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Trackers› Clinical trials› Milan
Clinical trial register · Italy

Clinical Trials in Milan, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Italy and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 6779 matching records held by the registry are in this view. Synced 10 Nov 2026, 03:19 UTC
6779
Studies in scope
all four open statuses
4070
Recruiting now
open to new participants
1013
Lead sponsors
across recruiting studies
Top sites
Milan 2847 Bologna 1281 Roma 1263 Naples 980 Rome 966
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
IRCCS San Raffaele156 AstraZeneca140 Merck Sharp & Dohme LLC98 Hoffmann-La Roche77 Novartis Pharmaceuticals74 European Institute of Oncology73 Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico62 Janssen Research & Development, LLC62 Eli Lilly and Company52 AbbVie50 Bristol-Myers Squibb49 I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio45 Sanofi44 Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta39 Fondazione IRCCS Istituto Nazionale dei Tumori, Milano39 GlaxoSmithKline36 Istituto Auxologico Italiano36 Amgen31 Fondazione Don Carlo Gnocchi ETS30 Università Vita-Salute San Raffaele29 Pfizer28 Niguarda Hospital27 Incyte Corporation27 University of Milan23 Daiichi Sankyo22 Show all 720
Site location
Milan2847 Bologna1281 Roma1263 Naples980 Rome966 Florence788 Pavia571 Brescia523 Padova503 Genova491 Rozzano472 Bari451 Pisa399 Bergamo378 Meldola355 Catania340 Ancona298 Verona282 Monza281 Palermo276 Torino275 Modena259 Aviano201 Messina168 Alessandria164 Show all 491
All 491 locations
Target enrolment
to

Trials with a site in Milan

2847 of 6779 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Italy
Start
Not yet open
Correlation and Rapid Analysis of Neurological Injury Using Markers
NCT06834659Traumatic Brain Injury (TBI) Patients
Università Vita-Salute San Raffaele
Observational
200
Milan
2027-06
Not yet open
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Phase 3
92
Rome, Milan, Pisa
2027-02-03
Not yet open
Boehringer Ingelheim
Phase 3
1,500
Bologna, Catania, Florence, Genova, Messina, Milan, Monza (MB), Naples
2027-01-11
Not yet open
University of Milan
Observational
30
Milan
2026-12-01
Not yet open
UNICANCER
Not applicable
2,000
Milan
2026-12-01
Not yet open
Effect of add-on Doxofylline on Lung Function in Stable COPD
NCT04238221Chronic Obstructive Pulmonary Disease
University of Milan
Phase 4
78
Milan
2026-12-01
Not yet open
New Biomarkers for Organ Viability Assessment During Hypothermic Machine Perfusion in Liver Transplantation: the Role of Extemporaneous Histological Examination.
NCT07674394Liver Transplantation (LT), Early Allograft Dysfunction, Primary Non-function, Ischemia-Reperfusion Injury
The Mediterranean Institute for Transplantation and Advanced Specialized Therapies
Not applicable
150
Milan, Palermo, Roma
2026-12
Not yet open
IRCCS San Raffaele
Not applicable
200
Milan
2026-12
Not yet open
Eli Lilly and Company
Phase 3
3,000
Arezzo, Baggiovara, Bologna, Ceccano, Chieti, Florence, Milan, Naples
2026-12
Not yet open
Institut National de la Santé Et de la Recherche Médicale, France
Not applicable
120
Milan, Padova
2026-12
Not yet open
Chiesi Farmaceutici S.p.A.
Phase 3
700
Brescia, Brindisi, Genoa, Messina, Milan, Naples, Parma, Pisa
2026-11-16
Not yet open
Twenty-five Years of Advanced RadioTherapy at San Raffaele Hospital
NCT07894900Malignant Tumor, Benign Neoplasm, Parkinson Disease, Trigeminal Neuralgia
IRCCS San Raffaele
Observational
10,000
Milan
2026-11-15
Not yet open
Gut Microbiome in Patients With Lung and Melanoma Cancer and Intestinal Microbiota in Gynecologic Cancers
NCT07815873Non Small Cell Lung Cancer, Melanoma (Skin Cancer), Endometrial Cancer, Cervical Cancer
DrugSample collection
European Institute of Oncology
Not applicable
360
Milan
2026-11-11
Not yet open
Novo Nordisk A/S
Phase 3
1,408
Bari, Catanzaro, Ferrara, Rome, Brescia, Milan, Pozzilli (IS), Palermo
2026-11-11
Recruiting
University of Milan
Not applicable
46
Milan
2026-11-10
Not yet open
Fondazione Don Carlo Gnocchi ETS
Not applicable
30
Milan
2026-11-03
Recruiting
Centro Cardiologico Monzino
Not applicable
250
Cosenza, Milan, Verona, Brescia
2026-11-01
Not yet open
Ciceri Fabio
Observational
70
Milan
2026-11-01
Not yet open
IRCCS San Raffaele
Observational
376
Milan
2026-11
Not yet open
European Organisation for Research and Treatment of Cancer - EORTC
Phase 2
158
Brescia, Milan, Roma, Udine
2026-11
Not yet open
BV-CHP Real-life and Biological Evidences in Patients With sALCL
NCT07467317Anaplastic Large Cell Lymphoma
Fondazione Italiana Linfomi - ETS
Observational
100
Avellino, Aviano, Bari, Bergamo, Bologna, Candiolo, Legnano, Milan
2026-11
Not yet open
Innovative 3D Preclinical Models for Mature B-cell Malignancies to Advance Personalized Immuno and Combination Therapies
NCT07759661Chronic Lymphocytic Leukemia (CLL), Splenic Marginal Zone Lymphoma, Hairy Cell Leukemia (HCL)
IRCCS San Raffaele
Observational
64
Milan
2026-11
Not yet open
Endoscopic Management of Biliopancreatic Disease in the Lombardy Pancreas Units
NCT07418164Pancreatic Cancer, Biliopancreatic Diseases, Periampullary Neoplasms
IRCCS San Raffaele
Observational
2,500
Bergamo, Brescia, Cremona, Legnano, Mantua, Milan, Monza, Pavia
2026-10-31
Not yet open
EUS-Based Artificial Intelligence to Predict Outcomes in Pancreatic Cancer
NCT07803770Pancreatic Neoplasms, Pancreatic Ductal Adenocarcinoma (PDAC), Artificial Intelligence (AI), Endoscopic Ultrasound (EUS)
IRCCS San Raffaele
Observational
700
Milan
2026-10-31
Recruiting
Niguarda Hospital
Not applicable
60
Milan
2026-10-30
Recruiting
Novo Nordisk A/S
Phase 3
84
Naples, Florence, Milan, Padova
2026-10-16
Not yet open
Cefepime/Enmetazobactam for Bacteremic Complicated Urinary Tract Infections
NCT07725848Complicated Urinary Tract Infections, Antibiotic Resistance
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
200
Bologna, Catania, Milan
2026-10-15
Not yet open
Medtronic MiniMed, Inc.
Not applicable
230
Bologna, Milan, Naples, Roma
2026-10-15
Recruiting
A Study of DS-3939a in Participants With Solid Tumors
NCT07739966Solid Tumor, Locally Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer
DrugsDS-1103a·DS-3939a·Pemetrexed·Carboplatin
Daiichi Sankyo
Phase 1/2
400
Milan, Orbassano, Pavia, Perugia, Ravenna, Rome
2026-10-13
Not yet open
Dermatological Effects and Quality of Life in Oncology Patients
NCT07869186Breast Cancer, Ovarian Cancer, NSCLC (Non-small Cell Lung Cancer), Melanoma (Skin Cancer)
European Institute of Oncology
Not applicable
300
Milan
2026-10-12
Active, closed
Epigenetic Changes in Long COVID Patients
NCT07757620Long COVID-19 Syndrome, Long COVID Symptoms
Istituti Clinici Scientifici Maugeri SpA
Observational
1,000
Cusano Milanino, Milan, Pavia
2026-10-12
Recruiting
Fight Osteosarcoma Through European Research Evolving Study Platform From Diagnosis to Relapse
NCT07871864Osteosarcoma, Pediatric Osteosarcoma, Osteosarcoma in Children, Osteosarcoma in Adolescents and Young Adults
Gustave Roussy, Cancer Campus, Grand Paris
Phase 3
530
Bologna, Genova, Milan, Padova, Pisa, Roma, Torino
2026-10-07
Recruiting
Hoffmann-La Roche
Phase 3
400
Rome, Bergamo, Milan, Florence, Perugia, Peschiera Del Garda (VR)
2026-10-06
Recruiting
Ad scientiam
Not applicable
100
Milan, Pavia, Pisa, Roma
2026-10-06
Recruiting
IRCCS San Raffaele
Not applicable
40
Milan
2026-10-05
Recruiting
Efficacy and Safety of Two Hair Supplements in Men With Androgenic Alopecia
NCT07806474Androgenic Alopecia, Healthy Adult Male
Activ'inside
Not applicable
99
Rende, Ferrara, Garbagnate Milanese, Milan, Biella, San Martino Siccomario
2026-10-05
Active, closed
Real-World Effectiveness of Conservative Treatment in Idiopathic Scoliosis
NCT07873554Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis (AIS), Juvenile Idiopathic Scoliosis
Istituto Scientifico Italiano Colonna Vertebrale
Observational
30,000
Milan
2026-10-02
Not yet open
Digital Patient Engagement in Technology-Supported Neurorehabilitation
NCT07794072Stroke, Parkinson Disease (PD), Motor Neuron Disease, Spinal Cord Injury
Catholic University, Italy
Observational
129
Milan, Montescano, Pavia
2026-10-01
Not yet open
PhoenixLAB srls
Not applicable
30
Milan
2026-10-01
Recruiting
Niguarda Hospital
Not applicable
12
Milan
2026-10-01
Not yet open
IRCCS San Raffaele
Not applicable
192
Milan, Verona
2026-10-01
Recruiting
Faron Pharmaceuticals Ltd
Phase 2
90
Alessandria, Bologna, Candiolo, Milan
2026-10
Not yet open
AYUrvedic Foot Massage for Symtoms of Taxane-induced Peripheral nEuroPathy
NCT07884071Chemotherapy-induced Peripheral Neuropathy (CIPN)
European Institute of Oncology
Not applicable
20
Milan
2026-10
Recruiting
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Not applicable
20
Milan
2026-10
Recruiting
A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency.
NCT07559175Exocrine Pancreatic Insufficiency (EPI), Cystic Fibrosis (CF), Pancreatic Enzyme Abnormality, Pancreatic Diseases
DrugZenpep
Aimmune Nestlé Health Science US R&D, LLC
Phase 2
66
Catania, Rozzano, Messina, Florence, Milan, Roma
2026-10
Not yet open
TOLerogenic Potential of Hematopoietic Stem and Progenitor Cells and Inflammatory Bowel Disease
NCT07740499Inflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis)
IRCCS San Raffaele
Observational
80
Milan, Rome
2026-10
Not yet open
Fondazione EMN Italy Onlus
Observational
92
Bari, Bologna, Brescia, Castelfranco Veneto, Como, Milan, Novara, Pavia
2026-10
Not yet open
Assembly Biosciences
Phase 2
80
Milan, Naples
2026-10
Not yet open
Colchicine Effect on Amyotrophic Lateral Sclerosis Patients
NCT07813858Amyotrophic Lateral Sclerosis
DrugColchicine
Azienda Ospedaliero-Universitaria di Modena
Phase 2
87
Milan, Modena, Naples, Novara, Pavia
2026-10
Recruiting
University Hospital Tuebingen
Phase 2
120
Brescia, Milan, Pavia
2026-10
Not yet open
PULSTA TPV Observational Study
NCT07747207Heart Disease
Taewoong Medical Co., Ltd.
