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Trackers› Clinical trials› Italy
Clinical trial register · Italy

Clinical Trials in Italy

Every study on the ClinicalTrials.gov registry that lists a site in Italy and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 6779 matching records held by the registry are in this view. Synced 10 Nov 2026, 03:19 UTC
6779
Studies in scope
all four open statuses
4070
Recruiting now
open to new participants
1013
Lead sponsors
across recruiting studies
Top sites
Milan 2847 Bologna 1281 Roma 1263 Naples 980 Rome 966
Narrow the register
Recruitment status
Phase
Lead sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS363 IRCCS Azienda Ospedaliero-Universitaria di Bologna276 AstraZeneca180 IRCCS San Raffaele156 Novartis Pharmaceuticals131 Fondazione IRCCS Policlinico San Matteo di Pavia119 Merck Sharp & Dohme LLC116 Istituto Ortopedico Rizzoli108 Hoffmann-La Roche106 Janssen Research & Development, LLC82 AbbVie77 European Institute of Oncology74 Bristol-Myers Squibb74 Eli Lilly and Company74 Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico63 Sanofi63 Istituti Clinici Scientifici Maugeri SpA59 Pfizer56 GlaxoSmithKline49 Fondazione Don Carlo Gnocchi ETS48 Istituto Clinico Humanitas47 Mario Negri Institute for Pharmacological Research46 I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio45 Istituto Auxologico Italiano45 Meyer Children's Hospital IRCCS43 Show all 1439
Site location
Milan2847 Bologna1281 Roma1263 Naples980 Rome966 Florence788 Pavia571 Brescia523 Padova503 Genova491 Rozzano472 Bari451 Pisa399 Bergamo378 Meldola355 Catania340 Ancona298 Verona282 Monza281 Palermo276 Torino275 Modena259 Aviano201 Messina168 Alessandria164 Show all 491
All 491 locations
Target enrolment
to

Trials in this register

6779 of 6779 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
Sites in Italy
Start
Recruiting
Mario Negri Institute for Pharmacological Research
Observational
300,000
Milan, Catania, Orbassano, Pozzuoli, Torino, Vercelli
2024-10-01
Recruiting
Scientific Institute San Raffaele
Not applicable
2,840
Milan
2024-10-01
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
30
Bologna
2024-10-01
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
60
Rome
2024-10-01
Recruiting
A Multifocal tDCS-EEG Protocol for Improving Symptoms of Mild Cognitive Impairment and Early Dementia
NCT06668610Mild Cognitive Impairment (MCI), Dementia, Alzheimer Disease, Early Onset, Alzheimer Disease
University of Campania Luigi Vanvitelli
Not applicable
50
Caserta
2024-10-01
Not yet open
Azienda Ospedaliero-Universitaria Careggi
Not applicable
2
Florence
2024-10
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
700
Milan, Rome
2024-10
Not yet open
Transcatheter Treatment of Tricuspid Valve Regurgitation
NCT06093828Symptomatic Severe Tricuspid Regurgitation
TriFlo Cardiovascular, Inc.
Not applicable
40
Castel Volturno, Rozzano, San Donato Milanese, Roma
2024-10
Not yet open
Chemoreflex Sensitivity in HFpEF
NCT06309537Heart Failure With Preserved Ejection Fraction
Istituto Auxologico Italiano
Observational
60
Milan
2024-10
By invitation
Open-Label Extension Study to Assess GLM101 in PMM2-CDG Patients
NCT06657859Pmm2-CDG, Phosphomannomutase 2 Deficiency
Glycomine, Inc.
Phase 2
90
Catania, Pisa
2024-09-30
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,000
Roma
2024-09-30
Recruiting
Scientific Institute San Raffaele
Observational
140
Rozzano, Milan, Rome
2024-09-30
Active, closed
Aortic Dissection fAlse enlarGement radIomics predictiOn
NCT07117825Dissection, Aortic Diseases, Aortic Dissection
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
500
Roma
2024-09-30
Active, closed
Regeneron Pharmaceuticals
Phase 2
19
Ferrara
2024-09-30
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
50
Bologna
2024-09-30
By invitation
The Italian Registry of Patients With Chronic Obstructive Pulmonary Disease
NCT06652776COPD, COPD Exacerbation Acute, Comorbid Chronic Lung Disease on Heart Failure, Mortality
University of Milan
Observational
10,000
Milan
2024-09-30
Not yet open
NBI for Early Diagnosis of OPMD/OSCC
NCT06438939Oral Squamous Cell Carcinoma, Oral Potentially Malignant Disorder
Cardarelli Hospital
Not applicable
480
Naples
2024-09-30
Recruiting
Scientific Institute San Raffaele
Observational
386
Rozzano, Milan
2024-09-30
By invitation
Sanofi
Phase 2
900
Rome
2024-09-30
Recruiting
GlaxoSmithKline
Phase 1
845
Milan, Naples, Roma, Verona
2024-09-30
Active, closed
Hannover Medical School
Not applicable
20
Milan
2024-09-30
Active, closed
AstraZeneca
Phase 3
310
Florence, Orbassano, Roma, Verona
2024-09-30
Recruiting
Diagnosis and Treatment of Late Neurological Ischemic Deficit in Patients Suffering From Subarachnoid Hemorrhage.
NCT06804421Aneurysmal Subarachnoid Haemorrhage, Delayed Ischemic Neurological Deficit
Fondazione IRCCS San Gerardo dei Tintori
Observational
1,400
Bergamo, Bologna, Brescia, San Fermo della Battaglia, Cremona, Florence, Genova, Lecco
2024-09-28
Active, closed
Stemline Therapeutics, Inc.
Phase 3
4,556
San Giovanni Rotondo, Monserrato, Viagrande, Bologna, Meldola, Monza, Frattamaggiore, Aviano
2024-09-27
Recruiting
GlaxoSmithKline
Phase 2
393
Bergamo, Bologna, Messina, Milan, Padova, Roma
2024-09-27
Active, closed
Boehringer Ingelheim
Phase 3
1,666
Brescia, Catania, Florence, Foggia, Forlì, Milan, Modena, Monza
2024-09-26
Recruiting
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Phase 3
406
Salerno, Rome, Brescia, Milan, Ponderano (Biella), Roma
2024-09-26
Recruiting
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Phase 1/2
73
Milan
2024-09-26
Recruiting
Regina Elena Cancer Institute
Not applicable
98
Rome
2024-09-26
Recruiting
Evaluation of Clinical and Radiological Outcomes in Patients Undergoing Fixation of Osteochondral Fragments With Reasorbable Screws in the Knee Joint
NCT06462040Osteochondral Defect, Osteochondritis Dissecans, Osteochondral Fracture, Osteochondral Fracture of Patella
Istituto Ortopedico Rizzoli
Observational
100
Bologna
2024-09-25
Active, closed
Longboard Pharmaceuticals
Phase 3
108
Florence, Genoa, Pavia, Rome, Verona
2024-09-25
Active, closed
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Observational
210
Milan
2024-09-25
Recruiting
Pfizer
Phase 2
48
Florence
2024-09-25
Active, closed
Genmab
Phase 3
699
Ancona, Brescia, Cagliari, Meldola, Milan, Naples, Rome, Rozzano
2024-09-25
Active, closed
A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy
NCT06481891Obstructive Cardiomyopathy, Hypertrophic, Non-obstructive Hypertrophic Cardiomyopathy
DrugSotagliflozin
Lexicon Pharmaceuticals
Phase 3
500
Arezzo, Brescia, Naples
2024-09-24
Active, closed
argenx
Phase 1
15
Milan
2024-09-24
Recruiting
Costantino Errani
Observational
250
Bologna
2024-09-23
Recruiting
GALENOS 1 in Head and Neck, Lung, and Rectal Cancer Patients
NCT07511413Head and Neck Squamous Cell Carcinoma, Locally Advanced Rectal Cancer, Lung Cancer
Fondazione del Piemonte per l'Oncologia
Observational
110
Candiolo
2024-09-23
Recruiting
Istituto Oncologico Veneto IRCCS
Phase 2
104
Meldola, Messina, Bagno a Ripoli, Aviano, Rozzano, Bari, Bologna, Florence
2024-09-23
Active, closed
Hoffmann-La Roche
Phase 3
338
Bari, Parma, Rome, Genoa, Sassari, Florence, Pisa, Padova
2024-09-23
Recruiting
Development of Innovative Preclinical Ex Vivo Models for the Study of Sarcomas and Metastases From Solid Tumors
NCT07112989Bone and Soft Tissue Tumors, Bone Metastases From Solid Tumors, Lung Metastases
Istituto Ortopedico Rizzoli
Observational
125
Bologna
2024-09-23
Active, closed
Meyer Children's Hospital IRCCS
Not applicable
100
Florence
2024-09-23
Recruiting
Negative Antiphospholipid Syndrome: a Multicentric Study
NCT06373003Antiphospholipid Syndrome, Seronegative Antiphospholipid Syndrome
Italian Society for Rheumatology
Observational
105
Roma
2024-09-21
Active, closed
Cerevance
Phase 3
330
Cassino, Padova, Rome
2024-09-20
Recruiting
Merck Sharp & Dohme LLC
Phase 1/2
160
Meldola, Milan, Pisa
2024-09-20
Recruiting
INOCA-NA a Local Prospective Registry
NCT06588244Ischemia, Myocardial, Non-Obstructive Coronary Atherosclerosis, Microcirculatory Status, Coronary Microvascular Dysfunction (CMD)
Federico II University
Observational
250
Naples
2024-09-19
Recruiting
Janssen Research & Development, LLC
Phase 2/3
274
Ferrara, Milan, Naples, Roma
2024-09-19
Recruiting
