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Trackers› Clinical trials› Messina
Clinical trial register · Italy

Clinical Trials in Messina, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Italy and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 6778 matching records held by the registry are in this view. Synced 08 Oct 2026, 03:19 UTC
6778
Studies in scope
all four open statuses
4069
Recruiting now
open to new participants
1018
Lead sponsors
across recruiting studies
Top sites
Milan 2843 Bologna 1305 Roma 1274 Naples 984 Rome 967
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
IRCCS Centro Neurolesi Bonino Pulejo25 Istituto per la Ricerca e l'Innovazione Biomedica13 AstraZeneca8 AbbVie6 Takeda5
Site location
Milan2843 Bologna1305 Roma1274 Naples984 Rome967
All 489 locations
Target enrolment
to

Trials with a site in Messina

168 of 6778 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Italy
Start
Not yet open
Alexion Pharmaceuticals, Inc.
Phase 3
1,180
Bologna, Forlì, Florence, Rome, Messina, Naples, Padova, Pisa
2027-11-23
Not yet open
Chiesi Farmaceutici S.p.A.
Phase 3
700
Brescia, Brindisi, Genoa, Messina, Milan, Naples, Parma, Pisa
2026-11-16
Recruiting
A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency.
NCT07559175Exocrine Pancreatic Insufficiency (EPI), Cystic Fibrosis (CF), Pancreatic Enzyme Abnormality, Pancreatic Diseases
DrugZenpep
Aimmune Nestlé Health Science US R&D, LLC
Phase 2
66
Catania, Rozzano, Messina, Florence, Milan, Roma
2026-10
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
90
Ancona, Florence, Genova, Messina, Milan, Roma, Rome, Verona
2026-09-15
Not yet open
Non-Coding RNAs Gene Expression in Psychiatric Disorders
NCT07649993Schizophrenia Disorders, Major Depression, Bipolar Affective Disorders, Obsessive Compulsive Disorder (OCD)
Carmen Concerto
Observational
384
Catania, Enna, Messina, Palermo
2026-09-01
Not yet open
Cognitive Training in Virtual Reality for Autism
NCT07643649Autism, Autism Spectrum Disorder
Istituto per la Ricerca e l'Innovazione Biomedica
Not applicable
30
Messina
2026-09-01
Not yet open
Eli Lilly and Company
Phase 3
170
Ancona, Florence, Genova, Messina, Milan, Naples, Verona
2026-09
Recruiting
Real-World Effectiveness and Safety of Pegcetacoplan in Patients With C3G or IC-MPG: A Multi-Country Study
NCT07746895C3 Glomerulopathy (C3G), Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN)
DrugPegcetacoplan
Swedish Orphan Biovitrum
Phase 4
150
Bari, Bologna, Foggia, Messina, Milan, Roma, Udine
2026-08-05
Recruiting
Pharming Technologies B.V.
Phase 2
140
Messina, Milan, Pisa
2026-06-12
Recruiting
Novo Nordisk A/S
Phase 3
2,500
Bologna, Genoa, Brescia, Milan, Perugia, Messina, Ancorna, Pisa
2026-05-21
Active, closed
Burnout and Well-Being in Healthcare Workers Participating in Workplace Yoga
NCT07786584Burnout, Occupational Burnout, Yoga Therapy
IRCCS Centro Neurolesi Bonino Pulejo
Observational
70
Messina
2026-05-20
Recruiting
Digital Engagement for Lifelong Health
NCT07612852Life Style, Healthy, Risk Reduction, Health Promotion
Istituto per la Ricerca e l'Innovazione Biomedica
Not applicable
200
Messina
2026-05-04
Recruiting
Boehringer Ingelheim
Phase 2
132
Ancona, Bari, Bologna, Messina, Milan, Pavia, San Giovanni Rotondo (FG), Verona
2026-03-23
Recruiting
Eli Lilly and Company
Phase 4
150
Alessandria, Florence, Messina, Monza, Perugia, Rome, Terni
2026-03-09
Recruiting
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398Pulmonary Hypertension Associated With HFpEF
DrugTNX-103
Tenax Therapeutics, Inc.
Phase 3
540
Acquaviva delle Fonti, Bergamo, Messina, Milan, Pavia, Pisa, Roma, Rozzano
2026-03-03
Recruiting
Cognitive and Physical Recovery After Hip Fracture in Frail Patients Using Digital Rehabilitation Technology
NCT07392515Fracture Femur, Hip Arthroplasty Replacement, Total Hip Arthroplasty (THA)
C.O.T. Cure Ortopediche Traumatologiche S.p.A.
