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Trackers› Clinical trials› North Carolina
Clinical trial register · United States · industry-sponsored

Clinical Trials in North Carolina, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9132 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 11 Oct 2026, 03:16 UTC
9132
Studies in scope
industry-sponsored, all four open statuses
4964
Recruiting now
open to new participants
2194
Lead sponsors
across recruiting studies
Top states
California 5299 Florida 4438 Illinois 2485 Georgia 2364 Arizona 2242
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AbbVie35 AstraZeneca32 Novartis Pharmaceuticals23 Janssen Research & Development, LLC22 Hoffmann-La Roche18
State
California5299 Florida4438 Illinois2485 Georgia2364 Arizona2242
All 51 states
Target enrolment
to

Trials with a site in North Carolina

1082 of 9132 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Active, closed
DexCom, Inc.
Not applicable
283
Colorado, Florida, Georgia, Indiana, Minnesota, Missouri, New York, North Carolina
2024-08-15
Recruiting
Intra-Cellular Therapies, Inc.
Phase 2
370
California, Florida, Georgia, New Jersey, North Carolina, Texas, Washington
2024-08-15
Recruiting
AquaPass Medical Ltd.
Not applicable
40
California, Minnesota, New York, North Carolina, Texas
2024-08-12
By invitation
Kerecis Real-World Fish Skin Graft Registry
NCT06384183Wounds, Pressure Ulcer, Diabetic Foot Ulcer, Venous Leg Ulcer
Kerecis Ltd.
Observational
600
Florida, North Carolina, Ohio, Texas
2024-08-07
Recruiting
Convergent Therapeutics
Phase 2
93
California, Massachusetts, Missouri, Nebraska, New York, North Carolina, Ohio
2024-08-06
Recruiting
Vivacelle Bio
Phase 3
46
Arizona, Georgia, Missouri, Nebraska, North Carolina, Oregon
2024-08-06
Recruiting
Study of XB010 in Subjects With Solid Tumors
NCT06545331Locally Advanced or Metastatic Solid Tumors, Esophageal Squamous Cell Cancer, Head and Neck Squamous Cell Cancer, NSCLC (Non-small Cell Lung Cancer)
DrugPembrolizumab
Exelixis
Phase 1
396
California, District of Columbia, Florida, Georgia, Illinois, Missouri, New York, North Carolina
2024-08-06
By invitation
Long-term Follow-up of Gene Therapy for Radiation-Induced Xerostomia
NCT06544798Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands
MeiraGTx, LLC
Phase 2
276
Arizona, Florida, Iowa, Missouri, New York, North Carolina, Pennsylvania
2024-08-02
Recruiting
VTP-1000 in Adults With Celiac Disease
NCT06310291Celiac Disease
Barinthus Biotherapeutics
Early Phase 1
45
California, Colorado, Florida, Maryland, Michigan, Minnesota, New York, North Carolina
2024-08-01
Active, closed
Bausch & Lomb Incorporated
Phase 4
216
California, Florida, Georgia, Indiana, Missouri, North Carolina, Tennessee
2024-07-31
Active, closed
Novartis Pharmaceuticals
Phase 3
146
Arizona, California, Georgia, Illinois, Maryland, Massachusetts, Michigan, North Carolina
2024-07-31
Recruiting
BRIM Biotechnology Inc.
Phase 2
12
North Carolina
2024-07-31
Active, closed
Palvella Therapeutics, Inc.
Phase 3
51
California, Georgia, Minnesota, New York, North Carolina, Ohio, Pennsylvania, Tennessee
2024-07-31
Active, closed
Belite Bio, Inc
Phase 2/3
60
Arizona, California, Florida, Massachusetts, Minnesota, New York, North Carolina, Pennsylvania
2024-07-31
Recruiting
Basking Biosciences, Inc.
Phase 2
228
Arizona, California, Florida, Michigan, Missouri, New Jersey, North Carolina, Ohio
2024-07-31
Active, closed
AbbVie
Phase 2
108
California, Kentucky, Maryland, Missouri, Nevada, New Jersey, New York, North Carolina
2024-07-29
Active, closed
Avidity Biosciences, Inc.
Phase 2
84
California, Colorado, Florida, Georgia, Kansas, New York, North Carolina, Ohio
2024-07-25
Active, closed
Ferrer Internacional S.A.
Phase 2
241
California, Colorado, Florida, Georgia, Massachusetts, Michigan, New York, North Carolina
2024-07-23
Recruiting
Teva Branded Pharmaceutical Products R&D LLC
Phase 1
240
California, Florida, Illinois, Michigan, North Carolina, Ohio, Pennsylvania, Tennessee
2024-07-22
Recruiting
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
Phase 2
385
California, Colorado, Florida, Georgia, Louisiana, Missouri, Nevada, North Carolina
2024-07-18
Active, closed
Zydus Therapeutics Inc.
Phase 3
102
California, Colorado, Connecticut, Florida, Georgia, Indiana, New York, North Carolina
2024-07-16
Active, closed
Merck Sharp & Dohme LLC
Phase 3
300
Arizona, California, Colorado, Connecticut, Indiana, Michigan, Nevada, North Carolina
2024-07-16
Active, closed
UCB Biopharma SRL
Phase 3
70
Alabama, New Jersey, North Carolina
2024-07-10
Recruiting
A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors
NCT06515613Platinum-resistant Ovarian Cancer, Testicular Cancer, Endometrial Cancer
Context Therapeutics Inc.
Phase 1
156
Arkansas, California, Colorado, Massachusetts, Nebraska, New Jersey, New York, North Carolina
2024-07-10
Recruiting
AbbVie
Phase 3
40
Arkansas, District of Columbia, Florida, Indiana, Minnesota, New York, North Carolina, Ohio
2024-07-08
Active, closed
Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia
NCT06449378Hernia, Hernia, Ventral, Hernia, Abdominal, Hernia Abdominal Wall
Medtronic - MITG
Not applicable
163
Illinois, Kentucky, North Carolina, Ohio, Virginia
2024-07-02
Recruiting
Cabaletta Bio
Phase 2/3
37
Connecticut, Florida, Illinois, Kansas, Michigan, Minnesota, New York, North Carolina
2024-07-02
Active, closed
Sun Pharmaceutical Industries Limited
Phase 4
10
North Carolina
2024-07-01
Recruiting
Intensity Therapeutics, Inc.
Phase 3
333
California, Connecticut, Michigan, Nebraska, North Carolina, Ohio, Pennsylvania
2024-06-28
Recruiting
argenx
Phase 2/3
12
North Carolina, Texas, Virginia
2024-06-28
Active, closed
Pfizer
Phase 1
64
Arkansas, California, Colorado, District of Columbia, Michigan, Missouri, North Carolina, Ohio
2024-06-27
Recruiting
BiVACOR® Total Artificial Heart Early Feasibility Study
NCT06174103Heart Failure, Biventricular Failure
BiVACOR Inc.
Not applicable
20
Arizona, North Carolina, Ohio, Texas
2024-06-26
Recruiting
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Phase 3
264
Arizona, Colorado, Connecticut, District of Columbia, Florida, Kansas, North Carolina, Ohio
2024-06-25
Recruiting
A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
NCT07491172Cardiovascular, Metabolic Disease, Dyslipidemias, Lipid Disorder
CRISPR Therapeutics AG
Phase 1
90
Florida, New York, North Carolina, Oregon
2024-06-21
Recruiting
SterileCare Inc.
Not applicable
124
Massachusetts, Nebraska, New York, North Carolina, Ohio, Texas, Washington
2024-06-21
Recruiting
Schrödinger, Inc.
Phase 1
52
Connecticut, Illinois, Michigan, New York, North Carolina, Ohio, Oklahoma, Tennessee
2024-06-18
By invitation
A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301
NCT06363760Sickle Cell Disease, Transfusion-dependent Beta-Thalassemia, Hemoglobinopathies
Editas Medicine, Inc.
Observational
54
California, Colorado, Connecticut, Florida, Georgia, Minnesota, New York, North Carolina
2024-06-17
Active, closed
AbbVie
Phase 1
60
Arizona, Florida, Michigan, Minnesota, North Carolina, Wisconsin
2024-06-17
Active, closed
Natera, Inc.
Not applicable
250
California, Colorado, Florida, Kansas, Massachusetts, Michigan, New York, North Carolina
2024-06-10
Recruiting
Kuros Biosurgery AG
Not applicable
100
Connecticut, Illinois, Maryland, Michigan, North Carolina, Ohio, Utah, Virginia
2024-06-10
Active, closed
SHINKEI Therapeutics, Inc
Phase 2
45
California, Florida, Maine, Michigan, Missouri, New Jersey, New Mexico, North Carolina
2024-06-01
Recruiting
TG Therapeutics, Inc.
Observational
728
North Carolina
2024-06-01
Active, closed
QTX3046 in Patients With KRAS G12D Mutations
NCT06428500Advanced Solid Tumor
Quanta Therapeutics
Phase 1
240
Michigan, North Carolina, Texas, Utah
2024-05-30
Recruiting
Lomond Therapeutics Holdings, Inc.
Phase 1
150
California, Georgia, Illinois, Kansas, Maryland, New York, North Carolina, Ohio
2024-05-29
Recruiting
Jiangsu Simcere Pharmaceutical Co., Ltd.
Phase 1
130
Arizona, California, Florida, Massachusetts, Minnesota, New York, North Carolina, Tennessee
2024-05-24
Recruiting
A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)
NCT06351631Thrombocythemia, Essential, Primary Myelofibrosis, Myelofibrosis, Post-polycythemia Vera Myelofibrosis
DrugBomedemstat
Merck Sharp & Dohme LLC
Phase 3
400
Michigan, North Carolina, Ohio, Pennsylvania
2024-05-23
Recruiting
NMD Pharma A/S
Phase 2
84
California, Colorado, Florida, Georgia, Missouri, North Carolina, Ohio, Oregon
2024-05-16
Recruiting
Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU
NCT06116110Non Hodgkin Lymphoma, Refractory Diffuse Large B Cell Lymphoma (DLBCL), Relapsed Diffuse Large B Cell Lymphoma, High Grade B-cell Lymphoma
Miltenyi Biomedicine GmbH
Observational
150
Arizona, California, Connecticut, Illinois, Kansas, Maryland, Massachusetts, North Carolina
2024-05-15
Active, closed
Alexion Pharmaceuticals, Inc.
Phase 3
30
Maryland, Missouri, North Carolina
2024-05-14
Recruiting
Encoded Therapeutics
Phase 1/2
47
California, Colorado, Florida, Illinois, Massachusetts, Michigan, Minnesota, North Carolina
2024-05-14
Active, closed
The ACES Study for Aseptic Pleural Effusion
NCT06210685Pleural Effusion
Pleural Dynamics, Inc.
Not applicable
25
Florida, Maryland, North Carolina, Tennessee
2024-05-12
Recruiting
Equilibra Bioscience LLC
Phase 1
31
California, Illinois, Louisiana, Michigan, Missouri, North Carolina, Pennsylvania
2024-05-10
Active, closed
AstraZeneca
Phase 4
1,511
California, Kentucky, Massachusetts, Michigan, Minnesota, North Carolina, Pennsylvania, Texas
2024-05-10
Active, closed
Lirio
Observational
12,000
North Carolina
2024-05-01
Recruiting
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
NCT06164730Heterozygous Familial Hypercholesterolemia, Premature Coronary Heart Disease
DrugVERVE-102
Verve Therapeutics, Inc.
Phase 1
85
Alabama, California, Florida, Indiana, North Carolina, Pennsylvania, Texas, Washington
2024-04-30
By invitation
Travere Therapeutics, Inc.
Phase 3
100
Arizona, Connecticut, Georgia, Illinois, Maine, Maryland, New York, North Carolina
2024-04-30
Recruiting
Century Therapeutics, Inc.
Observational
375
Arizona, California, Maryland, Michigan, North Carolina, Ohio, Washington
2024-04-29
Recruiting
Karyopharm Therapeutics Inc
Phase 2
58
California, Maryland, New York, North Carolina, Ohio, Texas, Utah
2024-04-22
Active, closed
34 Lives, PBC
Observational
80
Illinois, Indiana, Missouri, New York, North Carolina, Wisconsin
2024-04-19
Active, closed
P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies
NCT06014762Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, High-grade B-cell Lymphoma, Primary Mediastinal Large B-cell Lymphoma (PMBCL), Transformed Follicular Lymphoma (tFL)
DrugRimiducid
Poseida Therapeutics, Inc.
Phase 1
120
California, Florida, Indiana, Louisiana, Michigan, New York, North Carolina, Ohio
2024-04-16
Active, closed
argenx
Phase 3
119
Arizona, California, Florida, Georgia, Kansas, New Jersey, North Carolina, Ohio
2024-04-16
Active, closed
Edgewise Therapeutics, Inc.
