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Trackers› Clinical trials› Milan
Clinical trial register · Italy

Clinical Trials in Milan, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Italy and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 6791 matching records held by the registry are in this view. Synced 11 Oct 2026, 03:19 UTC
6791
Studies in scope
all four open statuses
4079
Recruiting now
open to new participants
1019
Lead sponsors
across recruiting studies
Top sites
Milan 2846 Bologna 1303 Roma 1272 Naples 983 Rome 968
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
IRCCS San Raffaele160 AstraZeneca137 Merck Sharp & Dohme LLC98 Hoffmann-La Roche80 Novartis Pharmaceuticals73
Site location
Milan2846 Bologna1303 Roma1272 Naples983 Rome968
All 489 locations
Target enrolment
to

Trials with a site in Milan

2846 of 6791 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Italy
Start
Active, closed
Evolut™ EXPAND TAVR II Pivotal Trial
NCT05149755Moderate Aortic Valve Stenosis
Medtronic Cardiovascular
Not applicable
650
Catania, Milan, San Donato Milanese
2022-04-27
Recruiting
EspeRare Foundation
Phase 2
20
Milan
2022-04-26
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
50
Bologna, Bari, Milan
2022-04-23
Recruiting
UNICANCER
Phase 3
300
Bari, Candiolo, Foggia, Meldola, Milan, Naples, Roma, Rozzano
2022-04-19
By invitation
AstraZeneca
Phase 3
214
Arezzo, Bari, Catania, Meldola, Milan, Modena, Padova, Pisa
2022-04-19
Active, closed
Sanofi
Phase 3
43
Milan, Naples
2022-04-18
Active, closed
ARCAGY/ GINECO GROUP
Phase 3
260
Aviano, Bari, Biella, Brescia, Faenza, Lucca, Lugo, Milan
2022-04-15
Recruiting
AstraZeneca
Phase 2
630
Aviano, Brescia, Catanzaro, Florence, Genova, Meldola, Milan, Monza
2022-04-14
Recruiting
Cogent Biosciences, Inc.
Phase 3
482
Aviano, Bologna, Brescia, Candiolo, Florence, Meldola, Milan, Palermo
2022-04-14
Active, closed
Eli Lilly and Company
Phase 3
925
Meldola, Rome, Milan, Castelfranco Veneto, Terni, Trento
2022-04-14
Recruiting
A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies
NCT05131022Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), Diffuse Large B Cell Lymphoma (DLBCL), Follicular Lymphoma (FL)
DrugBexobrutideg
Nurix Therapeutics, Inc.
Phase 1
572
Bologna, Brescia, Milan, Rome
2022-04-13
Recruiting
The DRAGON 2 Trial
NCT05428735Colorectal Cancer Liver Metastases (CRLM), Small Future Liver Remnant (FLR)
Maastricht University
Not applicable
348
Milan
2022-04-01
Recruiting
Euresist Network GEIE
Observational
1,800
Milan
2022-04-01
Active, closed
Precise Procedural and PCI Plan (P4)
NCT05253677Coronary Artery Disease
CoreAalst BV
Not applicable
1,090
Cona, Milan
2022-04-01
Active, closed
Protagonist Therapeutics, Inc.
Phase 3
293
Meldola, Bergamo, Bologna, Brescia, Florence, Milan, Pavia, Pesaro
2022-04-01
Active, closed
Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Phase 2
154
Turin, Florence, Genova, Milan, Pavia, Reggio Emilia, Roma
2022-03-29
Recruiting
Iconographic Registry of Pancreatobiliary Endoscopy Procedures
NCT06344507Pancreas Neoplasm, Cancer of Pancreas, Pancreatitis, Neuroendocrine Tumors
IRCCS San Raffaele
Observational
12,000
Milan
2022-03-28
Active, closed
Bayer
Phase 3
219
Bologna, Florence, Genova, Milan, Roma, Torino
2022-03-28
Active, closed
AstraZeneca
Phase 3
760
Arezzo, Florence, Milan, Roma, Rozzano, Tricase
2022-03-28
Recruiting
AbbVie
Phase 3
768
Misterbianco, Milan, Naples, Rome, Bari, Cremona, Messina, Perugia
2022-03-25
Active, closed
MaaT013 As Salvage Therapy in Ruxolitinib Refractory GI-aGVHD Patients
NCT04769895Acute Graft Versus Host Disease in Intestine, Steroid Refractory GVHD
MaaT Pharma
Phase 3
66
Ancona, Bologna, Genova, Milan, Reggio Calabria, Roma, Torino, Udine
2022-03-25
Active, closed
Pfizer
Phase 3
854
Meldola, Rome, Milan, Catania, Siena, Ancona, Bologna, Roma
2022-03-25
Recruiting
i-NEED: NEw migrainE Drugs Database
NCT07103694Episodic Migraine, Chronic Migraine, Medication Overuse Headache
IRCCS San Raffaele Roma
Observational
2,641
Milan, Rome
2022-03-24
Active, closed
Merck Sharp & Dohme LLC
Phase 3
460
Naples, Milan, Rozzano, Rome
2022-03-24
Active, closed
W.L.Gore & Associates
Observational
259
Genova, Milan, Roma
2022-03-23
Active, closed
Fondazione Italiana Linfomi - ETS
Phase 2
49
Brescia, Alessandria, Cuneo, Florence, Genova, Milan, Naples, Novara
2022-03-21
Recruiting
Amgen
Phase 3
60
Chieti, Genova, Milan, Roma
2022-03-17
Active, closed
COMBINE-INTERVENE: COMBINEd Ischemia and Vulnerable Plaque Percutaneous INTERVENtion to Reduce Cardiovascular Events
NCT05333068Multivessel Coronary Artery Disease, Ischemia, Vulnerable Plaque, Coronary Artery Disease
Diagram B.V.
Not applicable
1,223
Milan, Rome
2022-03-16
Recruiting
European Institute of Oncology
Observational
3
Milan
2022-03-15
Active, closed
Merck Sharp & Dohme LLC
Phase 3
1,800
Bari, Meldola, Rome, Milan, Orbassano, Florence, Arezzo, Bologna
2022-03-15
Active, closed
Otsuka Pharmaceutical Development & Commercialization, Inc.
Phase 3
530
Bologna, Brescia, Florence, Genova, Messina, Milan, Naples, Pavia
2022-03-15
Active, closed
Eli Lilly and Company
Phase 3
368
Misterbianco, Meldola, Udine, Bari, Grosseto, Milan, Viterbo
2022-03-11
Active, closed
BeOne Medicines
Phase 3
799
Aviano, Bologna, Florence, Milan, Novara, Padova, Pavia, Reggio Emilia
2022-03-10
Recruiting
Quantifying Systemic Immunosuppression to Personalize Cancer Therapy
NCT05621837Melanoma, Breast Cancer, Renal Cell Carcinoma, Urinary Bladder Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Observational
1,000
Milan
2022-03-10
Recruiting
Hoffmann-La Roche
Phase 1
332
Brescia, Milan, Sant'Andrea Delle Fratte (PG)
2022-03-07
Recruiting
Radiology Registry on Pancreatic Malignancies
NCT05714111Pancreatic Cancer, Pancreas Neoplasm, Pancreas Disease, Pancreas Cyst
IRCCS San Raffaele
Observational
1,300
Milan
2022-03-04
Active, closed
Daiichi Sankyo
Phase 3
740
Bari, Chieti, Lucca, Milan, Naples, Perugia, Rome, Varese
2022-03-04
Recruiting
Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance
NCT07131631Heart Failure and Reduced Ejection Fraction, Functional Mitral Regurgitation
Minneapolis Heart Institute Foundation
Observational
125
Milan
2022-03-03
Recruiting
Effectiveness and Impact on the Quality of Life of Ketogenic Diet in Pediatric Patients
NCT06309251Drug Resistant Epilepsy, Autism Spectrum Disorder, Chronic Migraine, Brain Tumor, Pediatric
Danone Nutricia SpA Società Benefit
Observational
100
Milan, Pavia, Roma
2022-03-01
Recruiting
Pfizer
Phase 3
640
Bari, Brescia, Latina, Rome, Milan
2022-02-28
Recruiting
Euresist Network GEIE
Observational
22,000
Milan, Rome
2022-02-23
Active, closed
AstraZeneca
Phase 3
390
Bari, Catania, Florence, Genova, Milan, Naples, Padova, Parma
2022-02-21
Active, closed
Istituto Auxologico Italiano
Not applicable
100
Milan
2022-02-20
Recruiting
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Phase 2
310
Naples, Modena, Aviano, Rome, Milan, Verona, Bologna
2022-02-17
Recruiting
Sanofi
Phase 3
284
Cona, Florence, Milan, Rozzano, Naples, Rome, Ancona
2022-02-15
Active, closed
177Lu-PSMA-I&T for Metastatic Castration-Resistant Prostate Cancer
NCT05204927Metastasis From Malignant Tumor of Prostate
DrugEnzalutamide
Curium US LLC
Phase 3
439
Bologna, Milan
2022-02-14
Recruiting
IRCCS San Raffaele
Observational
2,500
Milan
2022-02-14
Recruiting
Meyer Children's Hospital IRCCS
Observational
290
Florence, Bari, Brescia, Catanzaro, Lecce, Milan, Padova, Pavia
2022-02-10
Active, closed
NewAmsterdam Pharma
Phase 3
9,541
Ferrara, Milan, Naples, Palermo, Pavia, Rozzano, Terni
2022-02-07
Active, closed
Merck Sharp & Dohme LLC
Phase 3
280
Naples, Bologna, Meldola, Milan, Turin, Rome, Florence, Vicenza
2022-02-03
By invitation
UCB Biopharma SRL
Phase 3
300
Genova, Milan, Pavia, Roma
2022-02-03
Recruiting
ARCAGY/ GINECO GROUP
Phase 2
390
Florence, Milan, Monza, Sondrio
2022-02-01
Active, closed
Denali Therapeutics Inc.
Phase 1/2
85
Brescia, Florence, Milan, Tricase
2022-02-01
Not yet open
Registry and Monitoring of ImmuNe-mediated Inflammatory Diseases
NCT05172284ImmuNe-Mediated Inflammatory Diseases
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
2,000
Milan
2022-02
Active, closed
Gruppo Oncologico del Nord-Ovest
Phase 1/2
48
Milan, Pisa
2022-01-25
Active, closed
Biogen
Phase 3
45
Milan, Roma, Torino
2022-01-21
Active, closed
AstraZeneca
Phase 1/2
36
Milan, Rome
2022-01-21
Active, closed
ADH1 and ADH2 Disease Monitoring Study (DMS)
NCT05227287Autosomal Dominant Hypocalcemia
Calcilytix Therapeutics, Inc., a BridgeBio company
Observational
95
Milan, Rome
2022-01-20
Active, closed
Janssen Research & Development, LLC
Phase 3
350
Bologna, Milan, Roma
2022-01-19
Active, closed
OTL-200 in Patients With Late Juvenile Metachromatic Leukodystrophy (MLD)
NCT04283227Lysosomal Storage Diseases, Metachromatic Leukodystrophy
Orchard Therapeutics
Phase 3
6
Milan
2022-01-17
Active, closed
A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)
NCT05002127Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Gastric Adenocarcinoma
DrugsEvorpacept·Ramucirumab·Herceptin·Taxol
ALX Oncology Inc.