Not applicable
30
Messina, Roma
2026-02-09
Recruiting
Eli Lilly and Company
Phase 3
300
Ancona, Florence, Messina, Naples, Novara, Padova, Verona
2026-02-05
Recruiting
Istituto per la Ricerca e l'Innovazione Biomedica
Not applicable
30
Messina
2026-02-02
Recruiting
Liver and Coagulation Disorders in Cardiac Transthyretin Amyloidosis
NCT07766135Transthyretin (TTR) Amyloid Cardiomyopathy, Cardiac Amyloidosis, Cardiomyopathies, Wild-Type Transthyretin Cardiac Amyloidosis
University of Messina
Observational
70
Messina
2026-01-30
Recruiting
IRCCS Centro Neurolesi Bonino Pulejo
Observational
140
Messina
2026-01-16
Not yet open
Mild Cognitive Impairment and Psychopathology
NCT07358962Mild Cognitive Impairment (MCI)
IRCCS Centro Neurolesi Bonino Pulejo
Observational
118
Messina
2026-01-12
Recruiting
Static Balance Assessment in Children With ASD Using VRRS
NCT07403396Autism, Autism Spectrum Disorder
Istituto per la Ricerca e l'Innovazione Biomedica
Observational
50
Messina
2026-01-02
Recruiting
Myrosinase Bioactivated Gglucoraphanin for the Treatment of Neurodegenerative Diseases (GRA-MYR-ND)
NCT07360977PARKINSON DISEASE (Disorder), Multiple Sclerosis (MS) - Relapsing-remitting, Pediatric Patients Affected by Neuromuscolar and Degenerative Diseases
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
300
Messina
2026-01
Recruiting
Norgine
Phase 3
212
Bergamo, Florence, Messina, Milan, Naples, Roma
2025-12-29
Recruiting
Novo Nordisk A/S
Phase 3
332
Rome, Bergamo, Messina, Rivoli, Genova, Novara, Orbassano, San Donato Milanese
2025-12-18
Recruiting
Novartis Pharmaceuticals
Observational
250
Ancona, Bari, Brescia, Cona, Florence, Genova, Lecce, Messina
2025-12-17
Active, closed
Central Sensitisation in Nociceptive and Neuropathic Pain
NCT07321080Chronic Pain, Nociceptive Pain, Neuropathic Pain, Mixed Pain (Nociceptive and Neuropathic)
IRCCS Centro Neurolesi Bonino Pulejo
Observational
185
Messina
2025-12-15
Recruiting
IRCCS Centro Neurolesi Bonino Pulejo
Observational
151
Messina
2025-12
Recruiting
PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENSITIZATION IN HEADACHE
NCT07268768Chronic and Episodic Headache, Headache Disorders
IRCCS Centro Neurolesi Bonino Pulejo
Observational
64
Messina
2025-11-20
Recruiting
Shionogi
Phase 2
45
Messina, Torino
2025-10-30
Recruiting
Takeda
Phase 3
70
Messina, Milan, Pescara, Roma
2025-10-27
Recruiting
IRCCS Centro Neurolesi Bonino Pulejo
Observational
180
Messina
2025-10-27
Recruiting
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
60
Messina
2025-10-20
Recruiting
Alnylam Pharmaceuticals
Phase 3
11,000
Ancona, Cittadella, Lecco, L’Aquila, Messina, Milan, Naples, Novara
2025-09-22
Recruiting
Novo Nordisk A/S
Phase 4
586
Bari, Catanzaro, Naples, Rome, Milan, Messina, Palermo, Fermo
2025-08-15
Recruiting
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
108
Messina
2025-08-14
Recruiting
Sanofi
Phase 3
723
Florence, Genoa, Milan, Rome, Turin, Bologna, Messina, Novara
2025-08-06
Recruiting
Early Ravulizumab Treatment Of Anti- AChR Antibody-Positive Generalized Myasthenia Gravis
NCT06967480Generalized Myasthenia Gravis, Anti-AChR Antibody Positive
DrugRavulizumab
Alexion Pharmaceuticals, Inc.