Phase 2
79
California, Georgia, Massachusetts, Michigan, Missouri, New Jersey, New York, North Carolina
2024-04-11
Active, closed
Merck Sharp & Dohme LLC
Phase 2
272
California, Connecticut, Massachusetts, New York, North Carolina, Pennsylvania, Texas
2024-04-10
Active, closed
Medtronic - MITG
Not applicable
206
Florida, Illinois, New York, North Carolina, Ohio, Texas, Virginia
2024-04-08
Recruiting
Project Mountain - Comparing SpO2 and SaO2 for Accuracy
NCT06372106SpO2, Nasal Alar Collapse, Bilateral, Oxygen, Measurement
Philips Clinical & Medical Affairs Global
Observational
560
Arizona, Nebraska, North Carolina, South Carolina, Texas
2024-04-04
Active, closed
Artiva Biotherapeutics, Inc.
Phase 1
51
Alabama, Arizona, California, Florida, Iowa, North Carolina, Texas
2024-04-03
Recruiting
CytomX Therapeutics
Phase 1
160
Colorado, Massachusetts, New York, North Carolina, Tennessee, Texas, Virginia
2024-04-02
Active, closed
Alexion Pharmaceuticals, Inc.
Phase 3
43
Connecticut, Maryland, Minnesota, Missouri, North Carolina, Tennessee
2024-04-02
Recruiting
AbbVie
Phase 1/2
76
Florida, Massachusetts, Minnesota, New York, North Carolina, Oregon, Tennessee, Washington
2024-04-01
Recruiting
Pacira Pharmaceuticals, Inc
Phase 1
48
Indiana, Missouri, North Carolina, Oklahoma, Texas
2024-03-29
Active, closed
Merck Sharp & Dohme LLC
Phase 1/2
230
California, Florida, Illinois, Iowa, New York, North Carolina, Ohio, Pennsylvania
2024-03-28
Recruiting
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
NCT06308978Antineutrophilic Cytoplasmic Antibody (ANCA)- Associated Vasculitis (AAV), Idiopathic Inflammatory Myositis (IIM), Systemic Sclerosis (SSc), Systemic Lupus Erythematosus (SLE)
DrugsFT819·Fludara·Bendamustine·Cytoxan
Fate Therapeutics
Phase 1
244
California, Florida, Kentucky, Minnesota, Nebraska, New York, North Carolina, Ohio
2024-03-28
Active, closed
HeartFlow, Inc.
Observational
20,000
North Carolina
2024-03-27
Recruiting
Italfarmaco
Phase 3
220
Alabama, California, Colorado, Maryland, New York, North Carolina, Ohio, Oregon
2024-03-26
Recruiting
Terns, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Phase 1/2
180
Alabama, Arizona, California, Colorado, Florida, Georgia, New York, North Carolina
2024-03-26
Active, closed
TG Therapeutics, Inc.
Observational
16
California, Georgia, Massachusetts, North Carolina, Tennessee
2024-03-26
Active, closed
Edgewise Therapeutics, Inc.
Phase 2
43
California, Florida, Massachusetts, Missouri, North Carolina, Ohio
2024-03-22
Active, closed
Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid Tumors
NCT06334432Advanced Solid Tumor, HER2-negative Breast Cancer, Metastatic Castration-resistant Prostate Cancer (mCRPC), Pancreatic Cancer
Nuvation Bio Inc.
Phase 1/2
466
Michigan, New Jersey, New York, North Carolina, Texas, Utah, Virginia, Washington
2024-03-14
Recruiting
Organ Retractor Device Study
NCT06754514Liver Retraction During Bariatric Surgery
Boehringer Labs LLC
Observational
150
North Carolina
2024-03-14
Active, closed
Beacon Therapeutics
Phase 2/3
85
Arizona, California, Florida, Indiana, Maryland, Massachusetts, Minnesota, North Carolina
2024-03-14
Active, closed
AbbVie
Phase 1
152
California, Connecticut, Florida, Illinois, Michigan, North Carolina, Rhode Island, Texas
2024-03-08
Active, closed
Xentria, Inc.
Phase 2
31
Colorado, Illinois, North Carolina, Ohio, Pennsylvania
2024-03-01
Active, closed
VIA Disc NP Registry 3.0
NCT06345690Discogenic Pain, Back Pain, Back Pain, Low
VIVEX Biologics, Inc.
Observational
500
Arkansas, Colorado, Florida, Georgia, Indiana, Louisiana, North Carolina, Oklahoma
2024-02-27
Active, closed
Daiichi Sankyo
Phase 1
210
California, Florida, Hawaii, Illinois, Massachusetts, New York, North Carolina, Ohio
2024-02-22
Active, closed
Persona IQ Cohort Study
NCT06089291Osteo Arthritis Knee, Knee Arthritis, Monitoring Orthopedic Devices, Total Knee Arthroplasty
Zimmer Biomet
Observational
200
Indiana, Missouri, North Carolina, Pennsylvania
2024-02-20
Active, closed
Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)
NCT06117774Limited Stage Small Cell Lung Cancer, Small Cell Lung Cancer
DrugTarlatamab
Amgen
Phase 3
404
California, Connecticut, Florida, Kentucky, Louisiana, New Jersey, New York, North Carolina
2024-02-20
By invitation
Gradient Denervation Technologies
Not applicable
50
Illinois, Massachusetts, North Carolina, South Carolina, Texas, Wisconsin
2024-02-20
Active, closed
Vertex Pharmaceuticals Incorporated
Phase 1/2
47
California, Florida, Kansas, Massachusetts, Missouri, North Carolina, Pennsylvania, Virginia
2024-02-20
By invitation
An Observational Study of Patients With Chronic Liver Disease
NCT05744713Chronic Liver Disease, Cirrhosis
Target PharmaSolutions, Inc.
Observational
500,000
California, District of Columbia, Illinois, New York, North Carolina, Pennsylvania, Texas
2024-02-19
Recruiting
Oral Pyridoxal 5'-Phosphate for the Treatment of Patients With PNPO Deficiency
NCT04706013Pyridox(am)Ine 5'-Phosphate Oxidase Deficiency
Medicure
Phase 3
15
Alabama, California, Colorado, Massachusetts, North Carolina, Ohio
2024-02-16
Recruiting
Amicus Therapeutics
Observational
500
Arkansas, California, Florida, Georgia, Indiana, Missouri, New York, North Carolina
2024-02-16
Active, closed
Boehringer Ingelheim
Phase 3
428
Alabama, Arizona, California, Missouri, Nevada, New York, North Carolina, Ohio
2024-02-09
Recruiting
InSilico Medicine Hong Kong Limited
Phase 2
40
Alabama, Arizona, California, Florida, North Carolina, Oklahoma, Pennsylvania, South Carolina
2024-02-08
Recruiting
Akeso
Phase 2
90
California, Colorado, Connecticut, Florida, Maryland, Missouri, New York, North Carolina
2024-02-07
Recruiting
Novartis Pharmaceuticals
Observational
40
California, Colorado, District of Columbia, North Carolina, Ohio, Tennessee, Texas
2024-02-06
Recruiting
Quanta Therapeutics
Phase 1
250
California, Colorado, Connecticut, Florida, New York, North Carolina, Oklahoma, Tennessee
2024-02-05
Active, closed
Autus Valve Pivotal Study
NCT05006404Congenital Heart Disease
Edwards Lifesciences
Not applicable
62
California, Colorado, Georgia, Illinois, Massachusetts, Michigan, New York, North Carolina
2024-02-05
Active, closed
Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)
NCT05853575Advanced Cancer, Metastatic Cancer, Malignant Neoplasm of Lung
DrugAdagrasib
Mirati Therapeutics Inc.
Phase 2
200
California, Missouri, North Carolina, Texas
2024-02-01
Recruiting
Registry of Patients With AQP4+ NMOSD Treated With Alexion C5 Inhibitor Therapies
NCT05966467Neuromyelitis Optica Spectrum Disorder, NMOSD, AQP4+ NMOSD
Alexion Pharmaceuticals, Inc.
Observational
122
District of Columbia, Massachusetts, North Carolina, Ohio, Texas, Wisconsin
2024-02-01
Active, closed
ReCode Therapeutics
Phase 2
128
Alabama, Arizona, California, Colorado, Georgia, Massachusetts, New York, North Carolina
2024-02-01
Recruiting
Vividion Therapeutics, Inc.
Phase 1
280
Arizona, California, Georgia, Illinois, Kentucky, Michigan, New Jersey, North Carolina
2024-01-25
Recruiting
Zai Lab (Shanghai) Co., Ltd.
Phase 1
339
California, Connecticut, Florida, Michigan, New Jersey, New York, North Carolina, Ohio
2024-01-23
Active, closed
Avidity Biosciences, Inc.
Phase 2
39
Arkansas, California, Georgia, Massachusetts, Minnesota, North Carolina, Ohio, Texas
2024-01-22
Active, closed
A Phase 1/1b Study of ZH9 Treatment in Patients With Non-Muscle Invasive Bladder Cancer
NCT06181266NMIBC, High Risk NMIBC, Non Muscle Invasive Bladder Cancer
Prokarium Ltd
Phase 1
22
California, North Carolina, South Carolina, Texas
2024-01-08
Recruiting
Daiichi Sankyo
Phase 3
50
Florida, North Carolina
2024-01-05
By invitation
Sanofi
Phase 3
90
Arizona, Florida, Illinois, Kentucky, Minnesota, New York, North Carolina, Ohio
2024-01-03
Active, closed
Alexion Pharmaceuticals, Inc.
Phase 3
124
Indiana, New York, North Carolina, Ohio, Tennessee
2024-01-03
Active, closed
Merck Sharp & Dohme LLC
Phase 3
340
Arizona, California, Colorado, Massachusetts, Michigan, Nevada, New York, North Carolina
2023-12-31
Recruiting
CytoAgents, Inc.
Phase 1/2
54
California, Georgia, Massachusetts, North Carolina, Pennsylvania, Washington
2023-12-28
Recruiting
Aadi Bioscience, Inc.
Phase 2
29
Arkansas, Florida, Nevada, New York, North Carolina, Oklahoma, Rhode Island, Texas
2023-12-28
Recruiting
Travere Therapeutics, Inc.
Phase 3
70
Arizona, Connecticut, Georgia, Illinois, Maine, Maryland, New York, North Carolina
2023-12-28
Recruiting
Invenio Imaging Inc.
Observational
900
California, Florida, Michigan, New York, North Carolina, Texas
2023-12-21
Recruiting
Janssen Research & Development, LLC
Phase 1
300
California, Colorado, Florida, Georgia, Michigan, New Jersey, New York, North Carolina
2023-12-20
Recruiting
Ascentage Pharma Group Inc.
Phase 3
400
Arizona, California, Florida, Illinois, Massachusetts, Michigan, North Carolina, Texas
2023-12-20
Active, closed
TransThera Sciences (Nanjing), Inc.
Phase 3
200
California, Florida, Illinois, Massachusetts, Michigan, Minnesota, New York, North Carolina
2023-12-20
Recruiting
Regeneron Pharmaceuticals
Phase 1/2
149
California, Colorado, Kentucky, Michigan, New Jersey, New York, North Carolina, Texas
2023-12-19
Recruiting
Regeneron Pharmaceuticals
Phase 3
822
Arizona, California, Indiana, Massachusetts, Michigan, Mississippi, New York, North Carolina
2023-12-12
Active, closed
A Study to Investigate GB-0895 in Adults With Mild to Moderate Asthma or COPD
NCT07116889Asthma, COPD (Chronic Obstructive Pulmonary Disease)
DrugGB-0895
Generate Biomedicines
Phase 1
156
Florida, Minnesota, North Carolina, Texas
2023-12-12
Active, closed
Sanofi
Phase 2
197
California, Colorado, Florida, Idaho, Illinois, Massachusetts, New York, North Carolina
2023-12-11
Active, closed
Denali Therapeutics Inc.
Phase 1/2
20
California, Iowa, North Carolina, Texas
2023-12-07
Recruiting
Incyte Corporation
Phase 1
290
California, Florida, Kansas, Maryland, Massachusetts, Missouri, New York, North Carolina
2023-12-04
Recruiting
BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors
NCT06120283Advanced Solid Tumor, Advanced Breast Cancer, Metastatic Breast Cancer, Hormone-receptor-positive Breast Cancer
DrugsBGB-43395·Elacestrant·Letrozole·Fulvestrant
BeOne Medicines
Phase 1
433
Colorado, Florida, Michigan, North Carolina, Ohio, Tennessee, Texas
2023-12-01
Active, closed
Bristol-Myers Squibb
Observational
331
North Carolina
2023-12-01
Active, closed
BioNTech SE
Phase 1
41
Michigan, North Carolina, Ohio
2023-11-30
Active, closed
Sanofi
Phase 4
69
California, Florida, Idaho, Illinois, Iowa, Massachusetts, Minnesota, North Carolina
2023-11-29
Active, closed
GlaxoSmithKline
Phase 1
127
Arizona, Florida, Georgia, North Carolina, Oregon, Pennsylvania, South Carolina, Texas
2023-11-27
Recruiting
Novartis Pharmaceuticals
Phase 2/3
232
California, District of Columbia, Florida, Massachusetts, Missouri, North Carolina, Ohio, Oregon
2023-11-24
Active, closed
Gilead Sciences
Phase 2
253
Alabama, California, District of Columbia, Georgia, Massachusetts, New Jersey, New York, North Carolina
2023-11-17
Recruiting
Efficacy of M640 in Acute Lumbosacral Musculoskeletal Conditions.
