Phase 2/3

127

Alicante, Badalona, Barcelona, Córdoba, Lugo, Madrid, Santander, Zaragoza

2022-01-15

Active, closed

Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

NCT05407636AMD, nAMD, Wet Age-related Macular Degeneration, wAMD

DrugsEylea·Aflibercept

AbbVie

Phase 3

735

Santiago de Compostela, L'Hospitalet de Llobregat, Córdoba, Las Palmas de Gran Canaria, Majadahonda, Barcelona, Madrid

2022-01-13

Recruiting

National GMA Post-market Clinical Follow-up Study (GRACE)

NCT05636709Crohn Disease, Ulcerative Colitis

Adacyte Therapeutics SL

Observational

350

Albacete, Alicante, Badalona, Barcelona, Galdakao, Castellon, Cadiz, Córdoba

2022-01-11

Active, closed

Circulating Tumor DNA Based Decision for Adjuvant Treatment in Colon Cancer Stage II-III

NCT07821333Colorectal Neoplasms Malignant, Minimal Residual Disease, Circulating Tumor Cell

DrugsFolfoxiri·Folfox

Fundación para la Investigación del Hospital Clínico de Valencia

Phase 2

L'Hospitalet de Llobregat, Barcelona, Córdoba, Madrid, Valencia

2022-01-01

Active, closed

A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC)

NCT04819100Carcinoma, Non-Small-Cell Lung

DrugSelpercatinib

Eli Lilly and Company

Phase 3

152

Santiago de Compostela, Cadiz, Córdoba, Badalona, Barcelona, L'Hospitalet Del Llobregat, Mataró, León

2021-12-20

Recruiting

A Planned Study at Multiple Sites is Being Done to Compare the Results of Two Types of Trifocal Toric Intraocular Lenses Used in Cataract Surgery

NCT07232615Presbyopia Correction, Astigmatism, Cataract

Biotech Healthcare Holding Gmbh

Not applicable

138

Córdoba

2021-11-22

Active, closed

Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

NCT04994717Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)

DrugBlinatumomab

Amgen

Phase 3

303

Córdoba, Seville, Santander, Salamanca, Badalona, Barcelona, L'Hospitalet de Llobregat, Valencia

2021-11-02

Active, closed

Savolitinib Plus Durvalumab Versus Sunitinib and Durvalumab Monotherapy in MET-Driven, Unresectable and Locally Advanced or Metastatic PRCC

NCT05043090Papillary Renal Cell Carcinoma

DrugsSavolitinib·Sunitinib·Durvalumab

AstraZeneca

Phase 3

148

A Coruña, Barcelona, Córdoba, Madrid, Majadahonda, Málaga, Pamplona, Seville

2021-10-28

Recruiting

FGF23 and Cardiovascular Damage in Anemia With an Without Chronic Kidney Disease.

NCT05356325Fibroblast Growth Factor 23, Anemia, CKD

Maimónides Biomedical Research Institute of Córdoba

Observational

401

Córdoba

2021-10-18

Recruiting

Spanish Registry of Patients With IgM Monoclonal Gammopathies

NCT05093153Waldenstrom Macroglobulinemia

Fundación Española de Hematología y Hemoterapía

Observational

1,000

Mérida, Palma, Palma de Mallorca, Badalona, Barcelona, Manresa, Sabadell, Córdoba

2021-10-01

Active, closed

A Study to Evaluate Chemotherapy Plus Osimertinib Against Chemotherapy Plus Placebo in Patients With Non-small Cell Lung Cancer (NSCLC)

NCT04765059Non-small Cell Lung Cancer

DrugCarboplatin

AstraZeneca

Phase 3

Alicante, Barcelona, Córdoba, León, Madrid, Málaga, Murcia, Oviedo

2021-09-12

Active, closed

A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease

NCT04929210Arthritis, Psoriatic

DrugsTremfya·Guselkumab

Janssen Research & Development, LLC

Phase 4

411

A Coruña, Barakaldo, Barcelona, Bilbao, Córdoba, Madrid, Málaga, Sabadell

2021-08-30

Active, closed

A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice

NCT05049798Arthritis, Psoriatic

DrugsIL-17i·Tremfya·Guselkumab

Janssen Pharmaceutica N.V., Belgium

Observational

1,314

A Coruña, Algeciras / Cadiz, Barcelona, Bilbao, Córdoba, Granada, Madrid, Oviedo

2021-08-25

By invitation

Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

NCT04957719Acute Myocardial Infarction

Viatris Innovation GmbH

Phase 3

25,000

Almería, Badalona, Barcelona, Boadilla del Monte, Córdoba, El Palmar, Fuencarral-El Pardo, Huelva

2021-08-14

Active, closed

Chemotherapy-Free pCR-Guided Strategy With Trastuzumab-pertuzumab and T-DM1 in HER2-positive Early Breast Cancer

NCT04733118Early Breast Cancer

MedSIR

Phase 2

393

L'Hospitalet de Llobregat, Córdoba, Reus, A Coruña, Alicante, Badalona, Barcelona, Bilbao