Observational
40
Bergamo, Bologna, Brescia, Florence, Imperia, Lecco, Messina, Milan
2025-07-31
Recruiting
A Muscle-brain Interplay Study in Neurological Disorders
NCT07477821Neurological Disorders, Health Adult Subjects
Istituti Clinici Scientifici Maugeri SpA
Observational
150
Catania, Messina, Milan, Roma
2025-07-24
Recruiting
Takeda
Phase 3
347
Bologna, Brescia, Genoa, Messina, Milan, Pavia, Piacenza, Torino
2025-07-15
Recruiting
Repurposing Mirtazapine in Rett Syndrome
NCT07430046RETT Syndrome With Proven MECP2 Mutation
DrugMirtazapine
University of Trieste
Phase 2
54
Genova, Messina, Milan, Siena
2025-07-09
Active, closed
REal-life ON PARKinson's - ITaly (REONPARK-IT)
NCT07403799Parkinson Disease
Bial - Portela C S.A.
Observational
200
Bari, Brescia, Cagliari, Catanzaro, Chieti, Genova, Messina, Milan
2025-07-08
Not yet open
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Not applicable
150
Messina
2025-06-15
Recruiting
Boehringer Ingelheim
Phase 3
1,755
Ancona, Bologna, Catania, Genova, Messina, Milan, Monza (MB), Naples
2025-06-09
Recruiting
Bruno Bombaci
Observational
50
Messina
2025-06-01
Not yet open
F.I.R.M.O. - Fondazione Italiana Ricerca sulle Malattie dell'Osso - Ente del Terzo Settore
Observational
100
Bari, Bologna, Brescia, Cagliari, Ferrara, Florence, Genova, Messina
2025-06-01
Recruiting
Eikon Therapeutics
Phase 2/3
740
San Giovanni Rotondo, Alessandria, Messina, Milan, Modena, Padova, Trento, Genoa
2025-05-22
Recruiting
Fondazione Don Carlo Gnocchi ETS
Not applicable
160
Acerenza, Bari, Genova, Messina, Milan, Montescano, Pavia, Rome
2025-05-20
Recruiting
Takeda
Phase 3
59
Milan, Rozzano, Orbassano, Brescia, Genova, Messina, Pavia, Pisa
2025-05-06
Recruiting
Physica TT Tibial Plate Follow up Study
NCT06337123Knee Arthropathy
Limacorporate S.p.a
Observational
130
Forte dei Marmi, Messina, Perugia
2025-04-15
Recruiting
Istituto Nazionale di Ricovero e Cura per Anziani
Observational
400
Ancona, Fermo, Messina
2025-04-09
Recruiting
PSMA PET for Treatment Response evaLuation of systemIC Therapies in prostAte caNcer (PELICAN)
NCT07089550PSMA Positive Tumors or Tumor Tissues, Prostate Cancer Metastatic
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
1,300
Bologna, Cuneo, Genova, Messina
2025-04-02
By invitation
Psychopathology in Adolescence
NCT07259109Anxiety Disorders, Depressive Disorder, Obsessive-Compulsive Disorder, Mental Health
IRCCS Centro Neurolesi Bonino Pulejo
Observational
192
Messina
2025-04-01
Recruiting
The Impact of Sensory Integration on Attention in Autism
NCT06872229Autism, Autism Spectrum Disorder
Istituto per la Ricerca e l'Innovazione Biomedica
Observational
100
Messina
2025-03-01
Recruiting
University of Milano Bicocca
Phase 2
118
Avezzano, Florence, Messina, Monza, Roma, Udine
2025-03-01
Not yet open
New Technological Pathway for Gait Rehabilitation
NCT06859229Neurological Diseases or Conditions, Cardiovascular Diseases, Neuromuscular Disease
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
60
Messina
2025-03
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
200
Alessandria, Bari, Bologna, Florence, Genova, Messina, Milan, Modena
2025-02-26
Recruiting
Istituto Clinico Humanitas
Observational
300
Benevento, Bergamo, Brindisi, Brescia, Campobasso, Florence, Genova, Messina
2025-02-25
Active, closed
Epidyolex® in Lennox Gastaut, Dravet Syndrome and Tuberous Sclerosis Complex: an Observational Study in ITALY
NCT05485831Lennox Gastaut Syndrome, Dravet Syndrome, Tuberous Sclerosis Complex
DrugCannabidiol
Jazz Pharmaceuticals
Observational
111
Bologna, Catanzaro, Chieti, Florence, Genova, Messina, Milan, Naples
2025-02-24
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
60
Bologna, Bari, Cagliari, Catania, Catanzaro, Florence, Genova, Messina
2025-02-12
Recruiting
Cognitive Recovery Via Sensor-based Robotic Upper Limb Rehabilitation in Neurological Disorders
NCT07384143PARKINSON DISEASE (Disorder), Multiple Sclerosis, Stroke, Neurological Disorders
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
189
Messina
2025-02-11
By invitation
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
50
Messina
2025-02-01
Recruiting
Night-shift Work and Breast Cancer
NCT06786949Breast Cancer Risk Factors
