Clinical trial register · India

Clinical Trials in Mumbai, 2026

Every study on the ClinicalTrials.gov registry that lists a site in India and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 1120 matching records held by the registry are in this view. Synced 07 Nov 2026, 03:16 UTC

1120

Studies in scope

all four open statuses

608

Recruiting now

open to new participants

218

Lead sponsors

across recruiting studies

Top sites

New Delhi 339 Mumbai 260 Hyderabad 233 Bangalore 199 Pune 186

Trials with a site in Mumbai

Status

Study

Lead sponsor

Phase

Enrol

Indian sites

Start

Not yet open

AMAZE 13: A Research Study Investigating How Well the Medicine Zenagamtide Helps People in Asia With Excess Body Weight Lose Weight

NCT07668401Obesity, Overweight

DrugZenagamtide

Novo Nordisk A/S

Phase 3

400

Surat, Vadodara, Hubbali, Kozhikode, Indore, Kohlapur, Kolhāpur, Mumbai

2027-01-07

Not yet open

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk

NCT07900633Obesity, Overweight, Cardiovascular Diseases, Diabetes Mellitus, Type 2

DrugEloralintide

Eli Lilly and Company

Phase 3

3,000

Belagavi, Guntur, Guwahati, Mumbai, Nagpur, Pune, Rishikesh, Surat

2026-12

Not yet open

A Study to Assess the Safety, and Tolerability of Nivolumab + Relatlimab Fixed-Dose Combination (FDC) In Unresectable or Metastatic Melanoma Participants In India

NCT07459543Unresectable Melanoma, Metastatic Melanoma

DrugsRelatlimab·Nivolumab

Bristol-Myers Squibb

Phase 4

Nashik, Mumbai, Navi Mumbai, Pune, Bhubaneswar, Chennai, Nagpur, New Delhi

2026-11-15

Not yet open

Tracheostomy Practice in Adult Intensive Care Units

NCT07769021Tracheostomy Patients, Tracheostomy Decannulation, Intensive Care (ICU)

Royal College of Surgeons, Ireland

Observational

2,500

Mumbai

2026-11-02

Not yet open

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease

NCT07838155Alzheimer Disease

DrugDonanemab

Eli Lilly and Company

Phase 4

Bangalore, Hyderabad, Kolkata, Mumbai, New Delhi, Tamil Nadu, Vellore

2026-11

Not yet open

Cefepime-Zidebactam Versus Ceftazidime-Avibactam With or Without Colistin for Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia

NCT07885891Hospital Acquired Bacterial Pneumonia (HABP), Ventilator Associated Bacterial Pneumonia (VABP)

DrugsWithout Colistin·Ceftazidime-avibactam

Wockhardt

Phase 3

324

Gurgaon, Mumbai, Pune, New Delhi, Pimpri-Chinchwad, Jaipur, Chengalpattu, Secunderabad

2026-10-28

Not yet open

The Primary Prevention of Intimate Partner Violence

NCT06811922Intimate Partner Violence

Emory University

Not applicable

1,700

Mumbai, Pune

2026-10

Not yet open

A Study Comparing Oral Ketamine With Oral Midazolam for the Treatment of Major Depressive Episodes

NCT07839338Major Depressive Episode

DrugsKetamine·Midazolam

Jawaharlal Institute of Postgraduate Medical Education & Research

Phase 3

220

Bangalore, Udupi, Mumbai, Bhubaneswar, Puducherry

2026-10

Recruiting

Torvutatug Samrotecan Plus Bevacizumab as First-line Maintenance in Non-Homologous Recombination Deficiency (Non-HRD) Positive Advanced Epithelial Ovarian Cancer

NCT07851025Epithelial Ovarian Cancer

DrugsTorvutatug samrotecan·Avastin·Bevacizumab

AstraZeneca

Phase 3

950

Ansārinagar, Bhubaneswar, Hyderabad, Mumbai, Nagpur, Nashik, New Delhi, Pune

2026-09-16

Not yet open

A Study of Chlorophyllin or Placebo With Standard Treatment for Late Radiation Induced Luminal Gastrointestinal Tract Bleeding

NCT07837713Radiation Proctitis, Gastrointestinal Hemorrhage, Radiation Injuries

DrugChlorophyllin, Sodium Copper Complex

Tata Memorial Centre

Phase 3

200

Mumbai

2026-09-15

Not yet open

A Study Testing if Patients With Advanced Prostate Cancer Who Are Responding Well to Combination Treatment Can Safely Reduce Their Medication to a Single Hormone Therapy, Compared to Continuing Their Current Drugs

NCT07838753Castration Sensitive Prostate Cancer, Metastatic Prostate Cancer

Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute

Phase 2

170

Mumbai

2026-09

Recruiting

Glioma Adaptive Radiotherapy With Development of an Artificial Intelligence Workflow

NCT06492486Diffuse Glioma, Glioblastoma, Adaptive Radiotherapy, Artificial Intelligence

Tata Memorial Centre

Phase 2

Mumbai

2026-07-27

Recruiting

A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan Fasting

NCT07613307Diabetes Mellitus, Type 2, Diabetes Melletus, Glucose Metabolism Disorders, Metabolic Disorders

DrugOrforglipron

Eli Lilly and Company

Phase 3

130

Agra, Hyderabad, Kanpur, Kolkata, Mumbai, Mysore, Nashik, Nellore

2026-07-15

Recruiting

A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes

NCT07668336Diabetes Mellitus, Type 2

DrugsDulaglutide·Orforglipron

Eli Lilly and Company

Phase 3

170

Ahmedabad, Aligarh, Bhubaneswar, Guntur, Mumbai, Nashik, New Delhi

2026-07-08

Recruiting

Phase 3 Study of LUM-201 in Children With Growth Hormone Deficiency

NCT06948214Growth Hormone Deficiency (GHD)

DrugLUM-201

Lumos Pharma

Phase 3

150

Mumbai, Nashik, Jaipur, Madurai, Chandigarh

2026-05-20

Not yet open

AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

NCT07400107Obesity, Overweight, Diabetes Mellitus, Type 2

DrugsNNC0487-0111·Semaglutide

Novo Nordisk A/S

Phase 3

1,000

Guntur, Surat, Vadodara, Bangalore, Bengaluru, Kochi, Indore, Mumbai

2026-05-20

Recruiting

AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

NCT07571109Obesity, Overweight, Obstructive Sleep Apnoea

DrugNNC0487-0111

Novo Nordisk A/S

Phase 3

300

Guntur, Vijayawada, Bengaluru, Kochi, Mumbai, Nagpur, New Delhi, Delhi

2026-05-05

Recruiting

AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

NCT07571005Obesity, Overweight, Obstructive Sleep Apnoea

DrugNNC0487-0111

Novo Nordisk A/S

Phase 3

300

Guntur, Vijayawada, Bengaluru, Kochi, Mumbai, Nagpur, Delhi, Bhubaneswar

2026-05-05

Recruiting

A Seamless Phase II/III, Observer-blind, to Evaluate Immunogenicity and Safety of Chikungunya Virus Vaccine in Healthy Subjects 12-65Years of Age.

NCT07555392Active Immunisation for Chikungunya Virus Infection

Bharat Biotech International Limited

Phase 2/3

1,000

Guwahati, Patna, Raipur, Mumbai, Rohtak, Bhubaneswar, Ajmer, Bikaner

2026-04-20

Recruiting

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

NCT07415044Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate, Ulcerative Colitis, Active Severe

DrugZotemtegrast

Eli Lilly and Company

Phase 2

1,431

Allahabād, Belagavi, Belgavi, Hyderabad, Jaipur, Kochi, Lucknow, Mumbai

2026-03-26

Recruiting

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

NCT07351045Obesity or Overweight

Hoffmann-La Roche

Phase 3

2,000

Ahmedabad, Trivandrum, Mumbai, Pune

2026-03-16

Recruiting

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

NCT07361497Non-small Cell Lung Cancer (NSCLC)

DrugsPumitamig·Durvalumab

Bristol-Myers Squibb

Phase 3

850

Eluru, Goraj, Pūlakkōd, Chhatrapati Sambhajinagar, Mumbai, Nagpur, Dwarka, New Delhi

2026-03-16

Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

NCT07221149Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma

DrugsPumitamig·Folfox·Nivolumab

Bristol-Myers Squibb

Phase 2/3

690

Nashik, Mumbai, Delhi, Puducherry, Pune

2026-03-13

Recruiting

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

NCT07361510Non-Small Cell Lung Cancer (NSCLC)

DrugsPumitamig·Pembrolizumab

Bristol-Myers Squibb

Phase 3

750

Visakhapatnam, Goraj, Mumbai, Nagpur, Dwarka, Hyderabad, Delhi, Pune

2026-03-12

Recruiting

Study to Assess the Safety and Effectiveness of Novel Radiopharmaceutical Terbium-161 DOTATATE in Metastatic Neuroendocrine Tumors

NCT07404176Neuroendocrine Neoplasms (Tumours), Neuroendocrine Tumors, Metastatic Neuroendocrine Tumors

Tata Memorial Hospital

Phase 2

Mumbai, Navi Mumbai

2026-03-01

Active, closed

Study to Assess the Efficacy of EMC-CAP-2025A on Age-Related Skin Parameters in Healthy Individuals

NCT07493850Facial Wrinkles, Skin Hydration, Skin Elasticity

Circul'Egg

Phase 2

Mumbai

2026-02-27

Recruiting

Asian Gynecological Brachytherapy Registry in Cervical Cancer

NCT07196033Stage IIIA Cervical Cancer FIGO 2018, Stage IIIB Cervical Cancer FIGO 2018, Stage IVA Cervical Cancer FIGO 2018, Stage IB Cervical Cancer FIGO 2018

Tata Memorial Hospital

Observational

1,000

Mumbai

2026-02-20

Recruiting

Self-administered Remote Neurological Examination Using Mobile Application in Patients With Brain Tumors

NCT07236840CNS Tumor, Artificial Intelligence (AI), Glioma, Digital Health

Tata Memorial Centre

Observational

600

Mumbai

2026-02-20

Not yet open

Affordable Made-in-India Microspheres for Liver Cancer Therapy

NCT07436988Hepatecellular Carcinoma

Post Graduate Institute of Medical Education and Research, Chandigarh

Phase 1

Chandigarh, Mumbai, Bhubaneswar, Puducherry, Delhi

2026-02-15

Recruiting

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

NCT07321886Obesity, Overweight

DrugEloralintide

Eli Lilly and Company

Phase 3

1,980

Guntur, Guwahati, Hyderabad, Mandya, Mumbai, Mysore, Nagpur, Nashik

2026-02-06

Recruiting

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

NCT07431281Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Esophageal Cancer