NCT06157177Sciatica Acute, Lumbar Spinal Stenosis
DrugMetaxalone
Primus Pharmaceuticals
Phase 4
50
Alabama, California, Florida, Georgia, Michigan, New Mexico, North Carolina, Ohio
2023-11-15
Recruiting
FetalEase Ltd.
Not applicable
80
Florida, Idaho, North Carolina, Virginia
2023-11-15
Recruiting
AbbVie
Phase 1
325
California, Colorado, Florida, Illinois, Michigan, Missouri, New York, North Carolina
2023-11-09
Recruiting
Mavacamten Pregnancy Surveillance Program
NCT05939700Breastfeeding, Hypertrophic Cardiomyopathy, Pregnancy Related
DrugMavacamten
Bristol-Myers Squibb
Observational
20
North Carolina
2023-11-09
Recruiting
Jazz Pharmaceuticals
Phase 1
177
California, Colorado, Florida, North Carolina, Pennsylvania, Tennessee, Texas, Virginia
2023-11-07
Recruiting
Exegi Pharma, LLC
Phase 1/2
50
California, Florida, Michigan, Minnesota, Missouri, New York, North Carolina, Pennsylvania
2023-11-06
Recruiting
MISHA Post-Market Clinical Study
NCT06118892Osteo Arthritis Knee
Moximed
Not applicable
120
California, North Carolina, Oregon, Virginia
2023-11-03
Active, closed
Pacific Edge Limited
Observational
1,000
California, North Carolina, Texas
2023-11-02
Recruiting
Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma (TRIgnite-1)
NCT05862012Relapsed/Refractory Multiple Myeloma
Ichnos Sciences SA
Phase 1
200
California, Florida, Georgia, Illinois, Massachusetts, New York, North Carolina, Tennessee
2023-11-01
Recruiting
Janssen Research & Development, LLC
Phase 1
355
Colorado, Georgia, Minnesota, New Jersey, New York, North Carolina, Oregon, Pennsylvania
2023-11-01
Active, closed
Ipsen
Observational
1,057
California, Florida, Maryland, Massachusetts, Missouri, Nebraska, Nevada, North Carolina
2023-11-01
Recruiting
VALOR: Vaginal Atrophy & Long-term Observation of Recovery
NCT05953090Atrophic Vaginitis, Vaginal Atrophy, Genitourinary Syndrome of Menopause, Lichen Sclerosus of Vulva
Stratpharma AG
Not applicable
2,000
Alabama, California, Florida, Georgia, Nevada, North Carolina, South Carolina, Tennessee
2023-10-30
Recruiting
Biogen
Observational
908
Colorado, North Carolina
2023-10-27
Recruiting
Indapta Therapeutics, INC.
Phase 1/2
128
California, Florida, Georgia, Minnesota, New York, North Carolina, Ohio, Oregon
2023-10-25
Recruiting
Bristol-Myers Squibb
Phase 1
140
California, Florida, Massachusetts, New York, North Carolina, Texas, Washington
2023-10-18
Recruiting
Sofwave Medical LTD
Not applicable
100
California, North Carolina
2023-10-11
Active, closed
XVIVO Heart Perfusion System (XHPS) With Supplemented XVIVO Heart Solution (SXHS)
NCT05881278Heart Failure, Transplant; Failure, Heart
XVIVO Perfusion
Not applicable
141
California, Georgia, Illinois, Maryland, Missouri, Nebraska, New York, North Carolina
2023-10-10
Active, closed
Expanded Indications in the Pediatric BONEBRIDGE Population
NCT05615649Hearing Loss, Conductive, Hearing Loss, Mixed
Med-El Corporation
Not applicable
36
Colorado, Florida, New Jersey, North Carolina, Ohio, Utah
2023-10-03
By invitation
Biogen
Phase 3
306
Alabama, Arizona, California, Michigan, Missouri, North Carolina, Ohio, Pennsylvania
2023-10-03
Recruiting
AbbVie
Phase 3
90
Arizona, District of Columbia, New York, North Carolina, Ohio, Oregon
2023-10-02
Recruiting
Starton Therapeutics, Inc
Phase 1/2
24
North Carolina, Ohio
2023-10-02
Recruiting
FBD Biologics Limited
Phase 1
80
Florida, North Carolina, South Carolina, Texas
2023-10-02
Recruiting
Bausch Health Americas, Inc.
Phase 4
70
California, Indiana, New York, North Carolina
2023-09-29
Recruiting
Ipsen
Observational
20
North Carolina
2023-09-28
Recruiting
Pierre Fabre Medicament
Phase 1/2
345
California, North Carolina, Pennsylvania, Tennessee, Texas, Utah, Virginia
2023-09-26
Active, closed
Real World Registry for Use of the Ion Endoluminal System
NCT06004440Lung Cancer, Multiple Pulmonary Nodules, Lung Neoplasms, Respiratory Tract Neoplasms
Intuitive Surgical
Observational
1,301
Florida, Illinois, Kansas, Louisiana, Michigan, Minnesota, New York, North Carolina
2023-09-21
By invitation
Denali Therapeutics Inc.
Phase 2/3
99
California, Illinois, New Jersey, North Carolina, Ohio, Pennsylvania, Texas, Utah
2023-09-20
Recruiting
Regeneron Pharmaceuticals
Phase 3
410
California, Florida, Kentucky, New York, North Carolina, Oregon, Texas, Washington
2023-09-18
Recruiting
Iterion Therapeutics
Phase 1/2
178
California, Florida, Illinois, North Carolina, Texas, Washington
2023-09-13
Recruiting
Incyte Corporation
Observational
958
North Carolina
2023-09-13
Active, closed
Venclose digiRF System Post Market Study
NCT05504070Venous Reflux, Chronic Venous Insufficiency
C. R. Bard
Not applicable
203
Colorado, Hawaii, Michigan, New Jersey, North Carolina, Texas, Virginia
2023-09-08
Recruiting
Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
NCT06040541Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC), Pancreatic Ductal Adenocarcinoma (PDAC), Advanced Solid Tumors
DrugsRMC-9805·Cetuximab
Revolution Medicines, Inc.
Phase 1
604
California, Connecticut, Florida, Maryland, Massachusetts, New York, North Carolina, Ohio
2023-09-07
Recruiting
A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)
NCT05652686Small Cell Lung Cancer (SCLC), Large Cell Neuroendocrine Cancer (LCNEC), Neuroendocrine Prostate Cancer (NEPC), Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC)
DrugsLurbinectedin·Topotecan·Irinotecan·Etoposide
Phanes Therapeutics
Phase 1/2
203
California, Colorado, Connecticut, Maryland, Massachusetts, Missouri, North Carolina, Oklahoma
2023-09-05
Recruiting
SPEARHEAD-3 Pediatric Study
NCT05642455Synovial Sarcoma, Malignant Peripheral Nerve Sheath Tumor (MPNST), Neuroblastoma (NBL), Osteosarcoma
USWM CT, LLC
Phase 1/2
20
California, Maryland, Massachusetts, Missouri, New York, North Carolina, Ohio, Pennsylvania
2023-09-01
By invitation
Disc Medicine, Inc
Phase 2/3
230
Alabama, California, Florida, Massachusetts, New York, North Carolina, Ohio, Pennsylvania
2023-08-31
Active, closed
AnaptysBio, Inc.
Phase 2
420
Arizona, California, Florida, Illinois, Louisiana, Massachusetts, New Mexico, North Carolina
2023-08-31
Recruiting
Pliant Therapeutics, Inc.
Phase 1
124
Connecticut, Georgia, Michigan, Missouri, New Jersey, New York, North Carolina, South Dakota
2023-08-30
By invitation
CSL Behring
Observational
56
Arizona, Arkansas, California, Colorado, Florida, Michigan, North Carolina, Oregon
2023-08-30
Recruiting
Rocket Pharmaceuticals Inc.
Phase 1
9
California, North Carolina, Pennsylvania
2023-08-29
Active, closed
Ocugen
Phase 2/3
51
Arizona, California, Florida, Indiana, Massachusetts, Mississippi, Missouri, North Carolina
2023-08-25
Recruiting
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction
NCT06061549Heart Failure, Diastolic, Heart Failure With Preserved Ejection Fraction
Sardocor Corp.
Phase 1
10
North Carolina, Texas
2023-08-24
Active, closed
A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma
NCT05929235Advanced Urothelial Carcinoma, Oral Drug Administration, Open Label
DrugsKeytruda·Pembrolizumab
Flare Therapeutics Inc.
Phase 1
120
California, Connecticut, Florida, Illinois, Massachusetts, New York, North Carolina, Ohio
2023-08-24
Recruiting
Atsena Therapeutics Inc.
Phase 3
97
Arizona, California, Florida, Massachusetts, Michigan, Minnesota, New York, North Carolina
2023-08-22
Recruiting
CERAMENT G Device Registry
NCT06010433Chronic Osteomyelitis, Fracture Related Infection, Diabetic Foot Osteomyelitis
BONESUPPORT AB
Observational
100
California, North Carolina, Ohio
2023-08-17
Active, closed
Target PharmaSolutions, Inc.
Observational
500,000
North Carolina
2023-08-01
Recruiting
AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma
NCT05602363B-cell Malignancy, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Waldenstrom Macroglobulinemia
Carna Biosciences, Inc.
Phase 1
120
California, Florida, Illinois, Indiana, Maryland, Massachusetts, New York, North Carolina
2023-08-01
Active, closed
Belite Bio, Inc
Phase 3
429
Arizona, California, Florida, Maryland, Minnesota, New York, North Carolina, Oregon
2023-07-27
Recruiting
ReAlta Life Sciences, Inc.
Phase 2
70
Arkansas, California, Florida, Indiana, Kentucky, Massachusetts, Missouri, North Carolina
2023-07-27
Active, closed
Abbott Ventricular Tachycardia PAS
NCT05839873Ventricular Tachycardia
Abbott Medical Devices
Observational
62
Florida, Indiana, Kansas, Massachusetts, Minnesota, North Carolina, Oklahoma, South Carolina
2023-07-24
Recruiting
Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma
NCT05879367Glioblastoma, IDH-wildtype, Glioblastoma, Glioblastoma Multiforme, Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
DrugsDFMO·Eflornithine·Temodar·Temozolomide
Orbus Therapeutics, Inc.
Phase 1
66
Alabama, Michigan, New York, North Carolina, Ohio, Rhode Island, Texas, Utah
2023-07-24
Active, closed
Eagle Pharmaceuticals, Inc.
Phase 2
276
California, Florida, Illinois, Nebraska, North Carolina, Ohio, Texas
2023-07-22
Recruiting
Lin BioScience, Inc
Phase 1/2
90
Florida, Illinois, Kansas, Maryland, North Carolina
2023-07-20
Recruiting
Carevive Systems, Inc.
Observational
25
Connecticut, Illinois, North Carolina, Ohio
2023-07-19
Recruiting
Amicus Therapeutics
Phase 3
36
Florida, Georgia, North Carolina, Ohio, Pennsylvania, Utah
2023-07-18
Active, closed
Hoffmann-La Roche
Phase 2
83
California, New York, North Carolina, South Dakota
2023-07-18
Recruiting
Caption Health, Inc.
Not applicable
220
Connecticut, Illinois, North Carolina
2023-07-17
Recruiting
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
NCT05877599Non-small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Colorectal Carcinoma, Pancreatic Adenocarcinoma
AstraZeneca
Phase 1
45
Arizona, California, Florida, Massachusetts, New Jersey, New York, North Carolina, Oregon
2023-07-12
Active, closed
Incyte Corporation
Phase 2
247
Alabama, California, Florida, Georgia, Illinois, Michigan, New York, North Carolina
2023-07-11
Recruiting
Krystal Biotech, Inc.
Phase 1
20
Florida, Idaho, Illinois, New York, North Carolina
2023-06-30
Active, closed
Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform (ELEPHAS-02)
NCT05520099Immunotherapy, Cancer, Bladder Cancer, Urothelial Carcinoma Bladder
Elephas
Observational
416
Arkansas, California, Florida, Kentucky, Maryland, New Jersey, New York, North Carolina
2023-06-26
Active, closed
Alexion Pharmaceuticals, Inc.
Phase 3
12
California, Massachusetts, North Carolina, Pennsylvania
2023-06-24
Recruiting
NIBP Validation Study
NCT05673408Critical Illness
Philips Clinical & Medical Affairs Global
Observational
189
Florida, North Carolina, Oregon, Texas, Utah
2023-06-23
Active, closed
Merck Sharp & Dohme LLC
Phase 1/2
390
California, Colorado, Georgia, Indiana, Massachusetts, Missouri, New York, North Carolina
2023-06-23
Recruiting
A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies
NCT05780034Relapsed/Refractory B-cell Malignancies
Accutar Biotechnology Inc
Phase 1
60
Colorado, Florida, North Carolina, Ohio, Oregon, Tennessee, Texas, Washington
2023-06-20
Recruiting
Piomic Medical
Not applicable
450
Arizona, California, Florida, Georgia, Illinois, New Jersey, New York, North Carolina
2023-06-19
Active, closed
Foundry Innovation & Research 1, Limited (FIRE1)
Not applicable
25
Minnesota, New York, North Carolina, Ohio, South Carolina, Texas
2023-06-19
Recruiting
GlaxoSmithKline
Phase 1/2
123
Arizona, California, Florida, Massachusetts, Michigan, North Carolina, Ohio, Tennessee
2023-06-14
Active, closed
Safety and Pharmacodynamics of GNSC-001 Intra-articular Injection for Knee Osteoarthritis
NCT05835895Osteoarthritis, Knee, Osteo Arthritis Knee, Knee Osteoarthritis
Genascence Corporation
Phase 1
67
Alabama, California, Florida, Missouri, North Carolina, Pennsylvania
2023-06-12
Active, closed
Post-Market Registry in Europe and US for the Use of VascuCelTM
NCT04906824Great Vessel Reconstruction, Peripheral Vessel Reconstruction, Suture Line Buttressing
LeMaitre Vascular
Observational
100
Idaho, Nevada, New York, North Carolina
2023-06-09
Recruiting
H. Lundbeck A/S
Phase 3
315
Connecticut, Florida, Georgia, Kentucky, Maryland, Michigan, New York, North Carolina
2023-06-08
Active, closed
Pelvic Fixation and Fusion During Multilevel Spinal Surgery
NCT05640908Spinal Fusion, Deformity of Spine
SI-BONE, Inc.