2021-08-05

Active, closed

A Study of the Efficacy, Safety, and Pharmacokinetics of a 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)

NCT04657289Neovascular Age-related Macular Degeneration (nAMD)

DrugRanibizumab

Hoffmann-La Roche

Phase 3

451

L'Hospitalet de Llobregat, San Cugat Del Valles, Majadahonda, Pamplona, Oviedo, Barcelona, Córdoba, Madrid

2021-07-14

Active, closed

A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs

NCT04908202Psoriatic Arthritis

DrugDeucravacitinib

Bristol-Myers Squibb

Phase 3

670

A Coruña, Córdoba, Madrid, Sabadell

2021-07-13

Active, closed

Efficacy and Safety Comparison of Niraparib to Placebo in Participants With Human Epidermal Growth Factor 2 Negative (HER2-) Breast Cancer Susceptibility Gene Mutation (BRCAmut) or Triple-Negative Breast Cancer (TNBC) With Molecular Disease

NCT04915755Neoplasms, Breast

DrugNiraparib

GlaxoSmithKline

Phase 3

Barcelona, Cáceres, Córdoba, Granada, Madrid, Málaga, Santiago de Compostela, Valencia

2021-06-28

Active, closed

Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10)

NCT04793958Advanced Colorectal Cancer, Metastatic Colorectal Cancer

DrugsAdagrasib·MFOLFOX6·Erbitux·Folfox

Mirati Therapeutics Inc.

Phase 3

461

A Coruña, Badalona, Barcelona, Córdoba, LHospitalet de Llobregat, Madrid, Pamplona, Sabadell

2021-06-24

Active, closed

A Study of Guselkumab in Participants With Active Psoriatic Arthritis

NCT04882098Arthritis, Psoriatic

DrugGuselkumab

Janssen Research & Development, LLC

Phase 3

1,054

A Coruña, Córdoba, Madrid, Málaga, Móstoles, Murcia, San Sebastián de los Reyes, Santiago de Compostela

2021-06-17

By invitation

Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting

NCT04451044Coronary Artery Disease, Ischemic Heart Disease

Philips Clinical & Medical Affairs Global

Not applicable

3,212

Córdoba, León, Madrid, Santander

2021-06-17

Recruiting

Inmobilization With Compression Bandage vs Antebraquial Splint in Distal Radius Fractures

NCT06019585Distal Radius Fractures, Internal Fixation; Complications, Mechanical

Hospital Costa del Sol

Not applicable

120

Córdoba, Málaga

2021-06-01

Recruiting

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

NCT04844606Ulcerative Colitis, Ulcerative Colitis Chronic, Inflammatory Bowel Diseases, Crohn's Disease

DrugMirikizumab

Eli Lilly and Company

Phase 3

150

Córdoba, Esplugues de Llobregat, Sabadell, Valencia

2021-05-26

Active, closed

Prospective Observational Study of Filgotinib in Subjects With Rheumatoid Arthritis

NCT04871919Rheumatoid Arthritis

DrugFilgotinib

Alfasigma S.p.A.

Observational

1,304

A Coruña, Barcelona, Córdoba, Mérida, Murcia, Palma, Pontevedra, Santa Cruz de Tenerife

2021-05-11

Recruiting

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

NCT04614103Metastatic Non Small Cell Lung Cancer

DrugLifileucel

Iovance Biotherapeutics, Inc.

Phase 2

170

A Coruña, Barcelona, Córdoba, Madrid, Málaga, Pamplona, Salamanca, Seville

2021-05-07

Active, closed

A Study of Atezolizumab Versus Placebo as Adjuvant Therapy in Participants With High-risk Muscle-invasive Bladder Cancer (MIBC) Who Are ctDNA Positive Following Cystectomy

NCT04660344Muscle-invasive Bladder Cancer

DrugsTecentriq·Atezolizumab

Hoffmann-La Roche

Phase 3

761

Sabadell, Santander, Córdoba, Donostia / San Sebastian, Barcelona, Madrid, Seville, Valencia

2021-05-03

Active, closed

A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab

NCT04770896Unresectable Hepatocellular Carcinoma

DrugsSorafenib·Tecentriq·Lenvatinib·Atezolizumab

Hoffmann-La Roche

Phase 3

557

Palma de Mallorca, Santiago de Compostela, Pamplona/iruña, Córdoba, Madrid, Valencia, Zaragoza

2021-04-26

Recruiting

Fast Track Therapeutic Model in Acute Complicated Appendicitis in Pediatrics

NCT05761080Laparoscopic Appendectomy, Complicated Appendicitis, Periappendicular Abscess

DrugMaximum

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Phase 4

772

Barcelona, Córdoba, Lleida, Madrid, Seville, Badalona, Esplugues de Llobregat, Girona

2021-04-22

Active, closed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Fuzuloparib Combined With Abiraterone Acetate and Prednisone (AA-P) Versus Placebo Combined With AA-P as First-Line Treatment in Patients With Metastatic Castration-Resistant Prostate Cancer

NCT04691804Metastatic Castration-Resistant Prostate Cancer (mCRPC)

DrugFluzoparib

Jiangsu HengRui Medicine Co., Ltd.

