Clinical Trials in Monterrey, 2026

AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications

Eli Lilly and Company

Phase 3

150

Guadalajara, León, Monterrey, Querétaro

2026-09-25

Recruiting

FIBRONEER-ACT: A Study to Test Whether Nerandomilast Helps People With Fibrosing Interstitial Lung Disease at Risk for Disease Progression

NCT07540988Interstitial Lung Diseases

DrugNerandomilast

Boehringer Ingelheim

Phase 3

466

Chihuahua City, León, Monterrey

2026-09-17

Recruiting

A Study to Evaluate the Efficacy of VVD-133214 in Combination With Pembrolizumab Compared With Pembrolizumab Alone in Participants With Advanced Cancer of the Colon or Rectum

NCT07811193Colorectal Adenocarcinoma

DrugsVVD-133214·Pembrolizumab

Vividion Therapeutics, Inc.

Phase 2

140

Guadalajara, Benito Juárez, Mexico City, Monterrey

2026-09-11

Recruiting

A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

NCT07623161Myelofibrosis, Anemia

DrugElritercept

Takeda

Phase 3

324

Huixquilucan, Monterrey, Oaxaca City

2026-09-10

Not yet open

BALANCE-DM2 Study of Bofanglutide in Adults With Type 2 Diabetes

NCT07628985Type 2 Diabetes Mellitus (T2DM)

DrugsBofanglutida·Semaglutide

Carnot Laboratories

Phase 3

374

Mexico City, Pachuca, Guadalajara, Monterrey, Oaxaca City

2026-09

Not yet open

Meniscal Repair Augmented With Leukocyte-Poor Platelet-Rich Plasma: A Prospective Comparative Clinical Study

NCT07815743Meniscal Tears

DrugLeukocyte-Poor Platelet-Rich Plasma

Universidad Autonoma de Nuevo Leon

Not applicable

Monterrey

2026-09

Active, closed

Pilot Trial of the Body Image Program to Prevent Eating Disorders in Female University Students in Mexico

NCT07193043Eating Disorders, Body Dissatisfaction

Comenzar de Nuevo, AC

Not applicable

Monterrey

2026-08-26

Recruiting

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

NCT07794579Overweight, Prediabetic State, Prehypertension, Obesity, Abdominal

DrugOrforglipron

Eli Lilly and Company

Phase 3

2,001

Ciudad Madero, Culiacán, Guadalajara, Mexico City, Mérida, Monterrey, San Nicolás de los Garza, Tlalpan

2026-08-26

Recruiting

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

NCT07761117Heart Failure With Preserved Ejection Fraction (HFpEF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)

DrugElecoglipron

AstraZeneca

Phase 3

6,950

Guadalajara, México, Monterrey, Querétaro, San Luis Potosí City, Tijuana, Xalapa, Zapopan

2026-08-24

Recruiting

NCT07797335Type 2 Diabetes, Cardiovascular Risk

DrugZenagamtide

Novo Nordisk A/S

Phase 3

1,778

Guadalajara, Tlalpan, Monterrey, Hermosillo, Ciudad Madero, Merida Centro, Mérida

2026-08-24

Recruiting

A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.

NCT07753993Chronic Kidney Disease

DrugElecoglipron

AstraZeneca

Phase 3

7,000

Chihuahua City, Culiacán, Mazatlán, Mérida, Monterrey, Zapopan

2026-08-21

Recruiting

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes

NCT07282613Diabetes Mellitus, Type 2

DrugCagriSema

Novo Nordisk A/S

Phase 3

Coyoacán, Monterrey, San Nicolás de los Garza, Cuauhtémoc, Puebla City

2026-08-04

Recruiting

A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes

NCT07668336Diabetes Mellitus, Type 2

DrugsDulaglutide·Orforglipron

Eli Lilly and Company

Phase 3

170

Ciudad Madero, Guadalajara, Monterrey

2026-07-08

Recruiting

A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus

NCT07662109Type 2 Diabetes Mellitus

DrugsElecoglipron·Dapagliflozin

AstraZeneca

Phase 3

2,000

Cuernavaca, Guadalajara, Monterrey, San Luis Potosí City, Zapopan

2026-07-06

Recruiting

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin

NCT07662135Type 2 Diabetes Mellitus, Type 2 Diabetes With Chronic Kidney Disease

DrugElecoglipron

AstraZeneca

Phase 3

900

Chihuahua City, Cuernavaca, Guadalajara, Mexico City, Monterrey, Zapopan

2026-07-06

Recruiting

A Phase IIb Study to Evaluate AZD8965 in Participants With IPF.

NCT07652658Idiopathic Pulmonary Fibrosis (IPF)

AstraZeneca

Phase 2

359

Benito Juárez, Chihuahua City, Coyocan, León, Mérida, Monterrey, Oaxaca City, Pachuca

2026-06-11

Recruiting

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

NCT07595549Obesity, Overweight and/or Obesity, Overweight

DrugBerobenatide

Pfizer

Phase 3

954

Mexico City, Cuernavaca, Monterrey

2026-06-10

Recruiting

The FILTRATE Trial: High-Rate Ultrafiltration for Intravascular Congestion

NCT07705269End Stage Chronic Renal Failure, Congestive Heart Failure (CHF), Intravascular Congestion, Fluid Overload

Universidad Autonoma de Nuevo Leon

Not applicable

Monterrey

2026-06-04

Recruiting

An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED

NCT07519902Persistent Corneal Epithelial Defect

DrugCenegermin

Dompé Farmaceutici S.p.A

Phase 3

150

Col. Buenos Aires NorteTijuana, Mexico City, Monterrey, Mexico

2026-06-02

By invitation

Real World Outcomes of Intranasal MuSE Exosomes and Stem Cells in Neurological Regenerative Therapy

NCT07521384Traumatic Brain Injury, Cerebral Palsy, Hypoxic Ischemic Encephalopathy, Neurologic Disorders

Healing Hope International

Observational

Monterrey

2026-06-01

Recruiting

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

NCT07192952Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric)

DrugFinerenone

Bayer

Phase 3

117

Guadalajara, México D.F., Tlalpan, Monterrey, Huixquilucan, Ciudad Madero, Querétaro, San Luis Potosí City

2026-06-01

By invitation

Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)

NCT07511660Perimenopause, Perimenopause-Related Depression, Premature Ovarian Insufficiency, Premature Ovarian Failure (POF)

Healing Hope International

Observational

Monterrey

2026-06-01

Recruiting

A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Lower Risk Myelodysplastic Syndromes (LR-MDS) Who Need Regular Blood Transfusions

NCT07422480Myelodysplastic Syndrome, Anemia

DrugsElritercept·Epoetin Alfa

Takeda

Phase 3

300

Morelia, Monterrey, Mexico City, Oaxaca City

2026-05-21

Active, closed

AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

NCT07400107Obesity, Overweight, Diabetes Mellitus, Type 2

DrugsNNC0487-0111·Semaglutide

Novo Nordisk A/S

Phase 3

985

Guadalajara, Monterrey, Ciudad Madero

2026-05-20

Recruiting

A Study to Evaluate the Efficacy and Safety of TP-06 for PCED

NCT07886268Persistent Corneal Epithelial Defect

Tarsus Pharmaceuticals, Inc.

Phase 2

Mexico City, Monterrey

2026-04-20

Recruiting

DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy

NCT07472517Small Cell Lung Cancer (SCLC), Extensive-stage Small Cell Lung Cancer (ES-SCLC)

DrugsObrixtamig·Etoposide·Atezolizumab·Carboplatin

Boehringer Ingelheim

Phase 3

670

Guadalajara, Jalisco, Mexico City, México, Monterrey, Nuevo León, Toluca

2026-04-13

Recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

NCT07293351Advanced Renal Cell Carcinoma (RCC)

DrugsCasdatifan·Pumitamig·Cabozantinib·Yervoy

Bristol-Myers Squibb

Phase 1/2

474

Monterrey, Oaxaca City, Puebla City, Tlalpan

2026-03-26

Recruiting

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

NCT07415044Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate, Ulcerative Colitis, Active Severe

DrugZotemtegrast

Eli Lilly and Company

Phase 2

1,431

Chihuahua City, Ciudad de Tijuana, Guadalajara, Irapuato, Mexico City, Monterrey, Querétaro

2026-03-26

Recruiting

PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease

NCT07355296Proteinuric Kidney Diseases

DrugApecotrep

Boehringer Ingelheim

Phase 2

132

Aguascalientes, Mexico City, Monterrey, Tlalpan

2026-03-23

Recruiting

Low Dose Epcoritamab Plus GemOx in R/R DLBCL

NCT07451652Relapsed/Refractory Diffuse Large B Cell Lymphoma

DrugsEpcoritamab·Oxaliplatin·Gemcitabine

Hospital Universitario Dr. Jose E. Gonzalez

Phase 2

Monterrey

2026-03-17

Recruiting

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

NCT07361497Non-small Cell Lung Cancer (NSCLC)

DrugsPumitamig·Durvalumab

Bristol-Myers Squibb

Phase 3

850

Saltillo, Tijuana, Zapopan, Monterrey, Puebla City, Querétaro

2026-03-16

Recruiting

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

NCT07361510Non-Small Cell Lung Cancer (NSCLC)

DrugsPumitamig·Pembrolizumab

Bristol-Myers Squibb

Phase 3

750

Guadalajara, Zapopan, Mexico City, Monterrey, Oaxaca City, Puebla City, Querétaro

2026-03-12

Recruiting

Epidemiology and Processes of Care for Renal Replacement Therapy in Acute Kidney Injury in Latin America

NCT07262320Dialysis, Critically Ill Acute Kidney Injury, Renal Replacement Therapy for Acute Kidney Injury in ICU, Acute Kidney Injury

University of Alabama at Birmingham

Observational

1,000

Guadalajara, Mexico City, Monterrey

2026-03-01

By invitation

Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)

NCT07264166Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn

Healing Hope International

Observational

Monterrey

2026-03-01

Recruiting

A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)

NCT07220083Focal Segmental Glomerulosclerosis

DrugApecotrep

Boehringer Ingelheim

Phase 3

286

Aguascalientes, Mexico City, Monterrey

2026-02-16

Recruiting

Losartan for Corneal Fibrosis

NCT07449000Corneal Scarring Fibrosis

DrugLosartan

Universidad Autonoma de Nuevo Leon

Not applicable

Monterrey

2026-02-12

Recruiting

Upper Punctal Plug Occlusion in Previous Lower Punctal Occlusion.

NCT07571330DED, Aqueous-deficient Dry Eye Disease

Universidad Autonoma de Nuevo Leon

Not applicable

Monterrey

2026-02-12

Recruiting

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

NCT07392190Overweight, Obesity

DrugEloralintide

Eli Lilly and Company

Phase 3

900

Chihuahua City, Guadalajara, Huixquilucan, Mexicali, Mexico City, Monterrey

2026-02-10

Recruiting

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

NCT07216703Cervical Cancer

DrugsMvasi·Paraplatin·Sacituzumab tirumotecan·Avastin

Merck Sharp & Dohme LLC

Phase 3

1,023

Guadalajara, Benito Juárez, Mexico City, Monterrey, Chihuahua City, Oaxaca City

2026-01-19

Recruiting

Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations

NCT07195695Non-small Cell Lung Cancer

DrugsZongertinib·Atezolizumab·Durvalumab·Nivolumab

Boehringer Ingelheim

Phase 3

400

Jalisco, Mexico City, México, Monterrey

2026-01-16

Recruiting

Effects of Semaglutide on Clinical Outcomes and Metabolic Inflammation in Psoriasis

NCT07401992Psoriasis (PsO), Obesity & Overweight, Diabetes Mellitus - Type 2

A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Hospital Universitario Dr. Jose E. Gonzalez

Phase 4

Monterrey

2026-01-15

Recruiting

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

NCT07253285Overweight, Obesity

DrugsCagrilintide·Semaglutide

Novo Nordisk A/S

Phase 3

460

Monterrey, Puebla City

2026-01-08

Recruiting

Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

NCT07179380Pulmonary Hypertension, Interstitial Lung Disease

DrugTreprostinil Palmitil

Insmed Incorporated

Phase 3

344

Monterrey, Mexico City

2026-01-07

Recruiting

NCT07063745Metastatic Non-small Cell Lung Cancer With MTAP Deletion

DrugsNavlimetostat·Nab-paclitaxel·Pemetrexed·Paclitaxel

Bristol-Myers Squibb

Phase 2/3

590

Tijuana, Guadalajara, Zapopan, Mexico City, Monterrey, Oaxaca City, Chihuahua City, Puebla City