DrugsSonesitatug Vedotin·Zolbetuximab·Rilvegostomig·Leucovorin

AstraZeneca

Phase 3

2,130

Ahmedabad, Bhubaneswar, Hyderabad, Kolkata, Mohali, Mumbai, New Delhi, Varanasi

2026-02-03

Recruiting

Evenamide, a Glutamate Release Modulator, as Add-On to Standard of Care in Subjects With Documented Treatment-Resistant Schizophrenia

NCT07184619Treatment-resistant Schizophrenia

Newron Pharmaceuticals SPA

Phase 3

400

Vijayawada, Guwahati, Mumbai, Nagpur, Navi Mumbai, Madurai, Bībīnagar, Lucknow

2026-01-23

Recruiting

Efficacy and Safety of GL0034 in Overweight or Obese Adults With Type II Diabetes Mellitus

NCT07282743Type II Diabetes Mellitus

DrugGL0034

Sun Pharmaceutical Industries Limited

Phase 2

285

Guntur, Bangalore, Kozhikode, Trivandrum, Kolhāpur, Mumbai, Pune, New Delhi

2026-01-20

Recruiting

A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

NCT07063745Metastatic Non-small Cell Lung Cancer With MTAP Deletion

DrugsNavlimetostat·Nab-paclitaxel·Pemetrexed·Paclitaxel

Bristol-Myers Squibb

Phase 2/3

590

Bangalore, Bengaluru, Mumbai, Nashik, New Delhi, Varanasi, Hyderabad

2026-01-02

Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

NCT07221357Untreated, Unresectable, or Metastatic Colorectal Cancer

DrugsPumitamig·Folfox·Bevacizumab

Bristol-Myers Squibb

Phase 2/3

990

Nashik, Thiruvananthapuram, Mumbai, Delhi, Puducherry, Pune

2025-12-31

Recruiting

A Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male Participants Aged 1 to Less Than 12 Years With Hemophilia A or B

NCT07285460Hemophilia

DrugsAntithrombin·Clotting factor concentrates·Fitusiran

Sanofi

Phase 3

Bengaluru, Mumbai, Pune, Vellore

2025-12-18

Recruiting

A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

NCT07221253Biliary Tract Cancer

DrugsGemcitabine/Cisplatin·Rilvegostomig·Durvalumab

AstraZeneca

Phase 3

1,100

Delhi, Hyderabad, Kolhāpur, Kolkata, Mumbai, Nashik, Surat

2025-12-04

Recruiting

BIO-SHORT: Hypofractionated RT for Poor-Prognosis GBM

NCT07338539Glioma

Tata Memorial Centre

Not applicable

108

Mumbai

2025-11-06

Recruiting

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

NCT07100080Non-Small Cell Lung Cancer

DrugsIza-bren·Pemetrexed·Cisplatin·Carboplatin

Bristol-Myers Squibb

Phase 2/3

500

Ahmedabad, Gurugram, Bengaluru, Mumbai, Nagpur, New Delhi, Howrah

2025-11-05

Recruiting

Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

NCT07291037Non-small Cell Lung Cancer (NSCLC)

DrugsDato-DXd·Docetaxel

AstraZeneca

Phase 3

400

Bangalore, Kolkata, Mumbai, Nashik, New Delhi

2025-10-31

Recruiting

Systemic and Tumor Immune Response During Pelvic (Chemo)Radiation and/or Brachytherapy for Cervical Cancer

NCT06804135Cervical Carcinoma

Tata Memorial Hospital

Observational

110

Mumbai

2025-10-25

Active, closed

A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)

NCT07076121Pancreatic Ductal Adenocarcinoma

DrugsNavlimetostat·Abraxane·Nab-paclitaxel·Gemcitabine

Bristol-Myers Squibb

Phase 2/3

470

Kochi, Mumbai, New Delhi, Bhubaneswar, Hyderabad, Varanasi, Kolkata

2025-10-23

Recruiting

A Study of Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

NCT07209761Rifampicin-Resistant Pulmonary Tuberculosis, Multidrug-Resistant Pulmonary Tuberculosis

DrugsPretomanid·Bedaquiline·Linezolid·Moxifloxacin

Otsuka Pharmaceutical Development & Commercialization, Inc.

Phase 3

532

Mumbai, New Delhi, Chennai

2025-10-16

Recruiting

Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes

NCT07102628Acute Coronary Syndrome

DrugInclisiran

Novartis Pharmaceuticals

Phase 3

300

Belagavi, Mumbai, Nashik, Bikaner

2025-10-03

Recruiting

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

NCT06989437Cachexia, Metastatic Pancreatic Ductal Adenocarcinoma

DrugPonsegromab

Pfizer

Phase 2/3

982

Mumbai, New Delhi, Jaipur, Kolkata

2025-10-03

Recruiting

Phase II Trial of Immunonutrition in Hepatectomy

NCT07395635Hepatocellular Carcinoma, ASA I-III Patients

Tata Memorial Centre

Not applicable

100

Mumbai

2025-10-03

Recruiting

Data Collection Using Eko Devices in a Clinical Setting

NCT07270744Lung Diseases

Eko Devices, Inc.

Observational

200

Mumbai

2025-10-01

Recruiting

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

NCT07144280Non-small Cell Carcinoma, Non-Small Cell Lung Cancer Metastatic, Non-Small Cell Lung Carcinoma

DrugsPF-08046054·Docetaxel

Pfizer

Phase 3

680

Mumbai, Pune, New Delhi, Kolkata, Delhi, Kerala

2025-09-29

Recruiting

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

NCT06926868Breast Neoplasms

DrugsIza-bren·Nab-paclitaxel·Capecitabine·Gemcitabine

Bristol-Myers Squibb

Phase 2/3

600

Mumbai, Nagpur, New Delhi, Chennai, Hyderabad, Varanasi

2025-09-11

Recruiting

A Research Study to See How Safe is Eptacog Alfa When Used to Stop Heavy Bleeding in Women After Giving Birth in India

NCT07157423Severe Postpartum Haemorrhage

DrugRecombinant factor VIIa

Novo Nordisk A/S

Phase 4

Belagavi, Mysore, Kozhikode, Mumbai, New Delhi, Jaipur, Udaipur, Hyderabad

2025-08-26

Recruiting

A Study of Guselkumab Administered Subcutaneously in Treatment of Indian Participants With Psoriatic Arthritis (PsA)

NCT07141004Arthritis, Psoriatic

DrugsTremfya·Guselkumab

Johnson & Johnson Private Limited

Phase 4

100

Ahmedabad, Chandigarh, Chennai, Gorakhpur, Hyderabad, Mumbai, New Delhi, Patna

2025-08-12

Recruiting

A Study to Test the Safety and Tolerability of SBO-154 in Patients With Advanced Solid Tumors.

NCT07042100Advanced Solid Tumors

DrugPumitamig

Sun Pharma Advanced Research Company Limited

Phase 1

177

Rohtak, Ernākulam, Mumbai, Pune, Delhi, Bikaner, Udaipur

2025-08-12

Recruiting

Intensity Modulated PrOton Therapy in Pediatric BRain Tumors (IMPORT)

NCT07338526Brain Tumor, Pediatric

Tata Memorial Centre

Not applicable

Mumbai

2025-08-07

Active, closed

Parent Study: A Study to Assess Efficacy and Safety of Baxdrostat in Participants With Primary Aldosteronism Sub-study: A Follow-up Substudy After Completion of the BaxPA Main Study.

NCT07007793Primary Hyperaldosteronism

DrugBaxdrostat

AstraZeneca

Phase 3

212

Belagavi, Delhi, Hyderabad, Kolkata, Mumbai

2025-08-07

Recruiting

A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation

NCT06952803Prostate Cancer

DrugsPrednisolone/prednisone·Saruparib·Abiraterone

AstraZeneca

Phase 3

700

Ansārinagar, Babgalore, Calicut, Delhi, Hyderabad, Kannur, Kanpur, Mumbai

2025-08-06

Recruiting

A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

NCT07062965Breast Cancer

DrugsPrifetrastat·Exemestane·Everolimus·Fulvestrant

Pfizer

Phase 3

400

Surat, Gurugram, Bengaluru, Mumbai, Nashik, Pune, Thane, Bhubaneswar

2025-08-05

Recruiting

Detection of Reduced Left Ventricular Ejection Fraction With Three-Lead ECG Using Artificial Intelligence

NCT07270692Low Ejection Fraction

Eko Devices, Inc.

Observational

500

Mumbai

2025-08-01

Active, closed

Effects of a Financial Literacy and Gender-Transformative Couples Intervention on Parenting Practices in India

NCT07651670Parenting Practices, Intimate Partner Violence (IPV), Mental Health, Empowerment

Shruti Shukla

Not applicable

4,552

Visakhapatnam, Mumbai, Jaipur, Noida

2025-07-29

Active, closed

Strengthening Relationships and Mental Health Through a Couples-Based Economic Empowerment Intervention

NCT07108049Mental Health, Empathy, Relation, Interpersonal

Technical University of Munich

Not applicable

4,552

Mumbai, Noida

2025-07-29

Recruiting

A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)

NCT06911502Follicular Lymphoma

DrugsPrednisone/Prednisolone·Golcadomide·Bendamustine·Vincristine

Celgene

Phase 3

400

Bengaluru, Mumbai, New Delhi, Hyderabad

2025-07-28

Recruiting

Study to Assess Adverse Events and Change in Disease Activity of Oral Venetoclax in Combination With Subcutaneous (SC) or Intravenous (IV) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Standard Induction Therapy in India

NCT07044687Acute Myeloid Leukemia

DrugsAzacitidine·Venetoclax

AbbVie

Phase 4

100

Gurgaon, Bengaluru, Thiruvananthapuram, Mumbai, Pune, New Delhi, Bhubaneswar, Chennai

2025-07-24

Recruiting

This is a Study to Learn About How the Combination of the Study Medicines Sigvotatug Vedotin Plus Pembrolizumab Works in People With Non-small Cell Lung Cancer With High Levels of PD-L1.