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
6,000
Bologna, Messina
2025-01-31
Recruiting
AI and VR Devices for Eating Behavior Rehabilitation
NCT06799962Eating Disorders, Anorexia Nervosa, Bulimia Nervosa
Istituto per la Ricerca e l'Innovazione Biomedica
Not applicable
80
Messina
2025-01-30
Recruiting
Focused Ultrasound Unilateral Pallidotomy for Medication-Refractory Limb Dystonia
NCT07168850Limb Dystonia, Idiopathic Dystonia, Medication-refractory Dystonia, Dystonia, Focal
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Not applicable
34
Mestre, Messina, Milan, Palermo
2025-01-27
Recruiting
Takeda
Phase 3
70
Messina, Milan, Pescara, Rome
2025-01-22
Active, closed
Virtual Reality Rehabilitation for Cognitive, Emotional, and Motor Recovery in Neurological Disorders
NCT06838975Acquired Brain Injuries, Spinal Cord Injury, Multiple Sclerosis, Parkinson Disease
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
328
Messina
2025-01-16
By invitation
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
100
Messina
2025-01-10
Recruiting
Effectiveness of TeleVR App in Cognitive Decline and MCI Patients
NCT06793735Cognitive Dysfunction, Subjective Health, Mild Cognitive Impairment, Alzheimer Disease
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
480
Messina
2025-01-08
Recruiting
I.R.C.C.S. Fondazione Santa Lucia
Not applicable
60
Rome, Messina
2025-01-01
Active, closed
argenx
Phase 3
154
Florence, Genova, Gussago, Messina, Milan, Roma, Rozzano
2024-12-18
Recruiting
IRCCS Centro San Giovanni di Dio Fatebenefratelli
Not applicable
60
Brescia, Messina, Milan
2024-12-09
Recruiting
Takeda
Phase 3
30
Genova, Messina, Naples, Rome, Trieste
2024-11-19
Recruiting
F.I.R.M.O. - Fondazione Italiana Ricerca sulle Malattie dell'Osso - Ente del Terzo Settore
Observational
300
Bari, Bologna, Cagliari, Ferrara, Florence, Foggia, Genova, Messina
2024-11-04
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
200
Chieti, Milan, Messina, Roma
2024-11-01
Recruiting
COntact RElationship in Neonatal Intensive Care Unit
NCT06462638Preterm Birth, Postpartum Depression
Istituto per la Ricerca e l'Innovazione Biomedica
Observational
80
Messina
2024-11-01
Recruiting
Telehealth Intervention for Infants With Prodromes of ASD
NCT06817746Autism Spectrum Disorder (ASD)
IRCCS Fondazione Stella Maris
Not applicable
132
Pisa, Rovereto, Messina
2024-11-01
Recruiting
Fondazione Don Carlo Gnocchi ETS
Not applicable
126
Florence, Messina, Roma
2024-10-04
Recruiting
Istituto per la Ricerca e l'Innovazione Biomedica
Observational
30
Messina
2024-10-01
Recruiting
GlaxoSmithKline
Phase 2
393
Bergamo, Bologna, Messina, Milan, Padova, Roma
2024-09-27
Recruiting
Istituto Oncologico Veneto IRCCS
Phase 2
104
Meldola, Messina, Bagno a Ripoli, Aviano, Rozzano, Bari, Bologna, Florence
2024-09-23
Recruiting
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
NCT06528314NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis
DrugEfruxifermin
Akero Therapeutics, Inc
Phase 3
2,150
Foggia, San Giovanni Rotondo, Rozzano, Torino, Bologna, Catania, Messina, Milan
2024-09-04
Recruiting
Istituto per la Ricerca e l'Innovazione Biomedica
Not applicable
30
Messina
2024-09-01
Active, closed
University of Messina
Observational
100
Messina
2024-08-30
Recruiting
University of Cagliari
Observational
80
Cagliari, Novedrate, Troina, Messina, Palermo
2024-08-08
Recruiting
AbbVie
Phase 3
110
San Giovanni Rotondo, Rome, Messina, Milan
2024-08-08
Active, closed
A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work
NCT06290128Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Polyneuropathy, Inflammatory Demyelinating, Chronic
DrugRiliprubart
Sanofi
Phase 3
109
Milan, Rozzano, Rome, Messina, Palermo, Pavia, Pisa
2024-07-12
Recruiting
Cyber-Human Systems for Personalized Well-being and Health
NCT06490783Geriatric Health Services, Health Services for the Elderly
Istituto per la Ricerca e l'Innovazione Biomedica
Observational
10
Messina
2024-07-01
Recruiting
A Study to Describe the Diagnostic and Therapeutic Path of Patients with NSCLC in Early Stage and Locally Advanced
NCT06467383Non-small Cell Lung Cancer, NSCLC, NSCLC, Stage III, NSCLC, Stage I
MSD Italia S.r.l.