2026-01-02

Recruiting

Assess Accuracy of Primary Care Asthma and COPD Diagnosis Using Oscillometry and FeNO vs Specialist Diagnosis

NCT07245576Asthma, COPD

AstraZeneca

Observational

600

Monterrey, Santiago de Quer Taro

2025-12-26

Recruiting

A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

NCT07276581Rheumatoid Arthritis

AstraZeneca

Phase 2

320

Chihuahua City, Estado de México, Guadalajara, Gustavo A. Madero, Mexicali, Mexico City, Mérida, Monterrey

2025-12-15

Recruiting

Study of Clinical and Patient-reported Outcomes in Adults With Moderate to Severe COPD Treated With Breztri/Trixeo

NCT07069829Chronic Obstructive Pulmonary Disease

AstraZeneca

Observational

1,400

Guadalajara, Mexico City, Monterrey

2025-12-15

Recruiting

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

NCT07282600Overweight, Obesity

DrugEloralintide

Eli Lilly and Company

Phase 3

1,035

Guadalajara, Mérida, Monterrey

2025-12-15

Recruiting

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

NCT06979453Plaque Psoriasis

DrugDeucravacitinib

Bristol-Myers Squibb

Phase 3

366

Zapopan, Mexico City, Monterrey, Chihuahua City, Mérida, Toluca, Veracruz

2025-12-03

Recruiting

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

NCT06937229Alzheimer Disease, Agitation

DrugsKarX-EC·KarXT

Bristol-Myers Squibb

Phase 3

650

Saltillo, Guadalajara, Mexico City, Monterrey, San Luis Potosí City, Tlalnepantla

2025-12-02

Recruiting

A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema

NCT06807281Atopic Dermatitis

DrugAbrocitinib

Pfizer

Phase 3

450

Mexico City, Monterrey, Veracruz, Chihuahua City

2025-12-02

Recruiting

A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

NCT07227402Renal Cell Carcinoma

DrugsZanzalintinib·Belzutifan·Cabozantinib

Merck Sharp & Dohme LLC

Phase 3

904

Guadalajara, Monterrey, Oaxaca City, Mexico City, Puebla City

2025-11-26

Recruiting

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

NCT07188805Left Ventricular Systolic Dysfunction, Heart Failure (Pediatric)

DrugFinerenone

Bayer

Phase 3

111

Guadalajara, Mexico City, Monterrey, Querétaro City, San Luis Potosí City, Huixquilucan, Ciudad Madero, Tlalpan

2025-11-19

Recruiting

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

NCT07228832Metastatic Colorectal Cancer (CRC)

DrugsIvonescimab·Leucovorin·Adrucil·Oxaliplatin

Summit Therapeutics

Phase 3

900

Aguas Calientes, Mexico City, Monterrey, Oaxaca City

2025-11-18

Active, closed

A Study of Zasocitinib in Adults With Nonsegmental Vitiligo

NCT07108283Nonsegmental Vitiligo

DrugZasocitinib

Takeda

Phase 2

207

Monterrey, Morelia, Veracruz

2025-11-03

Recruiting

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

NCT07173751Breast Neoplasms

DrugsEribulin·Pumitamig·Gemcitabine·Carboplatin

BioNTech SE

Phase 3

558

Aguascalientes, León, Mexico City, Monterrey, San Luis Potosí City, Zapopan

2025-10-30

Active, closed

A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)

NCT07076121Pancreatic Ductal Adenocarcinoma

DrugsNavlimetostat·Abraxane·Nab-paclitaxel·Gemcitabine

Bristol-Myers Squibb

Phase 2/3

470

Zapopan, Cuauhtémoc, Ciudad de México, Mexico City, Monterrey, Oaxaca City, Mérida, Puebla City, Querétaro

2025-10-23

Recruiting

A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)

NCT07165028Metabolic Dysfunction-Associated Steatotic Liver Disease

DrugsRetatrutide·Tirzepatide

Eli Lilly and Company

Phase 3

4,500

Chihuahua City, Cuauhtémoc, Cuernavaca, Guadalajara, Metepec, Mexico City, Mérida, Monterrey

2025-10-15

Recruiting

Anti-Inflammatory Effects of Pecan Nut Oil Supplementation in Adults With Overweight: A Randomized Controlled Parallel-Group Clinical Trial

NCT07497555Overweight (BMI > 25)

Universidad Autonoma de Nuevo Leon

Not applicable

Monterrey

2025-10-15

Recruiting

A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

NCT07190248Non-small Cell Lung Cancer

Drugs) Berahyaluronidase alfa·Calderasib·Platinol-AQ·Paraplatin

Merck Sharp & Dohme LLC

Phase 3

675

Guadalajara, Benito Juárez, Monterrey, Oaxaca City, Chihuahua City, Mexico City, Puebla City

2025-10-08

Recruiting

Probiotic and Prebiotic Supplementation in Peritoneal Dialysis Patients

NCT07694791Chronic Kidney Disease (Stages 4 and 5), Peritoneal Dialysis (PD)

Hospital Universitario Dr. Jose E. Gonzalez

Not applicable

Monterrey

2025-10-03

Recruiting

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

NCT07184931Crohn's Disease

DrugDuvakitug

Sanofi

Phase 3

980

Monterrey, Jalisco, Veracruz

2025-10-01

Recruiting

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

NCT07202884Urinary Incontinence,Stress

DrugOrforglipron

Eli Lilly and Company

Phase 3

1,000

Chihuahua City, Ciudad Madero, Juriquilla, Mexico City, Mérida, México, Monterrey, Morelia

2025-09-30

Recruiting

Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

NCT07116967Plaque Psoriasis

DrugsUstekinumab·Deucravacitinib

Bristol-Myers Squibb

Phase 3

3,040

Mexicali, Guadalajara, Zapopan, Monterrey, Mérida, Chihuahua City, Mexico City

2025-09-22

Recruiting

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

NCT07190209Chronic Obstructive Pulmonary Disease

DrugLunsekimig

Sanofi

Phase 3

942

Monterrey, San Juan del Río, Durango, Mexico City, Veracruz

2025-09-16

Active, closed

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

NCT07153471Osteoarthritis

DrugOrforglipron

Eli Lilly and Company

Phase 3

800

Chihuahua City, Ciudad Madero, Mexicali, Mérida, Monterrey

2025-09-15

Active, closed

A Study to Test Whether Nerandomilast Helps People With Lung Fibrosis Related to Rheumatic Diseases

NCT06806592Interstitial Lung Diseases, Systemic Autoimmune Rheumatic Diseases Associated Interstitial Lung Diseases

DrugNerandomilast

Boehringer Ingelheim

Phase 3

414

Chihuahua City, Guadalajara, Mexico City, Mérida, Monterrey

2025-09-13

Recruiting

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

NCT06926868Breast Neoplasms

DrugsIza-bren·Nab-paclitaxel·Capecitabine·Gemcitabine

Bristol-Myers Squibb

Phase 2/3

600

Mexico City, Tijuana, Guadalajara, Monterrey, Oaxaca City, Mérida, Chihuahua City

2025-09-11

Recruiting

A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

NCT06973187Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma

DrugsTacabrutideg·Pirtobrutinib

BeOne Medicines

Phase 3

500

México, Monterrey, Oaxaca City, Toluca

2025-09-04

Recruiting

BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

NCT07160244Healthy

Drug20-valent pneumococcal conjugate vaccine

Pfizer

Phase 3

6,000

Guadalajara, Mexico City, Morelia, Monterrey, San Juan del Río, Veracruz

2025-08-25

Recruiting

A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)

NCT07058077Heterozygous Familial Hypercholesterolemia (HeFH)

DrugsEnlicitide·Enlicitide Decanoate

Merck Sharp & Dohme LLC

Phase 2/3

153

Monterrey, Oaxaca City, Huixquilucan

2025-08-21

Recruiting

Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.

NCT06858319Kidney Diseases, Kidney Diseases, Chronic, Urological Diseases, Glomerulonephritis

DrugZigakibart

Novartis Pharmaceuticals

Phase 3

220

Monterrey

2025-07-28

Active, closed

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

NCT07037433Atherosclerotic Cardiovascular Disease, Overweight, Obesity

DrugMaridebart cafraglutide

Amgen

Phase 3

12,800

Guadalajara, Mexico City, Cuernavaca, Monterrey, Culiacán, Tampico, Mérida, Cuauhtémoc

2025-07-25

Recruiting

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

NCT06757634Breast Cancer

DrugsGedatolisib·Ribociclib·Palbociclib·Letrozole

Celcuity Inc

Phase 3

1,180

Aguascalientes, Guadalajara, Mexico City, Monterrey, Morelia

2025-07-24

Recruiting

A Study of the Medicine Called Abrocitinib in Children 6 to Less Than 12 Years of Age With Moderate-to-Severe Eczema

NCT06807268Eczema

DrugAbrocitinib

Pfizer

Phase 3

150

Mexico City, Monterrey, Veracruz, Chihuahua City

2025-07-24

Recruiting

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

NCT07064473Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases

A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

Boehringer Ingelheim

Phase 3

11,800

Chihuahua City, Cuernavaca, Culiacán, Guadalajara, Mexico City, Mérida, México, Monterrey

2025-07-22

Recruiting

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

NCT07060807Breast Neoplasms

DrugsPatritumab deruxtecan·Pegylated liposomal doxorubicin·Abraxane·Xeloda

Merck Sharp & Dohme LLC

Phase 3

1,000

Guadalajara, Monterrey, Querétaro City, Chihuahua City, Oaxaca City

2025-07-21

Recruiting

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

NCT06765109Non-small Cell Lung Cancer, Anaplastic Lymphoma Kinase-positive

DrugsNeladalkib·Alectinib

Nuvalent Inc.

Phase 3

450

Mexico City, Monterrey, Morelia, Naucalpan

2025-07-17

Recruiting

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

NCT06997497Colon Adenocarcinoma, Rectal Adenocarcinoma

DrugsLeucovorin/levofolinate calcium·Bevacizumab biosimilar·Calderasib·Mvasi

Merck Sharp & Dohme LLC

Phase 3

477

Guadalajara, Mexico City, Monterrey, San Pedro Garza García, Aguascalientes, Oaxaca City

2025-07-16

Recruiting

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

NCT07011732Alzheimer Disease

DrugsKarX-EC·KarXT

Bristol-Myers Squibb

Phase 3

426

Saltillo, Guadalajara, Mexico City, Monterrey, San Luis Potosí City, Tlalnepantla

2025-07-10

Recruiting

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)

NCT07082725Niemann-Pick Type C Disease

DrugNizubaglustat

Azafaros B.V.

Phase 3

Monterrey, Aguascalientes

2025-06-30

Recruiting

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

NCT07054515Niemann-Pick Type C Disease, GM1 Gangliosidosis, GM2 Gangliosidosis

DrugNizubaglustat

Azafaros B.V.

Phase 3

147

Monterrey, Aguascalientes

2025-06-30

Recruiting

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

NCT07082738Chronic Obstructive Pulmonary Disease (COPD)

AstraZeneca

Phase 2

987

Chihuahua City, Durango, Guadalajara, Mexico City, Monterrey

2025-06-27

Recruiting

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

NCT07037459Heart Failure With Preserved Ejection Fraction, Heart Failure With Mildly Reduced Ejection Fraction, Obesity

DrugMaridebart cafraglutide

Amgen

Phase 3

5,056

Mexico City, Monterrey, Juriquilla, Querétaro City, Culiacán, Aguascalientes

2025-06-25

Recruiting

NCT06952504Endometrial Cancer

DrugsSacituzumab tirumotecan·Keytruda·Docetaxel·Paclitaxel

Merck Sharp & Dohme LLC

Phase 3

1,123

Guadalajara, Monterrey, Oaxaca City, Aguascalientes, Chihuahua City

2025-05-22

Recruiting

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

NCT06935370Heart Failure

Boehringer Ingelheim

Phase 3

4,200

Aguascalientes, Culiacán, Guadalajara, Irapuato, México, Monterrey, Querétaro, Tijuana

2025-05-20

Recruiting

Phase III Extension Study of Efficacy and Safety of Ianalumab With or Without Study Treatment Withdrawal in Participants With Lupus Nephritis (SIRIUS-LN Extension)

NCT06711887Lupus Nephritis

DrugIanalumab

Novartis Pharmaceuticals

Phase 3

348

León, Monterrey, Oaxaca City, Querétaro

2025-05-19

Recruiting

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

NCT06925737Prostate Cancer, Prostatic Neoplasms

DrugsIfinatamab Deruxtecan·Prednisolone·Prednisone·Docetaxel

Merck Sharp & Dohme LLC

Phase 3

1,440

Pachuca, Guadalajara, Mexico City, Monterrey, Oaxaca City

2025-05-13

Active, closed

A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight

NCT06962280Type 1 Diabetes, Obesity, Overweight

Eli Lilly and Company

Phase 3

465

Chihuahua City, Guadalajara, Mexico City, Monterrey, Puebla City, Tampico

2025-05-12

Active, closed

Effectiveness and Acceptability of LISEFEX® (Liposomal Iron With Vitamin C and Fiber) in People With Iron Deficiency Anemia.