NCT06758401Non-Small Cell Lung Cancer, Carcinoma, Non-Small-Cell Lung, Carcinoma, Non-Small-Cell Lung (NSCLC)

DrugsSigvotatug vedotin·Pembrolizumab

Pfizer

Phase 3

714

Bengaluru, Mumbai, Pune, Thane, New Delhi, Hyderabad

2025-07-23

Recruiting

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

NCT06855277Prostate Cancer

DrugsAAA817·ARPI

Novartis Pharmaceuticals

Phase 3

940

Gurgaon, Bengaluru, Mumbai

2025-07-01

Recruiting

Proton Versus Photon Radiotherapy in Adults With Primary Brain Tumors

NCT06831461Primary Brain Tumors, Diffuse Glioma, Meningioma, Pituitary Adenoma

Tata Memorial Centre

Not applicable

156

Mumbai

2025-07-01

Recruiting

A Research Study Comparing CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Reduced/Mildly Reduced Ejection Fraction and Left Ventricular Hypertrophy

NCT06979375Heart Failure

DrugCDR132L

Novo Nordisk A/S

Phase 2

200

Vadodara, Kochi, Mumbai, Nagpur, New Delhi, New Dehli, Ludhiana, Dehradun

2025-06-30

Recruiting

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

NCT07082738Chronic Obstructive Pulmonary Disease (COPD)

AstraZeneca

Phase 2

987

Belagavi, Coimbatore, Dehradun, Delhi, Dwārka, Hyderabad, Kochi, Mumbai

2025-06-27

Recruiting

A Safety Study of Enfortumab Vedotin in Indian Adults With Urothelial Cancer

NCT06862219Metastatic Urothelial Carcinoma

DrugEnfortumab Vedotin

Astellas Pharma Global Development, Inc.

Phase 4

100

Patna, Kochi, Mumbai, New Delhi, Dumas, Vellore, Varanasi, Kolkata

2025-06-21

Recruiting

Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates

NCT06377397Sepsis, PROM, Preterm (Pregnancy), Early-Onset Neonatal Sepsis, Preterm Premature Rupture of Membrane

Indian Council of Medical Research

Phase 3

1,500

Chandigarh, Rohtak, Bengaluru, Chhatrapati Sambhajinagar, Mumbai, New Delhi, Chennai, Lucknow

2025-06-07

Active, closed

C-Forward: Efficacy and Safety of BEM/RZR vs SOF/VEL in Subjects With Chronic HCV

NCT07037277HEPATITIS C VIRUS CHRONIC INFECTION, Hepatitis C, Chronic, Hepatitis C Virus Infection, Hepatitis C

DrugSofosbuvir-Velpatasvir

Atea Pharmaceuticals, Inc.

Phase 3

880

Hyderabad, Patna, Rajkot, Surat, Shimla, Belagavi, Kochi, Mumbai

2025-06-02

Active, closed

A Study to Assess Safety of Teclistamab in Indian Participants With Relapsed and Refractory Multiple Myeloma

NCT07030517Multiple Myeloma

DrugTeclistamab

Johnson & Johnson Private Limited

Phase 4

Bangalore, Bengaluru, Chandigarh, Jaipur, Kolkata, Mumbai, Nagpur, New Delhi

2025-05-22

Recruiting

A Study to Learn About How Changing Therapy From Emicizumab to Marstacimab Affects People With the Severe Hemophilia A.

NCT06703606Severe Hemophilia A

DrugMarstacimab

Pfizer

Phase 1

Surat, Mumbai

2025-05-13

Recruiting

Late Radiation Toxicities in Cervical and Endometrial Cancer: A Postoperative IMRT/Brachytherapy Study

NCT07435623Endometrial Cancer, Cervix Cancer

Tata Memorial Hospital

Observational

300

Mumbai

2025-05-10

Recruiting

A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)

NCT06935357Immunoglobulin A Nephropathy (IgAN)

DrugFelzartamab

Biogen

Phase 3

454

Hyderabad, Raipur, Ahmedabad, Nadiād, Bangalore, Kozhikode, Trivandrum, Mumbai

2025-05-08

Recruiting

Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

NCT06921785Hepatocellular Carcinoma

DrugsRilvegostomig·Tremelimumab·Atezolizumab·Bevacizumab

AstraZeneca

Phase 3

1,220

Ahmedabad, Bangalore, Binnāguri, Dehradun, Delhi, Hyderabad, Mumbai, Nashik

2025-05-06

Recruiting

A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

NCT06499285Myelodysplastic Syndromes

DrugElritercept

Takeda

Phase 3

225

Ahmedabad, Ernākulam, Mumbai, New Delhi, Ludhiana, Vellore, Ghaziabad, Kolkata

2025-05-06

Recruiting

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

NCT06875310Carcinoma, Non-Small-Cell Lung

DrugsAdagrasib·Pemetrexed·Keytruda·Cisplatin

Mirati Therapeutics Inc.

Phase 3

630

Visakhapatnam, Ahmedabad, Thiruvananthapuram, Mumbai, New Delhi, Bhubaneswar, Madurai, Hyderabad

2025-04-24

Recruiting

Sentinel Node Biopsy Versus Limited Elective Neck Dissection in Early Cancers of Oral Cavity NoDe Negative

NCT05774483Mouth Neoplasms, Oral Cancers, Oral Squamous Cell Carcinoma (OSCC), Oral Squamous Cell Carcinomas

Tata Memorial Hospital

Not applicable

508

Mumbai, Navi Mumbai, Varanasi

2025-04-16

Recruiting

Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer

NCT06890598Carcinoma, Non-Small-Cell Lung

DrugsOlomorasib·Durvalumab·Pembrolizumab

Eli Lilly and Company

Phase 3

700

Ahmedabad, Chennai, Chhatrapati Sambhajinagar, Mumbai, Namakkal, Patna, Pune, Thalassery

2025-03-27

Recruiting

Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

NCT06819007Ovarian Cancer

DrugsTrastuzumab deruxtecan·Bevacizumab

Daiichi Sankyo

Phase 3

582

Ahmedabad, Delhi, Kolkata, Mumbai, Nagpur, Nashik, Pune, Vadodara

2025-03-19

Recruiting

IMRT Versus IMPT With Concurrent Chemotherapy for Locally Advanced Anal Canal Cancer

NCT06630793Malignant Neoplasm of Anal Canal

Tata Memorial Centre

Not applicable

108

Mumbai

2025-03-18

Recruiting

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Newly Diagnosed Active Crohn Disease

NCT06890650Crohn Disease

All India Institute of Medical Sciences

Not applicable

168

Kochi, Mumbai, New Delhi, Ludhiana, Chandigarh, Varanasi

2025-03-15

Recruiting

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Newly Diagnosed Active Ulcerative Colitis

NCT06895252Ulcerative Colitis (UC)

All India Institute of Medical Sciences

Not applicable

220

Kochi, Mumbai, New Delhi, Ludhiana, Chandigarh, Varanasi

2025-03-15

Recruiting

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Ulcerative Colitis on Advanced Therapies

NCT06906445Ulcerative Colitis

All India Institute of Medical Sciences

Not applicable

220

Kochi, Mumbai, New Delhi, Ludhiana, Chandigarh, Varanasi

2025-03-15

Recruiting

A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Crohn Disease on Advanced Therapies

NCT06890637Crohns Disease

All India Institute of Medical Sciences

Not applicable

168

Kochi, Mumbai, New Delhi, Ludhiana, Varanasi, Chandigarh

2025-03-15

Recruiting

A Study to Learn About the Study Medicine Called Rimegepant in Women When Used for Intermittent Prevention of Menstrual Migraine

NCT06641466Menstrual Migraine

DrugRimegepant

Pfizer

Phase 3

723

Guntur, Ahmedabad, Mangaluru, Mumbai, Nagpur, Nashik, Ajmer, Lucknow

2025-03-11

Recruiting

A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

NCT06742723Chronic Kidney Disease and Hypertension

DrugBaxdrostat/dapagliflozin

AstraZeneca

Phase 3

5,000

Bangalore, Belagavi, Hyderabad, Kolkata, Madurai, Mumbai, New Delhi, Pune

2025-03-03

Recruiting

A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer

NCT06764875HER2-positive Gastric Cancer, Gastroesophageal Junction Adenocarcinoma

DrugsRilvegostomig·Trastuzumab deruxtecan·Trastuzumab·Adrucil

AstraZeneca

Phase 3

840

Ansārinagar, Bangalore, Delhi, Hyderabad, Kolkata, Mumbai, Varanasi

2025-03-01

Recruiting

Effects of Advanced Trauma Life Support® on Adult Trauma Patient Outcomes

NCT06321419Wounds and Injuries

Karolinska Institutet

Not applicable

4,320

Dibrugarh, Mumbai, New Delhi, Ludhiana, Dehradun, Kolkata, Chandigarh

2025-02-27

Active, closed

A Study to Evaluate the Efficacy and Safety of JNJ-77242113 (Icotrokinra) in Biologic-naïve Participants With Active Psoriatic Arthritis

NCT06878404Arthritis, Psoriatic

DrugIcotrokinra

Janssen Research & Development, LLC

Phase 3

552

Ahmedabad, Bhubaneswar, Hyderabad, Kolkata, Mumbai, Mysuru, New Delhi, Noida

2025-02-21

Recruiting

Reduced Length of ADT and ARTA With XRT in High-Risk Prostate Cancer (RELAX): A Randomised Trial

NCT06818682Prostate Carcinoma

Tata Memorial Centre

Phase 2

206

Mumbai

2025-02-17

Recruiting

Which of the Commonly Available and Approved Drugs in Addition to Standard of Care Can Significantly Improve the Slope of Estimated Glomerular Filtration Rate at Two Years When Compared to Standard of Care Alone in South-Asian Kidney Biopsy-proven Adult (≥18 Years) Primary IgA Nephropathy?