Observational
200
Alabama, Colorado, Michigan, Minnesota, New York, North Carolina, Texas
2023-06-05
Active, closed
Sapience Therapeutics
Phase 1
130
Alabama, California, Colorado, Louisiana, Massachusetts, Michigan, New York, North Carolina
2023-06-05
Recruiting
Vanda Pharmaceuticals
Phase 4
100
Alabama, Arkansas, Colorado, Georgia, North Carolina, Ohio, Washington
2023-05-24
Active, closed
Translational Sciences, Inc.
Phase 2
64
Arizona, California, Georgia, Maryland, Massachusetts, Michigan, North Carolina, Ohio
2023-05-24
Recruiting
Vaneltix Pharma, Inc.
Phase 2
120
California, Florida, Georgia, Louisiana, Massachusetts, Nevada, New York, North Carolina
2023-05-22
Active, closed
Lexeo Therapeutics
Phase 1
10
Florida, North Carolina
2023-05-08
Recruiting
Sumitomo Pharma Switzerland GmbH
Observational
728
North Carolina
2023-05-08
Active, closed
AbbVie
Phase 1
39
Arizona, Florida, Minnesota, Nebraska, New York, North Carolina, Texas
2023-04-26
Active, closed
Nevro Corp
Not applicable
143
North Carolina, Oregon
2023-04-24
Active, closed
Regeneron Pharmaceuticals
Phase 2
51
California, Kentucky, New Mexico, New York, North Carolina, Texas, Virginia, Washington
2023-04-21
Active, closed
Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies
NCT05783622Non-Small Cell Lung Cancer, Renal Cell Carcinoma, Squamous Cell Carcinoma of the Head and Neck, Colorectal Carcinoma
Janux Therapeutics
Phase 1
130
California, Georgia, Illinois, Michigan, Missouri, New York, North Carolina, Ohio
2023-04-19
Active, closed
Legend Biotech USA Inc
Phase 1
56
Florida, Michigan, New Jersey, New York, North Carolina, Oregon, Tennessee, Washington
2023-04-18
Active, closed
Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma
NCT05561374High-grade Glioma, Oligodendroglioma, Astrocytoma, Glioblastoma Multiforme
Oblato, Inc.
Phase 1
16
California, Kentucky, North Carolina, Oklahoma
2023-04-17
Recruiting
Study of SGR-1505 in Mature B-Cell Neoplasms
NCT05544019Mature B-Cell Neoplasm, Non Hodgkin Lymphoma, DLBCL, Waldenstrom Macroglobulinemia
Schrödinger, Inc.
Phase 1
98
Arizona, Delaware, Florida, Massachusetts, New Jersey, New York, North Carolina, Ohio
2023-04-10
Recruiting
Takeda
Phase 2/3
500
Alabama, California, Colorado, Florida, Georgia, Massachusetts, Michigan, North Carolina
2023-04-05
Active, closed
Study to Evaluate Adverse Events and Change in Disease Activity in Adult Participants With B-Cell Malignancies Receiving Oral ABBV-525 Tablets
NCT05618028Diffuse Large B-Cell Lymphoma, Chronic Lymphocytic Leukemia, B Cell Malignancies, Non-Hodgkin's Lymphoma
AbbVie
Phase 1
78
California, Connecticut, Florida, Indiana, Louisiana, Michigan, New York, North Carolina
2023-04-04
Active, closed
NuvOx LLC
Phase 2
87
Arizona, California, Connecticut, Illinois, Louisiana, Missouri, New Jersey, North Carolina
2023-03-31
Active, closed
Hoffmann-La Roche
Phase 3
85
California, Florida, Georgia, New Jersey, North Carolina, Utah, Virginia
2023-03-29
Recruiting
Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer
NCT05735080Breast Cancer, Breast Cancer Metastatic, Hormone Receptor Positive Tumor, Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
DrugsAbemaciclib·Fulvestrant
Incyclix Bio
Phase 1/2
150
Florida, Georgia, Indiana, Massachusetts, Michigan, New York, North Carolina, Ohio
2023-03-28
Recruiting
Incyte Corporation
Observational
5,621
North Carolina
2023-03-27
Recruiting
Genentech, Inc.
Phase 2
60
California, Florida, Maryland, Missouri, Nevada, North Carolina, Ohio, Pennsylvania
2023-03-23
Active, closed
Imvax
Phase 2
99
Florida, Massachusetts, Michigan, New Hampshire, New Jersey, New York, North Carolina, Ohio
2023-03-20
Recruiting
Vega Therapeutics, Inc
Phase 1/2
116
California, Colorado, Georgia, North Carolina, Pennsylvania, Tennessee, Texas, Washington
2023-03-16
Recruiting
Phanes Therapeutics
Phase 1/2
350
California, Colorado, Iowa, Kentucky, Massachusetts, North Carolina, Pennsylvania, Texas
2023-03-15
Recruiting
Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment
NCT05327062Cardiac Resynchronization Therapy, Chronic Heart Failure, Left Bundle-Branch Block
XSpline S.p.A.
Not applicable
150
Illinois, Massachusetts, North Carolina
2023-03-06
Active, closed
Miach Orthopaedics
Observational
300
California, Colorado, Florida, New Jersey, New York, North Carolina, Oregon
2023-02-28
Active, closed
Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term Application
NCT05094089Hernia, Ventral, Hernia Incisional, Hernia Incisional Ventral
W.L.Gore & Associates
Observational
320
Georgia, Massachusetts, Michigan, New Mexico, New York, North Carolina, South Carolina, Virginia
2023-02-24
Active, closed
Ocugen
Phase 1/2
60
Arizona, Florida, Indiana, Mississippi, Missouri, New Jersey, North Carolina, Pennsylvania
2023-02-23
Recruiting
K36 Therapeutics, Inc.
Phase 1
165
California, Florida, Georgia, Massachusetts, Minnesota, New Jersey, New York, North Carolina
2023-02-22
Recruiting
BioMarin Pharmaceutical
Observational
170
California, Maryland, North Carolina, Ohio, South Dakota, Texas, Wisconsin
2023-02-21
Active, closed
ModernaTX, Inc.
Phase 1
186
California, District of Columbia, Illinois, Louisiana, North Carolina, Rhode Island, South Carolina, Tennessee
2023-02-15
Active, closed
A Safety and Efficacy Study of PVX108 in Children and Adolescents With Peanut Allergy
NCT05621317Peanut Allergy, Peanut Hypersensitivity, Peanut-Induced Anaphylaxis, Immune System Diseases
Aravax Pty Ltd
Phase 2
90
Arkansas, California, Georgia, Indiana, Maryland, Massachusetts, North Carolina
2023-02-09
Recruiting
Home Sleep Therapy for Older Adults With MCI
NCT05771844Mild Cognitive Impairment, Sleep, Transcranial Electrical Stimulation, Machine Learning
Brain Electrophysiology Laboratory Company
Not applicable
60
North Carolina, Oregon
2023-02-08
Recruiting
Caribou Biosciences, Inc.
Phase 1
50
Alabama, Colorado, Florida, Kentucky, New Jersey, New York, North Carolina, Ohio
2023-02-06
Active, closed
Forge Biologics, Inc
Phase 1/2
9
California, Michigan, North Carolina
2023-02-03
Active, closed
Astellas Pharma Global Development, Inc.
Phase 1/2
70
California, Colorado, Florida, Illinois, Maryland, New York, North Carolina, Ohio
2023-01-31
Active, closed
Observational Lung Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform (ELEPHAS-01)
NCT05478538NSCLC (Non-small Cell Lung Cancer), Metastatic NSCLC - Non-Small Cell Lung Cancer
Elephas
Observational
200
California, Maryland, New York, North Carolina, Ohio, Texas
2023-01-31
Active, closed
Biocomposites Ltd
Phase 2
61
Arizona, Arkansas, Nevada, New Jersey, New York, North Carolina
2023-01-23
By invitation
NuVasive
Observational
158
North Carolina, Texas
2023-01-18
Active, closed
Sanofi
Phase 2
68
California, Florida, Georgia, New Jersey, New York, North Carolina, Pennsylvania, Texas
2023-01-12
Recruiting
AbbVie
Observational
1,884
North Carolina
2023-01-10
Active, closed
Calcilytix Therapeutics, Inc., a BridgeBio company
Phase 3
67
California, Colorado, Indiana, Maryland, Massachusetts, Minnesota, New York, North Carolina
2023-01-06
By invitation
Tolmar Inc.
Phase 3
250
California, Florida, Kentucky, Maryland, New York, North Carolina, Pennsylvania, Tennessee
2022-12-28
Recruiting
Grifols Therapeutics LLC
Phase 3
386
Arizona, California, Florida, Maryland, North Carolina, Ohio, South Carolina
2022-12-26
Active, closed
Prevail Therapeutics
Phase 1/2
8
North Carolina, Virginia
2022-12-20
Recruiting
Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test
NCT06864338Colorectal Cancer Screening, Colorectal Cancer Metastatic, Colon Adenocarcinoma
Mainz Biomed
Observational
2,700
North Carolina
2022-12-18
Active, closed
Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO)
NCT05696444Bladder Cancer, Prostate Cancer, Kidney Cancer, Pelvic Tumor
Medtronic - MITG
Not applicable
144
California, Illinois, New York, North Carolina, Ohio, Washington
2022-12-14
Active, closed
Shanton Pharma Pte. Ltd.
Phase 2
87
California, Colorado, Florida, Idaho, Maryland, Mississippi, North Carolina, Texas
2022-12-12
Active, closed
BioNTech SE
Phase 1
318
Arizona, Illinois, North Carolina, Ohio, Pennsylvania
2022-12-08
Recruiting
[18F]PI-2620 Phase 3 Histopathological Study
NCT05641688Alzheimer Disease
Lantheus Biosciences Ltd.
Phase 3
200
Arizona, California, Florida, Massachusetts, Nebraska, New Hampshire, New York, North Carolina
2022-12-01
Recruiting
A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis
NCT05652335Relapsed or Refractory Multiple Myeloma, Previously Treated Amyloid Light-chain (AL) Amyloidosis
DrugRamantamig
Janssen Research & Development, LLC
Phase 1
180
California, Colorado, New York, North Carolina, Pennsylvania, Texas
2022-11-22
Active, closed
Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations
NCT05544552Locally Advanced Urothelial Carcinoma, Metastatic Urothelial Carcinoma, Solid Tumor, Urothelial Carcinoma
DrugTYRA-300
Tyra Biosciences, Inc
Phase 1/2
310
Massachusetts, New York, North Carolina, Ohio, Tennessee, Washington
2022-11-22
Recruiting
BioMarin Pharmaceutical
Observational
50
North Carolina
2022-11-22
Active, closed
Novartis Pharmaceuticals
Phase 3
568
Colorado, Illinois, Minnesota, North Carolina, Ohio, Oregon, Texas, Virginia
2022-11-21
Active, closed
Study of Iadademstat and Gilteritinib in Patients With R/R AML With FMS-like Tyrosine Kinase Mutation (FLT3 Mut+)
NCT05546580Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
DrugsXospata·Gilteritinib
Oryzon Genomics S.A.
Phase 1
50
Arizona, Florida, Maryland, Massachusetts, New Jersey, New York, North Carolina, Oregon
2022-11-14
Active, closed
SoniVie Inc.
Not applicable
25
Alabama, Arkansas, Connecticut, Illinois, Minnesota, New York, North Carolina, South Carolina
2022-11-11
Active, closed
Agios Pharmaceuticals, Inc.
Phase 2
87
California, Connecticut, Florida, Illinois, Missouri, New York, North Carolina
2022-11-07
Active, closed
Hoffmann-La Roche
Phase 1
121
California, Colorado, Florida, Illinois, North Carolina, Texas
2022-10-26
Active, closed
The GORE® VIABAHN® FORTEGRA Venous Stent IVC Study
NCT05409976Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis
W.L.Gore & Associates
Not applicable
136
California, District of Columbia, Illinois, Michigan, New York, North Carolina, Virginia
2022-10-25
Active, closed
SPR Therapeutics, Inc.
