Clinical trial register · India

Clinical Trials in New Delhi, 2026

Every study on the ClinicalTrials.gov registry that lists a site in India and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 1120 matching records held by the registry are in this view. Synced 07 Nov 2026, 03:16 UTC

1120

Studies in scope

all four open statuses

608

Recruiting now

open to new participants

218

Lead sponsors

across recruiting studies

Top sites

New Delhi 339 Mumbai 260 Hyderabad 233 Bangalore 199 Pune 186

Trials with a site in New Delhi

Status

Study

Lead sponsor

Phase

Enrol

Indian sites

Start

Not yet open

National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Evaluating Mesenchymal Stem-Cell (MSC) Therapy in Non-viral Acute on Chronic Liver Failure (ACLF) Patients - Phase-III Trial

NCT07075315Acute-On-Chronic Liver Failure

Institute of Liver and Biliary Sciences, India

Phase 3

100

Chandigarh, New Delhi

2028-01

Not yet open

Patients Gender Influence on Communication of Anaesthesia Risk

NCT06814236Anaesthesia Complication

Sir Ganga Ram Hospital

Observational

100

New Delhi

2027-12

Not yet open

COOLing of the Ischemic PENumbra in Patients With Acute Ischemic Stroke.

NCT07844096Acute Ischemic Stroke

Christian Medical College and Hospital, Ludhiana, India

Not applicable

Kochi, New Delhi, Ludhiana, Vellore, Kharagpur

2027-09-01

Not yet open

National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Evaluating Mesenchymal Stem Cell Therapy in Non-viral Acute on Chronic Liver Failure (ACLF) Patient- Phase-II Trial

NCT07131306Acute-On-Chronic Liver Failure

Institute of Liver and Biliary Sciences, India

Phase 2

100

New Delhi

2027-01

Not yet open

Long-term Extension Study to Evaluate Safety and Tolerability of Admilparant in Participants With Pulmonary Fibrosis

NCT07441408Pulmonary Fibrosis

DrugAdmilparant

Bristol-Myers Squibb

Phase 3

2,380

Belagavi, Nagpur, Pune, New Delhi, Dehradun, Kolkata, Ahemdabad, Bangalore

2026-12-16

Not yet open

A Study to Assess the Safety, and Tolerability of Nivolumab + Relatlimab Fixed-Dose Combination (FDC) In Unresectable or Metastatic Melanoma Participants In India

NCT07459543Unresectable Melanoma, Metastatic Melanoma

DrugsRelatlimab·Nivolumab

Bristol-Myers Squibb

Phase 4

Nashik, Mumbai, Navi Mumbai, Pune, Bhubaneswar, Chennai, Nagpur, New Delhi

2026-11-15

Not yet open

Metformin in Acute Ischemic Stroke

NCT07899307Acute Ischemic Stroke

DrugMetfomin

All India Institute of Medical Sciences

Phase 3

440

Chandigarh, New Delhi, Puducherry, Varanasi

2026-11-01

Not yet open

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease

NCT07838155Alzheimer Disease

DrugDonanemab

Eli Lilly and Company

Phase 4

Bangalore, Hyderabad, Kolkata, Mumbai, New Delhi, Tamil Nadu, Vellore

2026-11

Not yet open

Cost-Effectiveness of Upfront Supplemental Anaesthesia in Symptomatic Irreversible Pulpitis

NCT07907120Irreversible Pulpitis, Anesthesia, Local

Jamia Millia Islamia

Phase 4

234

New Delhi

2026-10-30

Not yet open

Cefepime-Zidebactam Versus Ceftazidime-Avibactam With or Without Colistin for Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia

NCT07885891Hospital Acquired Bacterial Pneumonia (HABP), Ventilator Associated Bacterial Pneumonia (VABP)

DrugsWithout Colistin·Ceftazidime-avibactam

Wockhardt

Phase 3

324

Gurgaon, Mumbai, Pune, New Delhi, Pimpri-Chinchwad, Jaipur, Chengalpattu, Secunderabad

2026-10-28

Recruiting

A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A

NCT07830732Haemophilia A

Novo Nordisk A/S

Phase 3

Guwahati, Kozhikode, New Delhi, Bhubaneswar, Hyderabad, Bangalore

2026-10-16

Recruiting

A Clinical Study of Enlicitide (MK-0616) in Adults With Hyperlipidemia in India (MK-0616-038)

NCT07821944Hyperlipidemia, Hypercholesterolemia

DrugsEnlicitide Decanoate·Enlicitide

Merck Sharp & Dohme LLC

Phase 3

150

Belagavi, New Delhi

2026-10-15

Not yet open

A Study of Selpercatinib (LY3527723) in Participants With Rearranged During Transfection (RET)-Altered Cancers in India

NCT07822880Thyroid Neoplasms, Carcinoma, Non-Small-Cell Lung

DrugSelpercatinib

Eli Lilly and Company

Phase 4

Ahmedabad, Bengaluru, Bhubaneswar, Hisar, Kolkata, Kozhikode, Mumbai (E), New Delhi

2026-10

Not yet open

Evaluation of Functional Dimensions of Macintosh Laryngoscope Blade During Direct Laryngoscopy in Patients With Normal Mouth Opening

NCT02639897Submucous Fibrosis

Sir Ganga Ram Hospital

Observational

100

New Delhi

2026-10

Not yet open

Study to Evaluate the Efficacy and Safety of Nizubaglustat (AZ-3102) in Patients With Gaucher Disease Type 3 (GD3)

NCT07715084Gaucher Disease Type 3

DrugNizubaglustat

Azafaros B.V.

Phase 2

Jaipur, New Delhi

2026-09-28

Not yet open

Incidence of Post TIPS/DIPS Heart Failure and the Factors Associated With Post-TIPS/DIPS Heart Failure.

NCT07880639Liver Diseases

Institute of Liver and Biliary Sciences, India

Observational

127

New Delhi

2026-09-27

Recruiting

Torvutatug Samrotecan With or Without Bevacizumab as Maintenance Treatment of Platinum-sensitive Relapsed Epithelial Ovarian Cancer

NCT07816666Platinum-sensitive Relapsed Epithelial Ovarian Cancer, Platinum-sensitive Relapsed Fallopian Tube Cancer, Platinum-sensitive Relapsed Primary Peritoneal Cancer

DrugsTorvutatug samrotecan·Bevacizumab

AstraZeneca

Phase 3

600

Ahmedabad, Bangalore, Gūrgaon, Kottayam, Madurai, Nashik, New Delhi, Vadodara

2026-09-24

Recruiting

Torvutatug Samrotecan Plus Bevacizumab as First-line Maintenance in Non-Homologous Recombination Deficiency (Non-HRD) Positive Advanced Epithelial Ovarian Cancer

NCT07851025Epithelial Ovarian Cancer

DrugsTorvutatug samrotecan·Avastin·Bevacizumab

AstraZeneca

Phase 3

950

Ansārinagar, Bhubaneswar, Hyderabad, Mumbai, Nagpur, Nashik, New Delhi, Pune

2026-09-16

Recruiting

Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05)

NCT07711002Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)

DrugsSaruparib·Abiraterone·Darolutamide·Enzalutamide

AstraZeneca

Phase 3

1,330

Ansārinagar, Bangalore, Delhi, Kannur, Nagpur, New Delhi, Vadodara

2026-09-15

Recruiting

A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

NCT07623161Myelofibrosis, Anemia

DrugElritercept

Takeda

Phase 3

324

Gurgaon, Kochi, Thiruvananthapuram, Pune, New Delhi, Rohini, Chennai, Hyderabad

2026-09-10

Not yet open

Effect of CSIR-Developed High-Protein, Low-Glycaemic Index Rice on Glycaemic Response in Individuals With Prediabetes

NCT07762768Prediabetes

Diabetes Foundation, India

Not applicable

New Delhi

2026-09-01

Not yet open

Efficacy of Low Glycemic Index Diet vs Modified Atkins Diet and Gluten Free Casein Free Diet as add-on Therapy With Standard of Care in Children With Autism Spectrum Disorder

NCT07797725Autism Spectrum Disorder

All India Institute of Medical Sciences

Not applicable

123

New Delhi

2026-09-01

Not yet open

Admission, Triage, and Discharge Criteria for Oncological Patients in the Intensive Care Unit

NCT07809490Cancer, Critical Care, Cancer Critically Ill

Onco Critical Care Society

Observational

New Delhi

2026-08-31

Recruiting

Rollover Study for Participants Who Have Completed a Previous Clinical Study With Anifrolumab (Saphnelo) and Clinically Benefited From Continued Treatment

NCT07691970Systemic Sclerosis Cutaneous Lupus E Myopathies Systemic Lupus Erythematosus

DrugAnifrolumab

AstraZeneca

Phase 3

1,072

Hyderabad, Kolkata, New Delhi, Pune

2026-08-31

Recruiting

To Develop and Validate an Equation for Determination of Major Adverse Kidney Events in Patients With Decompensated Cirrhosis and Ascites.

NCT07794787Decompensated Cirrhosis

Institute of Liver and Biliary Sciences, India

Observational

400

New Delhi

2026-08-31

Recruiting

A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

NCT07759245Pulmonary Disease, Chronic Obstructive

DrugBrenipatide

Eli Lilly and Company

Phase 2

606

Ahmedabad, Allahabād, Bangalore, Bhopal, Chhatrapati Sambhajinagar, Lucknow, Nagpur, New Delhi

2026-08-07

Recruiting

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes

NCT07282613Diabetes Mellitus, Type 2

DrugCagriSema

Novo Nordisk A/S

Phase 3

Guntur, Surat, Bangalore, New Delhi, Delhi, Kanpur, Kolkata, Kolhāpur

2026-08-04

Not yet open

EFFECT OF ANODAL TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS) OF PRIMARY MOTOR CORTEX ON HEADACHE FREQUENCY IN PATIENTS WITH CHRONIC MIGRAINE

NCT07743814Chronic Migraine Headache, Chronic Migraine, Headache

Dr. Ram Manohar Lohia Hospital

Phase 3

New Delhi

2026-08-01

Recruiting

A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

NCT07497087Systemic Sclerosis

Boehringer Ingelheim

Phase 3

448

Bangalore, Bhubaneswar, Gurugram, Hyderabad, Kochi, Maharashtra, New Delhi

2026-07-27

Recruiting

An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC

NCT07720284High-risk Muscle Invasive Urothelial Carcinoma

DrugsRilvegostomig·Enfortumab Vedotin·Dato-DXd·Opdivo

AstraZeneca

Phase 3

915

Kolkata, Kottayam, Nashik, Navi Mumbai, New Delhi

2026-07-16

Recruiting

A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes

NCT07668336Diabetes Mellitus, Type 2

DrugsDulaglutide·Orforglipron

Eli Lilly and Company

Phase 3

170

Ahmedabad, Aligarh, Bhubaneswar, Guntur, Mumbai, Nashik, New Delhi

2026-07-08

Recruiting

Influence of Donor and Recipient Genetic Polymorphisms on Graft Steatosis After Liver Transplant

NCT07685353Chronic Liver Disease and Cirrhosis

Institute of Liver and Biliary Sciences, India

Observational

New Delhi

2026-07-07

Recruiting

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

NCT07476287Small Cell Lung Cancer, Small Cell Lung Cancer ( SCLC ), Transformed Small Cell Lung Cancer, Lung Neoplasms

DrugPF-08634404

Pfizer

Phase 2

Kottayam, New Delhi

2026-07-02

Not yet open

AIRCARE (Air Pollution and Cancer Research Ecosystem): Center for Advanced Research on Environmental Health and Lung Cancer Risk

NCT07553598Lung Cancer

All India Institute of Medical Sciences

Observational

3,230

New Delhi

2026-07

Recruiting

Correlation of Neck Dimensions of Airway Evaluation

NCT07668297Airway Assessment, Laryngoscopy

Sir Ganga Ram Hospital

Observational

240

New Delhi

2026-06-25

Recruiting

A Phase 3 Study in India to Describe the Safety and Immunogenicity of RSVpreF

NCT07653100Respiratory Syncytial Virus (RSV)

DrugRSVpreF

Pfizer

Phase 3

540

Visakhapatnam, Bangalore, Belagavi, Nashik, Pune, Dwarka, New Delhi, Jaipur

2026-06-22

Not yet open

Effect of Ursodeoxycholic Acid Supplementation on Liver Regeneration in Adult Living Donor Liver Transplant (LDLT) Recipients.

NCT07664020Chronic Liver Disease

DrugUrsodeoxycholic Acid

Institute of Liver and Biliary Sciences, India

Not applicable

130

New Delhi

2026-06-18

Recruiting

A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

NCT07518186Multiple Myeloma

DrugsRamantamig·Teclistamab

Janssen Research & Development, LLC

Phase 3

700

Bengaluru, Gūrgaon, Jaipur, Kolkata, New Delhi, Pune

2026-05-31

Recruiting

A Study of TAK-755 in Adults With Acute Ischemic Stroke

NCT07392450Acute Ischemic Stroke

DrugTAK-755

Takeda

Phase 2

222

Belagavi, Kochi, Ludhiana, Kolkata, New Delhi

2026-05-17

Recruiting

AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

NCT07571109Obesity, Overweight, Obstructive Sleep Apnoea

DrugNNC0487-0111

Novo Nordisk A/S

Phase 3

300

Guntur, Vijayawada, Bengaluru, Kochi, Mumbai, Nagpur, New Delhi, Delhi

2026-05-05

Recruiting

A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)

NCT07409181Systemic Lupus Erythematosus

DrugBI 3000202

Boehringer Ingelheim

Phase 2

405

Kochi, Kolkata, Maharashtra, New Delhi

2026-04-20

Not yet open

Safety and Efficacy of Finerenone in Metabolic Dysfunction Associated Steatotic Liver Disease(MASLD/NAFLD) Related Cirrhosis Patients With Ascites in Prevention of Chronic Kidney Disease.

