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Trackers› Clinical trials› Virginia
Clinical trial register · United States · industry-sponsored

Clinical Trials in Virginia, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9118 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 06 Oct 2026, 03:16 UTC
9118
Studies in scope
industry-sponsored, all four open statuses
4945
Recruiting now
open to new participants
2189
Lead sponsors
across recruiting studies
Top states
California 5290 Florida 4430 Illinois 2481 Georgia 2368 Arizona 2238
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AstraZeneca19 Merck Sharp & Dohme LLC13 Janssen Research & Development, LLC8 Gilead Sciences7 Zimmer Biomet7
State
California5290 Florida4430 Illinois2481 Georgia2368 Arizona2238
All 51 states
Target enrolment
to

Trials with a site in Virginia

481 of 9118 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
Phase 1 Open-label Study of AMX-883 Alone in Participants With AML and High-risk MDS and in Combination in Participants With AML
NCT07723703Acute Myeloid Leukaemia, High Risk Myelodysplastic Syndrome
DrugPosaconazole
Amphista Therapeutics Ltd
Phase 1
54
Virginia
2026-10-16
Not yet open
A Study to Evaluate the Effect of ARGX-121 on the Change in Proteinuria in Adult Participants With IgAN
NCT07773727Immunoglobulin A Nephropathy (IgAN)
argenx
Phase 2
120
Florida, Texas, Virginia
2026-10-15
Not yet open
Symbiotic-GYN-18: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Advanced or Recurrent MMR-proficient Endometrial Cancer
NCT07578649Endometrial Neoplasms, Endometrial Cancer
DrugsPF-08634404·Keytruda·Pembrolizumab
Pfizer
Phase 3
600
Florida, Minnesota, Nevada, Ohio, Oregon, Tennessee, Texas, Virginia
2026-10-09
Not yet open
Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic
NCT07807345Head & Neck Squamous Cell Carcinoma, Non-Small Cell Lung Cancer, Esophageal Cancer, Gastric Cancer
DrugPembrolizumab
Sutro Biopharma, Inc.
Phase 1
285
California, Florida, Massachusetts, Oklahoma, Texas, Virginia
2026-09-14
Recruiting
A Study of AWT020 in Participants With Advanced Solid Tumors
NCT07822919Advanced Cancers (Solid Tumors)
DrugAWT020
Anwita Biosciences
Phase 1
96
Florida, Virginia
2026-09-11
Recruiting
Comparison of ACUVUE® OASYS MAX 1-Day Multifocal and DAILIES® AquaComfort Plus® Multifocal
NCT07788521Visual Acuity
Johnson & Johnson Vision Care, Inc.
Not applicable
150
Florida, Georgia, Missouri, New York, Rhode Island, Tennessee, Texas, Virginia
2026-09-10
Recruiting
Evaluation of Approved Contact Lenses (CR-6657)
NCT07819305Visual Acuity
Johnson & Johnson Vision Care, Inc.
Not applicable
150
Florida, Illinois, New York, Ohio, Tennessee, Texas, Virginia
2026-09-10
Recruiting
A Phase I/II Trial of JR-446 in Mucopolysaccharidosis Type IIIB (MPS IIIB)
NCT07640984Mucopolysaccharidosis IIIB
DrugJR-446
JCR Pharmaceuticals Co., Ltd.
Phase 1/2
12
California, Pennsylvania, Virginia
2026-09-09
Not yet open
A Study to Learn About the Safety and Immune Responses of RSVpreF in Older Adults
NCT07819097Adult, Healthy Participants
DrugRSVpreF
Pfizer
Phase 3
600
Connecticut, Ohio, Pennsylvania, Utah, Virginia
2026-09-09
Recruiting
A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety in Participants Aged 15 to 60 Years With Spinal Muscular Atrophy (SMA) Who Are Either New to SMA Treatment or Were Previously Treated With Risdiplam
NCT07444476Spinal Muscular Atrophy
DrugSalanersen
Biogen
Phase 3
90
California, Virginia
2026-09-08
Recruiting
A Phase 1, First-in-Human (FIH), Open-Label, Dose-Escalation and Dose Expansion Study of the Peptide Drug Conjugate (PDC), TS-104, as a Monotherapy in Subjects With Select Advanced Solid Tumors
NCT07814248NSCLC (Non-small Cell Lung Cancer), HNSCC, Endometrial, Ovarian Cancer
TwoStep Therapeutics, Inc.
Phase 1
74
Ohio, Oregon, Virginia
2026-09-02
Recruiting
A Study of ASP388B Given by Itself and With Standard Therapies in Participants With Solid Tumors
NCT07730021Locally Advanced or Metastatic Solid Tumors
DrugsAdrucil·Oxaliplatin·Carboplatin·Pembrolizumab
Astellas Pharma Global Development, Inc.
Phase 1/2
392
New York, Virginia
2026-09-02
Not yet open
A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1283 in Participants ≥6 Months to <12 Years of Age
NCT07808697SARS-CoV-2
DrugsMRNA-1283·Efluelda (TIV-HD) and Spikevax
ModernaTX, Inc.
Phase 2
300
California, Florida, Illinois, Michigan, Ohio, Texas, Utah, Virginia
2026-09-01
Not yet open
Chemotherapy With or Without IMD10 (Focused Ultrasound) in the Treatment of Borderline Resectable or Locally Advanced Pancreatic Cancer
NCT07325214Pancreatic Cancer, Borderline Resectable Pancreatic Cancer, Locally Advanced Pancreatic Cancer
IMGT Co., Ltd.
Not applicable
360
Massachusetts, Texas, Virginia
2026-09
Recruiting
REC-7735 in Participants With Solid Tumors
NCT07819136Solid Tumors
Recursion Pharmaceuticals Inc.
Phase 1/2
90
Michigan, Texas, Virginia
2026-09
Recruiting
A Study of Romiplostim Plus Predniso(lo)ne vs. Predniso(lo)ne Alone for the Treatment of Previously Untreated Primary Immune Thrombocytopenia (ITP)
NCT07700238Primary Immune Thrombocytopenia
DrugsPredniso(lo)ne·Nplate·Romiplostim
Amgen
Phase 3
126
California, Illinois, Virginia
2026-08-21
Not yet open
First-in-Human Trial of VBC106 in Participants With Advanced Solid Tumors
NCT07686068Participants With Advanced Solid Tumor Malignancies
VelaVigo Bio Inc
Phase 1/2
260
Texas, Utah, Virginia
2026-08-18
Recruiting
Study of NXP900 With Lorlatinib in ALK+ Lung Cancer
NCT07784959ALK Positive, ALK Positive Non-small Cell Lung Cancer, NSCLC, ALK+ Non-Small-Cell Lung Carcinoma
DrugsNXP900·Lorlatinib
Nuvectis Pharma, Inc.
Phase 1
54
Virginia
2026-08-17
Recruiting
A Study to Assess Safety and Efficacy of SOT109 in Patients With Advanced Unresectable or Metastatic Colorectal Cancer
NCT07693751Colorectal Cancer (Locally Advanced or Metastatic)
SOTIO Biotech a.s.
Phase 1/2
100
Texas, Virginia
2026-08-12
Recruiting
BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)
NCT07625644Small Cell Lung Cancer Extensive Stage, Small-cell Lung Cancer, Small Cell Carcinoma, Sclc
DrugsEtoposide·Atezolizumab·Carboplatin
SystImmune Inc.
Phase 3
550
Arkansas, California, Florida, New Jersey, Virginia
2026-08-04
Recruiting
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
NCT07745504Overweight, Obesity
DrugCagrilintide
Novo Nordisk A/S
Phase 3
285
Georgia, Hawaii, Illinois, Indiana, Kentucky, North Carolina, South Carolina, Virginia
2026-08-04
Recruiting
Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL
NCT07516093B-cell Lymphoma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
DrugsBexobrutideg·Pirtobrutinib
Nurix Therapeutics, Inc.
Phase 3
620
Georgia, Indiana, Tennessee, Texas, Virginia
2026-08-03
Recruiting
Cryoablation for Monomorphic Ventricular Tachycardia (VTS)
NCT07650032Ventricular Tachycardia, Sustained, Ventricular Tachycardia, Monomorphic
Adagio Medical
Not applicable
100
Arizona, California, Massachusetts, New York, Pennsylvania, South Carolina, Tennessee, Virginia
2026-08-01
Not yet open
A Phase 1/2 Study to Evaluate the Safety and Efficacy of Dibotatug (DR-01) in Adults With Bone Marrow Failure Syndromes
NCT07712562Bone Marrow Failure Syndromes, Aplastic Anemias, Severe Aplastic Anemia (SAA), Severe Aplastic Anemia, Relapse
DrugDibotatug
Dren Bio
Phase 1/2
60
California, Florida, Georgia, New York, Ohio, Texas, Virginia, Washington
2026-08
Not yet open
A Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety, Tolerability, and Clinical Activity of CBX-663 in Participants With Relapsed or Refractory Myeloid Malignancies, Advanced Solid Tumors, or Recurrent or Progressive Glioblastoma.
NCT07779798Advanced Solid Tumors, Recurrent or Progressive Glioblastoma, Relapse or Refractory Myeloid Malignancies
Crossbow Therapeutics, Inc.
Phase 1
120
Virginia
2026-08
Recruiting
First-in-Human Trial of VBC108 in Participants With Advanced Malignant Solid Tumors
NCT07700160Advanced Solid Tumors
VelaVigo Bio Inc
Phase 1/2
230
California, Michigan, New York, Texas, Virginia
2026-07-30
Recruiting
A Study to Evaluate ARV-6723 Alone and With Pembrolizumab in Participants With Advanced Solid Tumors
NCT07749586Advanced Solid Tumor
DrugPembrolizumab
Arvinas Inc.
Phase 1/2
499
North Carolina, Texas, Virginia
2026-07-29
Recruiting
Phase 1 Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of ARR-002 in Advanced or Metastatic Ovarian or Endometrial Cancer.
NCT07755436Ovarian Cancer, Endometrial Cancer, Platinum-resistant Ovarian Cancer (PROC), Metastatic Ovarian Cancer
ArriVent BioPharma, Inc.
Phase 1
180
Florida, Massachusetts, Tennessee, Texas, Virginia
2026-07-23
Recruiting
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Non-Small Cell Lung Cancer
NCT07659782Non-Small Cell Lung Cancer
DrugVS-7375
Verastem, Inc.
Phase 2
105
California, Florida, Georgia, New Jersey, New York, Texas, Virginia
2026-07-22
Recruiting
A Study of MX006 in Patients With Advanced and/or Metastatic Tumors Known to Express B7-H3
NCT07807241Advanced and/or Metastatic Solid Tumors Known to Express B7-H3
Myricx Pharma Limited
Phase 1
120
Florida, Texas, Virginia
2026-07-20
Recruiting
Phase 1/2 Study of BHB810 in Advanced Gastric and GEJ Adenocarcinoma
NCT07529808Gastric Cancer, Gastric Adenocarcinoma, Gastric (Stomach) Cancer, Gastroesophageal Adenocarcinoma
BigHat Biosciences, Inc.
Phase 1/2
164
California, Virginia
2026-07-16
Recruiting
Study of Lenacapavir, Teropavimab, and Zinlirvimab in Virologically Suppressed Adults With HIV-1 on Stable Oral Treatment Regimens
NCT07683000HIV-1-infection
DrugsTeropavimab·Zinlirvimab·Lenacapavir
Gilead Sciences
Phase 3
590
Michigan, Virginia
2026-07-14
Recruiting
Study of Lenacapavir, Teropavimab, and Zinlirvimab Versus Cabotegravir and Rilpivirine in Virologically Suppressed Adults With HIV-1 on Oral Daily Antiretroviral Therapy
NCT07682961HIV Infections
DrugsTeropavimab·Zinlirvimab·Rilpivirine·Cabotegravir
Gilead Sciences
Phase 3
590
California, Florida, Georgia, Michigan, Missouri, Texas, Virginia, Washington
2026-07-14
Recruiting
A Study to Investigate ANS02 in Participants With EGFR Mutation-Positive Non-Small Cell Lung Cancer
NCT07538804Non-Small Cell Lung Cancer
Avistone Biotechnology Co., Ltd.
Phase 1/2
294
Virginia
2026-07-10
Recruiting
A Study of VIRTUGUIDE System and DePuy Synthes Lapidus Implant in Participants Undergoing Lapidus Procedure
NCT07567092Hallux Valgus
DePuy Synthes Products, Inc.