Phase 2/3
127
Catania, Florence, Milan, Roma, Udine
2022-01-15
Recruiting
European Institute of Oncology
Phase 2
46
Milan
2022-01-14
Active, closed
Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD
NCT05407636AMD, nAMD, Wet Age-related Macular Degeneration, wAMD
DrugsEylea·Aflibercept
AbbVie
Phase 3
735
Cona, Milan, Naples, Rome, Negrar, Bari, Chieti, Udine
2022-01-13
Recruiting
Fondazione Don Carlo Gnocchi ETS
Observational
600
Florence, Milan, Parma, Rovato
2022-01-12
Active, closed
Ascendis Pharma Oncology Division A/S
Phase 1/2
320
Cuneo, Florence, Grosseto, Lido di Camaiore, Livorno, Meldola, Milan, Modena
2022-01-11
Recruiting
Prevention of Smoking Related Diseases
NCT06451029Lung Cancer, Lung Cancer Screening, Smoking Cessation
Scientific Institute San Raffaele
Observational
189
Milan
2022-01-11
Active, closed
Noema Pharma AG
Phase 2/3
166
Rome, Florence, Milan
2022-01-11
Recruiting
Azienda Ospedaliero-Universitaria Careggi
Observational
10,000
Bari, Bologna, Florence, Foggia, Genova, Messina, Milan, Naples
2022-01-10
Active, closed
Ionis Pharmaceuticals, Inc.
Phase 3
151
Milan, Pavia
2022-01-04
Recruiting
Nuvalent Inc.
Phase 1/2
359
Ancona, Bari, Milan, Padova, Ravenna, Rome
2022-01-04
Recruiting
European Institute of Oncology
Not applicable
318
Milan
2022-01-01
Active, closed
Società Italiana Talassemie ed Emoglobinopatie
Observational
1,000
Torino, Cagliari, Ferrara, Genova, Milan, Naples, Palermo, Roma
2022-01-01
Recruiting
Niguarda Hospital
Observational
100
Milan
2022-01-01
Recruiting
Niguarda Hospital
Observational
360
Milan
2022-01-01
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
68
Milan
2021-12-21
Active, closed
ITM Solucin GmbH
Phase 3
259
Messina, Milan, Rome
2021-12-21
Active, closed
A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT)
NCT04770753Non-Transfusion-dependent Alpha-Thalassemia, Non-Transfusion-dependent Beta-Thalassemia
DrugMitapivat
Agios Pharmaceuticals, Inc.
Phase 3
194
Brindisi, Cagliari, Ferrara, Genova, Milan, Modena, Naples, Orbassano
2021-12-20
Recruiting
Interceptive Maxillary Expansion to Relief Anterior Crowding in the Mixed Dentition
NCT06187337Crowding of Anterior Maxillary Teeth, Orthodontics, Interceptive, Orthodontics, Corrective, Palatal Expansion Technique
Region Örebro County
Not applicable
60
Coppito, Milan
2021-12-20
Active, closed
Eli Lilly and Company
Phase 3
152
Bari, Milan, Rozzano, Naples, Orbassano, Padova
2021-12-20
Active, closed
Novartis Pharmaceuticals
Phase 3
210
Bari, Bergamo, Bologna, Florence, Genova, Milan, Rozzano, Palermo
2021-12-17
Active, closed
Novartis Pharmaceuticals
Phase 3
1,000
Milan, Roma, Verona, Novara
2021-12-16
Recruiting
Takeda
Phase 2
135
Bari, Bologna, Brescia, Florence, Genova, Milan, Reggio Emilia, Roma
2021-12-16
By invitation
Long-Term Follow-Up Study After Gene-Modified Cell Treatment in Kite Studies
NCT05041309Solid and Hematological Malignancies, Autoimmune Diseases
DrugsKITE-197·SPRX002·KITE-753·Tecartus
Kite, A Gilead Company
Observational
1,500
Milan, Rome
2021-12-15
Recruiting
Neurocognitive Assessment Platform 4 Alzheimer
NCT07272811MCI, MCI Conversion to Dementia, AMCI - Amnestic Mild Cognitive Impairment, Alzheimer Disease
IRCCS San Raffaele
Observational
100
Milan
2021-12-15
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
68
Milan
2021-12-14
Recruiting
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
NCT05176483Renal Cell Carcinoma (RCC), Metastatic Castration-Resistant Prostate Cancer (mCRPC), Urothelial Carcinoma (UC), Solid Tumor
DrugsZanzalintinib·Relatlimab·Yervoy·Ipilimumab
Exelixis
Phase 1
1,394
Ancona, Bologna, Florence, Milan, Naples, Ravenna
2021-12-14
Active, closed
Regeneron Pharmaceuticals
Phase 3
288
Rome, Milan, Pisa, Bergamo, Roma
2021-12-14
Active, closed
GlaxoSmithKline
Phase 2
360
Bergamo, Milan, Modena, Naples, Palermo, Pisa
2021-12-14
Recruiting
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Phase 3
68
Milan
2021-12-13
Recruiting
Paolo Ghia
Phase 2
53
Milan
2021-12-13
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
52
Milan
2021-12-13
Active, closed
Merck Sharp & Dohme LLC
Phase 3
643
Bologna, Milan, Monza, Turin, Brescia
2021-12-13
Active, closed
Alnylam Pharmaceuticals
Observational
207
Orbassano, Milan, Verona
2021-12-13
Active, closed
NATURE (EnVast as an Adjunct PPCI in Subjects Presenting With STEMI)
NCT04969471Segment Elevation Myocardial Infarction (STEMI)
Vesalio
Not applicable
148
Ferrara, Milan, Roma
2021-12-09
Recruiting
Relay Therapeutics, Inc.
Phase 1
930
Milan
2021-12-08
Recruiting
UCB Biopharma SRL
Phase 3
350
Catanzaro, Genova, Milan, Pavia, Roma
2021-12-07
Active, closed
Sanofi
Phase 2
22
Avellino, Meldola, Milan
2021-12-07
By invitation
QED Therapeutics, a BridgeBio company
Phase 2
300
Milan, Roma
2021-12-06
Active, closed
Jazz Pharmaceuticals
Phase 3
920
Bologna, Candiolo, Genova, Meldola, Milan, Modena, Reggio Emilia, Rome
2021-12-02
Recruiting
H. Lundbeck A/S
Phase 3
600
Rome, Genoa, Milan, Cagliari, Florence, Pisa, Pavia
2021-12-01
Recruiting
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Phase 2
21
Milan
2021-12-01
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
65
Bologna, Milan
2021-12-01
Recruiting
Impact of Single- Versus Double-layer Hysterotomy Closure on Cesarean Niche Development: a Randomized Controlled Trial
NCT06308172Cesarean Section; Dehiscence, Uterine Bleeding, Uterus; Scar, Uterus Abnormal
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
150
Milan
2021-12-01
Active, closed
Nerviano Medical Sciences
Phase 1/2
150
Bologna, Milan, Padova, Rozzano
2021-12-01
Active, closed
Agios Pharmaceuticals, Inc.
Phase 3
258
Brindisi, Cagliari, Ferrara, Genova, Milan, Modena, Naples, Orbassano
2021-11-30
Recruiting
Blueprint Medicines Corporation
Phase 2/3
534
Milan, Florence, Bologna, Catania, Pavia, Salerno, Verona, Vicenza
2021-11-30
Active, closed
Novartis Pharmaceuticals
Phase 3
17,004
Bologna, Brescia, Cona, Florence, Grosseto, Pozzilli, Milan, Rozzano
2021-11-23
Active, closed
Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers
NCT05205330Refractory Metastatic Colorectal Cancer, Solid Tumor, Metastatic Microsatellite-stable Colorectal Cancer, Mismatch Repair Protein Proficient
DrugsVorbipiprant·Balstilimab
Rottapharm Biotech
Phase 1/2
107
Milan, Padova, Pisa
2021-11-23
Recruiting
HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial
NCT04743765Hip Fractures, Myocardial Injury
Population Health Research Institute
Not applicable
1,100
Perugia, Genova, Milan
2021-11-22
Active, closed
AstraZeneca
Phase 3
145
Milan, Naples, Roma
2021-11-19
Active, closed
Hoffmann-La Roche
Phase 3
660
Ravenna, Genoa, Milan, Torrette Di Ancona
2021-11-18
Recruiting
Azienda USL Reggio Emilia - IRCCS
Not applicable
282
Bologna, Genova, Milan, Modena, Reggio Emilia
2021-11-18
Active, closed
Gilead Sciences
Phase 3
603
Bergamo, Brescia, Catania, Catanzaro, Cremona, Milan, Pavia, Roma
2021-11-17
Recruiting
Pfizer
Phase 3
245
Genoa, Rozzano, Roma, Milan
2021-11-17
Active, closed
AbbVie
Observational
873
Bari, Catania, Genoa, Messina, Milan, Turin, Roma, Cava de' Tirreni
2021-11-17
Active, closed
Janssen Research & Development, LLC
Phase 3
776
Aviano, Meldola, Milan, Parma, Ravenna, Roma, Verona
2021-11-17
Active, closed
Prof. Massimo Filippi
Observational
40
Milan
2021-11-17
Active, closed
argenx
Phase 3
173
Ferrara, Milan, Naples
2021-11-17
Active, closed
Sirolimus-coated Balloon Versus Drug-eluting Stent in Native Coronary Vessels - TRANSFORM II
NCT04893291Coronary Artery Disease, Coronary Artery Stenosis
Fondazione Ricerca e Innovazione Cardiovascolare ETS
Not applicable
1,820
Aversa, Brescia, Genova, La Spezia, Milan, Paderno Dugnano, Palermo, Roma
2021-11-16
Recruiting
Advances in Neuropsychological Diagnostics
NCT05794061Cognitive Impairment, Dementia, Psychiatric Disorder
Istituto Auxologico Italiano
Observational
300
Milan
2021-11-11
Active, closed
Sanofi
Phase 2
109
Milan, Rome
2021-11-10
By invitation
The Role of Advanced Electroencephalographic Data as Marker of Pathology and Prognosis in Primary Dementias
NCT06826157Alzheimer Disease, Lewy Body Dementia (LBD), Mild Alzheimer Disease, Frontotemporal Dementia (FTD)
IRCCS San Raffaele
Not applicable
175
Milan
2021-11-05
Active, closed
Amgen
Phase 3
303
Bari, Bergamo, Bologna, Genova, Lecce, Mestre (VE), Milan, Naples
2021-11-02
Active, closed
AstraZeneca
Phase 3
148
Arezzo, Avellino, Bari, Bologna, Florence, Meldola, Milan, Naples
2021-10-28
Active, closed
AstraZeneca
Phase 3
454
Milan, Monza, Orbassano, Parma, Roma, Verona
2021-10-28
Active, closed
Hoffmann-La Roche
Phase 3
303
Rome, Milan, Pisa, Cona (Ferrara), Padova
2021-10-26
Active, closed
AstraZeneca
Phase 3
927
Bologna, Candiolo, Livorno, Milan, Naples, Negrar, Padova, Roma
2021-10-25
Recruiting
Bayer
Phase 1/2
400
Aviano, Milan, Orbassano, Parma, Roma, Rozzano, Verona
2021-10-25
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
20
Milan
2021-10-24
Recruiting
Hoffmann-La Roche
Phase 1
542
Naples, Meldola, Rome, Milan, Padova
2021-10-22
Active, closed
Camurus AB
Phase 3
332
Bari, Bologna, Brescia, Florence, Genova, Meldola, Milan, Modena
2021-10-22
Active, closed
Novartis Pharmaceuticals
Phase 1
137
Milan, Rozzano
2021-10-21
Active, closed
International Extranodal Lymphoma Study Group (IELSG)
Phase 2
26
Brescia, Milan, Novara, Ravenna, Reggio Emilia, Varese
2021-10-20
Recruiting
San Raffaele Registry on Liver Cancer
NCT07704489Liver and Intrahepatic Biliary Tract Cancer
IRCCS San Raffaele
Observational
4,000
Milan
2021-10-20
Active, closed
AstraZeneca
Phase 3
732
Bologna, Candiolo, Florence, Meldola, Milan, Naples, Padova, Prato
2021-10-18
Recruiting
AstraZeneca
Phase 1/2
460
Milan, Modena, Roma
2021-10-18
Active, closed
A Long-term Extension Study of Ustekinumab in Pediatric Participants
NCT05092269Crohn Disease, Colitis, Ulcerative, Arthritis, Psoriatic
DrugUstekinumab
Janssen Research & Development, LLC
Phase 3
159
Milan
2021-10-18
Recruiting
Keratized Mucosa in CG Implant Placement: CTG vs Flapless
NCT05073952Variation of Keratinized Mucosa After Implant Surgery
University of Milan
Not applicable
44
Milan
2021-10-18
Active, closed
Study of Vimseltinib for Tenosynovial Giant Cell Tumor
NCT05059262Tenosynovial Giant Cell Tumor, Pigmented Villonodular Synovitis, Giant Cell Tumor of Tendon Sheath, Tenosynovial Giant Cell Tumor, Diffuse
DrugVimseltinib
Deciphera Pharmaceuticals, LLC
Phase 3
123
Bologna, Milan, Naples, Padua, Rome
2021-10-14
Recruiting
Study on the Diagnosis and Management of CLL in Italy by GIMEMA
NCT04867915Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, MBL-CLL - Monoclonal B-Cell Lymphocytosis Chronic Lymphocytic Leukaemia-Type
Gruppo Italiano Malattie EMatologiche dell'Adulto
Observational
12,500
Alessandria, Brescia, Brindisi, Candiolo, Florence, Messina, Mestre, Milan
2021-10-13
Active, closed
Hoffmann-La Roche
Phase 2
176
Bari, Naples, Rome, Milan
2021-10-07
Active, closed
A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP
NCT04971226Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive
DrugsBosutinib·Asciminib·ABL001·Nilotinib
Novartis Pharmaceuticals
Phase 3
405
Bologna, Milan, Reggio Emilia, Roma, Verona
2021-10-06
Active, closed
Tethis S.p.A.