NCT07585526MASLD, Chronic Kidney Diseases

DrugsSpironolactone·Finerenone

Institute of Liver and Biliary Sciences, India

Not applicable

160

New Delhi

2026-04-15

Not yet open

Comparison of Topical Photodynamic Therapy With Topical Calcipotriol in Management of Oral Leukoplakia

NCT07453472Oral Leukoplakia

Dr. Shalini Gupta

Phase 3

166

New Delhi

2026-04

Not yet open

EFFECT OF ANODAL TRANSCRANIAL DIRECT CURRENT STIMULATION ON NAMING IN APHASIC PATIENTS WITH ACUTE ISCHEMIC STROKE

NCT07496645Acute Ischemic Cerebrovascular Disease, Post Stroke Aphasia, Aphasia Following Cerebral Infarction, Aphasia, Acquired

Dr. Ram Manohar Lohia Hospital

Phase 3

New Delhi

2026-03-31

Recruiting

Assessment of Changes in Bone Mineral Metabolism After Liver Transplantation by Bone Mineral Densitometry

NCT07480057Chronic Liver Disease and ACLF

Institute of Liver and Biliary Sciences, India

Observational

100

New Delhi

2026-03-18

Recruiting

To Revisit the Yield of Staging Laparoscopy in Hepatopancreatobiliary Malignancies

NCT07480005HPB Malignancies

Institute of Liver and Biliary Sciences, India

Observational

350

New Delhi

2026-03-18

Recruiting

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

NCT07361497Non-small Cell Lung Cancer (NSCLC)

DrugsPumitamig·Durvalumab

Bristol-Myers Squibb

Phase 3

850

Eluru, Goraj, Pūlakkōd, Chhatrapati Sambhajinagar, Mumbai, Nagpur, Dwarka, New Delhi

2026-03-16

Not yet open

Carvedilol and Midodrine Versus Carvedilol Alone in Preventing Early Rebleed in Patients With Cirrhosis.

NCT07465471Liver Cirrhosis

DrugCarvedilol

Institute of Liver and Biliary Sciences, India

Not applicable

210

New Delhi

2026-03-01

Not yet open

Serosurvey of HAV Immunity and Single-dose Vaccine Immunogenicity Among Patients With Cirrhosis

NCT07433881Liver Cirrhosis

Institute of Liver and Biliary Sciences, India

Observational

360

New Delhi

2026-02-25

Recruiting

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

NCT07363694Moderate to Severe Chronic Obstructive Pulmonary Disease

Pfizer

Phase 2/3

1,156

Belagavi, Thane, New Delhi, Jaipur, Coimbatore, Hyderabad, Dehradun, Kolkata

2026-02-11

Recruiting

Host-Diet-Gut Interaction Post Vegan Diet in Pediatric Autoimmune Hepatitis.

NCT07118657Autoimmune Hepatitis

Institute of Liver and Biliary Sciences, India

Not applicable

New Delhi

2026-02-11

Recruiting

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

NCT07369011Sleep Apnea, Obstructive, Obesity, Overweight

DrugEloralintide

Eli Lilly and Company

Phase 3

800

Bengaluru, Bhubaneswar, Guntur, Nagpur, New Delhi, Pune, Raipur, Rishikesh

2026-02-10

Recruiting

The International Spinal Cord Injury Blood Biomarker Longitudinal Evaluation (I-SCRIBBLE) Study

NCT06839300Spinal Cord Injury

AO Foundation, AO Spine

Observational

260

New Delhi

2026-02-09

Not yet open

Efficacy and Safety of Early Initiation of Midodrine for Control and Prevention of Ascites and Its Related Complications in Acute-on-chronic Liver Failure.

NCT07422948Acute on Chronic Liver Failure

DrugMidodrine

Institute of Liver and Biliary Sciences, India

Not applicable

113

New Delhi

2026-02-05

Recruiting

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

NCT07431281Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Esophageal Cancer

DrugsSonesitatug Vedotin·Zolbetuximab·Rilvegostomig·Leucovorin

AstraZeneca

Phase 3

2,130

Ahmedabad, Bhubaneswar, Hyderabad, Kolkata, Mohali, Mumbai, New Delhi, Varanasi

2026-02-03

Not yet open

Pathogenesis of Chronic Kidney Disease Associated With Metabolic Dysfunction- Associated Fatty Liver Disease (MAFLD) and Treatment Response of Oral Semaglutide.

NCT07391267Chronic Kidney Diseases, MAFLD

DrugSemaglutide

Institute of Liver and Biliary Sciences, India

Not applicable

New Delhi

2026-02-01

Recruiting

Comparison of Weekly Somatrogon to Daily Genotropin in Children Born Small for Gestational Age or With Idiopathic Short Stature.

NCT07226089ISS, SGA

DrugSomatrogon

Rabin Medical Center

Phase 3

254

Maheshra, Navi Mumbai, New Delhi

2026-02-01

Not yet open

Effect of Repetitive Bihemispheric Anodal Transcranial Direct Current Stimulation on Motor Function of Patients With Parkinson's Disease

NCT07395531PARKINSON DISEASE (Disorder), Parkinson Disease

Dr. Ram Manohar Lohia Hospital

Phase 3

New Delhi

2026-02-01

Recruiting

Efficacy and Safety of GL0034 in Overweight or Obese Adults With Type II Diabetes Mellitus

NCT07282743Type II Diabetes Mellitus

DrugGL0034

Sun Pharmaceutical Industries Limited

Phase 2

285

Guntur, Bangalore, Kozhikode, Trivandrum, Kolhāpur, Mumbai, Pune, New Delhi

2026-01-20

Recruiting

Post-marketing Phase 4 Safety & Tolerability Study of Breztri aerosphereTM in Indian Patients With Chronic Obstructive Pulmonary Disease

NCT06531798Moderate to Severe COPD

AstraZeneca

Phase 4

166

Bangalore, Dalgate, Drugjan, Hyderabad, Lucknow, Nagpur, New Delhi

2026-01-20

Recruiting

HYPOfractionated RadioTherapy in Cervical Cancer

NCT07625943Cervical Cancer Squamous Cell, Cervical Cancer

All India Institute of Medical Sciences

Not applicable

396

New Delhi

2026-01-15

Recruiting

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

NCT07253285Overweight, Obesity

DrugsCagrilintide·Semaglutide

Novo Nordisk A/S

Phase 3

460

Guntur, Surat, Bangalore, New Delhi, Delhi, Kanpur, Kolkata, Kolhāpur

2026-01-08

Recruiting

A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

NCT07063745Metastatic Non-small Cell Lung Cancer With MTAP Deletion

DrugsNavlimetostat·Nab-paclitaxel·Pemetrexed·Paclitaxel

Bristol-Myers Squibb

Phase 2/3

590

Bangalore, Bengaluru, Mumbai, Nashik, New Delhi, Varanasi, Hyderabad

2026-01-02

Recruiting

Effect of Whey Protein Versus Egg Albumen Protein Challenge on Blood Ammonia Level in Patients of Decompensated Ethanol Related Cirrhosis.

NCT07299110Decompensated Cirrhosis Ethanol Related

Institute of Liver and Biliary Sciences, India

Not applicable

New Delhi

2025-12-12

Recruiting

Impact of Liver Transplantation on Sexual Life and Function

NCT07268196Chronic Liver Disease and Cirrhosis

Institute of Liver and Biliary Sciences, India

Observational

100

New Delhi

2025-12-07

Recruiting

Time to Post-operative Recovery of Serum Albumin as a Predictor of Outcome in Major Hepato Pancreato Biliary Surgeries

NCT07263061Hepatobiliary Disease, Pancreas Disease, Bile Duct Diseases

Institute of Liver and Biliary Sciences, India

Observational

1,000

New Delhi

2025-12-07

Recruiting

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

NCT07276399Squamous Cell Carcinoma of Head and Neck

DrugsAmivantamab·Cisplatin·Carboplatin·Pembrolizumab

Janssen Research & Development, LLC

Phase 3

600

Chennai, Jaipur, Kolkata, Nashik, New Delhi, Vadodara

2025-12-03

Recruiting

A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)

NCT06937229Alzheimer Disease, Agitation

DrugsKarX-EC·KarXT

Bristol-Myers Squibb

Phase 3

650

Ahmedabad, Hyderabad, Varanasi, Kolkata, Delhi, New Delhi

2025-12-02

Not yet open

Short Course or Long Course Radiotherapy as Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer

NCT07258797Adenocarcinoma of the Rectum

Rajiv Gandhi Cancer Institute & Research Center, India

Not applicable

150

New Delhi

2025-12-01

Not yet open

High-volume Versus Standard Volume Plasma Exchange in Patients With Acute Liver Failure With Cerebral Edema

NCT06515145Acute Liver Failure, Cerebral Edema

Institute of Liver and Biliary Sciences, India

Not applicable

New Delhi

2025-12-01

Active, closed

Pharmacokinetic Study of QL2107 Versus Keytruda® for Adjuvant Therapy of Non-Small Cell Lung Cancer (NSCLC)

NCT07162883Carcinoma, Non-Small-Cell Lung

DrugsKeytruda·Pembrolizumab

Qilu Pharmaceutical Co., Ltd.

Phase 3

146

Surat, Mangalore, Nashik, Thane, New Delhi, Bhubaneswar

2025-11-21

Active, closed

A Study to Learn About How Well BAY 3401016 Works in Adults With Alport Syndrome

NCT07211685Alport Syndrome

Bayer

Phase 2

Ahmedabad, New Delhi, Coimbatore, Kolkata

2025-11-19

Recruiting

Safety of Pregnant Subjects Exposed to Ibrexafungerp Including Infant Outcomes

NCT05908682Vulvovaginitis, Candidal, Vulvovaginal Candidiasis, Candida Infection, Vaginal Candidiasis

GlaxoSmithKline

Observational

100

New Delhi

2025-11-12

Recruiting

A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

NCT07225504Secondary Progressive Multiple Sclerosis (SPMS)

DrugRemibrutinib

Novartis Pharmaceuticals

Phase 3

1,275

Gurugram, Mangalore, Kochi, New Delhi, Chandigarh, Vellore, Hyderabad

2025-11-11

Recruiting

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

NCT07186101Ulcerative Colitis

DrugsZotemtegrast·Mirikizumab

Eli Lilly and Company

Phase 2

252

Ahmedabad, Chennai, Coimbatore, Hubli, Hyderabad, New Delhi, Pune, Rajkot

2025-11-10

Recruiting

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

NCT07100080Non-Small Cell Lung Cancer

DrugsIza-bren·Pemetrexed·Cisplatin·Carboplatin

Bristol-Myers Squibb

Phase 2/3

500

Ahmedabad, Gurugram, Bengaluru, Mumbai, Nagpur, New Delhi, Howrah

2025-11-05

Recruiting

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

NCT07223593Peripheral Arterial Disease

DrugOrforglipron

Eli Lilly and Company

Phase 3

1,205

Aligarh, Jaipur, Kolkata, Kozhikode, Nagpur, Nashik, New Delhi, Rishikesh

2025-10-31

Recruiting

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

NCT07291037Non-small Cell Lung Cancer (NSCLC)

DrugsDato-DXd·Docetaxel

AstraZeneca

Phase 3

400

Bangalore, Kolkata, Mumbai, Nashik, New Delhi

2025-10-31

Not yet open

Safety and Efficacy of Ga68-IAC PET/CT for Diagnosis and Clinical Management in Metastatic Breast Cancer Patients

NCT04480619Angiogenic Breast Cancer

Advanced Imaging Projects, LLC

Phase 1/2

Chandigarh, New Delhi

2025-10-30

Active, closed

A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)

NCT07076121Pancreatic Ductal Adenocarcinoma

DrugsNavlimetostat·Abraxane·Nab-paclitaxel·Gemcitabine

Bristol-Myers Squibb

Phase 2/3

470

Kochi, Mumbai, New Delhi, Bhubaneswar, Hyderabad, Varanasi, Kolkata

2025-10-23

Recruiting

A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

NCT07219173Asthma

DrugBrenipatide

Eli Lilly and Company

Phase 2

531

Bangalore, Bhubaneswar, Chhatrapati Sambhajinagar, Dwārka, Kanpur, New Delhi, Pune, Raipur

2025-10-22

Recruiting

A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

NCT07209761Rifampicin-Resistant Pulmonary Tuberculosis, Multidrug-Resistant Pulmonary Tuberculosis

DrugsPretomanid·Bedaquiline·Linezolid·Moxifloxacin

Otsuka Pharmaceutical Development & Commercialization, Inc.