Observational
200
Milan
2026-10
Not yet open
Daiichi Sankyo
Phase 3
103
Milan, Naples, Negrar
2026-09-30
Not yet open
Scienceforbrain, UAB
Not applicable
304
Milan
2026-09-30
Recruiting
Solstice Oncology, Inc.
Phase 2
100
Milan, Naples, Pisa
2026-09-30
Recruiting
Abbott Medical Devices
Not applicable
50
Mercogliano, Milan
2026-09-29
Recruiting
Corbus Pharmaceuticals Inc.
Phase 3
260
Ancona, Milan, Modena, Pisa, Prato, Rozzano, Verona
2026-09-29
Recruiting
AstraZeneca
Phase 3
750
Bologna, Milan, Rome, Rozzano, Torino
2026-09-24
Recruiting
Torvutatug Samrotecan With or Without Bevacizumab as Maintenance Treatment of Platinum-sensitive Relapsed Epithelial Ovarian Cancer
NCT07816666Platinum-sensitive Relapsed Epithelial Ovarian Cancer, Platinum-sensitive Relapsed Fallopian Tube Cancer, Platinum-sensitive Relapsed Primary Peritoneal Cancer
DrugsTorvutatug samrotecan·Bevacizumab
AstraZeneca
Phase 3
600
Milan, Monza, Naples, Rome, Torino, Treviso
2026-09-24
Recruiting
Morrow Eyewear
Not applicable
50
Milan
2026-09-24
Recruiting
European Institute of Oncology
Observational
35
Milan
2026-09-22
Recruiting
How to Prevent Post-surgery Infections
NCT07848269ASA III, Elective Prosthetic Surgery, Patient Bedridden After Surgery
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Not applicable
164
Milan
2026-09-20
Recruiting
Daiichi Sankyo
Phase 1/2
220
Aviano, Meldola, Milan, Monza, Padova, Pisa
2026-09-17
Recruiting
AstraZeneca
Phase 3
950
Florence, Genova, Milan, Parma
2026-09-16
Recruiting
Effective Communication in Perinatal Care
NCT07919145Pregnancy, Vbac
IRCCS San Raffaele
Observational
50
Milan
2026-09-16
Recruiting
Transcranial Alternating Current Stimulation (tACS) Combined With Cognitive Training in Alzheimer's Disease
NCT07839650Transcranial Alternating Current Stimulation, Alzheimer Disease (AD), Alzheimer Dementia (AD), Cognitive Rehabilitation
IRCCS Centro San Giovanni di Dio Fatebenefratelli
Not applicable
30
Brescia, Milan
2026-09-16
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
90
Ancona, Florence, Genova, Messina, Milan, Roma, Rome, Verona
2026-09-15
Not yet open
Thymic Disease, Autoimmunity, and Neuromuscular Junction Integrity in Myasthenia Gravis
NCT07571525Myasthenia Gravis (MG), Myasthenia Gravis Associated With Thymoma, Thymoma
IRCCS San Raffaele
Observational
40
Milan
2026-09-15
Recruiting
CSL Behring
Phase 3
63
Rome, Brescia, Varese, Candiolo, Catania, Florence, Milan
2026-09-15
Recruiting
Italian Trigeminal Autonomic Cephalalgias Assessment Study
NCT07812740Trigeminal Autonomic Cephalalgias, Cluster Headache, Paroxysmal Hemicrania, SUNCT
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Observational
800
Milan
2026-09-15
Recruiting
Stereotactic Body RadioTherapy With Continuous Tracking for Primary and Secondary Renal Cancer
NCT07285538Renal Cancer, Renal Secondary Cancer, Stereotactic Body Radiotherapy
IRCCS San Raffaele
Not applicable
60
Milan
2026-09-14
Active, closed
Massimo Falconi
Observational
30
Milan
2026-09-12
Recruiting
Vividion Therapeutics, Inc.
Phase 2
140
Naples, Rome, Milan, Rozzano
2026-09-11
Recruiting
Takeda
Phase 3
324
Bologna, Cona, Meldola, Rome, Milan, Ancona, Catania, Florence
2026-09-10
Recruiting
Bristol-Myers Squibb
Phase 2
160
Bergamo, Misterbianco, Bari, Milan, Ravenna, Rozzano (MI)
2026-09-10
Recruiting
Janssen Research & Development, LLC
Phase 3
1,000
Bologna, Cuneo, Milan, Palermo
2026-09-09
Recruiting
Bristol-Myers Squibb
Phase 3
850
Bergamo, Meldola, Candiolo, Brescia, Milan, Pavia, Verona
2026-09-08
Recruiting
Incyte Corporation
Phase 3
426
Bari, Bergamo, Bologna, Catania, Florence, Genova, Meldola, Milan
2026-09-08
Recruiting
IRCCS San Raffaele
Not applicable
630
Milan
2026-09-01
Recruiting
Bayer
Phase 2
360
Acquaviva delle Fonti, Rome, Milan, Torrette
2026-09-01
Recruiting
Disparities in Mental Health Screening and Support
NCT07691281Mental Health, Cancer
European Institute of Oncology
Observational
2,000
Milan
2026-09-01
Recruiting
AstraZeneca
Phase 3
2,800
Bari, Bologna, Cosenza, Cremona, Genoa, Milan, Modena, Naples
2026-09-01
Not yet open
Pierachille Santus, MD, PhD
Not applicable
30
Milan
2026-09-01
Not yet open
Alfonso Magliacano
Observational
79
Sant'Angelo dei Lombardi, Florence, Milan
2026-09-01
Not yet open
Università Vita-Salute San Raffaele
Not applicable
20
Milan
2026-09-01
Recruiting
AusperBio Therapeutics Inc.
Phase 2
70
Milan
2026-09-01
Recruiting
A Phase 3 Study to Evaluate the Safety and Efficacy of AOC 1044 (Also Referred to as Delpacibart Zotadirsen) in Participants With DMD With Gene Mutations Amenable to Exon 44 Skipping
NCT07587242Muscular Dystrophies, Muscular Dystrophies (Duchenne, Becker, Myotonic Dystrophy), Muscular Disorders, Atrophic, Muscular Disease
DrugAOC 1044
Avidity Biosciences, Inc.
Phase 3
70
Genova, Milan, Roma
2026-09-01
Active, closed
Centro Cardiologico Monzino
Not applicable
300
Milan
2026-09-01
Not yet open
IRCCS San Raffaele
Observational
142
Roma, Milan
2026-09-01
Not yet open
University of Pavia
Observational
38
Milan, Pavia
2026-09-01
Not yet open
Targeting GLUT1 to Control Autoimmunity in Type 1 Diabetes
NCT07695727Type 1 Diabetes, Autoimmunity
IRCCS San Raffaele
Observational
84
Milan
2026-09
Not yet open
IRCCS San Raffaele
Not applicable
55
Milan
2026-09
Not yet open
Neurocognitive Integrity After Proton Therapy for Brain Tumor
NCT07836478Central Nervous System Tumour
European Institute of Oncology
Observational
60
Milan
2026-09
Not yet open
International Extranodal Lymphoma Study Group (IELSG)
Observational
400
Milan
2026-09
Not yet open
Prospective Perioperative Clinical Registry for Women Undergoing Benign Gynecological Surgery
NCT07772076Benign Gynecological Disease, Uterine Fibroids, Endometriosis, Adenomyosis
IRCCS San Raffaele
Observational
6,000
Milan
2026-09
Not yet open
Italian Validation of the dNA Scale and Its Correlation With Neurocognitive Variables
NCT07533084Active Aging Individuals Aged 65 and Over, Aging, Mild Cognitive Impairment (MCI), Dementia
Neuromed IRCCS
Observational
265
Brescia, Genova, Pozzilli, Milan, Pavia, Roma, Venezia
2026-09
Not yet open
PhiCube for Bilateral Upper Limb Neuromotor and Cognitive Rehabilitation in Adults
NCT07865260Stroke, Parkinson Disease, Amyotrophic Lateral Sclerosis, Spinal Cord Injuries
Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato
Not applicable
80
Bari, Milan, Montescano, Telese Terme
2026-09
Not yet open
Neurocognitive Assessment in Long-Term Survivors of Lymphoma
NCT07652476Classic Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma (DLBCL), Primary Mediastinal B Cell Lymphoma
Fondazione Italiana Linfomi - ETS
Observational
100
Ancona, Aviano, Bari, Legnano, Milan, Palermo
2026-09
Recruiting
AstraZeneca
Phase 3
1,072
Brescia, Catania, Cona, Florence, Milan, Pavia, Roma
2026-08-31
Not yet open
Azienda USL Reggio Emilia - IRCCS
Observational
210
Bari, Bologna, Ferrara, Meldola, Milan, Modena, Naples, Reggio Emilia
2026-08-30
Recruiting
Kardigan, Inc.
Phase 3
332
Bari, Florence, Milan, Padova, Pavia, Roma, Rozzano, Trieste
2026-08-26
Recruiting
MELanoma Brain Metastasis Treated With CYberknife
NCT07691255Melanoma (Skin Cancer)
European Institute of Oncology
Observational
50
Milan
2026-08-25
Recruiting
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
NCT07761117Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
DrugElecoglipron
AstraZeneca
Phase 3
6,950
Ancona, Bergamo, Brescia, Milan, Pavia, Perugia, Riccione, Salerno
2026-08-24
Recruiting
Novo Nordisk A/S
Phase 3
1,778
Chieti, Catanzaro, Naples, Ravenna, Chiavari, Milan, Roma, Lucca
2026-08-24
Recruiting
AstraZeneca
Phase 3
2,500
Bologna, Milan, Palermo, Pisa, Roma, Rozzano, Sesto San Giovanni, Torino
2026-08-19
Active, closed
Pivotal Study of N-acetyl-L-leucine for CACNA1A
NCT07221292CACNA1A, Spinocerebellar Ataxia Type 6, Episodic Ataxia Type 2, Familial Hemiplegic Migraine-1
DrugN-Acetyl-L-Leucine
IntraBio Inc
Phase 3
60
Milan, Rome
2026-08-17
Recruiting
Genespire Srl
Observational
30
Milan, Roma
2026-08-13
Recruiting
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Not applicable
142
Milan
2026-08-06
Recruiting
Real-World Effectiveness and Safety of Pegcetacoplan in Patients With C3G or IC-MPG: A Multi-Country Study
NCT07746895C3 Glomerulopathy (C3G), Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN)
DrugPegcetacoplan
Swedish Orphan Biovitrum
Phase 4
150
Bari, Bologna, Foggia, Messina, Milan, Roma, Udine
2026-08-05
Not yet open
Using Artificial Intelligence to Detect Early Signs of Alzheimer's Disease in People With Memory Concerns
NCT07652931Subjective Cognitive Decline, Alzheimer Disease, Mild Cognitive Impairment, Cognitive Decline
IRCCS San Raffaele
Not applicable
300
Milan
2026-08-01
Recruiting
Preclinical Assessment of an Engineered HMGB1 Protein as a Novel Companion Therapy for Muscular Dystrophies
NCT07745218LAMA2-MD (Merosin Deficient Congenital Muscular Dystrophy, MDC1A)
IRCCS San Raffaele
Observational
25
Milan
2026-08-01
Recruiting
VectivBio AG
Phase 3
124
Pavia, Padova, Bologna, Florence, Milan, Torino
2026-08
Not yet open
Entrada Therapeutics, Inc.