Observational
84
Milan
2021-10-04
Recruiting
Pfizer
Phase 3
893
Meldola, Milan, Monza, Catania, Bologna, Genova, Roma
2021-10-04
Recruiting
IRCCS San Raffaele
Observational
15
Milan
2021-10-01
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
40
Ancona, Bologna, Milan
2021-09-29
Active, closed
Pfizer
Phase 3
77
Milan, Rozzano, Ancona
2021-09-29
Active, closed
Study of INBRX-109 in Conventional Chondrosarcoma
NCT04950075Conventional Chondrosarcoma
DrugINBRX-109
Inhibrx Biosciences, Inc
Phase 2
206
Bologna, Candiolo, Milan, Palermo, Prato, Roma
2021-09-23
Active, closed
Loxo Oncology, Inc.
Phase 3
282
Rionero in Vulture, Bergamo, Brescia, Meldola, Milan, Monza, Novara, Perugia
2021-09-23
Active, closed
Mirum Pharmaceuticals, Inc.
Phase 2
333
Ancona, Bergamo, Milan, Modena, Monza, Padova, Palermo, Pisa
2021-09-22
Active, closed
A Non-interventional Cohort Safety Study of Patients With hATTR-PN
NCT04850105Hereditary Transthyretin Amyloidosis With Polyneuropthy
Akcea Therapeutics
Observational
202
Roma, Bologna, Genova, Messina, Milan, Naples, Pavia
2021-09-21
Active, closed
Loxo Oncology, Inc.
Phase 3
600
Bologna, Catanzaro, Cona, Cuneo, Florence, Meldola, Milan, Modena
2021-09-20
Recruiting
BeOne Medicines
Phase 1/2
246
Ancona, Bari, Bologna, Meldola, Milan
2021-09-16
Active, closed
Merck Sharp & Dohme LLC
Phase 3
2,000
Rome, Milan, Pavia
2021-09-15
Active, closed
Hoffmann-La Roche
Phase 1/2
42
Genoa, Milan, Turin
2021-09-14
Recruiting
L.Molteni & C. dei F.lli Alitti-Soc. di Esercizio S.p.A.
Not applicable
78
Arezzo, Florence, Genova, Milan, Palermo, Perugia, Pistoia
2021-09-14
Recruiting
Italian Sarcoma Group
Phase 2
16
Prato, Roma, Candiolo, Bologna, Milan, Palermo
2021-09-14
Recruiting
A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies
NCT05006716B-cell Malignancy, Marginal Zone Lymphoma, Follicular Lymphoma, Non-Hodgkin Lymphoma
DrugTacabrutideg
BeOne Medicines
Phase 1/2
689
Bologna, Milan, Roma, Verona
2021-09-13
Active, closed
Tethis S.p.A.
Observational
60
Milan
2021-09-09
Recruiting
Amgen
Phase 3
60
Chieti, Genova, Milan, Roma
2021-09-09
Active, closed
Nuvation Bio Inc.
Phase 2
217
Bari, Catania, Milan, Monserrato, Naples, Roma
2021-09-01
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
200
Milan
2021-09-01
Recruiting
Association of Plasma N-terminal Pro-Brain Natriuretic Peptide Levels With the Burden of Coronary Artery Disease
NCT07013344Chronic Coronary Syndrome, Chronic Coronary Total Occlusion, Coronary Arterial Disease (CAD), Stable Chronic Angina
IRCCS Ospedale San Raffaele
Observational
800
Milan
2021-09-01
Active, closed
Immunome, Inc.
Phase 2/3
198
Bologna, Milan, Rome
2021-09-01
Active, closed
Hoffmann-La Roche
Phase 3
4,170
Avellino, Naples, Bologna, Meldola, Reggio Emilia, Roma, Milan, Rozzano (MI)
2021-08-27
Active, closed
Inventiva Pharma
Phase 3
1,000
San Giovanni Rotondo, Milan, Naples, Palermo, Roma, Bologna, Novara, Torino
2021-08-19
Active, closed
Merck Sharp & Dohme LLC
Phase 1/2
110
Rozzano, Siena, Milan
2021-08-19
Recruiting
Study of the R3 Vascular Drug-Eluting Bioresorbable Scaffold in Treating Below the Knee Arterial Disease
NCT04912323Peripheral Arterial Disease, Atherosclerotic Lesion, Lower Extremity Ischemia, Lower Extremity Claudication
R3 Vascular Inc.
Not applicable
30
Arezzo, Cotignola, Milan
2021-08-17
Recruiting
Merck Sharp & Dohme LLC
Phase 2
355
Naples, Milan, Siena, Bologna, Brescia, Verona
2021-08-12
Recruiting
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
NCT05003986Focal Segmental Glomerulosclerosis, Minimal Change Disease, Immunoglobulin A Nephropathy, IgA Vasculitis
DrugSparsentan
Travere Therapeutics, Inc.
Phase 2
67
Bari, Genova, Milan, Padova, Roma
2021-08-12
Active, closed
HUYABIO International, LLC.
Phase 3
450
Milan, Perugia, Bari, Bologna, Misterbianco, Naples, Palermo, Roma
2021-08-12
Active, closed
Hoffmann-La Roche
Phase 1
119
Milan
2021-08-11
Active, closed
Tanabe Pharma America, Inc.
Phase 3
286
Roma, Brescia BS, Cuneo CN, Genova GE, Milan, Modena, Trieste TS
2021-08-10
Active, closed
AstraZeneca
Phase 3
712
Bari, Florence, Meldola, Milan, Padova, Pozzuoli, Reggio Emilia, Roma
2021-08-05
Active, closed
MedSIR
Phase 2
393
Bologna, Milan, Monza, Parma, Piacenza, Roma
2021-08-05
Active, closed
Assistance Publique - Hôpitaux de Paris
Phase 3
800
Ancona, Cremona, Empoli, Florence, Milan, Perugia, Treviso
2021-08-04
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
500
Milan
2021-08-02
Recruiting
European Institute of Oncology
Not applicable
79
Milan
2021-07-31
Recruiting
Novartis Pharmaceuticals
Phase 1/2
222
Meldola, Milan, Naples, Reggio Emilia
2021-07-30
Recruiting
Novartis Pharmaceuticals
Phase 3
98
Ranica, Milan, Roma
2021-07-28
Active, closed
Novartis Pharmaceuticals
Phase 3
208
Ascoli Piceno, Avellino, Florence, Milan, Roma, Torino, Bassano del Grappa
2021-07-27
By invitation
UCB Biopharma SRL
Phase 3
760
Catania, Milan
2021-07-27
Recruiting
Bristol-Myers Squibb
Phase 3
102
Genoa, Milan, Torino
2021-07-21
Recruiting
Janssen Research & Development, LLC
Phase 3
199
Catania, Cefalù, Milan, Naples, Pavia, Roma
2021-07-15
Active, closed
Hoffmann-La Roche
Phase 3
451
Chieti, Bari, Trieste, Rome, Milan, Torrette - Ancona, Florence, Perugia
2021-07-14
Recruiting
Pancreatic Cancer Evolution Upon Treatment
NCT05195281Pancreatic Cancer
IRCCS San Raffaele
Not applicable
80
Milan
2021-07-14
Recruiting
Valved Graft PMCF Study
NCT04754217Aortic Valve Disease, Ascending Aorta Abnormality, Aortic Dissection
Abbott Medical Devices
Observational
260
Bologna, Milan, San Donato Milanese
2021-07-13
Active, closed
Evaluation of TAVR Using the NAVITOR Valve in a Global Investigation
NCT04788888Symptomatic Severe Aortic Stenosis
Abbott Medical Devices
Not applicable
434
Castel Volturno, Milan, Padova
2021-07-13
Recruiting
Meyer Children's Hospital IRCCS
Observational
103
Bergamo, Brescia, Florence, Genova, Milan, Palermo, Torino, Trieste
2021-07-13
Recruiting
Centro Cardiologico Monzino
Observational
175
Milan
2021-07-08
Recruiting
Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs
NCT04613921Liver Diseases, Liver Cirrhosis, Acute-On-Chronic Liver Failure, Liver Transplant; Complications
European Foundation for Study of Chronic Liver Failure
Observational
3,000
Bergamo, Bologna, Milan, Padova
2021-07-08
Recruiting
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Phase 3
434
Bologna, Meldola, Milan, Pisa, Verona
2021-07-06
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
60
Milan
2021-07-01
Recruiting
Health-care Quality in Semi-intensive Care Units
NCT04676347Semi-intensive Care Unit, Evaluation, Quality
Mario Negri Institute for Pharmacological Research
Observational
39,000
Milan, Alessandria, Bassano del Grappa, Bologna, Catania, Cesena, Livorno, Lodi
2021-07-01
Active, closed
AstraZeneca
Phase 3
315
Bergamo, Bologna, Florence, Meldola, Milan, Misterbianco, Naples, Padova
2021-06-30
Recruiting
H. Lundbeck A/S
Phase 3
285
Pavia, Rome, Milan, Cagliari, Genoa
2021-06-30
Recruiting
Corcym S.r.l
Observational
2,150
Ancona, Bologna, Brescia, Lecce, Massa, Milan, Naples, Palermo
2021-06-29
Active, closed
GlaxoSmithKline
Phase 3
40
Ancona, Bologna, Brindisi, Candiolo to, Catania, Genova, Meldola FC, Milan
2021-06-28
Active, closed
Merck Sharp & Dohme LLC
Phase 2
302
Milan, Naples, Padova
2021-06-25
Active, closed
Neurocrine Biosciences
Phase 3
103
Bologna, Milan, Naples, Roma
2021-06-25
Active, closed
Mirati Therapeutics Inc.