IRCCS Policlinico S. Donato
Observational
800
San Donato Milanese
2024-09-18
Active, closed
argenx
Phase 3
141
Bergamo, Bologna, Milan, Naples, Roma
2024-09-18
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
2,700
Roma
2024-09-18
Recruiting
AstraZeneca
Phase 1/2
174
Bologna, Milan
2024-09-18
Active, closed
Regeneron Pharmaceuticals
Phase 2
151
Cuneo, Ferrara, Milan, Naples, Novara, Pisa, Rome, Taormina
2024-09-18
Active, closed
Amgen
Phase 1
49
Alessandria, Milan, Rozzano (MI), Verona
2024-09-17
Active, closed
GlaxoSmithKline
Phase 2
153
Genova, Milan, Naples, Roma, Sassari
2024-09-17
Recruiting
Fondazione IRCCS Policlinico San Matteo di Pavia
Observational
60
Pavia
2024-09-17
Active, closed
Dianthus Therapeutics
Phase 2
46
Rome
2024-09-17
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Roma, Rome
2024-09-17
Recruiting
European Registry of Next Generation Imaging in Advanced Prostate Cancer
NCT06866782Prostate Cancer, Advanced Prostate Cancer, Metastatic Prostate Cancer (mPC)
Fundacio Puigvert
Observational
600
Bologna, Florence, Milan
2024-09-17
Active, closed
Hoffmann-La Roche
Phase 3
400
Matera, Naples, Rome, Pavia, Rho
2024-09-17
Recruiting
Università degli Studi di Trento
Not applicable
60
Rovereto
2024-09-17
Active, closed
Novo Nordisk A/S
Phase 4
500
Florence, Milan, Roma, Trieste, Verona
2024-09-17
Active, closed
Zenas BioPharma (USA), LLC
Phase 2
190
Ferrara, Genova, Milan, Pisa, Roma, Torino, Verona
2024-09-17
Recruiting
Regeneron Pharmaceuticals
Phase 2
116
Meldola, Genoa, Milan, Alessandria, Ascoli Piceno, Pavia, Ravenna
2024-09-16
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
100
Bologna
2024-09-15
Recruiting
Heart Care Foundation
Observational
5,000
Montevarchi, Acquaviva delle Fonti, Altamura, Bari, Brescia, Monserrato, Catania, Campobasso
2024-09-15
Recruiting
Advanced Imaging Holistic Omics Biobank
NCT06523270Oncologic Disorders, Neurologic Disorder, Pulmonary Disease, Cardiovascular Diseases
IRCCS San Raffaele
Observational
50,000
Milan
2024-09-15
Not yet open
UNDERSTANDING the RAREST GYNECOLOGICAL CANCERS: a MULTI -OMICS PLATFORM for IMPROVED PATIENTS MANAGEMENT
NCT06582108Uterine Sarcoma, Vulvar Cancer, Non Epithelial Ovarian Cancers (NEOC)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
190
Rome
2024-09-15
Recruiting
Consorzio Oncotech
Observational
300
Bari, Bologna, Cuneo, Catania, Meldola, Florence, Genova, Monza
2024-09-13
Active, closed
MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
NCT06586515Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer, Colorectal Cancer
DrugsLeucovorin·Irinotecan·Cetuximab·Adrucil
Eli Lilly and Company
Phase 1
630
Naples, Roma, Verona
2024-09-12
Recruiting
University of Turin, Italy
Not applicable
20
Turin
2024-09-12
Active, closed
Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab)
NCT06430866Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)
DrugsABP 234·Pembrolizumab
Amgen
Phase 3
163
Cona, Cuneo, Florence, Lucca, Monserrato, Naples, Peschiera del Garda, Ravenna
2024-09-12
Recruiting
Speed-up the Diagnosis and Evaluation of anoMalous Coronary ARTery From the Aorta
NCT06705751AAOCA, ACAOS, Anomalous Aortic Origin of the Coronary Artery (AAOCA), Anomalous Coronary Artery Arising From the Opposite Sinus
IRCCS Policlinico S. Donato
Not applicable
38
San Donato Milanese
2024-09-12
Recruiting
GlaxoSmithKline
Phase 3
440
Ancona, Milan, Modena, Naples, Padova, Palermo, Pavia, Pisa
2024-09-11
Active, closed
A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis
NCT06431373Uveitis, Posterior, Uveitis, Intermediate, Uveitis
Priovant Therapeutics, Inc.
Phase 3
371
Perugia, Milan, Reggio Emilia, Roma
2024-09-11
Recruiting
A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis
NCT06559150Non-cystic Fibrosis Bronchiectasis
Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA
Phase 2
284
Monza, Rozzano, Catania, Bologna, Pavia
2024-09-11
Recruiting
Regeneron Pharmaceuticals
Phase 1/2
130
Florence, Milan, Rozzano, Vicenza
2024-09-11
Recruiting
Fondazione Don Carlo Gnocchi ETS
Observational
312,800
Florence
2024-09-10
Recruiting
Olfactory Testing in Perinatal Asphyxia: Enhancing Risk Assessment
NCT06744244Mild Birth Asphyxia, Moderate Birth Asphyxia
University of Parma
Observational
30
Parma
2024-09-10
Active, closed
Pierre Fabre Medicament
Observational
368
Monza
2024-09-10
Active, closed
GCP-Service International West GmbH
Phase 2
41
Ancona, Bari, Candiolo, Florence, Milan, Reggio Calabria
2024-09-10
Recruiting
Prevention ICONA Dedicated Ensemble
NCT07186244PrEP, PrEP Adherence Monitoring, HIV, HIV -1 Infection
Fondazione ICONA
Observational
5,000
Chieti, Pescara, Bari, Foggia, Potenza, Caserta, Naples, Bologna
2024-09-09
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
260
Roma
2024-09-09
Active, closed
Evaluation of the Effect of Lomitapide Treatment on Major Adverse Cardiovascular Events (MACE) in Patients With Homozygous Familial Hypercholesterolemia
NCT06832371Homozygous Familial Hypercholesterolemia (HoFH), Major Adverse Cardiovascular Events (MACE), Dyslipidemia
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi)
Observational
73
Catanzaro, Caserta, Naples, Bologna, Ferrara, Modena, Genova, Catania
2024-09-09
Recruiting
Blood Extracellular Vesicles as Predictive Recovery Biomarker After Stroke and Brain Injury
NCT06871800Stroke, Vascular Severe Brain Injury, Rehabilitation
Fondazione Don Carlo Gnocchi ETS
Observational
60
Florence, Milan, Torino
2024-09-09
Active, closed
Pregnancy and Lactation- Associated Osteoporosis
NCT07031557Osteoporosis and Fracture Risk in Pregnant Women
Parma University Hospital
Observational
1,230
Parma
2024-09-09
Recruiting
Neurodegenerative Diseases Progression Markers (MARKERS-NDD)
NCT06596746Neurodegenerative Diseases, Parkinson Disease, Synucleinopathies, Lewy Body Disease
Casa di Cura San Raffaele Cassino
Observational
600
Cassino
2024-09-09
Active, closed
Amgen
Phase 3
315
Cona, Cremona, Milan, Naples, Ravenna, Sondrio, Terni
2024-09-09
Recruiting
Laura Deborah Locati
Not applicable
60
Naples, Pavia, Sassari
2024-09-09
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
500
Roma
2024-09-09
By invitation
Regione del Veneto - AULSS n. 7 Pedemontana
Not applicable
45
Bassano
2024-09-06
Recruiting
Valerio Nardone
Observational
1,000
Barletta, Campobasso, Lecce, Naples, Potenza, Roma
2024-09-06
Recruiting
A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.
NCT06476808High-grade Serous Ovarian Carcinoma (HGSOC), Uterine Serous Carcinoma (USC), Non-small Cell Lung Cancer (NSCLC)
Bristol-Myers Squibb
Phase 1
240
Milan
2024-09-06
Recruiting
European Institute of Oncology
Not applicable
82
Milan
2024-09-06
By invitation
Federico II University
Not applicable
150
Naples
2024-09-06
Recruiting
Angela Toss
Observational
100
Genova, Milan, Modena, Padova, Roma
2024-09-05
Recruiting
SPAGO: Sirolimus Paclitaxel Angiographic Gain Objective
NCT06373601Coronary Artery Disease, Stenosis Coronary, Coronary Artery Lesion, Percutaneous Coronary Intervention
Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS
Not applicable
140
Mercogliano, Bergamo, Brescia, Ferrara, Milan, Rozzano, Naples, Orbassano
2024-09-05
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
20
Rome
2024-09-04
Recruiting
Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus
NCT07100613Oral Lichen Planus, Oral Lichen Planus Related Stress, Oral Mucosal Disease, Oral Pain
DrugsResveratrol·Clobetasol
University of Palermo
Phase 2
45
Palermo
2024-09-04
Recruiting
AbbVie
Phase 2
590
Monserrato, San Giovanni Rotondo, Rozzano, Milan, Rome, Turin, Negrar, Catanzaro
2024-09-04
Active, closed
Novartis Pharmaceuticals
Phase 2
179
Alessandria, Ancona, Genova, Milan, Rozzano, Pescara, Pisa, Pavia
2024-09-04
Active, closed
Takeda
Phase 3
2,099
Rozzano, Catania, Florence
2024-09-04
Recruiting
Clinical-ultrasonographic Assessment of Pulmonary Emphysema
NCT06533371Emphysema, Pulmonary Emphysema
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
1,628
Acquaviva delle Fonti, Naples, Rome, Trento
2024-09-04
Recruiting
Study of Axial and Cognitive Symptoms and Biomarkers of Neurodegeneration in Brain-first and Body-first PD
NCT07187843Parkinson Disease, Parkinsonian Disorders, Brain Disease, Basal Ganglia Diseases
Azienda USL Reggio Emilia - IRCCS
Observational
150
Reggio Emilia
2024-09-04
Recruiting
Gossamer Bio USA, Inc.