NCT07483645Iron Deficiency Anemia

Carnot Laboratories

Observational

Monterrey

2025-05-06

Active, closed

A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight

NCT06914895Type 1 Diabetes, Obesity, Overweight

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

Eli Lilly and Company

Phase 3

905

Chihuahua City, Guadalajara, Hacienda de Las Palmas, Monterrey, Puebla City, Tampico

2025-04-25

Recruiting

NCT06875310Carcinoma, Non-Small-Cell Lung

DrugsAdagrasib·Pemetrexed·Keytruda·Cisplatin

Mirati Therapeutics Inc.

Phase 3

630

Saltillo, Mexico City, Pachuca, Guadalajara, Monterrey, Puebla City, Veracruz

2025-04-24

Active, closed

Extension Study of Sotatercept in People With Pulmonary Hypertension (MK-7962-023)

NCT06814145Hypertension, Pulmonary

DrugSotatercept

Merck Sharp & Dohme LLC

Phase 2

440

Monterrey

2025-04-16

Recruiting

A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)

NCT06824467Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer

DrugsSteroid mouthwash (dexamethasone·Mvasi·Acetaminophen·Sacituzumab tirumotecan

Merck Sharp & Dohme LLC

Phase 3

770

Guadalajara, Mexico City, Monterrey, Aguascalientes, Cuauhtémoc, Oaxaca City

2025-04-09

Recruiting

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

NCT06790693Breast Cancer

DrugsCDK4/6i·Inavolisib·Letrozole

Hoffmann-La Roche

Phase 3

450

Distrito Federal, MexicoCiudad de México, Monterrey, Ciudad de Huajuapan de León, Oaxaca City, Chihuahua City, D.F., Guadalajara

2025-04-09

Active, closed

A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa

NCT06840392Hidradenitis Suppurativa

DrugRemibrutinib

Novartis Pharmaceuticals

Phase 3

565

Monterrey, Culiacán, Durango

2025-03-20

Recruiting

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

NCT06883305Chronic Obstructive Pulmonary Disease (COPD)

DrugTezepelumab

AstraZeneca

Phase 3

990

Benito Juárez, Chihuahua City, Cuauhtémoc, Cuernavaca, Guadalajara, Mérida, Monterrey, Morelia

2025-03-18

Recruiting

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

NCT06841354Triple Negative Breast Neoplasms

DrugsAbraxane·Paraplatin·Sacituzumab tirumotecan·Taxol

Merck Sharp & Dohme LLC

Phase 3

1,000

Guadalajara, Benito Juárez, Mexico City, Monterrey, San Pedro Garza García, Oaxaca City, Aguascalientes, Chihuahua City

2025-03-16

Active, closed

A Study to Compare the Efficacy and Safety of BMS-986365 Versus the Investigator's Choice of Therapy in Participants With Metastatic Castration-resistant Prostate Cancer

NCT06764485Metastatic Castration-resistant Prostate Cancer

DrugsAbiraterone·Enzalutamide·Docetaxel

Celgene

Phase 3

960

Mexico City, Guadalajara, Monterrey, Chihuahua City, Puebla City

2025-03-13

Recruiting

Low Dose Teclistamab in Newly Diagnosed Multiple Myeloma Patients

NCT06758375Multiple Myeloma, Newly Diagnosed

DrugTeclistamab

Hospital Universitario Dr. Jose E. Gonzalez

Phase 2

Monterrey

2025-03-03

Recruiting

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

NCT06767514Non-Small Cell Lung Cancer

DrugsIvonescimab·Pembrolizumab

Summit Therapeutics

Phase 3

780

Aguascalientes, Guadalajara, Querétaro, Oaxaca City, Jalisco, Mexico City, Monterrey, Veracruz

2025-02-27

Active, closed

A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps

NCT06834360Chronic Rhinosinusitis With Nasal Polyps

DrugsItepekimab·Mometasone furoate

Sanofi

Phase 3

216

Guadalajara, Monterrey, Chihuahua City, Veracruz

2025-02-06

Not yet open

"Educational Intervention 'Be Yourself': Digital Innovation to Prevent Teenage Pregnancy"

NCT06824922Prevenir el Embarazo Adolescente

Universidad Autonoma de Nuevo Leon

Not applicable

150

Monterrey

2025-02-06

Recruiting

Efficacy of Human Chorionic Gonadotropin in Acute GVHD Treatment

NCT06904599Acute Graft Versus Host Disease

DrugsHuman chorionic gonadotropin·Prednisone·Dexamethasone

Hospital Universitario Dr. Jose E. Gonzalez

Phase 2

Monterrey

2025-02-01

Recruiting

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

NCT06717347Diffuse Large B-Cell Lymphoma

DrugsRituximab Biosimilar·Zilovertamab vedotin·Riabni·Ruxience

Merck Sharp & Dohme LLC

Phase 3

1,046

Torreón, Pachuca, Mexico City, Morelia, Monterrey, Oaxaca City

2025-01-27

Active, closed

A Study of the Efficacy and Safety of Efgartigimod in Patients With Primary Sjögren's Syndrome

NCT06684847Primary Sjogrens Disease

DrugEfgartigimod PH20

argenx

Phase 3

631

Torreón, León, Guadalajara, Cuernavaca, Monterrey, Culiacán, Mérida, Chihuahua City

2025-01-15

Active, closed

A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

NCT06807424Arthritis, Psoriatic

DrugIcotrokinra

Janssen Research & Development, LLC

Phase 3

813

Culiacán, Guadalajara, Mexicali, Mexico City, Monterrey, San Luis Potosí City

2025-01-09

Recruiting

Efficacy of Short-course Blinatumomab for MRD Erradication in B-ALL

NCT06886074Acute Lymphoblastic Leukemia, Measurable Residual Disease (MRD)

Hospital Universitario Dr. Jose E. Gonzalez

Phase 2

Monterrey

2025-01-02

Recruiting

Efficacy of Low-dose Venetoclax With Itraconazole + TACL for R/R ALL Patients

NCT07039877Acute Lymphobkastic Leukemia, Acute Lymphoblastic Leukaemia Recurrent, Philadelphia Chromosome Negative ALL

Hospital Universitario Dr. Jose E. Gonzalez

Phase 2

Monterrey

2025-01-02

Recruiting

A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease

NCT06500702Focal Segmental Glomerulosclerosis, Glomerulonephritis Minimal Lesion

DrugsBrivekimig·Frexalimab·Rilzabrutinib

Sanofi

Phase 2

Monterrey, Mexico City

2024-12-19

Recruiting

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

NCT06750094Colorectal Neoplasms

DrugsLeucovorin calcium/Levoleucovorin·Amivantamab·Erbitux·Avastin

Janssen Research & Development, LLC

Phase 3

700

Chihuahua City, Guadalajara, Mexico City, Monterrey, Puebla City, Querétaro, Tijuana

2024-12-12

Active, closed

A Trial to Evaluate Efficacy and Safety of Buloxibutid in People With Idiopathic Pulmonary Fibrosis.

NCT06588686Idiopathic Pulmonary Fibrosis (IPF)

Vicore Pharma AB

Phase 2

378

Mexico City, Monterrey, San Nicolás de los Garza, Oaxaca City

2024-12-09

Recruiting

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

NCT06679140COVID-19 SARS-CoV-2 Infection

DrugIbuzatrelvir

Pfizer

Phase 3

2,330

León, Pachuca, Cuernavaca, Monterrey, Mexico City, Veracruz

2024-12-08

Recruiting

A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)

NCT06667700Coronavirus Disease (COVID-19)

DrugMolnupiravir

Merck Sharp & Dohme LLC

Phase 3

3,082

León, Guadalajara, Mexico City, Cuernavaca, Monterrey, Mérida, Chihuahua City, Veracruz

2024-12-02

Active, closed

A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)

NCT06422884Idiopathic Pulmonary Fibrosis, Progressive Fibrosing Interstitial Lung Disease

DrugTaladegib

Endeavor Biomedicines, Inc.

Phase 2

213

Monterrey, San Nicolás de los Garza, San Juan del Río, Chihuahua City, Mexico City, Oaxaca City, Puebla City

2024-11-15

Active, closed

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

NCT06655896Scleroderma, Diffuse

DrugsRapcabtagene autoleucel·Rituximab

Novartis Pharmaceuticals

Phase 2

Monterrey

2024-10-29

Recruiting

Eating Disorders Genetics Initiative 2

NCT06594913Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder, Avoidant Restrictive Food Intake Disorder

University of North Carolina, Chapel Hill

Observational

20,000

Monterrey

2024-10-28

Recruiting

A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

NCT06649110Healthy Volunteers, Pulmonary Arterial Hypertension

Novartis Pharmaceuticals

Phase 1/2

232

Monterrey, San Luis Potosí City

2024-10-24

Recruiting

PPIs and In-Hospital Morbidity in Acute Variceal Bleeding With Chronic Liver Disease

NCT06861478Morbidity

DrugsPantoprazole·Omeprazole

Universidad Autonoma de Nuevo Leon

Phase 2

Monterrey

2024-10-20

Active, closed

A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

NCT06470048Diffuse Cutaneous Systemic Sclerosis

DrugIanalumab

Novartis Pharmaceuticals

Phase 2

203

Chihuahua City, Guadalajara, Mexico City, Monterrey

2024-10-09

By invitation

Long-term Safety and Efficacy Evaluation of Lunsekimig (SAR443765) in Adult Participants With Asthma

NCT06609239Asthma

DrugLunsekimig

Sanofi

Phase 2

900

Monterrey, San Juan del Río, Mérida, Chihuahua City, Durango, Veracruz

2024-09-30

Active, closed

Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma.

NCT06473779Severe Asthma

AstraZeneca

Phase 3

310

Chihuahua City, Cuauhtémoc, Monterrey

2024-09-30

Active, closed

A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast

NCT06238622Idiopathic Pulmonary Fibrosis, Progressive Pulmonary Fibrosis

DrugNerandomilast

Boehringer Ingelheim

Phase 3

1,666

Chihuahua City, Coyoacán, León, Mexico City, Monterrey, Oaxaca City

2024-09-26

Active, closed

STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss

NCT06571383Obesity

Novo Nordisk A/S

Phase 4

500

Monterrey, Ciudad Madero, Puebla City

2024-09-17

Active, closed

A Study to Assess the Efficacy and Safety of Afimkibart (Also Known as RO7790121) for Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

NCT06589986Moderately to Severely Active Ulcerative Colitis

DrugAfimkibart

Hoffmann-La Roche

Phase 3

400

Guadalajara, Monterrey

2024-09-17

Active, closed

Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab)

NCT06430866Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)

DrugsABP 234·Pembrolizumab

Amgen

Phase 3

163

LeÃ³n, Zapopan, Cuauhtémoc, Monterrey, Puebla City

2024-09-12

Recruiting

A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease

NCT06572384Lung Diseases, Interstitial

DrugBelimumab

GlaxoSmithKline

Phase 3

440

Chihuahua City, Guadalajara, Mexicali, Mexico City, Mérida, Monterrey

2024-09-11

Active, closed

A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)

NCT06581198Lupus Erythematosus, Systemic, Lupus Nephritis

DrugRapcabtagene autoleucel

Novartis Pharmaceuticals

Phase 2

179

Monterrey

2024-09-04

Recruiting

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

NCT06274801Pulmonary Arterial Hypertension

Gossamer Bio USA, Inc.