Phase 3

532

Mumbai, New Delhi, Chennai

2025-10-16

Recruiting

BPIT 5-Week Multi-Site Study: Movement Efficiency, Mobility & Neuromuscular Adaptation

NCT07256717Physical Fitness

MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.

Not applicable

369

Burhānpur, Delhi, New Delhi, Greater Noida, Agra

2025-10-10

Recruiting

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

NCT06989437Cachexia, Metastatic Pancreatic Ductal Adenocarcinoma

DrugPonsegromab

Pfizer

Phase 2/3

982

Mumbai, New Delhi, Jaipur, Kolkata

2025-10-03

Recruiting

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

NCT07144280Non-small Cell Carcinoma, Non-Small Cell Lung Cancer Metastatic, Non-Small Cell Lung Carcinoma

DrugsPF-08046054·Docetaxel

Pfizer

Phase 3

680

Mumbai, Pune, New Delhi, Kolkata, Delhi, Kerala

2025-09-29

Recruiting

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

NCT06926868Breast Neoplasms

DrugsIza-bren·Nab-paclitaxel·Capecitabine·Gemcitabine

Bristol-Myers Squibb

Phase 2/3

600

Mumbai, Nagpur, New Delhi, Chennai, Hyderabad, Varanasi

2025-09-11

Recruiting

Effect of Menstrual Phase on the Anesthetic Efficacy

NCT07306533Pulpitis - Irreversible

Jamia Millia Islamia

Not applicable

150

New Delhi

2025-09-11

Not yet open

National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Single vs Repeated Cycle of Granulocyte Colony-Stimulating Factor (GCSF) & Darbepoetin in Early Decompensated Cirrhosis

NCT07131280Decompensated Cirrhosis

DrugsGcsf·Darbepoetin

Institute of Liver and Biliary Sciences, India

Not applicable

110

New Delhi

2025-09

Recruiting

A Research Study to See How Safe is Eptacog Alfa When Used to Stop Heavy Bleeding in Women After Giving Birth in India

NCT07157423Severe Postpartum Haemorrhage

DrugRecombinant factor VIIa

Novo Nordisk A/S

Phase 4

Belagavi, Mysore, Kozhikode, Mumbai, New Delhi, Jaipur, Udaipur, Hyderabad

2025-08-26

Not yet open

The Efficacy of Intravenous Amino Acids in Reducing the Occurrence of AKI After Live Donor Liver Transplant

NCT07132697Liver Transplant; Complications, AKI - Acute Kidney Injury

Institute of Liver and Biliary Sciences, India

Not applicable

100

New Delhi

2025-08-25

Recruiting

A Study of Guselkumab Administered Subcutaneously in Treatment of Indian Participants With Psoriatic Arthritis (PsA)

NCT07141004Arthritis, Psoriatic

DrugsTremfya·Guselkumab

Johnson & Johnson Private Limited

Phase 4

100

Ahmedabad, Chandigarh, Chennai, Gorakhpur, Hyderabad, Mumbai, New Delhi, Patna

2025-08-12

Active, closed

Study of Monoclonal Antibody Nirsevimab Against Respiratory Syncytial Virus (RSV) in Participants up to 24 Months of Age in India

NCT07109297RSV Immunization

DrugNirsevimab

Sanofi

Phase 4

110

Bengaluru, Jaipur, Kolkata, Nagpur, New Delhi, Pune, Vizianagaram

2025-07-31

Recruiting

A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)

NCT06911502Follicular Lymphoma

DrugsPrednisone/Prednisolone·Golcadomide·Bendamustine·Vincristine

Celgene

Phase 3

400

Bengaluru, Mumbai, New Delhi, Hyderabad

2025-07-28

Recruiting

Study to Assess Adverse Events and Change in Disease Activity of Oral Venetoclax in Combination With Subcutaneous (SC) or Intravenous (IV) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Standard Induction Therapy in India

NCT07044687Acute Myeloid Leukemia

DrugsAzacitidine·Venetoclax

AbbVie

Phase 4

100

Gurgaon, Bengaluru, Thiruvananthapuram, Mumbai, Pune, New Delhi, Bhubaneswar, Chennai

2025-07-24

Recruiting

Left Bundle Branch Area Pacing (LBBAP) PMCF Study

NCT07217392Bradycardia, Right Ventricular Pacing, Heart Failure, Atrial Fibrillation (AF)

Abbott Medical Devices

Not applicable

200

Bangalore, New Delhi, Madurai, Kolkata

2025-07-24

Recruiting

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

NCT06758401Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC)

DrugsSigvotatug vedotin·Pembrolizumab

Pfizer

Phase 3

714

Bengaluru, Mumbai, Pune, Thane, New Delhi, Hyderabad

2025-07-23

Recruiting

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

NCT07011732Alzheimer Disease

DrugsKarX-EC·KarXT

Bristol-Myers Squibb

Phase 3

426

Ahmedabad, Hyderabad, Varanasi, Kolkata, Delhi, New Delhi

2025-07-10

Active, closed

A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD

NCT06981078Chronic Obstructive Pulmonary Disease

DrugVerekitug

Upstream Bio Inc.

Phase 2

666

Hyderabad, Nellore, Vijayawada, Gurgaon, Rohtak, Kolhāpur, Nagpur, New Delhi

2025-07-02

Recruiting

Magnetic Resonance Cholangiopancreatography in Living Liver Donors and Its Relationship With Post Operative Recipient Biliary Complications

NCT07715500Chronic Liver Disease and Cirrhosis, Liver Transplant; Complications, Donor Hepatectomy

Institute of Liver and Biliary Sciences, India

Not applicable

100

New Delhi

2025-07-01

Recruiting

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

NCT07054515Niemann-Pick Type C Disease, GM1 Gangliosidosis, GM2 Gangliosidosis

DrugNizubaglustat

Azafaros B.V.

Phase 3

147

Ernākulam, New Delhi, Jaipur, Vellore

2025-06-30

Active, closed

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of GM1 Gangliosidosis or GM2 Gangliosidosis

NCT07082543Gangliosidoses, GM2, Gangliosidosis, GM1

DrugNizubaglustat

Azafaros B.V.

Phase 3

Ernākulam, New Delhi, Jaipur

2025-06-30

Recruiting

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)

NCT07082725Niemann-Pick Type C Disease

DrugNizubaglustat

Azafaros B.V.

Phase 3

Ernākulam, New Delhi, Jaipur, Vellore

2025-06-30

Recruiting

A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy

NCT06979375Heart Failure

DrugCDR132L

Novo Nordisk A/S

Phase 2

200

Vadodara, Kochi, Mumbai, Nagpur, New Delhi, New Dehli, Ludhiana, Dehradun

2025-06-30

Recruiting

A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

NCT06979362Heart Failure

DrugCDR132L

Novo Nordisk A/S

Phase 2

200

Vadodara, Nagpur, New Delhi, New Dehli, Vijayawada, Chennai, Hyderabad, Dehradun

2025-06-27

Not yet open

A Study to Assess the Effect Probiotic Supplement on Immune Health in Teachers Prone to Upper Respiratory Tract Infection

NCT07033754URTI - Viral Upper Respiratory Tract Infection

Vedic Lifesciences Pvt. Ltd.

Not applicable

100

Vadodara, Nashik, Pune, New Delhi, Varanasi

2025-06-25

Recruiting

A Safety Study of Enfortumab Vedotin in Indian Adults With Urothelial Cancer

NCT06862219Metastatic Urothelial Carcinoma

DrugEnfortumab Vedotin

Astellas Pharma Global Development, Inc.

Phase 4

100

Patna, Kochi, Mumbai, New Delhi, Dumas, Vellore, Varanasi, Kolkata

2025-06-21

Recruiting

Acute Portal Pressure Reduction by Metformin and Carvedilol Compared to Carvedilol Alone in Cirrhosis.

NCT07108075Liver Cirrhosis

DrugsCarvedilol·Metformin

Institute of Liver and Biliary Sciences, India

Not applicable

New Delhi

2025-06-14

Active, closed

A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's Ataxia

NCT06953583Friedreich Ataxia

DrugsOmaveloxolone·Skyclarys

Biogen

Phase 3

255

New Delhi

2025-06-09

Recruiting

Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates

NCT06377397Sepsis, PROM, Preterm (Pregnancy), Early-Onset Neonatal Sepsis, Preterm Premature Rupture of Membrane

Indian Council of Medical Research

Phase 3

1,500

Chandigarh, Rohtak, Bengaluru, Chhatrapati Sambhajinagar, Mumbai, New Delhi, Chennai, Lucknow

2025-06-07

Recruiting

Effect of Single vs Repeated Cycles of a Combination of Granulocyte Colony Stimulating Factor and Darbepoetin vs Standard Medical Treatment on Immunometabolic Profile in Patient With Early Decompensated Cirrhosis.

NCT07002827Decompensated Liver Cirrhosis

DrugsDarbepoetin·Lactulose·Albumin·G-Csf

Institute of Liver and Biliary Sciences, India

Not applicable

New Delhi

2025-06-04

Active, closed

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

NCT07000123Cardiovascular Disease

DrugAZD0780

AstraZeneca

Phase 3

3,103

Belagavi, Dehradun, Kanpur, Kochi, New Delhi

2025-05-28

Recruiting

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

NCT07012395Ulcerative Colitis, Inflammatory Bowel Diseases, Colitis, Colitis, Ulcerative

DrugsSPY001·SPY002·SPY003

Spyre Therapeutics, Inc.

Phase 2

645

New Delhi, Hyderabad, Jaipur, Kochi, Sūrat

2025-05-27

Active, closed

A Study to Assess Safety of Teclistamab in Indian Participants With Relapsed and Refractory Multiple Myeloma

NCT07030517Multiple Myeloma

DrugTeclistamab

Johnson & Johnson Private Limited

Phase 4

Bangalore, Bengaluru, Chandigarh, Jaipur, Kolkata, Mumbai, Nagpur, New Delhi

2025-05-22

Recruiting

A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)

NCT06962800Primary Membranous Nephropathy

DrugsFelzartamab·Tacrolimus

Biogen

Phase 3

180

Hyderabad, Bangalore, Pune, New Delhi, Lucknow, Varanasi, Kolkata, Chandigarh

2025-05-22

Recruiting

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

NCT06935370Heart Failure

DrugsVicadrostat·Dapagliflozin

Boehringer Ingelheim

Phase 3

4,200

Bangalore, Bikaner, Chennai, Chhatrapati Sambhajinagar, Kochi, Kolkata, Nashik, New Delhi

2025-05-20

Recruiting

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

NCT06819891Moderately to Severely Active Crohns Disease

DrugAfimkibart

Hoffmann-La Roche

Phase 3

425

Kurnool, Rajkot, Surat, Kochi, Nagpur (urban), New Delhi, Jaipur, Gachibowli

2025-05-12

Recruiting

A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

NCT06499285Myelodysplastic Syndromes

DrugElritercept

Takeda

Phase 3

225

Ahmedabad, Ernākulam, Mumbai, New Delhi, Ludhiana, Vellore, Ghaziabad, Kolkata

2025-05-06

Active, closed

A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1

NCT06948435Hypertension, Overweight or Obesity

DrugOrforglipron

Eli Lilly and Company

Phase 3

487

Bangalore, Bhubaneswar, New Delhi, Ulhasnagar

2025-04-30

Active, closed

A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)

NCT06948422Hypertension

DrugOrforglipron

Eli Lilly and Company

Phase 3

974

Bangalore, Bhubaneswar, New Delhi, Ulhasnagar

2025-04-30

Active, closed

A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2

NCT06952530Hypertension

DrugOrforglipron

Eli Lilly and Company

Phase 3

487

Bangalore, Bhubaneswar, New Delhi, Ulhasnagar

2025-04-30

Recruiting

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

NCT06875310Carcinoma, Non-Small-Cell Lung

DrugsAdagrasib·Pemetrexed·Keytruda·Cisplatin

Mirati Therapeutics Inc.

Phase 3

630

Visakhapatnam, Ahmedabad, Thiruvananthapuram, Mumbai, New Delhi, Bhubaneswar, Madurai, Hyderabad

2025-04-24

Recruiting

To Study the Clinical Course and Outcomes of Non-electively Hospitalised Patients of Chronic Liver Disease (CLD) With Hepatic or Extra-hepatic Predominant Organ Failure(s) at 6 Months.

NCT07270809Chronic Liver Disease

Institute of Liver and Biliary Sciences, India

Observational

100

New Delhi

2025-04-15

Active, closed

ASCEND CSP IDE Study

NCT06830746Heart Failure, Ventricular Arrythmia

Abbott Medical Devices

Not applicable

414

New Delhi, Trivandrum, Madurai

2025-04-11

Recruiting

The Study of Association of Helicobacter Infections in Biliary Tract Cancers

NCT06909188Biliary Tract Cancer

Institute of Liver and Biliary Sciences, India

Observational

250

New Delhi

2025-03-31

Active, closed

Safety and Immunogenicity of a Mycobacterium Tuberculosis Vaccine MTBVAC in Healthy Indian Adults and Adolescents (BBV169/2024)

NCT06997367Tuberculosis (TB)

Bharat Biotech International Limited

Phase 2

164

Delhi, New Delhi

2025-03-27

Active, closed

Study of Eftilagimod Alfa (Efti) in Combination With Pembrolizumab and Chemotherapy Versus Placebo in Combination With Pembrolizumab and Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (TACTI-004)

NCT06726265Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

DrugsEfti·Pemetrexed·Keytruda·Paclitaxel

Immutep S.A.S.