Phase 3
461
Avellino, Biella, Cagliari, Candiolo, Lido di Camaiore, Meldola, Milan, Naples
2021-06-24
Recruiting
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Observational
337
Milan
2021-06-23
Active, closed
AstraZeneca
Phase 3
506
Ancona, Bergamo, Catania, Milan, Naples, Padova, Prato
2021-06-22
Active, closed
Merck Sharp & Dohme LLC
Phase 3
342
Rome, Milan, Monza, Rozzano, Bari, Catania, Naples, Padova
2021-06-18
Active, closed
Janssen Research & Development, LLC
Phase 3
1,054
Catania, Milan, Naples, Palermo, Rome, Torino, Verona
2021-06-17
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
520
Bologna, Milan, Pisa, Roma
2021-06-15
Recruiting
Stereotactic Body Radiotherapy in Patients With Rare Oligometastatic Cancers (OligoRARE)
NCT04498767Gynecologic Cancer, Skin Cancer, Head and Neck Cancer, Sarcoma
European Organisation for Research and Treatment of Cancer - EORTC
Not applicable
200
Milan
2021-06-10
Active, closed
Galecto Biotech AB
Phase 2
21
Bologna, Florence, Milan, Orbassano, Varese
2021-06-09
Recruiting
Activation of Biobank Registry for Bilio-pancreatic Diseases
NCT06552078Pancreatitis, Pancreatic Disease, Non-Neoplastic Pancreatic Disorder, Pancreatic Adenocarcinoma
IRCCS San Raffaele
Observational
2,000
Milan
2021-06-09
Recruiting
Istituto Auxologico Italiano
Not applicable
8
Milan
2021-06-07
Active, closed
HistoSonics, Inc.
Not applicable
24
Milan
2021-06-04
Active, closed
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Observational
1,000
Milan
2021-06-03
Recruiting
Istituto Auxologico Italiano
Not applicable
60
Milan
2021-06-03
Active, closed
Ionis Pharmaceuticals, Inc.
Phase 3
54
Milan, Roma
2021-06-01
Recruiting
Observational Study on Skeletal Ewing's Sarcoma
NCT04845893Ewing Sarcoma of Bone
Italian Sarcoma Group
Observational
100
Rozzano, Aviano, Candiolo, Bari, Bologna, Florence, Genova, Milan
2021-06-01
Active, closed
Patient Reported Experience in Endoscopic Ultrasound
NCT05014347Pancreatic Diseases, Bile Duct Diseases
IRCCS San Raffaele
Observational
171
Milan
2021-06-01
Recruiting
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
NCT04895709Cervical Cancer, Gastric/Gastroesophageal Junction Adenocarcinoma, Microsatellite Stable Colorectal Cancer, Non-Small-Cell Lung Cancer
DrugsImzokitug·Pumitamig·Docetaxel·Nivolumab
Bristol-Myers Squibb
Phase 1/2
1,109
Rozzano, Candiolo, Milan, Naples, Roma, Siena
2021-05-27
Recruiting
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
NCT04844606Ulcerative Colitis, Ulcerative Colitis Chronic, Inflammatory Bowel Diseases, Crohn's Disease
DrugMirikizumab
Eli Lilly and Company
Phase 3
150
Bergamo, Bologna, Florence, Milan, Roma, Rome
2021-05-26
Recruiting
Poor Grade Aneurysmal Subarachnoid Hemorrhage Study Group
NCT04945603Subarachnoid Hemorrhage, Aneurysmal, Poor Grade Subarachnoid Hemorrhage
IRCCS San Raffaele
Observational
800
Bergamo, Bologna, Brescia, Lecce, Milan, Novara, Parma, Roma
2021-05-25
Recruiting
A Study of BGB-11417 in Participants With Myeloid Malignancies
NCT04771130Acute Myeloid Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasm
DrugsPosaconazole·Sonrotoclax·Azacitidine
BeOne Medicines
Phase 1/2
260
Bologna, Meldola, Milan
2021-05-24
Active, closed
Daiichi Sankyo
Phase 3
490
Barone, Candiolo, Catanzaro, Milan, Modena, Naples, Padua, Pisa
2021-05-21
Recruiting
Liver Embolization Approaches for Tumor Management
NCT05714124Hepatocellular Carcinoma, Cholangiocarcinoma, Metastatic Colon Cancer, Metastatic Cancer
IRCCS San Raffaele
Observational
580
Milan
2021-05-21
Recruiting
ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES
NCT04503395Aortic Aneurysm, Abdominal
FCRE (Foundation for Cardiovascular Research and Education)
Not applicable
204
Bologna, Genova, Milan, Perugia, Turin, Verona
2021-05-21
Active, closed
Bristol-Myers Squibb
Phase 3
681
Cremona, Florence, Meldola, Milan, Padova, Parma, Pavia, Roma
2021-05-21
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
210
Milan
2021-05-19
Active, closed
CNS Pharmaceuticals, Inc.
Phase 2
252
Bologna, Milan
2021-05-18
Active, closed
Merck Sharp & Dohme LLC
Phase 3
815
Monza, Milan, Rome, Naples
2021-05-12
Active, closed
Incyte Corporation
Phase 3
899
Bergamo, Brescia, Candiolo, Catania, Forlì, Genoa, Lecce, Milan
2021-05-11
Active, closed
Alfasigma S.p.A.
Observational
1,304
Bari, Brescia, Catania, Ferrara, Genova, Milan, Naples, Roma
2021-05-11
By invitation
Cytokinetics
Phase 2/3
900
Florence, Milan, Naples, Pisa, Roma, Trieste
2021-05-06
Active, closed
Hoffmann-La Roche
Phase 2
586
Naples, Salerno, Bologna, Rome, Genoa, Brescia, Milan, Pozzilli (IS)
2021-05-05
Active, closed
Hoffmann-La Roche
Phase 3
1,188
Avellino, Naples, Modena, Aviano, Rome, Brescia, Milan, Livorno
2021-05-04
Active, closed
Murdoch Childrens Research Institute
Not applicable
906
Monza, Varese, Florence, Milan, Rome
2021-05-04
Active, closed
Hoffmann-La Roche
Phase 3
761
Naples, Bologna, Meldola, Rome, Genoa, Milan, Orbassano, Arezzo
2021-05-03
Recruiting
IRCCS San Raffaele
Observational
100
Milan
2021-05-01
Active, closed
Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination
NCT04868877Non-Small Cell Lung Cancer Metastatic, Gastric Cancer, Esophageal Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma
DrugsBispecific·Tagrisso·Osimertinib
Merus B.V.
Phase 1/2
194
Roma, Bologna, Brescia, Milan, Orbassano, Salerno, Verona
2021-04-28
Active, closed
AstraZeneca
Phase 3
1,157
Bergamo, Candiolo, Genova, Livorno, Milan, Naples, Padova, Rozzano
2021-04-26
Recruiting
Alnylam Pharmaceuticals
Observational
150
Milan, Modena
2021-04-26
Active, closed
Hoffmann-La Roche
Phase 3
557
Naples, Bologna, Rome, Milan, Turin, Palermo, Florence, Pisa
2021-04-26
Recruiting
RESTORE - Study of AGN1 LOEP to Prevent Secondary Hip Fractures
NCT04796350Fragility Fracture, Hip Fractures, Osteoporosis
AgNovos Healthcare, LLC
Not applicable
2,400
Florence, Milan, Rome, Torino
2021-04-24
Recruiting
European Institute of Oncology
Not applicable
18
Milan
2021-04-23
Active, closed
Sarepta Therapeutics, Inc.
Observational
205
Genoa, Padova, Milan
2021-04-22
Recruiting
LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve
NCT04752722Superficial Bladder Cancer, Non-muscle Invasive Bladder Cancer With Carcinoma in Situ, Non-muscle Invasive Bladder Cancer
DrugPhase 2
enGene, Inc.
Phase 1/2
350
Milan, Naples, Rome, Torino
2021-04-22
Active, closed
Merck Sharp & Dohme LLC
Phase 3
808
Milan, Pozzuoli, Orbassano, Verona, Ancona, Catania, Padova
2021-04-21
Active, closed
Incyte Corporation
Phase 3
654
Bari, Brescia, Candiolo, Catania, Lecce, Milan, Naples, Novara
2021-04-15
Recruiting
Tendyne European Experience Registry
NCT04898335Mitral Regurgitation
LMU Klinikum
Observational
400
Milan, Pisa
2021-04-15
Active, closed
Merck Sharp & Dohme LLC
Phase 3
1,688
Modena, Rome, Bari, Milan, Naples, Terni
2021-04-14
Active, closed
Eli Lilly and Company
Phase 3
101
Naples, Genoa, Milan, Florence, Brescia
2021-04-13
Active, closed
Geron Corporation
Phase 3
327
Alessandria, Bologna, Cona, Florence, Genova, Milan, Ravenna, Reggio Calabria
2021-04-12
Active, closed
Phase 3 Study of Pelabresib (CPI-0610) in Myelofibrosis (MF) (MANIFEST-2)
NCT04603495Myelofibrosis, Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis
DrugsPelabresib·Ruxolitinib
Novartis Pharmaceuticals
Phase 3
430
Bergamo, Bologna, Brescia, Ferrara, Florence, Meldola, Milan, Monza
2021-04-09
Recruiting
Ospedale San Raffaele
Observational
40
Milan
2021-04-08
Active, closed
Loxo Oncology, Inc.
Phase 3
500
Alessandria, Meldola, Ravenna, Milan, Bologna, Genova, Palermo, Potenza
2021-04-08
Recruiting
Gilead Sciences
Phase 1
30
Milan, Naples
2021-04-06
Recruiting
Efficacy and Safety of Nemtabrutinib (MK-1026) in Participants With Hematologic Malignancies (MK-1026-003)
NCT04728893Hematologic Malignancies, Waldenstroms Macroglobulinaemia, Non-Hodgkins Lymphoma, Chronic Lymphocytic Leukaemia
DrugNemtabrutinib
Merck Sharp & Dohme LLC
Phase 2
490
Bari, Bologna, Brescia, Milan, Naples, Pavia, Reggio Emilia, Roma
2021-04-05
Recruiting
Italian Sarcoma Group
Observational
300
Bologna, Milan, Rozzano, Palermo, Aviano, Prato, Roma, Candiolo
2021-04-02
Active, closed
Novo Nordisk A/S
Phase 3
1,205
Catanzaro, San Giovanni Rotondo, Palermo, Bologna, Florence, Foggia, Milan, Roma
2021-04-01
Active, closed
Gruppo Oncologico del Nord-Ovest
Phase 2
31
Milan
2021-04-01
Active, closed
Kedrion S.p.A.