Not applicable
50
California, Massachusetts, Minnesota, North Carolina, Texas, Utah
2022-10-24
Active, closed
AbbVie
Phase 1
283
Arkansas, Florida, Maryland, Massachusetts, Michigan, New Jersey, New York, North Carolina
2022-10-20
Recruiting
Urovant Sciences GmbH
Phase 2/3
71
Arkansas, California, Colorado, Florida, Kansas, Louisiana, New York, North Carolina
2022-10-12
Recruiting
M-Vizion™ Macroscopic Radiographic Study
NCT05721859Revision Hip Arthroplasty
Medacta USA
Observational
70
Illinois, Massachusetts, New Hampshire, North Carolina, Pennsylvania, Utah
2022-10-12
Active, closed
Gilead Sciences
Phase 3
1,021
California, District of Columbia, Florida, Illinois, North Carolina, Ohio, Oregon, Pennsylvania
2022-10-12
Active, closed
Bayer
Phase 1
129
Illinois, North Carolina, Texas, Utah
2022-10-11
Active, closed
Genmab
Phase 1
17
California, Florida, New York, North Carolina, Ohio, Pennsylvania, Tennessee, Texas
2022-10-04
Active, closed
Janssen Research & Development, LLC
Phase 1
196
Alabama, California, Massachusetts, New York, North Carolina, Texas
2022-10-04
Recruiting
Outcomes Following Combined Adductoplasty™ and Lapiplasty® (MTA3D)
NCT05587569Metatarsus Adductus, Hallux Valgus
Treace Medical Concepts, Inc.
Not applicable
80
Colorado, Iowa, Maine, Missouri, North Carolina, Ohio, Pennsylvania, Texas
2022-09-28
Active, closed
Kite, A Gilead Company
Phase 3
231
California, Florida, Kansas, Maryland, Massachusetts, North Carolina, Pennsylvania, Tennessee
2022-09-22
Recruiting
Rigel Pharmaceuticals
Phase 1/2
86
California, Florida, Missouri, New Jersey, New York, North Carolina, Ohio, Texas
2022-09-12
Recruiting
Teligene US
Phase 2
99
California, Georgia, Kentucky, Maryland, North Carolina, Texas
2022-09-01
Recruiting
Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.
NCT05422911Metastatic Cancer, Neoplasm, Prostate, Castrate-sensitive, Castrate-sensitive Prostate Cancer
DrugsZytiga·Apalutamide·Xtandi·Abiraterone acetate
Sun Pharmaceutical Industries Limited
Phase 2
192
California, Florida, Michigan, Missouri, New York, North Carolina, Oregon, Pennsylvania
2022-08-31
Active, closed
Biogen
Phase 2
416
Arizona, California, Colorado, Florida, Hawaii, Massachusetts, New York, North Carolina
2022-08-24
Active, closed
Amgen
Phase 1
184
California, Delaware, Michigan, New Jersey, New York, North Carolina, South Dakota, Washington
2022-08-24
Recruiting
Takeda
Phase 3
440
Arkansas, California, Colorado, Florida, New Jersey, North Carolina, Ohio, Oklahoma
2022-08-24
Active, closed
Cochlear
Not applicable
60
California, Colorado, Iowa, New York, North Carolina, Washington
2022-08-19
By invitation
argenx
Phase 2/3
12
Illinois, North Carolina, Virginia
2022-08-18
Recruiting
Regeneron Pharmaceuticals
Phase 1
317
California, Georgia, Indiana, Massachusetts, Michigan, Minnesota, New York, North Carolina
2022-08-17
Active, closed
A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma
NCT05421663Lymphoma, Non-Hodgkin, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse
Janssen Research & Development, LLC
Phase 1/2
166
California, Colorado, Iowa, Kentucky, New Jersey, North Carolina, Ohio, Pennsylvania
2022-08-12
Recruiting
InSightec
Phase 3
30
Arizona, California, Florida, Maryland, North Carolina, Oregon, Rhode Island, Virginia
2022-08-12
Recruiting
Phanes Therapeutics
Phase 1/2
40
North Carolina, Oklahoma, Tennessee, Texas, Virginia
2022-08-11
Active, closed
GlaxoSmithKline
Phase 3
3,038
Arizona, Maryland, North Carolina, Pennsylvania, Tennessee, Texas, Utah
2022-08-10
Active, closed
Mercator MedSystems, Inc.
Phase 2
60
Connecticut, Florida, Illinois, Louisiana, Maryland, New York, North Carolina, Ohio
2022-08-08
Recruiting
Vertex Pharmaceuticals Incorporated
Phase 3
26
New York, North Carolina, Tennessee
2022-08-02
Active, closed
Daewoong Pharmaceutical Co. LTD.
Phase 2
102
Arizona, California, Illinois, Kansas, Massachusetts, Michigan, Missouri, North Carolina
2022-07-29
Active, closed
A Clinical Study Evaluating a Combination of Oregovomab and Niraparib in Adult Women With Platinum Sensitive Recurrent Ovarian Cancer.
NCT05335993Recurrent Ovarian Cancer, Recurrent Epithelial Cancer of Ovary, Recurrent Epithelial Ovarian Cancer, Recurrent Fallopian Tube Cancer
DrugsOregovomab·Niraparib
CanariaBio Inc.
Phase 2
10
North Carolina, Oklahoma, Virginia
2022-07-25
Active, closed
Autologous CD30.CAR-T in Combination With Nivolumab in cHL Patients After Failure of Frontline Therapy
NCT05352828Classical Hodgkin Lymphoma, Hodgkin Disease Refractory, Hodgkin Disease Recurrent
DrugsFludara·Bendamustine·Opdivo·Fludarabine
Tessa Therapeutics
Phase 1
15
California, Florida, North Carolina, Texas
2022-07-25
Active, closed
PureTech
Phase 2
240
Alabama, California, Connecticut, Florida, Georgia, Indiana, Kansas, North Carolina
2022-07-22
Active, closed
Denali Therapeutics Inc.
Phase 2/3
65
California, Illinois, New Jersey, North Carolina, Ohio, Pennsylvania, Texas, Utah
2022-07-21
Active, closed
SP Thoracic IDE Study
NCT05150210Primary Lung Cancer, Benign Lung Disease, Thymoma, Myasthenia Gravis
Intuitive Surgical
Not applicable
32
California, Massachusetts, New York, North Carolina, Texas
2022-07-20
Active, closed
GlaxoSmithKline
Phase 3
163
Colorado, Florida, Minnesota, New York, North Carolina, Pennsylvania
2022-07-14
Recruiting
Locus Biosciences
Phase 2
318
California, Florida, Massachusetts, Missouri, North Carolina
2022-07-13
Active, closed
A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies
NCT05362773Leukemia, Acute Myeloid, Myelodysplastic Syndromes, Classical Hodgkin Lymphoma, Leukemia, B-cell
MacroGenics
Phase 1
130
Colorado, Maryland, Massachusetts, Michigan, Missouri, North Carolina, Texas
2022-07-13
Recruiting
Tempus AI
Observational
200
California, Colorado, Illinois, Maryland, New Jersey, North Carolina, Ohio, Oklahoma
2022-07-13
Active, closed
Ionis Pharmaceuticals, Inc.
Phase 3
154
Arizona, California, Florida, Kansas, Massachusetts, Michigan, Missouri, North Carolina
2022-07-13
Recruiting
Peel Therapeutics Inc
Phase 1
65
Arizona, California, North Carolina, Pennsylvania, Rhode Island, Texas, Utah, Virginia
2022-07-11
Recruiting
Riboscience, LLC.
Phase 1
164
Arizona, California, Delaware, Kentucky, Louisiana, Maryland, New York, North Carolina
2022-07-11
Active, closed
Incyte Corporation
Phase 1
291
California, Colorado, Connecticut, Florida, Georgia, New York, North Carolina, Pennsylvania
2022-07-05
Recruiting
Pfizer
Phase 4
210
Arizona, Georgia, Massachusetts, Minnesota, Missouri, New Jersey, New York, North Carolina
2022-07-05
Recruiting
Octapharma
Phase 3
38
District of Columbia, Florida, Illinois, New York, North Carolina
2022-07-01
Recruiting
BioRestorative Therapies
Phase 2
99
Alabama, California, Colorado, Florida, New York, North Carolina, Ohio, Oklahoma
2022-06-30
Active, closed
Glenmark Specialty S.A.
Phase 1
320
North Carolina, Wisconsin
2022-06-28
Active, closed
3Spine
Not applicable
158
California, Colorado, Florida, Kentucky, Louisiana, Minnesota, New York, North Carolina
2022-06-23
Active, closed
Alexion Pharmaceuticals, Inc.
Phase 2/3
12
District of Columbia, Florida, Massachusetts, North Carolina, Pennsylvania
2022-06-23
Active, closed
Sanofi
Phase 3
531
Colorado, Florida, Mississippi, New Jersey, New York, North Carolina, Ohio, South Carolina
2022-06-23
Recruiting
A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)
NCT05462106Amyloid Plaque, Beta-Amyloid, DSAD, Prodromal Alzheimer's Disease
AC Immune SA
Phase 1/2
304
Arizona, Florida, Indiana, Kansas, Massachusetts, Missouri, North Carolina, Tennessee
2022-06-21
Recruiting
Tempus AI
Observational
300
Arkansas, California, Maryland, Missouri, Nebraska, North Carolina, Ohio, Oklahoma
2022-06-21
Recruiting
Multicenter Clinical Study of the SING-IMT in Patients with Late-stage AMD
NCT05438732Age-Related Macular Degeneration, Geographic Atrophy
VisionCare, Inc.
Not applicable
125
California, Florida, Massachusetts, Michigan, Nebraska, New Jersey, North Carolina, Ohio
2022-06-16
Recruiting
BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHL
NCT05370430Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
PeproMene Bio, Inc.
Phase 1
36
California, Kansas, Minnesota, North Carolina, Washington
2022-06-13
Active, closed
Delcath Systems Inc.
Phase 3
30
California, Florida, North Carolina, Ohio, Tennessee
2022-06-10
Active, closed
Arcus Biosciences, Inc.
Phase 2
332
Arizona, California, Connecticut, Florida, Massachusetts, New York, North Carolina, Ohio
2022-06-10
Active, closed
ProVee Urethral Expander System IDE Study (ProVIDE)
NCT05186740BPH With Symptomatic Lower Urinary Tract Symptoms
ProVerum Medical
Not applicable
221
California, Florida, Illinois, Nevada, New York, North Carolina, Texas, Virginia
2022-06-09
Recruiting
Astellas Pharma Global Development, Inc.
Phase 1
398
California, Illinois, Kansas, New Jersey, New York, North Carolina, Texas, Washington
2022-06-07
Active, closed
Agios Pharmaceuticals, Inc.
Phase 3
30
California, Colorado, Georgia, Illinois, Massachusetts, Michigan, North Carolina, Pennsylvania
2022-06-06
Active, closed
Faron Pharmaceuticals Ltd
Phase 1/2
181
California, Connecticut, North Carolina, Texas
2022-06-02
Active, closed
ModernaTX, Inc.
Phase 1/2
15
Connecticut, Massachusetts, North Carolina, Ohio, Pennsylvania, Texas, Utah
2022-06-01
Recruiting
Congenital Athymia Patient Registry
NCT05329935Complete DiGeorge Anomaly, Complete DiGeorge Syndrome, Congenital Athymia
Sumitomo Pharma Switzerland GmbH
Observational
75
North Carolina
2022-05-25
Active, closed
Janssen Research & Development, LLC
Phase 1
74
Colorado, New York, North Carolina, Tennessee
2022-05-25
Active, closed
Candela Corporation
Not applicable
500
Florida, Massachusetts, North Carolina, Virginia
2022-05-24
By invitation
NuVasive® ACP System Study
NCT05066711Cervical Spondylosis, Cervical Radiculopathy, Cervical Myelopathy, Cervical Disc Disease
NuVasive
Observational
75
Illinois, Missouri, North Carolina
2022-05-22
Active, closed
AbbVie
Phase 1
34
California, Florida, Louisiana, Maryland, Michigan, Minnesota, New York, North Carolina
2022-05-17
Recruiting
REMASTer: REcurrent Brain Metastases After SRS Trial
NCT05124912Brain Metastases, Radiation Necrosis, Recurrent Tumor, Recurrent Metastases
Monteris Medical
Not applicable
261
California, Illinois, Maryland, Missouri, North Carolina, Ohio, Wisconsin
2022-05-10
Recruiting
Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.
NCT04771572Non Hodgkin Lymphoma, Richter Transformation, Multiple Myeloma, T-cell-prolymphocytic Leukemia
Newave Pharmaceutical Inc
Phase 1
100
Illinois, Massachusetts, North Carolina, Ohio, Texas, Utah
2022-05-08
Active, closed
Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD)
NCT05329649Sickle Cell Disease, Hydroxyurea Failure, Hydroxyurea Intolerance, Hemoglobinopathies
DrugExa-cel
Vertex Pharmaceuticals Incorporated
Phase 3
13
North Carolina, Pennsylvania, Tennessee
2022-05-02
Recruiting
InSightec
Observational
50
Florida, Illinois, Massachusetts, New York, North Carolina, Ohio
2022-04-28
Recruiting
MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors
NCT05076760Solid Tumor, Advanced Cancer, Metastatic Cancer, Non Small Cell Lung Cancer
DrugsOpdivo·Docetaxel·Nivolumab
Memgen, Inc.