Phase 3

496

Castellon, Barcelona, Córdoba, Girona, Madrid, Málaga, Seville, Valencia

2021-03-18

Active, closed

A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer

NCT04486378Colorectal Cancer Stage II, Colorectal Cancer Stage III

DrugAutogene cevumeran

BioNTech SE

Phase 2

327

A Coruña, Ávila, Badalona, Barcelona, Córdoba, Madrid, Majadahonda, Málaga

2021-03-08

Active, closed

Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation

NCT04685135Metastatic Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer

DrugsAdagrasib·Taxotere·Docetaxel

Mirati Therapeutics Inc.

Phase 3

453

Pamplona, A Coruña, Alicante, Badalona, Barakaldo, Barcelona, Córdoba, Girona

2021-02-23

Active, closed

Galinpepimut-S Versus Investigator's Choice of Best Available Therapy for Maintenance in AML CR2/CRp2

NCT04229979Acute Myeloid Leukemia

DrugsGm-Csf·Sargramostim·Ara-C·Decitabine

Sellas Life Sciences Group

Phase 3

127

Cáceres, Córdoba, Madrid, Oviedo, Pamplona, Salamanca, Seville, Valencia

2021-02-08

Recruiting

Unified Barlow Protocol (UP) in Cancer Survivors for Cognitive Impairments

NCT05289258Cancer, Breast

Universidad de Córdoba

Not applicable

123

Córdoba

2021-01-25

Active, closed

A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma

NCT04657991Melanoma

DrugsBinimetinib·Encorafenib·Keytruda·Pembrolizumab

Pfizer

Phase 3

257

Badalona, Santander, Majadahonda, El Palmar, A Coruña, Barcelona, Córdoba, Jaén

2021-01-15

Active, closed

A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)

NCT04628494Diffuse Large B-cell Lymphoma

DrugEpcoritamab

Genmab

Phase 3

483

Badalona, Barcelona, Cadiz, Cáceres, Córdoba, Lleida, Madrid, Salamanca

2021-01-13

Active, closed

Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)

NCT04634877Endometrial Neoplasms

DrugsDocetaxel·Keytruda·Paclitaxel·Cisplatin

Merck Sharp & Dohme LLC

Phase 3

990

Girona, Madrid, Barcelona, Córdoba

2021-01-10

Active, closed

A Study of Avutometinib (VS-6766) v. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer With and Without a KRAS Mutation

NCT04625270Low Grade Ovarian Serous Adenocarcinoma, Ovarian Cancer

DrugsAvutometinib (VS-6766) and defactinib·Avutometinib·Lumakras

Verastem, Inc.

Phase 2

225

Barcelona, Córdoba, Madrid, Valencia

2020-12-21

Active, closed

Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-small Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy

NCT04655976Lung Cancer, Non-Small Cell

DrugsCobolimab·Dostarlimab·Docetaxel

GlaxoSmithKline

Phase 2/3

758

A Coruña, Badalona, Barcelona, Burgos, Córdoba, Las Palmas de Gran Canar, Madrid, Málaga

2020-12-08

Recruiting

LANDMARK Trial: a Randomised Controlled Trial of Myval THV

NCT04275726Aortic Valve Stenosis

Meril Life Sciences Pvt. Ltd.

Not applicable

988

Palma de Mallorca, Las Palmas, Córdoba, Madrid, Valladolid

2020-11-04

Active, closed

Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer

NCT04464226Cancer

DrugDarolutamide

Bayer

Phase 3

402

Elche, Manacor, Palma de Mallorca, Sabadell, Alcorcón, Barcelona, Cáceres, Córdoba

2020-10-20

Active, closed

Study of Durvalumab Versus Placebo in Combination With Definitive Chemoradiation Therapy in Patient With ESCC

NCT04550260Esophageal Squamous Cell Carcinoma

DrugsFluorouracil·Durvalumab·Capecitabine·Cisplatin

AstraZeneca

Phase 3

640

Barcelona, Córdoba, Madrid, Pamplona, Santander, Zaragoza

2020-10-19

Active, closed

Myasthenia Gravis Inebilizumab Trial

NCT04524273Myasthenia Gravis

DrugInebilizumab

Amgen

Phase 3

238

Badalona, Barcelona, Córdoba

2020-10-15

Active, closed

Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome

NCT04401748Myelodysplastic Syndrome (MDS)

DrugsVenclexta·Azacitidine·Venetoclax

AbbVie

Phase 3

531

Badalona, Córdoba, Pozuelo de Alarcón, Barcelona, Madrid, Salamanca, Seville, Valencia

2020-09-10

Active, closed

A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors

NCT04482309Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer, Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer

DrugTrastuzumab deruxtecan

AstraZeneca

Phase 2

477

Barcelona, Córdoba, Madrid, Valencia

2020-08-18

Active, closed

A Study to Evaluate MEDI5752 and Axitinib in Subjects With Advanced Renal Cell Carcinoma

NCT04522323Advanced Renal Cell Carcinoma

DrugsVolrustomig·Axitinib·Lenvatinib

MedImmune LLC

Phase 1

Barcelona, Córdoba, Madrid, Sabadell, Seville, Valencia

2020-08-05

Active, closed

Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib

NCT04421963Ovarian Cancer, Breast Cancer

DrugOlaparib

AstraZeneca

Phase 3

185

Badalona, Barcelona, Córdoba, Donostia / San Sebastian, Granada, Madrid, Pamplona, Valencia

2020-08-04

Active, closed

Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer

NCT04494425Advanced or Metastatic Breast Cancer

DrugsTrastuzumab deruxtecan·Nab-paclitaxel·Capecitabine·Paclitaxel

AstraZeneca

Phase 3

866

A Coruña, Barcelona, Córdoba, El Palmar, Madrid, San Sebastián, Seville, Valencia

2020-07-24

Active, closed

Efficacy and Safety of Tildrakizumab Compared to Placebo in Anti-TNF naïve Subjects With Active Psoriatic Arthritis II (INSPIRE 2)

NCT04314531Active Psoriatic Arthritis

Sun Pharmaceutical Industries Limited

Phase 3

296

A Coruña, Córdoba, Madrid, Seville

2020-07-01

Recruiting

Spanish Registry of Esophagogastric Cancer

NCT04958720Esophageal Cancer, Gastric Cancer

Fundación Sociedad Española de Oncologia Médica

Observational

10,000

Alicante, Elche, Elda, Córdoba, Málaga, Seville, Palma de Mallorca, Barcelona

2020-04-27

Active, closed

Capivasertib+Fulvestrant vs Placebo+Fulvestrant as Treatment for Locally Advanced (Inoperable) or Metastatic HR+/HER2- Breast Cancer

NCT04305496Locally Advanced (Inoperable) or Metastatic Breast Cancer

DrugsCapivasertib·Fulvestrant

AstraZeneca

Phase 3

818

A Coruña, Barcelona, Córdoba, Hosp de Llobregat(Barcelona), Jaén, La Laguna (Tenerife), Lleida, Madrid

2020-04-16

Active, closed

Enfortumab Vedotin and Pembrolizumab vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

NCT04223856Urothelial Cancer

DrugsEnfortumab Vedotin·Keytruda·Gemcitabine·Cisplatin

Astellas Pharma Global Development, Inc.

Phase 3

886

Barcelona, Córdoba, Lugo, Madrid, Manresa, Pamplona, Sabadell, Santander

2020-03-30

Active, closed

TAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations

NCT04129502Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

DrugsMobocertinib·Pemetrexed·Cisplatin·Carboplatin

Takeda

Phase 3

354

L'Hospitalet de Llobregat, A Coruña, Alicante, Barcelona, Córdoba, Madrid, Valencia

2020-01-10

Active, closed

LAM561 With RT and TMZ for Adults With Glioblastoma

NCT04250922Primary Glioblastoma, Glioblastoma Multiforme

DrugLAM561

Laminar Pharmaceuticals

Phase 2/3

144

Córdoba, Seville, Barcelona, Madrid, Valencia, Sabadell

2019-12-01

Active, closed

Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors

NCT04041310Solid Tumor, Adult

DrugsKeytruda·Pembrolizumab

Nouscom SRL

Phase 1/2

115

A Coruña, Barcelona, Córdoba, Granada, Madrid, Pamplona, Salamanca, Santander

2019-10-21

Active, closed

A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis

NCT03958877Multiple Sclerosis, Relapsing-Remitting

DrugsPlegridy·Avonex

Biogen

Phase 3

152

Esplugues de Llobregat, El Palmar, Córdoba, Madrid

2019-10-18

Active, closed

A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer

NCT03975647HER2-positive Breast Cancer

DrugsTucatinib·Trastuzumab emtansine

Seagen, a wholly owned subsidiary of Pfizer

Phase 3

466

Palma de Mallorca, Barcelona, San Cristóbal de La Laguna, Córdoba, Madrid, Sant Joan Despí, Seville, Valencia

2019-10-02

Active, closed

Safety and Efficacy of AT-001 in Patients With Diabetic Cardiomyopathy

NCT04083339Diabetic Cardiomyopathies

Applied Therapeutics, Inc.

Phase 3

675

Badalona, El Palmar, A Coruña, Barcelona, Córdoba, Seville, Valencia

2019-09-20

Active, closed

Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia

NCT04119050Warm Autoimmune Hemolytic Anemia

DrugNipocalimab

Janssen Research & Development, LLC

Phase 2/3

118

Alcalá de Henares, Badalona, Barcelona, Burgos, Córdoba, Las Palmas de Gran Canaria, Madrid, Majadahonda

2019-08-15

Recruiting

Cardiovascular Prevention Strategies in Elderly Patients With Cancer (CARTIER Clinical Trial)

NCT03711110Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma), Elderly, Antineoplastic Agents, Cardiotoxicity

Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León

Not applicable

514

Santiago de Compostela, Galdakao, Barcelona, Córdoba, Madrid, Málaga, Salamanca, Seville

2019-08-02

Active, closed

A Study of Cusatuzumab Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia Who Are Not Candidates for Intensive Chemotherapy

NCT04023526Leukemia, Myeloid, Acute

DrugsCusatuzumab·Azacitidine

OncoVerity, Inc.