Observational
100
Virginia
2026-07-07
Not yet open
A Comparison of a Medication Adherence Platform (FORTISKAP™) vs. Usual Care in Subjects on Oral Medications for the Treatment of Interstitial Lung Disease, Sarcoid and Pulmonary Hypertension
NCT07613216Idiopathic Pulmonary Fibrosis (IPF), Sarcoidosis Lung, Pulmonary Hypertension, Usual Interstitial Pneumonia
Cosmos Rx, Inc
Observational
100
Virginia
2026-07
Recruiting
A Study of ARC-02 in B-cell NHL
NCT07691606B-cell Non Hodgkin Lymphoma
DrugRituximab
Taiho Oncology, Inc.
Phase 1
140
California, Kentucky, New York, North Carolina, Virginia, Washington, Wisconsin
2026-06-22
Recruiting
A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015)
NCT07554339Non-small Cell Lung Cancer
DrugsCalderasib·Durvalumab
Merck Sharp & Dohme LLC
Phase 3
310
Illinois, Nebraska, New York, North Carolina, Virginia
2026-06-18
Recruiting
Water Vapor Ablation for Prostate Cancer: Long-Term Registry
NCT07455058Prostate Cancer
Francis Medical Inc.
Observational
2,500
Louisiana, Minnesota, Texas, Virginia
2026-06-05
Recruiting
Evaluation of a Non-Invasive Device for Early Detection of Atopic Dermatitis Flares
NCT07645820Atopic Dermatitis
Castle Biosciences Incorporated
Observational
450
Arizona, Maryland, Michigan, Missouri, Nevada, New Hampshire, Texas, Virginia
2026-06-04
Not yet open
A System to Help With Freezing of Gait in Parkinson's Patients
NCT07542743Freezing of Gait Symptoms in Parkinson Disease
Barron Associates, Inc.
Not applicable
60
Virginia
2026-06-01
Recruiting
Study of GB-4362 With Enfortumab Vedotin and Pembrolizumab for Advanced Urothelial Cancer
NCT07484022Advanced Urothelial Cancer, Metastatic Urothelial Carcinoma
DrugsEnfortumab Vedotin·Pembrolizumab
Generate Biomedicines
Phase 1
37
California, Florida, Georgia, Illinois, New Jersey, New York, Texas, Virginia
2026-06
Recruiting
Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors
NCT07524322Breast Cancer, Ovarian Cancer, Endometrial Cancer, PIK3CA Mutation
Regor Pharmaceuticals Inc.
Phase 1
63
California, Texas, Virginia
2026-06
Recruiting
Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HT31-1 for Treating ARDS
NCT07449572ARDS (Acute Respiratory Distress Syndrome)
HTIC, Inc
Phase 1
24
Virginia
2026-05-28
Recruiting
A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle
NCT06915233Chondral Defect, Articular Cartilage Defect
Vericel Corporation
Phase 3
309
California, District of Columbia, Kansas, North Carolina, Texas, Virginia
2026-05-28
Recruiting
Study of PM54 in Combination With Immunotherapy in Adult Participants With Advanced Malignancies
NCT07644039Advanced Malignancies
DrugsPM54·Pembrolizumab
PharmaMar
Phase 1/2
119
New York, Texas, Virginia
2026-05-21
Not yet open
AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
NCT07400107Obesity, Overweight, Diabetes Mellitus, Type 2
DrugsNNC0487-0111·Semaglutide
Novo Nordisk A/S
Phase 3
1,000
Florida, Georgia, Idaho, Maryland, Michigan, Texas, Virginia
2026-05-20
Recruiting
Study of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults With Advanced Colorectal Cancer
NCT07527858Advanced Microsatellite Stable Colorectal Cancer
DrugsDenikitug·Trifluridine/Tipiracil·Nivolumab·Bevacizumab
Gilead Sciences
Phase 2
170
Connecticut, Massachusetts, Missouri, South Dakota, Virginia
2026-05-19
Recruiting
Evaluation of Gixam's Efficacy Predicting the Presence of Advanced and Non-advanced Colorectal Neoplasia in a FIT Negative Population
NCT07623902CRC Screening, Microbiome
Jubaan Ltd.
Not applicable
1,436
Alabama, California, Florida, Illinois, New York, Ohio, Virginia
2026-05-18
Recruiting
A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants With Late-Onset Pompe Disease
NCT07354724Late-onset Pompe Disease
Denali Therapeutics Inc.
Phase 1
32
California, Missouri, North Carolina, Virginia
2026-05-12
Recruiting
A Study of TAK-505 in Adults With Solid Tumors
NCT07436728Malignant Solid Tumors
Takeda
Phase 1/2
151
California, Florida, Minnesota, New York, Ohio, Tennessee, Texas, Virginia
2026-05-11
Recruiting
NPX372, a B7-H7:CD3 Bispecific Antibody, in Selected Solid Tumor Malignancies
NCT07563829Metastatic Malignant Neoplasm
NextPoint Therapeutics, Inc.
Phase 1
81
California, Maryland, New York, Tennessee, Texas, Virginia
2026-05-01
Recruiting
Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy
NCT07502508Type 2 Diabetes
DrugIcovamenib
Biomea Fusion Inc.
Phase 2
60
Alabama, California, Florida, Georgia, Nevada, Ohio, Texas, Virginia
2026-04-30
Recruiting
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma
NCT07490301Metastatic Pancreatic Ductal Adenocarcinoma, PDAC
DrugsTelisotuzumab Adizutecan·Fluorouracil·Irinotecan·Oxaliplatin
AbbVie
Phase 2/3
900
Connecticut, Illinois, Michigan, Missouri, Ohio, Pennsylvania, Texas, Virginia
2026-04-30
Recruiting
A Study to Compare Setidegrasib (ASP3082) With Docetaxel, in People With Non-small Cell Lung Cancer With a KRAS G12D Mutation
NCT07566052Non-small Cell Lung Cancer (NSCLC)
DrugsSetidegrasib·Docetaxel
Astellas Pharma Global Development, Inc.
Phase 3
356
California, New Jersey, Virginia
2026-04-28
Recruiting
A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)
NCT07221669Muscular Atrophy, Spinal
DrugSalanersen
Biogen
Phase 3
30
Illinois, Texas, Virginia
2026-04-28
Recruiting
Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer
NCT07493512Metastatic Castration-resistant Prostate Cancer (mCRPC)
DrugXaluritamig
Amgen
Phase 1
40
Colorado, North Carolina, Ohio, Pennsylvania, South Dakota, Tennessee, Texas, Virginia
2026-04-28
Recruiting
A Study of NEOK002, an EGFR and MUC1 Targeting Bispecific ADC, in Participants With Select Solid Tumors
NCT07612189Locally Advanced (Unresectable) or Metastatic Solid Tumors
NEOK Bio, Inc.
Phase 1
155
Florida, New York, Tennessee, Texas, Virginia
2026-04-22
Recruiting
A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)
NCT07425522Diabetic Macular Edema
DrugFaricimab
Genentech, Inc.
Phase 1
93
Arizona, California, Florida, Maryland, Pennsylvania, Tennessee, Texas, Virginia
2026-04-21
Recruiting
Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC)
NCT07531095Small Cell Lung Cancer
DrugsZL-1310·Tarlatamab·Durvalumab
Amgen
Phase 1
160
Arizona, Florida, Illinois, Minnesota, New York, Tennessee, Virginia
2026-04-21
Recruiting
A Study of NEOK001, a B7-H3 and ROR1 Targeting Bispecific ADC in Participants With Select Solid Tumors
NCT07612176Locally Advanced (Unresectable) or Metastatic Solid Tumors
NEOK Bio, Inc.
Phase 1
155
New York, Tennessee, Texas, Virginia
2026-04-21
By invitation
A Study to Learn More About the Long-Term Safety and Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) or Microvascular Inflammation (MVI) (TRANSCEND/TRANSPIRE LTE)
NCT07444489Antibody-mediated Rejection, Microvascular Inflammation
DrugFelzartamab
Biogen
Phase 3
201
California, Minnesota, Missouri, Nebraska, New Jersey, Ohio, Pennsylvania, Virginia
2026-04-16
Recruiting
A Clinical Study Evaluating Licaminlimab for Dry Eye Disease
NCT07548632Dry Eye Disease (DED)
Oculis
Phase 2/3
160
California, Colorado, Florida, North Carolina, Pennsylvania, Tennessee, Virginia
2026-04-16
Recruiting
A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene) in Adult Participants With Late-Onset Pompe Disease (PROGRESS-GT LOPD)
NCT07282847Pompe Disease (Late-onset), Pompe Disease Late-Onset, LOPD
AskBio Inc
Phase 1/2
12
Arizona, California, New York, North Carolina, Pennsylvania, Texas, Virginia
2026-04-15
Recruiting
A Study of JNJ-101684362 (HLD-0117) in Patients With Metastatic Breast Cancer
NCT07524855Metastatic Breast Cancer
Janssen Research & Development, LLC
Phase 1
170
Connecticut, Florida, Massachusetts, Tennessee, Texas, Virginia
2026-04-09
Recruiting
Phase 1 Study of PF-08046033 in Advanced Solid Tumors
NCT07519655Non-Small-Cell Lung, Esophageal Cancer, Cutaneous Melanoma
Pfizer
Phase 1
250
Colorado, Connecticut, Tennessee, Virginia
2026-04-08
Recruiting
A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine
NCT07500506Lyme Disease
DrugVLA15
Pfizer
Phase 3
1,712
Maine, Massachusetts, New Jersey, New York, Pennsylvania, Rhode Island, Vermont, Virginia
2026-04-08
Recruiting
AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors
NCT07454642Vulvar Adenocarcinoma, PDAC - Pancreatic Ductal Adenocarcinoma, Gastric Adenocarcinoma, GEJ Adenocarcinoma
Avacta Life Sciences Ltd
Phase 1
174
Arizona, Florida, Illinois, Michigan, New York, Texas, Virginia
2026-03-31
Recruiting
AI-CARE: Artificial Intelligence for Cardiovascular Analysis and Risk Evaluation
NCT07438327Aortic Aneurysm, Aortic Aneurysm Abdominal, Aortic Aneurysm and Dissection, Aortic Aneurysm, Thoracoabdominal
Aiatella Oy
Observational
250
North Carolina, Virginia
2026-03-31
Recruiting
A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors
NCT07407933Thoracic Neoplasms, Lung Diseases, Small Cell Lung Carcinoma
DrugsTam-Peli·Atezolizumab
MediLink Therapeutics (Suzhou) Co., Ltd.
Phase 1/2
118
District of Columbia, Florida, Kentucky, Texas, Virginia
2026-03-31
By invitation
Open-Label Extension Study to Pioneer Study 6058-SCD-101
NCT07401823Sickle Cell Disease
Fulcrum Therapeutics
Phase 2
50
Arkansas, California, Louisiana, Massachusetts, New York, Texas, Virginia
2026-03-30
Recruiting
A 2-part Phase 1/2 Open-label Trial on ODM-212
NCT07563738Mesothelioma, Pancreatic Cancer, NSCLC (Advanced Non-small Cell Lung Cancer)
DrugsODM-212·Gemcitabine and nab-paclitaxel·Ipilimumab and nivolumab·Sotorasib
Orion Corporation, Orion Pharma
Phase 1/2
229
Texas, Virginia
2026-03-27
Recruiting
A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use
NCT07446439Nausea and Vomiting, Obesity
DrugTradipitant
Vanda Pharmaceuticals
Phase 3
280
California, Florida, New Jersey, New York, Texas, Virginia
2026-03-27
Active, closed
Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Who Are Not Achieving Glycemic Targets
NCT07502495Type 2 Diabetes
DrugIcovamenib
Biomea Fusion Inc.
Phase 2
64
Alabama, California, Florida, Georgia, Nevada, Ohio, Texas, Virginia
2026-03-27
Recruiting
A Trial to Investigate the Safety of E303 in Participants With Advanced Refractory Solid Tumors
NCT07524348Advanced Solid Tumors
Samsung Bioepis Co., Ltd.