Phase 2
80
Milan, Roma, Rome
2026-08
Recruiting
Guerbet
Phase 3
315
Bergamo, Cagliari, Chieti, Milan, Roma, Treviso
2026-07-28
Recruiting
Boehringer Ingelheim
Phase 3
448
Ancona, Bari, Florence, Milan, Modena, Naples, Roma
2026-07-27
Recruiting
GlaxoSmithKline
Phase 3
800
Milan, Palermo, Roma
2026-07-27
Recruiting
Bristol-Myers Squibb
Phase 2
254
Siena, Bergamo, Milan, Naples, Perugia
2026-07-27
Recruiting
Versius Clinical Study in Robot Assisted Inguinal Hernia Repair Surgery
NCT07316517Robotic Assisted Inguinal Hernia Repair
CMR Surgical Ltd
Not applicable
30
Milan
2026-07-22
Active, closed
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
40
Milan
2026-07-21
Recruiting
UCB BIOSCIENCES, Inc.
Phase 3
200
Genova, Milan, Naples, Pisa, Troina
2026-07-14
Recruiting
Molnlycke Health Care AB
Not applicable
40
Milan
2026-07-13
Recruiting
Boehringer Ingelheim
Phase 3
390
Florence, Milan, Naples, Palermo, Roma, Verona
2026-07-10
Recruiting
Eli Lilly and Company
Phase 3
170
Ancona, Florence, Genova, Messina, Milan, Naples, Verona
2026-07-08
Recruiting
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
1,683
Milan
2026-07-08
Recruiting
Fondazione Telethon
Phase 2
9
Rome, Milan
2026-07-06
Recruiting
AstraZeneca
Phase 3
1,200
Bari, Bologna, Chieti, Milan, Modena, Naples, Roma
2026-07-06
Recruiting
Abbott Medical Devices
Observational
1,000
Milan
2026-07-02
Active, closed
IRCCS San Raffaele
Observational
30
Milan
2026-07-01
Recruiting
Prilenia
Phase 3
400
Bologna, Milan, Naples, Padova, Roma, San Giovanni Rotondo
2026-07-01
Not yet open
Air-in-Line Alarms During Antineoplastic Drug Infusion
NCT07718711Infusion Safety, Medication Safety, Antineoplastic Drug Administration, Air-in-Line Alarm
Associazione Italiana Infermieri di Area Oncologica
Observational
40
Parma, Rome, Lodi, Milan
2026-07-01
Recruiting
Appropriateness of Hemostatic Agent Use in Cardiovascular Surgery (HAEMOVAX)
NCT07699016Hemostasis, Perioperative Bleeding, Cardiovascular Surgery, Cardiac Surgery
University of Milan
Observational
15
Milan
2026-07-01
Not yet open
Clinical Predictors of Visual Outcome in Patients Affected With Ocular Surface Diseases
NCT07694817Neurotrophic Keratopathy, Exposure Keratopathy, Limbal Stem Cell Deficiency (LSCD), Cornea Abnormality
IRCCS San Raffaele
Observational
1,000
Milan
2026-07
Not yet open
Effect of EGCG, Folic Acid, Vitamin B12 and Hyaluronic Acid on HPV DNA Integration
NCT07697196HPV Infection, HPV Integration, HPV Disease, HPV Genital Infection
IRCCS San Raffaele
Not applicable
42
Milan
2026-07
Not yet open
IRCCS San Raffaele
Observational
50,000
Lecco, Milan, Novara, Varese
2026-07
Not yet open
University Medical Center Groningen
Not applicable
292
Florence, Lavagna, Milan, Nola, Reggio Emilia, Roma, Tricase
2026-07
Recruiting
Istituto Clinico Humanitas
Observational
40
Milan
2026-06-30
Recruiting
[68Ga]BED003 PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications
NCT07702292Colorectal Cancer, Epithelial Ovarian Cancer, Gastric Cancer (GC), Pancreatic Ductal Adenocarcinoma (PDAC)
Blue Earth Diagnostics
Phase 2
71
Bergamo, Monza, Roma, Milan
2026-06-30
Active, closed
Istituto Auxologico Italiano
Observational
790
Milan
2026-06-30
Recruiting
Promoting Walking Among Older Adults Through Affective Communication and Step-Monitoring
NCT07570303Walking, Older Adults (65 Years and Older), Messaging, Mobile Applications
Catholic University, Italy
Not applicable
1,000
Milan
2026-06-29
Recruiting
AstraZeneca
Phase 3
4,500
Bologna, Catania, Chieti, Florence, Latina, Milan, Pisa, Ravenna
2026-06-29
Recruiting
AstraZeneca
Phase 3
750
Bologna, Milan, Rome, Rozzano, Torino
2026-06-26
Active, closed
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
61
Milan
2026-06-22
Recruiting
Fondazione Telethon
Phase 1/2
8
Milan
2026-06-20
Recruiting
GlaxoSmithKline
Phase 1/2
49
Rozzano, Alessandria, Milan
2026-06-19
Recruiting
OPTION-EMEA Clinical Trial
NCT07349121Atrial Fibrillation (AF), Stroke Prevention in Patients With Atrial Fibrillation, Left Atrial Appendage Closure, Pulsed Field Ablation
Boston Scientific Corporation
Not applicable
500
Milan, San Donato Milanese
2026-06-18
Recruiting
Merck Sharp & Dohme LLC
Phase 3
310
Meldola, Rome, Milan
2026-06-18
Recruiting
Predictors of Major Adverse Limb Events After Endovascular Iliac Stenting: a Real-world Cohort Study
NCT07672249Peripheral Arterial Disease, Aortoiliac Occlusive Disease, Chronic Limb-Threatening Ischemia, Intermittent Claudication
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
98
Milan
2026-06-16
Recruiting
AstraZeneca
Phase 3
150
Aviano, Bergamo, Genova, Milan, Naples
2026-06-15
Not yet open
Catholic University of the Sacred Heart
Not applicable
224
Milan
2026-06-15
Recruiting
Fondazione Luigi Villa
Observational
20
Florence, Milan
2026-06-14
Recruiting
Pharming Technologies B.V.
Phase 2
140
Messina, Milan, Pisa
2026-06-12
Active, closed
AstraZeneca
Phase 2
326
Bologna, Florence, Milan, Padova, Pavia, Pisa, Torino, Torrette - Ancona
2026-06-11
Recruiting
Panuri Performance Study
NCT07587866Pancreatic Ductal Adenocarcinoma (PDAC)
Urteste S.A
Observational
1,100
Forlì, Milan, Pavia, Pisa, Roma, Rozzano
2026-06-10
Recruiting
18F FES-PET/MRI for Tailoring Treatment of Luminal A and Lobular Breast Cancer
NCT05982496Breast Cancer Female, Lobular Breast Carcinoma, PET/MRI, Axillary Lymphadenopathy
Università Vita-Salute San Raffaele
Phase 2
119
Milan
2026-06-09
Active, closed
Rollover Study for Participants Who Have Been Treated With and Are Continuing to Benefit From Opnurasib as a Single Agent or in Combination With Other Study Treatments
NCT07468071Locally Advanced or Metastatic KRAS G12C-mutated Non-small Cell Lung Cancer, Advanced Solid Tumors Harboring the KRAS G12C Mutation
DrugsTNO155·Opnurasib·Trametinib·Cetuximab
Novartis Pharmaceuticals
Phase 1/2
25
Milan, Roma
2026-06-08
Active, closed
Open-Label Extension Study of BBP-418 (Ribitol) for LGMD2I/R9
NCT07678775Limb-Girdle Muscular Dystrophy Type 2I (LGMD2I)
DrugRibitol
ML Bio Solutions, Inc.
Phase 3
107
Milan
2026-06-05
Recruiting
Fondazione Italiana Linfomi - ETS
Phase 2
41
Alessandria, Bologna, Brescia, Florence, Genova, Milan, Palermo, Pescara
2026-06-05
Recruiting
Alianza multidisciplinar para la investigación de los tumores genitourinarios -GUARD
Phase 3
320
Catania, Foggia, Milan, Roma
2026-06-05
Recruiting
AstraZeneca
Phase 2
80
Meldola, Milan, Padua, Ravenna, Rome, Torino
2026-06-04
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
40
Milan
2026-06-04
Recruiting
AstraZeneca
Phase 1/2
152
Bergamo, Meldola, Milan, Roma
2026-06-03
Recruiting
A Liquid Biopsy for Pancreatic Cancer Early-detection and Disease Monitoring
NCT07700992Familial Pancreatic Cancer, Familial Pancreatic Carcinoma, Hereditary Pancreatic Cancer, Hereditary Pancreatitis
Università Vita-Salute San Raffaele
Observational
600
Milan
2026-06-03
Recruiting
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Not applicable
192
Milan
2026-06-03
Recruiting
A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy
NCT07498426Progressive Supranuclear Palsy Richardson Syndrome (PSP-RS)
Novartis Pharmaceuticals
Phase 3
300
Genova, Milan, Padova, Roma, Salerno
2026-06-03
Recruiting
Dompé Farmaceutici S.p.A
Phase 3
150
Perugia, S. Andrea Delle Fratte, Florence, Milan, Pavia, Roma
2026-06-02
Not yet open
Periodontal Disease in Patients With Lynch Syndrome
NCT07600710Lynch Syndrome, Periodontal Disease
Rotundo Roberto
Observational
25
Milan
2026-06-01
Not yet open
Safety of Bronchoscopy in Patients With Interstitial Lung Disease
NCT07627594Interstitial Lung Disease (ILD), Bronchoscopy, Bronchoalveolar Lavage (BAL), Acute Exacerbation
University of Milan
Observational
427
Milan, Bologna, Genova, Legnano, Modena, Monza, Naples, Siena
2026-06-01
Active, closed
Centro Cardiologico Monzino
Observational
2,000
Milan
2026-06-01
Active, closed
Centro Cardiologico Monzino
Observational
1,046
Milan
2026-06-01
Recruiting
Niguarda Hospital
Not applicable
70
Milan
2026-06-01
Not yet open
Niguarda Hospital
Not applicable
72
Milan
2026-06-01
Recruiting
Bayer
Phase 3
117
Rome, Genoa, Turin, Padova, Bergamo, Bologna, Milan, Naples
2026-06-01
Not yet open
The MICROSCOPE Project
NCT07153224Early Career Surgeons, Mental Wellbeing, Patients Outcomes, Mentorship
Niguarda Hospital
Observational
340
Milan
2026-06-01
Not yet open
University Hospital, Antwerp
Not applicable
266
Milan
2026-06-01
Not yet open
Gruppo Oncologico Italiano di Ricerca Clinica
Phase 2
144
Bari, Bologna, Meldola, Foggia, Florence, Genova, Province of Macerata, Milan
2026-06
Not yet open
Evaluation of the Impact of Virtual Park on Training Motivation in Adult Patients
NCT07616050Post-stroke, Parkinson Disease, Amyotrophic Lateral Sclerosis, Mild Cognitive Impairment (MCI)
Marta Mondellini
Not applicable
70
Bari, Telese Terme, Costa Masnaga, Milan, Montescano, Pavia, Pisa
2026-06
Recruiting
Janssen Research & Development, LLC
Phase 3
700
Bari, Bologna, Bolzano, Milan, Novara, Palermo, Pescara, Rimini
2026-05-31
Not yet open