Phase 3

330

Mexico City, Monterrey

2024-09-03

Active, closed

Cognitive-Behavioral Intervention to Increase Tummy Time Practice and Maintain Healthy Weight in Infants

NCT06616467Obesity/therapy, Prevention and Control

Universidad Autonoma de Nuevo Leon

Not applicable

144

Monterrey

2024-09-02

Active, closed

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

NCT06531824Kidney Disease, Chronic

A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

Boehringer Ingelheim

Phase 3

8,371

Aguascalientes, Cuernavaca, Culiacán, Durango, Guadalajara, Mexico City, Mérida, Monterrey

2024-08-30

Recruiting

NCT06452277Advanced Non-small Cell Lung Cancer, HER2 Mutation

DrugsSevabertinib·Pemetrexed·Cisplatin·Carboplatin

Bayer

Phase 3

444

Mexico City, Monterrey, San Pedro Garza García, Naucalpan, Puebla City

2024-08-28

Active, closed

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

NCT06461897Atopic Dermatitis

DrugsUpadacitinib·Dupilumab

AbbVie

Phase 3

699

Monterrey, Veracruz

2024-08-19

Active, closed

An Extension and Crossover Vaccination Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus Given to Adults 60 Years of Age and Above Who Participated in RSV OA=ADJ-006 Study

NCT06534892Respiratory Syncytial Virus Infections

DrugRSVPreF3 OA vaccine

GlaxoSmithKline

Phase 3

10,212

Chihuahua City, León, Mexico City, Mérida, Monterrey, Oaxaca City, Querétaro, RM Pharmamexico CITY

2024-08-01

Active, closed

A Study to Assess the Efficacy, Safety, and Pharmacokinetics of Debio 4326 in Pediatric Participants With Central Precocious Puberty (LIBELULA™ Clinical Trial)

NCT06129539Central Precocious Puberty

Debiopharm International SA

Phase 3

Monterrey

2024-07-31

By invitation

Long-term Safety and Tolerability of BHV-7000

NCT06443463Focal Epilepsy

DrugOpakalim

Biohaven Therapeutics Ltd.

Phase 2

660

Mexico City, Monterrey, Obispado, Sinaloa, Tlalnepantla, Veracruz

2024-07-30

Recruiting

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

NCT06559306Depressive Disorder, Major

DrugSeltorexant

Janssen Research & Development, LLC

Phase 3

752

Mexico City, Monterrey, Nuevo León, San Luis de Potosi

2024-07-25

Active, closed

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)

NCT06455202Chronic Spontaneous Urticaria

DrugBarzolvolimab

Celldex Therapeutics

Phase 3

976

Chihuahua City, Cuauhtémoc, Guadalajara, Mérida, Monterrey, Morelia, San Juan del Río, Veracruz

2024-07-19

Recruiting

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

NCT06252649Metastatic Colorectal Cancer

DrugsLumakras·Sotorasib·Panitumumab·Bevacizumab-awwb

Amgen

Phase 3

450

Benito Juárez, Mexico City, Monterrey

2024-07-17

Active, closed

A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

NCT06468228Hidradenitis Suppurativa

DrugLutikizumab

AbbVie

Phase 3

1,400

Guadalajara, Mexico City, Monterrey, Veracruz

2024-06-27

Active, closed

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

NCT06118281Cardiovascular Risk, Acute Myocardial Infarction (AMI)

DrugZiltivekimab

Novo Nordisk A/S

Phase 3

10,000

Aguascalientes, Torreón, Guadalajara, México, Tlalpan, Cuauhtémoc, Monterrey, Culiacán

2024-06-25

Active, closed

Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma

NCT06356129Large B-cell Lymphoma

DrugsGolcadomide·Vincristine·Doxorubicin·Prednisone

Celgene

Phase 3

850

Mexico City, Morelia, Monterrey, Oaxaca City, Puebla City

2024-06-19

Recruiting

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

NCT06424288Heart Failure

Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)

Boehringer Ingelheim

Phase 3

6,712

Aguascalientes, Culiacán, Distrito Federal, Guadalajara, Irapuato, México, Monterrey, Tlalnepantla

2024-06-17

Active, closed

NCT06305754Non-small Cell Lung Cancer (NSCLC)

DrugsSteroid mouthwash (dexamethasone·Acetaminophen·Sacituzumab tirumotecan·Pemetrexed

Merck Sharp & Dohme LLC

Phase 3

550

Guadalajara, Mexico City, Monterrey, Oaxaca City

2024-06-11

Recruiting

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

NCT06430801Crohn's Disease

DrugTulisokibart

Merck Sharp & Dohme LLC

Phase 3

1,200

León, Tlajomulco de Zúñiga, Benito Juarez Ciudad de Mexico, Mexico City, Cuernavaca, Monterrey, San Pedro Garza García, Oaxaca City

2024-06-05

Recruiting

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

NCT06439277Obesity, Weight Gain

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

Eli Lilly and Company

Phase 3

300

Aguascalientes, Guadalajara, Monterrey, Puebla City

2024-06-03

Recruiting

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

NCT06419374Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

DrugPegozafermin

Hoffmann-La Roche

Phase 3

1,800

Chihuahua City, Cuautitlán Izcalli, Cuernavaca, Jalisco, Mexico City, Mérida, Monterrey

2024-05-24

Recruiting

NCT06345729Non-small Cell Lung Cancer

DrugsCalderasib·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

348

Mexico City, Monterrey, México, Oaxaca City, Querétaro

2024-05-24

Recruiting

VE303 for Prevention of Recurrent Clostridioides Difficile Infection

NCT06237452Clostridium Difficile, Clostridium Difficile Infections, Clostridium Difficile Infection Recurrence, Clostridioides Difficile Infection

Vedanta Biosciences, Inc.

Phase 3

852

Aguascalientes, Cuernavaca, Monterrey, Veracruz

2024-05-20

Recruiting

Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

NCT06307665Asthma

AstraZeneca

Phase 3

440

Chihuahua City, Guadalajara, Monterrey

2024-05-20

Active, closed

Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

NCT06309966Focal Epilepsy

DrugOpakalim

Biohaven Therapeutics Ltd.

Phase 2/3

390

Mexico City, Monterrey, Obispado, Sinaloa, Tlalnepantla, Veracruz

2024-05-13

Active, closed

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis

NCT06407934Dermatitis Atopic

DrugAmlitelimab

Sanofi

Phase 3

1,541

Monterrey, Aguascalientes, Durango, Veracruz

2024-05-08

Active, closed

A Study to Evaluate Sacituzumab Tirumotecan (MK-2870) in Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-2870-015)

NCT06356311Gastroesophageal Cancer

DrugsTrifluridine/Tipiracil·Sacituzumab tirumotecan·Irinotecan·Docetaxel

Merck Sharp & Dohme LLC

Phase 3

473

Guadalajara, Mexico City, Monterrey, Oaxaca City, San Luis Potosí City

2024-05-03

Recruiting

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

NCT05485961End Stage Kidney Disease

DrugClazakizumab

CSL Behring

Phase 2/3

3,110

Mexico City, Monterrey

2024-04-27

By invitation

ACP-204 in Adults With Alzheimer's Disease Psychosis Open Label Extension Study

NCT06194799Alzheimer's Disease Psychosis

DrugACP-204

ACADIA Pharmaceuticals Inc.

Phase 3

752

Monterrey, Culiacán, Coahuila, Estado de México, San Luis Potosí City

2024-04-23

Recruiting

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

NCT06312176Breast Neoplasms

DrugsLiposomal doxorubicin·Abraxane·Xeloda·Sacituzumab tirumotecan

Merck Sharp & Dohme LLC

Phase 3

1,200

Guadalajara, Mexico City, Monterrey, San Pedro Garza García

2024-04-14

Recruiting

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

NCT06312137Non Small Cell Lung Cancer

DrugsSacituzumab tirumotecan·Pemetrexed·Gemcitabine·Paclitaxel

Merck Sharp & Dohme LLC

Phase 3

780

Guadalajara, Monterrey, Oaxaca City, Chihuahua City

2024-04-03

Recruiting

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

NCT06256588Neoplasms, Head and Neck

DrugDostarlimab

GlaxoSmithKline

Phase 3

864

Guadajalara, Guadalajara, Mexico City, Monterrey, Oaxaca City

2024-03-21

By invitation

Effect of Consuming a Nutraceutical Composition on Signs and Symptoms in Adult Patients With Irritable Bowel Syndrome

NCT07103772Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome With Constipation, Irritable Bowel Syndrome Mixed

Universidad Autonoma de Nuevo Leon

Not applicable

Monterrey

2024-03-14

Recruiting

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

NCT05835310Systemic Lupus Erythematosus

DrugAnifrolumab

AstraZeneca

Phase 3

100

Atizapán de Zaragoza, Guadalajara, Mérida, México, Monterrey

2024-03-14

Active, closed

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab on Background Topical Corticosteroids Therapy in Participants Aged 12 Years and Older With Moderate-to-severe AD Who Have Had an Inadequate Response to Prior Biologic Therapy or an Oral JAK Inhibitor

NCT06241118Dermatitis Atopic

DrugsPimecrolimus·Amlitelimab·Tacrolimus

Sanofi

Phase 3

464

Monterrey, Veracruz

2024-02-29

Active, closed

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

NCT05827081Early Breast Cancer

DrugsLeuprolide·Goserelin·Exemestane·Ribociclib

Novartis Pharmaceuticals

Phase 3

1,466

Tlalpan, Monterrey

2024-02-28

Active, closed

Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)

NCT06260722Diabetes Mellitus, Type 2

DrugsRetatrutide·Semaglutide

Eli Lilly and Company

Phase 3

1,250

Guadalajara, Mexico City, Cuernavaca, Monterrey, Chihuahua City, Veracruz

2024-02-21

Active, closed

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

NCT06208150Multiple Myeloma

DrugsElotuzumab·Talquetamab·Velcade·Teclistamab

Janssen Research & Development, LLC

Phase 3

838

Guadalajara, Huixquilucan, Monterrey

2024-01-22

Active, closed

A 52-Week Study to Learn About the Safety and Effects of Ritlecitinib in Participants With Nonsegmental Vitiligo

NCT06163326Vitiligo

DrugRitlecitinib

Pfizer

Phase 3

394

Mexico City, Monterrey, Veracruz

2024-01-19

Recruiting

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

NCT06008197Heart Failure, Acute Heart Failure

DrugsKerendia·Finerenone

Colorado Prevention Center

Phase 3

5,200

Aguascalientes, Culiacán, Guadalajara, Cuauhtémoc, Mexico City, Morelia, Monterrey, San Nicolás

2024-01-17

Active, closed

A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment

NCT06105632Advanced or Metastatic Breast Cancer

DrugsExemestane·Everolimus·Fulvestrant

Pfizer

Phase 2

333

Mexico City, Monterrey, Oaxaca City, Veracruz

2024-01-09

Recruiting

Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

NCT06136624Prostate Cancer Metastatic

DrugsFludrocortisone acetate·Opevesostat·Zytiga·Hydrocortisone

Merck Sharp & Dohme LLC

Phase 3

1,310

Guadalajara, Mexico City, Monterrey, Mérida

2023-12-31

Recruiting

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

NCT06119581Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

DrugsOlomorasib·Pemetrexed·Cisplatin·Carboplatin

Eli Lilly and Company

Phase 3

1,264

Guadalajara, Juriquilla, León, Mexico City, Monterrey, Oaxaca City, Puebla City, San Pedro Garza García

2023-12-21

Recruiting

A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)

NCT06136650Metastatic Castration-resistant Prostate Cancer (mCRPC), Prostatic Neoplasms

DrugsFludrocortisone acetate·Opevesostat·Prednisone Acetate·Zytiga

Merck Sharp & Dohme LLC

Phase 3

1,314

Guadalajara, Mexico City, Tlalpan, Monterrey

2023-12-18

Recruiting

Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

NCT06170788Non-small Cell Lung Cancer (NSCLC)

DrugsSacituzumab tirumotecan·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

614

Guadalajara, Mexico City, Monterrey, San Luis Potosí City, Oaxaca City, Puebla City

2023-12-15

Active, closed

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

NCT06141473Multiple Sclerosis

DrugsCholestyramine·Activated Charcoal·Teriflunomide·Frexalimab

Sanofi

Phase 3

1,655

Guadalajara, Monterrey, Culiacán, Mérida, Mexico City, Tlalnepantla, Veracruz

2023-12-13

Active, closed

A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

NCT06065748Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer

DrugsGiredestrant·Ribociclib·Abemaciclib·Palbociclib

Hoffmann-La Roche

Phase 3

1,050

Guadalajara, Mexico City, Monterrey, Oaxaca City, Queréaro

2023-12-11

Active, closed

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

NCT06077760Non-small Cell Lung Cancer

DrugsIntismeran autogene·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

868

Pachuca, Guadalajara, Mexico City, Monterrey, Chihuahua City, Distrito Federal, Oaxaca City

2023-12-06

Active, closed

A Study to Evaluate Efficacy and Safety of Povorcitinib in Participants With Nonsegmental Vitiligo (STOP-V1)

NCT06113445NonSegmental Vitiligo

DrugPovorcitinib

Incyte Corporation

Phase 3

467

Deleg. Cuauhtemoc, Durango, Monterrey, Morelia, Providencia 5TA Seccion

2023-11-29

Active, closed

OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer

NCT06016738Breast Cancer, Advanced Breast Cancer, Metastatic Breast Cancer, ER Positive Breast Cancer

DrugsPalazestrant·Exemestane·Anastrozole·Letrozole

Olema Pharmaceuticals, Inc.

