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Clinical Trials in Spain / NCT07466407
Starting soon Not applicable

Effects of HMB and Rehabilitation Program in Athletes With Patellar Tendinopathy

NCT07466407 · tracked via the Priya Life Science Spain tracker
Phase
Not applicable
Started
2026-03-01
Last updated
2026-03-12

Condition(s) studied

Patellar Tendinopathy

Investigational drug(s) / intervention(s)

Eccentric exercise and extracorporeal shock wave therapyBeta-hydroxy-beta-methylbutyrate (HMB)

Eccentric exercise and extracorporeal shock wave therapy: Participants undergo a standardized rehabilitation program consisting of eccentric exercise and extracorporeal shock wave therapy.

Beta-hydroxy-beta-methylbutyrate (HMB): Participants ingest 3 g/day of beta-hydroxy-beta-methylbutyrate (HMB) in capsule form, administered 60 minutes before each eccentric training session during the 8-week intervention period.

Study summary

This randomized, double-blind, placebo-controlled clinical trial evaluates the effects of oral beta-hydroxy-beta-methylbutyrate (HMB) supplementation combined with an eccentric exercise and extracorporeal shockwave rehabilitation program on pain, tendon morphology, and neuromuscular performance in athletes with patellar tendinopathy.

Thirty athletes with a confirmed diagnosis of patellar tendinopathy are randomized to receive either HMB supplementation (3 g/day) or placebo during an 8-week rehabilitation program. Participants are evaluated at baseline, week 4, and week 8.

The primary outcome is pain and functional limitation assessed using the Victorian Institute of Sport Assessment-Patella (VISA-P) questionnaire. Secondary outcomes include patellar tendon thickness measured by ultrasound imaging, countermovement jump (CMJ) performance, and neuromuscular performance variables derived from an incremental squat test using a linear position transducer.

The aim of the study is to determine whether HMB supplementation enhances clinical recovery and neuromuscular performance when combined with a standardized rehabilitation program compared with placebo.

Eligibility

Sex
ALL
Min age
18 Years
Max age
49 Years
Healthy volunteers
No
Inclusion Criteria: * Age between 18 and 49 years * Clinical diagnosis of patellar tendinopathy confirmed by a physician and physiotherapist * Competitive athlete in sports involving repetitive knee loading (e.g., basketball, volleyball, handball, athletics) * Minimum training frequency of three sessions per week * No knee surgery within the previous 12 months * No nutritional supplementation within the previous 3 months * No injection therapy (analgesics or platelet-rich plasma) within the previous 12 months * Non-smoker * Signed informed consent Exclusion Criteria: * Any musculoskeletal injury other than patellar tendinopathy affecting performance * Systemic disease affecting musculoskeletal function * Inability to comply with the rehabilitation or supplementation protocol

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Clínica Fisio-Agil Córdoba Córdoba

More Universidad Complutense de Madrid trials in Spain

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07466407 on ClinicalTrials.gov ↗ ← All trials in Spain