NCT06676384IgA Nephropathy, Renal Insufficiency, Chronic, IgA Vasculitis, IGA Glomerulonephritis

Christian Medical College, Vellore, India

Phase 4

585

Nadiād, Mysuru, Udupi, Mumbai, Delhi, Bhubaneswar, Puducherry, Chennai

2025-02-15

Recruiting

Systemic Biomarkers to Predict Radiation-Induced Neurocognitive Decline

NCT06779487Brain Tumors, Medulloblastoma, Glioma, Ependymoma

Tata Memorial Centre

Observational

200

Mumbai

2025-02-11

Recruiting

Tracing Brain Tumors Through Deep Time

NCT06381531Brain Tumor, Oncology

Tata Memorial Centre

Observational

10,000

Mumbai

2025-01-10

Recruiting

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

NCT06609226Sickle Cell Disease, Thalassemia

Novo Nordisk A/S

Phase 3

480

Raipur, Mumbai, Bangalore, Gujarat, Maharashtra, New Delhi

2025-01-10

Active, closed

Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease

NCT06760637Breast Cancer

DrugsAtirmociclib·Ribociclib·Abemaciclib·Palbociclib

Pfizer

Phase 3

1,035

Surat, Gurugram, Bangalore, Mumbai, Nashik, Pune, Thane, New Delhi

2025-01-06

Recruiting

FAPi PET in Pancreatic Ductal Adenocarcinoma

NCT07342231Pancreatic Cancer, Adenocarcinoma Pancreas

Tata Memorial Hospital

Observational

Mumbai

2025-01-04

Recruiting

Craniospinal Irradiation in Histone AlteRed Midline Glioma

NCT06720727Glioma

Tata Memorial Centre

Not applicable

Mumbai

2025-01-03

Active, closed

Phase 4 Study to Assess the Safety of Trastuzumab Deruxtecan, in Indian Patients

NCT06429761BREAST CANCER

DrugTrastuzumab deruxtecan

AstraZeneca

Phase 4

100

Bangalore, Delhi, Kochi, Mumbai, New Delhi, Pune, Varanasi

2025-01-02

Recruiting

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

NCT06750094Colorectal Neoplasms

DrugsLeucovorin calcium/Levoleucovorin·Amivantamab·Erbitux·Avastin

Janssen Research & Development, LLC

Phase 3

700

Delhi, Hyderabad, Kolkata, Mumbai, New Delhi, Pune, Varanasi, Vellore

2024-12-12

Active, closed

Impact of Molecular Pathological And Clinical Features for Adjuvant Treatment Selection in Endometrial Cancer: Asian Registry

NCT07354087Endometrial Cancer

Tata Memorial Hospital

Observational

300

Mumbai, Navi Mumbai

2024-11-28

Active, closed

A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUCIA) Primary Efficacy Will be Determined at Week 56

NCT06683742Wet Age Related Macular Degeneration, wAMD

DrugsEYP-1901·Aflibercept

EyePoint Pharmaceuticals, Inc.

Phase 3

400

Ahmedabad, Kolkata, Miraj, Mumbai, Varanasi

2024-11-27

Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

NCT06627647Non-squamous Non-small Cell Lung Cancer

DrugsRilvegostomig·Pemetrexed·Keytruda·Cisplatin

AstraZeneca

Phase 3

1,160

Calicut, Delhi, Gūrgaon, Kolkata, Madurai, Mumbai, Nashik, New Delhi

2024-11-27

Recruiting

A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

NCT06692738Non-small Cell Lung Cancer

DrugsRilvegostomig·Nab-paclitaxel·Keytruda·Paclitaxel

AstraZeneca

Phase 3

1,160

Calicut, Delhi, Gūrgaon, Kolkata, Madurai, Mumbai, Nagpur, Nashik

2024-11-18

Recruiting

An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and Older

NCT06666491Malaria, Vivax

DrugsChloroquine·Primaquine·Tafenoquine

GlaxoSmithKline

Phase 3

324

Ahmedabad, Bikaner, Kolkata, Mumbai, Surat

2024-11-13

Recruiting

Asian Watch-and-Wait Database (AWWD)

NCT06631443Rectal Adenocarcinoma, Rectal Cancer

Tata Memorial Centre

Observational

337

Mumbai

2024-10-22

Recruiting

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

NCT06662786Colorectal Neoplasms

DrugsLeucovorin calcium/Levoleucovorin·Amivantamab·Erbitux·Irinotecan

Janssen Research & Development, LLC

Phase 3

1,000

Delhi, Kolkata, Mumbai, Pune, Varanasi

2024-10-18

Active, closed

A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

NCT06470048Diffuse Cutaneous Systemic Sclerosis

DrugIanalumab

Novartis Pharmaceuticals

Phase 2

201

Kochi, Mumbai, New Delhi, Jaipur

2024-10-09

Recruiting

A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

NCT06561386Non-small Cell Lung Cancer

DrugsRelatlimab·Pemetrexed·Nivolumab·Cisplatin

Bristol-Myers Squibb

Phase 3

1,000

Badsa, Bengaluru, Thiruvananthapuram, Mumbai, New Delhi, Secunderabad, Varanasi, Howrah

2024-10-07

Recruiting

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

NCT06528314NASH - Nonalcoholic Steatohepatitis, MASH - Metabolic Dysfunction-Associated Steatohepatitis

DrugEfruxifermin

Akero Therapeutics, Inc

Phase 3

2,150

Hyderabad, Surat, Vadodara, Mysore, Thiruvananthapuram, Mumbai, Nagpur, Pune

2024-10-04

Active, closed

A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

NCT06417814Metastatic Non-small Cell Lung Cancer

DrugsTagrisso·Dato-DXd·Osimertinib·Pemetrexed

AstraZeneca

Phase 3

768

Hyderabad, Kolhāpur, Mumbai, Namakkal, Pune, Ranchi, Thane, Varanasi

2024-10-04

Active, closed

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

NCT06421636Non-Transfusion Dependent Beta-Thalassemia (NTDT)

Regeneron Pharmaceuticals

Phase 2

Ahmedabad, Surat, Kochi, Mumbai, New Delhi, Jaipur

2024-09-30

Active, closed

A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast

NCT06238622Idiopathic Pulmonary Fibrosis, Progressive Pulmonary Fibrosis

DrugNerandomilast

Boehringer Ingelheim

Phase 3

1,666

Mumbai

2024-09-26

Recruiting

Prospective Evaluation of 68Ga-FAPI PET in Biliary Cancers

NCT07337850Gall Bladder Cancer, Intrahepatic Cholangiocarcinoma (Icc)

Tata Memorial Centre

Observational

Mumbai

2024-09-25

Recruiting

First in Human Multicenter Open Name Dose-increase, Consolidation Method to Study Safety Drug-level in Blood & Drug Metabolism Clinical Activity of Oral JBI-778 in Lung Cancer Patients With, Without Brain Metastasis IDH Mutated WHO Grade 3,4 Recurrent Glioma, Salivary Glands Tumor

NCT07755397NSCLC Patients With EGFR Activating Mutation, Adenoid Cystic Carcinoma Metastatic, Adenoid Cystic Carcinoma of the Head and Neck

Jubilant Therapeutics India Limited

Phase 1

Surat, Bangalore, Mumbai, Nashik, Thane, New Delhi

2024-08-26

By invitation

Efficacy and Safety of Picroliv in Patients With Non-Alcoholic Fatty Liver Disease

NCT07452744Non Alcholic Fatty Liver Disease

Bioagile Therapeutics Pvt. Ltd.

Not applicable

170

Chandigarh, Panjagutta, Chowk, Mumbai, Delhi, Vasant Kunj

2024-08-13

Recruiting

Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract Cancer

NCT06467357Biliary Tract Cancer

DrugsRilvegostomig·Trastuzumab deruxtecan·Durvalumab·Gemcitabine

AstraZeneca

Phase 3

620

Dehradun, Delhi, Kanpur, Kolkata, Mumbai, Vadodara, Varanasi

2024-08-12

Recruiting

Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer

NCT06380751Advanced Breast Cancer

DrugsSaruparib·Camizestrant·Exemestane·Anastrozole

AstraZeneca

Phase 3

788

Delhi, Kolkata, Lucknow, Mumbai, Mysuru, Nagpur, Nashik, New Delhi

2024-08-01

By invitation

Long-term Safety and Tolerability of BHV-7000

NCT06443463Focal Epilepsy

DrugOpakalim

Biohaven Therapeutics Ltd.

Phase 2

660

Hyderabad, Mangalore, Mumbai, Nagpur, New Delhi

2024-07-30

Recruiting

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

NCT06282575Biliary Tract Cancer

DrugsZanidatamab·Durvalumab·Gemcitabine·Cisplatin

Jazz Pharmaceuticals

Phase 3

286

Belagavi, Mumbai, Nashik, Hyderabad, Varanasi, New Delhi

2024-07-19

Recruiting

Fibrosis Lessens After Metabolic Surgery

NCT06374875Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD), Non-Alcoholic Fatty Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis (MASH), Liver Fibrosis

The Cleveland Clinic

Phase 4

120

Indore, Mumbai

2024-07-11

Recruiting

Short Versus Long-term Levetiracetam in Brain Tumors

NCT06442748Seizures, Brain Tumors, Antiepileptics, Levetiracetam

DrugLevetiracetam

Tata Memorial Centre

Phase 3

604

Udupi, Mumbai

2024-07-04

Active, closed

Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma

NCT06356129Large B-cell Lymphoma

DrugsGolcadomide·Vincristine·Doxorubicin·Prednisone

Celgene

Phase 3

850

Belagavi, Kochi, Mumbai, New Delhi, Howrah, New Town

2024-06-19

Active, closed

Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)

NCT06305754Non-small Cell Lung Cancer (NSCLC)

DrugsSteroid mouthwash (dexamethasone·Acetaminophen·Sacituzumab tirumotecan·Pemetrexed

Merck Sharp & Dohme LLC

Phase 3

550

Gurugram, Mumbai, New Delhi

2024-06-11

Recruiting

A Study of Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

NCT06345729Non-small Cell Lung Cancer

DrugsCalderasib·Keytruda·Pembrolizumab

Merck Sharp & Dohme LLC

Phase 3

348

Mumbai, New Delhi

2024-05-24

Recruiting

Postoperative Radiotherapy in Breast Cancer- Concurrent or Sequential With Chemotherapy

NCT06926543Invasive Breast Cancer, Stage III Breast Cancer, Stage IIB Breast Cancer

Dr. Tabassum Wadasadawala

Phase 3

858

Vishkhapatnam, Mumbai, New Chandigarh, Sangrur, Varanasi

2024-05-14

Active, closed

Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

NCT06309966Focal Epilepsy

DrugOpakalim

Biohaven Therapeutics Ltd.