Phase 3
330
Bologna, Naples, Pavia, Roma
2024-09-03
Recruiting
Recornea Srl
Not applicable
12
Roma
2024-09-03
By invitation
Giovanni Di Perri
Observational
200
Genova, Milan, Torino, Bari, Catania, Naples, Padova, Roma
2024-09-02
Recruiting
Ospedale Policlinico San Martino
Not applicable
80
Genova
2024-09-02
Active, closed
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
256
Milan
2024-09-01
Active, closed
PRIMA Project- Box for Heath and Tradition (B4HT)
NCT06719999Obesity and Obesity-related Medical Conditions
University of Bari
Not applicable
450
Bari
2024-09-01
Recruiting
Post-Extraction Healing: microRepair vs Chlorhexidine
NCT07555366Endodontic Issue, Periodontal Issues
University of Roma La Sapienza
Not applicable
30
Roma
2024-09-01
Recruiting
Arch Size Study for Anatomical Variations
NCT06235619Aortic Arch, Aneurysm, Dissection, Aortic
IRCCS San Raffaele
Observational
500
Milan
2024-09-01
Recruiting
Istituto Ortopedico Rizzoli
Not applicable
200
Bologna, Naples
2024-09-01
Recruiting
San Luigi Gonzaga Hospital
Not applicable
360
Aosta, Biella, Cuneo, Cona, Genova, Rivoli, Trapani, Orbassano
2024-09-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,000
Roma
2024-09-01
Recruiting
Istituto Giannina Gaslini
Observational
165
Catania, Genova, Milan
2024-09-01
Not yet open
In Vitro Models From Pediatric Brain Tumors
NCT06499636Glioma, Malignant, Ependymoma, Medulloblastoma
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
100
Roma
2024-09-01
Recruiting
European Institute of Oncology
Not applicable
60
Milan
2024-09-01
Not yet open
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
220
Roma
2024-09-01
Recruiting
Speech and Language Interventions for Italian People With PPA
NCT06739967Primary Progressive Aphasia(PPA)
Istituti Clinici Scientifici Maugeri SpA
Observational
30
Bari, Milan
2024-09-01
Recruiting
CRS Questionnaire Validation Project
NCT06970977Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps
The European Forum for Research and Education in Allergy and Airway Diseases
Observational
1,000
Roma
2024-09-01
Recruiting
IRCCS San Raffaele
Observational
123
Milan
2024-09-01
Recruiting
University of Eastern Piedmont
Not applicable
160
Novara
2024-09-01
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
24
Roma
2024-09-01
Active, closed
How Epigenetic Changes in hMLH1 Connect Lab Research With Diagnosis in Gastric Cancer
NCT06982768Gastrectomy for Gastric Cancer, Gastrectomy, MLH1 Gene Mutation, Gastric Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
245
Rome
2024-09-01
Not yet open
Armando Santoro, MD
Phase 1/2
86
Rozzano
2024-09
Recruiting
Post-Transplant Diabetes Outcomes Prediction
NCT07512804New Onset Diabetes After Transplantation
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
120
Roma
2024-08-31
Recruiting
ScATtEred Rare Disease Biobanks: a Model of Sample/Data Collection With susTainablE and Shared Criteria
NCT06782230Creation of an Italian Network of Biobanks of Rare Diseases
IRCCS Policlinico S. Donato
Observational
800
San Donato Milanese
2024-08-31
Active, closed
Servier Bio-Innovation LLC
Phase 1/2
48
Campania, Milan, Pisa, Rome, Verona
2024-08-31
Recruiting
Fondazione Don Carlo Gnocchi ETS
Observational
2,000
Milan
2024-08-31
Recruiting
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Not applicable
100
Milan
2024-08-31
Active, closed
Non-invasive Tests for Non-alcoholic Steato-hepatitis
NCT07502755NASH With Fibrosis, Diabete Type 2, Obesity
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
828
Roma
2024-08-31
Recruiting
Dr. Inge Winter
Phase 3
418
Brescia, Cagliari, Naples, Turin
2024-08-31
Recruiting
Study of Extracellular Vesicles (EV) in Patients Undergoing CAR-T Cell Therapies
NCT06554951CAR-T Cell Therapy, Extracellular Vesicles
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
100
Bologna
2024-08-31
Recruiting
IRCCS San Raffaele
Not applicable
30
Milan
2024-08-31
Active, closed
IRCCS SYNLAB SDN
Observational
80,000
Naples
2024-08-30
Active, closed
University of Messina
Observational
100
Messina
2024-08-30
Active, closed
Alpine Immune Sciences Inc, A Subsidiary of Vertex
Phase 3
605
Bari, Genova, Modena, Pavia, Rome
2024-08-30
Active, closed
Boehringer Ingelheim
Phase 3
8,371
Alessandria, Asti, Bari, Bergamo, Bologna, Cagliari, Chieri, Chieti
2024-08-30
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
60
Bologna
2024-08-30
Recruiting
Istituto Ortopedico Rizzoli
Observational
30
Bologna, Meldola
2024-08-30
Recruiting
Impact of Trans-catheter Aortic Valve Implantation on Renal Function
NCT07626710Aortic Valve Stenosis, Chronic Kidney Diseases, Renal Failure Acute Chronic
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,000
Roma
2024-08-30
Active, closed
Celgene
Phase 2
95
Rome, Rozzano, Bologna, Naples
2024-08-30
Recruiting
Ospedale San Raffaele
Observational
250
Milan
2024-08-30
Recruiting
Multidimensional Omics Analysis in Malignant Pleural Mesothelioma
NCT07561190Malignant Pleural Mesothelioma (MPM)
Azienda USL Reggio Emilia - IRCCS
Observational
300
Catania, Naples, Reggio Emilia, Roma
2024-08-30
Active, closed
Sanofi
Phase 2
229
Milan, Padua, Pisa
2024-08-29
Active, closed
Microbiotica Ltd
Phase 1
41
Milan, Naples, Rozzano
2024-08-28
Active, closed
Phase IIa Study Evaluating AZD7798 in Crohn's Disease
NCT06450197Moderate to Severe Crohn's Disease
DrugAZD7798
AstraZeneca
Phase 2
120
Milan, Roma, Rome
2024-08-28
Recruiting
Bayer
Phase 3
444
Lecce, Avellino, Bologna, Meldola, Aviano, Rome, Milan, Rozzano
2024-08-28
Active, closed
Gilead Sciences
Phase 3
640
Aviano, Florence, Lecco, Meldola, Milan, Padova, Pisa, Roma
2024-08-28
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
65
Bologna
2024-08-28
Active, closed
AstraZeneca
Phase 2
194
Genoa, Meldola, Milan, Naples, Orbassano, Perugia, Rozzano, Udine
2024-08-27
Active, closed
Zenas BioPharma (USA), LLC
Phase 2
93
Cefalù, Florence, Pozzilli, Roma
2024-08-26
Recruiting
Azienda Ospedaliero-Universitaria di Modena
Observational
100
Modena
2024-08-26
Recruiting
Observational Study of Venus P-Valve
NCT05835349Right Ventricular Outflow Tract Dysfunction
Venus MedTech (HangZhou) Inc.
Observational
200
Rome, Milan
2024-08-26
Active, closed
Kite, A Gilead Company
Phase 3
452
Milan, Bologna, Roma, Torino
2024-08-23
Recruiting
Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors
NCT06535607Sub-study 1 Cervical Cancer (Volrustomig Monotherapy), Sub-study 2 Head and Neck Squamous Cell Carcinoma (Volrustomig Monotherapy), Sub-study 3 Head and Neck Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy), Sub-study 4 Esophageal Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy)
DrugsVolrustomig·Adrucil·Paclitaxel·Cisplatin
AstraZeneca
Phase 2
257
Alessandria, Bergamo, Orbassano
2024-08-22
Recruiting
Abbott Structural Heart Device Registry
NCT06590467Heart Diseases, ASD - Atrial Septal Defect, VSD - Muscular Ventricular Septal Defect, PFO - Patent Foramen Ovale
Abbott Medical Devices
Observational
2,500
San Donato Milanese, Turin, Pisa
2024-08-21
Recruiting
Sanofi
Phase 3
160
Milan, Rozzano, Padua, Bologna
2024-08-21
Recruiting
Non-pharmacological Care for Depression in Cancer Patients Using VR and TMS
NCT06589544Depressive Symptoms, Quality of Life, Cognitive Impairment
University Hospital of Ferrara
Not applicable
100
Ferrara, Cagliari
2024-08-21
Recruiting
Colorado Prevention Center
Phase 3
2,600
Brescia, Germaneto
2024-08-20
Active, closed
argenx
Phase 2
3
Pisa, Rome
2024-08-20
Active, closed
Diakonhjemmet Hospital
Phase 4
387
Milan
2024-08-20
Recruiting
Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Observational
120
Alessandria
2024-08-19
Active, closed
AbbVie
Phase 3
699
Rome, Bologna
2024-08-19
Recruiting
Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)
NCT06371417Antiphospholipid Syndrome (APS), Bullous Pemphigoid (BP), Behçet's Syndrome (BS), Dermatomyositis (DM)
DrugRAY121
Chugai Pharmaceutical
Phase 1
144
Meldola, Milan, Torino
2024-08-19
Recruiting
Multicenter Retrospective Observational Study of Relapsed Diffuse Large B-Cell Lymphoma Presenting as Indolent Lymphoma
NCT06822829Diffuse Large B Cell Lymphoma (DLBCL), Indolent B-Cell Lymphomas, Indolent B Cell Lymphoma
Azienda USL Reggio Emilia - IRCCS
Observational
50
Reggio Emilia
2024-08-19
By invitation
Pericardial Fluid Analysis in Recurrent Pericarditis
NCT06293924Acute Pericarditis, Pericardial Effusion, Pericardial Disease, Pericardial Fluid Exudate
ASST Fatebenefratelli Sacco
Observational
432
Milan
2024-08-18
Recruiting
MiCrobiota-gut-brain Axis in Resistant Epilepsy
NCT07010445Gut Microbiota, Epilepsy, Drug-Resistant Epilepsy
Niguarda Hospital
Not applicable
120
Milan
2024-08-16
Recruiting
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
NCT06395103B-cell Acute Lymphoblastic Leukemia, Diffuse Large B-cell Lymphoma, Burkitt Lymphoma, Neuroblastoma
DrugZilovertamab vedotin
Merck Sharp & Dohme LLC
Phase 1/2
90
Milan, Rome, Torino
2024-08-16
Recruiting
Intra-Cellular Therapies, Inc.
Phase 2
370
Arzignano, Brescia, Cefalù, Tricase
2024-08-15
Active, closed
Novartis Pharmaceuticals
Phase 1/2
20
Meldola
2024-08-14
Active, closed
United Pharmaceuticals
Not applicable
70
Roma
2024-08-14
Recruiting
An Extension Study for Patients Previously Enrolled in Studies With Pelabresib
NCT06401356Hematologic Malignancy, Solid Tumor, Advanced Malignancies
DrugPelabresib
Novartis Pharmaceuticals
Phase 3
50
Florence, Varese, Novara
2024-08-13
Recruiting
Jazz Pharmaceuticals
Phase 3
550
Aviano, Bergamo, Bologna, Milan, Modena, Monza, Padova, Pavia
2024-08-13
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Not applicable
80
Bologna
2024-08-12
Recruiting
Fondazione Don Carlo Gnocchi ETS
Not applicable
596
Acerenza, Bari, Bergamo, Catania, Catanzaro, Crotone, Foggia, Genova
2024-08-12
Recruiting
AstraZeneca
Phase 3
620
Florence, Milan, Naples, Padova, Roma, Rozzano, Tricase
2024-08-12
Recruiting
University of Cagliari
Observational
80
Cagliari, Novedrate, Troina, Messina, Palermo
2024-08-08
Active, closed
Incyte Corporation
Phase 1
37
Bologna, Florence, Milan
2024-08-08
Active, closed
AbbVie
Phase 3
111
San Giovanni Rotondo, Rome, Messina, Milan
2024-08-08
Active, closed
Pfizer
Observational
450
Bari, Rozzano, Bologna, Catania, Roma, Rome
2024-08-07
Recruiting
VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease
NCT06257706Moderately to Severely Active Crohn's Disease, Crohn Disease, Disease Crohn
DrugVedolizumab
Alimentiv Inc.