Phase 1
40
Florida, North Carolina
2022-04-21
Recruiting
Use of CereGate Therapy for Freezing of Gait in PD
NCT05292794Parkinson Disease, Freezing of Gait, Deep Brain Stimulation
CereGate Inc.
Not applicable
41
California, Colorado, Florida, Illinois, North Carolina, Tennessee, Washington
2022-04-18
Recruiting
Ethicon Pelvic Mesh Post Market Clinical Follow-up Registry
NCT04829175Stress Urinary Incontinence, Pelvic Organ Prolapse
Ethicon, Inc.
Observational
1,000
Connecticut, North Carolina, Pennsylvania
2022-04-11
Active, closed
Polaris Group
Phase 1
38
Florida, North Carolina, Texas
2022-04-05
Recruiting
Aulos Bioscience, Inc.
Phase 1/2
159
Florida, Michigan, Minnesota, Missouri, North Carolina, Tennessee, Texas, Utah
2022-04-04
Active, closed
GlaxoSmithKline
Phase 1
152
California, North Carolina, Oklahoma, Pennsylvania, Texas, Utah
2022-03-22
By invitation
Global Utilization And Registry Database for Improved preservAtion of doNor Livers
NCT05082077Liver Diseases, Liver Dysfunction, Liver Transplant Disorder, Liver Transplant Rejection
Paragonix Technologies
Observational
2,000
Alabama, California, Florida, Georgia, Maryland, Massachusetts, Nebraska, North Carolina
2022-03-15
Active, closed
A Phase 3 Study to Examine the Efficacy and Safety of ZX008 in Subjects With CDKL5 Deficiency Disorder.
NCT05064878CDKL5 Deficiency Disorder, Generalized Tonic Clonic Seizure, Epileptic Spasm, Refractory Seizures
DrugFintepla
Zogenix, Inc.
Phase 3
87
Alabama, California, Colorado, District of Columbia, Georgia, Massachusetts, Michigan, North Carolina
2022-03-08
Active, closed
Janssen Research & Development, LLC
Phase 2
151
California, Connecticut, Florida, Georgia, Massachusetts, Michigan, New York, North Carolina
2022-03-01
Active, closed
Nalu Medical, Inc.
Not applicable
89
Arizona, Arkansas, California, Colorado, District of Columbia, North Carolina, Oregon, Texas
2022-02-23
Recruiting
Merck Sharp & Dohme LLC
Phase 2
40
California, Florida, Illinois, North Carolina, Texas
2022-02-22
Active, closed
AstraZeneca
Phase 3
363
Arizona, California, Florida, Georgia, Kentucky, New Jersey, New York, North Carolina
2022-02-15
Active, closed
JCR Pharmaceuticals Co., Ltd.
Phase 3
86
Arizona, California, Illinois, Minnesota, New York, North Carolina, Pennsylvania
2022-02-14
Active, closed
Long-term Assessment of the Safety and Performance of the NuVasive Simplify Disc
NCT05258435Cervical Disc Disease, Degenerative Disc Disease
NuVasive
Observational
131
California, Colorado, Florida, Illinois, Indiana, Louisiana, North Carolina, Texas
2022-02-09
Active, closed
Insignia™ Hip Stem Outcomes Study
NCT05144191Hip Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Post-traumatic Osteoarthritis
Stryker Orthopaedics
Not applicable
313
Arizona, California, Illinois, Nevada, New York, North Carolina, Pennsylvania, Tennessee
2022-02-07
Recruiting
Pfizer
Phase 2
91
North Carolina
2022-02-02
Active, closed
Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System
NCT04770870Osteoarthritis Ankle, Post-Traumatic Osteoarthritis of Ankle, Osteoarthritis of Ankle Secondary to Inflammatory Arthritis (Disorder)
DT MedTech, LLC
Not applicable
94
Arkansas, California, Florida, Indiana, Maryland, New Mexico, North Carolina, Oklahoma
2022-02-01
Active, closed
Biogen
Phase 3
45
Arizona, California, Georgia, Massachusetts, Michigan, New York, North Carolina, Pennsylvania
2022-01-21
Active, closed
ADH1 and ADH2 Disease Monitoring Study (DMS)
NCT05227287Autosomal Dominant Hypocalcemia
Calcilytix Therapeutics, Inc., a BridgeBio company
Observational
95
California, Colorado, Florida, Indiana, Massachusetts, Minnesota, North Carolina, Ohio
2022-01-20
Active, closed
Ascendis Pharma Oncology Division A/S
Phase 1/2
320
California, Illinois, Kentucky, Massachusetts, New Jersey, New York, North Carolina, Ohio
2022-01-11
Active, closed
Ionis Pharmaceuticals, Inc.
Phase 3
151
Arizona, Indiana, Maryland, Massachusetts, New York, North Carolina, Oregon, Washington
2022-01-04
Active, closed
Ionis Pharmaceuticals, Inc.
Phase 1/2
71
California, Colorado, Illinois, Massachusetts, North Carolina, Texas
2021-12-22
Active, closed
ITM Solucin GmbH
Phase 3
259
California, Colorado, Florida, Massachusetts, Minnesota, Missouri, New York, North Carolina
2021-12-21
Active, closed
Smith & Nephew, Inc.
Observational
299
Georgia, Massachusetts, Michigan, New York, North Carolina, Oregon, South Carolina, Tennessee
2021-12-21
Active, closed
A Study Evaluating the Efficacy and Safety of Mitapivat in Participants With Non-Transfusion-Dependent Alpha- or Beta-Thalassemia (α- or β-NTDT)
NCT04770753Non-Transfusion-dependent Alpha-Thalassemia, Non-Transfusion-dependent Beta-Thalassemia
DrugMitapivat
Agios Pharmaceuticals, Inc.
Phase 3
194
California, Massachusetts, New York, North Carolina, Pennsylvania
2021-12-20
Recruiting
ViTAA Medical Solutions
Observational
200
Alabama, Massachusetts, North Carolina, Washington
2021-12-15
Active, closed
Hologic, Inc.
Not applicable
7,500
Arizona, Florida, Kentucky, Maryland, Michigan, New York, North Carolina, Ohio
2021-12-10
Recruiting
Immunolight, LLC
Phase 1
52
District of Columbia, North Carolina, South Carolina
2021-12-08
Recruiting
H. Lundbeck A/S
Phase 3
600
Connecticut, Florida, Kentucky, Maryland, Michigan, New York, North Carolina, Ohio
2021-12-01
Active, closed
Agios Pharmaceuticals, Inc.
Phase 3
258
Arizona, California, Massachusetts, Michigan, New York, North Carolina, Pennsylvania, Washington
2021-11-30
Recruiting
Regeneron Pharmaceuticals
Phase 1/2
228
California, Connecticut, Kentucky, Maryland, New Jersey, New York, North Carolina, Ohio
2021-11-30
Recruiting
Pediatric Post-Approval Registry
NCT04457154Obstructive Sleep Apnea
Inspire Medical Systems, Inc.
Observational
60
Colorado, Georgia, North Carolina, Ohio, Pennsylvania, Texas, Virginia
2021-11-30
Active, closed
MRD Assay Evaluates Recurrence and Response Via a Tumor Informed Assessment
NCT05219734Cancer, Solid Tumor, Non Small Cell Lung Cancer, Colorectal Cancer
Invitae Corporation
Observational
400
Indiana, North Carolina
2021-11-29
Active, closed
Prospective Decision Impact Trial of KidneyIntelX
NCT04960514Diabetic Kidney Disease, Chronic Kidney Disease Stage 1, Chronic Kidney Disease Stage 2, Chronic Kidney Disease, Stage 3 (Moderate)
Renalytix AI, Inc.
Observational
2,000
North Carolina
2021-11-22
Recruiting
CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
NCT05143996Relapsed/Refractory Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)
DrugCLN-049
Cullinan Therapeutics Inc.
Phase 1
60
Alabama, California, Florida, Georgia, Massachusetts, New York, North Carolina, Ohio
2021-11-18
Recruiting
Ceribell Inc.
Observational
200
California, Florida, Iowa, Missouri, New Jersey, North Carolina, Pennsylvania
2021-11-10
Recruiting
ModernaTX, Inc.
Phase 1/2
50
California, Michigan, New York, North Carolina, Pennsylvania, Texas
2021-11-09
Recruiting
AbbVie
Phase 1
694
California, Illinois, Indiana, Kentucky, Michigan, Minnesota, Nebraska, North Carolina
2021-11-01
Active, closed
Cullinan Therapeutics Inc.
Phase 1
440
Alabama, California, Florida, Massachusetts, Michigan, New Jersey, New York, North Carolina
2021-10-29
Active, closed
Hoffmann-La Roche
Phase 3
478
California, Georgia, Indiana, Maryland, Michigan, Missouri, New York, North Carolina
2021-10-27
Active, closed
Pyrocarbon Clinical Follow-up Study
NCT05049993Osteoarthritis of the Shoulder, Avascular Necrosis, Traumatic Arthritis
Stryker Trauma and Extremities
Observational
76
Colorado, Florida, Louisiana, Maryland, Minnesota, Missouri, North Carolina, Oregon
2021-10-27
Active, closed
Hoffmann-La Roche
Phase 3
303
Alabama, Arkansas, California, Florida, Michigan, New York, North Carolina, Ohio
2021-10-26
Recruiting
argenx
Phase 2/3
12
Illinois, North Carolina, Virginia
2021-10-26
Active, closed
Valent Technologies, LLC
Phase 1
20
Arizona, California, District of Columbia, Georgia, Indiana, Missouri, North Carolina, Ohio
2021-10-25
Active, closed
Boehringer Ingelheim
Phase 1
151
Arizona, California, North Carolina, South Dakota, Texas
2021-10-18
Recruiting
AstraZeneca
Phase 1/2
460
California, Louisiana, Maryland, Massachusetts, Missouri, New Mexico, New York, North Carolina
2021-10-18
Active, closed
A Long-term Extension Study of Ustekinumab in Pediatric Participants
NCT05092269Crohn Disease, Colitis, Ulcerative, Arthritis, Psoriatic
DrugUstekinumab
Janssen Research & Development, LLC
Phase 3
159
Georgia, New York, North Carolina, Virginia
2021-10-18
By invitation
Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs
NCT04930289Interstitial Lung Disease, COPD, Cystic Fibrosis, Pulmonary Fibrosis
Paragonix Technologies
Observational
3,500
Arizona, California, Florida, Maryland, Massachusetts, New York, North Carolina, Pennsylvania
2021-10-15
Active, closed
TransMedics
Observational
166
Alabama, California, Georgia, Massachusetts, Michigan, Nebraska, North Carolina, Texas
2021-10-14
Active, closed
Study of Vimseltinib for Tenosynovial Giant Cell Tumor
NCT05059262Tenosynovial Giant Cell Tumor, Pigmented Villonodular Synovitis, Giant Cell Tumor of Tendon Sheath, Tenosynovial Giant Cell Tumor, Diffuse
DrugVimseltinib
Deciphera Pharmaceuticals, LLC
Phase 3
123
California, Colorado, Kansas, Massachusetts, Minnesota, New York, North Carolina, Ohio
2021-10-14
By invitation
SPI-1005 Treatment in Moderate COVID-19 Patients
NCT04484025Covid19, Corona Virus Infection, Coronavirus, Coronavirus Infection
DrugEbselen
Sound Pharmaceuticals, Incorporated
Phase 2
60
Connecticut, Idaho, Kansas, Missouri, North Carolina, Texas
2021-10-12
Active, closed
Hoffmann-La Roche
Phase 2
176
California, Missouri, North Carolina, Ohio, Oklahoma, Texas, Virginia, Washington
2021-10-07
Active, closed
A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP
NCT04971226Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive
DrugsBosutinib·Asciminib·ABL001·Nilotinib
Novartis Pharmaceuticals
Phase 3
405
Colorado, Florida, Kentucky, Massachusetts, North Carolina, Oregon, South Dakota, Tennessee
2021-10-06
Recruiting
A Study of NX-1607 in Adults With Advanced Malignancies
NCT05107674Ovarian Cancer, Epithelial, Gastric Cancer, GastroEsophageal Junction (GEJ) Cancer, Head and Neck Squamous Cell Carcinoma
DrugPaclitaxel
Nurix Therapeutics, Inc.
Phase 1
345
California, Colorado, Illinois, North Carolina, Oklahoma, Texas, Virginia, Washington
2021-09-29
Active, closed
SARS-CoV-2 Vaccine (GEO-CM04S1) Versus mRNA SARS-COV-2 Vaccine in Patients With Blood Cancer
NCT04977024COVID-19 Infection, Hematopoietic and Lymphoid System Neoplasm, Leukemia, Lymphoma
DrugCOVID-19 Vaccine
GeoVax, Inc.