Observational
600
San Giovanni Rotondo, Brescia, Campobasso, Catania, Florence, Genova, Messina, Milan
2024-06-25
Recruiting
How Complexity and Multiple Illnesses Affect Hospitalized Patients' Health: a Multicenter Study
NCT06872632Complexity and Multiple Illnesses of Adult Hospitalized Internal Medicine Patient
Società Italiana di Medicina Interna
Observational
2,326
Bari, Bologna, Brescia, Ferrara, Florence, Messina, Milan, Modena
2024-06-24
Recruiting
H. Lundbeck A/S
Phase 2
18
Padova, Pisa, Messina, Rome, Torino
2024-06-19
Active, closed
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
NCT07066137Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
150
Messina
2024-05-05
By invitation
Visuospatial and Affective Abilities in Parkinson Disease
NCT06341829Parkinson Disease, Alexithymia, Visuospatial/Perceptual Abilities
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
126
Messina
2024-04-30
Recruiting
International Extranodal Lymphoma Study Group (IELSG)
Observational
300
Alessandria, Bari, Bergamo, Brescia, Catania, Cona, Florence, Messina
2024-04-11
Recruiting
Study of Olverembatinib (HQP1351) in Patients With CML-CP
NCT06423911Chronic Myeloid Leukemia, CML, CML, Chronic Phase
DrugsBosutinib·Olverembatinib
Ascentage Pharma Group Inc.
Phase 3
333
Bologna, Candiolo, Catania, Lecce, Meldola, Messina, Milan, Naples
2024-02-05
Active, closed
Astellas Gene Therapies
Not applicable
119
Florence, Gussago, Messina, Milan, Pavia, Pisa, Roma, Udine
2024-02-01
Recruiting
The DANCEREX Proof-of-Concept Study for Chronic Neurological Disorders
NCT06112639Sclerosis, Multiple, Neurocognitive Impairment, Mild, Neurocognitive Dysfunction
Fondazione Don Carlo Gnocchi ETS
Not applicable
192
Brescia, Messina, Milan
2024-01-31
Active, closed
Study of ALXN2220 Versus Placebo in Adults With ATTR-CM
NCT06183931Transthyretin Amyloid Cardiomyopathy
DrugCliramitug
Alexion Pharmaceuticals, Inc.
Phase 3
1,181
Bologna, Ferrara, Florence, Forlì, Messina, Milan, Naples, Padova
2024-01-11
Recruiting
Istituto per la Ricerca e l'Innovazione Biomedica
Observational
190
Messina
2024-01-10
Recruiting
Psychotropic-Drug-induced QT Prolongation and ECG Monitoring in the Pediatric Population
NCT06870006Eating Disorders, Mood Disorders in Children and Adolescents, Psychotic Disorder, QTc Intervals Changes
Meyer Children's Hospital IRCCS
Observational
100
Troina, Florence, Calambrone, Bologna, Cagliari, Messina
2024-01-01
Active, closed
Bioprojet
Phase 2
62
Bologna, Bosisio Parini, Cagliari, Calambrone, Foggia, Messina, Naples, Pavia
2023-12-20
Recruiting
AbbVie
Phase 3
110
Genoa, Naples, Rome, Messina
2023-12-11
Recruiting
Akero Therapeutics, Inc
Phase 3
1,650
San Giovanni Rotondo, Rozzano, Torino, Bologna, Foggia, Messina, Milan, Modena
2023-12-01
Active, closed
argenx
Observational
413
Florence, Gussago, Messina, Novara, Orbassano, Palermo, Pavia, Pisa
2023-11-29
Recruiting
Fondazione Don Carlo Gnocchi ETS
Not applicable
126
Florence, Messina, Roma
2023-11-13
Active, closed
Eli Lilly and Company
Phase 3
160
Bologna, Verona, Messina, Novara
2023-10-16
Recruiting
SILibinin in NSCLC and BC Patients With Single Brain METastasis (SILMET)
NCT05689619Brain Metastases, Adult, Non Small Cell Lung Cancer, Breast Cancer
A.O.U. Città della Salute e della Scienza
Not applicable
70
Genova, Messina, Rome, Turin
2023-09-01
Recruiting
AstraZeneca
Observational
52,121
Lecce, Messina, Milan
2023-08-21
Recruiting
Glaukos Corporation
Phase 2
84
Messina
2023-08-17
Active, closed
Integrated Management of Atypical Parkinsonism: A Home-based Patient-Centered Healthcare Delivery Based on Telenursing (IMPACT Study)
NCT05792332Atypical Parkinsonism, MSA - Multiple System Atrophy, PSP, Nurse-Patient Relations
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Not applicable
164
Messina, Milan, Pavia, Pozzilli
2023-08-17
Recruiting
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
200
Messina
2023-08-16
Active, closed
Mineralys Therapeutics Inc.
