A Study to Assess Safety of Teclistamab in Indian Participants With Relapsed and Refractory Multiple Myeloma
Condition(s) studied
Investigational drug(s) / intervention(s)
Teclistamab: Teclistamab will be administered subcutaneously.
Study summary
The purpose of this study is to assess the safety of teclistamab in routine clinical practice when given as monotherapy in Indian participants with relapsed and refractory multiple myeloma (RRMM) (that is, a blood cancer that comes back after treatment or does not respond to treatment) who have previously received at least 3 prior lines of therapy including an immunomodulatory agent, a proteasome inhibitor and an anti-cluster of differentiation (CD)38 antibody (is a protein that fights infection) and whose disease have progressed on the last therapy.
Eligibility
Primary outcome measure(s)
- Number of Participants with Treatment-Emergent Adverse Events (TEAE)s — Up to approximately 2 years 1 month
An adverse event (AE) is any untoward medical occurrence in a participant participating in a clinical study that does not necessarily have a causal relationship with the intervention under study. TEAEs are AEs with onset during the treatment or that are a consequence of a preexisting condition that has worsened since the first dose of study treatment through the day of last dose plus 30 days or prior to the start of subsequent anticancer therapy, whichever is earlier, or any AE that is considered treatment-related regardless of the start date of the event. TEAEs reported will include all serious and non-serious adverse events.
Trial sites (12)
| Facility | City | Region | Status |
|---|---|---|---|
| M S Ramaiah Medical College and Hospital | Bangalore | India | |
| St. Johns Medical College And Hospital | Bengaluru | India | |
| Post Graduate Institute of Medical Education And Research PGIMER | Chandigarh | India | |
| Bhagwan Mahaveer Cancer Hospital & Research Centre | Jaipur | India | |
| Tata Medical Center | Kolkata | India | |
| Tata Memorial Hospital | Mumbai | India | |
| KIMS-Kingsway Hospitals | Nagpur | India | |
| All India Institute of Medical Sciences | New Delhi | India | |
| Rajiv Gandhi Cancer Institute & Research Centre | New Delhi | India | |
| Jawaharlal Institute of Postgraduate Medical Education and Research | Puducherry | India | |
| Christian Medical College | Ratnagiri Kilminnal | India | |
| Regional Cancer Centre | Thiruvananthapuram | India |
More Johnson & Johnson Private Limited trials in India
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07030517 on ClinicalTrials.gov ↗ ← All trials in India