Phase 1
149
Arizona, Virginia
2026-03-23
Recruiting
A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors
NCT07540572ER+, HER 2- Breast Cancer, Non-small Cell Lung Cancer (NSCLC), Castration-resistant Prostate Cancer (CRPC), Microsatellite Stable (MSS) Colorectal Carcinoma
DrugFulvestrant
IDEAYA Biosciences
Phase 1
160
Florida, New Jersey, New York, Texas, Utah, Virginia
2026-03-17
Recruiting
Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours
NCT07446855Solid Tumours
DrugSaruparib
AstraZeneca
Phase 1/2
180
New York, Rhode Island, Texas, Virginia
2026-03-17
Recruiting
Tacrolimus Ophthalmic Solution for the Treatment of Non-infectious Anterior Uveitis
NCT07285070Non-infectious Anterior Uveitis
Novaliq GmbH
Phase 2
20
Arizona, Florida, Massachusetts, New Jersey, Texas, Virginia
2026-03-16
Recruiting
A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea
NCT07235917Functional Hypothalamic Amenorrhea, FHA
DrugMibavademab
Regeneron Pharmaceuticals
Phase 2
34
Arizona, California, Connecticut, Florida, Oregon, Pennsylvania, Texas, Virginia
2026-03-11
By invitation
MDR - PMCF Study for RingLoc Bipolar Acetabular Cup and Endo II Femoral Heads
NCT05199870Hip Arthritis, Hip Disease, Hip Fractures, Hip Injuries
Zimmer Biomet
Observational
116
Virginia
2026-03-10
Recruiting
A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults
NCT07464314Influenza, Human+COVID-19
GlaxoSmithKline
Phase 1
225
Alabama, Arkansas, California, Florida, Georgia, Texas, Virginia, Washington
2026-03-09
Recruiting
A First-in-human Study of RLY-8161 in Advanced NRAS-Mutant Solid Tumors
NCT07584226Advanced NRAS-Mutant Melanoma, Advanced NRAS-Mutant Solid Tumors, NRAS Mutation, NRAS G12D
Relay Therapeutics, Inc.
Phase 1
35
California, Colorado, Massachusetts, Michigan, New York, Tennessee, Virginia
2026-03-09
Recruiting
A Study of Amivantamab and Olomorasib Combination Therapy in Participants With Metastatic Non-Small Cell Lung Cancer
NCT07227025Carcinoma, Non-Small-Cell Lung
DrugsOlomorasib·Amivantamab
Janssen Research & Development, LLC
Phase 1/2
60
New York, Virginia
2026-03-03
Recruiting
Phase I Study of SYS6043 in Patients With Advanced/Metastatic Solid Tumors
NCT07424547Cancer, Solid Tumor Cancer, Advanced Metastatic Cancer, Prostate
DrugSYS6043
Conjupro Biotherapeutics, Inc.
Phase 1
386
Florida, Texas, Virginia
2026-03-03
Recruiting
Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors
NCT07374848Solid Tumors, Sarcomas
Zai Lab (Shanghai) Co., Ltd.
Phase 1
180
California, Connecticut, Florida, Missouri, New York, Virginia
2026-03-02
Not yet open
The Effect of a Novel Joint Distraction Knee Orthosis for Treating Medial Knee Osteoarthritis
NCT07439315Medial Compartment Knee Osteoarthritis
Icarus Medical Innovations
Not applicable
150
Virginia
2026-03-01
Recruiting
COPD Exacerbation Follow Up
NCT07118306COPD (Chronic Obstructive Pulmonary Disease)
Viz.ai, Inc.
Observational
485
Illinois, New Jersey, Pennsylvania, Virginia, Wisconsin
2026-02-27
Active, closed
A Study to Assess the Effectiveness and Safety of IPN10200 in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows
NCT07427797Moderate to Severe Glabellar Lines
DrugCorabotase
Ipsen
Phase 3
309
Alabama, Arizona, California, Florida, Maryland, South Carolina, Texas, Virginia
2026-02-27
Recruiting
A Study of BI 3810944 in Patients With Advanced Cancer
NCT07224425Solid Tumours, Melanoma
Boehringer Ingelheim
Phase 1
69
Kentucky, Tennessee, Texas, Virginia
2026-02-24
Recruiting
A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types
NCT07503808Esophageal Squamous Cell Carcinoma, High Grade Serous Ovarian Cancer, Head and Neck Squamous Cell Carcinoma, Colorectal Cancer
IDEAYA Biosciences
Phase 1
150
Colorado, Florida, Michigan, New York, Tennessee, Texas, Utah, Virginia
2026-02-24
Recruiting
Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD
NCT07051707COPD, Chronic Obstructive Pulmonary Disease
Nuvaira, Inc.
Not applicable
200
Alabama, Florida, Michigan, North Carolina, Ohio, Pennsylvania, Virginia, Wisconsin
2026-02-24
Recruiting
A Clinical Trial Comparing 2x/Day for 30-minutes Use of the Emanate Perio PODS Post-SRP to a Control Group Post-SRP.
NCT06914596Periodontitis (Stage 3)
McGuire Institute
Not applicable
72
California, Connecticut, Massachusetts, Nebraska, Texas, Virginia, Washington
2026-02-19
Recruiting
Aspiration Thrombectomy Using the Symphony or Prodigy System
NCT07350499Arterial Thromboembolism, Venous Thromboembolism, Pulmonary Embolism
Imperative Care, Inc.
Observational
750
Alabama, Florida, Illinois, Indiana, Michigan, New York, Ohio, Virginia
2026-02-13
Recruiting
A Study of Patients With Fabry Disease (US Specific)
NCT06906367Fabry Disease
DrugMigalastat HCl
Amicus Therapeutics
Observational
450
Alabama, Arkansas, Georgia, Missouri, New York, Pennsylvania, Texas, Virginia
2026-02-13
Recruiting
Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea
NCT07285785Diarrhea, Gastroenteritis, Bacterial Infection, Acute Diarrhea
DrugRifaximin
Bausch Health Americas, Inc.
Phase 4
54
California, Florida, Georgia, Illinois, Oregon, Texas, Virginia
2026-02-11
Recruiting
A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors
NCT07287995Locally Advanced or Metastatic Malignant Solid Tumors
DrugsEnfortumab Vedotin·Keytruda·Carboplatin·Pembrolizumab
Astellas Pharma Global Development, Inc.
Phase 1/2
428
New Jersey, New York, Tennessee, Virginia
2026-02-05
Recruiting
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)
NCT07222332Diabetes Mellitus, Type 1
DrugBaricitinib
Eli Lilly and Company
Phase 3
300
Colorado, Florida, Pennsylvania, Texas, Virginia
2026-02-05
Recruiting
Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors
NCT07397338Advanced Solid Tumors, Metastatic Solid Tumors, Non-small Cell Lung Cancer (NSCLC), NSCLC
DrugsElironrasib·Zoldonrasib·Ivonescimab·Cetuximab
Revolution Medicines, Inc.
Phase 1/2
370
California, Connecticut, Minnesota, Tennessee, Texas, Virginia
2026-01-30
Active, closed
Effects of a Topical Serum Solution on Hair Characteristics
NCT07785869Hair Characteristics
DrugMinoxidil
Pacagen, Inc.
Not applicable
190
New Jersey, Virginia
2026-01-26
Recruiting
Study of ABBV-142 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Idiopathic Pulmonary Fibrosis
NCT07230288Idiopathic Pulmonary Fibrosis
AbbVie
Phase 2
165
Alabama, Florida, Illinois, Michigan, Missouri, Pennsylvania, Virginia
2026-01-23
Recruiting
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer
NCT07321106Colorectal Cancer, Colorectal Cancer (CRC), Colorectal (Colon or Rectal) Cancer, CRC
Cartography Biosciences
Phase 1
80
Arizona, California, Florida, Georgia, Michigan, Texas, Virginia
2026-01-15
Recruiting
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults
NCT07222137Diabetes Mellitus, Type 1
DrugBaricitinib
Eli Lilly and Company
Phase 3
150
California, Florida, Iowa, Kentucky, Pennsylvania, Virginia
2026-01-12
Recruiting
A First-in-Human Study of MEN2501 in Participants With Platinum-Resistant Ovarian Cancer
NCT07226427Platinum-resistant Ovarian Cancer
Stemline Therapeutics, Inc.
Phase 1
100
Arkansas, Connecticut, Florida, Massachusetts, Michigan, Minnesota, Virginia
2026-01-10
Recruiting
A Study of Migalastat in Pediatric Subjects (2 to <12 Yrs) With Fabry Disease and Amenable GLA Variants
NCT06904261Fabry Disease
DrugMigalastat HCl
Amicus Therapeutics
Phase 3
8
Georgia, Minnesota, North Carolina, Ohio, Pennsylvania, Virginia
2026-01-08
Recruiting
Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors
NCT07349537Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC), Pancreatic Adenocarcinoma, Pancreatic Ductal Adenocarcinoma (PDAC)
DrugCetuximab
Revolution Medicines, Inc.
Phase 1
574
Connecticut, Maryland, Massachusetts, Michigan, New York, Texas, Virginia
2026-01-08
Not yet open
ADO-5030 in Bronchoconstriction Challenge, Phase 1b
NCT07281274Asthma (Diagnosis)
Adovate
Phase 1
36
Virginia
2026-01-01
Not yet open
Milky Way Sensor: Device Validation for Infiltrated Tissues
NCT07311733Infiltration of Peripheral IV Therapy
ivWatch, LLC
Not applicable
28
Virginia
2026-01
Recruiting
DPTX3186 in Wnt Pathway Activated Solid Tumors
NCT07312903Solid Tumors
Dewpoint Therapeutics
Phase 1
40
Texas, Virginia
2026-01
Recruiting
Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders
NCT07104565Immune Thrombocytopenia
Incyte Corporation
Phase 2
56
Arizona, California, Colorado, Connecticut, Florida, Massachusetts, New York, Virginia
2025-12-29
Recruiting
Study of NXP900 With Osimertinib in Subjects With Advanced, EGFR-Mutated Non-Small Cell Lung Cancer
NCT07315113EGFR Mutation Positive Non-small Cell Lung Cancer, EGFR Mutated Non-small Cell Lung Cancer Patients
DrugsNXP900·Osimertinib
Nuvectis Pharma, Inc.
Phase 1
18
Maryland, Massachusetts, Oregon, Pennsylvania, Texas, Virginia
2025-12-18
Recruiting
A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)
NCT07247110Malignant Neoplasm
DrugsCetuximab·Keytruda·Pembrolizumab
Merck Sharp & Dohme LLC
Phase 1
250
New Jersey, Texas, Virginia
2025-12-16
Recruiting
Phase 1 Study of Intravaginal KB15A
NCT07222020Healthy Subjects
ZabBio Inc.
Phase 1
24
Virginia
2025-12-16
Recruiting
A Non-Randomized Open Label Clinical Trial Evaluating DermaBind TL
NCT07172893Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU)
HealthTech Wound Care
Phase 4
150
Florida, Michigan, North Carolina, Ohio, Texas, Virginia
2025-12-10
Recruiting
Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer
NCT07226999Small Cell Lung Cancer (SCLC)
DrugsPF-08634404·Atezolizumab
Pfizer
Phase 2/3
550
Arkansas, Florida, Ohio, Texas, Virginia
2025-12-09
Recruiting
A Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Activity of IPN60300 in Adults With Locally Advanced or Metastatic Solid Tumours
NCT07213817Locally Advanced Solid Tumor, Metastatic Solid Tumor
Ipsen
Phase 1/2
114
Connecticut, Michigan, Pennsylvania, Texas, Virginia
2025-12-05
By invitation
Study of Lotilaner Ophthalmic Gel in Patients With Ocular Rosacea (KORE)
NCT07443202Ocular Rosacea
Tarsus Pharmaceuticals, Inc.
Phase 2
155
Texas, Virginia
2025-12-05
Recruiting
A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014)
NCT07209111Neoplasm Malignant
DrugsCalderasib·Cetuximab
Merck Sharp & Dohme LLC
Phase 2
150
Maryland, Michigan, Nevada, New Jersey, Utah, Virginia
2025-12-04
Recruiting
A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC)
NCT07244341Metastatic Castration-resistant Prostate Cancer
DrugsValemetostat·Darolutamide
Daiichi Sankyo
Phase 1
60
California, Massachusetts, Michigan, New York, South Carolina, Texas, Virginia, Wisconsin
2025-12-03
Recruiting
A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors
NCT07317505Cancer, Cancer (Solid Tumors)
DrugJMT108
Conjupro Biotherapeutics, Inc.
Phase 1
270
North Carolina, Texas, Virginia
2025-12-02
Recruiting
A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous (IV) ABBV901 Moves Through the Body Alone or in Combination With Other Anticancer Drugs in Adult Participants With Ovarian Cancer
NCT07278336Ovarian Cancer
DrugsBevacizumab·Carboplatin
AbbVie
Phase 1
285
California, Colorado, Illinois, Nebraska, Texas, Utah, Virginia
2025-11-27
Recruiting
A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions.