Phase 2

103

Pozuelo de Alarcón, Barcelona, Córdoba, Madrid, Palma, Salamanca, Valencia

2019-07-29

Active, closed

Phase I/II Study of Rapcabtagene Autoleucel in CLL, 3L+ DLBCL, r/r ALL and 1L HR LBCL

NCT03960840Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Diffuse Large B-cell Lymphoma, Acute Lymphoblastic Leukemia

DrugIbrutinib

Novartis Pharmaceuticals

Phase 1/2

217

Badalona, L'Hospitalet de Llobregat, Barcelona, Córdoba, Madrid, Salamanca, Seville, Valencia

2019-06-26

Active, closed

Study of Cabozantinib in Combination With Nivolumab and Ipilimumab in Patients With Previously Untreated Advanced or Metastatic Renal Cell Carcinoma

NCT03937219Renal Cell Carcinoma

DrugsCabozantinib·Yervoy·Ipilimumab·Opdivo

Exelixis

Phase 3

855

Santiago de Compostela, Pamplona, Barcelona, Córdoba, Madrid, Oviedo, Valencia

2019-06-25

Recruiting

E²-RADIatE: EORTC-ESTRO RADiotherapy InfrAstrucTure for Europe

NCT03818503Cancer

European Organisation for Research and Treatment of Cancer - EORTC

Observational

2,000

Badalona, Barcelona, Cartagena, Córdoba, Madrid, Pamplona, Salamanca, Terrassa

2019-06-24

Active, closed

A Study of Nivolumab Combined With Ipilimumab Versus Nivolumab Alone in Participants With Advanced Kidney Cancer

NCT03873402Renal Cell Carcinoma

DrugsYervoy·Ipilimumab·Opdivo·Nivolumab

Bristol-Myers Squibb

Phase 3

437

Barcelona, Córdoba, Madrid, Pamplona, Sabadell, Santander, Santiago Compostela, Seville

2019-06-21

Active, closed

Childhood Obesity Risk Assessment Longitudinal Study

NCT06317883Child Obesity

Consorcio Centro de Investigación Biomédica en Red (CIBER)

Observational

1,508

Santiago de Compostela, Pamplona, Barcelona, Córdoba, Granada, Tarragona, Valencia, Zaragoza

2019-05-27

Recruiting

Safety of IBD Drugs During Pregnancy and Breastfeeding: Mothers and Babies' Outcomes (DUMBO Registry)

NCT03894228Inflammatory Bowel Diseases, Pregnancy

Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa

Observational

1,750

Santiago de Compostela, Córdoba, Granada, Huelva, Málaga, Seville, Huesca, Zaragoza

2019-05-21

Active, closed

NADIM II: Neo-Adjuvant Immunotherapy

NCT03838159Non Small Cell Lung Cancer

DrugsParaplatin·Taxol·Opdivo·Nivolumab

Fundación GECP

Phase 2

Alicante, Badalona, Barcelona, L'Hospitalet de Llobregat, Córdoba, Girona, Las Palmas de Gran Canaria, A Coruña

2019-05-15

Active, closed

A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease

NCT03887455Early Alzheimer's Disease

DrugLecanemab

Eisai Inc.

Phase 3

1,906

Sant Cugat del Vallès, Getxo, Donostia / San Sebastian, Barcelona, Córdoba, Madrid, Salamanca, Seville

2019-03-27

Active, closed

Phase III Study in First-line Treatment of Patients With Metastatic Colorectal Cancer Who Are Not Candidate for Intensive Therapy.

NCT03869892Metastatic Colorectal Cancer

DrugsTrifluridine/Tipiracil·Capecitabine

Institut de Recherches Internationales Servier

Phase 3

856

Alicante, Badalona, Barcelona, Córdoba, L'Hospitalet de Llobregat, Madrid, Santander, Seville

2019-03-21

Active, closed

A Study of Zolbetuximab (IMAB362) in Adults With Pancreatic Cancer

NCT03816163Pancreatic Cancer, Metastatic Pancreatic Cancer, Metastatic Pancreatic Adenocarcinoma

DrugsZolbetuximab·Nab-paclitaxel·Gemcitabine

Astellas Pharma Global Development, Inc.