Phase 2/3

390

Hyderabad, Mangalore, Mumbai, Nagpur, New Delhi

2024-05-13

Active, closed

Endothelin Receptor Antagonism With Ambrisentan to Treat Hepatorenal Syndrome

NCT06256432Hepatorenal Syndrome, Liver Cirrhosis, Acute Kidney Injury, Ascites Hepatic

DrugsAmbrisentan·Terlipressin

Noorik Biopharmaceuticals AG

Phase 2

Bangalore, Mumbai, New Delhi, Hyderabad, Kanpur, Lucknow

2024-04-17

Recruiting

A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)

NCT06312176Breast Neoplasms

DrugsLiposomal doxorubicin·Abraxane·Xeloda·Sacituzumab tirumotecan

Merck Sharp & Dohme LLC

Phase 3

1,200

Mumbai, New Delhi

2024-04-14

Recruiting

Integrated Molecular and Clinical Profiling to Improve Disease Characterization and Outcome Prediction in Nodal Marginal Zone Lymphoma

NCT05700149Nodal Marginal Zone Lymphoma

International Extranodal Lymphoma Study Group (IELSG)

Observational

300

Mumbai

2024-04-11

Recruiting

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

NCT06256588Neoplasms, Head and Neck

DrugDostarlimab

GlaxoSmithKline

Phase 3

864

Mumbai, Pune, Bengaluru, Bhubaneswar, Gūrgaon, Hyderabad, Nashik, Nehru Nagar Belagavi Karnataka 590010

2024-03-21

Active, closed

A Study to Compare the Efficacy, Safety, Pharmacokinetics, and Immunogenicity Between SB27 and Keytruda in Subjects With Metastatic Non-squamous Non-small Cell Lung Cancer

NCT06348199Non-small Cell Lung Cancer Stage IV

DrugsKeytruda·Pembrolizumab

Samsung Bioepis Co., Ltd.

Phase 3

555

Bangalore, Bhubaneswar, Erandwane, Hyderabad, Jaipur, Mumbai, Sūrat, Udaipur

2024-03-12

Recruiting

Radiation Therapy in Unresectable Gall Bladder Cancer

NCT06214572Gall Bladder Cancer

DrugsDurvalumab·Nab-paclitaxel·Oxaliplatin·Cisplatin

Tata Memorial Centre

Phase 2/3

249

Mumbai

2024-03-07

Active, closed

AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

NCT06346392Gastric Cancer, Gastroesophageal Junction Cancer

DrugsSonesitatug Vedotin·Ramucirumab·Trifluridine/Tipiracil·Apatinib

AstraZeneca

Phase 3

594

Ahmedabad, Hyderabad, Mumbai, New Delhi

2024-03-04

Recruiting

Efficacy and Safety of Tenalisib in Patients With Metastatic Triple Negative Breast Cancer (TNBC)

NCT06189209Triple Negative Breast Cancer (TNBC)

Rhizen Pharmaceuticals SA

Phase 2

Vijayawada, Bangalore, Mumbai, Pune, Madurai, Hyderabad, Kolkata

2024-03-04

Active, closed

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

NCT05827081Early Breast Cancer

DrugsLeuprolide·Goserelin·Exemestane·Ribociclib

Novartis Pharmaceuticals

Phase 3

1,466

Hyderabad, Bangalore, Mumbai, Pune, New Delhi, Bhubaneswar, Chennai, Kolkata

2024-02-28

Recruiting

Evaluation of Memantine in the Preservation of Memory and Neurocognition Following CSI

NCT06275035Neurocognitive Dysfunction

DrugMemantine

Tata Memorial Centre

Phase 3

101

Mumbai

2024-02-22

Recruiting

A Study to Assess the Efficacy, Safety and Pharmacokinetics of EYU688 in Patients With Dengue Fever

NCT06006559Dengue

Novartis Pharmaceuticals

Phase 2

108

Belagavi, Mumbai, Pune, Jaipur, Chennai

2024-02-20

Recruiting

Spatial and Temporal Characterization of Gliomas Using Radiomic Analysis

NCT06036381Glioma

Tata Memorial Centre

Observational

1,000

Mumbai

2024-02-15

Recruiting

International obServational sTudy on AiRway manaGement in operAting Room and Non-operaTing Room anaEsthesia

NCT05759299Airway Complication of Anesthesia

University of Turin, Italy

Observational

10,500

Mumbai

2024-01-15

Active, closed

A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer)

NCT06065748Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer

DrugsGiredestrant·Ribociclib·Abemaciclib·Palbociclib

Hoffmann-La Roche

Phase 3

1,050

Banglore, Kozhikode, Trivandrum, Mumbai, Pune, Thane

2023-12-11

Active, closed

ARCHERY - Artificial Intelligence Based Radiotherapy Treatment Planning for Cervical, Head and Neck and Prostate Cancer

NCT05653063Cancer of Prostate, Cancer Head Neck, Cancer Cervix

University College, London

Observational

1,029

Kolkata, Mumbai

2023-12-07

Active, closed

Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)

NCT06109779Biliary Tract Cancer

DrugsGemcitabine/Cisplatin·Rilvegostomig·Teysuno·Capecitabine

AstraZeneca

Phase 3

760

Delhi, Kolkata, Mumbai, Mysuru, New Delhi, Varanasi

2023-12-04

Recruiting

POEM-F for Achalasia International Study

NCT06042127Achalasia

Chinese University of Hong Kong

Not applicable

Chandigarh, Hyderabad, Mumbai, Pune

2023-12-01

Recruiting

A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

NCT06215716NASH With Fibrosis, MASH With Fibrosis

DrugEfruxifermin

Akero Therapeutics, Inc

Phase 3

1,650

Surat, Vadodara, Mysore, Thiruvananthapuram, Dahegaon, Mumbai, Nagpur, Pune

2023-12-01

Recruiting

A Study of Chlorophyllin for the Management of Brain Radio-necrosis in Patients With Diffuse Glioma

NCT06016452Diffuse Glioma, Radionecrosis of Brain, High Grade Glioma, Glioblastoma Multiforme

DrugChlorophyllin

Tata Memorial Centre

Phase 2

118

Mumbai

2023-11-13

Active, closed

A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

NCT06161571NASH/MASH, NAFLD/MASLD

DrugEfruxifermin

Akero Therapeutics, Inc

Phase 3

700

Surat, Vadodara, Thiruvananthapuram, Dahegaon, Mumbai, Nagpur, Pune, New Delhi

2023-11-10

Active, closed

Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)

NCT05925803Systemic Sclerosis, Scleroderma

AstraZeneca

Phase 3

314

Ahmedabad, Delhi, Gurugram, Hyderabad, Kolkata, Mumbai, Mysuru, New Delhi

2023-11-08

Active, closed

An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)

NCT05952557Breast Cancer, Early Breast Cancer

DrugsCamizestrant·Tamoxifen·Exemestane·Anastrozole

AstraZeneca

Phase 3

5,511

Ansārinagar, Bangalore, Dehradun, Delhi, Kolkata, Kozhikode, Mumbai, Mysuru

2023-10-05

Recruiting

Artificial Intelligence in CNS Radiation Oncology

NCT06036394CNS Tumor

Tata Memorial Centre

Observational

6,000

Mumbai

2023-09-13

Recruiting

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

NCT05894239Metastatic Breast Cancer

DrugsPhesgo·Inavolisib

Hoffmann-La Roche

Phase 3

230

Ahmedabad, Surat, Gurugram, Mumbai, Nagpur, NEW Delhi Delhi, Kolkata

2023-09-08

Recruiting

Cervical Cancer Oligo States (Recurrence, Metastasis) Multicentre Outcomes Study.

NCT07400809Chemotherapy, Treatment Compliance, Radiotherapy, Cervix Cancer

Tata Memorial Hospital

Observational

350

Mumbai

2023-08-23

Recruiting

Trastuzumab Plus Chemotherapy vs Chemotherapy Alone in First-line HER2 Positive Advanced Biliary Tract Cancer Patients

NCT07062263Biliary Tract Cancer, HER2-positive Cancer, Advanced Cancer, Unresectable Biliary Tract Carcinoma

DrugTrastuzumab

Tata Memorial Centre

Phase 3

220

Muzaffarpur, Mumbai, Bhubaneswar, Mūllānpur, Varanasi, Delhi

2023-07-21

Active, closed

SCRT in TNT With or Without Chlorophyllin

NCT05856305Rectal Neoplasms

DrugChlorophyllin, Sodium Copper Complex

Tata Memorial Centre

Phase 2

Mumbai, Navi Mumbai

2023-07-05

Recruiting

Postoperative Hypofractionated Radiation in Cervical and Endometrial Tumours: Phase II Study

NCT05857631Cervical Cancer, Endometrial Cancer

DrugCisplatin

Tata Memorial Centre

Not applicable

Navi Mumbai, Mumbai

2023-05-29

Active, closed

Validating Artificial Intelligence Effectiveness Defined Lung Nodule Malignancy Score in Patients With Pulmonary Nodule.

NCT05817110Lung Malignancy

AstraZeneca

Observational

712

Gurugram, New Delhi, Hyderabad, Bangalore, Chennai, Kolkata, Mumbai, Pune

2023-04-20

Recruiting

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

NCT05774951Breast Cancer, Early Breast Cancer

DrugsCamizestrant·Tamoxifen·Exemestane·Anastrozole

AstraZeneca

Phase 3

4,300

Bangalore, Belagavi, Bhubaneswar, Hubli, Hyderabad, Jaipur, Kolkata, Mumbai

2023-03-31

Active, closed

A Study of TAR-200 in Combination With Cetrelimab or TAR-200 Alone Versus Intravesical Bacillus Calmette-Guérin (BCG) in Participants With BCG-naïve High-risk Non-muscle Invasive Bladder Cancer (HR-NMIBC)

NCT05714202Bladder Cancer

DrugsTAR-200·Cetrelimab

Janssen Research & Development, LLC

Phase 3

1,135

Bangalore, Chandigarh, Gurugram, Kolkata, Mumbai, Pune

2023-03-23

Recruiting

A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works

NCT05744921Paroxysmal Nocturnal Hemoglobinuria

DrugsCemdisiran·Pozelimab

Regeneron Pharmaceuticals

Phase 3

202

Kochi, Mumbai, New Delhi, Chandigarh, Jaipur

2023-03-07

Active, closed

A Study to Learn About a New Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People Who Have Advanced Metastatic Breast Cancer

NCT05654623Advanced Breast Cancer

DrugsVepdegestrant·Fulvestrant

Pfizer

Phase 3

624

Gurgaon, Mumbai, Nashik, Thane, New Delhi, Kolkata

2023-03-03

Active, closed

A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A

NCT05685238Haemophilia A, Haemophilia A With Inhibitors

Novo Nordisk A/S

Phase 3

451

Surat, Mumbai, Pune, Ludhiana, Jaipur, Ranipet, Noida

2023-02-13

Active, closed

A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2)

NCT05552976Relapsed or Refractory Multiple Myeloma

DrugsMezigdomide·Carfilzomib·Dexamethasone

Bristol-Myers Squibb

Phase 3

606

Gurgaon, Bengaluru, Mumbai, Thane, New Delhi, Mohali, Chennai, Hyderabad

2023-01-10

Active, closed

Phase 2b Study of GSK4532990 in Adults With NASH

NCT05583344Nonalcoholic Fatty Liver Disease, Non-alcoholic Fatty Liver Disease

DrugGSK4532990

GlaxoSmithKline

Phase 2

284

Bhubaneswar, Chandigarh, Coimbatore, Guhawati, Mumbai, Nagpur, New Delhi, Secunderabad

