Study to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression
Condition(s) studied
Investigational drug(s) / intervention(s)
INCB123667: Oral; tablet
Investigator's choice of chemotherapy: The investigator will select the chemotherapy in accordance with the protocol-defined requirements. The possible choices as defined by the protocol:
Study summary
The purpose of this study is to evaluate INCB123667 versus investigator's choice of chemotherapy in participants with platinum-resistant ovarian cancer with cyclin E1 overexpression.
Eligibility
Primary outcome measure(s)
- Progression-Free Survival (PFS) by BICR — Up to 2 years
Defined as the time from the date of randomization until the earliest date of disease progression as determined by blinded independent central review (BICR) per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1, or death due to any cause, whichever occurs first. - Overall Survival (OS) — Up to 2 years
Defined as the time from the date of randomization until death due to any cause.
Trial sites (192)
| Facility | City | Region | Status |
|---|---|---|---|
| Alaska Womens Cancer Care Akwcc | Anchorage | Alaska | Not Yet Recruiting |
| University of Arizona Cancer Center | Tucson | Arizona | Not Yet Recruiting |
| City of Hope Medical Center | Duarte | California | Not Yet Recruiting |
| Providence Medical Foundation | Fullerton | California | Not Yet Recruiting |
| University of California, San Diego-Moores Cancer Center | La Jolla | California | Not Yet Recruiting |
| Valkyrie Clinical Trials | Los Angeles | California | Recruiting |
| Uci Health Chao Family Comprehensive Cancer Center | Orange | California | Not Yet Recruiting |
| Ventura County Hematology Oncology Specialists-Oxnard | Oxnard | California | Not Yet Recruiting |
| University of Colorado Cancer Center | Aurora | Colorado | Not Yet Recruiting |
| Brcr Global | Miramar | Florida | Not Yet Recruiting |
| Sarasota Memorial Health Care System | Sarasota | Florida | Not Yet Recruiting |
| Winship Cancer Institute At Emory University | Atlanta | Georgia | Not Yet Recruiting |
| Georgia Cancer Center | Augusta | Georgia | Not Yet Recruiting |
| The University of Chicago Medicine | Chicago | Illinois | Not Yet Recruiting |
| Carle Cancer Center | Effingham | Illinois | Not Yet Recruiting |
| Northshore University Health System-Evanston Hospital | Evanston | Illinois | Not Yet Recruiting |
| City of Hope - Chicago Cancer Center | Zion | Illinois | Not Yet Recruiting |
| St Elizabeth Healthcare | Edgewood | Kentucky | Not Yet Recruiting |
| Women'S Cancer Care | Covington | Louisiana | Not Yet Recruiting |
| Trials365, Llc | Shreveport | Louisiana | Not Yet Recruiting |
| Maine Center For Cancer Medicine | Scarborough | Maine | Not Yet Recruiting |
| Holy Cross Hospital | Silver Spring | Maryland | Not Yet Recruiting |
| Henry Ford Cancer - Detroit | Detroit | Michigan | Not Yet Recruiting |
| Mercy Hospital St. Louis - David C. Pratt Cancer Center | St Louis | Missouri | Not Yet Recruiting |
| Billings Clinic | Billings | Montana | Recruiting |
| Women'S Cancer Center of Nevada | Las Vegas | Nevada | Not Yet Recruiting |
| Center of Hope | Reno | Nevada | Not Yet Recruiting |
| Maimonides Medical Center | Short Hills | New Jersey | Not Yet Recruiting |
| Unm Comprehensive Cancer Center | Albuquerque | New Mexico | Not Yet Recruiting |
| Levine Cancer Center | Charlotte | North Carolina | Not Yet Recruiting |
| Novant Presbyterian Hospital | Charlotte | North Carolina | Recruiting |
| East Carolina University | Greenville | North Carolina | Not Yet Recruiting |
| Novant Health Oncology Specialists | Winston-Salem | North Carolina | Recruiting |
| Atrium Health Wake Forest Baptist | Winston-Salem | North Carolina | Not Yet Recruiting |
| Cleveland Clinic Foundation | Cleveland | Ohio | Not Yet Recruiting |
| Ohio Health Research Institute | Columbus | Ohio | Not Yet Recruiting |
| Miami Valley Hospital South | Dayton | Ohio | Not Yet Recruiting |
| Promedica Flower Hospital | Sylvania | Ohio | Not Yet Recruiting |
| Oncology Associates of Oregon, P.C. | Eugene | Oregon | Recruiting |
| Providence Cancer Institute Franz Clinic | Portland | Oregon | Not Yet Recruiting |
+ 152 more sites — see the full list on the official registry below.
More Incyte Corporation trials in Italy
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07214779 on ClinicalTrials.gov ↗ ← All trials in Italy