Phase 3

756

Bangalore, Bhubaneswar, Chennai, Kolkata, New Delhi, Thane, Thiruvananthapuram, Varanasi

2025-03-21

Recruiting

Comparison of Blood Products Required Using Two Different ROTEM Cut-offs Before Invasive Procedures in Cirrhosis and Acute on Chronic Liver Failure (ACLF) Patients With Severe Coagulopathy

NCT06831565Acute-On-Chronic Liver Failure

Institute of Liver and Biliary Sciences, India

Not applicable

790

New Delhi

2025-03-19

Recruiting

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

NCT06819878Moderately to Severely Active Crohns Disease

DrugAfimkibart

Hoffmann-La Roche

Phase 3

600

Kurnool, Rajkot, Surat, Kochi, Nagpur (urban), New Delhi, Jaipur, Gachibowli

2025-03-17

Recruiting

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Newly Diagnosed Active Crohn Disease

NCT06890650Crohn Disease

All India Institute of Medical Sciences

Not applicable

168

Kochi, Mumbai, New Delhi, Ludhiana, Chandigarh, Varanasi

2025-03-15

Recruiting

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Newly Diagnosed Active Ulcerative Colitis

NCT06895252Ulcerative Colitis (UC)

All India Institute of Medical Sciences

Not applicable

220

Kochi, Mumbai, New Delhi, Ludhiana, Chandigarh, Varanasi

2025-03-15

Recruiting

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Ulcerative Colitis on Advanced Therapies

NCT06906445Ulcerative Colitis

All India Institute of Medical Sciences

Not applicable

220

Kochi, Mumbai, New Delhi, Ludhiana, Chandigarh, Varanasi

2025-03-15

Recruiting

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Crohn Disease on Advanced Therapies

NCT06890637Crohns Disease

All India Institute of Medical Sciences

Not applicable

168

Kochi, Mumbai, New Delhi, Ludhiana, Varanasi, Chandigarh

2025-03-15

Recruiting

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

NCT06742723Chronic Kidney Disease and Hypertension

DrugBaxdrostat/dapagliflozin

AstraZeneca

Phase 3

5,000

Bangalore, Belagavi, Hyderabad, Kolkata, Madurai, Mumbai, New Delhi, Pune

2025-03-03

Not yet open

Efficacy and Safety of Therapeutic Plasma Exchange vs Standard Medical Therapy in Severe Autoimmune Hepatitis.

NCT06855667Autoimmune Hepatitis

Institute of Liver and Biliary Sciences, India

Not applicable

New Delhi

2025-03-03

Recruiting

Effects of Advanced Trauma Life Support® on Adult Trauma Patient Outcomes

NCT06321419Wounds and Injuries

Karolinska Institutet

Not applicable

4,320

Dibrugarh, Mumbai, New Delhi, Ludhiana, Dehradun, Kolkata, Chandigarh

2025-02-27

Recruiting

A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

NCT06646276Extensive-Stage Small Cell Lung Cancer

DrugsEtoposide·Atezolizumab·Nivolumab·Carboplatin

Bristol-Myers Squibb

Phase 3

530

Bengaluru, New Delhi, Madurai, Varanasi, Kolkata

2025-02-25

Active, closed

A Study to Evaluate the Efficacy and Safety of JNJ-77242113 (Icotrokinra) in Biologic-naïve Participants With Active Psoriatic Arthritis

NCT06878404Arthritis, Psoriatic

DrugIcotrokinra

Janssen Research & Development, LLC

Phase 3

552

Ahmedabad, Bhubaneswar, Hyderabad, Kolkata, Mumbai, Mysuru, New Delhi, Noida

2025-02-21

Not yet open

Comparative Study of Carvedilol Monotherapy Versus Combination Therapy With Endoscopic Variceal Ligation (EVL) for Primary Prophylaxis of Variceal Bleeding in Patients With Hepatocellular Carcinoma With High-Risk Esophageal Varices

NCT06836778Hepatocellular Carcinoma

DrugCarvedilol

Institute of Liver and Biliary Sciences, India

Not applicable

100

New Delhi

2025-02-20

Recruiting

Standard Volume vs. High Volume Plasma Exchange in Pediatric Acute Liver Failure

NCT06831643Acute Liver Failure

Institute of Liver and Biliary Sciences, India

Not applicable

New Delhi

2025-02-17

Recruiting

Effect of Indianized Version of Mediterranean Diet vs. Low Fat Diet on Hepatic Steatosis in Overweight Children and Adolescent With MASLD

NCT06768216Metabolic Dysfunction-Associated Steatotic Liver Disease

Institute of Liver and Biliary Sciences, India

Not applicable

134

New Delhi

2025-02-15

Not yet open

Efficacy and Safety of Continuous Infusion of Terlipressin vs Bolus Terlipressin in ACLF Patients With Acute Esophageal Variceal Bleed

NCT06815770Acute on Chronic Liver Failure

Institute of Liver and Biliary Sciences, India

Phase 2/3

New Delhi

2025-02-10

Not yet open

Comparison of Efficacy and Safety of Ceftazidime Avibactam Versus Extended Infusions of High Dose Meropenem in Patients of ACLF With Nosocomial Infections.

NCT06818565Acute-On-Chronic Liver Failure

DrugsTeicoplanin·Ceftazidime-avibactam·Meropenem

Institute of Liver and Biliary Sciences, India

Not applicable

150

New Delhi

2025-02-10

Active, closed

A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

NCT06744920Generalized Myasthenia Gravis

DrugRemibrutinib

Novartis Pharmaceuticals

Phase 3

180

Gurugram, Mangalore, Nashik, New Delhi, Ludhiana, Vellore, Hyderabad, Lucknow

2025-02-07

Not yet open

Goal Directed Ammonia Lowering Therapy in Hyperammonemic ACLF Patients With no Overt HE to Reduce Major Adverse Liver Related Outcomes (GOAL Trial)

NCT06808009Acute on Chronic Liver Failure

DrugsLactulose·Rifaximin

Institute of Liver and Biliary Sciences, India

Not applicable

New Delhi

2025-02-05

Not yet open

Compare the Efficacy and Safety of Dabigatran and Enoxaparin in Patients With Portal Vein Thrombosis With Cirrhosis

NCT06818279Portal Vein Thrombosis, Liver Cirrhosis

DrugsDabigatran·Enoxaparin

Institute of Liver and Biliary Sciences, India

Phase 2/3

120

New Delhi

2025-01-31

Not yet open

Comparison of Safety and Efficacy of Tailored Versus Fixed Dose Albumin for the Management of Patients With Cirrhosis and Sepsis Associated Acute Kidney Injury

NCT06809088Liver Cirrhosis, Acute Kidney Injury

DrugAlbumin

Institute of Liver and Biliary Sciences, India

Not applicable

100

New Delhi

2025-01-31

Not yet open

Efficacy of Plasmapheresis in Patients of Drug-Induced Liver Injury (DILI) With Underlying Chronic Liver Disease

NCT06797011Drug Induced Liver Injury, Chronic Liver Disease

Institute of Liver and Biliary Sciences, India

Phase 2/3

New Delhi

2025-01-25

Not yet open

Genetic Polymorphisms Associated With the Risk of Pancreatitis in Patients With Alcohol Related Cirrhosis.

NCT06763198Alcohol-related Liver Disease

Institute of Liver and Biliary Sciences, India

Observational

150

New Delhi

2025-01-25

Recruiting

mHealth India Postnatal Health Intervention Effectiveness

NCT05268588Health Knowledge, Attitudes, Practice, Post Partum Depression, Breastfeeding, Nutrition, Healthy

University of California, San Francisco

Not applicable

2,100

Chandīgarh, Bhopal, New Delhi

2025-01-20

Not yet open

A Randomized Controlled Trial to Assess the Role of Emergent vs Early Endoscopy in Child B and C Cirrhotic Patients With Acute Variceal Bleed (AVB)-EARLY - AVB

NCT06785701Acute Variceal Bleed

Institute of Liver and Biliary Sciences, India

Not applicable

220

New Delhi

2025-01-20

Not yet open

Randomized Controlled Trial of Mycophenolate Mofetil Versus Steroid Therapy in Alcoholic Hepatitis

NCT06789315Alcoholic Hepatitis

DrugsMycophenolate Mofetil·Prednisone

Institute of Liver and Biliary Sciences, India

Not applicable

New Delhi

2025-01-20

Recruiting

Safety of Discontinuing NSBBs in Cirrhotic Patients With Managed Primary Aetiological Factors

NCT06549673Portal Hypertension, Cirrhosis, Varices, Esophageal

Chinese University of Hong Kong

Observational

375

Hyderabad, New Delhi

2025-01-20

Recruiting

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

NCT06609226Sickle Cell Disease, Thalassemia

Novo Nordisk A/S

Phase 3

480

Raipur, Mumbai, Bangalore, Gujarat, Maharashtra, New Delhi

2025-01-10

Active, closed

A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis

NCT06807424Arthritis, Psoriatic

DrugIcotrokinra

Janssen Research & Development, LLC

Phase 3

813

Ahmedabad, Bhubaneswar, Hubballi, Kolkata, Mysuru, New Delhi, Noida, Surat

2025-01-09

Active, closed

Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease

NCT06760637Breast Cancer

DrugsAtirmociclib·Ribociclib·Abemaciclib·Palbociclib

Pfizer

Phase 3

1,035

Surat, Gurugram, Bangalore, Mumbai, Nashik, Pune, Thane, New Delhi

2025-01-06

Not yet open

Thalidomide Versus Argon Plasma Coagulation in Gastric Antral Vascular Ectasia(GAVE)-Related Anaemia in Cirrhosis (TAG Trial)

NCT06772480Liver Cirrhosis, Gastric Antral Vascular Ectasia

DrugThalidomide

Institute of Liver and Biliary Sciences, India

Not applicable

100

New Delhi

2025-01-05

Active, closed

Phase 4 Study to Assess the Safety of Trastuzumab Deruxtecan, in Indian Patients

NCT06429761BREAST CANCER

DrugTrastuzumab deruxtecan

AstraZeneca

Phase 4

100

Bangalore, Delhi, Kochi, Mumbai, New Delhi, Pune, Varanasi

2025-01-02

Recruiting

To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver Surgery

NCT07085806Liver Regeneration

DrugPentoxifylline

Institute of Liver and Biliary Sciences, India

Not applicable

New Delhi

2025-01-01

Recruiting

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

NCT06750094Colorectal Neoplasms

DrugsLeucovorin calcium/Levoleucovorin·Amivantamab·Erbitux·Avastin

Janssen Research & Development, LLC

Phase 3

700

Delhi, Hyderabad, Kolkata, Mumbai, New Delhi, Pune, Varanasi, Vellore

2024-12-12

Recruiting

ICU-related Out of Pocket Expenses (ICOPE)

NCT07439692Cost of ICU, Out of Pocket Expenses

Nat Intensive Care Surveillance - MORU

Observational

354

Mysore, Kochi, Pune, New Delhi, Chennai

2024-12-01

Recruiting

Effect of Perioperative Oral Rifaximin on Early Graft Dysfunction in Adult Living Donor Liver Transplant

NCT06743464Chronic Liver Disease

DrugRifaximin

Institute of Liver and Biliary Sciences, India

Not applicable

100

New Delhi

2024-12-01

Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

NCT06627647Non-squamous Non-small Cell Lung Cancer

DrugsRilvegostomig·Pemetrexed·Keytruda·Cisplatin

AstraZeneca

Phase 3

1,160

Calicut, Delhi, Gūrgaon, Kolkata, Madurai, Mumbai, Nashik, New Delhi

2024-11-27

Recruiting

Stereotactic Body Radiotherapy Boost Versus Simultaneous Integrated Boost to Pelvic Nodes Among Patients Receiving Radical Chemoradiation in Carcinoma Cervix

NCT07585929Stage IIIC

All India Institute of Medical Sciences

Not applicable

150

Delhi, New Delhi

2024-11-20

Active, closed

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

NCT06616194Migraine

DrugRimegepant

Pfizer

Phase 3

636

Gurugram, Mangalore, Nashik, New Delhi

2024-11-15

Recruiting

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

NCT06632457Metabolic Dysfunction Associated Steatohepatitis

Boehringer Ingelheim

Phase 3

1,590

Ahemdabad, Chandigarh, Hyderabad, Afzalgunj, Jaipur, Lucknow, Nagpur, New Delhi, Rohtak

2024-11-12

Not yet open

Daily Versus Alternate Day Plasma Exchange in Wilson Disease With Acute Liver Failure in Children

NCT06698991Acute Liver Failure, Wilson Disease

Institute of Liver and Biliary Sciences, India

Not applicable

New Delhi

2024-11-10

Not yet open

Genetic Variants Associated With the Risk of Gall Stones and Cirrhosis.