Phase 2
63
California, Maryland, Massachusetts, New York, North Carolina, Washington
2021-09-27
Active, closed
Ultragenyx Pharmaceutical Inc
Phase 1/2
82
California, Illinois, Indiana, Massachusetts, Michigan, North Carolina, Ohio, Tennessee
2021-09-27
Recruiting
Trethera
Phase 1
94
California, North Carolina
2021-09-23
Recruiting
Pfizer
Observational
780
North Carolina
2021-09-23
Active, closed
Janssen Research & Development, LLC
Phase 1
166
Alabama, California, Colorado, Georgia, Indiana, New Jersey, New York, North Carolina
2021-09-22
Active, closed
Bristol-Myers Squibb
Phase 3
338
California, Colorado, Maryland, Minnesota, New Jersey, New York, North Carolina, Oregon
2021-09-15
Active, closed
Orthofix Inc.
Observational
2,000
California, Louisiana, Mississippi, North Carolina, Rhode Island, Utah, Virginia
2021-09-15
Recruiting
Helix Research Network
NCT06057181Genetic Predisposition to Disease, Genetics Disease
Helix, Inc
Observational
2,000,000
Indiana, Minnesota, Nebraska, Nevada, New York, North Carolina, Ohio, Pennsylvania
2021-09-13
Recruiting
Catapult Therapeutics
Phase 1
18
Massachusetts, North Carolina
2021-09-10
Recruiting
Zenith Epigenetics
Phase 2
200
California, Colorado, Florida, Louisiana, Maryland, Michigan, New York, North Carolina
2021-09-08
Active, closed
Vivet Therapeutics SAS
Phase 1/2
4
California, Connecticut, Florida, Michigan, North Carolina, Texas
2021-09-03
Active, closed
Albireo, an Ipsen Company
Phase 3
62
California, Georgia, Indiana, Maryland, Massachusetts, Missouri, New York, North Carolina
2021-09-03
Recruiting
Bempedoic Acid Pregnancy Surveillance Program
NCT05103254Pregnancy, Hyperlipidemias
DrugBempedoic acid
Esperion Therapeutics, Inc.
Observational
20
North Carolina
2021-09-01
Active, closed
Sanofi
Phase 3
17
California, Minnesota, New York, North Carolina, Ohio, Washington
2021-09-01
Active, closed
SkylineDx
Observational
1,820
Florida, Georgia, Kentucky, Michigan, Minnesota, New York, North Carolina, Utah
2021-08-25
Recruiting
WAKIX® (Pitolisant) Pregnancy Registry
NCT05536011Pregnancy Related, Narcolepsy
DrugPitolisant
Harmony Biosciences Management, Inc.
Observational
1,329
North Carolina
2021-08-24
Active, closed
HUYABIO International, LLC.
Phase 3
450
California, Florida, Indiana, Kentucky, Maryland, Missouri, Montana, North Carolina
2021-08-12
Active, closed
Tanabe Pharma America, Inc.
Phase 3
286
California, Florida, Massachusetts, Michigan, Missouri, New York, North Carolina, Ohio
2021-08-10
Active, closed
Cerus Endovascular, Inc.
Phase 4
250
Colorado, Florida, Illinois, Kansas, Massachusetts, New York, North Carolina, Pennsylvania
2021-08-06
By invitation
IT Matters: The Erectile Restoration Registry
NCT04200937Erectile Dysfunction
Boston Scientific Corporation
Observational
450
California, Florida, Illinois, Indiana, Louisiana, Missouri, North Carolina, Ohio
2021-08-05
Recruiting
GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors
NCT04977453Advanced Solid Tumor, Metastatic Solid Tumor, Cervical Cancer, Urothelial Carcinoma
DrugsLenvatinib·Keytruda·Pembrolizumab
GI Innovation, Inc.
Phase 1/2
317
New York, North Carolina
2021-08-02
Recruiting
Study to Evaluate Pregnancy Outcomes in Risankizumab Exposed Pregnancies Relative to Those Non-risankizumab Exposed Pregnancies in Women With FDA Approved Indications
NCT04846959Plaque Psoriasis, Psoriatic Arthritis, Crohn's Disease, or Other Conditions for Which Risankizumab is an FDA-approved Treatment
DrugsSkyrizi·Risankizumab
AbbVie
Observational
818
North Carolina
2021-07-30
Active, closed
EFS of the CardioMech MVRS
NCT04820764Mitral Regurgitation
CardioMech AS
Not applicable
35
California, Illinois, Kansas, Minnesota, New York, North Carolina, Ohio, Tennessee
2021-07-27
Active, closed
Presage Biosciences
Early Phase 1
15
Louisiana, New York, North Carolina, Ohio, Oregon, Pennsylvania, South Carolina, Washington
2021-07-26
Recruiting
Registry of Arthrex Hand and Wrist Products
NCT05046600Ulnar/Radial Collateral Ligament Reconstruction, Ligament Repair or Reconstruction, Small Bone Fragments and Arthrodesis, Scapholunate Ligament Reconstruction
Arthrex, Inc.
Observational
650
Arizona, Iowa, North Carolina, West Virginia
2021-07-20
Recruiting
Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.
NCT04775745CLL/SLL, Waldenstrom Macroglobulinemia, Follicular Lymphoma, Diffuse Large B Cell Lymphoma
DrugRocbrutinib
Newave Pharmaceutical Inc
Phase 1
60
North Carolina, Ohio, Utah
2021-07-19
Recruiting
Valved Graft PMCF Study
NCT04754217Aortic Valve Disease, Ascending Aorta Abnormality, Aortic Dissection
Abbott Medical Devices
Observational
260
Alabama, Michigan, North Carolina, Pennsylvania
2021-07-13
Active, closed
VectivBio AG
Phase 3
158
California, Florida, Illinois, Michigan, Minnesota, Nebraska, New York, North Carolina
2021-07-13
Active, closed
Bristol-Myers Squibb
Phase 2
74
Arizona, California, Connecticut, Florida, Michigan, Missouri, New York, North Carolina
2021-07-12
Active, closed
Ethicon, Inc.
Observational
198
North Carolina, Pennsylvania
2021-07-07
Active, closed
G7 Acetabular System With Vivacit-E or Longevity Liner PMCF Study
NCT04754087Total Hip Arthroplasty, Degenerative Joint Disease of Hip, Avascular Necrosis of Hip, Rheumatoid Arthritis of Hip
Zimmer Biomet
Not applicable
300
Colorado, Indiana, North Carolina, Oregon, Utah
2021-07-07
Active, closed
Boehringer Ingelheim
Phase 1
554
Alabama, California, District of Columbia, Florida, Georgia, Hawaii, New York, North Carolina
2021-07-02
Active, closed
Triathlon All-Polyethylene Tibia Outcomes Study
NCT04636190Arthropathy of Knee, Replacement, Knee Arthritis
Stryker Orthopaedics
Not applicable
204
Michigan, New York, North Carolina, Ohio, Texas
2021-07-02
Active, closed
Adrenas Therapeutics Inc
Phase 1/2
8
Illinois, Maryland, Minnesota, North Carolina, Pennsylvania
2021-07-01
Active, closed
InspireMD
Not applicable
317
Florida, Louisiana, Michigan, Missouri, New York, North Carolina, Ohio, Pennsylvania
2021-07-01
Recruiting
Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors
NCT04900818Solid Tumor, Advanced Cancer, Metastatic Cancer, Gastric Cancer
DrugGivastomig
I-Mab Biopharma US Limited
Phase 1
330
California, Colorado, Indiana, Massachusetts, New Jersey, New York, North Carolina, Tennessee
2021-06-29
Recruiting
Corcym S.r.l
Observational
2,150
Indiana, Louisiana, Maine, North Carolina, Ohio, Pennsylvania
2021-06-29
Recruiting
Hoffmann-La Roche
Phase 1/2
316
California, Massachusetts, New Jersey, North Carolina, Pennsylvania, Tennessee
2021-06-22
Active, closed
AstraZeneca
Phase 3
506
Massachusetts, North Carolina
2021-06-22
Active, closed
MIT-001 for Prevention of CCRT-Induced OM in HNSCC Patients
NCT04651634Head and Neck Squamous Cell Carcinoma, Oral Mucositis
DrugCCRT
MitoImmune Therapeutics
Phase 2
60
Arizona, California, Kansas, New York, North Carolina, Ohio
2021-06-21
Recruiting
ImmunoVaccine Technologies, Inc. (IMV Inc.)
Phase 2
102
California, Florida, Georgia, Indiana, Louisiana, Nebraska, New Mexico, North Carolina
2021-06-18
Active, closed
Novartis Pharmaceuticals
Phase 3
469
Colorado, Florida, Louisiana, Massachusetts, Missouri, Nebraska, New York, North Carolina
2021-06-15
Recruiting
Device Global Registry for the IlluminOss Bone Stabilization System
NCT05206981Traumatic Fracture, Pathological Fracture
IlluminOss Medical, Inc.
Observational
300
Alabama, California, Colorado, Florida, Indiana, New York, North Carolina, Pennsylvania
2021-06-11
Recruiting
Novartis Pharmaceuticals
Phase 4
130
Alabama, District of Columbia, Georgia, North Carolina, Pennsylvania, Texas
2021-06-10
Active, closed
NS Pharma, Inc.
Phase 4
9
California, Illinois, North Carolina, Virginia
2021-06-10
Active, closed
Sanofi
Observational
16
New York, North Carolina, Ohio, Tennessee, Washington
2021-06-10
Active, closed
Sanofi
Phase 2
129
Arizona, Florida, North Carolina, Wisconsin
2021-06-07
Active, closed
Persona Ti-Nidium Post-Market Clinical Follow-up
NCT04817969Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis
Zimmer Biomet
Not applicable
240
Colorado, Maryland, Mississippi, New Mexico, North Carolina, Pennsylvania, South Dakota
2021-06-01
Recruiting
Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care
NCT04299022Fractures, Bone, Nonunion of Fracture, Fractures, Open, Fractures, Ununited
LifeNet Health
Observational
250
Florida, New Jersey, North Carolina, Virginia
2021-06-01
Active, closed
Selective Internal Radiation Therapy (SIRT) Using SIR-Spheres® Y-90 Resin Microspheres on DoR & ORR in Unresectable Hepatocellular Carcinoma Patients
NCT04736121Unresectable Hepatocellular Carcinoma, BCLC Stage A Hepatocellular Carcinoma, BCLC Stage B Hepatocellular Carcinoma, BCLC Stage C Hepatocellular Carcinoma
Sirtex Medical
Not applicable
100
California, Florida, Georgia, Kansas, Massachusetts, New York, North Carolina, Ohio
2021-05-28
Active, closed
3Spine Lumbar Fusion Real World Evidence Study
NCT04823858Lumbar Spine Degeneration
3Spine
Observational
176
California, Colorado, Florida, Kentucky, Louisiana, Minnesota, New York, North Carolina
2021-05-25
Recruiting
Spectrum Pharmaceuticals, Inc
Phase 2
40
New York, North Carolina, Ohio, Texas
2021-05-20
Recruiting
GORE® ENFORM Biomaterial Product Study
NCT04718168Hernia, Ventral, Hernia, Hiatal, Hernia, Diaphragmatic, Incisional Hernia
W.L.Gore & Associates
Not applicable
245
California, Colorado, Florida, Illinois, Kentucky, North Carolina, South Carolina, Texas
2021-05-17
Active, closed
PTC Therapeutics
Phase 2
13
Massachusetts, North Carolina, Ohio, Texas
2021-05-12
Active, closed
Hoffmann-La Roche
Phase 3
1,188
Alabama, California, Florida, Georgia, Iowa, Maine, New Jersey, North Carolina
2021-05-04
Recruiting
Alnylam Pharmaceuticals
Observational
150
Alabama, Arizona, California, Maryland, Massachusetts, Minnesota, New York, North Carolina
2021-04-26
Active, closed
Novartis Pharmaceuticals
Phase 2
236
California, Colorado, Missouri, New York, North Carolina, Ohio, Pennsylvania, Texas
2021-04-19
Recruiting
ModernaTX, Inc.
Phase 1/2
77
California, Florida, Illinois, Maryland, Massachusetts, Michigan, New York, North Carolina
2021-04-15
Active, closed
Takeda
Phase 3
77
Georgia, New York, North Carolina, Ohio, Oklahoma
2021-04-14
Active, closed
Geron Corporation
Phase 3
327
California, Connecticut, Florida, Kentucky, New York, North Carolina, Ohio, South Dakota
2021-04-12
Active, closed
Kedrion S.p.A.
