Vorbipiprant is named as an intervention in 2 current clinical trials in our Italy register. 1 is recruiting patients now. The most common phase is Phase 1/2. The sponsor with the most trials is Rottapharm Biotech (1). The most-studied condition is Refractory Metastatic Colorectal Cancer.
| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)
NCT05845450 · ClinicalTrials.gov ↗ · Colorectal Cancer, Resectable Colorectal Carcinoma
|
Phase 2 | Recruiting | Gruppo Oncologico del Nord-Ovest | Italy |
|
Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers
NCT05205330 · ClinicalTrials.gov ↗ · Refractory Metastatic Colorectal Cancer, Solid Tumor, Metastatic Microsatellite-stable Colorectal Cancer
|
Phase 1/2 | Active, closed | Rottapharm Biotech | Italy |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
| Lead sponsor | Trials |
|---|---|
| Rottapharm Biotech | 1 |
| Gruppo Oncologico del Nord-Ovest | 1 |
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in Italy | 2 | 1 |
A trial with sites in more than one country appears in each of those registers.
2 current trials in our Italy register name Vorbipiprant (also registered as CR6086) as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.
Yes. 1 of the 2 trials is recruiting: 1 with sites in Italy. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Rottapharm Biotech (1) and Gruppo Oncologico del Nord-Ovest (1). The number in brackets is how many trials each organisation leads.
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Vorbipiprant works or whether it is effective, and it is not medical advice.
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Vorbipiprant works or whether it is effective. Each trial links to its own record so you can check it yourself.
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Vorbipiprant (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.