NCT06679738Liver Cirrhosis, Gall Stone

Institute of Liver and Biliary Sciences, India

Observational

New Delhi

2024-11-10

Recruiting

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

NCT06632444Metabolic Dysfunction Associated Steatohepatitis (MASH), Liver Fibrosis

Boehringer Ingelheim

Phase 3

1,800

Ahemdabad, Chandigarh, Hyderabad, Afzalgunj, Jaipur, Lucknow, Mohali, Nagpur, New Delhi

2024-10-14

Active, closed

A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

NCT06470048Diffuse Cutaneous Systemic Sclerosis

DrugIanalumab

Novartis Pharmaceuticals

Phase 2

201

Kochi, Mumbai, New Delhi, Jaipur

2024-10-09

Recruiting

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

NCT06561386Non-small Cell Lung Cancer

DrugsRelatlimab·Pemetrexed·Nivolumab·Cisplatin

Bristol-Myers Squibb

Phase 3

1,000

Badsa, Bengaluru, Thiruvananthapuram, Mumbai, New Delhi, Secunderabad, Varanasi, Howrah

2024-10-07

Active, closed

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

NCT06421636Non-Transfusion Dependent Beta-Thalassemia (NTDT)

Regeneron Pharmaceuticals

Phase 2

Ahmedabad, Surat, Kochi, Mumbai, New Delhi, Jaipur

2024-09-30

Recruiting

Effect of Laser Photobiomodulation in Improving Mouth Opening in Oral Submucous Fibrosis

NCT06639009Oral Submucous Fibrosis

Dr. Shalini Gupta

Not applicable

315

New Delhi

2024-09-01

Recruiting

First in Human Multicenter Open Name Dose-increase, Consolidation Method to Study Safety Drug-level in Blood & Drug Metabolism Clinical Activity of Oral JBI-778 in Lung Cancer Patients With, Without Brain Metastasis IDH Mutated WHO Grade 3,4 Recurrent Glioma, Salivary Glands Tumor

NCT07755397NSCLC Patients With EGFR Activating Mutation, Adenoid Cystic Carcinoma Metastatic, Adenoid Cystic Carcinoma of the Head and Neck

Jubilant Therapeutics India Limited

Phase 1

Surat, Bangalore, Mumbai, Nashik, Thane, New Delhi

2024-08-26

Recruiting

Effect of Yoga in Chronic Insomnia

NCT07419152Chronic Insomnia

All India Institute of Medical Sciences

Not applicable

New Delhi

2024-08-14

Recruiting

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

NCT06380751Advanced Breast Cancer

DrugsSaruparib·Camizestrant·Exemestane·Anastrozole

AstraZeneca

Phase 3

788

Delhi, Kolkata, Lucknow, Mumbai, Mysuru, Nagpur, Nashik, New Delhi

2024-08-01

By invitation

Long-term Safety and Tolerability of BHV-7000

NCT06443463Focal Epilepsy

DrugOpakalim

Biohaven Therapeutics Ltd.

Phase 2

660

Hyderabad, Mangalore, Mumbai, Nagpur, New Delhi

2024-07-30

Recruiting

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

NCT06282575Biliary Tract Cancer

DrugsZanidatamab·Durvalumab·Gemcitabine·Cisplatin

Jazz Pharmaceuticals

Phase 3

286

Belagavi, Mumbai, Nashik, Hyderabad, Varanasi, New Delhi

2024-07-19

Recruiting

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

NCT06226883Inflammatory Bowel Diseases, Crohn's Disease

DrugZotemtegrast

Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

Phase 2

385

Ahmedabad, Bhubaneswar, Coimbatore, Jaipur, Kochi, Ludhiana, New Delhi, Pune

2024-07-18

Recruiting

A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

NCT06024746Heart Failure

DrugsFinerenone·Dapagliflozin

Colorado Prevention Center

Phase 3

1,500

Ahmedabad, Bangalore, Nagpur, New Delhi

2024-07-09

Recruiting

Study of WAL0921 in Patients With Glomerular Kidney Diseases

NCT06466135Diabetic Nephropathies, Primary Focal Segmental Glomerulosclerosis, Minimal Change Disease, Primary Immunoglobulin A Nephropathy

Walden Biosciences

Phase 2

Raipur, Nadiād, Vadodara, Bangalore, Pune, Sambhajinagar, New Delhi, Patparganj

2024-07-02

Recruiting

A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis

NCT06080789Acute Pancreatitis

Panafina, Inc.

Phase 2

Kochi, Vellore, Chandigarh, Delhi, New Delhi

2024-06-28

Active, closed

Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma

NCT06356129Large B-cell Lymphoma

DrugsGolcadomide·Vincristine·Doxorubicin·Prednisone

Celgene

Phase 3

850

Belagavi, Kochi, Mumbai, New Delhi, Howrah, New Town

2024-06-19

Recruiting

Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease

NCT05831085Coronary Artery Stenosis

Duk-Woo Park, MD

Not applicable

1,500

Bathinda, Gurugram, New Delhi

2024-06-14

Active, closed

Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)

NCT06305754Non-small Cell Lung Cancer (NSCLC)

DrugsSteroid mouthwash (dexamethasone·Acetaminophen·Sacituzumab tirumotecan·Pemetrexed

Merck Sharp & Dohme LLC

Phase 3

550

Gurugram, Mumbai, New Delhi

2024-06-11

Active, closed

A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)

NCT06472076Lung Cancer, Non-Small Cell

DrugsBelrestotug·Dostarlimab·Pembrolizumab

GlaxoSmithKline

Phase 3

Gokul Shirgoan, Apex Wellness Hospital, Bangalore, Belagavi, Bhubaneswar, Gūrgaon, New Delhi

2024-06-10

Recruiting

Music Therapy for Rehabilitation in Post-stroke Non-fluent Aphasia: the Indian Adaptation

NCT06323330Stroke Rehabilitation, Aphasia, Broca

All India Institute of Medical Sciences

Not applicable

Delhi, New Delhi

2024-06-01

Recruiting

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

NCT06345729Non-small Cell Lung Cancer

DrugsCalderasib·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

348

Mumbai, New Delhi

2024-05-24

Recruiting

Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

NCT06133972Systemic Lupus Erythematosus

DrugIanalumab

Novartis Pharmaceuticals

Phase 3

550

Ahmedabad, Kozhikode, Kolhāpur, Nagpur, Nashik, Pune, New Delhi

2024-05-21

Active, closed

Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

NCT06309966Focal Epilepsy

DrugOpakalim

Biohaven Therapeutics Ltd.

Phase 2/3

390

Hyderabad, Mangalore, Mumbai, Nagpur, New Delhi

2024-05-13

Recruiting

Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer

NCT06350097Non-small Cell Lung Cancer

DrugsDato-DXd·Osimertinib

AstraZeneca

Phase 3

582

Bangalore, Delhi, Hyderabad, Kolkata, Mysuru, Nagpur, Nashik, New Delhi

2024-04-29

Active, closed

Endothelin Receptor Antagonism With Ambrisentan to Treat Hepatorenal Syndrome

NCT06256432Hepatorenal Syndrome, Liver Cirrhosis, Acute Kidney Injury, Ascites Hepatic

DrugsAmbrisentan·Terlipressin

Noorik Biopharmaceuticals AG

Phase 2

Bangalore, Mumbai, New Delhi, Hyderabad, Kanpur, Lucknow

2024-04-17

Active, closed

A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.

NCT06372145Relapsing Multiple Sclerosis, Secondary Progressive Multiple Sclerosis, Progressive Relapsing Multiple Sclerosis

DrugTeriflunomide

Sanofi

Phase 3

2,500

Bengaluru, Chandigarh, Delhi, Gūrgaon, Mangaluru, Nagpur, New Delhi, Thiruvananthapuram

2024-04-16

Not yet open

Lesioning Procedures for Movement Disorders

NCT06352268Dystonia, Parkinson Disease, Essential Tremor

All India Institute of Medical Sciences

Observational

250

New Delhi

2024-04-15

Recruiting

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

NCT06312176Breast Neoplasms

DrugsLiposomal doxorubicin·Abraxane·Xeloda·Sacituzumab tirumotecan

Merck Sharp & Dohme LLC

Phase 3

1,200

Mumbai, New Delhi

2024-04-14

Recruiting

Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

NCT06357533Non-Small Cell Lung Cancer

DrugsRilvegostomig·Dato-DXd·Keytruda·Pembrolizumab

AstraZeneca

Phase 3

675

Chennai, Dwārka, Jaipur, Kolkata, Marg Jaipur, Nagpur, Nashik, New Delhi

2024-04-11

Recruiting

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

NCT06318169Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

DrugPegozafermin

Hoffmann-La Roche

Phase 3

1,350

Guwahati, Allahābād, Kolkata, Bhubaneswar, Gujrāt, Nagpur, New Delhi, Surat

2024-03-13

Active, closed

AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

NCT06346392Gastric Cancer, Gastroesophageal Junction Cancer

DrugsSonesitatug Vedotin·Ramucirumab·Trifluridine/Tipiracil·Apatinib

AstraZeneca

Phase 3

594

Ahmedabad, Hyderabad, Mumbai, New Delhi

2024-03-04

Not yet open

An Open-label Randomized Controlled Trial Comparing the Role of Therapeutic Plasma-exchange in Ameliorating Secondary Organ Dysfunctions in Patients With ACLF and Develop Biomarkers of Treatment Response

NCT06276907Acute on Chronic Liver Failure

Institute of Liver and Biliary Sciences, India

Not applicable

190

New Delhi

2024-03-01

Active, closed

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

NCT05827081Early Breast Cancer

DrugsLeuprolide·Goserelin·Exemestane·Ribociclib

Novartis Pharmaceuticals

Phase 3

1,466

Hyderabad, Bangalore, Mumbai, Pune, New Delhi, Bhubaneswar, Chennai, Kolkata

2024-02-28

Recruiting

Study of Olverembatinib (HQP1351) in Patients With CML-CP

NCT06423911Chronic Myeloid Leukemia, CML, CML, Chronic Phase

DrugsBosutinib·Olverembatinib

Ascentage Pharma Group Inc.

Phase 3

333

Bangalore, Haryāna, Hyderabad, Kolkata, New Delhi, Pune, Thiruvananthapuram

2024-02-05

Recruiting

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

NCT06008197Heart Failure, Acute Heart Failure

DrugsKerendia·Finerenone

Colorado Prevention Center

Phase 3

5,200

Guntur, Vijayawada, Patna, Ahmedabad, Kochi, Nagpur, Nashik, New Delhi

2024-01-17

Active, closed

A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment

NCT06105632Advanced or Metastatic Breast Cancer

DrugsExemestane·Everolimus·Fulvestrant

Pfizer

Phase 2

333

Pune, New Delhi

2024-01-09

Active, closed

Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis

NCT06141486Multiple Sclerosis

DrugFrexalimab

Sanofi

Phase 3

943

Bengaluru, Hyderabad, New Delhi, Shimla

2023-12-27

Active, closed

A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3)

NCT06140836Carcinoma, Non-Small-Cell Lung

DrugsRepotrectinib·Crizotinib

Bristol-Myers Squibb

Phase 3

190

Ahmedabad, Gurugram, Bengaluru, Pune, New Delhi

2023-12-21

Active, closed

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

NCT06141473Multiple Sclerosis

DrugsCholestyramine·Activated Charcoal·Teriflunomide·Frexalimab

Sanofi

Phase 3

1,655

Chandigarh, Hyderabad, Kochi, Nagpur, Nashik, New Delhi, Shimla, Thiruvananthapuram

2023-12-13

Recruiting

Performance Analysis of Hermetic Closed-loop Anesthesia Delivery System

NCT05967403Anesthesia

DrugPropofol

Sir Ganga Ram Hospital

Not applicable

150

New Delhi

2023-12-09

Active, closed

Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)

NCT06109779Biliary Tract Cancer

DrugsGemcitabine/Cisplatin·Rilvegostomig·Teysuno·Capecitabine

AstraZeneca

Phase 3

760

Delhi, Kolkata, Mumbai, Mysuru, New Delhi, Varanasi

2023-12-04

Active, closed

Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents

NCT06120491Metastatic Castration-Sensitive Prostate Cancer

DrugsSaruparib·Zytiga·Xtandi·Abiraterone acetate

AstraZeneca

Phase 3

1,898

Bangalore, Calicut, Kanpur, Kolkata, Nagpur, New Delhi, Pune, Vadodara

2023-11-21

Active, closed

Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension.

NCT06042478Chronic Spontaneous Urticaria

DrugsOmalizumab·Remibrutinib

Novartis Pharmaceuticals

Phase 3

470

Ahmedabad, Bangalore, Belagavi, Mysore, Nagpur, Nashik, New Delhi, Bikaner

2023-11-15

Active, closed

A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

NCT06161571NASH/MASH, NAFLD/MASLD

DrugEfruxifermin

Akero Therapeutics, Inc

Phase 3

700

Surat, Vadodara, Thiruvananthapuram, Dahegaon, Mumbai, Nagpur, Pune, New Delhi

2023-11-10

Active, closed

Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)

NCT05925803Systemic Sclerosis, Scleroderma

AstraZeneca

Phase 3

314

Ahmedabad, Delhi, Gurugram, Hyderabad, Kolkata, Mumbai, Mysuru, New Delhi

2023-11-08

Active, closed

Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)

NCT06087835Chronic Kidney Disease With High Proteinuria

DrugDapagliflozin

AstraZeneca

Phase 3

1,835

Bangalore, Belagavi, Delhi, Nadiād, New Delhi

2023-11-07

Active, closed

A Randomized, Double-blind 2-arm, Followed by an Open-label 1-arm, NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome.