Isoniazid-Related Hepatotoxicity in Clinical Practice: Incidence and Predictors
NCT07472348Tuberculosis Infection, Tuberculosis Infection, Latent
ASST Fatebenefratelli Sacco
Observational
220
Milan
2026-05-30
Recruiting
BIO|STREAM.CSP CLS
NCT07608822Sinus Node Disease, Atrioventricular Block
Biotronik SE & Co. KG
Observational
150
Brindisi, Milan, Novara, Piove di Sacco, Roma, Taranto
2026-05-29
By invitation
Novo Nordisk A/S
Observational
214
Pescara, San Giovanni in Fiore (CS), Marano Di Napoli (NA), Rome, Milan, Cuneo, Catania, Bolzano
2026-05-28
Recruiting
Pfizer
Phase 2
24
Bergamo, Milan, Florence
2026-05-28
Recruiting
Augmented Reality in Surgery
NCT07636278Anterior Cruciate Ligament (ACL) Tear
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
100
Milan
2026-05-26
Recruiting
BIO|STREAM.CSP Study
NCT07393009Cardiac Pacing, Cardiac Pacemaker, Implantable Cardioverter Defibrillator, Cardiac Resynchronization Therapy Devices
Biotronik SE & Co. KG
Observational
1,000
Bergamo, Brindisi, Milan, Novara, Piove di Sacco, Roma, Taranto
2026-05-25
Recruiting
Novartis Pharmaceuticals
Phase 1
208
Milan
2026-05-25
Recruiting
Janssen Research & Development, LLC
Phase 3
644
Milan, Negrar, Romagnano, Rozzano
2026-05-23
Recruiting
Endoscopic Video-Assisted Nipple-Sparing Mastectomy
NCT07579117Endoscopic Video-assisted Nipple-sparing Mastectomy, Breast Surgery, Breast Cancer
European Institute of Oncology
Not applicable
10
Milan
2026-05-23
Recruiting
BeOne Medicines
Phase 3
1,056
Bergamo, Milan, Monza, Roma
2026-05-22
Recruiting
Janssen Research & Development, LLC
Phase 3
460
Milan, Negrar, Romagnano, Rozzano
2026-05-22
Recruiting
Novo Nordisk A/S
Phase 3
2,500
Bologna, Genoa, Brescia, Milan, Perugia, Messina, Ancorna, Pisa
2026-05-21
Recruiting
Takeda
Phase 3
300
Florence, Rozzano, Pavia, Roma, Candiolo, Bologna, Milan, Naples
2026-05-21
Recruiting
Novartis Pharmaceuticals
Phase 1
24
Milan, Candiolo
2026-05-19
Recruiting
Safety and Efficacy of Iron Prophylaxis With on Iron Homeostasis in Healthy Pregnant Women
NCT07884617Iron Deficiency Anemia in Pregnancy, Iron Deficiency in Pregnancy
IBSA Farmaceutici Italia Srl
Not applicable
162
Milan
2026-05-18
Active, closed
Evaluation of Safety of Complex Pedicle Screw Trajectories Using Patient-Specific Guides (MySpine, Medacta)
NCT07790068Scoliosis Idiopathic, Scoliosis Idiopathic Adolescent, Scoliosis Associated With Other Conditions, Scoliosis Idiopathic Adolescent Treatment
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
130
Milan
2026-05-15
Recruiting
Hoffmann-La Roche
Phase 3
138
Naples, Milan, Rozzano, Florence
2026-05-15
Recruiting
University of Milan
Not applicable
148
Milan, Catania
2026-05-15
Recruiting
Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer
NCT07392892Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma, Metastatic Gastric Cancer, Gastroesophageal Junction Cancer, Esophageal Adenocarcinoma
DrugsPF-08634404·Nivolumab
Pfizer
Phase 2/3
840
Milan
2026-05-14
Recruiting
Ipsen
Phase 3
350
Genova, Milan, Modena, Monza, Novara, Padova, Roma, Rozzano
2026-05-14
Recruiting
Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1
NCT07486934Myotonic Dystrophy Type 1 (DM1), DM1, Myotonic Dystrophy, Steinert Disease
DrugZeleciment basivarsen
Dyne Therapeutics
Phase 3
150
Gussago, Milan, Roma
2026-05-14
Recruiting
Eli Lilly and Company
Phase 2
600
Genova, Milan, Misterbianco, Prato, Roma
2026-05-13
By invitation
IRCCS San Raffaele
Not applicable
75
Milan
2026-05-13
Recruiting
Multicenter Study for External Validation of the TB-NET Score
NCT07903532Tumor Burden, Neuroendocrine (NE) Tumors
Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Observational
400
Milan
2026-05-12
Recruiting
European Institute of Oncology
Phase 2
26
Milan
2026-05-11
Recruiting
Incyte Corporation
Phase 1
218
Bologna, Milan, Roma, Udine
2026-05-11
Active, closed
Novartis Pharmaceuticals
Phase 3
5,700
Ancona, Bergamo, Bologna, Brescia, Cona, Florence, Pozzilli, Milan
2026-05-11
Recruiting
Showers and Stress
NCT07611422Healthy Volunteers
Catholic University of the Sacred Heart
Not applicable
120
Milan
2026-05-10
Recruiting
Università Vita-Salute San Raffaele
Observational
300
Bergamo, Milan
2026-05-08
Recruiting
Mirati Therapeutics Inc.
Phase 2
170
Meldola, Pesaro, Orbassano, Rome, Florence, Perugia, Bologna, Milan
2026-05-06
Recruiting
European Institute of Oncology
Observational
175
Milan
2026-05-06
Recruiting
EMD Serono Research & Development Institute, Inc.
Phase 3
1,020
Castellana Grotte, San Giovanni Rotondo, Milan, Naples, Padova, Pisa, Rome
2026-05-06
Recruiting
Merck Sharp & Dohme LLC
Phase 3
876
Bergamo, Milan, Florence, Perugia, Novara, Roma
2026-05-04
Recruiting
Eli Lilly and Company
Phase 2
60
Florence, Milan, Monza, Negrar, Roma, Rozzano
2026-05-04
Recruiting
Eli Lilly and Company
Phase 2
60
Florence, Milan, Monza, Negrar, Roma, Rozzano
2026-05-04
Recruiting
AstraZeneca
Phase 3
670
Milan, Misterbianco, Naples, Negrar, Reggio Emilia, Rozzano
2026-05-04
Recruiting
Pfizer
Phase 3
2,400
Milan, Bari, Foggia
2026-05-04
Recruiting
Centro Cardiologico Monzino
Observational
66
Milan
2026-05-04
Recruiting
ATLG Levels in Autologous HSCT for Multiple Sclerosis
NCT07635693Multiple Sclerosis, Autologous Hematopoietic Stem Cell Transplant, ATLG
Ciceri Fabio
Observational
20
Milan
2026-05-04
Recruiting
A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008)
NCT07519772Lymphoma, Non-Hodgkin, Lymphoma, Follicular, Lymphoma, Large B-Cell, Diffuse
DrugMK-1045
Merck Sharp & Dohme LLC
Phase 1/2
280
Campania, Candiolo, Milan, Roma
2026-05-03
Not yet open
IRCCS San Raffaele
Observational
400
Milan
2026-05-01
Not yet open
Ultrasound Measurement of Thyroid Volume in Term Newborns
NCT07579988Thyroid Volume, Thyroid Ultrasound, Congenital Hypothyroidism, Healthy Newborns
IRCCS Ospedale San Raffaele
Observational
400
Milan
2026-05-01
By invitation
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
25
Milan
2026-05-01
Not yet open
Making Antibody Treatments More Effective in Early Alzheimer's Disease Using 3Tesla Magnetica Resonance
NCT07456462Alzheimer Dementia (AD), Mild Cognitive Impairment (MCI)
IRCCS San Raffaele
Not applicable
50
Milan
2026-05-01
Active, closed
IRCCS Ospedale San Raffaele
Observational
200
Milan
2026-05-01
Not yet open
Cognitive Impairment Assessment in Breast Cancer Survivors
NCT07582770Cancer Related Cognitive Impairment, Breast Cancer Survivors
European Institute of Oncology
Observational
200
Milan
2026-05
Not yet open
Association for Innovation and Biomedical Research on Light and Image
Observational
1,500
Milan, Novara
2026-05
Not yet open
Fondazione Italiana Linfomi - ETS
Not applicable
170
Ancona, Avellino, Aviano, Bari, Brescia, Cagliari, Florence, Milan
2026-05
Recruiting
Portal Therapeutics, Inc.
Observational
50
Milan, Modena
2026-04-30
Not yet open
IRCCS San Raffaele
Not applicable
33
Milan
2026-04-30
Not yet open
Mario Negri Institute for Pharmacological Research
Phase 2
150
Milan
2026-04-30
Recruiting
Innate srl
Not applicable
25
Milan
2026-04-30
Recruiting
Leal Therapeutics, Inc
Phase 1/2
56
Milan, Torino
2026-04-29
Recruiting
Giovanna Zamboni
Not applicable
75
Milan, Modena
2026-04-28
Recruiting
Hoffmann-La Roche
Phase 3
360
Naples, Milan, Rozzano, Florence
2026-04-27
Recruiting
Centro Cardiologico Monzino
Observational
1,157
Milan
2026-04-27
Recruiting
Merck Sharp & Dohme LLC
Phase 3
590
Rozzano, Naples, Orbassano, Verona, Arezzo, Genova, Milan, Roma
2026-04-23
Recruiting
Curis, Inc.
Phase 2
108
Milan, Novara, Padova
2026-04-23
Recruiting
Fondazione Don Carlo Gnocchi ETS
Not applicable
120
Milan
2026-04-22
Recruiting
Janssen Research & Development, LLC
Phase 3
530
Bologna, Bolzano, Genova, Milan, Roma, Rozzano, Torino
2026-04-21
Recruiting
Establishing a Reference Framework for Outcomes After Machine-Preserved Liver Transplantation in Europe
NCT07585890End-stage Liver Disease (ESLD), Acute Liver Failure, Liver Cirrhosis, Liver Transplantation
University Medical Center Groningen
Observational
10,000
Bari, Bergamo, Bologna, Milan, Pisa, Roma, Torino, Verona
2026-04-21
Recruiting
Ionis Pharmaceuticals, Inc.
Phase 3
20
Milan, Padova, Roma, San Donato Milanese
2026-04-21
By invitation
BioMarin Pharmaceutical
Phase 2
18
Milan, Rome
2026-04-20
Recruiting
Transcultural Digital Solutions in Phase III Cardiac Rehabilitation
NCT07252856Heart Failure, Myocardial Infarction
Fondazione Don Carlo Gnocchi ETS
Not applicable
306
Castellanza, Lumezzane, Milan
2026-04-20
Recruiting
Novo Nordisk A/S
Phase 3
400
Udine, Rome, Milan, San Donato Milanese, Verona
2026-04-20
Recruiting
BioMarin Pharmaceutical
Phase 2/3
160
Genova, Milan
2026-04-20
Recruiting
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Phase 3
420
Bologna, Florence, Milan, Naples, Pisa, Prato, Roma, Rome
2026-04-17
Recruiting
A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers
NCT07226843Lymphoma, Non-Hodgkin's, Lymphoma, Diffuse Large B-Cell, Follicular Lymphoma
DrugRituximab
Eli Lilly and Company
Phase 1
460
Bologna, Milan
2026-04-17
Recruiting
Jiangsu HengRui Medicine Co., Ltd.