Phase 4
304
San Giovanni Rotondo, Milan, Roma
2024-08-07
Active, closed
Servier Bio-Innovation LLC
Phase 1/2
102
Aviano, Meldola, Milan, Naples, Perugia, Roma, Rozzano
2024-08-07
Active, closed
EyeBiotech Ltd.
Phase 2/3
984
Bologna, Florence, Milan, Roma, Rome, Udine
2024-08-07
Recruiting
AstraZeneca
Phase 3
1,018
Bologna, Milan, Reggio Emilia
2024-08-07
Recruiting
Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)
NCT06445972Gastroesophageal Junction, Gastroesophageal Adenocarcinoma, Esophageal Neoplasms, Esophageal Cancer
DrugsPatritumab deruxtecan·Ramucirumab·Sacituzumab tirumotecan·Paclitaxel
Merck Sharp & Dohme LLC
Phase 1/2
210
Meldola, Milan, Pisa
2024-08-07
Recruiting
Regina Elena Cancer Institute
Observational
100
Rome
2024-08-06
Recruiting
intErnet-based iNterventions FOR Cardiac arrEst suRvivors
NCT06395558Cognitive Impairment, Depression, Anxiety, Cardiac Arrest, Quality of Life
Azienda Usl di Bologna
Not applicable
106
Bologna, Imola
2024-08-05
Recruiting
Istituto Ortopedico Rizzoli
Observational
120
Bologna, Catania
2024-08-05
Active, closed
Merck Sharp & Dohme LLC
Phase 3
3,000
Rome, Milan, Turin, Catania
2024-08-05
Recruiting
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Observational
50
Milan
2024-08-01
Not yet open
EC_ItaLynch: Mainstreaming the Diagnosis of Lynch Syndrome
NCT06501417Lynch Syndrome, Endometrial Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
600
Roma
2024-08-01
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
100
Bologna
2024-08-01
Recruiting
Dr. Inge Winter
Phase 4
418
Brescia, Cagliari, Naples, Turin
2024-08-01
Recruiting
University of Turin, Italy
Phase 3
420
Rozzano, Orbassano, Milan
2024-08-01
Recruiting
Comparison of Piezoelectric and Conventional Surgery for Germectomy of the Lower Third Molar
NCT06778590Tooth Disease, Piezoelectric Technique, Tooth Impacted, Tooth Extraction Status Nos
Amerigo Giudice
Not applicable
22
Catanzaro
2024-08-01
By invitation
Ospedale Policlinico San Martino
Observational
400
Genoa
2024-08-01
Active, closed
Fidia Farmaceutici s.p.a.
Not applicable
156
Bologna, Florence, Padova, Pavia, Roma, Torino, Milan
2024-08-01
Active, closed
GlaxoSmithKline
Phase 3
10,212
Negrar, Alessandria, Bari, Belluno, Ferrara, Naples, Palermo, Pessione - Chieri to
2024-08-01
Recruiting
AstraZeneca
Phase 3
788
Bergamo, Bologna, Milan, Modena, Naples, Padova, Reggio Emilia, Rome
2024-08-01
Active, closed
Bambino Gesù Hospital and Research Institute
Observational
14
Roma
2024-08-01
Recruiting
Fondazione Melanoma Onlus
Not applicable
20
Naples
2024-08-01
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
40
Bologna
2024-08-01
Recruiting
Continuous Glucose Monitoring in HIE
NCT06563687Hypoxic Ischemic Encephalopathy of Newborn, Hyperglycemia, Hypoglycemia
University of Campania Luigi Vanvitelli
Not applicable
70
Avellino, Naples
2024-08-01
Not yet open
Biological and Clinical Efficacy of Shingrix in Patients With CLL
NCT06364033Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, CLL-like MBL, Varicella-zoster Virus Reactivation
Gruppo Italiano Malattie EMatologiche dell'Adulto
Not applicable
312
Varese
2024-08
Recruiting
NovoCure GmbH
Phase 3
734
Alessandria, Bergamo, Ferrara, Meldola, Pesaro, Roma, Rome, Siena
2024-07-31
Not yet open
Istituto Clinico Humanitas
Observational
174
Rozzano
2024-07-31
Active, closed
Astellas Pharma Global Development, Inc.
Phase 3
982
Bologna, Genova, Milan, Mirano, Pavia, Reggio Emilia, Terni
2024-07-31
Active, closed
Novartis Pharmaceuticals
Phase 3
146
Bologna, Florence, Genova, Milan, Palermo, Roma, Orbassano
2024-07-31
By invitation
AOP Orphan Pharmaceuticals AG
Observational
110
Rome
2024-07-31
Recruiting
Istituto Giannina Gaslini
Observational
130
Genova, Lecce
2024-07-30
Active, closed
Novartis Pharmaceuticals
Observational
379
Ancona, L’Aquila, Bari, Bergamo, Chieti, Catania, Catanzaro, Cona
2024-07-30
By invitation
Biohaven Therapeutics Ltd.
Phase 2
660
Chieti, Catanzaro, Naples, Bologna, Rome, Genoa, Milan, Pavia
2024-07-30
Active, closed
Mario Negri Institute for Pharmacological Research
Observational
75
Bergamo
2024-07-30
Recruiting
ARCAGY/ GINECO GROUP
Phase 3
250
Alessandria, Bologna, Florence, Lecco, Milan, Venice
2024-07-30
Active, closed
Annexon, Inc.
Phase 3
659
Florence, Milan, Roma, Rome
2024-07-30
Active, closed
Università Vita-Salute San Raffaele
Not applicable
100
Milan, Verona
2024-07-29
Active, closed
International SBMA Project (KDA)
NCT07443449SBMA, Spinal and Bulbar Muscular Atrophy (SBMA)
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Observational
700
Milan
2024-07-29
Recruiting
Tissue Oximetry's Measurement in Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy
NCT06475261Oxygen Deficiency, Acute Kidney Injury, Ovarian Carcinoma
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
50
Rome
2024-07-27
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
160
Roma
2024-07-25
Recruiting
Marco Emilio Bianchi
Observational
70
Naples, Milan
2024-07-25
Recruiting
Niguarda Hospital
Observational
26
Milan
2024-07-25
Recruiting
A.O.U. Città della Salute e della Scienza
Observational
177
Turin
2024-07-25
Recruiting
CellFX® Nanosecond Pulsed Field Ablation (PFA) 360 Catheter Ablation System for Treatment of Atrial Fibrillation
NCT06696170Atrial Fibrillation Paroxysmal, Cardiac Ablation, Cardiac Arrhythmia
Pulse Biosciences, Inc.
Not applicable
60
Roma
2024-07-25
Recruiting
Janssen Research & Development, LLC
Phase 3
752
Brescia, Catania, Chieti, Genova, Monza, Pisa, Roma, Salerno
2024-07-25
Recruiting
Regina Elena Cancer Institute
Observational
150
Rome
2024-07-24
Recruiting
Azienda Socio Sanitaria della Brianza
Not applicable
40
Vimercate
2024-07-24
Recruiting
Regina Elena Cancer Institute
Observational
40
Rome
2024-07-24
Active, closed
Merck Sharp & Dohme LLC
Phase 3
686
Bologna, Milan, Monza, Rozzano, Turin, Brescia, Catania, Naples
2024-07-24
Active, closed
Ferrer Internacional S.A.
Phase 2
241
Bologna, Padova, Pisa, Roma, Salerno
2024-07-23
Recruiting
PulseSelect™ PFA Global Registry
NCT06393920Atrial Fibrillation
Medtronic Cardiac Ablation Solutions
Observational
1,950
Negrar, Ancona
2024-07-23
Recruiting
A Phase 1/2 Study of BGB-B2033, Alone or in Combination With Tislelizumab With or Without Bevacizumab, in Participants With Advanced or Metastatic Solid Tumors
NCT06427941Metastatic Hepatocellular Carcinoma, Local Advanced Hepatocellular Carcinoma, Alpha-fetoprotein (AFP)-Producing Gastric Cancer, Extragonadal Yolk Sac Tumors
DrugsBGB-B2033·Tislelizumab·Bevacizumab
BeOne Medicines
Phase 1/2
630
Naples, Padova, Roma, Rozzano
2024-07-23
Recruiting
TRAns-Femoral Access Intravascular Lithotripsy Comparison With PTA in TAVI
NCT05873842Trans-femoral TAVI With Calcified Ilio-femoral Arteries
Rede Optimus Hospitalar SA
Observational
50
Ancona, Mestre, Treviso, Verona, Vicenza
2024-07-22
Active, closed
MedSIR
Phase 2
165
Bergamo, Milan, Novara, Roma
2024-07-22
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
36
Rome
2024-07-20
Recruiting
IRCCS Fondazione Stella Maris
Observational
50
Pisa
2024-07-19
Recruiting
Jazz Pharmaceuticals
Phase 3
286
Monserrato, Candiolo, Genova, Milan, Naples, Padova, Pisa, Roma
2024-07-19
Active, closed
Celldex Therapeutics
Phase 3
976
Genova, Milan, Padova, Rozzano, Salerno, San Donato Milanese, Torino
2024-07-19
Recruiting
GlaxoSmithKline
Phase 3
150
Catania, Genova, Roma, Rozzano
2024-07-19
Recruiting
Real World Pediatric Oncology Rehabilitation in Italy ( ReWori )
NCT07368582Pediatric Cancer, Pediatric Cancer Patients, Pediatric Oncology, Rehabilitation
Associazione Italiana Ematologia Oncologia Pediatrica
Observational
249
Bergamo, Bologna, Bolzano, Bosisio Parini, Brindisi, Catania, Conegliano, Florence
2024-07-19
Recruiting
Digital diagnoSis of Cardiac sOUNd in peDiatric Patients [DI-SOUND Study]
NCT07542509Cardiac Disease, Auscultation of Heart, Machine Learning
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
1,000
Bologna, Milan, Roma, Naples
2024-07-18
Recruiting
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
Phase 2
385
Bologna, Brescia, Catanzaro, Milan, Padova, Pisa, Roma, Rozzano
2024-07-18
Recruiting
Amgen
Phase 3
450
Brescia, Castellana Grotte, Florence, Foggia, Genova, Meldola FC, Milan, Naples
2024-07-17
Active, closed
Merck Sharp & Dohme LLC
Phase 1/2
38
Milan, Naples
2024-07-17
Recruiting
Bristol-Myers Squibb
Phase 1/2
224
Milan, Padua, Verona
2024-07-17
Recruiting
Azienda USL Reggio Emilia - IRCCS
Not applicable
100
Pisa, Spilamberto
2024-07-17
Recruiting
University of Roma La Sapienza
Not applicable
40
Rome
2024-07-17
Active, closed
Vor Biopharma
Phase 3
191
San Giovanni Rotondo, Cefalù, Naples, Pavia, Rome
2024-07-17
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
36
Roma
2024-07-17
Recruiting
Caring for Frail Patients Through Vaccination
NCT06127563Vaccination Uptake
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
1,500
Rome
2024-07-17
Active, closed
Regeneron Pharmaceuticals
Phase 2
195
Naples, Ferrara, Piacenza, Florence, Livorno, Bergamo, Milan, Pesaro
2024-07-16
Active, closed
Merck Sharp & Dohme LLC
Phase 3
300
Florence, Alessandria, Bologna, Milan, Pavia, Roma, Varese
2024-07-16
Recruiting
Heidelberg University
Observational
4,000
Calambrone, Conegliano, Pisa, Roma
2024-07-16
Recruiting
University of Milano Bicocca
Not applicable
1,340
Monza
2024-07-16
Active, closed
Performance Study with the SiMoT System for in Vitro Diagnostic Tests
NCT06518967Non-interventional Analytical Performance Study on Left-over Samples
Centro di Innovazione Regionale in Single Molecule Digital Assay
Observational
50
Bari
2024-07-16
Recruiting
Istituto Auxologico Italiano
Observational
220
Milan
2024-07-15
Recruiting
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Not applicable
80
Bari
2024-07-14
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
500
Bologna
2024-07-13
Recruiting
Philogen S.p.A.
