Time to Post-operative Recovery of Serum Albumin as a Predictor of Outcome in Major Hepato Pancreato Biliary Surgeries

NCT07263061 · tracked via the Priya Life Science India tracker

Sponsor

Institute of Liver and Biliary Sciences, India

Phase

Observational

Started

2025-12-07

Last updated

2025-12-31

Condition(s) studied

Hepatobiliary DiseasePancreas DiseaseBile Duct Diseases

Investigational drug(s) / intervention(s)

NO TREATMENT

NO TREATMENT: NO TREATMENT

Study summary

Hepatobiliary and Pancreatic surgery is associated with substantial risk of postoperative complications. Albumin is a negative acute phase protein. Its rapid decline may be due to degree of inflammation due to surgical procedures. The decline may due to multifactorial causes. Currently, contemporary data regarding the time to recovery of albumin, as a marker for early recovery of patient from surgical stress is sparse. Delta albumin is influenced by perioperative fluid administration and albumin supplementation. Delta albumin may not reflect the true surgical stress. Early post op albumin is a reflection of intraoperative events and not postoperative recovery or events and is unpredictable. Shorter recovery time of albumin is associated with less post op complications and hospital stay. Earlier recovery of albumin predicts lower morbidity and shorter hospital stay.

Eligibility

Sex

ALL

Min age

13 Years

Max age

80 Years

Healthy volunteers

Inclusion Criteria: 1. All patients undergoing major Hepato pancreatico Biliary surgeries. 2. Patients who are more than 12 years of age 3. Retrospective arm - Data from 2010 Exclusion Criteria: 1. Patients who refuse or are unable to give consent. 2. Patients with Nephrotic syndrome, Protein losing enteropathies, Inflammatory bowel 3. Disease, Chronic Liver Disease. 4. Emergency Surgeries

Primary outcome measure(s)

Time to recovery of serum albumin as a predictor of outcome in major hepatobiliary surgeries as measured by hospital stay. — 30 days
Time taken for unsupported albumin in Liver function test in a rising trend (g/dl)

Trial sites (1)

Facility	City	Region	Status
ILBS	New Delhi	National Capital Territory of Delhi	Recruiting

More Institute of Liver and Biliary Sciences, India trials in India

The Study of Association of Helicobacter Infections in Biliary Tract Cancers Recruiting

Standard Volume vs. High Volume Plasma Exchange in Pediatric Acute Liver Failure Recruiting

Goal Directed Ammonia Lowering Therapy in Hyperammonemic ACLF Patients With no Overt HE to Reduce Major Adverse Liver Related Outcomes (GOAL Trial) Starting soon

Effect of Perioperative Oral Rifaximin on Early Graft Dysfunction in Adult Living Donor Liver Transplant Recruiting

Compare the Efficacy and Safety of Dabigatran and Enoxaparin in Patients With Portal Vein Thrombosis With Cirrhosis Starting soon

Other trials for the same condition

A COMBINATION OF RECTAL INDOMETHACIN AND COLD WATER EXPOSURE OF THE AMPULLA AFTER ERCP IS SUPERIOR TO RECTAL INDOMETHACIN ALONE IN REDUCING THE INCIDENCE OF POST-ERCP PANCREATITIS -RCT Recruiting

UNITY-B A Prospective, Multicentric, Single-arm Study to Evaluate the Safety and Efficacy of the UNITY-B Biodegradable Balloon-Expandable Biliary Stent System in Subjects With Biliary Strictures Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07263061 on ClinicalTrials.gov ↗ ← All trials in India