2023-01-02

Recruiting

Erythropoietin for Neonatal Encephalopathy in LMIC (EMBRACE Trial)

NCT05395195Encephalopathy, Erythropoietin, Newborn Asphyxia

DrugErythropoietin

Imperial College London

Phase 3

504

Bangalore, Chennai, Chhatrapati Sambhajinagar, Hubli, Mumbai

2022-12-31

Recruiting

A Clinical Trial of Study Medicine (Marstacimab) in Pediatric Patients With Hemophilia A or Hemophilia B

NCT05611801Hemophilia A, Hemophilia B

DrugMarstacimab

Pfizer

Phase 3

100

Surat, Mumbai, Kolkata

2022-12-09

Active, closed

A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight

NCT05567796Obesity

DrugsCagrilintide·Semaglutide

Novo Nordisk A/S

Phase 3

3,400

Surat, Belagavi, Kozhikode, Mumbai, Nagpur, Pune, Delhi, Chandigarh

2022-11-01

Active, closed

A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity

NCT05556512Obesity, Overweight

DrugTirzepatide

Eli Lilly and Company

Phase 3

15,374

Ahmedabad, Bikaner, Hyderabad, Lucknow, Ludhiana, Mumbai, Nagpur, New Delhi

2022-10-11

Recruiting

Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy

NCT05283226Carcinoma, Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

DrugPaclitaxel

NATCO Pharma Ltd.

Phase 2

Mumbai, Pune, Hyderabad

2022-09-30

Recruiting

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

NCT05519085Relapsed or Refractory Multiple Myeloma

DrugsMezigdomide·Velcade·Pomalidomide·Bortezomib

Celgene

Phase 3

810

Ahmedabad, Gurugram, Belagavi, Mumbai, Madurai, Varanasi, Ludhiana, Puducherry

2022-09-20

Active, closed

A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

NCT05528510Colitis, Ulcerative

DrugsGuselkumab 1·Guselkumab 2·Guselkumab 3

Janssen Research & Development, LLC

Phase 3

418

Gurugram, Hyderabad, Manipal, Mumbai, Surat

2022-09-13

Recruiting

A Study to Learn More About How Safe Darolutamide is and How Well it Works Under Real World Conditions When Taken in Addition to Standard Androgen Deprivation Therapy (ADT) in Indian Participants With High-risk Non-metastatic Castration-resistant Prostate Cancer (nmCRPC)

NCT05348876Non-metastatic Castration-resistant Prostate Cancer

DrugDarolutamide

Bayer

Phase 4

Nadiād, Bengaluru, Kochi, Thiruvananthapuram, Vellalasseri, Amravati, Mumbai, New Delhi

2022-08-03

Active, closed

A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-PD-1 Compared to Anti-PD-1 Monotherapy as First-Line Treatment in Subjects With Unresectable/Metastatic Melanoma

NCT05732805Melanoma, Melanoma (Skin), Melanoma Stage III, Melanoma Stage IV

Biocad

Phase 3

270

Faridabad, Mangalore, Mumbai, Nagpur, Nashik, New Delhi, Pune, Sangli

2022-08-02

Active, closed

A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Crohn's Disease

NCT05242471Crohn's Disease

DrugsJNJ-78934804·Golimumab·Guselkumab

Janssen Research & Development, LLC

Phase 2

703

Ahmedabad, Bengaluru, Bhubaneswar, Chennai, Gūrgaon, Hyderabad, Mumbai, New Delhi

2022-07-22

Active, closed

A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)

NCT05296798Locally Advanced or Metastatic Breast Cancer

DrugsPhesgo·Giredestrant·Pertuzumab·Trastuzumab

Hoffmann-La Roche

Phase 3

922

Bangalore, Mumbai, Pune, New Delhi, Kolkata

2022-07-18

Active, closed

Effect of a FLUid Bolus or a Low Dose VAsopressor Infusion on Cardiovascular Collapse Among Critically Ill Adults Undergoing Tracheal Intubation.

NCT05318066Critically Ill Adults in the ICU, Requiring Endotracheal Intubation

Tata Memorial Centre

Not applicable

200

Mumbai

2022-07-15

Active, closed

A Study of GRC 54276 in Participants With Advanced Solid Tumors and Lymphomas.

NCT05878691Advanced Solid Tumor, Lymphoma

DrugsAtezolizumab·Pembrolizumab

Glenmark Specialty S.A.

Phase 1

320

Vijayawada, Visakhapatnam, Gurgaon, Bangalore, Bengaluru, Kannur, Chhatrapati Sambhajinagar, Mumbai

2022-06-28

Active, closed

Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

NCT04975997Multiple Myeloma

DrugsIberdomide·Bortezomib·Daratumumab·Dexamethasone

Celgene

Phase 3

939

Hyderabad, Bangalore, Ernākulam, Mumbai, Kolkata, Puducherry

2022-06-23

Active, closed

To Check Safety of Ayurvedic Oral Cannabis in Breast and Head and Neck Cancer

NCT05969314Breast Cancer, Oral Cancer

DrugCannabis

Tata Memorial Hospital

Phase 1

Mumbai

2022-06-08

Active, closed

Cross-cultural Adaptation and Validation of the Localised Scleroderma Quality of Life Instrument (LoSQI) in Juvenile Localised Scleroderma (JLS)

NCT07908108Scleroderma

Istituto Giannina Gaslini

Observational

272

Mumbai

2022-05-18

Active, closed

Evaluate Durvalumab and Tremelimumab +/- Lenvatinib in Combination With TACE in Patients With Locoregional HCC

NCT05301842Hepatocellular Carcinoma

DrugsTremelimumab·Durvalumab·Lenvatinib

AstraZeneca

Phase 3

760

Ahmedabad, Bangalore, Delhi, Hyderabad, Jaipur, Kolkata, Mumbai, New Delhi

2022-03-28

Active, closed

A Research Study on How Well Concizumab Works for You if You Have Haemophilia A or B With or Without Inhibitors

NCT05135559Haemophilia A and B With and Without Inhibitors

DrugConcizumab

Novo Nordisk A/S

Phase 3

153

Guwahati, Surat, Kolhāpur, Mumbai, Pune, Cuttack, Jaipur, Noida

2022-03-24

Active, closed

Lutetium 177Lu-Edotreotide Versus Best Standard of Care in Well-differentiated Aggressive Grade-2 and Grade-3 GastroEnteroPancreatic NeuroEndocrine Tumors (GEP-NETs) - COMPOSE

NCT04919226Neuroendocrine Tumors

DrugsFOLFOX (Folinic acid·Everolimus·Fluorouracil·Oxaliplatin

ITM Solucin GmbH

Phase 3

259

Bangalore, New Delhi, Mumbai

2021-12-21

Active, closed

A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC)

NCT04819100Carcinoma, Non-Small-Cell Lung

DrugSelpercatinib

Eli Lilly and Company

Phase 3

152

Thiruvananthapuram, Mumbai, Nagpur, Nashik, New Delhi

2021-12-20

Active, closed

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-1)

NCT05147220Relapsing Multiple Sclerosis

DrugsTeriflunomide·Remibrutinib

Novartis Pharmaceuticals

Phase 3

1,000

Mangalore, Mumbai, Nashik, New Delhi, Chandigarh, Ludhiana, Lucknow, Dehradun

2021-12-16

Active, closed

Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure)

NCT04954859Hepatitis B

DrugBepirovirsen

GlaxoSmithKline

Phase 2

366

Belagavi, Coimbatore, Hyderabad, Kanchan Bagh Hyderabad, Mumbai, New Delhi, Pune, Surat

2021-12-14

Recruiting

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

NCT04892173Carcinoma, Squamous Cell

DrugsJNJ-90301900·Erbitux·Cetuximab

Johnson & Johnson Enterprise Innovation Inc.

Phase 3

500

Bangalore, Chennai, Madurai, Mumbai, Nashik, New Delhi, Pune, Vijayawada

2021-12-10

Recruiting

Radiotherapy vs Observation for Post Chemotherapy Residual Mass in Advanced Seminoma

NCT05142982Seminoma

Tata Memorial Centre

Not applicable

Mumbai, Navi Mumbai

2021-12-01

Not yet open

Surgery Vs Chemoradiation for Oropharyngeal Cancer- A Phase II/III Integrated Design Randomized Control Trial

NCT05144100Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8

Tata Memorial Centre

Phase 2/3

498

Mumbai

2021-12-01

Recruiting

Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

NCT05145127Hemophilia A, Hemophilia B

DrugMarstacimab

Pfizer

Phase 3

245

Surat, Mumbai, Pune, Kolkata

2021-11-17

Active, closed

A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure

NCT04988295Carcinoma, Non-Small-Cell Lung

DrugsLazertinib·Amivantamab·Pemetrexed·Carboplatin

Janssen Research & Development, LLC

Phase 3

776

Bangalore, Gurugram, Kolkata, Mumbai, Nashik, New Delhi, Pune, Thane

2021-11-17

Recruiting

Gross Examinations Versus Frozen Section for Assessment of Surgical Margins in Oral Cancers

NCT04809324Oral Cavity Cancer

Dr.Pankaj Chaturvedi

Not applicable

1,206

Mumbai, Navi Mumbai, Varanasi

2021-11-15

Recruiting

Clinical Outcomes and Quality of Life in Patients With Locally Advanced Vulvovaginal Cancers: Ambispective Registration Study.

NCT07179757Vulvo-vaginal Cancer

Tata Memorial Hospital

Observational

200

Mumbai

2021-10-30

Active, closed

A Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 Mutations

NCT05048797Locally Advanced or Metastatic Non-Small Cell Lung Cancer

DrugsTrastuzumab deruxtecan·Pemetrexed·Cisplatin·Carboplatin

AstraZeneca

Phase 3

454

Bangalore, Delhi, Hyderabad, Mumbai, Nashik

2021-10-28

Active, closed

A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer

NCT04975308Breast Neoplasms, Neoplasm Metastasis

DrugsImlunestrant·Exemestane·Abemaciclib·Fulvestrant

Eli Lilly and Company

Phase 3

874

Bangalore, Thiruvananthapuram, Mumbai, Nagpur, Nashik, Pune, Hyderabad

2021-10-04

Recruiting

Assessment of the Breast Cosmesis Using Deep Neural Networks: an Exploratory Study (ABCD)

NCT05450016Breast Cancer

Tata Memorial Centre

Observational

720

Mumbai

2021-10-04

Active, closed

A Study to Compare the Efficacy and Safety of Entrectinib and Crizotinib in Participants With Advanced or Metastatic ROS1 Non-small Cell Lung Cancer (NSCLC) With and Without Central Nervous System (CNS) Metastases

NCT04603807Carcinoma, Non-Small-Cell Lung

DrugsEntrectinib·Crizotinib

Hoffmann-La Roche

Phase 3

217

Kozhikode, Mumbai, New Delhi, Varanasi, Kolkata

2021-09-30

Active, closed

Assessment of Safety and Effectiveness of NovoSorb® BTM in Severe Burns

NCT04090424Burns

PolyNovo Biomaterials Pty Ltd.