Phase 3
150
Bari, Milan, Pavia
2026-04-16
Recruiting
AstraZeneca
Observational
200
Ancona, Bergamo, Foggia, Meldola, Milan, Modena, Naples, Padova
2026-04-16
Recruiting
Mediar Therapeutics
Phase 2
85
Ancona, Catania, Genoa, Milan, Modena, Roma
2026-04-16
Recruiting
ETOP IBCSG Partners Foundation
Phase 2
48
Meldola, Milan, Perugia, Roma
2026-04-15
Recruiting
KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases
NCT06451757Mitochondrial Diseases, Maternally Inherited Diabetes and Deafness (MIDD), Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS), Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation
DrugSonlicromanol
Khondrion BV
Phase 3
220
Milan
2026-04-14
Recruiting
DETERMINANTS OF IMMUNOTHERAPY EFFICACY IN ENDOMETRIAL CANCER
NCT07690540Endometrial Cancer, Immune Checkpoint Inhibitors
European Institute of Oncology
Not applicable
510
Milan
2026-04-14
Recruiting
Regeneron Pharmaceuticals
Phase 2
120
Milan, Pieve Emanuele
2026-04-14
Recruiting
Gruppo Oncologico Italiano di Ricerca Clinica
Observational
100
Bari, Bergamo, Bologna, Misterbianco, Monza, Milan, Modena, Padova
2026-04-14
Active, closed
Novo Nordisk A/S
Phase 3
638
Bologna, Rome, Milan, Palermo
2026-04-13
Recruiting
Fondazione Don Carlo Gnocchi ETS
Not applicable
326
Milan
2026-04-13
Recruiting
AstraZeneca
Phase 3
245
Brescia, Catania, Ferrara, Florence, Milan, Padova, Pisa, Roma
2026-04-13
Recruiting
Novo Nordisk A/S
Phase 3
400
Naples, Modena, Udine, Rome, Milan, San Donato Milanese, Verona
2026-04-13
Recruiting
Istituti Clinici Scientifici Maugeri SpA
Observational
200
Milan
2026-04-10
Recruiting
Incyte Corporation
Phase 3
588
Bologna, Brescia, Candiolo, Foggia, Milan, Naples, Pisa, Roma
2026-04-09
Recruiting
Merck Sharp & Dohme LLC
Phase 3
758
Meldola, Rozzano, Catselfranco Veneto, Florence, Bari, Bologna, Milan, Perugia
2026-04-09
Recruiting
Hoffmann-La Roche
Phase 2
80
Naples, Meldola, Rome, Bergamo, Milan
2026-04-07
Recruiting
River 2 Renal Corp.
Phase 2
430
Milan
2026-04-07
Recruiting
Metabolomics and Transcriptomics of Low- and High-Grade Gliomas
NCT07832734IDH Wildtype Glioblastoma, IDH Mutant Lower-Grade Gliomas
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
220
Milan
2026-04-01
Not yet open
Oral Health, Dento-facial Condition and OHRQoL in Subjects With Mowat-Wilson Syndrome: an Epidemiologic Study.
NCT07476417Mowat-Wilson Syndrome, Dental Caries, Periodontal Diseases, Sleep Related Breathing Disorder
University of Milan
Observational
25
Milan
2026-04-01
Not yet open
IRCCS San Raffaele
Observational
50
Milan
2026-04-01
Recruiting
Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap?
NCT07295522Heart Failure, Acute Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure With Preserved Ejection Fraction (HFPEF)
DrugGDMT
IRCCS Policlinico S. Donato
Phase 4
368
San Donato Milanese, Ancona, Cecina, Ferrara, Florence, Milan, Pisa, Ravenna
2026-03-31
Recruiting
Comprehensive LEFt Atrial Appendage Occlusion With Rhythm Restoration
NCT07523620Atrial Fibrillation (AF), Paroxysmal AF, Persistent Atrial Fibrillation
Abbott Medical Devices
Not applicable
240
Milan
2026-03-31
Recruiting
ASST Fatebenefratelli Sacco
Not applicable
60
Milan
2026-03-31
Recruiting
University of Turin, Italy
Not applicable
820
Rozzano, Bologna, Florence, Foggia, Genova, Milan, Modena, Naples
2026-03-30
Recruiting
InRAD Observational Study
NCT07213700Alzheimer's Disease(AD), Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD), Non-Alzheimer Degenerative Dementia
Stichting International Registry for Alzheimer's Disease and other Dementias Foundation
Observational
50,000
Foggia, Milan
2026-03-30
Recruiting
Bristol-Myers Squibb
Phase 1/2
474
Verona, Milan, Napoli Campania
2026-03-26
Recruiting
European Institute of Oncology
Not applicable
150
Milan
2026-03-26
Recruiting
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
NCT07415044Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate, Ulcerative Colitis, Active Severe
DrugZotemtegrast
Eli Lilly and Company
Phase 2
1,431
Milan, Rho, Rome, Rozzano
2026-03-26
Recruiting
Transition to KPL-387 Monotherapy Dosing & Administration Study
NCT07288216Recurrent Pericarditis, Heart Diseases, Pericarditis
DrugKPL-387
Kiniksa Pharmaceuticals International, plc
Phase 2
120
Florence, Genoa, Milan, Padua, Udine, Varese
2026-03-25
Recruiting
Zanubritnib and Anti-MAG Neuropathy
NCT07392229Anti-MAG IgM-associated Demyelinating Polyneuropathy
DrugZanubrutinib
Azienda Ospedaliera di Padova
Phase 2
50
Milan, Padova, Pavia, Roma, Torino, Trieste
2026-03-24
Recruiting
Novartis Pharmaceuticals
Phase 3
770
Bologna, Brescia, Milan
2026-03-24
Recruiting
Hoffmann-La Roche
Phase 3
1,600
Bergamo, Catanzaro, Bologna, Rome, Milan, Palermo, Perugia
2026-03-23
Recruiting
Amgen
Phase 3
406
Ferrara, Milan, San Donato Milanese, Torino
2026-03-23
Recruiting
Boehringer Ingelheim
Phase 2
132
Ancona, Bari, Bologna, Messina, Milan, Pavia, San Giovanni Rotondo (FG), Verona
2026-03-23
Recruiting
Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure
NCT07219459Unresectable or Metastatic Hepatocellular Carcinoma, Child-Pugh A Hepatocellular Carcinoma, Failure of First-Line Treatment That Included an Approved Anti PD-(L)1 Compound
DrugsVisugromab RDE·Visugromab·Opdivo·Lenvatinib
CatalYm GmbH
Phase 2
104
Bologna, Milan, Ravenna
2026-03-19
By invitation
Effects of Trophectoderm (TE) Biopsy on the Health and Development of Children Born After Preimplantation Genetic Testing (PGT) Cycles.
NCT07349966Preimplantation Genetic Testing (PGT), Frozen Embryo Transfer Cycle, Assisted Reproduction Technologies, Postnatal Health
IRCCS San Raffaele
Observational
330
Milan
2026-03-19
Recruiting
Merck Sharp & Dohme LLC
Phase 3
400
Milan, Roma
2026-03-18
Recruiting
Bristol-Myers Squibb
Phase 3
850
Naples, Ravenna, Aviano, Orbassano, Rome, Milan, Parma
2026-03-16
Recruiting
Bristol-Myers Squibb
Phase 1/2
198
Meldola, Pisa, Milan
2026-03-16
Not yet open
IRCCS San Raffaele
Not applicable
134
Milan
2026-03-15
Recruiting
Bristol-Myers Squibb
Phase 2/3
690
Naples, Turin, Padova, Milan, Roma
2026-03-13
Recruiting
High Resolution Imaging OCT Study
NCT07338461Normal Eyes, Age Related Macular Degeneration, Diabetic Retinopathy, Eyes With Retinal Diseases
Heidelberg Engineering GmbH
Not applicable
97
Milan
2026-03-13
Recruiting
Sanofi
Phase 2/3
526
Torette, Milan, Rome, Bologna, Brescia, Novara, Palermo
2026-03-13
Recruiting
Bristol-Myers Squibb
Phase 3
750
Ferrara (Cona), Aviano, Catania, Candiolo, Genova, Milan, Naples, Novara
2026-03-12
Recruiting
Astellas Pharma Global Development, Inc.
Phase 2
240
Bari, Foggia, Meldola, Milan
2026-03-12
Recruiting
Hoffmann-La Roche
Phase 2
100
Rome, Milan, Castelfranco Veneto
2026-03-11
Recruiting
Hoffmann-La Roche
Phase 2
360
Chieti, Naples, Salerno, Roma, Genoa, Milan, Pavia
2026-03-10
By invitation
Early Detection of Cerebral Palsy Subtype
NCT07916519Cerebral Palsy, Early Assessment, Early Rehabilitation Intervention
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
30
Milan
2026-03-10
Recruiting
GREENWATER 2.0: Reducing Iodinated Contrast Agents in Hospital Wastewater
NCT07620093Environmental Sustainability in Radiology, Iodinated Contrast Agent Recovery
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
416
Milan
2026-03-10
Recruiting
PRospective Registry of Esophageal Motility
NCT07506746Esophageal Diseases, Achalasia, Eosinophilic Esophagitis, Motility Disorder
IRCCS San Raffaele
Observational
10,000
Milan
2026-03-09
Recruiting
Novartis Pharmaceuticals
Phase 2
272
Florence, Milan, Roma
2026-03-09
Recruiting
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
NCT07491445Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma
DrugsCetuximab·Nab-paclitaxel·Gemcitabine
Revolution Medicines, Inc.
Phase 3
900
Milan, Padova, Roma, Tricase, Verona
2026-03-09
Recruiting
Novartis Pharmaceuticals
Phase 2
210
Ancona, Cona, Milan, Rozzano
2026-03-09
Recruiting
Incyte Corporation
Phase 3
700
Ancona, Aviano, Bari, Brescia, Candiolo, Catania, Milan, Naples
2026-03-05
Recruiting
Janssen Research & Development, LLC
Phase 3
600
Ancona, Catania, Milan, Perugia, Roma, Rozzano, Torino, Udine
2026-03-05
Recruiting
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Observational
300
Milan
2026-03-05
Recruiting
Alexion Pharmaceuticals, Inc.
Phase 4
75
Milan, Naples, Rome
2026-03-04
Active, closed
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398Pulmonary Hypertension Associated With HFpEF
DrugTNX-103
Tenax Therapeutics, Inc.
Phase 3
540
Acquaviva delle Fonti, Bergamo, Messina, Milan, Pavia, Pisa, Roma, Rozzano
2026-03-03
Recruiting
IRCCS San Raffaele
Observational
100
Milan
2026-03-02
Not yet open
IRCCS San Raffaele
Observational
35
Milan
2026-03-01
Not yet open
EIT- Guided Lung Recruitment in pARDS
NCT07402174Acute Respiratory Distress Syndrome
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
8
Milan
2026-03-01
Recruiting
Ospedale San Raffaele
Not applicable
100
Milan
2026-03-01
Recruiting
Derivation and Validation of the Aortic Valve Echocardiographic Calcium Score to Confirm Severe Aortic Stenosis: the Echo-AVCS Study
NCT07620925Aortic Stenosis, Chronic Coronary Syndrome, Calcific Aortic Valve Disease, Calcific Aortic Stenosis
Azienda Ospedaliera "Sant'Andrea"
Observational
250
Bologna, Milan, Roma
2026-03-01
Not yet open
Humanitas Hospital, Italy
Observational
226
Milan, Brescia, Roma
2026-03
Not yet open
Spinal Cord Stimulation Combined With Motor Training in Non-Traumatic SCI: A Prospective Interventional Study
NCT07412808Spinal Cord Disease, Spinal Cord Injuries (Complete and Incomplete)
Albano Luigi
Not applicable
10
Milan
2026-03
Active, closed
MICROVASCULAR DAMAGE IN THROMBOTIC THROMBOCYTOPENIC PURPURA
NCT07615244TTP - Thrombotic Thrombocytopenic Purpura
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
79
Milan
2026-02-28
Recruiting
Progel Platinum for Air Leak Reduction After VATS Lobectomy for NSCLC
NCT07479277Non-Small Cell Lung Cancer, Postoperative Air Leak, NSCLC
Fondazione del Piemonte per l'Oncologia
Not applicable
160
Candiolo, Bolzano, Florence, Milan, Palermo, Pisa
2026-02-27
Recruiting
Mirum Pharmaceuticals, Inc.