NCT07225751Ankle Arthrodesis or Arthroplasty, Hindfoot Fusion, Ankle Deformity, Ankle Disease
Kuros Biosurgery AG
Not applicable
126
California, Colorado, Georgia, North Carolina, Pennsylvania, Tennessee, Virginia
2025-11-25
Recruiting
A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies
NCT07223047Advanced Solid Malignancies, Non-small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC), Pancreatic Ductal Adenocarcinoma (PDAC)
DrugsCetuximab·Nab-paclitaxel·Gemcitabine·Pembrolizumab
Bristol-Myers Squibb
Phase 1/2
252
Maryland, Texas, Utah, Virginia
2025-11-25
Recruiting
A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy
NCT07161414Advanced Solid Tumors
DrugsRecombinant Human Hyaluronidase·Rilvegostomig
AstraZeneca
Phase 1
40
North Carolina, Texas, Virginia
2025-11-25
Recruiting
A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors
NCT07300150Colorectal Cancer, Pancreatic Cancer, Non-Small Cell Lung Cancer, Solid Tumor
DrugCetuximab
PAQ Therapeutics, Inc.
Phase 1
210
Massachusetts, Texas, Utah, Virginia
2025-11-21
Recruiting
Evaluate the Safety, Tolerability, and Preliminary Efficacy of EVM14 Alone and in Combination in Patients With Selected Solid Tumors
NCT07095868Selected Types of Solid Tumor
Everest Medicines (Beijing) Co., Ltd.
Phase 1/2
94
New York, Texas, Virginia
2025-11-17
Recruiting
Assessment of CSF Shunt Flow During Activities of Daily Living and Sleep With a Thermal Measurement Device
NCT07050628Hydrocephalus
Rhaeos, Inc.
Not applicable
28
Illinois, Virginia
2025-11-10
Recruiting
A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors
NCT07181681Solid Tumors, Advanced Solid Tumor
BeOne Medicines
Phase 1
63
Texas, Virginia
2025-11-10
Recruiting
A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer
NCT07227168Head and Neck Squamous Cell Carcinoma HNSCC, Non-Small Cell Lung Cancer NSCLC, Esophageal Cancer, Gastric Cancer
DrugPembrolizumab
Sutro Biopharma, Inc.
Phase 1
200
California, Colorado, District of Columbia, Florida, Massachusetts, New York, Texas, Virginia
2025-11-07
Active, closed
Weight Loss in People Living With Overweight or Obesity Following Treatment With Cagrilintide
NCT07220642Obesity, Overweight
DrugCagrilintide
Novo Nordisk A/S
Phase 3
300
California, Colorado, Florida, Illinois, Indiana, Missouri, North Carolina, Virginia
2025-11-05
Recruiting
Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)
NCT07123155Pompe Disease
Shionogi
Phase 2
45
California, Florida, Georgia, Missouri, North Carolina, Ohio, Pennsylvania, Virginia
2025-10-30
Recruiting
The HIgh-fidelity Hydraulic couPling Upper-arm Cuff Assessment of Limits, Safety, and Effectiveness (HIPULSE) Trial (Cardiac Output Study)
NCT06895603ICU, Pulmonary Artery Catheter (PAC), Swan-Ganz Catheter
Philips Clinical & Medical Affairs Global
Observational
75
Virginia
2025-10-28
Active, closed
Comparability Trial of the MVA-BN Vaccine Manufactured in Different Production Cells
NCT07199569Monkeypox (Mpox)
DrugJynneos
Bavarian Nordic
Phase 2
970
Iowa, Kansas, New York, North Carolina, South Carolina, Tennessee, Texas, Virginia
2025-10-27
Recruiting
A Study of SGT-003 Gene Therapy in Ambulant Males With Duchenne Muscular Dystrophy (IMPACT DUCHENNE)
NCT07160634Duchenne Muscular Dystrophy
Solid Biosciences Inc.
Phase 3
80
Arkansas, Texas, Virginia
2025-10-22
Recruiting
ResQ133A-NMIBC: Intravesical Recombinant Mycobacterium (rMBCG) in Participants With NMIBC Eligible to Receive Intravesical Tice BCG
NCT06800963NMIBC
ImmunityBio, Inc.
Phase 1/2
40
Arizona, California, Georgia, Michigan, New York, Pennsylvania, Tennessee, Virginia
2025-10-15
Recruiting
Long-Term Stability of the Glide Control Strategy
NCT07222085Upper Limb Amputation Above Elbow, Upper Limb Amputation Below Elbow
Infinite Biomedical Technologies
Not applicable
12
Maryland, Massachusetts, North Carolina, South Carolina, Virginia
2025-10-15
Recruiting
Z1 Hip System: Post-Market Clinical Follow Up Study
NCT07104279Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck, Avascular Necrosis of the Femoral Head
Zimmer Biomet
Observational
300
North Carolina, Ohio, Oregon, Virginia
2025-10-13
By invitation
Novel On-body Evaluation of Cardiac Health for Oncology
NCT07158450Cardiotoxicity, Heart Failure
Skribe Medical
Observational
1,000
Colorado, Florida, Illinois, Louisiana, New York, Pennsylvania, Tennessee, Virginia
2025-10-09
Recruiting
A Study of DS5361b in Participants With Advanced Solid Tumors
NCT07182591Advanced Solid Tumor
DrugsKeytruda·Pembrolizumab
Daiichi Sankyo
Phase 1
192
Florida, Rhode Island, Texas, Virginia
2025-10-02
Recruiting
Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia
NCT04716452Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia, Refractory, Refractory/Relapse Acute Myeloid Leukemia
Keystone Nano, Inc
Phase 1
15
Virginia
2025-10-01
Recruiting
An Eight-Week Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry Eye
NCT07179055Dry Eye
Vanda Pharmaceuticals
Phase 2
160
California, Massachusetts, North Carolina, Tennessee, Virginia
2025-10
Recruiting
Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome
NCT06776783Respiratory Distress Syndrome, Pre-term Infants
Aerogen Pharma Limited
Phase 3
520
Arkansas, California, Florida, Indiana, New Jersey, New York, Texas, Virginia
2025-09-24
Recruiting
Stratagen Quantitative Prostate MRI Platform Pilot Study
NCT06985238Prostate Cancer
Stratagen Bio, Inc.
Not applicable
75
New York, Virginia
2025-09-24
Recruiting
First-in-Human Trial of VBC101 in Participants With Advanced Solid Tumor Malignancies
NCT07136779Participants With Advanced Solid Tumor Malignancies
VelaVigo Bio Inc
Phase 1/2
310
Michigan, Texas, Utah, Virginia
2025-09-23
Recruiting
A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors
NCT07141706Advanced/Metastatic Solid Tumors
DualityBio Inc.
Phase 1
253
California, Michigan, Pennsylvania, Texas, Virginia
2025-09-23
Recruiting
A Recovery and Lifespan Study Using INTERCEPT Red Blood Cells Prepared Using the INTERCEPT Blood System for RBCs With AS-1
NCT07015437Healthy Subjects
Cerus Corporation
Phase 2
120
Ohio, Virginia
2025-09-19
Recruiting
A Study to Investigate the Safety and Efficacy of KQB548 in Participants With Advanced Solid Malignancies
NCT07207707Solid Tumor Malignancies
Kumquat Biosciences Inc.
Phase 1
78
California, Colorado, Florida, Michigan, Ohio, Texas, Utah, Virginia
2025-09-16
Recruiting
Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR
NCT06689839Aortic Stenosis Treated With TAVI, Aortic Diseases
EnCompass Technologies, Inc.
Not applicable
500
Florida, Indiana, Michigan, Missouri, New York, Ohio, Virginia
2025-09-09
Recruiting
Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors
NCT07145255Prostate Cancer Castration-resistant Prostate Cancer, Breast Cancer, Colo-rectal Cancer, Lung Cancer (Non-Small Cell)
MBrace Therapeutics
Phase 1/2
150
California, Michigan, New Jersey, Texas, Utah, Virginia
2025-09-03
Recruiting
Study of GS-5319 Given Alone or in Combination in Adults With Solid Tumors
NCT07128303Advanced Solid Tumor
DrugsPemetrexed·Carboplatin·Pembrolizumab
Gilead Sciences
Phase 1
476
Massachusetts, Texas, Virginia
2025-08-28
Recruiting
A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors
NCT07169734Cervical Squamous Cell Carcinoma, Squamous Non-small-cell Lung Cancer, Colorectal Cancer, Intrahepatic Cholangiocarcinoma
Alentis Therapeutics AG
Phase 1/2
180
Arizona, California, Connecticut, Illinois, Kentucky, New Jersey, Texas, Virginia
2025-08-26
Recruiting
A Study to Evaluate Topical ATR04-484 for EGFRi-Associated Dermal Toxicity
NCT06830863EGFR Inhibitor-associated Rash
Azitra Inc.
Phase 1/2
32
Arkansas, Connecticut, New York, Ohio, Texas, Virginia
2025-08-25
Recruiting
A Study to Assess the Efficacy of WSD0922-FU in Patients With C797S+ Advanced Non-small Cell Lung Cancer
NCT06868485Non Small Cell Lung Cancer
DrugWSD0922-FU
Wayshine Biopharm, Inc.
Phase 2
40
California, Florida, Michigan, New Jersey, Ohio, Pennsylvania, Texas, Virginia
2025-08-18
Recruiting
Open-label Extension Study in Participants With Early Alzheimer's Disease
NCT07105709Alzheimer's Disease
GlaxoSmithKline
Phase 2
220
Florida, New Jersey, New York, North Carolina, Oklahoma, Texas, Virginia
2025-08-14
Recruiting
A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)
NCT07098338Non-Small Cell Lung Cancer
DrugsRamucirumab·Rilvegostomig·Dato-DXd
AstraZeneca
Phase 2
278
California, Georgia, Maryland, Texas, Virginia
2025-08-07
Recruiting
A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
NCT07115043Melanoma, Non-small Cell Lung Cancer, Squamous Cell Carcinoma (Skin), Renal Cell Carcinoma
DrugRilvegostomig
AstraZeneca
Phase 1/2
120
Michigan, Missouri, Pennsylvania, Texas, Virginia
2025-07-29
Recruiting
A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry Disease
NCT06328608Fabry Disease
Chiesi Farmaceutici S.p.A.
Phase 2/3
22
Arizona, Georgia, Iowa, Ohio, Utah, Virginia
2025-07-29
Recruiting
PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis
NCT06422871End Stage Renal Disease, Hemodialysis Access Failure
Merit Medical Systems, Inc.
Observational
100
District of Columbia, Florida, North Carolina, Pennsylvania, Texas, Virginia
2025-07-28
Recruiting
A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors
NCT07066657Locally Advanced or Metastatic Solid Tumors, Colorectal Cancer, Gastric Cancer, Pancreatic Cancer
DrugMRG007
ArriVent BioPharma, Inc.
Phase 1
572
California, Colorado, Florida, Tennessee, Texas, Virginia, Washington
2025-07-25
Recruiting
A Study to Investigate the Safety, Tolerability, and Efficacy of SAR446268, an Adeno-associated Viral Vector-mediated Gene Therapy in Participants Aged 10 to 55 Years of Age With Non-congenital Myotonic Dystrophy Type 1
NCT06844214Myotonic Dystrophy
Sanofi
Phase 1/2
32
Florida, New York, Pennsylvania, Virginia
2025-07-23
Active, closed
A Study to Investigate the Safety and Biodistribution of a Single Intrathecal (IT) Injection of INS1201 in Ambulatory Males With Duchenne Muscular Dystrophy (DMD)
NCT06817382Duchenne Muscular Dystrophy
Insmed Gene Therapy LLC
Phase 1
12
Arkansas, California, Georgia, New York, Ohio, Tennessee, Virginia
2025-07-22
Recruiting
A Study of PARG Inhibitor FORX-428 in Patients With Advanced Solid Tumors.