NCT05985915Sjogrens Syndrome

DrugIanalumab

Novartis Pharmaceuticals

Phase 3

612

Ahmedabad, New Delhi

2023-10-27

Active, closed

A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Progressive Pulmonary Fibrosis

NCT06025578Progressive Pulmonary Fibrosis

DrugAdmilparant

Bristol-Myers Squibb

Phase 3

1,057

Ahmedabad, Surat, Belagavi, Bhopal, Nagpur, Pune, New Delhi, Mohali

2023-10-25

Active, closed

ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions

NCT05949684Myelodysplastic Syndromes

DrugsEpoetin Alfa·Reblozyl·Luspatercept

Bristol-Myers Squibb

Phase 3

402

Ahmedabad, Bengaluru, New Delhi, Bhubaneswar

2023-10-24

Recruiting

Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

NCT05755386IC-MPGN

DrugIptacopan

Novartis Pharmaceuticals

Phase 3

106

Bangalore, Nagpur, Pune, New Delhi, Hyderabad

2023-10-02

Not yet open

Efficacy and Safety of Radiofrequency Pallidotomy in the Management of Dystonia

NCT06038097Dystonia

All India Institute of Medical Sciences

Not applicable

New Delhi

2023-10-01

Recruiting

Smartphone Use Restriction as Treatment of Primary Headache

NCT06041997Headache Disorders

All India Institute of Medical Sciences

Not applicable

New Delhi

2023-10-01

Active, closed

Cervical Fixation Surgery Cervical Collar for Management of Hirayama Disease: A Randomized Study

NCT05959980Hirayama Disease

All India Institute of Medical Sciences

Not applicable

New Delhi

2023-10-01

Recruiting

Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)

NCT06079671Locally Advanced Cervical Cancer

DrugVolrustomig

AstraZeneca

Phase 3

800

Calicut, Jaipur, Lucknow, Madurai, Mohali, Nagpur, Nashik, New Delhi

2023-09-22

Active, closed

A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis

NCT06003426Idiopathic Pulmonary Fibrosis

DrugAdmilparant

Bristol-Myers Squibb

Phase 3

1,255

Ahmedabad, Surat, Belagavi, Bhopal, Nagpur, Pune, New Delhi, Mohali

2023-09-14

Recruiting

Onabotulinum Toxin A (Botox) in the Treatment of Pharyngo-esophageal Dysphagia

NCT04695600Transfer Dysphagia, Oropharyngeal Dysphagia, Cricopharyngeus Muscle Dysfunction

DrugsBotulinum toxin type A·Botox

All India Institute of Medical Sciences

Phase 2/3

100

New Delhi

2023-08-11

Active, closed

A Clinical Study to Assess the Efficacy and Safety of Leriglitazone in Adult Male Subjects With Cerebral Adrenoleukodystrophy

NCT05819866Cerebral Adrenoleukodystrophy (cALD)

Minoryx Therapeutics, S.L.

Phase 3

New Delhi

2023-07-12

Recruiting

Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study

NCT06016946Friedreich Ataxia

Friedreich's Ataxia Research Alliance

Observational

3,000

New Delhi

2023-06-28

Active, closed

Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus

NCT05966480SLE

DrugEnvudeucitinib

Alumis Inc

Phase 2

408

New Delhi, Ahmedabad, Bangalore, Bengaluru, Chandigarh, Haryāna, Jaipur, Lucknow

2023-06-26

Active, closed

A Research Study to Evaluate the Efficacy and Safety of Cenerimod in Subjects Suffering From Systemic Lupus Erythematosus

NCT05672576Lupus Erythematosus, Systemic

DrugCenerimod

Viatris Innovation GmbH

Phase 3

451

Ahmedabad, Chennai, Hyderabad, Kolkata, Nagpur, Nashik, New Delhi, Pune

2023-06-26

Active, closed

A Study to Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in India

NCT05891249Anemia

DrugsReblozyl·Luspatercept

Bristol-Myers Squibb

Phase 4

Ahmedabad, New Delhi, Kolkata, Assam, Bangalore, Chandigarh, Delhi, Hyderabad

2023-06-05

Recruiting

Yoga Based Cardiac Rehabilitation in Heart Failure Failure

NCT07817589Heart Failure With Reduced Ejection Fraction, Heart Failure NYHA Class II, Heart Failure NYHA Class III

Centre for Chronic Disease Control, India

Not applicable

3,500

Dharwad, Mysore, Shillong, New Delhi, Ludhiana, Jodhpur, Chennai, Rishikesh

2023-04-24

Active, closed

Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)

NCT05624749Systemic Lupus Erythematosus

DrugIanalumab

Novartis Pharmaceuticals

Phase 3

288

Ahmedabad, Kozhikode, Kolhāpur, Nagpur, Nashik, Pune, New Delhi, Dehradun

2023-04-21

Active, closed

Validating Artificial Intelligence Effectiveness Defined Lung Nodule Malignancy Score in Patients With Pulmonary Nodule.

NCT05817110Lung Malignancy

AstraZeneca

Observational

712

Gurugram, New Delhi, Hyderabad, Bangalore, Chennai, Kolkata, Mumbai, Pune

2023-04-20

Recruiting

A Study of SNP-ACTH (1-39) Gel in Patients With Primary Membranous Nephropathy

NCT05696613Primary Membranous Nephropathy

DrugRituximab

Cerium Pharmaceuticals, Inc.

Phase 3

148

Guntur, Nellore, Raipur, Nadiād, Belagavi, Nagpur, New Delhi, Chandigarh

2023-03-13

Recruiting

A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works

NCT05744921Paroxysmal Nocturnal Hemoglobinuria

DrugsCemdisiran·Pozelimab

Regeneron Pharmaceuticals

Phase 3

202

Kochi, Mumbai, New Delhi, Chandigarh, Jaipur

2023-03-07

Active, closed

A Study to Learn About a New Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People Who Have Advanced Metastatic Breast Cancer

NCT05654623Advanced Breast Cancer

DrugsVepdegestrant·Fulvestrant

Pfizer

Phase 3

624

Gurgaon, Mumbai, Nashik, Thane, New Delhi, Kolkata

2023-03-03

Recruiting

Rare Embryonal Tumors of the Central Nervous System: International Registry

NCT05711992Embryonal Tumor

Immune Oncology Research Institute

Observational

300

New Delhi

2023-02-01

Active, closed

A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2)

NCT05552976Relapsed or Refractory Multiple Myeloma

DrugsMezigdomide·Carfilzomib·Dexamethasone

Bristol-Myers Squibb

Phase 3

606

Gurgaon, Bengaluru, Mumbai, Thane, New Delhi, Mohali, Chennai, Hyderabad

2023-01-10

Active, closed

Phase 2b Study of GSK4532990 in Adults With NASH

NCT05583344Nonalcoholic Fatty Liver Disease, Non-alcoholic Fatty Liver Disease

DrugGSK4532990

GlaxoSmithKline

Phase 2

284

Bhubaneswar, Chandigarh, Coimbatore, Guhawati, Mumbai, Nagpur, New Delhi, Secunderabad

2023-01-02

Active, closed

A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia

NCT05648968Warm Autoimmune Hemolytic Anemia (wAIHA)

DrugIanalumab

Novartis Pharmaceuticals

Phase 3

New Delhi, Madurai, Hyderabad, Lucknow

2022-12-30

Active, closed

CORE-OLE: A Study of Olezarsen (ISIS 678354) Administered Subcutaneously to Participants With Severe Hypertriglyceridemia (SHTG)

NCT05681351Severe Hypertriglyceridemia

DrugOlezarsen

Ionis Pharmaceuticals, Inc.

Phase 3

885

Mangalore, New Delhi

2022-12-13

Recruiting

Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia

NCT05512169ALL, Childhood, Pediatric Cancer, Toxicity, Drug, Adverse Drug Event

University of Geneva, Switzerland

Observational

556

New Delhi, Puducherry

2022-12-01

Active, closed

Dose-finding Study of SAR443122 in Adult Participants With Ulcerative Colitis

NCT05588843Colitis Ulcerative

Sanofi

Phase 2

187

Gūrgaon, Jaipur, Kochi, Ludhiana, New Delhi, Pune, Rajkot, Secunderabad

2022-11-25

Active, closed

An RCT of Mycophenolate Mofetil (MMF) in Fibrotic Hypersensitivity Pneumonitis

NCT05626387Hypersensitivity Pneumonitis

DrugsMycophenolate Mofetil·Prednisolone

Post Graduate Institute of Medical Education and Research, Chandigarh

Phase 4

144

Chandigarh, Hyderabad, Jaipur, Jodhpur, Lucknow, New Delhi, Rishikesh, Vellore

2022-11-23

Active, closed

A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP)

NCT05456191Philadelphia Chromosome-Positive Chronic Myeloid Leukemia

DrugsAsciminib·ABL001·Nilotinib

Novartis Pharmaceuticals

Phase 3

568

Ahmedabad, New Delhi, Chennai, Varanasi, Rishikesh

2022-11-21

Recruiting

Anti-relapse Efficacy and Tolerance Assessment of a Cosmetic Cream for Very Dry, Irritated to Atopic Sensitive Skin.

NCT05575882Atopic Dermatitis, Eczema, Atopic

NAOS Argentina S.A.

Not applicable

100

New Delhi

2022-11-03

Recruiting

A Study of Replagal in Children and Adults With Fabry Disease in India

NCT05067868Fabry Disease

DrugReplagal

Shire

Phase 4

Kolkata, New Delhi

2022-11-01

Active, closed

A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity

NCT05556512Obesity, Overweight

DrugTirzepatide

Eli Lilly and Company

Phase 3

15,374

Ahmedabad, Bikaner, Hyderabad, Lucknow, Ludhiana, Mumbai, Nagpur, New Delhi

2022-10-11

Recruiting

A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

NCT05431088Sickle Cell Disease

DrugOsivelotor

Pfizer

Phase 2/3

389

Raipur, Surat, Vadodara, Nashik, New Delhi, Bhubaneswar

2022-09-22

Active, closed

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

NCT05242484Colitis, Ulcerative

DrugsJNJ-78934804·Golimumab·Guselkumab

Janssen Research & Development, LLC

Phase 2

577

Bangalore, Bhubaneswar, Jaipur, New Delhi, Secunderabad, Surat

2022-09-19

Recruiting

Guideline Oriented Approach To Lipid Lowering In Asia-Pacific

NCT05325034Cardiovascular Diseases, Acute Coronary Syndrome, Atherosclerosis, Hypercholesterolemia

Stephen Nicholls

Not applicable

2,000

New Delhi

2022-09-15

Recruiting

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

NCT05511363Psychosis Associated With Alzheimer's Disease

DrugKarXT

Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Phase 3

410

Ahmedabad, New Delhi, Hyderabad

2022-08-23

Recruiting

Pharmacodynamic Equivalence of the Test and Reference Metered Dose Inhalers (MDIs) Containing Albuterol Sulfate in Adult Patients With Stable Mild Asthma

NCT04912596Mild Asthma

Intech Biopharm Ltd.

Not applicable

148

Ahmedabad, Belagāve, Kolkata, New Delhi, Pune, Ulhasnagar

2022-08-15

Active, closed

Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome

NCT05349214Sjogren Syndrome

DrugIanalumab

Novartis Pharmaceuticals

Phase 3

506

Ahmedabad, Bangalore, Pune, New Delhi

2022-08-04

Recruiting

A Study to Learn More About How Safe Darolutamide is and How Well it Works Under Real World Conditions When Taken in Addition to Standard Androgen Deprivation Therapy (ADT) in Indian Participants With High-risk Non-metastatic Castration-resistant Prostate Cancer (nmCRPC)

NCT05348876Non-metastatic Castration-resistant Prostate Cancer

DrugDarolutamide

Bayer

Phase 4

Nadiād, Bengaluru, Kochi, Thiruvananthapuram, Vellalasseri, Amravati, Mumbai, New Delhi

2022-08-03

Active, closed

A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-PD-1 Compared to Anti-PD-1 Monotherapy as First-Line Treatment in Subjects With Unresectable/Metastatic Melanoma

NCT05732805Melanoma, Melanoma (Skin), Melanoma Stage III, Melanoma Stage IV

Biocad

Phase 3

270

Faridabad, Mangalore, Mumbai, Nagpur, Nashik, New Delhi, Pune, Sangli

2022-08-02

Active, closed

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease

NCT05242471Crohn's Disease

DrugsJNJ-78934804·Golimumab·Guselkumab

Janssen Research & Development, LLC

Phase 2

703

Ahmedabad, Bengaluru, Bhubaneswar, Chennai, Gūrgaon, Hyderabad, Mumbai, New Delhi

2022-07-22

Active, closed

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

NCT05296798Locally Advanced or Metastatic Breast Cancer

DrugsPhesgo·Giredestrant·Pertuzumab·Trastuzumab

Hoffmann-La Roche

Phase 3

922

Bangalore, Mumbai, Pune, New Delhi, Kolkata

2022-07-18

Active, closed

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events

NCT05360446Coronary Artery Disease

DrugInclisiran sodium

Novartis Pharmaceuticals

Phase 3

610

Bangalore, New Delhi, Chennai, Coimbatore, Lucknow, Dehradun

2022-07-08

Recruiting

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) International Registry

NCT05430971Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Immune Oncology Research Institute

Observational

200

New Delhi

2022-07-01

Active, closed

A Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)

NCT05374512Breast Cancer

DrugsEribulin·Dato-DXd·Nab-paclitaxel·Capecitabine

AstraZeneca

Phase 3

644

Bangalore, Jaipur, Kolkata, Nagpur, Nashik, New Delhi, Puducherry, Vadodara

2022-05-16

Recruiting

Evaluation of Propofol Dosing Based on Total Body Weight Using Closes-loop Anaesthesia Delivery System

NCT05305313Obesity, Morbid, Anesthesia, Propofol

DrugPropofol

Sir Ganga Ram Hospital

Phase 4

New Delhi

2022-04-19

Active, closed

Evaluate Durvalumab and Tremelimumab +/- Lenvatinib in Combination With TACE in Patients With Locoregional HCC

NCT05301842Hepatocellular Carcinoma

DrugsTremelimumab·Durvalumab·Lenvatinib

AstraZeneca

Phase 3

760

Ahmedabad, Bangalore, Delhi, Hyderabad, Jaipur, Kolkata, Mumbai, New Delhi

2022-03-28

Active, closed

Study of Capivasertib + Docetaxel vs Placebo + Docetaxel as Treatment for Metastatic Castration Resistant Prostate Cancer (mCRPC)

NCT05348577Prostate Cancer

DrugsCapivasertib·Docetaxel

AstraZeneca

Phase 3

1,035

Bikaner, Meerut, Mohali, New Delhi

2022-03-25

Recruiting

TAF (Tenofovir Alafenamide) for Preventing Progression of Liver Disease in Non-cirrhotic Chronic HBV Infection With Normal ALT and Low Viral Load.