Phase 2/3
120
Bergamo, Milan
2026-02-26
Recruiting
IRCCS Ospedale San Raffaele
Phase 2
38
Milan
2026-02-25
Recruiting
Real-life Ecological Momentary Assessment of Lived Burden in Hereditary AngioEdema
NCT07448181Hereditary Angioedema With C1 Esterase Inhibitor Deficiency, Hereditary Angioedema - Type 1, Hereditary Angioedema - Type 2
Istituti Clinici Scientifici Maugeri SpA
Observational
30
Milan
2026-02-23
Recruiting
AstraZeneca
Phase 3
508
Bologna, Milan, Naples, Rozzano, Torino
2026-02-23
Not yet open
University of Rome Tor Vergata
Observational
220
Milan
2026-02-20
Recruiting
Ceric Sàrl
Not applicable
140
Milan
2026-02-18
Recruiting
Crescent Biopharma, Inc.
Phase 1/2
540
Candiolo, Florence, Milan
2026-02-17
Recruiting
Genmab
Phase 1
78
Bergamo, Milan, Pisa
2026-02-16
Recruiting
Casa di Cura IGEA
Not applicable
40
Milan
2026-02-16
Recruiting
Merck Sharp & Dohme LLC
Phase 3
900
Brescia, Lecco, Milan, Padova, Roma, Torino
2026-02-16
Recruiting
Boehringer Ingelheim
Phase 3
286
Bari, Bologna, Milan, Palermo, Pavia, Varese
2026-02-16
Not yet open
TRacheal Cuff PRessure Evaluation Study
NCT06848010Pneumonia, Ventilator-Associated, Mechanical Ventilation
Policlinico Hospital
Not applicable
54
Milan
2026-02-15
Recruiting
Kardigan, Inc.
Phase 2/3
332
Bari, Florence, Milan, Padova, Pavia, Roma, Rozzano, Trieste
2026-02-13
Recruiting
Elion Therapeutics, Inc.
Phase 2
60
Milan, Roma
2026-02-13
Recruiting
Bayer
Phase 4
50
Lecce, Bologna, Bergamo, Milan, Pavia, Florence, Pisa, Siena
2026-02-13
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
116
Milan
2026-02-11
Recruiting
ViiV Healthcare
Phase 2
186
Bergamo, Milan, Roma
2026-02-11
Recruiting
Digital Twin and Ml-basEd MOdel of TEVAR Interventions
NCT07640828Aorta Disease, Aorta, Thoracic Pathologies
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
5,000
Milan
2026-02-11
Recruiting
Pfizer
Phase 2/3
1,156
Bergamo, Reggio Emilia, Cona, Milan, Roma
2026-02-11
Recruiting
Zealand Pharma
Phase 3
90
Rome, Milan, Padova
2026-02-11
Recruiting
AstraZeneca
Phase 2
124
Milan, Padua, Roma, Rozzano
2026-02-10
Recruiting
A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis
NCT07201922Familial Pulmonary Fibrosis, Interstitial Lung Abnormalities, Interstitial Lung Diseases
DrugNerandomilast
Boehringer Ingelheim
Phase 3
80
Milan, Padova, Roma
2026-02-10
Recruiting
ImmunAbs Inc.
Phase 1/2
96
Brescia, Milan
2026-02-05
Recruiting
Janssen Research & Development, LLC
Phase 3
400
Alessandria, Brescia, Milan, Naples, Pisa, Reggio Emilia, Roma, Rozzano
2026-02-04
Recruiting
AstraZeneca
Phase 3
2,130
Meldola, Milan, Padova, Rozzano, Tricase
2026-02-03
Recruiting
Fall Risk in Adults Over 65: The Relevance of Morphological and Functional Lower Limb Asymmetries.
NCT07742397Aging, Asymmetry, Fall Risk Factors, Fall Prevention
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
90
Milan
2026-02-03
Recruiting
Alnylam Pharmaceuticals
Phase 3
125
Florence, Milan, Padova, Pavia, Roma
2026-02-03
Recruiting
European Institute of Oncology
Observational
50
Milan
2026-02-02
Recruiting
Exciva GmbH
Phase 2/3
300
Rome, Tricase, Brescia, Milan, Palermo, Chieti
2026-02-02
Recruiting
University of Milan
Not applicable
126
Milan, Urbino
2026-02-01
Recruiting
Lombard Cohort of Brain Health Services
NCT07457138Subjective Cognitive Decline (SCD), Functional Cognitive Disorder, Alzheimer's Disease, Brain Health
University of Milano Bicocca
Observational
1,000
Costa Masnaga, Milan, Monza, San Donato Milanese
2026-02-01
Recruiting
Istituto Auxologico Italiano
Not applicable
48
Milan
2026-02-01
Recruiting
Prilenia
Phase 3
500
Caserta, Milan, Modena, Padova, Torino
2026-02-01
Recruiting
Wooshin Labottach Co., Ltd.
Phase 3
72
Milan
2026-02
Recruiting
Transcatheter Mitral and Tricuspid Interventions: a Cardiac Magnetic Resonance Study
NCT07370467Mitral Insufficiency, Transcatheter Aortic Valve Replacement
Centro Cardiologico Monzino
Observational
250
Milan
2026-01-30
Recruiting
Merck Sharp & Dohme LLC
Phase 1/2
170
Meldola, Milan, Roma
2026-01-29
Recruiting
Delcath Systems Inc.
Phase 2
90
Milan
2026-01-29
Active, closed
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
35,500
Milan
2026-01-29
Recruiting
Targeting Real World Usage In Stroke Treatment
NCT07474935Saccular and Fusiform Aneurysms, Pseudoaneurysm, Vascular Dissection, Perforation
Phenox GmbH
Observational
5,000
Catania, Milan, Naples
2026-01-29
Recruiting
Germline Genetic Testing of the TP53 Gene
NCT07419893TP53 Gene Mutation, Multi-Gene Transcriptional Profiling, TP53 Gene Germline Mutation Carrier
European Institute of Oncology
Observational
1,940
Milan
2026-01-29
Recruiting
Upfront Targeted Axillary Dissection for Luminal Breast Cancer With Limited Axillary Involvement
NCT07278726ALND, Sentinel Lymph Node Biopsy (SLNB), Targeted Axillary Dissection (TAD)
European Institute of Oncology
Observational
150
Bologna, Forlì, Milan, Naples, Ortona, Pavia, Pisa, Roma
2026-01-28
Recruiting
IDEAYA Biosciences
Phase 3
520
Naples, Milan, Perugia, Florence, Pisa, Rome
2026-01-25
Not yet open
European Institute of Oncology
Not applicable
20
Milan
2026-01-22
Recruiting
BeOne Medicines
Phase 3
500
Bologna, Florence, Milan, Padova, Roma
2026-01-22
Recruiting
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)
NCT07159841Congenital Adrenal Hyperplasia, Classic Congenital Adrenal Hyperplasia
DrugAtumelnant
Crinetics Pharmaceuticals Inc.
Phase 2/3
153
Naples, Genoa, Milan, Florence
2026-01-22
Active, closed
CSL Behring
Phase 2
84
Brindisi, Milan, Modena, Monza, Naples, Verona
2026-01-22
Not yet open
IMMUNOTHERAPY EFFICACY TARGETING ENDOMETRIAL CANCER
NCT07374809Endometrial Carcinoma (EC), pMMR, DMMR Cancer
European Institute of Oncology
Not applicable
50
Milan
2026-01-21
Recruiting
Sexual Well-being of Women Undergoing Mastectomy and Reconstruction
NCT07234461Mastectomy and Breast Reconstruction, Sexual Wellness
European Institute of Oncology
Not applicable
200
Bari, Bologna, Cesena, Forlì, Milan, Olbia, Padova, Palermo
2026-01-21
Recruiting
Prevalence of Mild Cognitive Impairment and Dementia in Patients Admitted to Non-neurological Rehabilitation Wards
NCT07731334MCI, Mild Cognitive Impairment (MCI), Mild Cognitive Impairment, Cognitive Deficit
Fondazione Don Carlo Gnocchi ETS
Not applicable
384
Florence, Milan
2026-01-20
Not yet open
Validation and Cultural Adaptation of the KOOS-ACL Scale for the Italian Population
NCT07386405Scale Reliability Validity, ACL Injury, Validation and Cultural Adaptation of a Scale, PROMs
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
120
Milan
2026-01-19
Recruiting
Merck Sharp & Dohme LLC
Phase 3
1,023
Meldola, Aviano, Milan, Brescia, Catania, Padova, Roma, Torino
2026-01-19
Recruiting
Boehringer Ingelheim
Phase 3
400
Bari, Milan, Misterbianco (CT), Naples, Orbassano (TO), Roma, Rozzano (MI), Verona
2026-01-16
Recruiting
IRCCS Centro San Giovanni di Dio Fatebenefratelli
Not applicable
72
Brescia, Milan
2026-01-15
Not yet open
Luspatercept in Patients Affected With Rare Inherited Anemias
NCT07331818Hereditary Red Blood Cell Disorder (Disorder)
DrugReblozyl
EuroBloodNet Association
Phase 2
45
Milan
2026-01-15
Recruiting
Sanofi
Phase 3
160
Montichiari, Milan, Rozzano, Cagliari, Foggia, Roma
2026-01-14
Recruiting
University of Milan
Not applicable
12
Milan
2026-01-13
Recruiting
Novartis Pharmaceuticals
Observational
50
Alessandria, Avellino, Brescia, Florence, Genova, Milan, Palermo, Roma
2026-01-13
Recruiting
Eli Lilly and Company
Phase 3
150
Ancona, Bologna, Cagliari, Florence, Milan, Naples, Novara, Padova
2026-01-12
Recruiting
ASST Fatebenefratelli Sacco
Not applicable
52
Milan
2026-01-12
Recruiting
ETOP IBCSG Partners Foundation
Phase 3
390
Meldola, Milan, Novara, Pavia, Perugia, Prato, Siena, Treviso
2026-01-12
Recruiting
Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO IV-EPIC 38)
NCT06535568Coronary Disease, Heart Diseases, Cardiovascular Diseases, Myocardial Ischemia
DrugDAPT
Fondazione Ricerca e Innovazione Cardiovascolare ETS
Not applicable
576
Milan
2026-01-10
Recruiting
Incyte Corporation
Phase 1
280
Bologna, Milan, Rome, Verona
2026-01-08
Recruiting
Novo Nordisk A/S
Phase 3
460
Milan, Novara, Verona, Trieste
2026-01-08
Recruiting
Istituti Clinici Scientifici Maugeri SpA
Observational
419
Bari, Milan, Pavia, Torino, Veruno
2026-01-08
By invitation
Medtronic
Observational
2,000
Bologna, Milan
2026-01-07
By invitation
Istituto Clinico Humanitas
Observational
60
Milan
2026-01-07
Recruiting
Insmed Incorporated
Phase 3
344
Bologna, Catania, Milan, Modena, Monza, Naples, Pavia, Roma
2026-01-07
Recruiting
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
NCT07222566Advanced Non-Small Cell Lung Cancer, Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC)
DrugsPF-08634404·Pembrolizumab
Pfizer
Phase 3
1,410
Naples, Misterbianco, Meldola, Milan, Fano, Aviano, Roma, Brescia
2026-01-06
Recruiting
Bristol-Myers Squibb
Phase 2/3
590
Naples, Ravenna, Aviano, Orbassano, Siena, Perugia, Bologna, Milan
2026-01-02
Not yet open
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Observational
100
Milan
2026-01-01
Not yet open
FMRI Study on DC/TMD Patients
NCT07259902TMJ Disorder
University of Milan
Not applicable
60
Milan
2026-01-01
Active, closed
COMBINED PSMA-PET/CT AND MRI STAGING IN INTERMEDIATE AND HIGH-RISK PATIENTS PROSTATA-CANCER (COMBINE-P)
NCT07455097Intermediate-risk Prostate Cancer, High-risk Prostate Cancer
Heinrich-Heine University, Duesseldorf
Observational
600
Milan
2026-01-01
Not yet open
Inherited Retinal Diseases: Natural History and Genotype-Phenotype Correlations
NCT07265895Retinal Degenerations, Retinitis Pigmentosa (RP), Stargardt Disease
IRCCS San Raffaele
Observational
200
Milan
2026-01-01
Recruiting
CompArative Analysis Between, Thymic, pulmonaRy and Pancreatic Well Differentiated High Grade Neuroendocrine Tumors
NCT07429851Neuroendocrine Carcinoma of Lung, Neuroendocrine Carcinoma of Thymus
European Institute of Oncology
Observational
34
Milan
2026-01-01
Recruiting
Niguarda Hospital
Observational
270
Milan
2026-01-01
By invitation
Autoimmune Hyperthyroidism in Prepubertal Children
NCT07544290Autoimmune Hyperthyroidism, Children
IRCCS Ospedale San Raffaele
Observational
100
Milan
2026-01-01
Recruiting
Istituto Clinico Humanitas
Observational
53
Milan, Rozzano
2026-01
Not yet open
Analysis of the Presence and Cardiac Functional Effects of Anti-NaV1.5 Autoantibodies in Patients With Metastatic Tumors
NCT07364656Brugada Syndrome (BrS), Breast Cancer Females, Colon Cancer, ECG Abnormalities
IRCCS Policlinico S. Donato
Not applicable
196
Milan
2026-01
Recruiting
Bristol-Myers Squibb
Phase 2/3
990
Castellana Grotte, San Giovanni Rotondo, Tricase, Milan, Aviano, Pisa, Padova, Avellino
2025-12-31
Recruiting
Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
NCT07288359Advanced HR+/HER2- Breast Cancer, Advanced CCNE1-amplified Solid Tumors, Metastatic Castration-resistant Prostate Cancer
DrugsLetrozole·Fulvestrant
Novartis Pharmaceuticals
Phase 1/2
205
Milan
2025-12-29
Recruiting
AstraZeneca
Phase 3
1,100
Brescia, Catania, Florence, Lecco, Milan, Naples, Parma, Pisa
2025-12-29
Recruiting
Sanofi
Phase 2
144
Torette, Cona, Garbagnate Milanese, Milan, Brescia, Chieti, Pisa
2025-12-29
Recruiting
Norgine
Phase 3
212
Bergamo, Florence, Messina, Milan, Naples, Roma
2025-12-29
Recruiting
Incyte Corporation
Phase 2
56
Bologna, Brescia, Meldola, Milan, Naples, Padova, Roma
2025-12-29
Recruiting
European Myeloma Network B.V.