Phase 3
30
California, Colorado, Florida, Louisiana, North Carolina, Ohio, Oklahoma
2021-03-31
Recruiting
Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System
NCT04634916Kidney Disease, End-Stage, End-stage Renal Disease, Arteriovenous Fistula
C. R. Bard
Not applicable
220
California, Florida, Massachusetts, New York, North Carolina, Ohio, Pennsylvania, Tennessee
2021-03-26
Recruiting
Guerbet
Phase 4
2,076
Arizona, Connecticut, Illinois, Massachusetts, Missouri, North Carolina, Pennsylvania, Texas
2021-03-24
Active, closed
Bristol-Myers Squibb
Phase 1/2
216
California, Florida, Louisiana, Massachusetts, Michigan, New Jersey, North Carolina, Pennsylvania
2021-03-22
Active, closed
Atrasentan in Patients With Proteinuric Glomerular Diseases
NCT04573920IgA Nephropathy, Focal Segmental Glomerulosclerosis, Alport Syndrome, Diabetic Kidney Disease
DrugAtrasentan
Novartis Pharmaceuticals
Phase 2
103
California, Colorado, Louisiana, Massachusetts, Minnesota, Nevada, North Carolina, Texas
2021-03-15
Recruiting
UCB Biopharma SRL
Phase 3
70
New York, North Carolina
2021-03-11
Recruiting
Calico Life Sciences LLC
Phase 1
248
Arizona, Connecticut, Maryland, Massachusetts, Michigan, New York, North Carolina, Pennsylvania
2021-03-09
Active, closed
A Study of AZD0486 in Subjects With B-Cell Non-Hodgkin Lymphoma
NCT04594642B-cell Non Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, High-grade B-cell Lymphoma, Follicular Lymphoma
DrugSurovatamig
AstraZeneca
Phase 1
226
Florida, Kentucky, New Jersey, North Carolina, Ohio, Pennsylvania, Texas, Wisconsin
2021-03-02
Active, closed
AbbVie
Phase 1
81
Massachusetts, Missouri, North Carolina, Rhode Island, Texas, Virginia
2021-02-23
Recruiting
Single-Sided Deafness and Asymmetric Hearing Loss
NCT04506853Hearing Loss, Unilateral, Hearing Loss, Sensorineural
Med-El Corporation
Not applicable
65
Illinois, Iowa, New York, North Carolina, Washington
2021-02-22
Recruiting
PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches
NCT04545502Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection
Vascutek Ltd.
Observational
2,000
Colorado, Florida, Indiana, North Carolina, Ohio, Pennsylvania, Virginia
2021-02-17
By invitation
Sepsis Clinical Decision Support [CDS] Master Enrollment Study Protocol
NCT05304728Severe Sepsis, Severe Sepsis Without Septic Shock
Beckman Coulter, Inc.
Observational
40,000
California, Georgia, Indiana, Missouri, New Jersey, North Carolina, Ohio
2021-02-15
Active, closed
Boston Scientific Corporation
Not applicable
177
California, Colorado, Florida, Illinois, Indiana, Louisiana, New York, North Carolina
2021-02-10
Recruiting
Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study
NCT04761120Mitral Regurgitation, Tricuspid Regurgitation, Valvular Heart Disease
Abbott Medical Devices
Observational
550
North Carolina, Wisconsin
2021-02-01
Recruiting
Amgen
Observational
2,842
North Carolina
2021-01-27
By invitation
A Long-term Follow-up Study in Participants Who Received CTX001
NCT04208529Beta-Thalassemia, Thalassemia, Sickle Cell Disease, Hematologic Diseases
DrugExa-cel
Vertex Pharmaceuticals Incorporated
Phase 3
160
California, Illinois, New York, North Carolina, Pennsylvania, Tennessee, Texas
2021-01-20
Active, closed
Genmab
Phase 3
483
Indiana, Kentucky, Michigan, Minnesota, New Jersey, North Carolina, Ohio, Texas
2021-01-13
Recruiting
Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry
NCT04669548Intraabdominal Hypertension, Abdominal Compartment Syndrome, Acute Kidney Injury, Cardiovascular Surgery
Potrero Medical
Observational
2,500
California, District of Columbia, Florida, Kentucky, North Carolina, Ohio
2020-12-21
Active, closed
AstraZeneca
Phase 1
138
New York, North Carolina, Tennessee, Texas
2020-12-17
Active, closed
Janssen Research & Development, LLC
Phase 1/2
228
Alabama, Arkansas, Colorado, Georgia, Minnesota, Missouri, New York, North Carolina
2020-12-15
Active, closed
MeiraGTx Ocular UK Ltd
Phase 3
97
California, Florida, Georgia, Massachusetts, Michigan, North Carolina, Pennsylvania, Texas
2020-12-04
Active, closed
Daiichi Sankyo
Phase 3
1,600
California, Florida, Illinois, Kentucky, Louisiana, Maryland, New York, North Carolina
2020-12-04
Recruiting
Alnylam Pharmaceuticals
Observational
1,500
California, Florida, Iowa, Kansas, Maryland, Massachusetts, New York, North Carolina
2020-11-23
Recruiting
Sarepta Therapeutics, Inc.
Phase 1
83
Arkansas, California, Florida, Illinois, Missouri, North Carolina, Ohio, Texas
2020-11-23
By invitation
Adherus™ Dural Sealant in Spinal Procedures
NCT04498026Spinal Duraplasty
Stryker Craniomaxillofacial
Not applicable
114
California, Florida, Illinois, Minnesota, New York, North Carolina, Pennsylvania, Texas
2020-11-19
Active, closed
Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations
NCT04603001Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML), Myeloproliferative Neoplasms (MPNs)
DrugsLY3410738·Azacitidine·Venetoclax
Eli Lilly and Company
Phase 1
260
California, Florida, Illinois, Massachusetts, New York, North Carolina, Tennessee, Texas
2020-11-19
Active, closed
MeiraGTx, LLC
Observational
22
California, Massachusetts, North Carolina
2020-11-12
Active, closed
Pfizer
Phase 3
114
Arkansas, California, Florida, Iowa, Kansas, North Carolina, Pennsylvania, Utah
2020-11-05
Active, closed
Genmab
Phase 1/2
543
Alabama, California, Massachusetts, Michigan, New Jersey, New York, North Carolina, Texas
2020-11-03
Active, closed
The Synergy Disc To Anterior Cervical Discectomy and Fusion
NCT04469231Cervical Degenerative Disc Disease
Synergy Spine Solutions
Not applicable
175
Arizona, California, Colorado, Florida, Indiana, Michigan, New York, North Carolina
2020-10-30
Recruiting
A Study of Azenosertib (ZN-c3) in Patients With Ovarian Cancer
NCT04516447Solid Tumor, Epithelial Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
DrugsAzenosertib·Pegylated liposomal doxorubicin·Gemcitabine·Paclitaxel
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc
Phase 1
172
Colorado, Massachusetts, Missouri, New York, North Carolina, Rhode Island, Tennessee, Texas
2020-10-26
Active, closed
GID BIO, Inc.
Phase 3
114
California, Florida, Louisiana, New Jersey, North Carolina, Ohio, Pennsylvania, Texas
2020-10-15
Active, closed
Myasthenia Gravis Inebilizumab Trial
NCT04524273Myasthenia Gravis
DrugInebilizumab
Amgen
Phase 3
238
California, Connecticut, District of Columbia, Florida, Kansas, North Carolina, Ohio, Pennsylvania
2020-10-15
By invitation
Lumbar Interbody Implant Study
NCT04418830Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Scoliosis, Spinal Stenosis
NuVasive
Observational
1,050
California, Connecticut, Florida, Illinois, Michigan, Missouri, North Carolina, Ohio
2020-10-01
Active, closed
Hoffmann-La Roche
Phase 3
190
North Carolina, Ohio
2020-09-30
Recruiting
Cabaletta Bio
Phase 1/2
40
California, Connecticut, Illinois, Iowa, Massachusetts, New York, North Carolina, Pennsylvania
2020-09-29
Active, closed
Janssen Research & Development, LLC
Phase 2
194
Alabama, California, Georgia, Michigan, New York, North Carolina, Pennsylvania
2020-09-17
Active, closed
Seagen, a wholly owned subsidiary of Pfizer
Phase 2
40
Arizona, Colorado, District of Columbia, Missouri, New Mexico, North Carolina, Ohio, Washington
2020-09-15
Active, closed
Medaxis, LLC
Not applicable
222
California, Florida, Maryland, North Carolina, Ohio, Virginia
2020-09-11
Active, closed
Razor Genomics
Not applicable
420
California, Florida, Kentucky, Missouri, New Jersey, North Carolina, Oklahoma, Pennsylvania
2020-09-11
Active, closed
Hoffmann-La Roche
Phase 1/2
210
Arizona, California, Massachusetts, Michigan, North Carolina, Texas
2020-09-03
Active, closed
A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors
NCT04482309Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer, Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer
DrugTrastuzumab deruxtecan
AstraZeneca
Phase 2
477
California, Illinois, Indiana, Massachusetts, New Jersey, New York, North Carolina, Texas
2020-08-18
Active, closed
Hoffmann-La Roche
Phase 1/2
237
California, Florida, Kentucky, Louisiana, Michigan, North Carolina, Ohio, Rhode Island
2020-08-12
Active, closed
Safety and Effectiveness Study of OR3O™ Dual Mobility System in THA
NCT04325022Advanced Degeneration of the Hip Joint, Revision of the Hip Joint
Smith & Nephew, Inc.
Observational
177
Kentucky, Nebraska, New York, North Carolina, Texas
2020-07-27
Active, closed
AstraZeneca
Phase 3
134
California, Georgia, Maryland, Michigan, North Carolina, Ohio, Utah
2020-07-20
Active, closed
Denali Therapeutics Inc.
Phase 1/2
47
California, Illinois, North Carolina, Pennsylvania
2020-07-16
Active, closed
GlaxoSmithKline
Phase 3
242
California, Florida, Michigan, New York, North Carolina, Pennsylvania, Texas, Washington
2020-07-14
By invitation
Cervical Interbody Implant Study
NCT04689854Degenerative Disc Disease, Cervical Spinal Instability
NuVasive
Observational
150
California, Connecticut, Massachusetts, Missouri, North Carolina, Ohio, Virginia
2020-07-07
Active, closed
A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors
NCT04478279Glioblastoma, Melanoma Stage IV, Breast Cancer, Prostate Cancer
DrugTemozolomide
Sapience Therapeutics
Phase 1/2
125
California, Colorado, Illinois, Michigan, New York, North Carolina, Tennessee
2020-07-01
Active, closed
Sanofi
Phase 3
337
California, Colorado, Florida, Massachusetts, North Carolina, Tennessee, Texas
2020-06-16
Active, closed
4D-125 in Patients With X-Linked Retinitis Pigmentosa (XLRP)
NCT04517149X-Linked Retinitis Pigmentosa
4D Molecular Therapeutics
Phase 1/2
21
Colorado, Florida, Michigan, New York, North Carolina, Oregon, Texas, Utah
2020-06-09
Recruiting
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
NCT04429542Head and Neck Squamous Cell Carcinoma, Squamous Cell Carcinoma of Anal Canal, Colorectal Cancer, Squamous Cell Carcinoma of the Lung
DrugPembrolizumab
Bicara Therapeutics
Phase 1
473
California, Florida, Massachusetts, New York, North Carolina, Ohio, Pennsylvania, Rhode Island
2020-06-01
Active, closed
A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors
NCT04396821Advanced Cancer, Gastric Cancer, Gastroesophageal-junction Cancer, Pancreatic Cancer
DrugsTST001·MFOLFOX6·Albumin-Bound Paclitaxel·Opdivo
Transcenta Therapeutics (Hangzhou) Co., Ltd.
Phase 1/2
150
Arizona, Connecticut, Florida, Georgia, Kansas, Missouri, New York, North Carolina
2020-05-28
Active, closed
MediciNova
Phase 2/3
234
California, Florida, Georgia, Indiana, Maryland, Minnesota, New York, North Carolina
2020-05-28
Recruiting
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
NCT04256317Myelodysplastic Syndromes, Acute Myeloid Leukemia, Myelodysplastic Syndrome/Neoplasm, Chronic Myelomonocytic Leukemia
DrugsVenclexta·Azacitidine·Venetoclax
Taiho Oncology, Inc.
Phase 2/3
316
California, Connecticut, Florida, Georgia, Massachusetts, New Jersey, New York, North Carolina
2020-05-21
Recruiting
CERAMENT™| Bone Void Filler Device Registry
NCT04244942Orthopedic Disorder
BONESUPPORT AB
Observational
300
Arizona, Florida, Indiana, Kentucky, Massachusetts, New York, North Carolina, Ohio
2020-03-30
Recruiting
Ascentage Pharma Group Inc.
Phase 1
144
California, Florida, Massachusetts, North Carolina, Ohio, Washington
2020-03-02
Active, closed
Janssen Research & Development, LLC
Phase 1
290
California, New York, North Carolina, Pennsylvania, Tennessee, Wisconsin
2020-02-21
Active, closed
Genetix Biotherapeutics Inc.
Phase 3
35
Alabama, District of Columbia, Massachusetts, Minnesota, New Jersey, New York, North Carolina, Texas
2020-02-14
Active, closed
Amicus Therapeutics
Phase 3
21
Florida, Georgia, Missouri, North Carolina, Ohio, Pennsylvania, Utah, Virginia
2020-02-13
Active, closed
Hoffmann-La Roche
Phase 2/3
325
California, Massachusetts, New York, North Carolina, Tennessee, Texas, Washington
2020-01-29
Recruiting
Kaneka Medical America LLC
Not applicable
35
California, Delaware, Michigan, New York, North Carolina, Ohio, South Carolina, Virginia
2020-01-01
Active, closed
GlaxoSmithKline
Phase 1
118
Kansas, North Carolina, Wisconsin
2019-12-18
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Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 12 October 2026. https://priyalifescience.com/clinical-trials-usa/state/north-carolina?page=2

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,132 studies in total at the last sync on 11 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 1,082 of those studies with a site in North Carolina.

How many clinical trials are recruiting in North Carolina?

595 of the 1,082 studies on this page are recruiting new participants as of the 11 Oct 2026, 03:16 UTC sync. A further 28 have not yet opened recruitment, 411 are active but closed to new participants, and 48 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.