Phase 2
162
Naples
2024-07-12
Active, closed
A Study to Test the Effects and Safety of Riliprubart in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) for Which the Usual Treatments do Not Work
NCT06290128Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Polyneuropathy, Inflammatory Demyelinating, Chronic
DrugRiliprubart
Sanofi
Phase 3
109
Milan, Rozzano, Rome, Messina, Palermo, Pavia, Pisa
2024-07-12
Active, closed
Fidia Farmaceutici s.p.a.
Not applicable
72
Milan, Naples, Roma, Torino
2024-07-12
Active, closed
Celldex Therapeutics
Phase 3
963
Ancona, Mantua, Milan, Naples, Torino, Verona
2024-07-11
Recruiting
Fibrosis Lessens After Metabolic Surgery
NCT06374875Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Non-Alcoholic Fatty Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis (MASH), Liver Fibrosis
The Cleveland Clinic
Phase 4
120
Milan, Roma
2024-07-11
Recruiting
Case-Finding for Neurocognitive Disorders in Pavia
NCT06983119Dementia, Mild Cognitive Impairment
IRCCS National Neurological Institute "C. Mondino" Foundation
Not applicable
490
Pavia
2024-07-11
Recruiting
IRCCS Sacro Cuore Don Calabria di Negrar
Observational
402
Negrar
2024-07-10
Active, closed
GRIN Therapeutics, Inc.
Phase 1/2
30
Genoa, Florence, Roma
2024-07-10
Active, closed
UCB Biopharma SRL
Phase 3
70
Roma
2024-07-10
Recruiting
IRCCS San Raffaele
Observational
1,000
Milan
2024-07-10
Recruiting
A.O.U. Città della Salute e della Scienza
Observational
50
Turin
2024-07-10
Recruiting
Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 or 2 Systemic Treatment Regimens
NCT06127407Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
DrugIvosidenib
Servier Bio-Innovation LLC
Phase 3
156
Bologna, Milan, Orbassano, Padova, Palermo, Prato, Roma
2024-07-09
Recruiting
Polyspecific Antibodies in Lymphoproliferative T-cell Disorders
NCT06495723Peripheral T Cells Lymphoma (PTCL)
Xenothera SAS
Phase 1/2
54
Naples, Bologna, Milan
2024-07-09
Recruiting
AbbVie
Phase 3
40
Florence, Milan, Rome
2024-07-08
Recruiting
Fondazione IRCCS Policlinico San Matteo di Pavia
Not applicable
50
Pavia
2024-07-08
Recruiting
Lifestyle and Nutrition Evaluation in Physically Active People and Athletes
NCT06881745Dietary Habits, Nutritional Status, Body Composition, Athlete
University of Pavia
Observational
181
Pavia
2024-07-05
Active, closed
Amgen
Phase 3
89
Naples, Pisa
2024-07-05
Recruiting
Multi-biomarkers in DEE
NCT07909382Developmental and Epileptic Encephalopathies (DEE)
Istituto Giannina Gaslini
Observational
200
Bologna, Catanzaro, Florence, Genova, Milan, Roma
2024-07-04
Recruiting
Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Not applicable
120
Alessandria
2024-07-03
Recruiting
GlaxoSmithKline
Phase 1
675
Aviano PN, Milan, Naples, Roma
2024-07-02
Active, closed
Novartis Pharmaceuticals
Phase 2
155
Salerno
2024-07-02
Recruiting
AAVantgarde Bio Srl
Phase 1/2
15
Naples
2024-07-02
Recruiting
Bone Outcomes, Obesity, Sunlight, and Trauma in Children
NCT07143552Pediatric Fractures, Hypovitaminosis D, Obesity and Overweight
Paracelsus Medical University
Observational
100
Brixen, Meran
2024-07-01
Recruiting
Fluorescence Enhanced Stereotactic Surgery (FESS)
NCT07286903High Grade Glioma, High Grade Glioma (III or IV)
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Observational
20
Milan
2024-07-01
Recruiting
Biofeedback Based System to Enhance Robotic Assisted Gait Training in Children With Cerebral Palsy
NCT06947889Cerebral Palsy Infantile, Robotic Assisted Gait Training
G. d'Annunzio University
Observational
11
San Giovanni Rotondo
2024-07-01
Recruiting
European Foundation for Study of Chronic Liver Failure
Phase 2
90
Bologna, Turin
2024-07-01
Recruiting
Severe Complications During Ventricular Tachycardia or Premature Ventricular Complex Ablation
NCT07777744Ventricular Tachycardia (VT), Premature Ventricular Complexes
University Hospital, Basel, Switzerland
Observational
15,000
Torino
2024-07-01
Recruiting
Cyber-Human Systems for Personalized Well-being and Health
NCT06490783Geriatric Health Services, Health Services for the Elderly
Istituto per la Ricerca e l'Innovazione Biomedica
Observational
10
Messina
2024-07-01
Recruiting
Impact of Estimated Concentration of Propofol on Implicit Memory Formation
NCT06497855General Anaesthesia, Implicit Memory
University of Padova
Observational
80
Treviso
2024-07-01
Recruiting
Fondazione Oncotech
Observational
300
Avellino, Ancona, Aviano, Bari, Barletta, Bergamo, Caserta, Genova
2024-07-01
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
30
Rome
2024-06-30
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Not applicable
31
Arezzo, Bolzano, Catania, Pavia, Piacenza
2024-06-30
Recruiting
Fondazione IRCCS Policlinico San Matteo di Pavia
Observational
200
Pavia
2024-06-30
Active, closed
AstraZeneca
Phase 3
339
Brescia, Cona, Florence, Milan, Naples, Reggio Emilia, Roma, Rome
2024-06-29
Recruiting
argenx
Phase 2/3
12
Genova
2024-06-28
Active, closed
Novartis Pharmaceuticals
Phase 3
162
Milan, Perugia
2024-06-28
Recruiting
Master Framework For Relapse or Refractory Acute Myeloid Leukemia
NCT06459024Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS
Observational
4,000
Bologna, Brindisi, Brescia, Cuneo, Como, Cremona, Ferrara, Genova
2024-06-28
Recruiting
Boehringer Ingelheim
Phase 1/2
910
Ancona, Candiolo (TO), Meldola (FC), Milan, Misterbianco (CT), Naples, Rozzano
2024-06-28
Recruiting
IRCCS Sacro Cuore Don Calabria di Negrar
Not applicable
278
Bologna, Negrar, Florence
2024-06-28
Recruiting
Visual Involvement in Giant Cell Arteritis
NCT06500728Giant Cell Arteritis, Visual Impairment, Central Retinal Artery Occlusion, Anterior Ischemic Optic Neuropathy
ASST Fatebenefratelli Sacco
Observational
762
Milan
2024-06-27
Recruiting
Institution of an Italian Registry and Biobank for Biological Sample Collection
NCT06892964Lymphatic Malformation, Lymphatic Abnormality, Lymphangioma, Lymphatic Abnormalities
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
70
Roma
2024-06-27
Active, closed
AbbVie
Phase 3
1,400
Cona, Florence, Rozzano, Naples, Rome, Catania, Milan
2024-06-27
By invitation
Growing Up in Multifactorial Risk Conditions
NCT07477899Adverse Childhood Experiences, Developmental Risk, Psychomotor Development Disorders, Neurodevelopmental Disorders
IRCCS Eugenio Medea
Not applicable
352
Bosisio Parini
2024-06-26
Recruiting
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Observational
50
Milan
2024-06-26
Recruiting
A Registry-study of ELZONRIS in Participants With BPDCN
NCT07785154Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
DrugTagraxofusp
Stemline Therapeutics, Inc.
Observational
80
Alessandria, Bologna, Catania, Cuneo, Ferrara, Florence, Genova, Milan
2024-06-26
Active, closed
Genmab
Phase 3
621
Brescia, Cuneo, Milan, Naples, Roma, Rozzano
2024-06-25
Recruiting
Fondazione IRCCS Policlinico San Matteo di Pavia
Observational
400
Pavia
2024-06-25
Active, closed
UCB Biopharma SRL
Phase 3
176
Ancona, Località Torrette, Catania, Pisa, Roma
2024-06-25
Active, closed
Novo Nordisk A/S
Phase 3
10,000
Chieti, Caserta, Cona (Ferrara), Latina, Bergamo, San Donato Milanese, Turin, Pordenone
2024-06-25
Recruiting
A Study to Describe the Diagnostic and Therapeutic Path of Patients with NSCLC in Early Stage and Locally Advanced
NCT06467383Non-small Cell Lung Cancer, NSCLC, NSCLC, Stage III, NSCLC, Stage I
MSD Italia S.r.l.