NCT07356453Advanced Solid Tumors
FoRx Therapeutics AG
Phase 1
40
California, Michigan, Missouri, Oregon, Texas, Virginia
2025-07-22
Recruiting
A Study of JNJ-95437446 in Participants With Advanced-Stage Solid Tumors
NCT07107230Advanced Stage Solid Tumors
DrugAmivantamab
Janssen Research & Development, LLC
Phase 1
400
Florida, New York, Tennessee, Virginia
2025-07-15
Active, closed
Visual Field Analysis With Artificial Intelligence
NCT06920290Glaucoma, Visual Field Defect
Sight Intelligence Engineering Corporation
Observational
100
Virginia
2025-07-01
Recruiting
Evaluation of Cataract Surgery Outcomes in Patients With Prior Laser Vision Correction Implanted With the CT LUCIA Lens
NCT07084545Postoperative Visual Outcomes Following Cataract Surgery in Patients With Prior Myopic Corneal Laser Vision Correction
Carl Zeiss Meditec AG
Observational
30
Texas, Virginia
2025-07
Recruiting
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)
NCT07082725Niemann-Pick Type C Disease
DrugNizubaglustat
Azafaros B.V.
Phase 3
72
California, Minnesota, Texas, Virginia
2025-06-30
Active, closed
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of GM1 Gangliosidosis or GM2 Gangliosidosis
NCT07082543Gangliosidoses, GM2, Gangliosidosis, GM1
DrugNizubaglustat
Azafaros B.V.
Phase 3
75
California, Minnesota, Texas, Virginia
2025-06-30
Recruiting
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis
NCT07054515Niemann-Pick Type C Disease, GM1 Gangliosidosis, GM2 Gangliosidosis
DrugNizubaglustat
Azafaros B.V.
Phase 3
147
California, Minnesota, Texas, Virginia
2025-06-30
Recruiting
A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease
NCT06998524Von Willebrand Disease, Type 3
DrugEmicizumab
Hoffmann-La Roche
Phase 3
75
California, Florida, Kentucky, Minnesota, Missouri, Virginia
2025-06-27
Active, closed
Matrion Decellularized Placental Membrane Versus Conventional Wound Management in Subjects With Diabetic Foot Ulcers
NCT07116876Diabetic Foot Ulcer (DFU), Lower Extremity
LifeNet Health
Not applicable
120
Arizona, California, Florida, Illinois, North Carolina, Texas, Virginia
2025-06-26
Recruiting
An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.
NCT07033026Colorectal Cancer, CRC (Colorectal Cancer), Cancer Cachexia
NGM Biopharmaceuticals, Inc
Phase 2
136
California, Florida, Maryland, New York, Ohio, Texas, Virginia, Wisconsin
2025-06-25
Active, closed
Safety of a Single, Intravitreal Injection of 6.0M jCell (Famzeretcel) in Retinitis Pigmentosa (RP)
NCT06912633Retinitis Pigmentosa
jCyte, Inc
Phase 2
31
Arizona, California, Florida, Illinois, New Jersey, New York, Texas, Virginia
2025-06-20
Recruiting
Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG
NCT07087613Hypertension, Pulmonary, Heart Failure With Reduced Ejection Fraction
Eko Devices, Inc.
Observational
3,850
Illinois, Virginia
2025-06-15
Recruiting
Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors
NCT06993844Advanced Solid Tumors, Advanced Breast Cancer
DrugFulvestrant
Ensem Therapeutics
Phase 1/2
233
California, Connecticut, Massachusetts, North Carolina, Texas, Virginia, Washington
2025-06-10
Active, closed
A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's Ataxia
NCT06953583Friedreich Ataxia
DrugsOmaveloxolone·Skyclarys
Biogen
Phase 3
255
California, Florida, Pennsylvania, Tennessee, Virginia, Washington
2025-06-09
Recruiting
Study of AUBE00 in Patients With Solid Tumors
NCT07030959Solid Tumors
DrugCetuximab
Chugai Pharmaceutical
Phase 1
130
Michigan, Texas, Virginia
2025-06-05
By invitation
Virtuos Bone Graft in Lumbar Fusion
NCT06686017Degenerative Disc Disease
Orthofix Inc.
Observational
150
Indiana, Michigan, Montana, North Carolina, South Carolina, Texas, Virginia
2025-06-05
Recruiting
A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
NCT06983743Metastatic Solid Tumors
DrugsPanitumumab·Abraxane·Nab-paclitaxel·Keytruda
Erasca, Inc.
Phase 1
600
California, Colorado, Florida, Massachusetts, New York, Texas, Virginia
2025-06-05
Recruiting
A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas
NCT06999187Triple Negative Breast Cancer, HER2-negative Breast Cancer, Non Small Cell Lung Cancer, Cervical Cancer
Dren Bio
Phase 1
96
Colorado, Florida, North Carolina, Oklahoma, South Carolina, Texas, Virginia
2025-06-03
Recruiting
A Clinical Study of Intismeran Autogene (V940) and Pembrolizumab (MK-3475) in People With Melanoma (V940-012/INTerpath-012)
NCT06961006Malignant Melanoma
DrugsIntismeran autogene·Keytruda·Pembrolizumab
Merck Sharp & Dohme LLC
Phase 2
160
Arkansas, California, New Jersey, Virginia, Washington
2025-05-29
Recruiting
Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I)
NCT06780098Lung Neoplasm
DrugsR-DXd·Ifinatamab Deruxtecan·Taxotere·Docetaxel
Merck Sharp & Dohme LLC
Phase 2
144
Kentucky, Maryland, Texas, Virginia
2025-05-28
Recruiting
A Study to Assess the Safety and Effectiveness of the UrOActive® Artificial Urinary sPHincter (AUS)
NCT06968741Stress Urinary Incontinence (SUI)
UroMems SAS
Not applicable
140
California, Minnesota, North Carolina, Ohio, Tennessee, Texas, Virginia
2025-05-19
Recruiting
A proof-of Concept Study to Assess Safety and Tolerability of HM15421/GC1134A in Patients With Fabry Disease
NCT06858397Fabry Disesase
GC Biopharma Corp
Phase 1/2
18
California, Kansas, Minnesota, Ohio, Pennsylvania, Virginia
2025-05-14
Recruiting
A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1)
NCT06905197Non Small Cell Lung Cancer
DrugsDZD6008·Sunvozertinib
Dizal Pharmaceuticals
Phase 1
140
New York, Virginia
2025-05-13
By invitation
Long-term Safety and Efficacy Evaluation of Lunsekimig in Adult Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Clinical Study
NCT06914908Chronic Rhinosinusitis With Nasal Polyps
DrugsLunsekimig·Mometasone furoate
Sanofi
Phase 2
71
California, Idaho, Oklahoma, Texas, Virginia
2025-05-12
Recruiting
Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of TGW101 in Participants With Advanced Solid Tumors
NCT06959706Advanced Solid Tumors
Tagworks Pharmaceuticals BV
Phase 1
50
Arizona, Massachusetts, Pennsylvania, Texas, Virginia
2025-05-07
Recruiting
STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas
NCT06975293Solid Tumor, Sarcoma, Leiomyosarcoma, Dedifferentiated Liposarcoma
STORM Therapeutics LTD
Phase 1/2
107
California, Massachusetts, Michigan, New York, Texas, Virginia
2025-05-05
Active, closed
Safety, Tolerability and Efficacy of Trichostatin A in Patients With Mild to Severe Onychomycosis
NCT07065773Onychomycosis of Toenail
DrugTrichostatin A
Vanda Pharmaceuticals
Phase 2
50
California, Colorado, Minnesota, Texas, Virginia
2025-05-05
Not yet open
Respiratory Oxygen Adherence Monitor for Chronic Obstructive Pulmonary Disease Patients
NCT06874101COPD, COPD - Chronic Obstructive Pulmonary Disease
Barron Associates, Inc.
Not applicable
100
Virginia
2025-05-01
Recruiting
A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer
NCT06926920Triple Negative Breast Cancer
DrugSacituzumab Govitecan
Gilead Sciences
Phase 1/2
100
California, Georgia, Kansas, Missouri, Tennessee, Texas, Virginia
2025-04-30
Recruiting
A Study of PARP1 Selective Inhibitor, EIK1004 (IMP1707) in Participants With Advanced Solid Tumors.
NCT06907043Advanced Solid Tumors
Eikon Therapeutics
Phase 1/2
130
Colorado, Florida, Massachusetts, Texas, Virginia
2025-04-30
By invitation
A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type I
NCT06926621Myotonic Dystrophy Type 1 (DM1)
DrugVX-670
Vertex Pharmaceuticals Incorporated
Phase 2
44
Missouri, Virginia
2025-04-28
Recruiting
Access Cannulation Trial II
NCT05490225Dialysis; Complications, Vascular Access Complication
Voyager Biomedical
Not applicable
100
Alabama, California, Massachusetts, New York, South Carolina, Texas, Virginia
2025-04-23
Recruiting
PAS 1ml Magtrace® for Sentinel Lymph Node Biopsy in Breast Cancer Patients
NCT06610539Breast Cancer
Endomagnetics Ltd.
Observational
184
North Carolina, Virginia
2025-04-22
Recruiting
A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine and a Marketed Measles, Mumps and Rubella Vaccine When Administered as Intramuscular Injection to Healthy Children 12 to 15 Months of Age
NCT06855160Chickenpox
DrugsMarketed varicella vaccine·Hepatitis A vaccine·MMR vaccine·PCV (pneumococcal conjugate vaccine) 13
GlaxoSmithKline
Phase 3
911
Arizona, California, Florida, Idaho, Ohio, Texas, Virginia
2025-04-17
By invitation
A Study to Learn About the Long-Term Health of Adult Participants From a Previous Study of a New Melanoma Treatment
NCT06848088Melanoma
DrugsFianlimab·Cemiplimab
Regeneron Pharmaceuticals
Phase 2
48
California, Colorado, Kansas, Michigan, New Jersey, Tennessee, Texas, Virginia
2025-04-14
Active, closed
A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD)
NCT06450639Duchenne Muscular Dystrophy
DrugSatralizumab
Hoffmann-La Roche
Phase 2
30
Arkansas, California, Georgia, Michigan, Texas, Virginia
2025-04-04
Recruiting
A Long-term Follow-up Study to Evaluate SKG0106 in the Treatment of Patients With nAMD
NCT06346600Neovascular (Wet) Age-related Macular Degeneration
Skyline Therapeutics
Observational
83
Massachusetts, Texas, Virginia
2025-04-02
Active, closed
A Study of Raludotatug Deruxtecan (R-DXd) in People With Gastrointestinal Cancers (MK-5909-005)
NCT06864169Gastrointestinal Cancer
DrugR-DXd
Merck Sharp & Dohme LLC
Phase 2
160
Connecticut, District of Columbia, Florida, Montana, New Jersey, Ohio, Virginia, Wisconsin
2025-04-01
Not yet open
Mitochondrial DNA Deletions in Plasma as a Diagnostic Aid for Females Presenting With Symptoms of Endometriosis
NCT06907550Endometriosis
Pearsanta, Inc
Observational
1,000
Virginia
2025-04
Recruiting
A Phase 2 Study of PTX 100 in Patients With Relapsed/Refractory CTCL
NCT06854653CTCL
Prescient Therapeutics, Ltd.
Phase 2
115
California, Connecticut, Massachusetts, New York, Virginia
2025-03-28
Recruiting
A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)
NCT06818643Advanced Solid Tumors, Malignant Neoplasm
DrugMK-3120
Merck Sharp & Dohme LLC
Phase 1/2
270
Alabama, Florida, New Jersey, Texas, Virginia
2025-03-25
Active, closed
Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)
NCT06788912Lung Neoplasm Malignant
DrugsSteroid mouthwash (dexamethasone·Acetaminophen·Ribociclib·Sacituzumab tirumotecan
Merck Sharp & Dohme LLC
Phase 2
60
Alabama, California, Colorado, Maryland, Oregon, Texas, Virginia
2025-03-20
Recruiting
Study of Patritumab Deruxtecan Plus Pembrolizumab With Other Anticancer Agents in Participants With High-Risk Early-Stage Triple-Negative or Hormone Receptor-Low Positive/HER-2 Negative Breast Cancer (MK-1022-010, HERTHENA-Breast-03)
NCT06797635Breast Neoplasms, Breast Cancer
DrugsPatritumab deruxtecan·Doxorubicin Hydrochloride·Epirubicin·Adriamycin
Merck Sharp & Dohme LLC
Phase 2
372
California, Illinois, Montana, Oregon, Tennessee, Texas, Virginia
2025-03-20
Recruiting
Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)
NCT06641362Bradycardia, Heart Failure, Ventricular Dysfunction
VDI Technologies
Observational
360
Arizona, Illinois, Minnesota, Ohio, Texas, Virginia
2025-03-18
Active, closed
A Study to Assess a New Medicine Called IPN01195 When Administered Alone in Adults With Advanced Solid Tumours
NCT06833008Advanced Solid Tumor
Ipsen
Phase 1/2
42
Michigan, Tennessee, Texas, Utah, Virginia
2025-03-14
Recruiting
A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
NCT06835569Cancer, PDAC - Pancreatic Ductal Adenocarcinoma, NSCLC (Non-small Cell Lung Cancer), CRC (Colorectal Cancer)
DrugsCisplatin/Carboplatin·MFOLFIRINOX·MFOLFOX6·Midazolam
Alterome Therapeutics, Inc.