Phase 3

510

Guadalajara, Mexico City, Puebla City, San Luis Potosí City, Monterrey, Oaxaca City, Sinaloa

2023-11-16

Recruiting

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

NCT05920356Non-Small Cell Lung Cancer (NSCLC)

DrugsLumakras·Sotorasib·Pembrolizumab

Amgen

Phase 3

750

Guadalajara, Mexico City, Monterrey, Oaxaca City

2023-11-16

Recruiting

ACP-204 in Adults With Alzheimer's Disease Psychosis

NCT06159673Alzheimer's Disease Psychosis

DrugACP-204

ACADIA Pharmaceuticals Inc.

Phase 2/3

1,074

Monterrey, Coahuila, Estado de México, Mazatlán, Mexico City, Nuevo León, San Luis Potosí City, Sinaloa

2023-11-14

Active, closed

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

NCT06074588Non-small Cell Lung Cancer (NSCLC)

DrugsTaxotere·Sacituzumab tirumotecan·Pemetrexed·Docetaxel

Merck Sharp & Dohme LLC

Phase 3

556

Guadalajara, Monterrey, Oaxaca City, Puebla City

2023-11-12

Active, closed

A 104-Week Study of Ritlecitinib Oral Capsules in Adults With Nonsegmental Vitiligo (Active and Stable) Tranquillo 2

NCT06072183Stable Nonsegmental Vitiligo, Active Nonsegmental Vitiligo

DrugRitlecitinib

Pfizer

Phase 3

1,571

Chihuahua City, Mexico City, Morelia, Monterrey, Veracruz

2023-11-08

Active, closed

A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma

NCT06054555Melanoma

DrugsOpdivo·Nivolumab

Amgen

Phase 3

633

León, Guadalajra, Mexico City, Monterrey, San Pedro Garza García, Juchitán de Zaragoza, San Luis Potosí City, Culiacán

2023-11-02

Active, closed

Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients

NCT05899608Non-Small Cell Lung Cancer

DrugsIvonescimab·Pembrolizumab

Summit Therapeutics

Phase 3

1,600

Guadalajara, La Paz, Mexico City, Monterrey

2023-10-26

Active, closed

A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)

NCT06052059Ulcerative Colitis

DrugTulisokibart

Merck Sharp & Dohme LLC

Phase 3

1,109

León, Guadalajara, Tlajumulco de Zuniga, Mexico City, Monterrey, Mérida, Chihuahua City, Oaxaca City

2023-10-25

Recruiting

Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)

NCT06079671Locally Advanced Cervical Cancer

DrugVolrustomig

AstraZeneca

Phase 3

800

Coyoacán, Culiacán, Guadalajara, Guadalajra, Mexico City, México, Monterrey

2023-09-22

Active, closed

A Study of Investigational Tirzepatide (LY3298176) Doses in Participants With Type 2 Diabetes and Obesity

NCT06037252Type 2 Diabetes, Obesity

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

Eli Lilly and Company

Phase 2

414

Tijuana, Guadalajara, Cuauhtémoc, Ciudad de México, Mexico City, Monterrey, Ciudad Madero

2023-09-21

Recruiting

NCT05894239Metastatic Breast Cancer

DrugsPhesgo·Inavolisib

Hoffmann-La Roche

Phase 3

230

Guadalajara, Mexico City, Monterrey

2023-09-08

Active, closed

Clairleafᵀᴹ: A Study to Test Long-term Treatment With BI 1291583 in People With Bronchiectasis Who Took Part in a Previous Study With This Medicine

NCT05846230Bronchiectasis

DrugVerducatib

Boehringer Ingelheim

Phase 2

268

Chihuahua City, Monterrey, Monterrey, Nuevo León, Oaxaca City, Tlalnepantla

2023-09-08

Recruiting

A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis

NCT06016842Primary Biliary Cholangitis (PBC)

DrugElafibranor

Ipsen

Phase 3

276

Guadalajara, Jalisco, Mexico City, Monterrey, Yucatán

2023-08-31

Active, closed

A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma Exacerbations

NCT06052267Asthma

DrugAlbuterol sulfate

Teva Branded Pharmaceutical Products R&D LLC

Phase 3

2,769

Chihuahua City, Guadalajara, Monterrey, Oaxaca City, Villahermosa

2023-08-30

Recruiting

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

NCT06126224Psychosis Associated With Alzheimer's Disease

DrugKarXT

Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Phase 3

500

Saltillo Centro, Zona Urbana Río Tijuana, Zapopan, Monterrey, Culiacán, México

2023-08-28

Recruiting

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

NCT05980949Psychosis Associated With Alzheimer's Disease

DrugKarXT

Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Phase 3

1,000

Saltillo Centro, Zona Urbana Río Tijuana, Zapopan, Monterrey, Culiacán, México

2023-07-11

Active, closed

A Study of Zigakibart in Adults With IgA Nephropathy

NCT05852938IgA Nephropathy, Immunoglobulin A Nephropathy

DrugZigakibart

Novartis Pharmaceuticals

Phase 3

383

Chihuahua, Barrio Belisario Domínguez Secc, Oaxaca, Aguascalientes, Chihuahua City, Monterrey

2023-07-06

Active, closed

A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

NCT05878769Chronic Obstructive Pulmonary Disease

Hoffmann-La Roche

Phase 3

2,000

Guadalajara, Santa Cecilia, Monterrey

2023-06-28

Active, closed

A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus

NCT05672576Lupus Erythematosus, Systemic

DrugCenerimod

Viatris Innovation GmbH

Phase 3

451

Cuernavaca, Guadalajara, León, Mexico City, Mérida, Monterrey, Oaxaca City, Querétaro

2023-06-26

Active, closed

A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma

NCT05827016Multiple Myeloma

DrugsIberdomide·Lenalidomide

Bristol-Myers Squibb

Phase 3

1,230

Monterrey, Toluca

2023-06-22

Active, closed

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

NCT05889182Hidradenitis Suppurativa

DrugUpadacitinib

AbbVie

Phase 3

1,328

Guadalajara, Monterrey, Mexico City

2023-06-21

Recruiting

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

NCT05714085Heart Failure, Left Ventricular Systolic Dysfunction

DrugVericiguat

Merck Sharp & Dohme LLC

Phase 2/3

342

León, Guadalajara, Mexico City, Monterrey, Hacienda de Las Palmas, Ciudad Madero, Aguascalientes, Colima

2023-05-31

Active, closed

ELACESTRANT in Women and Men With CDK4/6 Inhibitor-Naive Estrogen Receptor Positive, HER-2 Negative Metastatic Breast Cancer Study

NCT05596409Metastatic Breast Cancer

DrugElacestrant

Stemline Therapeutics, Inc.

Phase 2

Monterrey, Mexico City, Puebla City

2023-05-19

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

NCT05716100Focal Onset Seizures

DrugAzetukalner

Xenon Pharmaceuticals Inc.

Phase 3

360

Benito Juárez, Mexico City, Monterrey, Sinaloa

2023-05-09

Active, closed

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy

NCT05840211Locally Advanced or Unresectable Metastatic Breast Cancer, Stage IV Breast Cancer

DrugsAbraxane·Xeloda·Sacituzumab Govitecan·Taxol

Gilead Sciences

Phase 3

654

Cancún, Mexico City, México, Monterrey, Puebla City, San Pedro Garza García, Yucatán

2023-05-08

Active, closed

A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma

NCT05757102Asthma

DrugFF/UMEC/VI

GlaxoSmithKline

Phase 3

138

Guadalajara, Monterrey, San Juan del Río

2023-04-24

Active, closed

Validating Artificial Intelligence Effectiveness Defined Lung Nodule Malignancy Score in Patients With Pulmonary Nodule.

NCT05817110Lung Malignancy

AstraZeneca

Observational

712

Monterrey, Mexico City

2023-04-20

Recruiting

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

NCT05774951Breast Cancer, Early Breast Cancer

DrugsCamizestrant·Tamoxifen·Exemestane·Anastrozole

AstraZeneca

Phase 3

4,300

Aguascalientes, Alc. Cuauhtémoc, Colonia Lindavista, Mexico City, Mérida, México, Monterrey, San Luis Potosí City

2023-03-31

Active, closed

A Study of TAR-200 in Combination With Cetrelimab or TAR-200 Alone Versus Intravesical Bacillus Calmette-Guérin (BCG) in Participants With BCG-naïve High-risk Non-muscle Invasive Bladder Cancer (HR-NMIBC)

NCT05714202Bladder Cancer

DrugsTAR-200·Cetrelimab

Janssen Research & Development, LLC

Phase 3

1,135

Mexico City, Mérida, Monterrey, San Luis Potosí City

2023-03-23

By invitation

A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

NCT05735483Atopic Dermatitis, Eczema

DrugLebrikizumab

Eli Lilly and Company

Phase 3

338

Chihuahua City, Zapopan, Mexico City, Cuernavaca, Monterrey, Veracruz

2023-03-09

Active, closed

A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

NCT05739383Primary Prevention of Atherosclerotic Cardiovascular Disease

DrugInclisiran

Novartis Pharmaceuticals

Phase 3

14,012

León, Actopan, Guadalajara, Gustavo Adolfo Madero, Mexico City, Tlalpan, Cuernavaca, Monterrey

2023-03-09

Recruiting

A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works

NCT05744921Paroxysmal Nocturnal Hemoglobinuria

DrugsCemdisiran·Pozelimab

Regeneron Pharmaceuticals

Phase 3

202

Monterrey

2023-03-07

Active, closed

An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH)

NCT05649748Pulmonary Arterial Hypertension

DrugTreprostinil Palmitil

Insmed Incorporated

Phase 2/3

Lomas de Guevara, Monterrey, Mexico City, San Luis Potosí City

2023-03-07

Active, closed

REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels

NCT05669755Cardiovascular Disease

DrugsCagrilintide·Semaglutide

Novo Nordisk A/S

Phase 3

7,101

Guadalajara, Cuernavaca, Monterrey, San Luis Potosí City, Culiacán, Ciudad Madero, Xalapa, Aguascalientes

2023-03-01

Active, closed

Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-3475-D46)

NCT05609968Carcinoma, Non-Small-Cell Lung

DrugsSacituzumab Govitecan·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

614

Tijuana, Monterrey, Mérida, Aguascalientes, Oaxaca City

2023-02-06

Active, closed

Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP)

NCT05653349Primary Immune Thrombocytopenia (ITP)

DrugIanalumab

Novartis Pharmaceuticals

Phase 3

226

Mexico City, Monterrey

2023-02-03

Active, closed

A Study of Efficacy and Safety of Ianalumab Versus Placebo in Addition to Eltrombopag in Primary Immune Thrombocytopenia Patients Who Failed Steroids

NCT05653219Primary Immune Thrombocytopenia

DrugsEltrombopag·Ianalumab

Novartis Pharmaceuticals

Phase 3

152

Saltillo, Morelia, Monterrey

2023-02-02

Active, closed

A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants With Severe Hemophilia

NCT05662319Hemophilia

DrugsAntithrombin·Clotting factor concentrates·Fitusiran

Sanofi

Phase 3

Monterrey, Chihuahua City, Veracruz

2023-02-01

Active, closed

A Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With Surgery

NCT05608291Melanoma

DrugsFianlimab·Cemiplimab·Keytruda·Pembrolizumab

Regeneron Pharmaceuticals

Phase 3

1,564

León, Guadalajara, Monterrey, Culiacán, Mérida, Veracruz

2023-01-16

Active, closed

ABTECT - Maintenance

NCT05535946Ulcerative Colitis

DrugObefazimod

Abivax S.A.

Phase 3

1,116

Irapuato, Monterrey, Veracruz

2023-01-16

Active, closed

A Study to Evaluate Effectiveness and Safety of Deucravacitinib (BMS-986165) Compared With Placebo in Participants With Active Systemic Lupus Erythematosus

NCT05620407Systemic Lupus Erythematosus

DrugDeucravacitinib

Bristol-Myers Squibb

Phase 3

513

Torreón, León, Guadajalara, Zapopan, Mexico City, Cuernavaca, Monterrey, Chihuahua City

2023-01-12

Recruiting

Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

NCT05712200Atrial Fibrillation (AF)

DrugAbelacimab

Anthos Therapeutics, Inc.