Observational
600
San Giovanni Rotondo, Brescia, Campobasso, Catania, Florence, Genova, Messina, Milan
2024-06-25
Recruiting
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Phase 3
264
Bergamo, Bologna, Genova, Milan, Pavia, Rome, Treviso
2024-06-25
Recruiting
Merck Sharp & Dohme LLC
Phase 3
1,530
Naples, Misterbianco, Meldola (FC), Aviano, Rome, Brescia, Milan, Monza
2024-06-24
Recruiting
Effectiveness of Nurse Tele-consultation on the Quality of Elective Colonoscopy, Procedure-related Anxiety, and Financial Toxicity
NCT06887244Patient Satisfaction and Efficacy of Bowel-preparation, Colon Cancer Prevention
National Cancer Institute, Naples
Not applicable
534
Naples
2024-06-24
Recruiting
Società Italiana di Medicina Interna
Observational
2,326
San Fermo della Battaglia, Catanzaro, Florence, Bari, Bologna, Brescia, Milan, Modena
2024-06-24
Active, closed
Insulin Resistance and Coronary Microvascular Dysfunction in Patients With Myocardial Ischemia and Non-obstructive Coronary Artery Disease
NCT06597851Coronary Microvascular Dysfunction, Coronary Microvascular Disease, Insulin Resistance
Azienda Ospedaliera Universitaria Integrata Verona
Not applicable
40
Verona
2024-06-24
Recruiting
Cera™ Vascular Plug System Post-Market Clinical Follow-Up
NCT06099015Aneurysm, Endoleak, Pulmonary Arteriovenous Malformation, Portal Hypertension
Lifetech Scientific (Shenzhen) Co., Ltd.
Observational
132
Milan, Turin, Varese
2024-06-21
Recruiting
IRCCS San Raffaele
Observational
130
Milan
2024-06-20
Recruiting
Regina Elena Cancer Institute
Observational
40
Rome
2024-06-20
Recruiting
Istituto Nazionale di Ricovero e Cura per Anziani
Observational
374
Ancona, Cosenza
2024-06-20
Recruiting
Differentiating Heart Disease Between Adult-onset Autoimmune and Type 2 Diabetes
NCT07911007Diabete Mellitus, Autoimmune Diabetes, Latent Autoimmune Diabetes in Adult (LADA), Type 2 Diabetes
University of Roma La Sapienza
Not applicable
200
Rome
2024-06-20
Recruiting
Understanding the Subnormal Rescue ofNeurological Development in Congenital Hypothyroidism (2022E5SZEM)
NCT07893522Congenital Hypothyroidism, Neurodevelopmental Disorders
Istituto Giannina Gaslini
Observational
178
Genova, Milan, Naples
2024-06-20
Recruiting
AstraZeneca
Phase 3
240
Ancona, Bari, Catania, Milan, Padova, Palermo, Pavia, Pisa
2024-06-20
Recruiting
Merck Sharp & Dohme LLC
Phase 1/2
220
Milan, Roma
2024-06-20
Recruiting
Italian iTTP Registry
NCT06376786TTP - Thrombotic Thrombocytopenic Purpura
Fondazione Luigi Villa
Observational
132
Milan
2024-06-20
Active, closed
Ivy Brain Tumor Center
Phase 3
450
Bologna, Florence, Milan, Rozzano, Naples, Padova, Rome, Torino
2024-06-19
Active, closed
Celgene
Phase 3
850
Ravenna, Rome, Palermo, Novara
2024-06-19
Active, closed
H. Lundbeck A/S
Phase 2
16
Messina, Padua, Pisa, Rome, Turin
2024-06-19
By invitation
Sarepta Therapeutics, Inc.
Phase 1/2
60
Milan, Roma
2024-06-19
Recruiting
Fondazione Policlinico Universitario Campus Bio-Medico
Phase 4
26
Rome
2024-06-18
Active, closed
Unravelling the Role of Apoptosis in Platelets Biogenesis Through the Study of the Thrombocytopenia THC4
NCT07026578Thrombocytopenia, Isolated, Thrombocytopenia 4, CYCS MUTATION- ASSOCIATED THROMBOCYTOPENIA THC4
Fondazione IRCCS Policlinico San Matteo di Pavia
Observational
38
Pavia
2024-06-18
Active, closed
Fondazione IRCCS Policlinico San Matteo di Pavia
Observational
14
Pavia
2024-06-18
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
500
Bologna
2024-06-18
By invitation
Bicocca Epidemiological Assessment of Cardiovascular Risk Factors
NCT07207603Cardiovascular Risk Factors (e.g., Hypertension)
University of Milano Bicocca
Observational
1,000
Milan
2024-06-17
Active, closed
BioMarin Pharmaceutical
Phase 3
80
Genoa, Rome
2024-06-17
Recruiting
Evaluation of the PreCursor-M+® in CIN2
NCT06403618Cervical Intraepithelial Neoplasia Grade 2
European Institute of Oncology
Observational
100
Milan
2024-06-17
Recruiting
Boehringer Ingelheim
Phase 3
6,712
Bergamo, Foggia, Genova, Naples, Pavia, Roma, Rozzano
2024-06-17
Active, closed
Application of Linkage Analysis in the Identification of Novel Hereditary Factors in Familial Aneurysms
NCT06783803Familial Thoracic Aortic Aneurysm and Aortic Dissection
IRCCS Policlinico S. Donato
Observational
20
San Donato Milanese
2024-06-15
Recruiting
Azienda Ospedaliero Universitaria Maggiore della Carita
Observational
195
Novara
2024-06-15
Recruiting
Oncoinvent Solutions AS
Phase 2
114
Roma
2024-06-15
Not yet open
European Institute of Oncology
Not applicable
120
Milan
2024-06-15
Active, closed
AbbVie
Phase 3
184
L’Aquila, Rozzano, Rome, Milan
2024-06-14
Recruiting
Clinical Management and Outcomes of Primary Ovarian Leiomyosarcoma
NCT06749600Primary Ovarian Leiomyosarcoma
Azienda USL Reggio Emilia - IRCCS
Observational
30
Modena, Parma, Reggio Emilia, Avellino, Catania, Milan, Monza, Naples
2024-06-14
Recruiting
DEEP Substrate Mapping Versus Activation Mapping for VT
NCT06371729Ventricular Tachycardia
IRCCS Ospedale San Raffaele
Not applicable
222
Milan
2024-06-13
Recruiting
Università Vita-Salute San Raffaele
Not applicable
210
Milan
2024-06-13
Recruiting
ABX advanced biochemical compounds GmbH
Phase 3
434
Meldola, Verona
2024-06-13
Active, closed
Spine Surgery for Lenke 1 Adolescent Idiopathic Scoliosis
NCT06396286Scoliosis, Spine Deformity, Adolescent Idiopathic Scoliosis
Istituto Ortopedico Rizzoli
Not applicable
20
Bologna
2024-06-12
Recruiting
National Cancer Institute, Naples
Phase 3
500
Naples
2024-06-12
Recruiting
Istituto Ortopedico Rizzoli
Observational
35
Bologna
2024-06-12
Active, closed
Merck Sharp & Dohme LLC
Phase 3
550
Bari, Milan, Florence, Roma
2024-06-11
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
194
Rome
2024-06-10
Recruiting
Merck Sharp & Dohme LLC
Phase 3
851
Naples, Rome, Milan, Monza, Rozzano, Brescia, Genova, Novara
2024-06-10
Recruiting
LEO Pharma
Phase 3
195
Ancona, Brescia, Padova, Roma, Rome
2024-06-10
Recruiting
Robotically Assisted Surgery For Perihilar Cholangiocarcinoma: A Prospective Study
NCT06720883Cholangiocarcinoma Cancer, Perihilar Cholangiocarcinoma
Azienda Ospedaliera di Padova
Observational
32
Padova
2024-06-07
Active, closed
Janssen Research & Development, LLC
Phase 1
108
Ancona, Bergamo, Brescia, Meldola, Pisa, Rome
2024-06-07
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
5,000
Bologna
2024-06-07
Active, closed
Exelixis
Phase 2/3
600
Candiolo, Brescia, Catania, Milan, Naples, Rome, Rozzano, Verona
2024-06-07
Active, closed
GlaxoSmithKline
Phase 4
302
Brescia, Ferrara, Milan, Pisa, Reggio Emilia, Rome, Rozzano
2024-06-06
Recruiting
X4 Pharmaceuticals
Phase 3
176
Torrette, Brescia, Genova, Meldola, Monza, Roma, Torino
2024-06-06
Recruiting
Istituto Ortopedico Rizzoli
Observational
100
Bologna
2024-06-06
Recruiting
Markers of Favorable Response to Complement Inhibitors Therapy
NCT06455709Myasthenia Gravis, Generalized
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
50
Roma
2024-06-05
Recruiting
Merck Sharp & Dohme LLC
Phase 3
1,200
Bari, Monserrato, Rome, Milan, Rozzano, Naples, Turin, Pontedera
2024-06-05
Recruiting
Immunocore Ltd
Phase 3
680
Bari, Bergamo, Meldola, Milan, Modena, Naples, Padova, Perugia
2024-06-05
Active, closed
Amgen
Phase 3
563
Bari, Milan, Verona
2024-06-05
Recruiting
Spinocerebellar Ataxia Type 27B Natural History Study (SCA27B-NHS)
NCT06472557Spinocerebellar Ataxia Type 27B
University Hospital Tuebingen
Observational
300
Pisa
2024-06-04
Recruiting
Regina Elena Cancer Institute
Observational
256
Rome
2024-06-04
Recruiting
Kartos Therapeutics, Inc.
Phase 3
600
Alessandria, Ancona, Bologna, Brescia, Catania, Florence, Forlì, Milan
2024-06-03
Recruiting
Istituto Ortopedico Rizzoli
Not applicable
50
Bologna
2024-06-03
Active, closed
University of Bologna
Not applicable
101
Bologna
2024-06-03
Active, closed
Kumquat Biosciences Inc.
