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Clinical Trials in Spain / NCT06353594
Recruiting Not applicable

Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With STEMI

NCT06353594 · tracked via the Priya Life Science Spain tracker
Sponsor
Hospital Universitario La Fe
Phase
Not applicable
Started
2024-03-11
Last updated
2026-05-28

Condition(s) studied

ST Elevation Myocardial Infarction

Investigational drug(s) / intervention(s)

Primary PCI

Primary PCI: Coronary percutaneous revascularization

Study summary

The objective is to compare a reduced stent strategy based on drug-coated balloon (DCB) percutaneous coronary intervention (PCI) with conventional drug-eluting stent (DES) coronary revascularization in patients presenting with ST-segment myocardial infarction (STEMI).

Randomization will be performed after successful culprit-lesion guidewire crossing and flow restoration. Random allocation in a 1:1 fashion to one of the following strategies:

* Study group: reduced stent PCI strategy (DCB-based)
* Control group: conventional PCI strategy (DES-based).

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: \- Patients presenting with STEMI and indication to undergo pPCI. Exclusion Criteria: * Life expectancy \<1 year due 1 to non-cardiac disease. * Inability to provide informed consent. * Cardiogenic shock. * Left ventricular ejection fraction \<15%. * Left main disease. * Stent thrombosis * Patients with prior bypass graft lesions requiring PCI (culprit or non culprit lesions). * Patients with chronic total occlusions. * Untreatable coronary disease. * Non-identified culprit lesion. * Known allergy to aspirin, ticagrelor, prasugrel, clopidogrel, paclitaxel or sirolimus.

Primary outcome measure(s)

Trial sites (23)

FacilityCityRegionStatus
Hospital Universitario Juan Ramón Jiménez Huelva Huelva Recruiting
Hospital Universitario Y Politecnico La Fe Valencia Valencia Recruiting
Complejo Hospitalario Universitario de A Coruña A Coruña Spain Recruiting
Hospital Universitario de Burgos Burgos Spain Recruiting
Consorcio Hospitalario Provincial de Castellon Castelló Spain Recruiting
Hospital Universitario Reina Sofía de Córdoba Córdoba Spain Recruiting
Hospital General Universitario de Elche Elche Spain Recruiting
Hospital Universitario Clínico San Cecilio Granada Spain Recruiting
Hospital Universitari de Bellvitge L'Hospitalet de Llobregat Spain Recruiting
Hospital Universitario de La Princesa Madrid Spain Recruiting
Hospital Universitario La Paz Madrid Spain Recruiting
Hospital Universitario Puerta de Hierro Majadahonda Madrid Spain Recruiting
Hospital Universitario Regional de Malaga Málaga Spain Recruiting
Hospital de Mérida Mérida Spain Recruiting
Hospital Universitario de Navarra Pamplona Spain Recruiting
Complejo Hospitalario Universitario de Santiago de Compostela Santiago de Compostela Spain Recruiting
Hospital Universitario Virgen Del Rocio Seville Spain Recruiting
Hospital Universitari Joan Xxiii de Tarragona Tarragona Spain Recruiting
Hospital Universitario Mutua de Terrassa Terrassa Spain Recruiting
Consorcio Hospital General Universitario de Valencia Valencia Spain Recruiting
Hospital Clinico Universitario de Valladolid Valladolid Spain Recruiting
Hospital Clinico Universitario Lozano Blesa Zaragoza Spain Recruiting
Hospital Universitario Miguel Servet Zaragoza Spain Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06353594 on ClinicalTrials.gov ↗ ← All trials in Spain