Not applicable

150

Chhatrapati Sambhajinagar, Mumbai, Coimbatore

2021-09-21

Recruiting

Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs

NCT04613921Liver Diseases, Liver Cirrhosis, Acute-On-Chronic Liver Failure, Liver Transplant; Complications

European Foundation for Study of Chronic Liver Failure

Observational

3,000

Bengaluru, Mumbai, New Delhi, Jaipur, Chennai, Gurugramam, Kochi, Secunderabad

2021-07-08

Active, closed

Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC

NCT04821622Prostate Cancer

DrugsTalazoparib·Enzalutamide

Pfizer

Phase 3

599

Surat, Gurugram, Mumbai, Pune, New Delhi, Meerut, Kolkata

2021-05-12

Active, closed

A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy

NCT04873362Breast Cancer

DrugsTrastuzumab emtansine·Herceptin·Tecentriq·Trastuzumab

Hoffmann-La Roche

Phase 3

1,188

Ahmedabad, Bangalore, Mumbai, Nashik, Pune, New Delhi, North WEST Delhi, Ratnagiri Kilminnal

2021-05-04

Active, closed

Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)

NCT04822181Non-alcoholic Steatohepatitis

DrugSemaglutide

Novo Nordisk A/S

Phase 3

1,205

Secunderabad, Surat, Gurgaon, Mangalore, Mumbai, Nagpur, Delhi, Ghitorni

2021-04-01

Active, closed

Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

NCT04586023Relapsing Multiple Sclerosis

DrugsFenebrutinib·Teriflunomide

Hoffmann-La Roche

Phase 3

751

Ahmedabad, Mumbai, Pune, New Delhi, Ludhiana, Vadapalani, Chandigarh

2021-03-24

Recruiting

Compliance to Cervical Cancer Chemoradiation Guidelines: A Multicentric Implementation Audit and Resource Assessment Initiative of National Cancer Grid of India

NCT07290972Cervical Cancer Screening, Gynecologic Cancers, Treatment Compliance, Chemoradiotherapy

Tata Memorial Hospital

Observational

618

Mumbai

2021-02-01

Active, closed

A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)

NCT04624659Sickle Cell Disease

DrugEtavopivat

Forma Therapeutics, Inc.

Phase 3

450

Mumbai, Hyderabad, Bangalore, Cutack, New Delhi

2021-01-29

Active, closed

A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer

NCT04538742Metastatic Breast Cancer

DrugsTucatinib·Pertuzumab·Trastuzumab deruxtecan·Durvalumab

AstraZeneca

Phase 1/2

245

Delhi, Gūrgaon, Madurai, Mumbai

2020-12-28

Recruiting

Secukinumab Open Label Roll-over Extension Protocol

NCT04638647Autoimmunity, Inflammation

DrugSecukinumab

Novartis Pharmaceuticals

Phase 4

1,000

Surat, Bangalore, Mumbai, Nashik, New Delhi, Hyderabad

2020-12-22

Active, closed

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

NCT04607421Neoplasms

DrugsEncorafenib·Zirabev·Erbitux·Xeloda

Pfizer

Phase 3

841

Mumbai, Pune, Thane, New Delhi, Jaipur

2020-12-21

Active, closed

A Study of Osimertinib With or Without Chemotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer

NCT04351555Non-Small Cell Lung Cancer

DrugsTagrisso·Osimertinib·Pemetrexed·Cisplatin

AstraZeneca

Phase 3

358

Mumbai, Namakkal, New Delhi, Varanasi

2020-12-16

Recruiting

Observation or Upfront Cranial RT in Oncogene Mutated NSCLC With Asymptomatic BM: A Phase III RCT

NCT05236946Asymptomatic Brain Metastases, Driver Mutation Positive Non-small Cell Lung Cancer

Tata Memorial Hospital

Phase 3

190

Mumbai

2020-11-10

Active, closed

A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions

NCT04538664Carcinoma, Non-Small-Cell Lung

DrugsAmivantamab·Pemetrexed·Carboplatin

Janssen Research & Development, LLC

Phase 3

308

Hyderabad, Kolkata, Mumbai, Nashik, New Delhi, Pune

2020-10-13

Active, closed

A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312)

NCT04529772Diffuse Large B-Cell Lymphoma

DrugsAcalabrutinib·Vincristine·Doxorubicin·Prednisone

Acerta Pharma BV

Phase 3

611

Bangalore, Delhi, Kochi, Mumbai, Nashik, Pune

2020-10-08

Active, closed

A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

NCT04487080Carcinoma, Non-Small-Cell Lung

DrugsLazertinib·Amivantamab·Osimertinib

Janssen Research & Development, LLC

Phase 3

1,074

Hyderabad, Kolkata, Mumbai, Nashik, Pune

2020-09-30

Active, closed

A Study Comparing Savolitinib Plus Osimertinib vs Savolitinib Plus Placebo in Patients With EGFRm+ and MET Amplified Advanced NSCLC

NCT04606771Non-Small Cell Lung Cancer

DrugsSavolitinib·Osimertinib

AstraZeneca

Phase 2

Delhi, Mumbai

2020-09-28

Recruiting

A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

NCT04462770Dravet Syndrome

DrugClemizole HCl

Epygenix

Phase 3

150

Hyderabad, Surat, Belagavi, Bengaluru, Kochi, Pune, Mumbai, Nagpur

2020-09-15

Active, closed

Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery

NCT04498117Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Ovarian Cancer, Ovarian Serous Adenocarcinoma

DrugsOregovomab·Paraplatin·Taxol·Paclitaxel

CanariaBio Inc.

Phase 3

615

Bangalore, Bengaluru, Delhi, Mohali, Mumbai, Noida, Pune

2020-08-25

Active, closed

A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors

NCT04482309Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer, Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer

DrugTrastuzumab deruxtecan

AstraZeneca

Phase 2

477

Delhi, Gūrgaon, Kolkata, Mumbai

2020-08-18

Recruiting

Focal Radiotherapy Plus Low Dose Craniospinal Irradiation Followed by Adjuvant Chemotherapy in WNT Medulloblastoma.

NCT04474964Medulloblastoma, WNT-activated

Tata Memorial Centre

Not applicable

Mumbai

2020-08-13

Recruiting

Palliative Radiation for Advanced Cervical Cancer

NCT03997110Cervical Cancer

Tata Memorial Hospital

Not applicable

230

Mumbai

2020-06-19

Active, closed

KORTUC Phase II - Intra-tumoural Radiation Sensitizer in Patients With Locally Advanced/Recurrent Breast Cancer

NCT03946202Breast Cancer

DrugHydrogen Peroxide

Institute of Cancer Research, United Kingdom

Phase 2

184

Trivandrum, Vellore, Kolkata, Mumbai

2020-06-16

Active, closed

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

NCT04269200Endometrial Neoplasms

DrugsOlaparib·Durvalumab·Paclitaxel·Carboplatin

AstraZeneca

Phase 3

805

Hisar, Mumbai

2020-05-05

Recruiting

EORTC Metastatic Breast Cancer Module Development

NCT07806266Metastatic Beast Cancer

University of Leeds

Observational

568

Mumbai

2020-05-01

Recruiting

Standard Maintenance Therapy (SMT) vs Local Consolidative Radiation Therapy and SMT in OM-NSCLC

NCT05278052Oligometastatic Disease, Metastatic Non Small Cell Lung Cancer

Tata Memorial Hospital

Phase 3

190

Mumbai

2020-04-20

Recruiting

A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine Glioma

NCT04250064DIPG

DrugBevacizumab

Tata Memorial Centre

Phase 2

Mumbai

2020-02-04

Recruiting

First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1)

NCT04638790Hodgkin Lymphoma, Adult

DrugsABVD·Vinblastine·Bleomycin·Dacarbazine

State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia

Phase 3

300

Mumbai

2020-02-01

Recruiting

VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx Cancer

NCT04057209Glottis Tumor, Larynx Cancer

Olgun Elicin

Not applicable

Mumbai

2019-11-20

Recruiting

Local Consolidative Radiation Therapy Plus TKI Versus TKI Alone in Driver Mutated OM-NSCLC

NCT05277844Oligometastatic Disease, Non-small Cell Lung Cancer, Driver Mutation

Tata Memorial Hospital

Phase 2

106

Mumbai

2019-11-11

Recruiting

Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia

NCT04143724Beta-Thalassemia

DrugLuspatercept

Celgene

Phase 2

Hyderabad, Mumbai, Nagpur, Noida, Kolkata, Vellore

2019-11-07

Recruiting

PRRT Versus PRRT Plus Chemotherapy in GEP NET (PReCedeNT Trial)

NCT07185672Neuroendocrine Neoplasia's (NENs), Neuroendocrine Tumor GEP Grade 1-3, Neuroendocrine Gastroenteropancreatic Tumour

DrugCapecitabine

Tata Memorial Hospital

Phase 3

162

Mumbai, Navi Mumbai

2019-08-07

Active, closed

Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC

NCT03997123Triple Negative Breast Neoplasms

DrugsCapivasertib·Paclitaxel

AstraZeneca

Phase 3

923

Bangalore, Gūrgaon, Kolkata, Mumbai, Mysuru, Nagpur, Nashik, New Delhi

2019-06-25

Active, closed

ASP-1929 Photoimmunotherapy (PIT) Study in Recurrent Head/Neck Cancer for Patients Who Have Failed at Least Two Lines of Therapy

NCT03769506Head and Neck Cancer

Rakuten Medical, Inc.