Phase 3
1,076
Bologna, Ferrara, Genova, Messina, Pisa, Roma
2023-07-14
Active, closed
AbbVie
Observational
1,019
Florence, Rozzano, Milan, Rome, Bari, Bologna, Messina
2023-06-09
Recruiting
Emotional Skills Training with Social Robot
NCT06179953Autism Spectrum Disorder
Istituto per la Ricerca e l'Innovazione Biomedica
Not applicable
20
Messina
2023-06-05
By invitation
Virtual Reality-assisted Cognitive Rehabilitation in Autistic Youth With ADHD
NCT07426302ADHD - Attention Deficit Disorder With Hyperactivity, Autism Spectrum Disorder
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
50
Messina
2023-06-01
Active, closed
Toward Molecular Profiling of Parkinson's Disease in Easily Accessible Biological Matrices
NCT07480187Parkinson Disease, Synucleinopathy, Alzheimer Disease
Azienda Ospedaliera di Perugia
Not applicable
340
Messina, Milan, Perugia
2023-05-20
Active, closed
Advancing Early Bone Health: New Frontiers for Osteoporosis Prevention
NCT06750523Low-Risk Pregnant Women at Full-Term Gestation, Healthy Fetal Population, Healthy Neonatal Population
University of Parma
Not applicable
200
Messina, Parma
2023-05-17
Active, closed
Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab
NCT05626855Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3, Spinal Muscular Atrophy Type 2, SMA
DrugApitegromab
Scholar Rock, Inc.
Phase 3
238
Genova, Messina, Milan, Roma
2023-04-17
By invitation
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
100
Messina
2023-02-01
Recruiting
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
100
Messina
2023-01-10
By invitation
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
100
Messina
2023-01-02
Active, closed
AstraZeneca
Phase 3
1,350
Florence, Lecco, Messina, Naples, Orbassano, Padova, Parma, Peschiera del Garda
2022-12-29
Recruiting
Pharming Technologies B.V.
Phase 2
180
Bologna, Messina, Milan, Pisa, Roma
2022-12-13
Recruiting
Quality Of Life On Elderly Patients With Low Grade Non-Hodgkin Lymphoma
NCT05524298Low Grade Non-Hodgkin's Lymphoma, Adult
Fondazione Italiana Linfomi - ETS
Observational
150
Alessandria, Ancona, Bari, Brescia, Castelfranco Veneto, Catania, Florence, Messina
2022-12-07
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
500
Genova, Messina, Milan, Rome
2022-11-28
Active, closed
AstraZeneca
Phase 3
1,174
Bologna, Brescia, Florence, Genova, Livorno, Meldola, Messina, Milan
2022-11-28
Active, closed
Vertex Pharmaceuticals Incorporated
Phase 3
297
Ancona, Florence, Genova, Messina, Milan, Naples, Orbassano, Potenza
2022-11-23
Active, closed
Janssen Research & Development, LLC
Phase 2
577
Bari, Catania, Messina, Milan, Monserrato, Monza, Negrar, Palermo
2022-09-19
Recruiting
Stemline Therapeutics, Inc.