NCT05195450Non-cirrhotic, Chronic Hepatitis B

DrugTenofovir alafenamide fumarate

Institute of Liver and Biliary Sciences, India

Not applicable

200

New Delhi

2022-02-23

Active, closed

Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis

NCT05201638Multiple Sclerosis, Relapsing-Remitting

DrugIMU-838

Immunic AG

Phase 3

1,100

Chandigarh, Haryāna, Lucknow, New Delhi, Punjābi Bāgh, Raipur

2022-01-12

Active, closed

Lutetium 177Lu-Edotreotide Versus Best Standard of Care in Well-differentiated Aggressive Grade-2 and Grade-3 GastroEnteroPancreatic NeuroEndocrine Tumors (GEP-NETs) - COMPOSE

NCT04919226Neuroendocrine Tumors

DrugsFOLFOX (Folinic acid·Everolimus·Fluorouracil·Oxaliplatin

ITM Solucin GmbH

Phase 3

259

Bangalore, New Delhi, Mumbai

2021-12-21

Active, closed

A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC)

NCT04819100Carcinoma, Non-Small-Cell Lung

DrugSelpercatinib

Eli Lilly and Company

Phase 3

152

Thiruvananthapuram, Mumbai, Nagpur, Nashik, New Delhi

2021-12-20

Active, closed

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-1)

NCT05147220Relapsing Multiple Sclerosis

DrugsTeriflunomide·Remibrutinib

Novartis Pharmaceuticals

Phase 3

1,000

Mangalore, Mumbai, Nashik, New Delhi, Chandigarh, Ludhiana, Lucknow, Dehradun

2021-12-16

Active, closed

Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure)

NCT04954859Hepatitis B

DrugBepirovirsen

GlaxoSmithKline

Phase 2

366

Belagavi, Coimbatore, Hyderabad, Kanchan Bagh Hyderabad, Mumbai, New Delhi, Pune, Surat

2021-12-14

Active, closed

A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis

NCT05070858Generalized Myasthenia Gravis

DrugsCemdisiran·Pozelimab

Regeneron Pharmaceuticals

Phase 3

288

Guntur, Surat, Panjagutta, Udupi, Kochi, Pune, Parel, New Delhi

2021-12-14

Active, closed

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-2)

NCT05156281Relapsing Multiple Sclerosis

DrugsTeriflunomide·Remibrutinib

Novartis Pharmaceuticals

Phase 3

1,007

Kochi, Pune, New Delhi, Amritsar, Hyderabad, Lucknow, Kolkata

2021-12-13

Recruiting

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

NCT04892173Carcinoma, Squamous Cell

DrugsJNJ-90301900·Erbitux·Cetuximab

Johnson & Johnson Enterprise Innovation Inc.

Phase 3

500

Bangalore, Chennai, Madurai, Mumbai, Nashik, New Delhi, Pune, Vijayawada

2021-12-10

Active, closed

A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

NCT05152147Gastric Neoplasms, Gastroesophageal Adenocarcinoma, Esophageal Adenocarcinoma

DrugsZanidatamab·Herceptin·Trastuzumab·Adrucil

Jazz Pharmaceuticals

Phase 3

920

Bhubaneswar, Gūrgaon, Hyderabad, New Delhi, Patna, Vijayawada

2021-12-02

Recruiting

HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial

NCT04743765Hip Fractures, Myocardial Injury

Population Health Research Institute

Not applicable

1,100

Bangalore, Alappuzha, Trivandrum, New Delhi, Puducherry

2021-11-22

Active, closed

Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis

NCT05134441Multiple Sclerosis

DrugIMU-838

Immunic AG

Phase 3

1,121

Bangalore, Mangalore, Nagpur, New Delhi, Pune, Shimla, Varanasi

2021-11-18

Active, closed

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

NCT04958265Atypical Hemolytic Uremic Syndrome

DrugCrovalimab

Hoffmann-La Roche

Phase 3

Ahmedabad, Gurgaon, New Delhi

2021-11-17

Active, closed

A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure

NCT04988295Carcinoma, Non-Small-Cell Lung

DrugsLazertinib·Amivantamab·Pemetrexed·Carboplatin

Janssen Research & Development, LLC

Phase 3

776

Bangalore, Gurugram, Kolkata, Mumbai, Nashik, New Delhi, Pune, Thane

2021-11-17

Active, closed

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer

NCT04940052Differentiated Thyroid Cancer (DTC)

DrugsDabrafenib·Trametinib

Novartis Pharmaceuticals

Phase 3

153

Hisar, New Delhi, Chennai

2021-11-15

Active, closed

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

NCT05113251Breast Neoplasms, Breast Cancer, HER2-positive Early Breast Cancer

DrugsHerzuma·Perjeta·Herceptin·Adriamycin

AstraZeneca

Phase 3

927

Gūrgaon, Howrah, Nagpur, Nashik, New Delhi, Raipur, Rishikesh, Surat

2021-10-25

Active, closed

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

NCT04861259Atypical Hemolytic Uremic Syndrome

DrugCrovalimab

Hoffmann-La Roche

Phase 3

New Delhi

2021-10-22

Active, closed

A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

NCT04895696Systemic Lupus Erythematosus

DrugAfimetoran

Beeline Medicines Corporation

Phase 2

248

Ahmedabad, Gurugram, Bengaluru, New Delhi, Secunderabad

2021-10-11

Active, closed

Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis

NCT04926818Multiple Sclerosis (MS)

DrugsSiponimod·Fingolimod·Ofatumumab

Novartis Pharmaceuticals

Phase 3

129

New Delhi, Lucknow, Kolkata

2021-10-05

Active, closed

A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases

NCT04603807Carcinoma, Non-Small-Cell Lung

DrugsEntrectinib·Crizotinib

Hoffmann-La Roche

Phase 3

217

Kozhikode, Mumbai, New Delhi, Varanasi, Kolkata

2021-09-30

Recruiting

A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

NCT04557462Primary IgA Nephropathy

DrugIptacopan

Novartis Pharmaceuticals

Phase 3

540

Bangalore, New Delhi, Hyderabad

2021-09-20

Recruiting

Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

NCT04817618C3G

DrugIptacopan

Novartis Pharmaceuticals

Phase 3

New Delhi, Hyderabad, Lucknow, Dehradun

2021-07-28

Recruiting

Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs

NCT04613921Liver Diseases, Liver Cirrhosis, Acute-On-Chronic Liver Failure, Liver Transplant; Complications

European Foundation for Study of Chronic Liver Failure

Observational

3,000

Bengaluru, Mumbai, New Delhi, Jaipur, Chennai, Gurugramam, Kochi, Secunderabad

2021-07-08

Active, closed

D9319C00001- 1L OC Mono Global RCT

NCT04884360Ovarian Cancer

DrugOlaparib

AstraZeneca

Phase 3

366

Gūrgaon, Jaipur, Kolkata, Madurai, Namakkal, Nashik, New Delhi

2021-05-31

Active, closed

Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC

NCT04821622Prostate Cancer

DrugsTalazoparib·Enzalutamide

Pfizer

Phase 3

599

Surat, Gurugram, Mumbai, Pune, New Delhi, Meerut, Kolkata

2021-05-12

Active, closed

Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292)

NCT04862663Locally Advanced (Inoperable) or Metastatic Breast Cancer

DrugsCapivasertib·Ribociclib·Abemaciclib·Palbociclib

AstraZeneca

Phase 3

893

Bangalore, Mohali, Mysuru, Nagpur, New Delhi, Vadodara, Varanasi

2021-05-10

Active, closed

A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy

NCT04873362Breast Cancer

DrugsTrastuzumab emtansine·Herceptin·Tecentriq·Trastuzumab

Hoffmann-La Roche

Phase 3

1,188

Ahmedabad, Bangalore, Mumbai, Nashik, Pune, New Delhi, North WEST Delhi, Ratnagiri Kilminnal

2021-05-04

Active, closed

Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)

NCT04784715Breast Cancer; HER2-positive; Metastatic

DrugsPertuzumab·Trastuzumab deruxtecan·Trastuzumab

AstraZeneca

Phase 3

1,157

Ahmedabad, Bangalore, Bengaluru, Calicut, Gūrgaon, Mysuru, Nashik, New Delhi

2021-04-26

Active, closed

A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

NCT04576156Myelofibrosis

DrugImetelstat Sodium

Geron Corporation

Phase 3

327

Surat, Bangalore, Bengaluru, New Delhi, Gūrgaon, Bhubaneswar, Kolkata, Pune

2021-04-12

Active, closed

Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

NCT04586023Relapsing Multiple Sclerosis

DrugsFenebrutinib·Teriflunomide

Hoffmann-La Roche

Phase 3

751

Ahmedabad, Mumbai, Pune, New Delhi, Ludhiana, Vadapalani, Chandigarh

2021-03-24

Active, closed

SCALE KIDS: Research Study to Look at How Well a New Medicine is at Lowering Weight in Children With Obesity

NCT04775082Obesity

DrugLiraglutide

Novo Nordisk A/S

Phase 3

Guntur, New Delhi

2021-03-04

Recruiting

sFlt1/PlGF and Planned Delivery to Prevent Preeclampsia at Term.

NCT04766866Preeclampsia, Intrauterine Growth Restriction, Maternal Hypertension, Neonatal Outcome

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Not applicable

9,132

New Delhi

2021-03-02

Active, closed

Galinpepimut-S Versus Investigator's Choice of Best Available Therapy for Maintenance in AML CR2/CRp2

NCT04229979Acute Myeloid Leukemia

DrugsGm-Csf·Sargramostim·Ara-C·Decitabine

Sellas Life Sciences Group

Phase 3

127

Kannur, Hyderabad, Ludhiāna, New Delhi, Patna

2021-02-08

Active, closed

A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)

NCT04624659Sickle Cell Disease

DrugEtavopivat

Forma Therapeutics, Inc.

Phase 3

450

Mumbai, Hyderabad, Bangalore, Cutack, New Delhi

2021-01-29

Recruiting

Incidence of Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Surgery

NCT04707794Postoperative Delirium

DrugsDesflurane·Sevoflurane

Sir Ganga Ram Hospital

Observational

270

New Delhi

2021-01-14

Recruiting

Secukinumab Open Label Roll-over Extension Protocol

NCT04638647Autoimmunity, Inflammation

DrugSecukinumab

Novartis Pharmaceuticals

Phase 4

1,000

Surat, Bangalore, Mumbai, Nashik, New Delhi, Hyderabad

2020-12-22

Active, closed

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

NCT04607421Neoplasms

DrugsEncorafenib·Zirabev·Erbitux·Xeloda

Pfizer

Phase 3

841

Mumbai, Pune, Thane, New Delhi, Jaipur

2020-12-21

Active, closed

A Study of Osimertinib With or Without Chemotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer

NCT04351555Non-Small Cell Lung Cancer

DrugsTagrisso·Osimertinib·Pemetrexed·Cisplatin

AstraZeneca

Phase 3

358

Mumbai, Namakkal, New Delhi, Varanasi

2020-12-16

Active, closed

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

NCT04658862Urinary Bladder Neoplasms

DrugsTAR-200·Cetrelimab·Gemcitabine·Cisplatin

Janssen Research & Development, LLC

Phase 3

518

Amravati, Bangalore, Bikaner, Nashik, New Delhi, Patna, Pune

2020-12-07

Active, closed

A Study of Galcanezumab (LY2951742) in Participants 12 to 17 Years of Age With Chronic Migraine

NCT04616326Chronic Migraine

DrugGalcanezumab

Eli Lilly and Company

Phase 3

312

Ahmedabad, Gurugram, Kanpur, Mangalore, Nagpur, New Delhi, Pune

2020-11-25

Active, closed

A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions

NCT04538664Carcinoma, Non-Small-Cell Lung

DrugsAmivantamab·Pemetrexed·Carboplatin

Janssen Research & Development, LLC

Phase 3

308

Hyderabad, Kolkata, Mumbai, Nashik, New Delhi, Pune

2020-10-13

Active, closed

Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer

NCT04494425Advanced or Metastatic Breast Cancer

DrugsTrastuzumab deruxtecan·Nab-paclitaxel·Capecitabine·Paclitaxel

AstraZeneca

Phase 3

866

Bengaluru, Calicut, Kolkata, Marg Jaipur, New Delhi, Surat, Thiruvananthapuram

2020-07-24

Active, closed

A Study to Compare Safety and Efficacy of High Doses of Eteplirsen in Participants With Duchenne Muscular Dystrophy (DMD) (MIS51ON)

NCT03992430Muscular Dystrophy, Duchenne

DrugEteplirsen

Sarepta Therapeutics, Inc.