Phase 3

2,500

Aguascalientes, Chihuahua City, Culiacán, Guadalajara, Guerrero, Mexico City, Monterrey, Querétaro

2022-12-27

Active, closed

Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (OCEAN(a)) - Outcomes Trial

NCT05581303Atherosclerotic Cardiovascular Disease

DrugOlpasiran

Amgen

Phase 3

7,297

Aguascalientes, Chihuahua City, Guadalajara, Monterrey, Culiacán, Xalapa, Mexico City

2022-12-14

Recruiting

Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

NCT05624450Viral Lung Infection and Acute Respiratory Failure

DrugTozorakimab

AstraZeneca

Phase 3

3,527

Aguascalientes, Guadalajara, Mexico City, Monterrey, San Luis Potosí City, Tlalpan, Xalapa

2022-12-13

Active, closed

Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1)

NCT05501886Breast Cancer

DrugsGedatolisib·Alpelisib·Palbociclib·Fulvestrant

Celcuity Inc

Phase 3

701

Mexico City, Monterrey, Morelia, Nuevo León, Querétaro, Saltillo

2022-12-08

Recruiting

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

NCT05457283Chronic Kidney Disease, Proteinuria, Children

DrugFinerenone

Bayer

Phase 3

100

Aguascalientes, México D.F., México, D.F., Monterrey, Veracruz

2022-11-08

Active, closed

A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight

NCT05567796Obesity

DrugsCagrilintide·Semaglutide

Novo Nordisk A/S

Phase 3

3,400

Guadalajara, Monterrey, Aguascalientes

2022-11-01

Active, closed

A Study of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

NCT05559359Atopic Dermatitis, Eczema

DrugLebrikizumab

Eli Lilly and Company

Phase 3

377

Chihuahua City, Cuernavaca, Mexico City, Monterrey, Veracruz, Zapopan

2022-10-18

Active, closed

A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer

NCT05514054Breast Neoplasms

DrugsImlunestrant·Tamoxifen·Exemestane·Anastrozole

Eli Lilly and Company

Phase 3

8,000

Chihuahua City, Ciudad Madero, Guadalajara, León, Mexico City, Monterrey, Oaxaca City, Puebla City

2022-10-04

Recruiting

Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

NCT05327114Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

DrugNipocalimab

Janssen Research & Development, LLC

Phase 2/3

201

Monterrey, Tlalnepantla

2022-09-23

Active, closed

The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)

NCT05540327Systemic Lupus Erythematosus

DrugEnpatoran

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

Phase 2

381

Cuernavaca, Guadalajara, Mexicali, Mexico City, Mérida, México, Monterrey, Torreón

2022-09-16

Active, closed

A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

NCT05528510Colitis, Ulcerative

DrugsGuselkumab 1·Guselkumab 2·Guselkumab 3

Janssen Research & Development, LLC

Phase 3

418

Chihuahua City, Guadalajara, Mexico City, Mérida, Monterrey, Saltillo, San Pedro Garza García

2022-09-13

Active, closed

Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial

NCT05334368Hypereosinophilic Syndrome

DrugDepemokimab

GlaxoSmithKline

Phase 3

110

Guadalajara, Monterrey, Veracruz

2022-09-06

By invitation

Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease

NCT04905693Idiopathic Pulmonary Fibrosis, Interstitial Lung Disease, Progressive Pulmonary Fibrosis

DrugTreprostinil

United Therapeutics

Phase 3

1,850

Monterrey, Mexico City

2022-09-06

Recruiting

Asciminib Roll-over Study

NCT04877522Chronic Myelogenous Leukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

DrugsAsciminib single agent·Bosutinib·ABL001·Nilotinib

Novartis Pharmaceuticals

Phase 4

347

Monterrey

2022-08-30

Active, closed

Long-Term Safety and Efficacy Evaluation of Amlitelimab in Participants of Previous Amlitelimab Moderate to Severe Atopic Dermatitis Clinical Trials

NCT05492578Dermatitis Atopic

DrugAmlitelimab

Sanofi

Phase 2/3

1,856

Monterrey, Durango, Veracruz

2022-08-22

Active, closed

A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes

NCT05433584Type 2 Diabetes

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

Eli Lilly and Company

Phase 4

780

Guadalajara, Monterrey, Chihuahua City

2022-08-01

Active, closed

NCT05382286Triple Negative Breast Cancer, PD-L1 Positive

DrugsAbraxane·Sacituzumab Govitecan·Taxol·Nab-paclitaxel

Gilead Sciences

Phase 3

443

Chihuahua City, Culiacán, Guadalajara, Mexico City, Mérida, México, Monterrey, San Luis Potosí City

2022-07-25

Active, closed

LYT-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

NCT05321420Idiopathic Pulmonary Fibrosis

DrugsDeupirfenidone·Pirfenidone

PureTech

Phase 2

240

Monterrey, San Nicolás de los Garza, Calpulalpan, Oaxaca City, San Pedro Garza García

2022-07-22

Active, closed

Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

NCT05382299Triple Negative Breast Cancer, PD-L1 Negative

DrugsAbraxane·Sacituzumab Govitecan·Nab-paclitaxel·Gemcitabine

Gilead Sciences

Phase 3

623

Chihuahua City, Culiacán, Guadalajara, Mexico City, Mérida, México, Monterrey, San Luis Potosí City

2022-07-20

Active, closed

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

NCT05296798Locally Advanced or Metastatic Breast Cancer

DrugsPhesgo·Giredestrant·Pertuzumab·Trastuzumab

Hoffmann-La Roche

Phase 3

922

La Paz, Guadalajara, D.F., Mexico City, Monterrey, Querétaro City, San Luis Potosí City, Chihuahua City

2022-07-18

Active, closed

Clinical Study of Fianlimab in Combination With Cemiplimab Versus Pembrolizumab in Adolescent and Adult Patients With Previously Untreated Unresectable Locally Advanced or Metastatic Melanoma

NCT05352672Melanoma

DrugsFianlimab·Cemiplimab·Keytruda·Pembrolizumab

Regeneron Pharmaceuticals

Phase 3

1,546

Tuxtla Gutiérrez, León, Guadalajara, Zapopan, Monterrey, Culiacán, Mérida, Chihuahua City

2022-07-14

Active, closed

Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis

NCT05126277Lupus Nephritis

DrugIanalumab

Novartis Pharmaceuticals

Phase 3

452

León, Monterrey, Oaxaca City, Querétaro

2022-07-14

Active, closed

Study for Participants Continuing From Pfizer-sponsored Palbociclib (a Study Medicine) Studies

NCT05226871Breast Cancer, Head and Neck Cancer

DrugsPalbociclib·Letrozole·Fulvestrant·Cetuximab

Pfizer

Phase 2

Monterrey

2022-07-07

Recruiting

Study to Evaluate Weight Gain as Assessed by Change in BMI Z-score in Pediatric Subjects With Schizophrenia or Bipolar I Disorder

NCT05303064Schizophrenia, Bipolar I Disorder

DrugsOLZ/SAM·Olanzapine

Alkermes, Inc.

Phase 3

220

Culiacán, Estado de México, León, Monterrey

2022-06-30

By invitation

A Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and it's Effects on Symptoms in Adults With Systemic Lupus Erythematosus (SLE)

NCT05352919Systemic Lupus Erythematosus (SLE)

DrugLitifilimab

Biogen

Phase 3

864

Guadalajara, Mexico City, Cuernavaca, Monterrey, Mérida, Chihuahua City, Durango

2022-06-10

Recruiting

A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB

NCT05183646FSGS

DrugRepagermanium

Dimerix Bioscience Pty Ltd

Phase 3

286

Aguascalientes, Chihuahua City, Culiacán, Guadalajara, Monterrey

2022-05-30

Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

NCT05039619Lupus Nephritis

DrugsAcetaminophen/Paracetamol·Diphenhydramine hydrochloride·Mycophenolate Mofetil·Methylprednisolone

Hoffmann-La Roche

Phase 2

Guadalajara, Mexico City, Monterrey

2022-05-12

Active, closed

A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis

NCT05269004Multiple Sclerosis

DrugOcrelizumab

Hoffmann-La Roche

Phase 3

1,300

Guadalajara, Mexico City, Tlalnepantla, Monterrey, Culiacán, Chihuahua City, México

2022-05-03

Active, closed

A Study Evaluating Efficacy and Safety of Mosunetuzumab in Combination With Polatuzumab Vedotin Compared to Rituximab in Combination With Gemcitabine Plus Oxaliplatin in Participants With Relapsed or Refractory Aggressive B-Cell Non-Hodgkin's Lymphoma

NCT05171647Non-Hodgkin Lymphoma

DrugsMosunetuzumab·Polatuzumab Vedotin·Tocilizumab·Rituximab

Hoffmann-La Roche

Phase 3

208

Mexico City, Monterrey, Distrito Federal, México

2022-04-25

Recruiting

(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors

NCT05208047Advanced Gastrointestinal Stromal Tumors, Metastatic Cancer

DrugsBezuclastinib·Sunitinib·Midazolam

Cogent Biosciences, Inc.

Phase 3

482

Aguascalientes, Monterrey, Oaxaca City

2022-04-14

Active, closed

A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer)

NCT05288166Prostatic Neoplasms, Neoplasm Metastasis, Urogenital Neoplasms, Physiological Effects of Drugs

DrugsAbiraterone·Abemaciclib·Prednisolone·Prednisone

Eli Lilly and Company

Phase 3

925

Guadalajara, Mexico City, Monterrey, Culiacán, Chihuahua City, Oaxaca City

2022-04-14

Active, closed

Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008)

NCT05224141Small Cell Lung Carcinoma

DrugsPembrolizumab/Vibostolimab·Platinol-AQ·Tecentriq·Paraplatin

Merck Sharp & Dohme LLC

Phase 3

460

Guadalajara, Mexico City, Monterrey, Oaxaca City

2022-03-24

Active, closed

A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)

NCT05239728Carcinoma, Renal Cell

DrugsBelzutifan·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

1,800

Guadalajara, Mexico City, Monterrey, Querétaro City, Culiacán, Oaxaca City, Puebla City

2022-03-15

Active, closed

A Study to Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid Tumors

NCT05262400Breast Cancer, Solid Tumors

DrugsPF-07104091·Atirmociclib

Pfizer

Phase 1/2

235

Mexico City, Monterrey, Mérida

2022-03-14

Active, closed

A Study to Evaluate the Effect of Venglustat Tablets on Neuropathic and Abdominal Pain in Male and Female Participants ≥16 Years of Age With Fabry Disease

NCT05206773Fabry Disease

DrugVenglustat

Sanofi

Phase 3

122

Monterrey, Mexico City

2022-03-11

Active, closed

Abemaciclib (LY2835219) Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast Cancer

NCT05169567Breast Neoplasm, Neoplasm Metastasis

DrugsAbemaciclib·Fulvestrant

Eli Lilly and Company

Phase 3

368

Mexicali, Tijuana, Guadalajara, Monterrey, San Luis Potosí City

2022-03-11

Recruiting

EPIC-Peds: A Study to Learn About the Study Medicine Called PF-07321332 (Nirmatrelvir)/Ritonavir in Patients Under 18 Years of Age With COVID-19 That Are Not Hospitalized But Are at Risk for Severe Disease

NCT05261139COVID-19

DrugsNirmatrelvir·Ritonavir

Pfizer

Phase 3

160

Mexico City, Cuernavaca, Monterrey, Mérida, Aguascalientes, Veracruz

2022-03-07

Active, closed

Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations

NCT05215340Metastatic Non Small Cell Lung Cancer

DrugsDato-DXd·Keytruda·Pembrolizumab

Daiichi Sankyo

Phase 3

740

Cuauhtémoc, Guadalajara, Monterrey, Oaxaca City, San Luis Potosí City

2022-03-04

Recruiting

Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)

NCT04665037Invasive Fungal Infection

DrugPosaconazole

Merck Sharp & Dohme LLC

Phase 2

Mexico City, Monterrey

2022-02-22

Active, closed

A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC)

NCT04819100Carcinoma, Non-Small-Cell Lung

DrugSelpercatinib

Eli Lilly and Company

Phase 3

152

Guadalajara, Mexico City, Monterrey

2021-12-20

Active, closed

Study Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Adult Patients With Uncontrolled Moderate to Severe Asthma

NCT05097287Asthma

DrugDupilumab

Sanofi

Phase 4

1,339

Guadalajara, Mexico City, Monterrey, San Juan del Río, Villahermosa, Chihuahua City, Durango, Oaxaca City

2021-12-16

Active, closed

Pembrolizumab/Placebo Plus Paclitaxel With or Without Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer (MK-3475-B96/KEYNOTE-B96/ENGOT-ov65).

