Ireland
--:--IST
Priya Life Science Compound trial record
Compound · clinical trials

Fluzoparib clinical trials

Also listed in trial records as Fuzuloparib , Abiraterone acetate and Prednisone, SHR3162, SHR-3162
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 20 trials in our China, UK, USA, France, Spain, Belgium, Poland, Czechia, South Korea, Taiwan and Australia registers that name Fluzoparib as an intervention. Synced 9 Nov 2026
20Current trials
15Recruiting now
14Lead sponsors
11Country registers
At a glance

Fluzoparib is named as an intervention in 20 current clinical trials in our China, UK, USA, France, Spain, Belgium, Poland, Czechia, South Korea, Taiwan and Australia registers. 15 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Fudan University (5). The most-studied condition is Ovarian Cancer.

How Fluzoparib works

All drug targets →
Diseases it has been tested for in clinical trials, by furthest phase
  • Breast cancerPhase 3
  • Fallopian tube cancerPhase 3
  • Malignant pancreatic neoplasmPhase 3
  • Ovarian cancerPhase 3
  • Ovarian carcinomaPhase 3
  • Pancreatic neoplasmPhase 3
  • Primary peritoneal carcinomaPhase 3
  • Prostate cancerPhase 3
  • Triple-negative breast carcinomaPhase 3
  • Ewing sarcomaPhase 2
28 diseases in all

Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL3930624, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 13763, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.

Patient leaflets for Fluzoparib

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

  • UK
    United Kingdom: Search MHRA Products
    Patient information leaflets and SmPCs for UK-licensed products.
  • US
    United States: Search DailyMed
    FDA-approved labels, including patient and medication guides.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Trials by status

  • Recruiting1575%
  • Not yet open315%
  • Active, closed210%

Trials by phase

  • Phase 21365%
  • Phase 3525%
  • Phase 1/215%
  • Observational15%
01

Clinical trials of Fluzoparib

20 trials
StudyPhaseStatusLead sponsorRegisters
Efficacy and Safety of Fluzoparib Combined With Adjuvant Endocrine Therapy for HR+/HER2- SNF3-subtype Early Breast Cancer (BCTOP-L-A01)
NCT05891093 · ClinicalTrials.gov ↗ · Breast Cancer
Phase 3 Recruiting Fudan University China
Randomized, Open, Controlled, Multicenter Phase III Clinical Study of Fluzoparib in Combination With Apatinib Versus Investigator-Selected Chemotherapy for HRD-Positive/HER2-negative Advanced Breast Cancer
NCT06255392 · ClinicalTrials.gov ↗ · Fludzoparib" and Anti-angiogenic, HRD-positive/HER2-negative Advanced Breast Cancer
Phase 3 Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University China
Fluzoparib+Bevacizumab/Dietary Intervention vs Fluzoparib Monotherapy as First-line Maintenance in HRD+/- Advanced Ovarian Cancer
NCT06954584 · Ovarian Cancer
Phase 3 Recruiting Tongji Hospital China
Fluzoparib Combined With Camrelizumab for Neoadjuvant Treatment of Embryogenic BRCA Mutation HER2 Negative Breast Cancer: an Open, Single Arm, Multicenter Study
NCT05576389 · ClinicalTrials.gov ↗ · Germline BRCA-mutated HER2-negative Breast Cancer
Phase 2 Recruiting Peking University People's Hospital China
Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy
NCT05582499 · ClinicalTrials.gov ↗ · Breast Neoplasm, Breast Cancer, Breast Tumors
Phase 2 Recruiting Fudan University China
SNF Platform Study of HR+/ HER2-advanced Breast Cancer
NCT05594095 · ClinicalTrials.gov ↗ · Breast Neoplasm, Breast Cancer, Hormone Receptor Positive Tumor
Phase 2 Recruiting Fudan University China
PARP Inhibitor With CDK4/6 Inhibitor and Endocrine Therapy in HR+/ HER2-Advanced Breast Cancer
NCT05759546 · ClinicalTrials.gov ↗ · Breast Cancer Metastatic
Phase 2 Recruiting Fudan University China
Neoadjuvant Camrelizumab and Fluzoparib and Nab-paclitaxel in Early Breast Cancer With HRR Gene Mutation
NCT05761470 · ClinicalTrials.gov ↗ · Her-2 Negative Breast Cancer, HRR Gene Mutation
Phase 2 Recruiting Ying Lin China
Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma
NCT05894018 · ClinicalTrials.gov ↗ · Sarcoma,Soft Tissue, Brachytherapy, Poly(ADP-ribose) Polymerase Inhibitors
Phase 2 Recruiting Fujun Zhang China
Camrelizumab Plus Fluzoparib for TP-53 Mutated Endometrial Cancer
NCT06413992 · ClinicalTrials.gov ↗ · Endometrial Carcinoma, TP53 Mutation, Recurrent or Metastatic
Phase 2 Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences China
Fluzoparib With or Without Bevacizumab for Neoadjuvant Therapy in Advanced Ovarian Cancer
NCT06735326 · ClinicalTrials.gov ↗ · Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
Phase 2 Recruiting Qilu Hospital of Shandong University China
Phase II Study of Irinotecan Liposome (II) Combined With Temozolomide and Fluzoparib in Recurrent or Metastatic Ewing Sarcoma
NCT06827717 · ClinicalTrials.gov ↗ · Ewing Sarcoma
Phase 2 Recruiting Sun Yat-sen University China
A Single-Arm Phase Ⅱ Study of Fluzoparib Maintenance in Platinum-sensitive Advanced Triple-Negative Breast Cance
NCT07321015 · ClinicalTrials.gov ↗ · Platinum-sensitive, TNBC, Triple Negative Breast Cancer, BRCA1/2 Mutation or Not
Phase 2 Recruiting Tianjin Medical University Cancer Institute and Hospital China
A Clinical Study of JS105 in Combination With Other Anti-tumor Therapies in Patients With Solid Tumors
NCT06208410 · ClinicalTrials.gov ↗ · Advanced Solid Tumors
Phase 1/2 Recruiting Risen (Suzhou) Pharma Tech Co., Ltd China
A Non-interventional Registry Study of Fluzoparib in the Treatment of Ovarian Cancer
NCT05206890 · ClinicalTrials.gov ↗ · Ovarian Cancer
Observational Recruiting Tongji Hospital China
First-line Maintenance Treatment With Fluzoparib Plus Bevacizumab in Advanced BRCA Wild Type Ovarian Cancer
NCT06063070 · ClinicalTrials.gov ↗ · Ovarian Cancer, High Grade Serous Adenocarcinoma of Ovary, High Grade Endometrioid Ovarian Cancer
Phase 2 Not yet open Sun Yat-sen University China
Fluzoparib Combined With Dalpiciclib for Platinum Resistant Recurrent Ovarian Cancer
NCT06552858 · ClinicalTrials.gov ↗ · Ovarian Cancer
Phase 2 Not yet open Fudan University China
Retlirafusp Alfa Combined With Chemotherapy or Fuzuloparib for Triple-Negative Breast Cancer
NCT07752550 · ClinicalTrials.gov ↗ · Triple-Negative Breast Cancer (TNBC)
Phase 2 Not yet open Harbin Medical University China
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study of Fuzuloparib Combined With Abiraterone Acetate and Prednisone (AA-P) Versus Placebo Combined With AA-P as First-Line Treatment in Patients With Metastatic Castration-Resistant Prostate Cancer
NCT04691804 · Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Phase 3 Active, closed Jiangsu HengRui Medicine Co., Ltd UK, USA, China, France, Spain, Belgium, Poland, Czechia, South Korea, Taiwan, Australia
PARP Inhibitor With CDK4/ 6 Inhibitor and Endocrine Therapy in HR+/ HER2-Advanced Breast Cancer
NCT06612814 · ClinicalTrials.gov ↗ · Breast Cancer Metastatic
Phase 3 Active, closed Zhimin Shao China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Fluzoparib