Phase 3
30
Brescia, Florence, Genova, Milan, Naples, Roma
2021-03-31
Recruiting
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
NCT04786262Diabetes Mellitus, Type 1, Impaired Hypoglycemic Awareness, Severe Hypoglycemia
DrugZimislecel
Vertex Pharmaceuticals Incorporated
Phase 3
57
Milan
2021-03-29
Active, closed
Hoffmann-La Roche
Phase 3
751
Chieti, Bari, Naples, Rome, Genoa, Milan, Montichiari, Pavia
2021-03-24
Recruiting
Guerbet
Phase 4
2,076
Siena, Trieste, Milan, Roma, Verona
2021-03-24
Active, closed
EMN Trial Office S.r.l. Impresa Sociale
Phase 2
50
Bari, Milan, Perugia, Roma, Trieste, Udine
2021-03-21
Active, closed
Hoffmann-La Roche
Phase 3
746
Foggia, Naples, Parma, Rome, Bergamo, Milan, Mondovì (CN), Catania
2021-03-17
Recruiting
Fondazione EMN Italy Onlus
Observational
1,900
Florence, Ancona, Bari, Bologna, Brescia, Catania, Genova, Milan
2021-03-16
Active, closed
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
206
Milan
2021-03-16
Recruiting
Subthreshold Laser Treatment for Reticular Pseudodrusen Secondary to Age-related Macular Degeneration
NCT04847635Macular Degeneration, Senile, Laser Burn of Retina, Macular Degeneration Intermediate, Macular Degeneration, Dry
Ospedale San Raffaele
Not applicable
50
Genova, Milan, Rome
2021-03-16
Active, closed
Karyopharm Therapeutics Inc
Phase 3
353
Catania, Meldola, Genova, Milan, Monza, Novara, Rionero in Vulture, Roma
2021-03-11
Recruiting
AstraZeneca
Phase 1
304
Milan, Monza, Naples, Padova
2021-03-09
Recruiting
Syndax Pharmaceuticals
Phase 2
296
Brescia, Milan, Monza, Pavia, Roma, Torino
2021-03-04
Recruiting
Longitudinal Study of Ultra-rare Inherited Metabolic and Degenerative Neurological Diseases.
NCT04880356Inherited Disease, Rare Diseases, Metabolic Disease, Undiagnosed Disease
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Observational
100
Milan
2021-03-01
Active, closed
German CLL Study Group
Phase 3
897
Catania, Ferrara, Mestre, Milan, Perugia, Roma, Torino
2021-03-01
Recruiting
Epithelioid Haemangioendothelioma Observational Study
NCT06680401Clinical Presentation, Natural History, Treatment Outcomes
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Observational
50
Milan
2021-02-25
Active, closed
Celgene
Phase 3
313
Meldola (fc), Ancona, Bologna, Brescia, Catania, Florence, Milan, Napoli Campania
2021-02-25
Active, closed
Merck Sharp & Dohme LLC
Phase 3
747
Meldola, Rozzano, Orbassano, Arezzo, Bari, Milan, Pavia, Roma
2021-02-25
Recruiting
Treosulfan Therapeutic Drug Monitoring in Pediatric Hematopoietic Stem Cell Transplant Recipients
NCT06861257Pediatric Hematopoietic Stem Cell Transplantation, Malignant Disorders, Non-malignant Disorders
Fondazione IRCCS Policlinico San Matteo di Pavia
Observational
70
Bologna, Brescia, Genova, Milan, Monza, Padova, Pavia, Torino
2021-02-24
Active, closed
Study of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation
NCT04699188KRAS G12C Mutant Solid Tumors, Carcinoma, Non-Small-Cell Lung, Carcinoma, Colorectal, Cancer of Lung
DrugsTNO155·Opnurasib·Tislelizumab
Novartis Pharmaceuticals
Phase 1/2
344
Brescia, Milan
2021-02-24
Recruiting
Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL
NCT04502394Diffuse Large B Cell Lymphoma, Chronic Lymphocytic Leukemia, Non Hodgkin Lymphoma
DrugsNavtemadlin·Acalabrutinib
Kartos Therapeutics, Inc.
Phase 1/2
84
Aviano, Meldola, Milan, Pavia, Verona
2021-02-23
Active, closed
Bioverativ, a Sanofi company
Phase 3
261
Naples, Milan, Vicenza
2021-02-23
Active, closed
Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms
NCT04279847Myelofibrosis, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasm Overlap Syndrome, Myeloproliferative Neoplasm
DrugRuxolitinib
Incyte Corporation
Phase 1
140
Bologna, Florence, Meldola, Milan, Orbassano, Verona
2021-02-23
Recruiting
Biosense Webster, Inc.
Observational
8,000
Acquaviva delle Fonti, Ancona, Milan, Naples
2021-02-22
Recruiting
Centro Cardiologico Monzino
Observational
10,000
Milan, Ancona, Bari, Bergamo, Brescia, Foggia, Naples, Palermo
2021-02-10
Active, closed
Fondazione Melanoma Onlus
Phase 2
25
Bergamo, Bagno a Ripoli, Meldola, Milan, Naples, Padova, Brescia
2021-02-10
Active, closed
Casting vs Bracing for Idiopathic Early-Onset Scoliosis
NCT04500041Scoliosis Idiopathic, Early-Onset Scoliosis Deformity of Spine
University of Iowa
Not applicable
71
Milan
2021-02-09
Recruiting
Antimicrobial Combination Therapy for Treatment of Enterococcus Faecalis Bacteremia
NCT06833593Enterococcus Faecalis Infection, Blood Stream Infection, Gut Microbiomes
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
510
Bologna, Catanzaro, Milan
2021-02-06
Active, closed
Hoffmann-La Roche
Phase 3
55
Naples, Parma, Milan, Florence
2021-02-04
Recruiting
AB Science
Phase 3
495
Baggiovara, Brescia, Gussago, Milan, Novara, Padova, Pavia, Torino
2021-02-02
Active, closed
HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer
NCT04619004Non-Small Cell Lung Cancer Metastatic, Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor
DrugPatritumab deruxtecan
Daiichi Sankyo
Phase 2
277
Parma, Orbassano, Meldola, Milan, Rozzano
2021-02-02
Recruiting
Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study
NCT04761120Mitral Regurgitation, Tricuspid Regurgitation, Valvular Heart Disease
Abbott Medical Devices
Observational
550
Bologna, Milan, Turin
2021-02-01
Recruiting
SCAD : a Registry of Spontaneous Coronary Artery Dissection
NCT06601270Spontaneous Coronary Artery Dissection
European Society of Cardiology
Observational
1,500
Bergamo, Foggia, Genoa, Mantua, Milan, Monza
2021-01-30
Active, closed
AstraZeneca
Phase 3
1,371
Bergamo, Florence, Milan, Modena, Naples, Novara, Padova, Parma
2021-01-28
Active, closed
IRCCS San Raffaele
Observational
322
Milan
2021-01-24
Recruiting
Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma
NCT04031677Retroperitoneal Sarcoma, Liposarcoma, Leiomyosarcoma
European Organisation for Research and Treatment of Cancer - EORTC
Phase 3
250
Aviano, Candiolo, Meldola, Milan, Padova, Roma
2021-01-20
Active, closed
Hoffmann-La Roche
Phase 2
920
Rome, Brescia, Milan, Turin, Siena
2021-01-18
Active, closed
Pfizer
Phase 3
257
Udine, Milan, San Sisto, Roma, Rome, Siena, Candiolo, Bari
2021-01-15
Active, closed
Radiomics and Molecular Classification in Endometrial Cancer
NCT06963385Endometrial Cancer, Uterine Cancer, Endometrium Tumor
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Not applicable
250
Milan
2021-01-15
Active, closed
Toralf Reimer, MD PhD
Not applicable
350
Milan
2021-01-13
Active, closed
Genmab
Phase 3
483
Bari, Bergamo, Brescia, Meldola, Milan, Novara, Pavia, Ravenna
2021-01-13
Active, closed
Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations
NCT04579380Uterine Neoplasms, Uterine Cervical Neoplasms, Biliary Tract Neoplasms, Urologic Neoplasms
DrugsTucatinib·Herceptin·Fulvestrant·Trastuzumab
Seagen, a wholly owned subsidiary of Pfizer
Phase 2
217
Milan
2021-01-11
Active, closed
Merck Sharp & Dohme LLC
Phase 3
990
Roma, Rome, Milan, Candiolo, Brescia, Naples, Padova
2021-01-10
Active, closed
BioNTech SE
Phase 2/3
358
Brescia, Legnago, Milan
2021-01-07
Active, closed
Amgen
Phase 1/2
181
Bergamo, Bologna, Brescia, Catania, Milan, Naples, Roma
2021-01-04
Active, closed
IRCCS San Raffaele
Observational
1,100
Milan
2021-01-01
Recruiting
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Phase 1/2
27
Milan, Padova, Pisa
2021-01-01
Active, closed
Istituto Clinico Humanitas
Observational
320
Milan
2021-01-01
Active, closed
A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations
NCT04639219Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
DrugTrastuzumab deruxtecan
AstraZeneca
Phase 2
102
Milan, Naples
2020-12-30
Active, closed
AstraZeneca
Phase 1/2
245
Bologna, Milan, Naples, Rome
2020-12-28
Active, closed
Daiichi Sankyo
Phase 3
605
Bologna, Catania, Genova, Milan, Orbassano, Roma
2020-12-21
Active, closed
Pfizer
Phase 3
841
Monserrato (CA), San Giovanni Rotondo, Milan, Candiolo, Orbassano, Brescia, Naples, Padova
2020-12-21
Active, closed
Stryker Neurovascular
Observational
405
Florence, Genova, Milan, Rome
2020-12-21
Active, closed
Verastem, Inc.
Phase 2
225
Milan, Padova
2020-12-21
Active, closed
Janssen Research & Development, LLC
Phase 2
220
Bari, Florence, Genova, Milan, Pisa, Roma, Rome, Torino
2020-12-18
Active, closed
Mirum Pharmaceuticals, Inc.