Phase 2

393

Llobregat, Pamplona, Barcelona, Cáceres, Córdoba, Lleida, Madrid, Málaga

2019-03-15

Active, closed

Osimertinib Plus Savolitinib in EGFRm+/MET+ NSCLC Following Prior Osimertinib

NCT03778229Carcinoma

DrugsSavolitinib·Osimertinib

AstraZeneca

Phase 2

367

Córdoba, Donostia / San Sebastian, Madrid, Málaga, Valencia, Zaragoza

2019-01-09

Active, closed

Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients

NCT03737643Advanced Ovarian Cancer

DrugsOlaparib·Durvalumab·Paclitaxel·Bevacizumab

AstraZeneca

Phase 3

1,407

Córdoba, Madrid, Terrassa(Barcelona), Vigo

2019-01-04

Active, closed

A Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma

NCT03778957Hepatocellular Carcinoma

DrugsAvastin·Durvalumab·Bevacizumab

AstraZeneca

Phase 3

724

Córdoba, Madrid, Pamplona, San Sebastián(Guipuzcoa)

2018-11-30

Active, closed

Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC

NCT03732677Muscle Invasive Bladder Cancer

DrugsDurvalumab·Gemcitabine·Cisplatin

AstraZeneca

Phase 3

1,063

Badalona, Barcelona, Córdoba, Las Palmas de Gran Canaria, Madrid, Santander, Seville

2018-11-16

Active, closed

Treatment for Elderly Fit Newly Diagnosed Multiple Myeloma Patients Aged Between 65 and 80 Years

NCT03742297Newly Diagnosed Multiple Myeloma

DrugsMelphalan·Carfilzomib·Bortezomib·Daratumumab

PETHEMA Foundation

Phase 3

462

A Coruña, Albacete, Alicante, Badalona, Barcelona, Bilbao, Cáceres, Córdoba

2018-10-22

Recruiting

Extension Study for the Port Delivery System With Ranibizumab (Portal)

NCT03683251Neovascular Age-Related Macular Degeneration

DrugPDS Implant with Ranibizumab

Hoffmann-La Roche

Phase 3

1,000

L'Hospitalet de Llobregat, San Cugat Del Valles, Majadahonda, Pamplona, Oviedo, Burjassot, Barcelona, Córdoba

2018-09-20

Active, closed

A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Colitis

NCT03398135Ulcerative Colitis (UC)

DrugsSkyrizi·Risankizumab

AbbVie

Phase 3

1,242

Ferrol, Sabadell, Majadahonda, Vigo, Gijón, Barcelona, Córdoba, Madrid

2018-08-28

Active, closed

Study of Abexinostat in Patients With Relapsed or Refractory Follicular Lymphoma

NCT03600441Follicular Lymphoma

DrugAbexinostat

Xynomic Pharmaceuticals, Inc.

Phase 2

139

Donostia / San Sebastian, Barcelona, Córdoba, Madrid

2018-08-27

Active, closed

Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

NCT03547973Metastatic Urothelial Cancer

DrugsDomvanalimab·Zimberelimab·Avelumab·Enfortumab Vedotin

Gilead Sciences

Phase 2

502

Badalona, Barcelona, Córdoba, Las Palmas, Madrid, Majadahonda, Manresa, Ourense

2018-08-13

Recruiting

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

NCT03435796Neoplasms

Celgene

Phase 2/3

1,541

Barcelona, Córdoba, Esplugues de Llobregat, Madrid, Málaga, Pamplona, Salamanca, Santander

2018-07-19

Active, closed

A Study of Nivolumab in Participants With Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative Hepatic Resection or Ablation

NCT03383458Hepatocellular Carcinoma, Liver Cancer

DrugsOpdivo·Nivolumab

Bristol-Myers Squibb

Phase 3

545

Barcelona, Córdoba, Donostia / San Sebastian, Madrid, Pamplona, Sabadell (Barcelona), Seville, Valencia

2018-04-18

Active, closed

A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

NCT03466411Crohn's Disease

DrugsGuselkumab 1·Guselkumab 2·Guselkumab 3·Ustekinumab

Janssen Research & Development, LLC

Phase 2/3

1,409

Córdoba, Ferrol, Girona, Huelva, Madrid, Oviedo, Pontevedra, Seville

2018-04-13

Active, closed

A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations

NCT03390504Urothelial Cancer

DrugsVinflunine·Erdafitinib·Docetaxel·Pembrolizumab

Janssen Research & Development, LLC

Phase 3

629

Badajoz, Badalona, Barcelona, Cáceres, Córdoba, Granada, Jaén, Las Palmas de Gran Canaria

2018-03-23

Recruiting

MEditerranean LIfestyle in Pediatric Obesity Prevention

NCT04597281Obesity, Childhood

Luis A. Moreno Aznar

Not applicable

738

Córdoba, Santiago de Compostela, Zaragoza

2018-03-01

Active, closed

Efficacy, Safety and Tolerability Study of Long-acting Cabotegravir Plus Long-acting Rilpivirine (CAB LA + RPV LA) in Human-immunodeficiency Virus-1 (HIV-1) Infected Adults

NCT03299049HIV Infections

DrugsRilpivirine·Cabotegravir

ViiV Healthcare

Phase 3

1,049

Badalona, Barcelona, Córdoba, Elche Alicante, Madrid, Málaga, Santiago de Compostela, Seville