Phase 3
1,000
Ancona, Cuneo, Florence, Genova, Legnano, Meldola, Milan, Reggio
2025-12-23
Recruiting
Eli Lilly and Company
Phase 3
800
Bergamo, Bologna, Florence, Genova, Meldola, Milan, Misterbianco, Monza
2025-12-22
Recruiting
Janssen Research & Development, LLC
Phase 3
800
Florence, Localita La Schiana Pozzuoli, Milan, Roma, Torino
2025-12-19
Active, closed
Safety, Performance, and Clinical Benefit of Pacing the Left Bundle Branch Area - Post-Market Clinical Follow-up
NCT07209852Bradycardia, Atrioventricular Block, Sinus Node Dysfunction, Bundle-Branch Block
Boston Scientific Corporation
Observational
140
Ferrara, Milan, Novara
2025-12-19
Recruiting
Merck Sharp & Dohme LLC
Phase 2
140
Milan
2025-12-19
Recruiting
argenx
Phase 2
70
Bergamo, Milan, Naples
2025-12-19
Recruiting
argenx
Observational
70
Bergamo, Milan, Naples
2025-12-19
Recruiting
Ibrutinib Plus Venetoclax Long-Term Outcomes in CLL
NCT07774390Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)
European Research Initiative on CLL
Observational
323
Milan
2025-12-18
Recruiting
Molecular Phenotyping of Primitive Lung Cancer and Metastatic Site
NCT07325864NSCLC, Lung Cancer (Diagnosis)
European Institute of Oncology
Observational
25
Milan
2025-12-18
Recruiting
Sanofi
Phase 3
85
Florence, Milan, Rozzano
2025-12-18
Recruiting
A Study on Hemolytic Disease of the Fetus and Newborn (HDFN) Through Global Registry
NCT07194070Hemolytic Disease of the Fetus and Newborn
Janssen Research & Development, LLC
Observational
175
Milan, Roma
2025-12-17
Active, closed
WATCHMAN FLX Pro European Registry
NCT07262255Non-valvular Atrial Fibrillation (AF), Left Atrial Appendage Closure
Boston Scientific Corporation
Observational
189
Catania, Milan, Verona
2025-12-17
Recruiting
ArriVent BioPharma, Inc.
Phase 3
480
Aviano, Milan
2025-12-17
Recruiting
MitrAl Valve Calcium aSsEssmEnt With TrueVue Trans-illumination 3D Rendering.
NCT07612553Mitral Annular Calcification, Mitral Valve Disease
Centro Cardiologico Monzino
Observational
100
Milan
2025-12-17
Not yet open
Efficacy and Safety of 7 Millimeters Vaginal Radiofrequency in Overactive Bladder
NCT07279142Overactive Bladder (OAB), Incontinence, Urge
IRCCS San Raffaele
Not applicable
48
Milan
2025-12-16
Recruiting
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
NCT07252232Pancreatic Cancer, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Ductal Adenocarcinoma (PDAC)
DrugCetuximab
Revolution Medicines, Inc.
Phase 3
500
Milan, Naples, Padova, Pisa, Verona
2025-12-15
Recruiting
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
NCT07218380Carcinoma, Transitional Cell, Urinary Bladder Neoplasms, Neoplasm Metastasis
DrugsVepugratinib·Pembrolizumab
Eli Lilly and Company
Phase 3
450
Bari, Milan, Naples, Padova, Pisa, Roma, Rome
2025-12-12
Recruiting
Merck Sharp & Dohme LLC
Phase 2
180
Ravenna, Milan, Roma
2025-12-12
Recruiting
European Myeloma Network B.V.
Phase 2
150
Ascoli Piceno, Bari, Bergamo, Bologna, Bolzano, Como, Milan, Novara
2025-12-12
Recruiting
Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in IBC
NCT07080944Invasive Breast Carcinoma, Sentinel Lymph Node Biopsy (SLNB), Neoadjuvant Chemotherapy
European Institute of Oncology
Not applicable
75
Milan
2025-12-12
Active, closed
BaLloon-based PFA Ablation poST Approval Outcomes for PAF and PersAF
NCT07181590Paroxysmal AF, Atrial Arrhythmia, Atrial Fibrillation, Persistent Atrial Fibrillation
Abbott Medical Devices
Not applicable
300
Ancona, Milan
2025-12-11
Recruiting
Pfizer
Phase 3
800
Tricase, Roma, Padova, Florence, Milan
2025-12-11
Recruiting
Pharmanutra S.p.a.
Not applicable
144
Milan, Roma, Rozzano
2025-12-11
Recruiting
A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
NCT07144163Congenital Adrenal Hyperplasia, Classic Congenital Adrenal Hyperplasia
DrugAtumelnant
Crinetics Pharmaceuticals Inc.
Phase 3
150
Genova, Milan, Rozzano, Modena, Padova, Palermo, Naples, Roma
2025-12-11
Recruiting
BeOne Medicines
Phase 1
86
Milan, Naples, Roma, Rozzano
2025-12-11
Recruiting
AbbVie
Phase 2/3
490
Milan, Monza, Fano, Aviano, Rome, Candiolo, Catania, Verona
2025-12-10
Active, closed
Italian Real-World Study of Epcoritamab in Relapsed or Refractory DLBCL
NCT07393204Relapsed Diffuse Large B-cell Lymphoma (DLBCL), Refractory Diffuse Large B-Cell Lymphoma
Andrés José Maria Ferreri
Observational
150
Milan
2025-12-10
Recruiting
ALX Oncology Inc.
Phase 2
120
Torrette, Genova, Bergamo, Bologna, Milan, Monza, Novara
2025-12-10
Active, closed
Boehringer Ingelheim
Phase 3
135
Genova, Milan, Padova, Roma
2025-12-09
Recruiting
PENG Block + LIA For Endoprosthesis Surgery
NCT07239817Hip Fractures, Arthroplasty, Replacement, Hip, Pain, Postoperative, Anesthesia and Analgesia
ASST Gaetano Pini-CTO
Not applicable
100
Milan
2025-12-09
Active, closed
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
1,200
Bologna, Cagliari, Catanzaro, Florence, Milan, Palermo, Potenza, Roma
2025-12-09
Recruiting
Incyte Corporation
Phase 3
466
Alba, Alessandria, Aviano, Bologna, Florence, Lecco, Milan, Mirano
2025-12-09
Recruiting
A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC
NCT07226986PSMA-positive Metastatic Castration Resistant Prostate Cancer (mCRPC) With Prior Exposure to One Prior ARPI Who Are Candidates for Taxane-based Chemotherapy
DrugsAbiraterone·Enzalutamide
Novartis Pharmaceuticals
Phase 1/2
123
Cona, Milan, Naples
2025-12-05
Recruiting
EMDR Integrative Group Protocol and Individual Treatment for Patients With Cancer: A Pilot Study
NCT07447089Thyroid Neoplasms, Neoplasm, Post-traumatic Stress Disorder (PTSD), Psychological Distress
Università Cattolica di Milano
Not applicable
25
Milan
2025-12-05
Recruiting
AstraZeneca
Phase 3
1,100
Castellana Grotte, Milan, Pisa, Rome, Rozzano
2025-12-04
Recruiting
Merck Sharp & Dohme LLC
Phase 2
150
Rozzano, Milan, Roma
2025-12-04
Recruiting
Janssen Research & Development, LLC
Observational
200
Bari, Brescia, Iesi, Milan, Naples, Palermo, Pavia, Perugia
2025-12-04
Recruiting
Janssen Research & Development, LLC
Phase 3
600
Milan, Naples, Palermo, Pavia, Roma, Rozzano
2025-12-03
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Not applicable
1,260
Bari, Bologna, Catania, Ferrara, Milan, Novara, Palermo, Parma
2025-12-03
Recruiting
GlaxoSmithKline
Phase 3
450
Meldola, Rozzano MI, Bari, Bologna, Candiolo, Genova, Milan, Padova
2025-12-03
Recruiting
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Not applicable
200
Milan
2025-12-03
Recruiting
Meyer Children's Hospital IRCCS
Observational
150
Bari, Milan, Naples, Roma, Torino, Florence
2025-12-02
Recruiting
Bristol-Myers Squibb
Phase 3
650
Naples, Rome, Milan, Pisa, Brescia, Isernia, Roma
2025-12-02
Active, closed
Centro Cardiologico Monzino
Not applicable
260
Milan
2025-12-01
Not yet open
Hip Fracture Surgery Arterial and Venous Thrombotic Events Prevention
NCT07228663Hip Fracture Surgery, Cardiovascular Prevention, Venous Thromboembolism (VTE)
DrugsDirect Anticoagulant·Dalteparin·DOAC·Tinzaparin
McMaster University
Phase 3
100
Milan
2025-12-01
Recruiting
Andrés José Maria Ferreri
Observational
25
Milan
2025-12-01
Recruiting
A ELN-Multicenter Study on Phenotypic Evolution and Clinical Outcomes
NCT07203768Polycythemia Vera, Thrombocythemia
FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
Observational
678
Pavia, Vicenza, Alessandria, Bergamo, Bologna, Brescia, Florence, Milan
2025-12-01
Active, closed
The HER Project: HRD in EGFR-mutated NSCLC
NCT07303218EGFR, Non Small Cell Lung Cancer, Homologous Recombination Deficiency, PARP Inhibitor
IRCCS San Raffaele
Observational
100
Milan
2025-12-01
Recruiting
Eli Lilly and Company
Phase 3
7,140
Bologna, Brescia, Ferrara, Florence, Genova, Milan, Monza, Palermo
2025-12-01
Recruiting
Personalized Digital Training for COGnitive FITness in Mild Cognitive Impairment
NCT07286448Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD)
Giovanna Zamboni
Not applicable
100
Modena, Milan
2025-11-28
Recruiting
Amgen
Phase 3
750
Foggia, Milan, Modena, Orbassano, Peschiera del Garda, Rozzano, Trento
2025-11-28
Recruiting
Genmab
Phase 3
660
Bologna, Catania, Meldola, Monza, Milan, Prato, Reggio Emilia
2025-11-28
Recruiting
Hoffmann-La Roche
Phase 3
250
Naples, Cona (Ferrara), Rome, Milan, Novara, Turin, Palermo
2025-11-27
Recruiting
Debiopharm International SA
Phase 3
119
Ferrara, Genova, Milan, Naples, Padova, Roma, Torino
2025-11-26
Recruiting
Merck Sharp & Dohme LLC
Phase 3
904
Naples, Rome, Milan, Rozzano, Orbassano, Florence, Castelfranco Veneto, Peschiera del Garda
2025-11-26
Recruiting
RESOLving INflammation Through Diet for Health (RESOLVIN)
NCT07331103Cardiovascular (CV) Risk, Inflammation, Omega 3
Mario Negri Institute for Pharmacological Research
Not applicable
324
Cortona, Avellino, Arese, Paderno Dugnano, Milan, Palermo, Gubbio, Matera
2025-11-26
Recruiting
AbbVie
Phase 2
180
Milan, Rome, Orbassano, Roma
2025-11-25
Active, closed
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
43,000
Milan
2025-11-25
Recruiting
SAb Biotherapeutics, Inc.