Phase 1/2
73
Ancona, Candiolo, Meldola, Messina, Milan, Modena, Monza, Naples
2022-08-31
Active, closed
Janssen Research & Development, LLC
Phase 2
703
Bari, Catania, Messina, Milan, Monopoli, Monserrato, Monza, Negrar ( Ve)
2022-07-22
Active, closed
AstraZeneca
Phase 3
53
Messina, Naples, Roma
2022-07-01
Recruiting
A Multicenter Study for Evaluating a Digital Support System in Childhood Obesity Treatment
NCT04917601Childhood Obesity, Adolescent Obesity, mHealth, Personalized Medicine
Karolinska Institutet
Not applicable
680
Messina, Naples
2022-05-24
Recruiting
AbbVie
Phase 3
768
Misterbianco, Milan, Naples, Rome, Bari, Cremona, Messina, Perugia
2022-03-25
Active, closed
Otsuka Pharmaceutical Development & Commercialization, Inc.
Phase 3
530
Bologna, Brescia, Florence, Genova, Messina, Milan, Naples, Pavia
2022-03-15
Recruiting
Eye-tracking Technology for Severe Communication Disability
NCT05808478Communication Disabilities
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
30
Messina
2022-01-22
Active, closed
Microvention-Terumo, Inc.
Observational
206
Catania, Messina, Salerno
2022-01-14
Recruiting
Azienda Ospedaliero-Universitaria Careggi
Observational
10,000
Bari, Bologna, Florence, Foggia, Genova, Messina, Milan, Naples
2022-01-10
Active, closed
ITM Solucin GmbH
Phase 3
259
Messina, Milan, Rome
2021-12-21
Active, closed
Novartis Pharmaceuticals
Phase 3
1,007
Brindisi, Foggia, Pozzilli, Messina, Modena, Pavia, Orbassano, Naples
2021-12-13
Active, closed
AbbVie
Observational
873
Bari, Catania, Genoa, Messina, Milan, Turin, Roma, Cava de' Tirreni
2021-11-17
Recruiting
Istituto per la Ricerca e l'Innovazione Biomedica
Not applicable
33
Messina
2021-11-01
Recruiting
Study on the Diagnosis and Management of CLL in Italy by GIMEMA
NCT04867915Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, MBL-CLL - Monoclonal B-Cell Lymphocytosis Chronic Lymphocytic Leukaemia-Type
Gruppo Italiano Malattie EMatologiche dell'Adulto
Observational
12,500
Alessandria, Brescia, Brindisi, Candiolo, Florence, Messina, Mestre, Milan
2021-10-13
Active, closed
Fondazione Ricerca Traslazionale
Phase 2
105
Meldola, Saronno, Legnago, Negrar, Civitavecchia, Florence, Messina, Novara
2021-10-12
Active, closed
A Non-interventional Cohort Safety Study of Patients With hATTR-PN
NCT04850105Hereditary Transthyretin Amyloidosis With Polyneuropthy
Akcea Therapeutics
Observational
202
Roma, Bologna, Genova, Messina, Milan, Naples, Pavia
2021-09-21
Active, closed
AstraZeneca
Phase 3
98
Florence, Meldola, Messina, Naples, Padova, Roma, Terni, Verona
2021-09-12
By invitation
Viatris Innovation GmbH
Phase 3
25,000
Arezzo, Bologna, Caserta, Catania, Catanzaro, Cona, Florence, Messina
2021-08-14
Active, closed
The Medacta Quadra-P Anteverted Study
NCT05460715Arthrosis, Traumatic Arthritis, Rheumatoid Polyarthritis, Congenital Hip Dysplasia
Medacta International SA
Observational
300
Messina
2021-07-30
Active, closed
IRCCS San Raffaele Roma
Not applicable
70
Bologna, Ferrara, Foggia, Messina, Roma, Rome, San Giovanni Rotondo
2020-12-28
Active, closed
Neurocrine Biosciences
Phase 3
182
Ancona, Bologna, Florence, Messina, Milan, Naples, Padova, Roma
2020-12-16
Active, closed
Medstar Health Research Institute
Not applicable
3,100
Florence, Messina
2020-10-14
Active, closed
A Gene Transfer Study for Late-Onset Pompe Disease (RESOLUTE)
NCT04093349Pompe Disease, Pompe Disease (Late-onset), Glycogen Storage Disease Type 2, Glycogen Storage Disease Type II
Spark Therapeutics, Inc.