2017-10-27

Active, closed

Trial Comparing Irradiation Plus Long Term Adjuvant Androgen Deprivation With GnRH Antagonist Versus GnRH Agonist Plus Flare Protection in Patients With Very High Risk Localized or Locally Advanced Prostate Cancer

NCT02799706Prostate Cancer

DrugDegarelix

European Organisation for Research and Treatment of Cancer - EORTC

Phase 3

885

Alcorcón, Barcelona, Bilbao, Cartagena, Córdoba, Las Palmas de Gran Canaria, Pamplona, Sabadell

2017-09-25

Active, closed

A Study in Participants Previously Enrolled in a Genentech- and/or F. Hoffmann-La Roche Ltd-Sponsored Atezolizumab Study (IMbrella A)

NCT03148418Cancer

DrugsTecentriq·Avastin·Atezolizumab·Bevacizumab

Hoffmann-La Roche

Phase 3

382

Palma de Mallorca, Córdoba, A Coruña, Las Palmas de Gran Canaria, Pamplona, Barcelona, Cáceres, Jaén

2017-09-20

Active, closed

Paediatric Hepatic International Tumour Trial

NCT03017326Hepatoblastoma, Carcinoma, Hepatocellular

Drugs5Fluorouracil·Sorafenib·Vincristine·Doxorubicin

University of Birmingham

Phase 3

450

Córdoba

2017-08-24

Active, closed

Endocrine Therapy With or Without Abemaciclib (LY2835219) Following Surgery in Participants With Breast Cancer

NCT03155997Breast Cancer

DrugAbemaciclib

Eli Lilly and Company

Phase 3

5,637

Córdoba, Barcelona, Santiago de Compostela, Lleida, Pozuelo de Alarcón, Alcorcón, Madrid, Málaga

2017-07-12

Active, closed

A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC)

NCT03006068Ulcerative Colitis (UC)

DrugUpadacitinib

AbbVie

Phase 3

950

A Coruña, Santiago de Compostela, Santander, Las Palmas de Gran Canaria, Barcelona, Córdoba, Madrid, Salamanca

2017-01-31

Active, closed

An Observational Prospective Long-term Exposure Registry of Adult Patients With Moderate-to-Severe Ulcerative Colitis

NCT02808780Ulcerative Colitis

Janssen Biotech, Inc.

Observational

535

A Coruña, Barcelona, Córdoba, Fuenlabrada, Huelva, Madrid, Majadahonda, San Sebastián de los Reyes

2016-12-16

Active, closed

Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme

NCT02685605Glioblastoma

DrugTemozolomide

Universitätsmedizin Mannheim

Phase 3

314

Barcelona, Córdoba

2016-12-09

Active, closed

Study Evaluating the Efficacy, Safety, and Tolerability of Switching to Long-acting Cabotegravir Plus Long-acting Rilpivirine From Current Antiretroviral Regimen in Virologically Suppressed HIV-1-infected Adults

NCT02951052Infection, Human Immunodeficiency Virus, HIV Infections

Drugs2 NRTIs·Cabotegravir (CAB)·Rilpivirine (RPV)·Rilpivirine

ViiV Healthcare

Phase 3

618

Badalona, Barcelona, Córdoba, Elche Alicante, Madrid, Málaga, Santiago de Compostela, Seville

2016-10-28

Active, closed

Lenvatinib/Everolimus or Lenvatinib/Pembrolizumab Versus Sunitinib Alone as Treatment of Advanced Renal Cell Carcinoma

NCT02811861Renal Cell Carcinoma

DrugsSunitinib·Everolimus·Lenvatinib·Pembrolizumab

Eisai Inc.

Phase 3

1,069

Santander, Barcelona, Cáceres, Córdoba, Madrid, Oviedo, Seville, Valencia

2016-10-13

Active, closed

A Study of Niraparib (GSK3985771) Maintenance Treatment in Participants With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy

NCT02655016Ovarian Neoplasms

DrugNiraparib

Tesaro, Inc.

Phase 3

733

Badalona, Barcelona, Córdoba, Donostia / San Sebastian, Elche Alicante, Girona, Madrid, Seville

2016-07-11

Recruiting

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

NCT02735707Community-acquired Pneumonia, Influenza, COVID-19

DrugsConvalescent plasma·Repagermanium·Ivermectin·Telmisartan

UMC Utrecht

Phase 3

20,000

Barcelona, Cadiz, Córdoba, Madrid, Málaga, Ourense, Santander, Tortosa

2016-04-11

Active, closed

A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Adults With Rheumatoid Arthritis Who Are on a Stable Dose of Methotrexate and Who Have an Inadequate Response to Methotrexate

NCT02629159Rheumatoid Arthritis

DrugsHumira·Adalimumab·Upadacitinib

AbbVie

Phase 3

1,629

Santander, A Coruña, Córdoba, Santiago de Compostela

2015-12-01

Active, closed

A Study of Apalutamide (JNJ-56021927, ARN-509) Plus Androgen Deprivation Therapy (ADT) Versus ADT in Participants With mHSPC

NCT02489318Prostate Cancer

DrugApalutamide

Aragon Pharmaceuticals, Inc.