Phase 2
159
Milan, Turin, Verona
2025-11-25
By invitation
Celldex Therapeutics
Phase 3
1,370
San Donato Milanese, Milan, Torino
2025-11-25
Recruiting
Optimal Time for Reperfusion in Acute Pulmonary Embolism
NCT07436702Pulmonary Embolism (Diagnosis), Pulmonary Embolism Acute
Azienda ULSS 8 Berica
Observational
500
Milan, Monselice, Pavia, Perugia, Pisa, Torino, Arzignano
2025-11-25
Recruiting
Hoffmann-La Roche
Phase 3
900
Naples, Salerno, Bologna, Cassino, Rome, Genoa, Brescia, Milan
2025-11-24
Recruiting
A Platform Study in Non-Small Cell Lung Cancer (NSCLC)
NCT06996782Advanced or Metastatic Non-small Cell Lung Cancer
DrugsRamucirumab·Rilvegostomig·Nab-paclitaxel·Pemetrexed
AstraZeneca
Phase 1/2
152
Milan, Orbassano, Pavia, Roma
2025-11-24
Recruiting
Italian Sarcoma Group
Phase 2
20
Candiolo, Milan, Padova, Prato, Roma
2025-11-21
Recruiting
Istituto Auxologico Italiano
Not applicable
439
Milan
2025-11-20
Recruiting
Bayer
Phase 3
111
Bergamo, Bologna, Milan, Naples, Genova, Padova, Roma, Torino
2025-11-19
Active, closed
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen
NCT07087054Carcinoid Syndrome, Carcinoid, Carcinoid Tumor, Carcinoid Tumor of Ileum
Crinetics Pharmaceuticals Inc.
Phase 3
141
Bologna, Milan, Rome, Turin
2025-11-19
Recruiting
European Institute of Oncology
Observational
3
Milan
2025-11-19
Recruiting
Ono Pharmaceutical Co., Ltd.
Phase 2
144
Milan, Naples, Padova
2025-11-18
Recruiting
Summit Therapeutics
Phase 3
900
Roma, Aviano, Brescia, Florence, Genova, Meldola, Milan, Pisa
2025-11-18
Recruiting
Pediatric Upper-Limb Rehabilitation With PhiCube, a Modular Bilateral End-Effector Device
NCT07092436Congenital and Acquired Neuromotor Disorders, Developmental Coordination Disorder (DCD)
Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato
Not applicable
54
Bosisio Parini, Calambrone, Salerno, Genova, Milan, Pavia
2025-11-17
Active, closed
Targeting Immunosuppressive Treatment for Non-infectious Uveitis Using Aqueous Humor Cytokine Profiles
NCT07262437Uveitis Posterior Non-Infectious, Inflammation Eye, Uveitis, Uveitis, Anterior
University of Milan
Not applicable
220
Milan, Reggio Emilia
2025-11-15
Not yet open
Neutrophil Biomarker Test for Predicting Clinical Benefit From Immunotherapy Based on Flow Cytometry Analysis
NCT07246759Non Small Cell Lung Cancer (NSCLC), Melanoma (Skin Cancer), Triple Negative Breast Cancer (TNBC), RCC, Renal Cell Cancer
OncoHost Ltd.
Observational
600
Milan
2025-11-15
Active, closed
Cognitive Alterations in Pulmonary Arterial Hypertension (PAH)
NCT07391228Pulmonary Arterial Hypertension
Alessandra Gorini
Observational
30
Milan
2025-11-15
Recruiting
Incyte Corporation
Phase 3
250
Bologna, Brescia, Catania, Milan, Naples, Padua, Roma, Rome
2025-11-13
Active, closed
Hoffmann-La Roche
Phase 2
193
Foggia, Naples, Rome, Milan, Pozzilli
2025-11-13
Recruiting
Eli Lilly and Company
Phase 2
252
Milan, Roma, Rozzano
2025-11-10
Recruiting
Phase 2 Study of ADX-038 in Participants With Geographic Atrophy
NCT06990269Geographic Atrophy Secondary to Age-related Macular Degeneration
ADARx Pharmaceuticals, Inc.
Phase 2
240
Milan, Roma, Novara, Padova
2025-11-10
Active, closed
Istituto Scientifico Italiano Colonna Vertebrale
Not applicable
178
Milan
2025-11-07
Recruiting
Sanofi
Phase 2
208
Rome, Milan, Rozzano, Catania
2025-11-06
Recruiting
AstraZeneca
Phase 2
435
Milan, Palermo, Pavia, Perugia, Roma, Rozzano, Torrette
2025-11-06
Active, closed
Novo Nordisk A/S
Phase 3
300
Rome, Palermo, Bologna, Milan
2025-11-05
Recruiting
Bristol-Myers Squibb
Phase 2/3
500
Ravenna, Aviano, Orbassano, Candiolo, Avellino, Milan, Naples, Parma
2025-11-05
Recruiting
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
5
Milan
2025-11-04
Recruiting
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
NCT07085767Breast Cancer, Locally Advanced Breast Cancer, Metastatic Breast Cancer, ER Positive Breast Cancer
DrugsPalazestrant·Ribociclib·Letrozole
Olema Pharmaceuticals, Inc.
Phase 3
1,000
Naples, Bologna, Aviano, Rome, Genoa, Bergamo, Milan, Monza
2025-11-03
Recruiting
Observational Study for the Characterisation of Patients Affected by Any Type of Diabetes and Endocrine Disorders
NCT07206875Diabetes, Metabolic Disorders, Arterial Hypertension, Dyslipidemia
IRCCS San Raffaele
Observational
10,000
Milan
2025-11-03
Recruiting
MultidISciplinary Care paThway tailoRed on frAilty in Cancer Patients Referred to Outpatient paLliative Care
NCT07469761Palliative Care, Palliative Care, Health Services, Patient Reported Outcome (PRO), Patient Reported Outcome Measurements
Augusto Caraceni
Not applicable
120
Milan
2025-11-02
Recruiting
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Not applicable
100
Milan
2025-11-01
Recruiting
DEFINING THE GENETIC DRIVERS OF ADULT-ONSET CHOLESTATIC LIVER DISEASE
NCT07317193Cholestatic Liver Disease, Progressive Familial Intrahepatic Cholestasis
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
60
Milan
2025-11-01
Recruiting
Association Between EIT and CT During PEEP Titration in Patients With Acute Respiratory Failure
NCT07175194Acute Hypoxemic Respiratory Failure, Ventilation, Mechanical
Istituto Clinico Humanitas
Observational
30
Milan
2025-11-01
Recruiting
Philogen S.p.A.
Phase 1
56
Bergamo, Milan, Naples
2025-10-31
Recruiting
AstraZeneca
Phase 3
400
Milan, Monza, Orbassano, Padova, Rozzano
2025-10-31
Recruiting
Ciceri Fabio
Not applicable
62
Milan, Bari, Parma
2025-10-31
Recruiting
AstraZeneca
Phase 3
100
Aviano, Florence, Meldola, Milan, Naples, Roma
2025-10-30
Recruiting
GlaxoSmithKline
Phase 2
363
Milan, Naples, Roma
2025-10-30
Recruiting
BioNTech SE
Phase 3
558
Aviano, Lucca, Milan, Monza, Pisa, Roma, Siena, Torrette
2025-10-30
By invitation
Clinical Trial of Vormatrigine in Adult Patients With Epilepsy
NCT07287163Epilepsy, Tonic-Clonic, Focal Seizure, Primary Generalized Seizure
Praxis Precision Medicines
Phase 3
700
Pozzilli, Bosisio Parini, Milan, Naples, Pavia, Pisa, Ponderano, Roma
2025-10-27
Recruiting
Takeda
Phase 3
70
Messina, Milan, Pescara, Roma
2025-10-27
Recruiting
Sanofi
Phase 3
60
Meldola, Milan, Naples, Torino, Vicenza
2025-10-24
Recruiting
Daiichi Sankyo
Phase 3
686
Bologna, Candiolo, Fano, Genova, Livorno, Milan, Misterbianco, Orbassano
2025-10-24
Recruiting
Hoffmann-La Roche
Phase 3
600
Statte, Naples, Modena, Pesaro, Aviano, Rome, Genoa, Milan
2025-10-24
Active, closed
Bristol-Myers Squibb
Phase 2/3
470
Meldola, Rome, Milan, Rozzano, Pisa, Padova, Naples, Verona
2025-10-23
Recruiting
Eli Lilly and Company
Phase 3
1,630
Bologna, Catania, Lecce, Lucca, Milan, Modena, Naples, Prato
2025-10-22
Recruiting
Acesion Pharma
Phase 2
200
Bologna, Cona, Mestre, Milan, Modena
2025-10-22
Recruiting
Laboratorio Farmaceutico SIT srl
Phase 4
240
Alessandria, Catania, Milan, Roma, Sassari
2025-10-21
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with an Italian investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 12 November 2026. https://priyalifescience.com/clinical-trials-italy/city/milan

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Italy and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 6,779 studies in total at the last sync on 10 Nov 2026, 03:19 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 2,847 of those studies with a site in Milan.

How many clinical trials are recruiting in Milan?

1,602 of the 2,847 studies on this page are recruiting new participants as of the 10 Nov 2026, 03:19 UTC sync. A further 133 have not yet opened recruitment, 1,037 are active but closed to new participants, and 75 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Milan), 2,847 studies
PhaseStudiesRecruitingShare
Phase 388738631.2%
Observational82458328.9%
Phase 237818413.3%
Not applicable37423013.1%
Phase 1/21751036.1%
Phase 192433.2%
Phase 2/374462.6%
Phase 443271.5%

Most active sponsors

Lead sponsors with the most studies (Milan)
Lead sponsorStudiesRecruiting
IRCCS San Raffaele15695
AstraZeneca14061
Merck Sharp & Dohme LLC9853
Hoffmann-La Roche7728
Novartis Pharmaceuticals7426
European Institute of Oncology7357
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico6245
Janssen Research & Development, LLC6228
Eli Lilly and Company5228
AbbVie5015
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.