Phase 3

135

Vadodara, Bangalore, Kochi, Chennai, Hyderabad, Kolkata, Mumbai

2019-05-09

Active, closed

A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes

NCT03811561Diabetes Mellitus, Type 2

DrugSemaglutide

Novo Nordisk A/S

Phase 3

1,500

Guntur, Surat, Bangalore, Kochi, Thiruvananthapuram, Thiruvnanthapuram, Mumbai, Nagpur

2019-05-08

Active, closed

Dietary Intake, Sarcopenic Obesity, and Other Treatment-Related Outcomes in Indian Children With Acute Lymphoblastic Leukemia

NCT03974893Sarcopenic Obesity

Columbia University

Observational

115

Mumbai

2019-04-18

Active, closed

Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1)

NCT03875235Biliary Tract Neoplasms

DrugDurvalumab

AstraZeneca

Phase 3

810

Gūrgaon, Kolkata, Mumbai, New Delhi

2019-04-16

Recruiting

Distribution of Lymph Node Metastases in Esophageal Carcinoma

NCT03222895Esophageal Neoplasms, Lymph Node Metastases

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Observational

5,000

Mumbai

2019-03-01

Active, closed

Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

NCT03650114Relapsing Multiple Sclerosis

Drugs13-valent pneumococcal conjugate vaccine·23-valent pneumococcal polysaccharide vaccine·Ofatumumab

Novartis Pharmaceuticals

Phase 3

1,882

Mangalore, Kochi, Mumbai, Pune, New Delhi, Chandigarh, Hyderabad, Howrah

2018-12-28

Active, closed

A Study of Neoadjuvant/Adjuvant Durvalumab for the Treatment of Patients With Resectable Non-small Cell Lung Cancer

NCT03800134Non-Small Cell Lung Cancer

DrugsDurvalumab·Pemetrexed·Gemcitabine·Paclitaxel

AstraZeneca

Phase 3

825

Ahmedabad, Gūrgaon, Kolkata, Manipal, Mumbai, Mysuru, Namakkal, Nashik

2018-12-06

Active, closed

A Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma

NCT03778957Hepatocellular Carcinoma

DrugsAvastin·Durvalumab·Bevacizumab

AstraZeneca

Phase 3

724

Bangalore, Bengaluru, Hyderabad, Kolkata, Madurai, Mumbai, Nashik, Pune

2018-11-30

Active, closed

Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrow

NCT03363373Neuroblastoma

DrugsNaxitamab·Gm-Csf

Y-mAbs Therapeutics

Phase 2

122

Mumbai

2018-04-03

Recruiting

iCaReMe Global Registry: Multinational Real-world Evidence in Cardiorenal and Metabolic Diseases

NCT03549754Type 2 Diabetes, Hypertension, Chronic Kidney Disease, Heart Failure

AstraZeneca

Observational

35,000

Ahmedabad, Kolkata, Mumbai

2018-02-17

Active, closed

Stereotactic Body Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Stage IIA-B Prostate Cancer

NCT03367702Stage II Prostate Adenocarcinoma AJCC v7

NRG Oncology

Phase 3

698

Mumbai

2018-02-01

Active, closed

A Prospective Evaluation of the Peri-operative Hypoxia in Breast Cancer

NCT03797482Breast Cancer Female

Tata Memorial Hospital

Observational

500

Mumbai

2017-11-27

Active, closed

Study of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma

NCT03298451Hepatocellular Carcinoma

DrugsSorafenib·Tremelimumab·Durvalumab

AstraZeneca

Phase 3

1,324

Bangalore, Bhubneshwar, Chennai, Hubli, Hyderabad, Karmsad, Mumbai, Nashik

2017-10-11

Active, closed

Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

NCT03180268Grade 2 Meningioma, Intracranial Meningioma

NRG Oncology

Phase 3

162

Mumbai

2017-09-12

Active, closed

Endocrine Therapy With or Without Abemaciclib (LY2835219) Following Surgery in Participants With Breast Cancer

NCT03155997Breast Cancer

DrugAbemaciclib

Eli Lilly and Company

Phase 3

5,637

Hyderabad, Ahmedabad, Vadodara, Gurgaon, Bangalore, Trivandrum, Mumbai, Nashik

2017-07-12

Recruiting

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

NCT03067181Childhood Extracranial Germ Cell Tumor, Extragonadal Embryonal Carcinoma, Germ Cell Tumor, Malignant Germ Cell Tumor

DrugsBleomycin·Cis-platinum·CDDP·Paraplatin

Children's Oncology Group

Phase 3

1,780

Mumbai

2017-05-25

Recruiting

Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

NCT03141021Malignant Peripheral Nerve Sheath Tumors

Washington University School of Medicine

Observational

1,050

Mumbai

2017-04-28

Active, closed

Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension

NCT02682511Scleroderma, Diffuse, Scleroderma, Systemic, Scleroderma, Limited, Sclerosis, Progressive Systemic

DrugIfetroban

Cumberland Pharmaceuticals

Phase 2

Chandigarh, Mumbai, Pune

2017-01

Active, closed

A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer

NCT02763566Breast Cancer

DrugsAnastrozole·Abemaciclib·Letrozole·Fulvestrant

Eli Lilly and Company

Phase 3

463

Ahmedabad, Bangalore, Mumbai, Pune, New Delhi, Ranipet, Kolkata

2016-12-05

Active, closed

Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection

NCT02932150Chronic Hepatitis B

Gilead Sciences

Phase 2

150

Kolkata, Lucknow, Mumbai, Nagpur, New Delhi, Surat, Varanasi

2016-11

Recruiting

Radiation Dose Optimization in Diffuse Large B- Cell Lymphoma.

NCT02964858NonHodgkin Lymphoma

Tata Memorial Hospital

Not applicable

840

Mumbai

2016-11

Active, closed

Perioperative Therapy Preoperative Chemotherapy Versus Chemoradiotherapy in Locally Advanced Gall Bladder Cancers

NCT02867865Gall Bladder Cancers

DrugsGemcitabine·Cisplatin

Tata Memorial Hospital

Phase 2/3

124

Mumbai

2016-09-06

Active, closed

Bladder Cancer Adjuvant Radiotherapy Trial

NCT02951325Bladder Cancer, Urothelial Carcinoma Bladder

Tata Memorial Centre

Phase 3

153

Mumbai

2016-06-02

Recruiting

Trial Evaluating Role of Post Mastectomy Radiotherapy in Women With Node Negative Early Breast Cancer

NCT02992574Breastcancer

Tata Memorial Centre

Not applicable

1,022

Chandigarh, Kolhāpur, Mumbai, Delhi, New Delhi, Jaipur

2016-05-27

Recruiting

An Audit of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

NCT02754115Colorectal Cancer, Ovarian Cancer, Peritoneal Disease

Tata Memorial Centre

Observational

400

Mumbai

2016-04

Active, closed

Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

NCT02227251Diffuse Large B-cell Lymphoma

DrugSelinexor

Karyopharm Therapeutics Inc

Phase 2

244

Patna, Vadapalani, Delhi, Thiruvananthapuram, Mumbai, Pune, New Delhi, Bhubaneswar

2014-11

Active, closed

A Study of Intravesical BCG in Combination With ALT-803 in Patients With Non-Muscle Invasive Bladder Cancer

NCT02138734Non-muscle Invasive Bladder Cancer

DrugAnktiva

ImmunityBio, Inc.

Phase 1/2

369

Visakhapatnam, Adyār, Ahmedabad, Chhatrapati Sambhajinagar, Nagpur, Pune, Mumbai, New Delhi

2014-07-21

Active, closed

Randomized Controlled Trial to Assess Blockade of Voltage Gated Sodium Channels During Surgery in Operable Breast Cancer

NCT01916317Operable Breast Cancer

Tata Memorial Hospital

Phase 3

1,600

Guwahati, Ahmedabad, Kannur, Kolhāpur, Mumbai, Pune, Sangli, Shillong

2011-12-12

Active, closed

Randomized Controlled Trial Evaluating the Role of Exercise in Women Undergoing Treatment for Breast Cancer

NCT02161900Non Metastatic Operable Breast Cancer

Tata Memorial Hospital

Not applicable

850

Mumbai

2010-11-12

Active, closed

A Randomized Controlled Trial of Neoadjuvant Weekly Paclitaxel Versus Weekly Paclitaxel Plus Weekly Carboplatin In Women With Large Operable or Locally Advanced, Triple Negative Breast Cancer

NCT03168880Triple Negative Breast Cancer

DrugsPaclitaxel·Carboplatin

Tata Memorial Hospital

Phase 3

720

Mumbai

2010-04

Active, closed

Comparison of Fulvestrant (FASLODEX™) 250 mg and 500 mg in Postmenopausal Women With Oestrogen Receptor Positive Advanced Breast Cancer Progressing or Relapsing After Previous Endocrine Therapy.

NCT00099437Breast Cancer

DrugFulvestrant

AstraZeneca

Phase 3

736

Ansārinagar, Bhopal, Hyderabad, Jaipur, Kolkata, Manipal, Marg Jaipur, Mumbai

2005-02-13

Recruiting

International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

NCT00358943Gaucher Disease, Cerebroside Lipidosis Syndrome, Glucocerebrosidase Deficiency Disease, Glucosylceramide Beta-Glucosidase Deficiency Disease

Genzyme, a Sanofi Company

Observational

12,000

Ahmedabad, Jaipur, Kolkata, Mumbai, Secunderabad, Vellore

1991-04-01

Cite this view

Priya Life Science (2026). Clinical trial register: studies with an Indian investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 7 November 2026. https://priyalifescience.com/clinical-trials-india/city/mumbai

Query this register directly

GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in India and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 1,120 studies in total at the last sync on 07 Nov 2026, 03:16 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 260 of those studies with a site in Mumbai.

How many clinical trials are recruiting in Mumbai?

146 of the 260 studies on this page are recruiting new participants as of the 07 Nov 2026, 03:16 UTC sync. A further 13 have not yet opened recruitment, 99 are active but closed to new participants, and 2 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Mumbai), 260 studies
Phase	Studies	Recruiting	Share
Phase 3	136	66	52.3%
Observational	33	26	12.7%
Phase 2	31	14	11.9%
Not applicable	28	21	10.8%
Phase 2/3	12	8	4.6%
Phase 4	12	8	4.6%
Phase 1	6	3	2.3%
Phase 1/2	2	0	0.8%

Most active sponsors

Lead sponsors with the most studies (Mumbai)
Lead sponsor	Studies	Recruiting
AstraZeneca	36	15
Tata Memorial Centre	32	27
Tata Memorial Hospital	22	15
Eli Lilly and Company	12	5
Novo Nordisk A/S	12	5
Pfizer	12	8
Bristol-Myers Squibb	11	8
Janssen Research & Development, LLC	9	2
Novartis Pharmaceuticals	8	4
Hoffmann-La Roche	7	2

Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.