Phase 3

1,052

Barcelona, Córdoba, Jerez de la Frontera, Madrid, Pamplona

2015-11-27

Active, closed

A Study of Durvalumab or Tremelimumab Monotherapy, or Durvalumab in Combination With Tremelimumab or Bevacizumab in Advanced Hepatocellular Carcinoma

NCT02519348Hepatocellular Carcinoma

DrugsTremelimumab·Durvalumab·Bevacizumab

MedImmune LLC

Phase 2

433

Barcelona, Córdoba, Pamplona

2015-10-19

Active, closed

PALbociclib CoLlaborative Adjuvant Study

NCT02513394Breast Cancer

DrugPalbociclib

Alliance Foundation Trials, LLC.

Phase 3

5,796

A Coruña, Alicante, Badalona, Barcelona, Burgos, Castellon, Cáceres, Córdoba

2015-08

Active, closed

An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC)

NCT02257736Prostatic Neoplasms

DrugsZytiga·Apalutamide·Abiraterone acetate·Prednisone

Aragon Pharmaceuticals, Inc.

Phase 3

982

Alcorcón, Barcelona, Cadiz, Córdoba, Madrid, San Sebastián de los Reyes, Valencia

2014-11-26

Active, closed

Olaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer

NCT02032823Breast Cancer

DrugOlaparib

AstraZeneca

Phase 3

1,837

A Coruña, Ávila, Badajoz, Badalona, Barcelona, Castellon, Cáceres, Córdoba

2014-04-22

Active, closed

Olaparib Treatment in BRCA Mutated Ovarian Cancer Patients After Complete or Partial Response to Platinum Chemotherapy

NCT01874353Platinum Sensitive, BRCA Mutated, Relapsed Ovarian Cancer, Following Complete or Partial Response to Platinum Based Chemotherapy

DrugOlaparib

AstraZeneca

Phase 3

327

Barcelona, Córdoba, Girona, Madrid, Pamplona, Valencia

2013-09-03

Active, closed

Olaparib Maintenance Monotherapy in Patients With BRCA Mutated Ovarian Cancer Following First Line Platinum Based Chemotherapy.

NCT01844986Newly Diagnosed, Advanced Ovarian Cancer, FIGO Stage III-IV, BRCA Mutation

DrugOlaparib

AstraZeneca

Phase 3

450

Barcelona, Córdoba, Hospitalet deLlobregat(Barcelo, Madrid, Valencia

2013-08-26

Recruiting

Product Surveillance Registry

NCT01524276Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders

Medtronic

Observational

100,000

A Coruña, Córdoba, Elche, Girona, Granada, L'Hospitalet de Llobregat, Madrid, Málaga

2012-01

Recruiting

Assessment of Transcatheter Edge-to-Edge Repair in Atrial Functional Mitral Regurgitation (ATRIAL-MR)

NCT06911099Atrial Functional Mitral Regurgitation, Mitral Insufficiency

University Hospital of Cologne

Observational

1,000

Barcelona, Córdoba, León, Oviedo, Vigo

2010-01-01

Recruiting

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

NCT00271180Arrhythmia, Bradycardia, Heart Failure, Sinus Tachycardia

Medtronic

Observational

20,000

A Coruña, Barcelona, Córdoba, Girona, Granada, Madrid, Palma de Mallorca, Salamanca

1983-01

Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Spanish investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 12 October 2026. https://priyalifescience.com/clinical-trials-spain/city/c-rdoba

Query this register directly

GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Spain and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,875 studies in total at the last sync on 11 Oct 2026, 03:18 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 444 of those studies with a site in Córdoba.

How many clinical trials are recruiting in Córdoba?

206 of the 444 studies on this page are recruiting new participants as of the 11 Oct 2026, 03:18 UTC sync. A further 14 have not yet opened recruitment, 217 are active but closed to new participants, and 7 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Córdoba), 444 studies
Phase	Studies	Recruiting	Share
Phase 3	234	97	52.7%
Phase 2	75	29	16.9%
Observational	51	33	11.5%
Not applicable	32	21	7.2%
Phase 1	16	7	3.6%
Phase 1/2	16	9	3.6%
Phase 2/3	14	6	3.2%
Phase 4	6	4	1.4%

Most active sponsors

Lead sponsors with the most studies (Córdoba)
Lead sponsor	Studies	Recruiting
AstraZeneca	40	15
Novartis Pharmaceuticals	22	9
AbbVie	16	5
Maimónides Biomedical Research Institute of Córdoba	16	8
Janssen Research & Development, LLC	15	5
Hoffmann-La Roche	14	4
Merck Sharp & Dohme LLC	12	8
Eli Lilly and Company	11	6
GlaxoSmithKline	9	4
Pfizer	9	6

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.