Phase 1/2
4
Messina, Milan, Naples, Pisa, Torino
2020-10-01
Active, closed
argenx
Phase 2
229
Brescia, Florence, Genova, Messina, Milan, Pisa, Roma, Torino
2020-09-18
Active, closed
AstraZeneca
Phase 3
866
Aviano, Bergamo, Candiolo, Cona, Genova, Livorno, Messina, Milan
2020-07-24
Recruiting
International CIPN Assessment and Validation Study
NCT04633655Chemotherapy-induced Peripheral Neuropathy, Quality of Life
University of Milano Bicocca
Observational
1,000
Monza, Como, Genova, Messina, Padova, Verona
2020-06-08
Active, closed
AstraZeneca
Phase 2
240
Bologna, Catanzaro, Meldola, Messina, Milan, Monza, Naples, Roma
2020-04-22
Recruiting
Centro di Riferimento Oncologico - Aviano
Observational
78
Aviano, Genova, Messina, Milan, Modena, Naples, Reggio Emilia, Roma
2019-08-27
Active, closed
Madrigal Pharmaceuticals, Inc.
Phase 3
1,759
Messina, Milan, Novara, Palermo, Roma, Bergamo, Florence, Pisa
2019-03-28
Active, closed
The European Robotic Spinal Instrumentation (EUROSPIN) Study
NCT03398915Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis, Recurrent Disc Herniation
Marc Schröder
Observational
932
Cesena, Ferrara, Messina, Roma
2019-01-01
Active, closed
Janssen Research & Development, LLC
Phase 3
84
Bologna, Florence, Messina, Roma, San Giovanni Rotondo, Trieste
2018-10-29
Recruiting
Natural History of SMA
NCT05755451Muscular Atrophy, Spinal
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,200
Genova, Messina, Milan, Rome
2018-06-21
Active, closed
Bristol-Myers Squibb
Phase 3
545
Messina, Bologna, Florence, Meldola, Milan, Modena, Monserrato, Naples
2018-04-18
Active, closed
Janssen Research & Development, LLC
Phase 2/3
1,409
Bologna, Cagliari, Cento, Messina, Milan, Padova, Roma, Rome
2018-04-13
Active, closed
AstraZeneca
Phase 2
273
Ancona, Bologna, Brescia, Cona, Genova, Lecco, Meldola, Messina
2018-03-07
Recruiting
Italfarmaco
Phase 2/3
206
Genova, Messina, Milan, Roma
2017-10-24
Active, closed
AbbVie
Observational
1,446
Milan, Rome, Bologna, Messina, Naples, Palermo, Parma, Pescara
2014-08-28
Active, closed
Bristol-Myers Squibb
Observational
2,555
Pesaro, Ancona, Cagliari, Florence, Lecce, Messina, Milan, Naples
2012-06-13
Recruiting
Global Registry and Natural History Study for Mitochondrial Disorders
NCT05554835Mitochondrial Diseases, Kearns-Sayre Syndrome, MIDD, SANDO
LMU Klinikum
Observational
6,000
Bologna, Brescia, Cagliari, Florence, Genova, Messina, Milan, Pisa
2009-02-01
Recruiting
Pompe Pregnancy Sub-Registry
NCT00567073Glycogen Storage Disease Type II (GSD-II), Pompe Disease (Late-onset), Glycogenesis 2 Acid Maltase Deficiency
Genzyme, a Sanofi Company
Observational
20
Florence, Milan, Padua, Rome, Brescia, Cagliari, Genova, Messina
2007-06-18
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with an Italian investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 10 October 2026. https://priyalifescience.com/clinical-trials-italy/city/messina

Query this register directly
GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Italy and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 6,778 studies in total at the last sync on 08 Oct 2026, 03:19 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 168 of those studies with a site in Messina.

How many clinical trials are recruiting in Messina?

99 of the 168 studies on this page are recruiting new participants as of the 08 Oct 2026, 03:19 UTC sync. A further 11 have not yet opened recruitment, 50 are active but closed to new participants, and 8 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Messina), 168 studies
PhaseStudiesRecruitingShare
Observational583834.5%
Not applicable422525%
Phase 3421925%
Phase 2181110.7%
Phase 2/3321.8%
Phase 4331.8%
Phase 1/2211.2%

Most active sponsors

Lead sponsors with the most studies (Messina)
Lead sponsorStudiesRecruiting
IRCCS Centro Neurolesi Bonino Pulejo2512
Istituto per la Ricerca e l'Innovazione Biomedica1312
AstraZeneca81
AbbVie63
Takeda55
Eli Lilly and Company42
Fondazione Don Carlo Gnocchi ETS44
Fondazione Policlinico Universitario Agostino Gemelli IRCCS42
IRCCS Azienda Ospedaliero-Universitaria di Bologna44
Janssen Research & Development, LLC40
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.