NCT05116189Ovarian Cancer, Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms

DrugsZirabev·Taxotere·Avastin·Keytruda

Merck Sharp & Dohme LLC

Phase 3

643

La Paz, Mexico City, Monterrey, Oaxaca City

2021-12-13

Active, closed

A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

NCT05152147Gastric Neoplasms, Gastroesophageal Adenocarcinoma, Esophageal Adenocarcinoma

DrugsZanidatamab·Herceptin·Trastuzumab·Adrucil

Jazz Pharmaceuticals

Phase 3

920

Mexico City, Monterrey, Oaxaca City

2021-12-02

Active, closed

Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease

NCT05030428Atherosclerotic Cardiovascular Disease

DrugInclisiran sodium

Novartis Pharmaceuticals

Phase 3

17,004

Guadalajara, Mexico City, Monterrey, Tlalnepantla, Mérida, Acapulco, Aguascalientes, Chihuahua City

2021-11-23

Active, closed

Efficacy and Safety of Frexalimab (SAR441344) in the Treatment of Systemic Lupus Erythematosus

NCT05039840Systemic Lupus Erythematosus

DrugFrexalimab

Sanofi

Phase 2

109

Mexico City, Monterrey, Mérida, Chihuahua City, Veracruz

2021-11-10

Active, closed

Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

NCT04994717Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)

DrugBlinatumomab

Amgen

Phase 3

303

Mexico City, Monterrey, Huixquilucan

2021-11-02

Active, closed

Savolitinib Plus Durvalumab Versus Sunitinib and Durvalumab Monotherapy in MET-Driven, Unresectable and Locally Advanced or Metastatic PRCC

NCT05043090Papillary Renal Cell Carcinoma

DrugsSavolitinib·Sunitinib·Durvalumab

AstraZeneca

Phase 3

148

Aguascalientes, Monterrey, Querétaro, Toluca

2021-10-28

Active, closed

A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Erythematosus

NCT04963296Systemic Lupus Erythematosus

DrugsAcetaminophen/Paracetamol·Diphenhydramine hydrochloride·Methylprednisolone·Obinutuzumab

Hoffmann-La Roche

Phase 3

303

Torreón, Mexicali, Mexico City, Monterrey, Culiacán

2021-10-26

Active, closed

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

NCT04861259Atypical Hemolytic Uremic Syndrome

DrugCrovalimab

Hoffmann-La Roche

Phase 3

Distrito Federal, Mexico City, Monterrey, Zapopan

2021-10-22

By invitation

Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects

NCT04987229Bipolar I Disorder, Schizophrenia

DrugOLZ/SAM

Alkermes, Inc.

Phase 3

236

León, Monterrey, Culiacán, Gustavo A. Madero

2021-10-22

Active, closed

A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer

NCT04958239Neoplasms

DrugsEzabenlimab·Pembrolizumab

Boehringer Ingelheim

Phase 1

151

Mexico City, México, Monterrey

2021-10-18

Active, closed

A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

NCT04895696Systemic Lupus Erythematosus

DrugAfimetoran

Beeline Medicines Corporation

Phase 2

248

Chihuahua City, León, Guadalajara, Zapopan, Mérida, Mexico City, Monterrey

2021-10-11

Active, closed

A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer

NCT04975308Breast Neoplasms, Neoplasm Metastasis

DrugsImlunestrant·Exemestane·Abemaciclib·Fulvestrant

Eli Lilly and Company

Phase 3

874

Torreón, Álvaro Obregón, Mexico City, Monterrey, San Pedro Garza García, Chihuahua City, Oaxaca City, Puebla City

2021-10-04

Recruiting

A Study to Learn About the Study Medicine Elranatamab Alone and With Daratumumab in People With Multiple Myeloma Who Have Received Other Treatments

NCT05020236Multiple Myeloma

DrugsDarzalex·Elranatamab·Pomalidomide·Daratumumab

Pfizer

Phase 3

893

Colonia Valle de Las Palmas, Monterrey, Oaxaca City, Veracruz

2021-10-04

Active, closed

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

NCT05059522Advanced Malignancies, NSCLC, Ovarian Cancer, Urothelial Cancer

DrugsCMP 001·Utomilumab·Talazoparib·Axitinib

Pfizer

Phase 3

Monterrey, Oaxaca City

2021-09-29

Active, closed

A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)

NCT04961996Early Breast Cancer

DrugGiredestrant

Hoffmann-La Roche

Phase 3

4,170

Mexicali, León, Guadalajara, Mexico City, Monterrey, Oaxaca City, Querétaro City, Culiacán

2021-08-27

Active, closed

A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )

NCT04849728NASH - Nonalcoholic Steatohepatitis

Inventiva Pharma

Phase 3

1,000

Guadalajara, Cuauhtémoc, Mexico City, Cuernavaca, Monterrey, Mérida, Metepec, Oaxaca City

2021-08-19

Active, closed

Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab and Enfortumab Vedotin in Patients With Muscle Invasive Bladder Cancer Ineligible to Cisplatin or Who Refuse Cisplatin

NCT04960709Muscle Invasive Bladder Cancer

DrugsEnfortumab Vedotin·Tremelimumab·Durvalumab

AstraZeneca

Phase 3

712

Colima, Monterrey

2021-08-05

By invitation

A Study to Evaluate the Safety and Tolerability of Dapirolizumab Pegol in Study Participants With Systemic Lupus Erythematosus

NCT04976322Systemic Lupus Erythematosus

UCB Biopharma SRL

Phase 3

760

Chihuahua City, Cuernavaca, Guadalajara, León, Mérida, Monterrey

2021-07-27

Active, closed

A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)

NCT04857034Lupus Erythematosus, Discoid, Lupus Erythematosus, Subacute Cutaneous

DrugDeucravacitinib

Bristol-Myers Squibb

Phase 2

Guadalajara, Zapopan, Monterrey, Aguascalientes, Mexico City

2021-07-12

Recruiting

A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine

NCT04965675Chronic Migraine in Children

DrugEptinezumab

H. Lundbeck A/S

Phase 3

285

Durango, Guadalajara, Zapopan, Morelia, Monterrey, Culiacán, México, Chihuahua City

2021-06-30

Active, closed

Efficacy and Safety Comparison of Niraparib to Placebo in Participants With Human Epidermal Growth Factor 2 Negative (HER2-) Breast Cancer Susceptibility Gene Mutation (BRCAmut) or Triple-Negative Breast Cancer (TNBC) With Molecular Disease

NCT04915755Neoplasms, Breast

DrugNiraparib

GlaxoSmithKline

Phase 3

León, Mexico City, Monterrey

2021-06-28

Active, closed

Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49)

NCT04895358Breast Neoplasms

DrugsLiposomal doxorubicin·Abraxane·Xeloda·Taxol

Merck Sharp & Dohme LLC

Phase 3

342

Guadalajara, Mexico City, Monterrey, Chihuahua City, Oaxaca City

2021-06-18

Active, closed

A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus

NCT04895241Lupus Erythematosus, Systemic

DrugLitifilimab

Biogen

Phase 3

548

Guadalajara, Mexico City, Cuernavaca, Monterrey, Mérida, Chihuahua City, Durango, Veracruz

2021-05-25

Active, closed

A Study of Subcutaneous Nivolumab Versus Intravenous Nivolumab in Participants With Previously Treated Clear Cell Renal Cell Carcinoma That is Advanced or Has Spread

NCT04810078Clear Cell Renal Cell Carcinoma

DrugsBMS-986298·Opdivo·Nivolumab

Bristol-Myers Squibb

Phase 3

681

Torreón, Tlalpan, Monterrey, Querétaro City, San Luis Potosí City

2021-05-21

Active, closed

Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC

NCT04821622Prostate Cancer

DrugsTalazoparib·Enzalutamide

Pfizer

Phase 3

599

León, Monterrey, Oaxaca City, Naucalpan, Veracruz

2021-05-12

Active, closed

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

NCT07218029Pulmonary Arterial Hypertension

DrugSotatercept

Merck Sharp & Dohme LLC

Phase 3

815

Mexico City, Monterrey

2021-05-12

Active, closed

A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy

NCT04873362Breast Cancer

DrugsTrastuzumab emtansine·Herceptin·Tecentriq·Trastuzumab

Hoffmann-La Roche

Phase 3

1,188

La Paz, Distrito Federal, Mexico City, Monterrey, Oaxaca City

2021-05-04

Active, closed

A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

NCT04736706Carcinoma, Renal Cell

DrugsPembrolizumab/Quavonlimab·Belzutifan·Lenvatinib·Keytruda

Merck Sharp & Dohme LLC

Phase 3

1,688

Guadalajara, Mexico City, Monterrey, Querétaro City, Oaxaca City

2021-04-14

Active, closed

Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)

NCT04822181Non-alcoholic Steatohepatitis

A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease

Novo Nordisk A/S

Phase 3

1,205

Acapulco de Juárez, Guadalajara, Mexico City, Monterrey, San Pedro Garza García, Culiacán, Mérida, México

2021-04-01

Active, closed

Safety and Immunogenicity of Extended 2-dose Regimens of 9-valent Human Papillomavirus (9vHPV) Vaccine (V503-069)

NCT04708041Papillomavirus Infections

DrugNonavalent HPV vaccine

Merck Sharp & Dohme LLC

Phase 3

700

Mexico City, Morelia, Monterrey, Mérida

2021-03-15

Active, closed

NCT04711252ER-Positive HER2-Negative Breast Cancer

DrugsCamizestrant·Anastrozole·Palbociclib

AstraZeneca

Phase 3

1,371

Del. Cuauhtemoc, La Paz, Mexico City, Monterrey, Puebla City, Toluca

2021-01-28

Active, closed

A Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic Melanoma

NCT04657991Melanoma

DrugsEncorafenib·Binimetinib·Keytruda·Pembrolizumab

Pfizer

Phase 3

257

León, Benito Juárez, Monterrey, Mexico City, Puebla City

2021-01-15

Active, closed

Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)

NCT04634877Endometrial Neoplasms

DrugsPlatinol-AQ·Keytruda·Docetaxel·Paclitaxel

Merck Sharp & Dohme LLC

Phase 3

990

La Paz, Tuxtla Gutiérrez, Mexico City, Monterrey

2021-01-10

Active, closed

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

NCT04534205Unresectable Head and Neck Squamous Cell Carcinoma, Metastatic Head and Neck Cancer, Recurrent Head and Neck Cancer

DrugPembrolizumab

BioNTech SE

Phase 2/3

358

Tuxtla Gutiérrez, Chihuahua City, Guadalajara, Mexico City, Monterrey, Oaxaca City, Veracruz, Yucatán

2021-01-07

Active, closed

A Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL

NCT04521231B Cell Precursor Acute Lymphoblastic Leukemia

DrugBlinatumomab

Amgen

Phase 1/2

181

Monterrey, Querétaro

2021-01-04

Active, closed

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

NCT04607421Neoplasms

DrugsEncorafenib·Zirabev·Erbitux·Xeloda

Pfizer

Phase 3

841

Monterrey, Oaxaca City

2020-12-21

Active, closed

Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer With or Without Actionable Genomic Alterations (TROPION-LUNG01)

NCT04656652Non-small Cell Lung Cancer

DrugsDato-DXd·Docetaxel

Daiichi Sankyo

Phase 3

605

Aguascalientes, Guadalajara, Mexico City, Monterrey

2020-12-21

Active, closed

A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer

NCT04556773Metastatic Breast Cancer

DrugsCapivasertib·Anastrozole·Trastuzumab deruxtecan·Fulvestrant

AstraZeneca

Phase 1

138

Monterrey

2020-12-17

Active, closed

Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-small Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy

NCT04655976Lung Cancer, Non-Small Cell

DrugsCobolimab·Dostarlimab·Docetaxel

GlaxoSmithKline

Phase 2/3

758

Guadajalara, Mexico City, Monterrey, Puebla Puebla

2020-12-08

Active, closed

Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)

NCT04624204Small Cell Lung Cancer

DrugsOlaparib·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

672

Guadalajara, Monterrey

2020-12-08

Active, closed

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

NCT04658862Urinary Bladder Neoplasms

DrugsTAR-200·Cetrelimab·Gemcitabine·Cisplatin

Janssen Research & Development, LLC

Phase 3

518

Guadalajara, Juchitán de Zaragoza, León, Mexico City, Monterrey, Morelia, Oaxaca City, San Luis Potosí City

2020-12-07

Active, closed

A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

NCT04622319HER2-Positive Primary Breast Cancer, Residual Invasive Breast Cancer

DrugsTrastuzumab emtansine·Trastuzumab deruxtecan

Daiichi Sankyo

Phase 3

1,600

Torreón, Guadalajara, Monterrey

2020-12-04

Recruiting

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

NCT04613596Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer

DrugsAdagrasib·Pembrolizumab

Mirati Therapeutics Inc.

