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Clinical Trials in Italy / NCT07617974
Recruiting Observational

Natural History of Atrial Fibrillation-Induced Tricuspid Valve Remodeling in the Absence of Significant Tricuspid Regurgitation: A Three-Dimensional Echocardiographic Study

NCT07617974 · tracked via the Priya Life Science Italy tracker
Phase
Observational
Started
2026-05-04
Last updated
2026-06-01

Condition(s) studied

Atrial Fibrillation (AF)Tricuspid Regurgitation (TR)

Study summary

This is a prospective, observational, multicenter study aimed at characterizing tricuspid valve remodeling in patients with atrial fibrillation (AF) without significant tricuspid regurgitation (TR), in relation to AF burden progression.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria: * Consecutive patients with atrial fibrillation (paroxysmal or persistent) undergoing transthoracic echocardiography (TTE) prior to AF ablation with acquisition of a 3D TV dataset. Eligible for enrollment in the control group will be: 1. all consecutive patients with structurally normal hearts and no history of AF or; 2. moderate atrial functional tricuspid regurgitation and AF, in the absence of significant left-sided valvular disease or prior valvular surgery. Exclusion Criteria: * Moderate or greater TR assessed using a multiparametric approach; * Arrhythmias other than AF; * Prior AF ablations; * Rapid ventricular response (average HR \>110 bpm) during baseline TTE; * Inadequate image quality

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Centro Cardiologico Monzino; IRCCS Milan Milan Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07617974 on ClinicalTrials.gov ↗ ← All trials in Italy