Phase 2
182
Bologna, Milan, Monza, Naples, Padova
2020-12-18
Active, closed
Neurocrine Biosciences
Phase 3
182
Ancona, Bologna, Florence, Messina, Milan, Naples, Padova, Roma
2020-12-16
Active, closed
ACURATE neo2™ Post Market Clinical Follow up Study
NCT04655248Aortic Valve Stenosis, Aortic Valve Calcification, Aortic Diseases
Boston Scientific Corporation
Observational
250
Catania, Milan, Pisa
2020-12-16
Active, closed
Atrasentan in Patients With IgA Nephropathy
NCT04573478IgA Nephropathy, Immunoglobulin A Nephropathy
DrugsAtrasentan·Zigakibart
Novartis Pharmaceuticals
Phase 3
404
Milan, Genova, Naples, Pavia
2020-12-11
Active, closed
GlaxoSmithKline
Phase 2/3
758
Ancona, Avellino, Florence, Milan, Monza, Naples, Orbassano to, Perugia
2020-12-08
Active, closed
Merck Sharp & Dohme LLC
Phase 3
672
Modena, Florence, Verona, Brescia, Milan, Padova, Roma
2020-12-08
Active, closed
Janssen Research & Development, LLC
Phase 3
518
Arezzo, Candiolo, Carpi, Catania, Foggia, Genova, Lugo, Milan
2020-12-07
Active, closed
MeiraGTx Ocular UK Ltd
Phase 3
97
Florence, Milan, Naples, Rome
2020-12-04
Active, closed
Amgen
Phase 3
135
Florence, Milan, Pisa, Reggio Emilia, Torino, Verona
2020-12-04
Active, closed
Daiichi Sankyo
Phase 3
1,600
Catania, Milan, Ancona, Aviano, Bari, Belluno, Bologna, Brindisi
2020-12-04
Active, closed
Predicting Parkinson's Disease Before It Strikes: A Brain Imaging Study in At-Risk Individual
NCT07729748Idiopathic REM Sleep Behavior Disorder, Parkinson Disease, Neurodegeneration, Prodromal Parkinson Disease
IRCCS San Raffaele
Observational
100
Milan
2020-12-04
Active, closed
Hoffmann-La Roche
Phase 3
769
Naples, Rome, Gallarate, Milan, Pavia, Turin
2020-12-03
Active, closed
Fondazione Melanoma Onlus
Phase 2
95
Bagno a Ripoli, Meldola, Milan, Naples, Padova, Genova
2020-12-03
Recruiting
Psychological and Psychiatric Assessment in Patients Eligible for Epilepsy Surgery
NCT06792383Focal Epilepsy With and Without Secondary Generalization
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Not applicable
180
Milan
2020-12-02
Active, closed
International Extranodal Lymphoma Study Group (IELSG)
Observational
496
Alessandria, Ponderano, Cagliari, Catania, Milan, Palermo, Padova, Pescara
2020-12-01
Active, closed
PARADIGM: Amplatzer Valvular Plug for PVL Closure
NCT04489823Paravalvular Aortic Regurgitation
Abbott Medical Devices
Not applicable
200
Milan
2020-12-01
Recruiting
Prospective Registry Of Therapeutic EndoscopiC ulTrasound
NCT04813055Gastric Outlet Obstruction, Biliary Obstruction, Acute Pancreatic Fluid Collection, Acute Pancreatitis With Infected Necrosis
Paolo Giorgio Arcidiacono, MD
Observational
510
Milan
2020-12-01
Active, closed
Hoffmann-La Roche
Phase 3
864
Chieti, Naples, Rome, Milan, Pozzilli
2020-11-26
Active, closed
Eli Lilly and Company
Phase 3
312
Milan, Roma
2020-11-25
Active, closed
Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome
NCT04623541Relapsed/Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Richter's Syndrome, Treatment-naïve High Risk Chronic Lymphocytic Leukemia
DrugsEpcoritamab·Pirtobrutinib·Lenalidomide·Venetoclax
Genmab
Phase 1/2
194
Bologna, Torino, Ferrara, Meldola, Rome, Roma, Brescia, Milan
2020-11-25
Recruiting
Alnylam Pharmaceuticals
Observational
1,500
Milan, Naples, Palermo, Roma
2020-11-23
Recruiting
Resorbable Magnesium Scaffolds Registry
NCT04679740Coronary Artery Disease
Biotronik AG
Observational
1,106
Milan
2020-11-18
Active, closed
Janssen Pharmaceutica N.V., Belgium
Phase 3
691
Bologna, Florence, Milan, Roma
2020-11-12
Active, closed
AstraZeneca
Phase 1/2
702
Milan, Modena, Naples, Padova, Roma
2020-11-12
Active, closed
AbbVie
Phase 1
21
Milan
2020-11-11
Active, closed
Bayer
Phase 4
654
Ferrara, Modena, Parma, Aviano, Rome, Genoa, Milan, Alessandria
2020-11-09
Recruiting
Meril Life Sciences Pvt. Ltd.
Not applicable
988
Bologna, Catania, Milan, Tortona, Turin
2020-11-04
Active, closed
Associazione Italiana per lo Studio del Pancreas
Phase 3
261
Aviano, Bari, Bergamo, Bologna, Brescia, Florence, Meldola, Milan
2020-11-03
Active, closed
Genmab
Phase 1/2
543
Bergamo, Bologna, Candiolo, Meldola, Milan, Pavia, Reggio Emilia
2020-11-03
Recruiting
Istituto Auxologico Italiano
Observational
300
Milan
2020-11-02
Recruiting
CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry
NCT04688190Mitral Regurgitation, Mitral Valve Disease, Mitral Annular Calcification
Universitätsklinikum Hamburg-Eppendorf
Observational
1,000
Brescia, Milan, Pisa
2020-11-01
Active, closed
Novartis Pharmaceuticals
Phase 2
134
Milan, Naples
2020-10-30
Recruiting
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
NCT04585750Advanced Solid Tumor, Advanced Malignant Neoplasm, Metastatic Cancer, Metastatic Solid Tumor
DrugsRezatapopt·Keytruda·Pembrolizumab
PMV Pharmaceuticals, Inc
Phase 1/2
300
Rome, Milan, Rozzano, Candiolo, Naples
2020-10-29
Recruiting
Occlutech International AB
Observational
150
Florence, Milan
2020-10-28
Recruiting
IFOM ETS - The AIRC Institute of Molecular Oncology
Observational
500
Genova, Milan, Padua, Pisa, Candiolo, Orbassano, Torino
2020-10-28
Active, closed
Hoffmann-La Roche
Phase 3
985
Naples, Parma, Rome, Genoa, Milan, Montichiari, Pozzilli, Palermo
2020-10-26
Recruiting
Abbott Vascular Medical Device Registry
NCT04573660Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism
Abbott Medical Devices
Observational
3,784
Milan, San Donato Milanese
2020-10-25
Active, closed
Exelixis
Phase 3
575
Meldola, Rozzano, Sondrio, Trento, Ancona, Florence, Milan, Parma
2020-10-19
Recruiting
Diagnosis; Objective RespOnse; THErApy
NCT05036564Primary CNS Lymphoma
IRCCS San Raffaele
Not applicable
70
Milan
2020-10-16
Active, closed
Myasthenia Gravis Inebilizumab Trial
NCT04524273Myasthenia Gravis
DrugInebilizumab
Amgen
Phase 3
238
Milan, Pavia, Rome
2020-10-15
Active, closed
Janssen Research & Development, LLC
Phase 3
308
Bologna, Catania, Meldola, Milan, Monza, Ravenna, Roma, Rozzano
2020-10-13
Recruiting
CT-based Myocardial Characterization (CTMyoC)
NCT06029400Cardiovascular Diseases
IRCCS San Raffaele
Observational
2,200
Milan
2020-10-12
Active, closed
Hoffmann-La Roche
Phase 3
992
Meldola, Rome, Brescia, Milan, Monza, Misterbianco (CT), Candiolo, Livorno
2020-10-09
Active, closed
Acerta Pharma BV
Phase 3
611
Bari, Bergamo, Bologna, Florence, Genova, Meldola, Milan, Novara
2020-10-08
Recruiting
Voluntary Activation During Isokinetic Contractions in Subjects with Neuromotor Disorders
NCT04607174Multiple Sclerosis, Poststroke/CVA Hemiparesis, Parkinson Disease, Knee Impairment
Istituto Auxologico Italiano
Not applicable
20
Milan
2020-10-07
Recruiting
Genetic Landscape in Women with Metastatic Ovarian Cancer Before and During Treatment with PARP Inhibitors
NCT06785077Leukemia, Myeloid, Acute, Myeloid Dysplasia, Ovarian Epithelial Cancer
European Institute of Oncology
Not applicable
157
Milan
2020-10-02
Active, closed
AstraZeneca
Phase 3
370
Brescia, Candiolo, Florence, Milan, Modena, Naples, Padova
2020-10-02
Active, closed
A Gene Transfer Study for Late-Onset Pompe Disease (RESOLUTE)
NCT04093349Pompe Disease, Pompe Disease (Late-onset), Glycogen Storage Disease Type 2, Glycogen Storage Disease Type II
Spark Therapeutics, Inc.
Phase 1/2
4
Messina, Milan, Naples, Pisa, Torino
2020-10-01
Active, closed
GlaxoSmithKline
Phase 3
302
Bologna, Milan, Pavia, Roma
2020-10-01
Active, closed
AbbVie
Phase 3
527
Bologna, Genoa, Milan, Rho, Rome, Negrar, Cagliari, Palermo
2020-09-30
Active, closed
Hoffmann-La Roche
Phase 3
190
Ravenna, Rome, Milan, Turin, Florence
2020-09-30
Active, closed
Janssen Research & Development, LLC
Phase 3
1,074
Avellino, Catania, Meldola, Milan, Monza, Naples, Orbassano, Ravenna
2020-09-30
Recruiting
Liquid Biospy for Urinary Cancers
NCT06116396Urothelial Carcinoma
IRCCS San Raffaele
Observational
450
Milan
2020-09-29
Active, closed
Ipsen
Phase 3
161
Modena, Bologna, Milan, Monza, Padova, Palermo
2020-09-24
Active, closed
Janssen Research & Development, LLC
Phase 3
696
Arezzo, Candiolo, Cremona, Lecce, Meldola, Milan, Naples, Orbassano
2020-09-23
Active, closed
argenx
Phase 2
229
Brescia, Florence, Genova, Messina, Milan, Pisa, Roma, Torino
2020-09-18
Active, closed
Janssen Research & Development, LLC
Phase 2
194
Bergamo, Bologna, Milan
2020-09-17
Active, closed
ADC Therapeutics S.A.
Phase 3
440
Udine, Brescia, Florence, Foggia, Meldola, Milan, Pavia, Ravenna
2020-09-16
Active, closed
Daiichi Sankyo
Phase 1
145
Milan, Monza, Naples
2020-09-15
Active, closed
Mario Negri Institute for Pharmacological Research
Observational
1,200
Milan
2020-09-15
Recruiting
BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours
NCT04421820Colorectal Cancer, Pancreatic Cancer, Gastric Cancers, Cholangiocarcinoma
DrugsFolfox·Oxaliplatin
Bold Therapeutics, Inc.
Phase 1/2
220
Milan, Naples, Pisa
2020-08-28
Active, closed
Seagen, a wholly owned subsidiary of Pfizer
Phase 3
239
Bari, Tricase, Milan, Bologna, Trieste
2020-08-20
Active, closed
A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors
NCT04482309Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer, Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer
DrugTrastuzumab deruxtecan
AstraZeneca
Phase 2
477
Milan, Naples, Rome
2020-08-18
Recruiting
Meril Life Sciences Pvt. Ltd.
Observational
200
Milan
2020-08-07
Active, closed
AstraZeneca
Phase 3
185
Ancona, Bologna, Brescia, Candiolo, Catania, Lecce, Lecco, Milan
2020-08-04
Active, closed
Incyte Corporation
Phase 2
112
Bologna, Florence, Meldola (FC), Milan, Naples, Novara, Palermo, Pisa
2020-08-03
Active, closed
Medtronic
Observational
2,200
Bologna, Cosenza, Lecce, Milan, Taranto, Udine
2020-08-01
Active, closed
Medtronic
Observational
2,200
Bologna, Castrovillari, Lecce, Milan, Taranto, Udine
2020-08-01
Active, closed
Genentech, Inc.
Phase 1
498
Meldola, Milan, Rozzano (MI), Pisa
2020-07-29
Active, closed
AstraZeneca
Phase 3
866
Aviano, Bergamo, Candiolo, Cona, Genova, Livorno, Messina, Milan
2020-07-24
Active, closed
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies
NCT04561362Urinary Bladder Neoplasm, Triple Negative Breast Neoplasms, Hormone Receptor Positive, HER2-negative Neoplasms, Hormone Receptor Positive, HER2-low Neoplasms
DrugsZelenectide pevedotin·Keytruda·Pembrolizumab
BicycleTx Limited
Phase 1/2
329
Milan
2020-07-17
Recruiting
IFOM ETS - The AIRC Institute of Molecular Oncology
Observational
1,500
Bergamo, Milan, Novara, Padova, Pavia, Roma, Reggio Emilia
2020-07-16
Recruiting
Multimodality Treatments of HPV-related Lesions of the Female Genital Tract
NCT05938192HPV, Cervical Cancer, Cervix Lesion, Vagina Disease
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Observational
200
Milan
2020-07-15
Recruiting
Recurrent Ovarian CarcinoSarcoma Anti-pd-1 Niraparib
NCT03651206Ovarian Carcinosarcoma, Endometrial Carcinosarcoma
DrugNiraparib
ARCAGY/ GINECO GROUP
Phase 2/3
138
Bologna, Catania, Meldola, Milan, Naples, Roma, Torino
2020-07-15
Active, closed
GlaxoSmithKline
Phase 3
242
Milan, Modena, Monza, Naples, Negrar Verona, Padova, Palermo, Roma
2020-07-14
Recruiting
IRCCS Policlinico S. Donato
Observational
70
Milan
2020-07-13
Recruiting
IRCCS San Raffaele
Observational
586
Milan
2020-07-13
Active, closed
Baxalta now part of Shire
Observational
207
Milan, Roma
2020-07-09
Active, closed
Amplatzer Amulet LAAO vs. NOAC
NCT04226547Atrial Fibrillation, Stroke, Bleeding
DrugNOAC
Abbott Medical Devices
Not applicable
2,650
Massa, Milan
2020-07-07
Active, closed
Merck Sharp & Dohme LLC
Phase 3
870
Torrette, Rome, Rozzano, Florence, Lecce, Milan, Modena, Udine
2020-07-06
Active, closed
SELUTION SLR™ 014 In-stent Restenosis
NCT04280029Coronary Restenosis
M.A. Med Alliance S.A.