Phase 1
92
Rome, Naples
2024-06-03
Recruiting
Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Observational
60
Castellana Grotte
2024-06-01
Recruiting
Prevalence of Sarcopenic Obesity in COPD
NCT06822504Sarcopenic Obesity, COPD
IRCCS San Raffaele Roma
Observational
236
Roma
2024-06-01
Recruiting
Hedera Dx SA
Observational
1,000
Naples
2024-06-01
Active, closed
Windtree Therapeutics
Phase 1/2
20
Alessandria, Brescia, Milan, Turin
2024-06-01
Recruiting
Physical Exercise in Patients With Chronic Kidney Disease in Hemodialysis (Pehedal-ESKD)
NCT07820514Chronic Kidney Disease on Hemodialysis, Physical Exercise Behavior (Liking/Aversion)
Ricerca Nefrocenter
Not applicable
312
Torre del Greco
2024-06-01
Recruiting
University Hospital Padova
Not applicable
580
Padua
2024-06-01
Active, closed
ATRX/DAXX in EUS-FNB Specimens of Pan-NETs
NCT06406387Pancreatic Neuroendocrine Tumor
Azienda Ospedaliera Universitaria Integrata Verona
Observational
100
Verona
2024-06-01
Recruiting
Buzzi Children's Hospital
Observational
3,000
Milan
2024-06-01
Active, closed
University of Campania Luigi Vanvitelli
Observational
150
Naples
2024-06-01
Recruiting
Prospective Registry of EoSinophilic esOphagitis
NCT06443346Eosinophilic Esophagitis
IRCCS San Raffaele
Observational
1,000
Milan
2024-06-01
Recruiting
Istituto Auxologico Italiano
Observational
5,000
Acri, Ancona, Bari, Bergamo, Bologna, Cagliari, Catania, Corigliano-Rossano
2024-06-01
Recruiting
Risk of Falling and Cardiac Rehabilitation
NCT06908759Risk of Falling, Elderly (People Aged 65 or More), Cardiovascular Diseases
IRCCS San Raffaele Roma
Not applicable
150
Rome
2024-05-31
Active, closed
Janssen Research & Development, LLC
Phase 2
333
Bari, Ferrara, Florence, Milan, Novara, Padova, Palermo, Perugia
2024-05-30
Recruiting
Istituto Ortopedico Rizzoli
Observational
20
Bologna
2024-05-30
Recruiting
Costantino Errani
Observational
600
Bologna
2024-05-30
Active, closed
Stealth BioTherapeutics Inc.
Phase 3
313
Milan, Roma, Udine
2024-05-30
Recruiting
Kinematic Analysis of Manual Dexterity
NCT07875127Down Syndrome, Hemiparesis, Healthy Subjects
IRCCS San Raffaele Roma
Observational
60
Rome
2024-05-30
Active, closed
ELVN-002 With Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer
NCT06328738HER2-positive Breast Cancer, HER2-positive Gastric Cancer, HER2 Positive Solid Tumors, HER2 Amplification
DrugsELVN-002·Eribulin·Leucovorin·Trastuzumab
Enliven Therapeutics
Phase 1
275
Catanzaro, Milan, Monza, Pisa, Reggio Emilia, Rome
2024-05-30
Active, closed
Amgen
Phase 1/2
94
Milan, Pisa, Varese
2024-05-30
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Not applicable
50
Bologna
2024-05-29
Active, closed
Cytokinetics
Phase 2/3
65
Florence
2024-05-29
Active, closed
Amgen
Phase 1
120
Milan, Rozzano MI, Verona
2024-05-29
Active, closed
A Study of JNJ-88998377 for Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
NCT06470438Lymphoma, Non-Hodgkin, Refractory B-Cell NHL, Relapsed B-cell NHL
Janssen Research & Development, LLC
Phase 1
58
Bologna
2024-05-28
Recruiting
PENTA Foundation
Not applicable
3,080
Ferrara, Modena, Palermo, Vicenza
2024-05-28
Recruiting
Istituto Auxologico Italiano
Observational
90
Oggebbio
2024-05-28
Recruiting
Harmony Biosciences Management, Inc.
Phase 3
134
Florence, Genova, Milan, Padova, Roma, Trieste
2024-05-28
Active, closed
Clinical Significance of Liquid Biopsy in Brain Tumor Patients: a 5-ALA Guided Approach
NCT07420543Brain Tumors and/or Solid Tumors Including, Glioblastoma, Glioblastoma (GBM), Glioblastoma - Category
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Observational
30
Milan
2024-05-27
Recruiting
Regina Elena Cancer Institute
Observational
10
Rome
2024-05-25
Recruiting
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
NCT06419374Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
DrugPegozafermin
Hoffmann-La Roche
Phase 3
1,800
Bergamo, Foggia, Milan, Novara, Palermo, Roma, Rome, Rozzano
2024-05-24
Recruiting
Fondazione IRCCS Policlinico San Matteo di Pavia
Not applicable
150
Pavia
2024-05-24
Recruiting
CDR-Life AG
Phase 1
42
Milan
2024-05-24
Recruiting
Merck Sharp & Dohme LLC
Phase 3
348
Naples, Ravenna, Aviano, Rome, Milan, Livorno, Padova
2024-05-24
Recruiting
University Hospital, Antwerp
Phase 3
174
Milan, Arezzo, Bergamo, Brescia, Florence, Lecco, Pavia, Pisa
2024-05-24
Recruiting
Société des Produits Nestlé (SPN)
Not applicable
380
Cefalù, Genova, Palermo, Roma, Tricase
2024-05-24
Recruiting
Elisa Giannetta
Observational
150
Rome
2024-05-24
Recruiting
Expanding NGS Data with Optical Genome Mapping (OGM)
NCT06851377Neurodevelopmental Disorder (Diagnosis)
IRCCS Eugenio Medea
Not applicable
60
Bosisio Parini
2024-05-23
Recruiting
Fondazione Italiana Linfomi - ETS
Phase 2
28
Alessandria, Aviano, Bologna, Brescia, Milan, Naples, Novara, Palermo
2024-05-23
Recruiting
Centro di Riferimento Oncologico - Aviano
Observational
180
Aviano
2024-05-23
Recruiting
Fondazione IRCCS Policlinico San Matteo di Pavia
Observational
400
Pavia
2024-05-23
Recruiting
Comparison of Three Pre-oxygenation Strategies
NCT06370689Emergencies, Anesthesia
Institute of Mountain Emergency Medicine
Not applicable
45
Bolzano
2024-05-23
Recruiting
A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)
NCT06351631Thrombocythemia, Essential, Primary Myelofibrosis, Myelofibrosis, Post-polycythemia Vera Myelofibrosis
DrugBomedemstat
Merck Sharp & Dohme LLC
Phase 3
400
Florence, Alessandria, Bologna, Varese
2024-05-23
Active, closed
Azienda Ospedaliero-Universitaria di Parma
Observational
110
Parma
2024-05-23
Recruiting
Prognostic Recovery Observations and Guidance for Evaluating Stroke Survivors
NCT06465758Acute Stroke, Functional Recovery, Prognostic Factors
IRCCS San Raffaele
Observational
360
Milan
2024-05-21
Recruiting
IRCCS Eugenio Medea
Not applicable
300
Bosisio Parini
2024-05-21
Recruiting
Novartis Pharmaceuticals
Phase 3
550
Cona, Padova, Pisa, Roma, Torino
2024-05-21
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
1,100
Bologna
2024-05-21
Recruiting
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Observational
180
Bologna
2024-05-21
Recruiting
Cp eArly REhabilitation
NCT06737471Cerebral Palsy
IRCCS Eugenio Medea
Observational
96
Como, Bosisio Parini, Sesto San Giovanni, Carate Brianza, Vedano Olona
2024-05-21
Active, closed
International Extranodal Lymphoma Study Group (IELSG)
Phase 3
122
Bari, Bologna, Brescia, Catania, Meldola, Milan, Novara, Palermo
2024-05-21
Recruiting
Daiichi Sankyo
Phase 3
540
Bari, Bergamo, Brescia, Catania, Catanzaro, Genova, Milan, Monza
2024-05-21
Recruiting
Improving the Diagnostic Accuracy of Children with DoC (IDeAl DesiRE)
NCT06635291Acquired Brain Injury, Disorder of Consciousness
IRCCS Eugenio Medea
Observational
113
Bosisio Parini
2024-05-20
Recruiting
A Study of Sofe-M in Participants With Selected Advanced Solid Tumors
NCT06400472Ovarian Neoplasms, Endometrial Neoplasms, Uterine Cervical Neoplasms, Carcinoma, Non-Small-Cell Lung
DrugsSofe-M·Itraconazole·Bevacizumab·Carboplatin
Eli Lilly and Company
Phase 1
575
Milan
2024-05-20
Active, closed
Merck Sharp & Dohme LLC
Phase 1/2
220
Rome, Milan, Rozzano, Verona
2024-05-20
Recruiting
Laterza Lucrezia
Observational
20
Roma
2024-05-20
Recruiting
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
NCT06237452Clostridium Difficile, Clostridium Difficile Infections, Clostridium Difficile Infection Recurrence, Clostridioides Difficile Infection
Vedanta Biosciences, Inc.
Phase 3
852
Alessandria, Lecco, Milan, Monza, Naples, Pavia, Modena, Roma
2024-05-20
Active, closed
A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors
NCT06157892Breast Neoplasms, Gastroesophageal Junction Adenocarcinoma, HER2 Low Breast Neoplasms, HER2 Positive Breast Neoplasms
DrugsTucatinib·Disitamab Vedotin
Seagen, a wholly owned subsidiary of Pfizer
Phase 2
54
Naples, Milan, Misterbianco (CT), Verona
2024-05-20
Recruiting
IRCCS San Raffaele Roma
Not applicable
70
Cassino, Rome, Sulmona
2024-05-19
Active, closed
AbbVie
Phase 3
421
Legnano, Turin, Rome, Ancona, Catania
2024-05-19
Active, closed
Università Vita-Salute San Raffaele
Not applicable
400
Cagliari, Milan
2024-05-16
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
250
Rome
2024-05-16
Recruiting
NMD Pharma A/S
Phase 2
84
Bergamo, Bologna, Genova, Milan, Naples, Pisa, Roma
2024-05-16
Recruiting
Hearing and Structure Preservation Via ECochG
NCT06268340Hearing Loss, Sensorineural, Severe-to-profound Hearing Loss
Advanced Bionics AG
Not applicable
102
Torino
2024-05-15
Recruiting
Abbott Medical Devices
Observational
50
San Donato Milanese
2024-05-15
Recruiting
Boehringer Ingelheim
Phase 2
175
Florence, Milan, Naples, Roma, Rozzano, Torrette Di Ancona
2024-05-15
By invitation
University of Pavia
Not applicable
20
Pavia
2024-05-15
Active, closed
Novartis Pharmaceuticals
Phase 1
42
Reggio Emilia
2024-05-15
Recruiting
Jvan Casarin, MD PhD
Observational
1,500
Varese
2024-05-15
Active, closed
IRCCS Eugenio Medea
Observational
25
Bosisio Parini
2024-05-15
Active, closed
The OPBC-07/microNAC Study
NCT06529302Breast Cancer
University Hospital, Basel, Switzerland
Observational
2,000
Milan, Naples, Padova, Pavia, Roma
2024-05-15
Recruiting
Angelina Passaro
Observational
150
Ferrara, Poggio Renatico
2024-05-14
Recruiting
Corheart 6 LVAS Study
NCT05876000Refractory Heart Failure
Shenzhen Core Medical Technology CO.,LTD.