Phase 1
448
Florida, Massachusetts, Missouri, New York, North Carolina, Tennessee, Texas, Virginia
2025-03-05
Active, closed
Study of Zelenectide Pevedotin in Participants With Advanced Breast Cancer
NCT06840483Breast Cancer
DrugZelenectide pevedotin
BicycleTx Limited
Phase 2
66
Maryland, Massachusetts, Missouri, New York, North Carolina, Oregon, Texas, Virginia
2025-03-03
Active, closed
A Phase 2 in Adult Subjects With Hereditary Angioedema
NCT06846398Hereditary Angioedema (HAE)
DrugBW-20805
Shanghai Argo Biopharmaceutical Co., Ltd.
Phase 2
25
Maryland, Missouri, North Carolina, Pennsylvania, Virginia
2025-02-28
Recruiting
ORIC-114 in Combination With Subcutaneous Amivantamab in Patients With EGFR Exon20 Insertion Mutant NSCLC
NCT06816992Solid Tumors, EGFR Exon 20 Insertion Mutations, NSCLC, EGFR-mutated NSCLC
DrugAmivantamab
ORIC Pharmaceuticals
Phase 1
76
New York, Virginia
2025-02-27
Recruiting
A Study of HS-20110 in Participants With Advanced Solid Tumors
NCT06892379Solid Tumors
DrugHS-20110
Hansoh BioMedical R&D Company
Phase 1
475
Florida, Indiana, North Carolina, Texas, Virginia
2025-02-26
Recruiting
Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)
NCT06686394Breast Neoplasms, Breast Cancer
DrugsOgivri·Herzuma·Patritumab deruxtecan·Tucatinib
Merck Sharp & Dohme LLC
Phase 1/2
81
Colorado, Massachusetts, New Jersey, South Carolina, Virginia
2025-02-26
Recruiting
A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-159642 in Participants With Advanced Solid Tumors
NCT06804824Advanced Solid Tumors
DrugsSotorasib·Trametinib
Vividion Therapeutics, Inc.
Phase 1
220
Michigan, Texas, Utah, Virginia
2025-02-25
Active, closed
A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01
NCT06770933Diabetic Retinopathy, NPDR - Non Proliferative Diabetic Retinopathy
Vantage Biosciences Ltd
Phase 2
100
California, Florida, Georgia, Maryland, Oregon, Pennsylvania, Virginia
2025-02-11
Recruiting
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Antitumor Activity of ALK202 in Participants with Advanced Solid Tumors
NCT06707610Advanced Cancer, Advanced Solid Tumor
Shanghai Allink Biotherapeutics Co., Ltd.
Phase 1
234
Florida, Virginia
2025-02-10
Active, closed
Pilot Study of IC14 (Atibuclimab), an Anti-CD14 Monoclonal Antibody, to Treat STEMI
NCT06678074STEMI, STEMI (ST Elevation MI), STEMI - ST Elevation Myocardial Infarction (MI), Stent Implantation
Implicit Bioscience
Phase 1/2
10
Missouri, Virginia
2025-02-06
Recruiting
A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit
NCT06805825Gastrointestinal Stromal Tumors, Small-cell Lung Cancer, Adenoid Cystic Carcinoma, Uveal Melanoma
Novelty Nobility, Inc.
Phase 1
67
Michigan, Ohio, Oregon, Texas, Virginia
2025-02-03
Active, closed
Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)
NCT06710132Solid Tumors, Gastric Cancer, Non-Small Cell Lung Cancer (NSCLC), Pancreatic Cancer
DrugM9140
EMD Serono Research & Development Institute, Inc.
Phase 1/2
184
California, District of Columbia, Florida, South Carolina, Tennessee, Texas, Virginia
2025-01-29
Active, closed
Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors
NCT06781983Advanced or Metastatic Solid Tumors
Innate Pharma
Phase 1
145
Massachusetts, New Jersey, New York, Texas, Virginia
2025-01-24
Recruiting
A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer
NCT06609005Advanced Metastatic Castration Resistant Prostate Cancer
Shenzhen Ionova Life Sciences Co., Ltd.
Phase 1/2
84
Arizona, California, Texas, Virginia, Washington
2025-01-23
Active, closed
Study to Evaluate Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-291 Moves Through the Body in Adult Participants With Non-Hodgkin's Lymphoma
NCT06667687Non-Hodgkin's Lymphoma
AbbVie
Phase 1
21
North Carolina, Oregon, Texas, Utah, Virginia
2025-01-16
Recruiting
IBI3001 in Participants With Unresectable, Locally Advanced or Metastatic Solid Tumors
NCT06349408Locally Advanced Solid Tumor
Fortvita Biologics (USA)Inc.
Phase 1
250
California, New Jersey, Texas, Virginia
2025-01-10
Recruiting
A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies
NCT06759649Neoplasm, Cancer, Malignant Tumors
DrugZimberelimab
Compugen Ltd
Phase 1
200
Connecticut, Massachusetts, Michigan, Tennessee, Texas, Virginia
2025-01-07
Recruiting
A Study of ADRX-0405 in Subjects With Select Advanced Solid Tumors
NCT06710379Solid Tumors
Adcentrx Therapeutics
Phase 1
68
California, Michigan, Minnesota, Texas, Utah, Virginia
2024-12-30
Recruiting
Clinical Trial Evaluating an Amnion Membrane Allograft for Use in the Management of Non- Healing Diabetic Foot Ulcers Versus Standard Of Care
NCT06767501Diabetic Foot Ulcers (DFUs)
Skye Biologics Holdings, LLC
Not applicable
100
Virginia
2024-12-28
Recruiting
Clinical Trial Evaluating an Amnion Membrane Allograft Intended for Use in the Management of Non- Healing Venous Leg Ulcers Versus Standard Of Care Alone
NCT06764953Venous Leg Ulcers
Skye Biologics Holdings, LLC
Not applicable
100
Virginia
2024-12-28
Recruiting
A Study of PT0253 in Participants With KRAS G12D Mutated Advanced Solid Tumors
NCT06797336Solid Tumor
DrugCetuximab
PAQ Therapeutics, Inc.
Phase 1
240
California, Massachusetts, Michigan, Tennessee, Texas, Utah, Virginia
2024-12-19
Recruiting
A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors
NCT06747585Squamous Non-small-cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Cervical Squamous Cell Carcinoma, Esophageal Squamous Cell Carcinoma
Alentis Therapeutics AG
Phase 1/2
170
Arizona, California, Connecticut, Illinois, Kentucky, New Jersey, Virginia
2024-12-16
Recruiting
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
NCT06597019Familial Hypercholesterolemia - Heterozygous
DrugInclisiran
Novartis Pharmaceuticals
Phase 3
60
California, District of Columbia, Florida, New York, Utah, Virginia, West Virginia
2024-12-09
Active, closed
SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization
NCT06550024Osteo Arthritis Knee, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
CrannMed
Not applicable
89
Alabama, California, Florida, North Carolina, Virginia
2024-11-28
Active, closed
Observational Study of Oral Atogepant to Evaluate Real-World Effectiveness in Adult Participants With Migraine
NCT06543914Migraine
AbbVie
Observational
1,314
Alabama, Arizona, California, Florida, Kentucky, New York, Pennsylvania, Virginia
2024-11-26
Recruiting
Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
NCT06651281Crohn Disease, Colitis, Ulcerative
DrugTulisokibart
Merck Sharp & Dohme LLC
Phase 3
1,380
Connecticut, Michigan, Missouri, New York, Texas, Virginia, Washington
2024-11-25
Recruiting
Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers
NCT06681428Diabetic Foot Ulcer (DFU), Chronic Foot Ulcers
Tides Medical
Not applicable
240
California, Florida, North Carolina, Ohio, Virginia
2024-11-14
Recruiting
PK, PD, Safety, and Efficacy Study of Gefurulimab in Pediatric Patients With AChR+ Generalized Myasthenia Gravis
NCT06607627Generalized Myasthenia Gravis, gMG
Alexion Pharmaceuticals, Inc.
Phase 3
12
District of Columbia, Virginia
2024-11-13
Recruiting
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection
NCT07024641Hepatitis B Virus Infection
GigaGen, Inc.
Phase 1
48
Arizona, California, Georgia, Iowa, Kansas, Maryland, Texas, Virginia
2024-11-13
Active, closed
Prospective Evaluation of the Tool-in-lesion Technology of the Galaxy System in Routine Clinical Practice
NCT06685133Lung Cancer, Lung; Nodule
Noah Medical
Observational
50
Tennessee, Virginia
2024-11-08
Recruiting
A Multi-Country Observational Study of Safety and Effectiveness of Elfabrio® in Fabry Patients
NCT06663358Fabry Disease
DrugPegunigalsidase-alfa
Chiesi Farmaceutici S.p.A.
Observational
100
Alabama, Georgia, Illinois, Iowa, Michigan, Virginia
2024-11-06
Recruiting
A Study of DM005 in Patients With Advanced Solid Tumors
NCT06515990Carcinoma, Non-Small-Cell Lung, Squamous Cell Carcinoma of Head and Neck, Solid Carcinoma
Doma Biopharmaceutical（Suzhou）Co., Ltd.
Phase 1/2
208
Michigan, Texas, Virginia
2024-10-31
Active, closed
A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations
NCT06644768Non-small Cell Lung Cancer, Lung Cancer
DrugsValemetostat·Valemetostat Tosylate·Keytruda·Pembrolizumab
Daiichi Sankyo
Phase 1/2
137
California, Florida, Kentucky, Minnesota, New York, Pennsylvania, Virginia
2024-10-30
Active, closed
A Study of ZW191 in Participants With Solid Tumors
NCT06555744Advanced Solid Tumors
Zymeworks BC Inc.
Phase 1
145
Connecticut, Ohio, Oklahoma, Texas, Virginia
2024-10-30
Recruiting
Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors
NCT06598800Advanced Solid Tumor
BeOne Medicines
Phase 1
153
New Jersey, Texas, Virginia, Wisconsin
2024-10-18
Active, closed
IC14 for Treatment of Acute Decompensated Heart Failure
NCT06556810Acute Decompensated Heart Failure
DrugAtibuclimab
Implicit Bioscience
Phase 1/2
10
Virginia
2024-10-17
Recruiting
Study of ATX-01 in Participants With DM1
NCT06300307Myotonic Dystrophy 1
ARTHEx Biotech S.L.
Phase 1/2
56
California, Florida, Iowa, Kansas, Virginia
2024-10-15
Active, closed
Prospective Case Collection Study of Contrast-Enhanced Mammography Imaging Acquired on a New Investigational Device
NCT06636539Breast Screening
Hologic, Inc.
Not applicable
75
Texas, Virginia
2024-10-14
Recruiting
A Phase 1/2, Open-label, Multicenter, FIH Study to Evaluate Safety, Tolerability, PK and Anti-tumor Activity of YH42946
NCT06616766NSCLC (Non-small Cell Lung Cancer), Solid Tumor
Yuhan Corporation
Phase 1/2
201
Virginia
2024-10-02
Recruiting
Use of the Neurolyser XR for the Treatment of Low Back Pain Related to Sacroiliitis
NCT06053255Sacroiliitis
FUSMobile Inc.
Not applicable
10
Virginia
2024-09-13
Recruiting
A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy
NCT06388707Drug Resistant Epilepsy, Epilepsy, Seizures, Focal, Seizure
NaviFUS Corporation
Phase 1/2
8
California, Massachusetts, Virginia
2024-09-13
Recruiting
Bone Mineral Density Agreement Study Between EOSedge™ Versus Traditional DXA
NCT06659055Healthy, Indicated for EOSedge Imaging
Alphatec Spine, Inc.
Not applicable
214
Arizona, California, Tennessee, Virginia
2024-09-11
Recruiting
A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Vaccine Formulations
NCT06585241SARS-CoV-2
ModernaTX, Inc.