Not applicable
418
Cotignola, Milan, Padova
2020-07-06
Recruiting
European Institute of Oncology
Observational
40
Milan
2020-07-03
Recruiting
Altshock-2 REGISTRY
NCT04295252Cardiogenic Shock
Niguarda Hospital
Observational
3,000
Milan
2020-07-01
Recruiting
Safety and Early Signs of Efficacy of IL12-L19L19.
NCT04471987Advanced Solid Tumor, Metastatic Solid Tumor
Philogen S.p.A.
Phase 1
80
Milan, Orbassano
2020-07-01
Recruiting
NeVa ONE Registry Study
NCT04562194Acute Ischemic Stroke
Vesalio
Not applicable
600
Milan
2020-07-01
Active, closed
IRCCS San Raffaele
Observational
100
Milan
2020-07-01
Recruiting
Niguarda Hospital
Observational
26
Milan
2020-06-30
Active, closed
Actelion
Phase 3
935
Milan, Modena, Nuoro, Pavia, Pisa, Roma
2020-06-30
Active, closed
Shanghai Junshi Bioscience Co., Ltd.
Phase 3
530
Milan, Naples, Pisa, Tortona, Verona
2020-06-29
Recruiting
Efficacy and Safety of the CG-100 Intraluminal Bypass Device
NCT04184973Rectal Cancer, Rectal Tumor, Rectal/Anal
Colospan Ltd.
Not applicable
250
Milan
2020-06-23
Active, closed
Eli Lilly and Company
Phase 3
996
Milan, Rho
2020-06-22
Active, closed
Protection Against Emboli During Carotid Artery Stenting Using the Neuroguard IEP System
NCT04201132Carotid Artery Stenosis, Carotid Artery Diseases, Carotid Stenosis
Contego Medical, Inc.
Not applicable
305
Milan
2020-06-12
Active, closed
Janssen Research & Development, LLC
Phase 3
419
Bologna, Milan, Roma, Turin
2020-06-12
Active, closed
Eli Lilly and Company
Phase 1
71
Milan
2020-06-11
Active, closed
Epizyme, Inc.
Phase 3
599
Naples, Meldola, Brescia, Catania, Florence, Lecce, Milan, Monza
2020-06-11
Recruiting
RecruitmEnt Assessed by eleCtRical Impedance Tomography
NCT04460859Acute Respiratory Distress Syndrome (ARDS)
Unity Health Toronto
Observational
171
Milan
2020-06-09
Active, closed
AstraZeneca
Phase 2
452
Milan, Naples, Padova, Roma, Verona
2020-06-03
Recruiting
IRCCS San Raffaele
Observational
50
Milan
2020-06-01
Recruiting
SEarchiNg biomarkErs Cerebral Amyloid Angiopathy (SENECA)
NCT04204642Cerebral Amyloid Angiopathy
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Observational
500
Milan
2020-06-01
Recruiting
The Liver BIoBank Lombardia of Fatty Liver
NCT06566105NAFLD, Precision Medicine, Cardiovascular Diseases
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
2,500
Milan
2020-06-01
Active, closed
Gruppo Italiano Malattie EMatologiche dell'Adulto
Observational
572
Alessandria, Asti, Bari, Bologna, Cagliari, Florence, Milan, Modena
2020-05-29
Recruiting
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
NCT04256317Myelodysplastic Syndromes, Acute Myeloid Leukemia, Myelodysplastic Syndrome/Neoplasm, Chronic Myelomonocytic Leukemia
DrugsVenclexta·Azacitidine·Venetoclax
Taiho Oncology, Inc.
Phase 2/3
316
Ravenna, Florence, Torino, Bologna, Milan, Novara, Roma
2020-05-21
Recruiting
European Institute of Oncology
Phase 2
46
Milan
2020-05-20
Active, closed
Merck Sharp & Dohme LLC
Phase 3
520
Bari, Rome, Milan, Florence, Modena, Naples, Province of Macerata
2020-05-19
Active, closed
GlaxoSmithKline
Phase 3
494
Bergamo, Meldola FC, Milan, Siena
2020-05-07
Active, closed
AstraZeneca
Phase 2
240
Bologna, Catanzaro, Meldola, Messina, Milan, Monza, Naples, Roma
2020-04-22
Recruiting
The FUnctional TricUspid REgurgitation by 3D EChocardiography Cooperative Study
NCT05747404Heart Valve Incompetence, Echocardiography, Transthoracic
Istituto Auxologico Italiano
Observational
1,500
Milan, Padova
2020-04-21
Active, closed
AstraZeneca
Phase 3
818
Bergamo, Candiolo, Catanzaro, Livorno, Meldola, Milan, Modena, Naples
2020-04-16
Active, closed
GlaxoSmithKline
Phase 3
325
Bologna, Brescia, Catanzaro, Milan, Pavia, Perugia, Ravenna, Roma
2020-04-02
Active, closed
Astellas Pharma Global Development, Inc.
Phase 3
886
Areezo, Candiolo, Cremona, Genova, Meldola, Milan, Pisa, Terni
2020-03-30
Active, closed
BeOne Medicines
Phase 1
437
Milan, Perugia, Ravenna, Roma, Verona
2020-03-24
Active, closed
IRCCS San Raffaele
Observational
158
Milan
2020-03-19
Recruiting
Università Vita-Salute San Raffaele
Observational
6,000
Milan
2020-03-19
Recruiting
Early Detection of Advanced Adenomas and Colorectal Cancer
NCT06342440Colorectal Cancer, Colorectal Neoplasms, Colorectal Polyp, Colorectal Adenocarcinoma
City of Hope Medical Center
Observational
2,000
Milan
2020-03-15
Recruiting
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations
NCT04094610Locally Advanced Solid Tumors, Metastatic Solid Tumors, Lymphoma, Primary CNS Tumors
DrugRepotrectinib
Turning Point Therapeutics, Inc.
Phase 1/2
75
Milan, Padova, Rome, Torino
2020-03-12
Recruiting
TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention
NCT04294927BRCA1 Gene Mutation, BRCA2 Gene Mutation, RAD51C Gene Mutation, RAD51D Gene Mutation
University Medical Center Nijmegen
Not applicable
3,000
Bologna, Milan, Monza, Rome
2020-03-01
Recruiting
Global Approach to Faint and Falls
NCT05752682Syncope, Fall
Istituto Auxologico Italiano
Observational
340
Milan
2020-03-01
Active, closed
Merck Sharp & Dohme LLC
Phase 3
755
Verona, Arezzo, Bari, Bologna, Milan, Modena, Padova, Pavia
2020-02-27
Active, closed
Eli Lilly and Company
Phase 3
261
Naples, Ravenna, Aviano, Rome, Monza, Milan, Rozzano, Orbassano
2020-02-17
Active, closed
Eli Lilly and Company
Phase 3
58
Brescia, Chieti, Genova, Milan, Naples, Palermo, Trieste
2020-02-12
Active, closed
Loxo Oncology, Inc.
Phase 3
291
Naples, Rome, Milan, Turin, Pisa, Siena, Padova, Catania
2020-02-11
Active, closed
Long-term Follow-up Study of Patients Receiving Onasemnogene Abeparvovec-xioi
NCT04042025Spinal Muscular Atrophy Type I, Spinal Muscular Atrophy Type II, Spinal Muscular Atrophy Type III, SMA
DrugsOnasemnogene Abeparvovec-xioi·Zolgensma
Novartis Gene Therapies
Phase 3
85
Roma, Genova, Milan
2020-02-10
Recruiting
Efficacy of Split Gait in the Treatment of Dynamic Asymmetries in Subjects With Pathologic Claudication
NCT04635436Multiple Sclerosis, Poststroke/CVA Hemiparesis, Parkinson Disease, Amputation
Istituto Auxologico Italiano
Not applicable
20
Milan
2020-02-05
Recruiting
GMK Sphere TiNb Total Knee Arthroplasty PMS Study
NCT04801654Total Knee Arthroplasty
Medacta International SA
Observational
155
Milan
2020-02-05
Recruiting
Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors
NCT03934372Acute Myeloid Leukemia, Accelerated Phase Chronic Myeloid Leukemia, Blast Phase Chronic Myeloid Leukemia, Chronic Phase Chronic Myeloid Leukemia
DrugPonatinib
Incyte Biosciences International Sàrl
Phase 1/2
70
Bologna, Brescia, Genova, Milan, Monza, Naples, Pavia, Rome
2020-01-29
Active, closed
Hoffmann-La Roche
Phase 2/3
325
Parma, Brescia, Milan, Bagno a Ripoli, Padova
2020-01-29
Recruiting
Eli Lilly and Company
Phase 2
105
Bologna, Candiolo, Milan, Padova, Roma, Rozzano
2020-01-22
Active, closed
MitraClip EXPAND G4 Study
NCT04177394Mitral Valve Regurgitation, Mitral Regurgitation
Abbott Medical Devices
Observational
1,164
Milan, Catania
2020-01-17
Active, closed
BeOne Medicines
Phase 3
955
Bologna, Meldola, Milan, Modena, Novara, Ravenna, Roma, Terni
2020-01-16
Active, closed
Actelion
Phase 3
138
Bologna, Milan, Padova, Roma, S. Donato Milanese, Torino
2020-01-16
Recruiting
Comprehensive Aneurysm Management Trial
NCT04155606Saccular Aneurysm, Intracranial Aneurysm, Unruptured Cerebral Aneurysm
Centre hospitalier de l'Université de Montréal (CHUM)
Not applicable
2,000
Bergamo, Lecce, Milan
2020-01-15
Active, closed
Takeda
Phase 3
354
Naples, Meldola, Milan, Orbassano, Aviano, Pisa, Parma, Ravenna
2020-01-10
Active, closed
Advanced Accelerator Applications
Phase 3
226
Bologna, Genova, Meldola, Milan, Naples, Reggio Emilia, Roma
2020-01-08
Recruiting
The Role of Micrometastasis and Isolated Tumor Cells (ITCs) in Endometrial and Cervical Cancer. A Multicenter Study.
NCT04403867Endometrial Cancer, Cervical Cancer, Sentinel Lymph Node, Micrometastasis
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Observational
500
Milan
2020-01-02
Recruiting
FATAL-NSTI Study (Factors Associated With In-hospital mortALity in NSTI).