Phase 3

160

Ahmedabad, Bengaluru, Hyderabad, Madurai, New Delhi, Pune, Vellore

2020-07-13

Active, closed

A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease

NCT04232553Crohn's Disease

DrugMirikizumab

Eli Lilly and Company

Phase 3

996

Chandigarh, Surat, Pune, New Delhi, Ludhiana, Jaipur, Chennai

2020-06-22

Recruiting

Randomised Evaluation of COVID-19 Therapy

NCT04381936Pneumonia

DrugsConvalescent plasma·Sotrovimab·Lopinavir / Ritonavir·Molnupiravir

University of Oxford

Phase 3

70,000

New Delhi

2020-03-19

Active, closed

A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA)

NCT04088396Systemic Juvenile Idiopathic Arthritis

DrugsBaricitinib·Tocilizumab

Eli Lilly and Company

Phase 3

New Delhi

2020-02-12

Active, closed

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitors

NCT04083781Haemophilia A With Inhibitors, Haemophilia B With Inhibitors

DrugConcizumab

Novo Nordisk A/S

Phase 3

134

Bangalore, Pune, New Dehli, Ranipet, New Delhi

2019-10-21

Recruiting

Alloplastic Total Temporomandibular Joint (TMJ) Replacement Registry

NCT03991728Temporomandibular Joint Disorders

AO Innovation Translation Center

Observational

200

Bangalore, New Delhi

2019-10-15

Active, closed

Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumor, Including a Cohort Expansion in Esophageal Cancer.

NCT03983954ER+ Breast Cancer, Ovarian Cancer, Cervical Squamous Cell Carcinoma, Pancreatic Adenocarcinoma

NeoTX Therapeutics Ltd.

Phase 1

120

Ahmedabad, Jhajjar, New Delhi, Udaipur, Hyderabad

2019-10-10

Active, closed

SyncAV Post-Market Trial

NCT04100148Congestive Heart Failure

Abbott Medical Devices

Not applicable

1,686

Hyderabad, Ahmedabad, Bangalore, Gūrgaon, New Delhi

2019-10-03

Active, closed

A Study of Osimertinib With or Without Chemotherapy as 1st Line Treatment in Patients With Mutated Epidermal Growth Factor Receptor Non-Small Cell Lung Cancer (FLAURA2)

NCT04035486Non-Small Cell Lung Cancer

DrugsPemetrexed/Cisplatin·Pemetrexed/Carboplatin·Osimertinib

AstraZeneca

Phase 3

587

Belagavi, Bengaluru, Gūrgaon, Kolkata, New Delhi, Pune

2019-07-02

Active, closed

Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC

NCT03997123Triple Negative Breast Neoplasms

DrugsCapivasertib·Paclitaxel

AstraZeneca

Phase 3

923

Bangalore, Gūrgaon, Kolkata, Mumbai, Mysuru, Nagpur, Nashik, New Delhi

2019-06-25

Recruiting

A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

NCT03633708Secondary Hyperparathyroidism, Chronic Kidney Disease

DrugEtelcalcetide

Amgen

Phase 3

Bangalore, Belagavi, New Delhi, Kolkata

2019-04-29

Active, closed

Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1)

NCT03875235Biliary Tract Neoplasms

DrugDurvalumab

AstraZeneca

Phase 3

810

Gūrgaon, Kolkata, Mumbai, New Delhi

2019-04-16

Recruiting

A Study of Baricitinib in Participants From 1 Year to Less Than 18 Years Old With Juvenile Idiopathic Arthritis

NCT03773965Juvenile Idiopathic Arthritis

DrugBaricitinib

Eli Lilly and Company

Phase 3

190

Chennai, New Delhi, Vellore

2019-04-05

Recruiting

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

NCT03813407Hyperkalaemia

DrugPumitamig

AstraZeneca

Phase 3

140

Bhubaneswar, Gūrgaon, New Delhi

2019-04-02

Recruiting

Comparison of Anaesthesia Requirement for Ventilation With Endotracheal Tube Versus Proseal Laryngeal Mask Airway

NCT03812718Cholelithiases, Cholecystolithiasis

Sir Ganga Ram Hospital

Not applicable

160

New Delhi

2019-03-04

Recruiting

PMZ-1620 (Sovateltide) in Patients of Acute Spinal Cord Injury

NCT04054414Acute Spinal Cord Injury

Pharmazz, Inc.

Phase 2

Belagavi, Kolkata, Lucknow, Nagpur, New Delhi

2019-01-10

Active, closed

Osimertinib Plus Savolitinib in EGFRm+/MET+ NSCLC Following Prior Osimertinib

NCT03778229Carcinoma

DrugsSavolitinib·Osimertinib

AstraZeneca

Phase 2

367

Bangalore, Chennai, Kolkata, New Delhi

2019-01-09

Active, closed

Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

NCT03650114Relapsing Multiple Sclerosis

Drugs13-valent pneumococcal conjugate vaccine·23-valent pneumococcal polysaccharide vaccine·Ofatumumab

Novartis Pharmaceuticals

Phase 3

1,882

Mangalore, Kochi, Mumbai, Pune, New Delhi, Chandigarh, Hyderabad, Howrah

2018-12-28

Active, closed

Study of Durvalumab Given With Chemotherapy, Durvalumab in Combination With Tremelimumab Given With Chemotherapy, or Chemotherapy in Patients With Unresectable Urothelial Cancer

NCT03682068Unresectable Locally Advanced Urothelial Cancer, Metastatic Urothelial Cancer

DrugsTremelimumab·Durvalumab·Gemcitabine·Cisplatin

AstraZeneca

Phase 3

1,246

Gūrgaon, Hubli, Kolkata, Mysuru, Nagpur, Nashik, New Delhi, Pune

2018-09-27

Active, closed

The Minimally Invasive Coronary Surgery Compared to STernotomy Coronary Artery Bypass Grafting Trial

NCT03447938Coronary Artery Disease

Ottawa Heart Institute Research Corporation

Not applicable

176

Bangalore, New Delhi

2018-09-01

Active, closed

A Global Study to Assess the Effects of Osimertinib Following Chemoradiation in Patients With Stage III Unresectable Non-small Cell Lung Cancer (LAURA)

NCT03521154Non Small Cell Lung Cancer (Stage III)

DrugOsimertinib

AstraZeneca

Phase 3

216

Bangalore, Gūrgaon, Hubli, Karamsad, Kolkata, Nashik, New Delhi

2018-07-19

Recruiting

Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

NCT03295981Giant Cell Tumor of Bone

DrugsZoledronate·Zoledronic Acid

St. Louis University

Phase 3

120

New Delhi

2018-05-03

By invitation

International Registry of Congenital Portosystemic Shunt (IRCPSS)

NCT06041906Congenital Portosystemic Shunt, CPSS (Congenital Portosystemic Shunt)

Prof. Valérie Mc Lin

Observational

500

Kochi, New Delhi

2018-04-26

Active, closed

A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

NCT03466411Crohn's Disease

DrugsGuselkumab 1·Guselkumab 2·Guselkumab 3·Ustekinumab

Janssen Research & Development, LLC

Phase 2/3

1,409

Jaipur, New Delhi, Noida, Rajkot, Surat

2018-04-13

Active, closed

A Study of Galcanezumab (LY2951742) in Participants 6 to 17 Years of Age With Episodic Migraine

NCT03432286Episodic Migraine

DrugGalcanezumab

Eli Lilly and Company

Phase 3

533

Mangalore, Nagpur, New Delhi, Pune

2018-03-14

Active, closed

Efficacy Of Bovine Colostrum In The Treatment Of Severe Alcohol-Associated Hepatitis: A Randomized Controlled Trial

NCT02473341Alcoholic Hepatitis

Dayanand Medical College and Hospital

Phase 3

174

Ludhiana, Chandigarh, Hyderabad, Jaipur, New Delhi

2017-11-14

Active, closed

A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer

NCT02763566Breast Cancer

DrugsAnastrozole·Abemaciclib·Letrozole·Fulvestrant

Eli Lilly and Company

Phase 3

463

Ahmedabad, Bangalore, Mumbai, Pune, New Delhi, Ranipet, Kolkata

2016-12-05

Active, closed

Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection

NCT02932150Chronic Hepatitis B

Gilead Sciences

Phase 2

150

Kolkata, Lucknow, Mumbai, Nagpur, New Delhi, Surat, Varanasi

2016-11

Recruiting

Trial Evaluating Role of Post Mastectomy Radiotherapy in Women With Node Negative Early Breast Cancer

NCT02992574Breastcancer

Tata Memorial Centre

Not applicable

1,022

Chandigarh, Kolhāpur, Mumbai, Delhi, New Delhi, Jaipur

2016-05-27

Active, closed

Study of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE)

NCT02542293Non Small Cell Lung Carcinoma NSCLC

DrugsTremelimumab·Durvalumab·Pemetrexed·Gemcitabine

AstraZeneca

Phase 3

953

Ahmedabad, Bangalore, Chennai, Gūrgaon, Karamsad, New Delhi

2015-11-03

Active, closed

Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

NCT02227251Diffuse Large B-cell Lymphoma

DrugSelinexor

Karyopharm Therapeutics Inc

Phase 2

244

Patna, Vadapalani, Delhi, Thiruvananthapuram, Mumbai, Pune, New Delhi, Bhubaneswar

2014-11

Active, closed

A Study of Intravesical BCG in Combination With ALT-803 in Patients With Non-Muscle Invasive Bladder Cancer

NCT02138734Non-muscle Invasive Bladder Cancer

DrugAnktiva

ImmunityBio, Inc.

Phase 1/2

369

Visakhapatnam, Adyār, Ahmedabad, Chhatrapati Sambhajinagar, Nagpur, Pune, Mumbai, New Delhi

2014-07-21

Recruiting

Product Surveillance Registry

NCT01524276Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders

Medtronic

Observational

100,000

Jaipur, Hyderabad, Bangalore, Bengaluru, Chennai, Gūrgaon, Kochi, New Delhi

2012-01

Recruiting

Carvedilol for Pre-primary Prophylaxis of Esophageal Varices in Cirrhosis

NCT01212250Cirrhosis

DrugCarvedilol

Institute of Liver and Biliary Sciences, India

Not applicable

132

New Delhi

2010-09-01

Active, closed

FA Clinical Outcome Measures

NCT03090789Friedreich Ataxia, Neuro-Degenerative Disease

Friedreich's Ataxia Research Alliance

Observational

2,000

New Delhi

2001-01-01

Recruiting

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

NCT00271180Arrhythmia, Bradycardia, Heart Failure, Sinus Tachycardia

Medtronic

Observational

20,000

Bangalore, Chennai, Gūrgaon, Hyderabad, Jaipur, Kochi, New Delhi, Vadapalani

1983-01

Cite this view

Priya Life Science (2026). Clinical trial register: studies with an Indian investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 7 November 2026. https://priyalifescience.com/clinical-trials-india/city/new-delhi

Query this register directly

GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in India and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 1,120 studies in total at the last sync on 07 Nov 2026, 03:16 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 339 of those studies with a site in New Delhi.

How many clinical trials are recruiting in New Delhi?

160 of the 339 studies on this page are recruiting new participants as of the 07 Nov 2026, 03:16 UTC sync. A further 51 have not yet opened recruitment, 126 are active but closed to new participants, and 2 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (New Delhi), 339 studies
Phase	Studies	Recruiting	Share
Phase 3	171	70	50.4%
Not applicable	65	37	19.2%
Observational	34	22	10%
Phase 2	34	14	10%
Phase 4	18	9	5.3%
Phase 2/3	13	7	3.8%
Phase 1	2	1	0.6%
Phase 1/2	2	0	0.6%

Most active sponsors

Lead sponsors with the most studies (New Delhi)
Lead sponsor	Studies	Recruiting
Institute of Liver and Biliary Sciences, India	47	20
AstraZeneca	39	15
Novartis Pharmaceuticals	21	6
Eli Lilly and Company	19	7
Bristol-Myers Squibb	17	8
All India Institute of Medical Sciences	16	10
Pfizer	13	7
Janssen Research & Development, LLC	11	3
Novo Nordisk A/S	10	8
Hoffmann-La Roche	9	3

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.