Phase 4
1,144
Georgia, Louisiana, Mississippi, Nebraska, Virginia
2024-09-09
Active, closed
Study of TTX-MC138 in Subjects With Advanced Solid Tumors
NCT06260774Advanced Solid Tumor
TransCode Therapeutics
Phase 1/2
16
Texas, Utah, Virginia
2024-09-05
Recruiting
Study With [225Ac]Ac-FL-020 in mCRPC Participants
NCT06492122Metastatic Castration-resistant Prostate Cancer
DrugBlood samples for PK
Full-Life Technologies UK Limited
Phase 1
50
California, Ohio, Virginia
2024-08-30
Active, closed
A Study to Evaluate the Safety and Tolerability of Efgartigimod PH20 SC Given by Prefilled Syringe in Kidney Transplant Recipients With Antibody-Mediated Rejection (AMR)
NCT06503731Antibody-mediated Rejection
argenx
Phase 2
33
Alabama, California, Illinois, Nebraska, North Carolina, Ohio, Virginia, Washington
2024-08-30
Recruiting
A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events
NCT06500884Multiple Myeloma
DrugsRamantamig·Talquetamab
Janssen Research & Development, LLC
Phase 2
210
California, Colorado, Connecticut, New York, North Carolina, Ohio, Virginia, Washington
2024-08-26
Active, closed
A Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors
NCT06533059Cancer, Breast Cancer, Endometrial Cancer, Metastatic Cancer
Alterome Therapeutics, Inc.
Phase 1
110
California, Colorado, Florida, Massachusetts, Missouri, Tennessee, Texas, Virginia
2024-08-22
Active, closed
Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)
NCT06462183Adenoid Cystic Carcinoma, Colorectal Cancer
DrugLenvatinib
Rgenta Therapeutics Inc
Phase 1
105
Massachusetts, Michigan, New York, Texas, Virginia, Washington
2024-08-19
Recruiting
A Modular Phase 1/2 Study With CT7439 in Participants With Solid Malignancies
NCT06600789Solid Malignancies
Carrick Therapeutics Limited
Phase 1/2
50
Texas, Virginia
2024-08-16
Recruiting
Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors
NCT06532565Advanced Solid Tumors
DrugZimberelimab
Gilead Sciences
Phase 1
154
California, Massachusetts, Texas, Virginia
2024-07-26
Recruiting
Endocardial Mapping With the CoreMap EP Mapping System
NCT06529978Persistent Atrial Fibrillation
CoreMap Inc.
Not applicable
245
Florida, Vermont, Virginia
2024-07-25
Recruiting
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
NCT06440005Cancer, Advanced Cancer, Locally Advanced Carcinoma, Metastatic Solid Tumor
Angiex, Inc.
Phase 1
80
California, Florida, Missouri, Tennessee, Texas, Virginia
2024-07-22
Active, closed
A Trial to Learn if the Combination of Fianlimab, Cemiplimab, and Chemotherapy is Safe and Works Better Than the Combination of Cemiplimab and Chemotherapy in Adult Patients With Non-Small Cell Lung Cancer That Can be Treated With Surgery
NCT06161441Resectable Non-small Cell Lung Cancer
DrugsFianlimab·Cemiplimab·Paraplatin·Taxol
Regeneron Pharmaceuticals
Phase 2
195
Florida, Illinois, Kansas, Michigan, Missouri, New York, Oregon, Virginia
2024-07-16
Recruiting
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BTX-9341 in Advanced and/or Metastatic Breast Cancer
NCT06515470Breast Cancer
DrugFulvestrant
Biotheryx, Inc.
Phase 1
82
Minnesota, Nebraska, Texas, Utah, Virginia
2024-07-03
Active, closed
Transorb™ Self-Gripping Resorbable Mesh in High-risk Subjects Undergoing Open Repair of Ventral Hernia
NCT06449378Hernia, Hernia, Ventral, Hernia, Abdominal, Hernia Abdominal Wall
Medtronic - MITG
Not applicable
163
Illinois, Kentucky, North Carolina, Ohio, Virginia
2024-07-02
Recruiting
A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis
NCT06392386Generalized Myasthenia Gravis
DrugEfgartigimod PH20
argenx
Phase 2/3
12
North Carolina, Texas, Virginia
2024-06-28
Recruiting
A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors
NCT06307795Locally Advanced or Metastatic Solid Tumors
DrugANS014004
Avistone Biotechnology Co., Ltd.
Phase 1
63
California, Colorado, Florida, Michigan, New York, Texas, Virginia, Washington
2024-06-24
Recruiting
Enzalutamide Implants (Enolen) in Patients With Prostate Cancer
NCT06257693Prostate Adenocarcinoma
DrugEnzalutamide
Alessa Therapeutics Inc.
Phase 1
45
California, Illinois, Louisiana, Maryland, Oregon, South Carolina, Virginia, Wisconsin
2024-06-21
Recruiting
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
NCT06428409Colorectal Cancer, Pancreatic Ductal Adenocarcinoma, Biliary Tract Cancer
DrugsSacituzumab tirumotecan·Fluorouracil·Leucovorin·Adrucil
Merck Sharp & Dohme LLC
Phase 1/2
220
California, Colorado, District of Columbia, Florida, Georgia, New York, Texas, Virginia
2024-06-20
Recruiting
Atrial Flutter Ablation in the iCMR
NCT05904548Atrial Flutter Typical
Imricor Medical Systems
Not applicable
91
Maryland, Virginia
2024-06-20
Recruiting
Study of APR-1051 in Patients With Advanced Solid Tumors
NCT06260514Advanced Solid Tumor
Aprea Therapeutics
Phase 1
90
Ohio, Texas, Virginia
2024-06-13
Active, closed
A Phase 1/2 Study of OBI-992 in Subjects With Advanced Solid Tumors
NCT06480240Advanced Solid Tumor
OBI Pharma, Inc
Phase 1/2
117
California, Michigan, Texas, Virginia
2024-06-12
Recruiting
MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
NCT05037968Degenerative Disc Disease, Spine Fusion, Leg Pain and/or Back Pain
Kuros Biosurgery AG
Not applicable
100
Connecticut, Illinois, Maryland, Michigan, North Carolina, Ohio, Utah, Virginia
2024-06-10
Recruiting
Study to Evaluate LB-LR1109, Administered Alone for the Treatment of Solid Tumor and in Combination With Atezolizumab for the Treatment of NSCLC
NCT06332755Non-small Cell Lung Cancer(NSCLC), Head and Neck Squamous Cell Carcinoma(HNSCC), Renal Cell Carcinoma(RCC), Urothelial Carcinoma
LG Chem
Phase 1
76
Virginia
2024-06-05
Active, closed
A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
NCT06507306Solid Tumor, Adult
DrugsKQB198·Tagrisso·Amivantamab·Osimertinib
Kumquat Biosciences Inc.
Phase 1
92
Colorado, Florida, Michigan, New York, Ohio, Tennessee, Texas, Virginia
2024-06-03
Recruiting
Gleolan for Visualization of Newly Diagnosed or Recurrent Ovarian Cancer (OVA-302)
NCT05804370Ovarian Cancer
DrugGleolan
NX Development Corp
Phase 3
170
Arizona, Florida, Maryland, Minnesota, New York, Ohio, Pennsylvania, Virginia
2024-05-30
Active, closed
ELVN-002 With Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer
NCT06328738HER2-positive Breast Cancer, HER2-positive Gastric Cancer, HER2 Positive Solid Tumors, HER2 Amplification
DrugsELVN-002·Eribulin·Leucovorin·Trastuzumab
Enliven Therapeutics
Phase 1
275
Florida, Missouri, Virginia
2024-05-30
Active, closed
A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence
NCT06336291Glioblastoma
DrugsOnfekafusp alfa·Lomustine
Philogen S.p.A.
Phase 2
90
Illinois, Massachusetts, New York, Pennsylvania, Texas, Virginia
2024-05-22
Active, closed
Long Term Follow-up Study of Type-1 Gaucher Subjects Post FLT201 Dose (GALILEO-2)
NCT06545136Gaucher Disease, Type 1
Spur Therapeutics
Phase 1/2
75
Virginia
2024-05-13
Recruiting
Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors
NCT06425926Melanoma Stage IV, Solid Tumor
Georgiamune Inc
Phase 1/2
117
Arizona, California, Massachusetts, Montana, New York, Ohio, Tennessee, Virginia
2024-05-09
Recruiting
Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients
NCT05703971Small Cell Lung Cancer Extensive Stage
DrugsQuaratusugene ozeplasmid·Tecentriq·Atezolizumab
Genprex, Inc.
Phase 1/2
62
Colorado, Missouri, Ohio, Oregon, Texas, Virginia, Washington
2024-05-09
By invitation
Long Term Follow-up for RGX-202
NCT06491927Duchenne Muscular Dystrophy
REGENXBIO Inc.
Observational
66
Arkansas, California, Illinois, Texas, Virginia
2024-05-08
Recruiting
A Study of TSN1611 Treating Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation
NCT06385925Malignant Neoplasm
DrugsFluorouracil·Leucovorin·Oxaliplatin
Tyligand Pharmaceuticals (Suzhou) Limited
Phase 1/2
440
Texas, Virginia
2024-04-29
Recruiting
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
NCT06330064Recurrent or Metastatic Solid Tumors
DrugIfinatamab Deruxtecan
Daiichi Sankyo
Phase 1/2
680
California, Illinois, Minnesota, New York, Tennessee, Texas, Utah, Virginia
2024-04-10
Active, closed
Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Hernia Surgery (Enable Hernia Repair)
NCT06445504Inguinal Hernia, Ventral Hernia
Medtronic - MITG
Not applicable
206
Florida, Illinois, New York, North Carolina, Ohio, Texas, Virginia
2024-04-08
Active, closed
A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours
NCT06305247Melanoma, Head and Neck Squamous Cell Carcinoma, Pancreatic Ductal Adenocarcinoma, Colorectal Cancer
Ipsen
Phase 1/2
36
California, Connecticut, Tennessee, Virginia
2024-04-03
Recruiting
First In Human Study of CX-2051 in Advanced Solid Tumors
NCT06265688Solid Tumor, Adult
DrugsAvastin·Bevacizumab
CytomX Therapeutics
Phase 1
160
Colorado, Massachusetts, New York, North Carolina, Tennessee, Texas, Virginia
2024-04-02
Active, closed
OPtilume™ BPH Catheter SystEm for Treatment of Men eXperiencing Symptomatic BPH
NCT06560476Benign Prostatic Hyperplasia
Urotronic Inc.
Observational
500
Florida, Nebraska, Nevada, New York, Oregon, Texas, Virginia
2024-03-30
Active, closed
Safety and Efficacy Study of NUV-1511 in Adult Patients With Advanced Solid Tumors
NCT06334432Advanced Solid Tumor, HER2-negative Breast Cancer, Metastatic Castration-resistant Prostate Cancer (mCRPC), Pancreatic Cancer
Nuvation Bio Inc.
Phase 1/2
466
Michigan, New Jersey, New York, North Carolina, Texas, Utah, Virginia, Washington
2024-03-14
Recruiting
PAS-004 in Patients With Advanced Solid Tumors
NCT06299839RAS Mutation, NF1 Mutation, RAF Mutation, Advanced Solid Tumors
DrugPAS-004
Pasithea Therapeutics Corp.
Phase 1
48
Texas, Virginia
2024-02-29
Active, closed
First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer
NCT06239467Advanced Cancer, Breast Cancer, Advanced Solid Tumors, PI3K Gene Mutation
DrugsAtirmociclib·Tucatinib·Ribociclib·Fulvestrant
OnKure, Inc.
Phase 1
200
California, Colorado, Massachusetts, Nevada, New York, Tennessee, Virginia, Washington
2024-02-26
Recruiting
Phase I/II Study of SKG0106 Intravitreal Injection in Patients With Neovascular Age-related Macular Degeneration (nAMD)
NCT05986864Neovascular Age-related Macular Degeneration
Skyline Therapeutics (US) Inc.