Not applicable
53
Milan, Torino
2024-05-14
Recruiting
Ordastobart (INBRX-106) Add-on to Pembrolizumab in 1L HPV+ PD-L1+ R/M OPSCC (HexAgon-HN)
NCT06295731Head and Neck Squamous Cell Carcinoma (HNSCC), HPV Oropharyngeal Squamous Cell Carcinoma (HPV+ OPSCC)
DrugsKeytruda·Pembrolizumab
Inhibrx Biosciences, Inc
Phase 2/3
450
Naples, Milan, Pavia
2024-05-14
Active, closed
European Myeloma Network B.V.
Phase 2
50
Bari, Bergamo, Florence, Genova, Meldola, Novara, Padova, Pavia
2024-05-14
Recruiting
The Cardiovascular Prevention Program
NCT06362538Cardiovascular Prevention
DrugBlood sampling
Maria Cecilia Hospital
Not applicable
150
Cotignola
2024-05-13
Recruiting
Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna
Not applicable
250
Bagno a Ripoli, Florence, Massa, Milan
2024-05-13
Active, closed
Familial Adenomatous Poliposys Italian Network (Rete Italiana Poliposi Adenomatosa Familiare)
NCT07461246Familial Adenomatous Polyposis (FAP), Attenuated Familial Adenomatous Polyposis (AFAP), MUTYH-Associated Polyposis (MAP), Non-APC/MUTYH Associated Polyposis (NAMP)
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Observational
1,500
Milan
2024-05-13
Active, closed
Biohaven Therapeutics Ltd.
Phase 2/3
390
Chieti, Catanzaro, Naples, Bologna, Rome, Genoa, Milan, Pavia
2024-05-13
Recruiting
Istituto Ortopedico Rizzoli
Not applicable
136
Bologna
2024-05-13
Recruiting
Centro di Riferimento Oncologico - Aviano
Observational
1,000
Aviano, Caserta, Naples, Trieste
2024-05-13
Recruiting
Hopital Foch
Phase 2
640
Milan, Livorno
2024-05-10
Recruiting
Lorenza Driul
Observational
200
Udine
2024-05-09
Active, closed
Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine Patients
NCT06414044Migraine, Migraine With Aura, Migraine Without Aura, Chronic Migraine
DrugAtogepant
University of Florence
Observational
500
Florence, Roma
2024-05-09
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
496
Milan
2024-05-09
Recruiting
BNP in Pediatric Metabolic Syndrome
NCT07181733Metabolic Syndrome
Fondazione IRCCS Policlinico San Matteo di Pavia
Observational
70
Pavia
2024-05-08
Active, closed
Sanofi
Phase 3
1,541
Milan, Rozzano, Rome, Bologna, Catania, L’Aquila, Pisa, Vicenza
2024-05-08
Recruiting
Centro Cardiologico Monzino
Observational
1,400
Milan
2024-05-07
Recruiting
W.L.Gore & Associates
Observational
2,000
Ancona, Bari, Pavia, Torino, Verona
2024-05-07
Active, closed
Fondazione Italiana Linfomi - ETS
Observational
56
Avellino, Alessandria, Biella, Milan, Novara, Pavia, Piacenza, Torino
2024-05-07
Recruiting
Solid Biosciences Inc.
Phase 1/2
60
Rome
2024-05-06
Recruiting
PSC Partners Seeking a Cure
Observational
2,000
Milan
2024-05-06
Recruiting
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Observational
266
Milan
2024-05-06
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
148
Roma
2024-05-06
Active, closed
Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Observational
20
Alessandria
2024-05-06
Recruiting
University of Bari Aldo Moro
Not applicable
76
Bari
2024-05-06
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
129
Rome
2024-05-06
Recruiting
University of Rome G. Marconi
Not applicable
114
Bologna, Rome
2024-05-06
Recruiting
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
NCT07066137Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
150
Messina
2024-05-05
Active, closed
Merck Sharp & Dohme LLC
Phase 3
473
Naples, Rome, Milan, Pisa
2024-05-03
Recruiting
Istituto Nazionale di Ricovero e Cura per Anziani
Not applicable
12
Ancona, Fermo
2024-05-03
Recruiting
Molecular-Based Selection of Patients with Head and Neck Squamous Cell Carcinoma: Biomarker Analysis
NCT06905145Head and Neck Squamous Cell Carcinoma, Locally Advanced Stage
National Cancer Institute, Naples
Observational
128
Naples
2024-05-03
By invitation
Federico II University
Not applicable
20
Naples
2024-05-03
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Observational
207
Roma
2024-05-02
Active, closed
Hoffmann-La Roche
Phase 2
256
Tricase (LE), Rome, Milan, Pavia
2024-05-02
Active, closed
Profiling Vulnerability and Resilience for Mental Illness Following Viral Infections
NCT06945627Severe Mental Illness, Inflammation, Viral Infections, Mood Disorders
Sara Poletti
Observational
408,551
Milan
2024-05-02
Recruiting
Cardiac Implantable Electronic Device- Induced Remodelling of Tricuspid Valve and Right Chambers
NCT06914570Cardiac Pacing, Artificial, Tricuspid Valve Regurgitation, Non-rheumatic
Istituto Auxologico Italiano
Observational
350
Milan
2024-05-01
Active, closed
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
1,000
Milan
2024-05-01
Recruiting
University of Milan
Phase 2/3
34
Milan
2024-05-01
Recruiting
Can Gluten/Wheat or Other Foods be Responsible for FMF Attacks
NCT06338891Familial Mediterranean Fever, Non-celiac Gluten Sensitivity
University of Palermo
Observational
60
Palermo
2024-05-01
Active, closed
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Not applicable
1,600
Rome
2024-05-01
By invitation
University of Modena and Reggio Emilia
Observational
500
San Miniato, Modena
2024-05-01
Active, closed
Azienda Ospedaliero, Universitaria Pisana
Observational
1,000
Bari, Catania, Pisa
2024-05-01
Not yet open
TRAnscutaneous vaGUS Nerve Stimulation in Patients With Chronic Heart Failure
NCT06355388Heart Failure, Heart Failure With Reduced Ejection Fraction, Heart Failure With Midrange Ejection Fraction
Fondazione Toscana Gabriele Monasterio
Not applicable
24
Pisa
2024-05-01
Recruiting
Italian Registry of Allergen ImmunoTherapy
NCT06499480Allergic Respiratory Disease
Società Italiana di Allergologia, Asma e Immunologia Clinica
Observational
5,000
Rozzano, Florence
2024-05-01
Recruiting
Enhanced Valves Interventions and Safe AI Generated End Results
NCT07213531Heart Valve Disease, TAVI, M-TEER, TTVI
Montreal Heart Institute
Observational
21,000
Brescia, Milan
2024-05-01
Active, closed
Eli Lilly and Company
Phase 3
10,000
Bologna, Ferrara, Genova, Milan, Palermo, Perugia, Pisa, Roma
2024-04-30
By invitation
Visuospatial and Affective Abilities in Parkinson Disease
NCT06341829Parkinson Disease, Alexithymia, Visuospatial/Perceptual Abilities
IRCCS Centro Neurolesi Bonino Pulejo
Not applicable
126
Messina
2024-04-30
By invitation
Travere Therapeutics, Inc.
Phase 3
100
Bari, Genova, Milan, Monza, Padova
2024-04-30
Recruiting
Fondazione del Piemonte per l'Oncologia
Not applicable
200
Candiolo
2024-04-30
Recruiting
Francesco De Cobelli
Phase 2
33
Bergamo, Milan, Naples, Pisa
2024-04-30
Active, closed
Fondazione IRCCS Policlinico San Matteo di Pavia
Not applicable
534
Pavia
2024-04-29
Active, closed
Erasca, Inc.
Phase 3
78
Milan, Roma, Udine
2024-04-29
Recruiting
Eli Lilly and Company
Phase 3
510
Florence, Milan, Naples, Padova, Pisa, Rome, Vimercate
2024-04-29
Recruiting
AstraZeneca
Phase 3
582
Milan, Monza, Orbassano, Padova, Parma
2024-04-29
Active, closed
Servier Bio-Innovation LLC
Phase 1/2
61
Milan, Rozzano, Verona
2024-04-29
Recruiting
Costantino Errani
Observational
150
Bologna
2024-04-29
Recruiting
Bambino Gesù Hospital and Research Institute
Phase 1
24
Rome
2024-04-28
Recruiting
CSL Behring
Phase 2/3
3,110
Bologna, Brescia, Cagliari, Caserta, Catania, Ferrara, Florence, Foggia
2024-04-27
Active, closed
Istituto Scientifico Italiano Colonna Vertebrale
Observational
9,651
Milan
2024-04-24
Active, closed
Heart Failure Patient Management and Interventions Using Continuous Patient Monitoring Outside Hospitals and Real-world Data
NCT07008729Chronic Heart Failure, Heart Transplant Recipient, Left Ventricular Assist Device
Puerta de Hierro University Hospital
Not applicable
390
Bologna
2024-04-24
By invitation
ACADIA Pharmaceuticals Inc.
Phase 3
752
Brescia, Salerno, Tricase
2024-04-23
Recruiting
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Observational
40
Milan
2024-04-23
By invitation
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Not applicable
52
Milan
2024-04-23
Recruiting
University of Udine
Observational
90
Udine
2024-04-22
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Priya Life Science (2026). Clinical trial register: studies with an Italian investigative site. Derived from ClinicalTrials.gov. Retrieved 12 November 2026. https://priyalifescience.com/clinical-trials-italy?page=7

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Italy and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 6,779 studies in total at the last sync on 10 Nov 2026, 03:19 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in Italy?

4,070 of the 6,779 studies in this register are recruiting new participants as of the 10 Nov 2026, 03:19 UTC sync. A further 574 have not yet opened recruitment, 1,938 are active but closed to new participants, and 197 are enrolling by invitation only. Eligibility for any study is decided by its study team.

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Browse trials by condition

Breast Cancer (158) Heart Failure (65) Parkinson Disease (62) Multiple Myeloma (61) Prostate Cancer (57) Multiple Sclerosis (56) Stroke (55) Obesity (54) Ovarian Cancer (53) Coronary Artery Disease (43) Colorectal Cancer (42) Ulcerative Colitis (38) Non-small Cell Lung Cancer (38) Endometrial Cancer (37) Non-Small Cell Lung Cancer (37)
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Browse trials by site location

Milan (2847) Bologna (1281) Roma (1263) Naples (980) Rome (966) Florence (788) Pavia (571) Brescia (523) Padova (503) Genova (491) Rozzano (472) Bari (451) Pisa (399) Bergamo (378) Meldola (355)
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.