30 conditions
All 30 conditions
Condition (as registered)Trials
Ovarian Cancer5
Breast Cancer3
Breast Neoplasm2
Triple-Negative Breast Cancer (TNBC)2
Breast Cancer Metastatic2
Metastatic Castration-Resistant Prostate Cancer (mCRPC)1
Hormone Receptor Positive Tumor1
HER2-negative Breast Cancer1
Sarcoma,Soft Tissue1
Brachytherapy1
Poly(ADP-ribose) Polymerase Inhibitors1
Advanced Solid Tumors1
Platinum-sensitive1
TNBC, Triple Negative Breast Cancer1
BRCA1/2 Mutation or Not1
Breast Tumors1
High Grade Serous Adenocarcinoma of Ovary1
High Grade Endometrioid Ovarian Cancer1
Primary Peritoneal Cancer1
Fallopian Tube Cancer1
Peritoneal Cancer1
Germline BRCA-mutated HER2-negative Breast Cancer1
Fludzoparib" and Anti-angiogenic1
HRD-positive/HER2-negative Advanced Breast Cancer1
Ewing Sarcoma1
Endometrial Carcinoma1
TP53 Mutation1
Recurrent or Metastatic1
Her-2 Negative Breast Cancer1
HRR Gene Mutation1
05

Related compounds

06

Questions about Fluzoparib trials

How many clinical trials are testing Fluzoparib?

20 current trials in our China, UK, USA, France, Spain, Belgium, Poland, Czechia, South Korea, Taiwan and Australia registers name Fluzoparib (also registered as SHR3162) as a drug or biological intervention, as of the registry sync on 9 November 2026. Completed and withdrawn studies are not counted.

Are Fluzoparib trials recruiting patients?

Yes. 15 of the 20 trials are recruiting: 15 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Fluzoparib clinical trials?

Fudan University (5), Tongji Hospital (2), Sun Yat-sen University (2) and Jiangsu HengRui Medicine Co., Ltd (1), among 14 lead sponsors in total. The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Fluzoparib works or whether it is effective, and it is not medical advice.

Approvals, shortages and trials, every Friday

One email a week with new EMA and FDA approvals, EU and US medicine shortages, how many trials are recruiting in Ireland, and the week's Irish pharma news.

Free. Unsubscribe from any email with one click. See our privacy policy.

How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Fluzoparib works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Fluzoparib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.