NCT07359651Necrotizing Fascitis, Fournier Gangrene, Fournier's Gangrene, Soft Tissue Infections
University of Cagliari
Observational
300
Cagliari, Milan, Monza, Roma
2020-01-01
Recruiting
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Observational
600
Milan
2020-01-01
Active, closed
USWM CT, LLC
Phase 2
103
Milan, Rozzano (MI)
2019-12-31
Recruiting
Merck Sharp & Dohme LLC
Phase 1/2
450
Florence, Milan, Roma
2019-12-19
Recruiting
Merck Sharp & Dohme LLC
Observational
1,065
Florence, Milan, Roma
2019-12-19
Active, closed
Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)
NCT04185883Advanced Solid Tumors, Kirsten Rat Sarcoma (KRAS) pG12C Mutation
DrugsBI 1701963·TNO155·Sotorasib·Afatinib
Amgen
Phase 1
610
Milan, Pisa, Verona
2019-12-17
Recruiting
Sumitomo Pharma America, Inc.
Phase 1/2
240
Alessandria, Aviano, Bologna, Brescia, Meldola, Milan, Torino
2019-12-16
Active, closed
Primary Unloading and Delayed Reperfusion in ST-Elevation Myocardial Infarction: The STEMI-DTU Trial
NCT03947619ST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Abiomed Inc.
Not applicable
527
Genoa, Milan, Verona, Rozzano
2019-12-12
Recruiting
Alexion Pharmaceuticals, Inc.
Observational
500
Milan, Naples
2019-12-02
Active, closed
LAM561 With RT and TMZ for Adults With Glioblastoma
NCT04250922Primary Glioblastoma, Glioblastoma Multiforme
DrugLAM561
Laminar Pharmaceuticals
Phase 2/3
144
Padova, Milan, Roma, Turin
2019-12-01
Recruiting
Abbott DBS Post-Market Study of Outcomes for Indications Over Time
NCT04071847Movement Disorders, Parkinson Disease, Essential Tremor, Tremor
Abbott Medical Devices
Observational
1,000
Cona, Rome, Milan
2019-11-26
Recruiting
fREEDOM: REsonance for Early Detection Of Breast Cancer Metastases
NCT06328465Invasive Breast Cancer, HER2-positive Breast Cancer, Triple Negative Breast Cancer
European Institute of Oncology
Not applicable
145
Milan
2019-11-22
Active, closed
Gilead Sciences
Phase 2/3
72
Bergamo, Brescia, Milan, Roma, Rome
2019-11-21
Recruiting
Paola Pisani
Not applicable
296
Milan
2019-11-19
Active, closed
Regeneron Pharmaceuticals
Phase 2
515
Milan, Bologna, Livorno, Novara, Perugia, Ravenna, Reggio Emilia, Varese
2019-11-13
Active, closed
Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors
NCT04082429Haemophilia A Without Inhibitors, Haemophilia B Without Inhibitors
DrugConcizumab
Novo Nordisk A/S
Phase 3
156
Florence, Milan, Roma, Torino
2019-11-13
Recruiting
Mpact 3D Metal Cup PMS
NCT04801680Total Hip Arthroplasty
Medacta International SA
Observational
500
Milan
2019-11-07
Active, closed
AbbVie
Phase 1/2
218
Bologna, Milan, Novara, Meldola
2019-11-06
Recruiting
Advanced Therapies for Liver Metastases
NCT04622423Pancreatic Ductal Adenocarcinoma (PDAC), Colorectal Cancer (CRC), Liver Metastasis, IPMN, Pancreatic
IRCCS San Raffaele
Observational
625
Milan
2019-11-06
Active, closed
Bristol-Myers Squibb
Phase 3
461
Forlì, Milan, Parma
2019-11-05
Recruiting
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
NCT04065399Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Mixed Lineage Acute Leukemia, Mixed Phenotype Acute Leukemia
DrugsCobicistat·Revumenib
Syndax Pharmaceuticals
Phase 1/2
447
Bologna, Meldola, Milan, Roma, Vicenza
2019-11-05
Active, closed
Pediatric Long-Term Follow-up and Rollover Study
NCT03975829Diffuse Astrocytoma, Anaplastic Astrocytoma, Astrocytoma, Oligodendroglioma, Childhood
DrugsDabrafenib·Trametinib
Novartis Pharmaceuticals
Phase 4
163
Florence, Genova, Milan, Roma, Torino
2019-11-04
Active, closed
Balt Extrusion
Observational
234
Milan, Monza, Treviso, Udine
2019-11-04
Recruiting
Norwegian University of Science and Technology
Phase 3
112
Milan
2019-11-01
Active, closed
A Phase 1/2 Trial of CLN-081 in Patients With Non-Small Cell Lung Cancer
NCT04036682Non Small Cell Lung Cancer, EGFR Exon 20 Mutation
DrugZipalertinib
Cullinan Therapeutics Inc.
Phase 1/2
284
Careggi, Marche, Meldola, Milan, Modena, Monza, Ravenna
2019-10-31
Recruiting
Italian Observational Study on CAR-T Therapy for Lymphoma
NCT06339255Diffuse Low Grade B-Cell Lymphoma, Primary Mediastinal Large B-cell Lymphoma (PMBCL), Mantle Cell Lymphoma, Follicular Lymphoma
Paolo Corradini
Observational
5,300
Milan
2019-10-30
By invitation
Rigel Pharmaceuticals
Phase 3
90
Milan, Novara
2019-10-30
Active, closed
Novartis Pharmaceuticals
Phase 1
120
Milan, Rozzano, Modena, Aviano, Siena, Naples
2019-10-30
Active, closed
AstraZeneca
Phase 3
140
Cuneo, Florence, Milan, Naples, Roma, Torino
2019-10-29
Active, closed
Bristol-Myers Squibb
Phase 3
790
Palermo, Bergamo, Milan, Naples, Padova, Perugia, Siena
2019-10-28
Recruiting
GlaxoSmithKline
Phase 1/2
184
Genova, Milan, Padova, Roma, Torino
2019-10-25
Active, closed
Nouscom SRL
Phase 1/2
115
Avellino, Candiolo, Milan, Siena
2019-10-21
Active, closed
Novo Nordisk A/S
Phase 3
134
Florence, Castelfranco Veneto, Milan, Udine, Verona
2019-10-21
Active, closed
Eli Lilly and Company
Phase 3
30
Milan, Florence
2019-10-16
Recruiting
ALFAOMEGA Master Observational Trial
NCT04120935Colorectal Cancer
IFOM ETS - The AIRC Institute of Molecular Oncology
Observational
3,000
Biella, Milan, Padova, Perugia, Pisa, Ravenna, Candiolo, Orbassano
2019-10-15
Recruiting
Study on Gynecological Rare Cancers
NCT05733806Gynecologic Cancer
National Cancer Institute, Naples
Observational
500
Milan, Naples
2019-10-14
Active, closed
PULSTA Transcatheter Pulmonary Valve Pre-Approval Study
NCT03983512Heart Diseases, Pulmonary Valve Regurgitation, Pulmonary Valve Stenosis, Tetralogy of Fallot
Taewoong Medical Co., Ltd.
Not applicable
58
Milan
2019-10-07
Active, closed
Niguarda Hospital
Phase 2
28
Alessandria, Bergamo, Bologna, Brescia, Milan, Novara, Pavia, Roma
2019-10-04
Active, closed
Seagen, a wholly owned subsidiary of Pfizer
Phase 3
466
Torrette, Bologna, Rome, Faenza, Lugo, Cattolica, Milan, Ravenna
2019-10-02
Recruiting
Niguarda Hospital
Observational
1,067
Milan
2019-10-01
Active, closed
NeuroDerm Ltd.
Phase 3
381
Arcugnano, Cassino, Chieti, Grosseto, Milan, Naples, Pavia, Roma
2019-09-30
Active, closed
Celgene
Phase 1/2
424
Brescia, Milan, Reggio Emilia, Torino
2019-09-30
By invitation
A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)
NCT04093570Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes
DrugDecitabine
Taiho Oncology, Inc.
Phase 2
332
Milan
2019-09-30
Active, closed
MALIBU Trial - Combination of Ibrutinib and Rituximab in Untreated Marginal Zone Lymphomas
NCT03697512Marginal Zone Lymphoma, Nodal Marginal Zone Lymphoma, Splenic Marginal Zone Lymphoma
DrugsIbrutinib·Rituximab
International Extranodal Lymphoma Study Group (IELSG)
Phase 2
175
Ponderano, Milan, Torino, Ancona, Bari, Brescia, Cagliari, Pavia
2019-09-27
Active, closed
Janssen Research & Development, LLC
Phase 2/3
1,064
Bologna, Milan, Negrar, Padova, Palermo, Rho, Roma, Rozzano
2019-09-26
By invitation
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
NCT03683186PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension
United Therapeutics
Phase 3
1,000
Palermo, Foggia, Genova, Milan, Monza, Pavia, Roma
2019-09-23
Recruiting
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
NCT04104776Advanced Solid Tumor, Diffuse Large B Cell Lymphoma, Lymphoma, T-Cell, Mesothelioma, Malignant
DrugsTulmimetostat·Enzalutamide
Novartis Pharmaceuticals
Phase 1/2
300
Bologna, Milan, Roma, Rozzano
2019-09-18
Active, closed
GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors
NCT04083599Malignant Solid Tumor, Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC), Melanoma
DrugsGEN1042·Adrucil·Nab-paclitaxel·Pemetrexed
Genmab
Phase 1/2
350
Brescia, Cuneo, Milan, Rozzano
2019-09-17
Active, closed
Pfizer
Phase 3
896
Castellana Grotte, Brescia, Milan, San Donato Milanese, Rho, Modena, Florence, Negrar(vr)
2019-09-05
Recruiting
68Ga-DOTATOC PET for the Evaluation of Gastroenteropancreatic Neuroendocrine Tumours
NCT06155318Gastroenteropancreatic Neuroendocrine Tumor
IRCCS San Raffaele
Observational
300
Milan
2019-09-05
Active, closed
Janssen Research & Development, LLC
Phase 1
701
Milan, Monza, Naples, Ravenna
2019-09-04
Not yet open
Hepatocarcinoma Recurrence on the Liver Study - Part2
NCT04053231Liver Cancer, Surgery, Recurrence Tumor, Cirrhosis
University of Milano Bicocca
Observational
3,000
Bari, Bologna, Bolzano, Brescia, Forlì, Lecco, Mantua, Milan
2019-09
Recruiting
Centro di Riferimento Oncologico - Aviano
Observational
78
Aviano, Genova, Messina, Milan, Modena, Naples, Reggio Emilia, Roma
2019-08-27
Active, closed
ETOP IBCSG Partners Foundation
Phase 3
405
Aviano, Bergamo, Brindisi, Meldola, Milan, Novara, Parma, Pavia
2019-08-27
Active, closed
MiCLASP Post Market Clinical Follow-Up (PMCF) Study
NCT04430075Mitral Regurgitation, Mitral Insufficiency
Edwards Lifesciences
Observational
1,000
Milan, Massa, San Donato Milanese
2019-08-23
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Priya Life Science (2026). Clinical trial register: studies with an Italian investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 11 October 2026. https://priyalifescience.com/clinical-trials-italy/city/milan?page=5

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Italy and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 6,791 studies in total at the last sync on 11 Oct 2026, 03:19 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 2,846 of those studies with a site in Milan.

How many clinical trials are recruiting in Milan?

1,595 of the 2,846 studies on this page are recruiting new participants as of the 11 Oct 2026, 03:19 UTC sync. A further 145 have not yet opened recruitment, 1,033 are active but closed to new participants, and 73 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.