Phase 2/3

626

Guadalajara, Mexico City, Monterrey

2020-12-02

Active, closed

A Study of Adding Apalutamide to Radiotherapy and LHRH Agonist in High-Risk Patients With Hormone-Sensitive Prostate Cancer

NCT04557059Prostatic Neoplasms

DrugsLhrha·Apalutamide

Janssen Pharmaceutica N.V., Belgium

Phase 3

691

Durango, León, Monterrey, Naucalpan, Oaxaca City, Puebla City, Querétaro

2020-11-12

Recruiting

Autologous Platelet-rich Plasma (APRP) in the Treatment of Neurotrophic Keratopathy

NCT04604834Neurotrophic Keratopathy

Universidad Autonoma de Nuevo Leon

Not applicable

Monterrey

2020-11-01

Active, closed

Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer

NCT04464226Cancer

DrugDarolutamide

Bayer

Phase 3

774

Monterrey, Querétaro City

2020-10-20

Active, closed

Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC

NCT04446117Metastatic Prostate Cancer, Prostate Adenocarcinoma

DrugsZytiga·Xtandi·Abiraterone·Abiraterone acetate

Exelixis

Phase 3

575

Tuxtla Gutiérrez, León, Guadalajara, Zapopan, Mexico City, Monterrey, Querétaro City, San Luis Potosí City

2020-10-19

Active, closed

Study of Durvalumab Versus Placebo in Combination With Definitive Chemoradiation Therapy in Patient With ESCC

NCT04550260Esophageal Squamous Cell Carcinoma

DrugsFluorouracil·Durvalumab·Capecitabine·Cisplatin

AstraZeneca

Phase 3

640

Chihuahua City, Cuernavaca, Mérida, Monterrey, Veracruz

2020-10-19

Active, closed

A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions

NCT04538664Carcinoma, Non-Small-Cell Lung

DrugsAmivantamab·Pemetrexed·Carboplatin

Janssen Research & Development, LLC

Phase 3

308

Chihuahua City, Guadalajara, Mexico City, México, Monterrey, Naucalpan

2020-10-13

Active, closed

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

NCT04546009Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer

DrugsGiredestrant·Palbociclib·Letrozole

Hoffmann-La Roche

Phase 3

992

CD Mexico, Mexico City, Monterrey, Oaxaca City, San Luis Potosí City, Morelia, Veracruz

2020-10-09

Active, closed

A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312)

NCT04529772Diffuse Large B-Cell Lymphoma

DrugsAcalabrutinib·Vincristine·Doxorubicin·Prednisone

Acerta Pharma BV

Phase 3

611

Chihuahua City, Monterrey

2020-10-08

Active, closed

A Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors

NCT04434092Paroxysmal Nocturnal Hemoglobinuria

DrugsCrovalimab·Eculizumab

Hoffmann-La Roche

Phase 3

210

Mexico City, Monterrey

2020-10-08

Active, closed

A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

NCT04487080Carcinoma, Non-Small-Cell Lung

DrugsLazertinib·Amivantamab·Osimertinib

Janssen Research & Development, LLC

Phase 3

1,074

Guadalajara, León, Mexico City, México, Monterrey, Naucalpan

2020-09-30

Active, closed

A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-MutatedProstatic Neoplasms (mCSPC)

NCT04497844Prostatic Neoplasms

DrugsAbiraterone acetate·Prednisone

Janssen Research & Development, LLC

Phase 3

696

Durango, León, Mexico City, Monterrey, Naucalpan, Oaxaca City, Zapopan

2020-09-23

Recruiting

Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors

NCT04557449Liposarcoma, Prostate Cancer, Advanced Breast Cancer, NSCLC (Non-small Cell Lung Cancer)

DrugAtirmociclib

Pfizer

Phase 2

430

Mexico City, Monterrey, Oaxaca City

2020-09-23

Active, closed

Study to Evaluate Loncastuximab Tesirine With Rituximab Versus Immunochemotherapy in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

NCT04384484Relapsed Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma

DrugsLoncastuximab Tesirine·Rituximab·Oxaliplatin·Gemcitabine

ADC Therapeutics S.A.

Phase 3

440

Guadalajara, Cuernavaca, Monterrey, Huixquilucan, Mexico City

2020-09-16

Active, closed

Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery

NCT04498117Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Ovarian Cancer, Ovarian Serous Adenocarcinoma

DrugsOregovomab·Paraplatin·Taxol·Paclitaxel

CanariaBio Inc.

Phase 3

615

Orizaba, La Paz, Monterrey, Querétaro, San Luis Potosí City

2020-08-25

Active, closed

A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With ISN/RPS 2003 Class III or IV Lupus Nephritis

NCT04221477Lupus Nephritis

DrugsDiphenhydramine·Acetaminophen·Methylprednisolone·Obinutuzumab

Hoffmann-La Roche

Phase 3

271

Mexico City, Monterrey

2020-08-10

Active, closed

Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer

NCT04494425Advanced or Metastatic Breast Cancer

DrugsTrastuzumab deruxtecan·Nab-paclitaxel·Capecitabine·Paclitaxel

AstraZeneca

Phase 3

866

Alc. Cuauhtémoc, Guadalajara Jalisco, Guadalajra, Mexico City, México, Monterrey, Nuevo León

2020-07-24

Active, closed

Linerixibat Long-term Safety, and Tolerability Study

NCT04167358Cholestasis

GlaxoSmithKline

Phase 3

242

Mexico City, Monterrey

2020-07-14

Active, closed

Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency

NCT04493853Hormone-Sensitive Prostate Cancer

DrugsZytiga·Capivasertib·Abiraterone acetate

AstraZeneca

Phase 3

1,012

Culiacán, Guadalajara, Mexico City, Monterrey

2020-07-13

Active, closed

Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)

NCT04380636Lung Neoplasms, Carcinoma, Non-Small-Cell Lung

DrugsParaplatin·Taxol·Olaparib·Etoposide

Merck Sharp & Dohme LLC

Phase 3

870

Guadalajara, Monterrey, Orizaba, Tlalpan

2020-07-06

Active, closed

Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

NCT04273945Pulmonary Arterial Hypertension

DrugMacitentan

Actelion

Phase 3

935

Guadalajara, Mexico City, México, Monterrey, Morelia

2020-06-30

Active, closed

A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

NCT04232553Crohn's Disease

DrugMirikizumab

Eli Lilly and Company

Phase 3

996

Chihuahua City, Monterrey, San Luis Potosí City

2020-06-22

Active, closed

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

NCT04269200Endometrial Neoplasms

DrugsOlaparib·Durvalumab·Paclitaxel·Carboplatin

AstraZeneca

Phase 3

805

Aguascalientes, México, Monterrey, Oaxaca City, Querétaro, San Luis Potosí City, Veracruz

2020-05-05

Active, closed

A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA)

NCT04088396Systemic Juvenile Idiopathic Arthritis

DrugsBaricitinib·Tocilizumab

Eli Lilly and Company

Phase 3

Chihuahua City, Durango, Guadalajara, México, Monterrey

2020-02-12

Active, closed

A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension

NCT04175600Hypertension, Pulmonary

DrugSelexipag

Actelion

Phase 3

138

Guadalajara, México, Monterrey

2020-01-16

Active, closed

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors

NCT04082429Haemophilia A Without Inhibitors, Haemophilia B Without Inhibitors

DrugConcizumab

Novo Nordisk A/S

Phase 3

156

Monterrey

2019-11-13

Active, closed

A Study of Neoadjuvant Chemotherapy Plus Nivolumab Versus Neoadjuvant Chemotherapy Plus Placebo, Followed by Surgical Removal and Adjuvant Treatment With Nivolumab or Placebo for Participants With Surgically Removable Early Stage Non-small Cell Lung Cancer

NCT04025879Carcinoma, Non-Small-Cell Lung

DrugsOpdivo·Pemetrexed·Nivolumab·Docetaxel

Bristol-Myers Squibb

Phase 3

461

Chihuahua City, Guadalajara, Monterrey

2019-11-05

Active, closed

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitors

NCT04083781Haemophilia A With Inhibitors, Haemophilia B With Inhibitors

DrugConcizumab

Novo Nordisk A/S

Phase 3

134

Monterrey

2019-10-21

By invitation

A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

NCT03683186PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension

United Therapeutics

Phase 3

1,000

Guadalajara, Mexico City, Monterrey

2019-09-23

Active, closed

An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial

NCT03844048Chronic Lymphocytic Leukemia, Acute Myeloid Leukemia, Multiple Myeloma, Non-Hodgkin's Lymphoma

DrugsVenclexta·Venetoclax

AbbVie

Phase 3

165

Morelia, Monterrey

2019-09-06

Active, closed

An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis

NCT03950232Ulcerative Colitis

DrugEtrasimod

Pfizer

Phase 3

896

Chihuahua City, Guadalajara, Monterrey, Veracruz, Irapuato

2019-09-05

Active, closed

Observational Evaluation of Atopic Dermatitis in Pediatric Patients

NCT03687359Dermatitis Atopic

Sanofi

Observational

1,860

Cuernavaca, Monterrey, México, Puebla City, Tlalnepantla

2019-08-15

Recruiting

Pan Tumor Rollover Study

NCT03899155Cancer

DrugsRucaparib·Sunitinib·Trametinib·Relatlimab

Bristol-Myers Squibb

Phase 2

1,500

León, Zapopan, Cuauhtémoc, Tlalpan, Morelia, Monterrey, Querétaro City, Mexico City

2019-08-09

Active, closed

Perioperative Pembrolizumab (MK-3475) Plus Cystectomy or Perioperative Pembrolizumab Plus Enfortumab Vedotin Plus Cystectomy Versus Cystectomy Alone in Participants Who Are Cisplatin-ineligible or Decline Cisplatin With Muscle-invasive Bladder Cancer (MK-3475-905/KEYNOTE-905/EV-303)

NCT03924895Urinary Bladder Cancer, Muscle-invasive

DrugsEnfortumab Vedotin·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

595

Monterrey, Aguascalientes, Chihuahua City, Metepec, Mexico City

2019-07-24

Active, closed

Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC

NCT03997123Triple Negative Breast Neoplasms

DrugsCapivasertib·Paclitaxel

AstraZeneca

Phase 3

923

Aguascalientes, Estado de México, Guadalajara, México, Monterrey, Tuxtla Gutiérrez

2019-06-25

Active, closed

Study of Cabozantinib in Combination With Nivolumab and Ipilimumab in Patients With Previously Untreated Advanced or Metastatic Renal Cell Carcinoma

NCT03937219Renal Cell Carcinoma

DrugsCabozantinib·Yervoy·Ipilimumab·Opdivo

Exelixis

Phase 3

855

Aguascalientes, León, Zapopan, Monterrey, Oaxaca City, Mexico City, Querétaro

2019-06-25

Active, closed

A Study of Nivolumab Combined With Ipilimumab Versus Nivolumab Alone in Participants With Advanced Kidney Cancer

NCT03873402Renal Cell Carcinoma

DrugsYervoy·Ipilimumab·Opdivo·Nivolumab

Bristol-Myers Squibb

Phase 3

437

Mexico City, Monterrey, Chihuahua City, Querétaro

2019-06-21

Recruiting

Efficacy and Safety of Cariprazine in the Treatment of Adolescent Participants (13 to 17 Years of Age) With Schizophrenia

NCT03817502Schizophrenia

DrugCariprazine

Gedeon Richter Plc.

Phase 3

330

Culiacán, Durango, Guadalajara, Guanajuato City, Mérida, Monterrey, San Luis Potosí City

2019-06-06

Active, closed

Effisayil™ ON: A Study to Test Long-term Treatment With Spesolimab in People With Generalized Pustular Psoriasis Who Took Part in a Previous Study

NCT03886246Generalized Pustular Psoriasis

DrugSpesolimab

LEO Pharma

Phase 2

131

Monterrey

2019-05-29

Active, closed

A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes

NCT03811561Diabetes Mellitus, Type 2