Phase 1/2
68
Florida, Massachusetts, Texas, Virginia
2024-02-23
Active, closed
Study to Assess Neoadjuvant Durvalumab (D) and Platinum-Based Chemotherapy (CT), Followed by Either Surgery and Adjuvant D or CRT and Consolidation D, in Resectable or Borderline Resectable Stage IIB-IIIB NSCLC (MDT-BRIDGE)
NCT05925530Non-small Cell Lung Cancer
DrugDurvalumab
AstraZeneca
Phase 2
142
New York, Texas, Virginia
2024-02-22
Active, closed
A Phase 1/2 Study of VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)
NCT06185764Myotonic Dystrophy Type 1 (DM1)
DrugVX-670
Vertex Pharmaceuticals Incorporated
Phase 1/2
47
California, Florida, Kansas, Massachusetts, Missouri, North Carolina, Pennsylvania, Virginia
2024-02-20
Active, closed
DAREON™-9: A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With Small Cell Lung Cancer When Taken Together With a Single Agent Chemotherapy
NCT05990738Small Cell Lung Carcinoma (SCLC)
DrugsObrixtamig·Topotecan
Boehringer Ingelheim
Phase 1
69
District of Columbia, Florida, Virginia
2024-02-14
Recruiting
Evaluation of the Aortoseal™ for Sealing and Fixation of AAA Endovascular Grafts to Aortic Wall
NCT06586021Abdominal Aortic Aneurysm (AAA)
Endoron Medical
Not applicable
25
Virginia
2024-02-06
Recruiting
Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Subjects With Corneal Scars
NCT06257355Corneal Scar
DrugCSB-001 Ophthalmic
Claris Biotherapeutics, Inc.
Phase 1
20
California, Indiana, Minnesota, Oregon, Texas, Virginia
2024-02-05
Recruiting
Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms
NCT07853768Fracture Arm, Fracture Leg, Wrist Injury, Ankle Injury
Rivanna Medical, Inc.
Not applicable
25,000
California, Colorado, Connecticut, Texas, Utah, Virginia
2024-01-29
Recruiting
STIMIT Activator 1 IDE Study
NCT05883163Diaphragm Issues
Stimit AG
Not applicable
40
Connecticut, Massachusetts, Virginia
2024-01-24
Recruiting
A Study of NPX887 for Participants With Solid Tumors Known to Express B7-H7/HHLA2
NCT06240728Metastatic Malignant Neoplasm
NextPoint Therapeutics, Inc.
Phase 1
144
Maryland, Massachusetts, New York, Texas, Virginia
2024-01-22
Recruiting
A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation
NCT06059963Colorectal Cancer, Advanced Adenocarcinoma
Universal Diagnostics
Observational
12,000
Virginia
2024-01-18
Recruiting
A Study of AZD3470, a PRMT5 Inhibitor, Given as Monotherapy and in Combination in Patients With MTAP Deficient Advanced/Metastatic Solid Tumors
NCT06130553Advanced Solid Tumors That Are MTAP Deficient
DrugsAZD3470·Dato-DXd
AstraZeneca
Phase 1/2
334
California, Connecticut, Maryland, Oregon, Pennsylvania, Rhode Island, Virginia
2024-01-18
Active, closed
A Trial to Learn More About an Experimental Gene Therapy Called Bidridistrogene Xeboparvovec (SRP-9003) as a Possible Treatment for Limb Girdle Muscular Dystrophy 2E/R4
NCT06246513Limb-girdle Muscular Dystrophy
Sarepta Therapeutics, Inc.
Phase 3
17
California, Ohio, Pennsylvania, Virginia
2024-01-15
Recruiting
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
NCT06137118B-cell Acute Lymphoblastic Leukemia (B-ALL)
DrugSurovatamig
AstraZeneca
Phase 1/2
255
Alabama, California, Florida, Georgia, Illinois, New York, Texas, Virginia
2023-12-29
Recruiting
Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors
NCT05280314Melanoma, Squamous Cell Carcinoma of Head and Neck
DrugsIO102-IO103·Pembrolizumab KEYTRUDA
IO Biotech
Phase 2
60
Connecticut, Massachusetts, Virginia
2023-12-21
Recruiting
A Study of LM-24C5 For Advanced Solid Tumors
NCT06187402Advanced Solid Tumor
DrugLM-24C5
LaNova Medicines Limited
Phase 1/2
49
California, Florida, Indiana, Ohio, Texas, Virginia
2023-12-20
Recruiting
A Phase I/II, Open-label Study to Investigate the Safety, Tolerability, PK, and Preliminary Efficacy of FB849
NCT05761223Advanced Solid Tumor
DrugPembrolizumab
1ST Biotherapeutics, Inc.
Phase 1/2
151
Ohio, Texas, Virginia, Washington
2023-12-13
Recruiting
Safety and Tolerability Study of GIM-122 in Subjects With Advanced Solid Malignancies
NCT06028074Advanced Solid Malignancies
Georgiamune Inc
Phase 1/2
111
California, Florida, Kentucky, New Jersey, Tennessee, Texas, Virginia
2023-12-12
Recruiting
AZD0305 as Monotherapy or in Combination With Anticancer Agents in Participants With Multiple Myeloma
NCT06106945Multiple Myeloma
DrugsElranatamab·Pomalidomide·Dexamethasone
AstraZeneca
Phase 1/2
226
California, Georgia, Massachusetts, Michigan, Missouri, New York, Pennsylvania, Virginia
2023-12-05
Active, closed
A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced Cancer
NCT06005740Advanced Solid Tumor, Hepatocellular Carcinoma
TORL Biotherapeutics, LLC
Phase 1
70
Arizona, California, Florida, Minnesota, Virginia
2023-12-04
Active, closed
A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer
NCT06116786Carcinoma, Non-small-Cell Lung
DrugsJNJ-86974680·Cetrelimab
Johnson & Johnson Enterprise Innovation Inc.
Phase 1
67
Georgia, New Jersey, New York, Oregon, Pennsylvania, Virginia
2023-11-27
Recruiting
Safety and Effectiveness of the Yaari Extractor for Management of Shoulder Dystocia
NCT05913609Shoulder Dystocia
FetalEase Ltd.
Not applicable
80
Florida, Idaho, North Carolina, Virginia
2023-11-15
Recruiting
Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases
NCT06069570Carcinoma, Non-Small-Cell Lung Cancer, Bone Metastases From Solid Tumors
Kiromic BioPharma Inc.
Phase 1
48
Arizona, California, Pennsylvania, Texas, Virginia
2023-11-07
Recruiting
JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors
NCT06108050Advanced Solid Tumor, Metastatic Solid Tumor
DrugPembrolizumab
Jazz Pharmaceuticals
Phase 1
177
California, Colorado, Florida, North Carolina, Pennsylvania, Tennessee, Texas, Virginia
2023-11-07
Recruiting
MISHA Post-Market Clinical Study
NCT06118892Osteo Arthritis Knee
Moximed
Not applicable
120
California, North Carolina, Oregon, Virginia
2023-11-03
Recruiting
A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases
NCT06136884Solid Tumor Malignancies, Brain Metastases From Solid Tumors
A2A Pharmaceuticals Inc.
Phase 1
86
Michigan, Oklahoma, South Carolina, Texas, Virginia
2023-11-02
Active, closed
Gravitas Feeding Tube System Placement Validation in Neonates
NCT05914064Nasogastric Tube
Gravitas Medical, Inc.
Not applicable
100
California, Georgia, Massachusetts, Rhode Island, Virginia
2023-10-27
Recruiting
A Phase 1/2, First-in-Human Study On ODM-212 In Subjects With Selected Advanced Solid Tumours
NCT06725758Solid Tumours
DrugODM-212
Orion Corporation, Orion Pharma
Phase 1/2
315
California, Missouri, New York, Pennsylvania, Texas, Virginia
2023-10-26
Active, closed
A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Preliminary Anticancer Activity of GSK4524101 Alone or With Niraparib in Participants With Solid Tumors
NCT06077877Neoplasms
DrugNiraparib
GlaxoSmithKline
Phase 1/2
42
California, Missouri, Texas, Virginia
2023-10-24
Recruiting
A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agents
NCT06090266Cancer, Tumor, Solid, Malignant Neoplasm, Metastatic Cancer
DrugCemiplimab
OncoResponse, Inc.
Phase 1/2
168
Texas, Virginia
2023-10-24
Active, closed
Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study
NCT05868148Rotator Cuff Tears, Rheumatoid Arthritis Shoulder, Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus
Stryker Trauma and Extremities
Observational
200
California, Ohio, Texas, Virginia
2023-10-20
Recruiting
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
NCT06022029Triple Negative Breast Cancer, Diffuse Large B Cell Lymphoma, Follicular Lymphoma, Lymphoma, Non-Hodgkin
DrugCemiplimab
OncoNano Medicine, Inc.
Phase 1
168
California, Florida, Ohio, Pennsylvania, Texas, Virginia
2023-10-13
Recruiting
Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients
NCT04929236Pediatric Chronic Inflammatory Demyelinating Polyneuropathy
DrugPanzyga
Octapharma
Phase 3
30
Alabama, California, Kentucky, Pennsylvania, Texas, Virginia
2023-10-01
Recruiting
First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations
NCT06043817Non-Small Cell Lung Cancer, NSCLC, EGFR/HER2 Exon 20 Insertion Mutation
Pierre Fabre Medicament
Phase 1/2
345
California, North Carolina, Pennsylvania, Tennessee, Texas, Utah, Virginia
2023-09-26
Active, closed
Treatment of PAF With the Synaptic System
NCT05905835Paroxysmal Atrial Fibrillation
Synaptic Medical Corporation
Not applicable
128
Arizona, Arkansas, California, Missouri, New York, Tennessee, Texas, Virginia
2023-09-20
Active, closed
Venclose digiRF System Post Market Study
NCT05504070Venous Reflux, Chronic Venous Insufficiency
C. R. Bard
Not applicable
203
Colorado, Hawaii, Michigan, New Jersey, North Carolina, Texas, Virginia
2023-09-08
Recruiting
Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma
NCT05874414Cholangiocarcinoma
DrugTrametinib
Genfit
Phase 1/2
98
California, Florida, Illinois, New York, Pennsylvania, Texas, Virginia, Wisconsin
2023-08-21
Recruiting
Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
NCT05997615Hormone-refractory Prostate Cancer
Astellas Pharma Global Development, Inc.
Phase 1
437
California, Texas, Virginia, Washington
2023-08-10
Active, closed
4D-150 in Patients With Diabetic Macular Edema
NCT05930561Diabetic Macular Edema, Diabetic Retinopathy
DrugsAflibercept IVT·4D-150 IVT·Eylea
4D Molecular Therapeutics
Phase 2
72
Maryland, Oregon, Pennsylvania, Texas, Virginia
2023-08-09
Active, closed
Vepdegestrant (ARV-471/PF-07850327) + Palbociclib vs Letrozole + Palbociclib in ER(+)/HER2(-) Advanced Breast Cancer
NCT05909397Breast Cancer
DrugsVepdegestrant·Letrozole
Pfizer
Phase 3
59
Florida, Virginia
2023-08-09
Recruiting
A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors
NCT05954312Advanced Solid Tumors
DrugsDocetaxel·Paclitaxel·Pembrolizumab
Vividion Therapeutics, Inc.
Phase 1
290
Florida, Minnesota, Tennessee, Texas, Virginia
2023-07-28
Active, closed
Cemented vs Cementless Persona Keel RCT
NCT05630053Knee Pain Chronic, Rheumatoid Arthritis, Osteoarthritis, Traumatic Arthritis
Zimmer Biomet
Not applicable
300
Colorado, Illinois, Maryland, Oregon, Pennsylvania, Virginia
2023-07-25
Recruiting
A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib as a Single Agent or in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation
NCT05789082Non-Small Cell Lung Cancer
DrugsDivarasib·Pemetrexed·Cisplatin·Carboplatin
Hoffmann-La Roche
Phase 1/2
320
California, Connecticut, Florida, New York, Texas, Virginia
2023-06-20
Active, closed
NEUROMARK Registry Study
NCT05937308Chronic Rhinitis
Neurent Medical
Not applicable
150
Alabama, California, Florida, Kentucky, Texas, Utah, Virginia
2023-06-12
Recruiting
Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry
NCT05880537End-Stage Renal Disease
LifeNet Health
Observational
100
Alabama, California, Virginia
2023-06-06
Recruiting
A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors
NCT05948865Cancer, Cancer, Lung
DrugSYS6010
Conjupro Biotherapeutics, Inc.
Phase 1
132
California, Colorado, Florida, New Hampshire, Pennsylvania, Tennessee, Texas, Virginia
2023-06-06
Recruiting
Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture
NCT05883241Bone Fracture, Fresh Fracture
DrugDiclofenac
ZetrOZ, Inc.
Phase 1
90
Connecticut, Virginia
2023-06-01
Recruiting
A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer
NCT05930210Diabetic Foot Ulcer, Foot Ulcer, Diabetes Mellitus, Wound
Energenesis Biomedical Co., Ltd.
Phase 3
230
Florida, Georgia, Tennessee, Texas, Utah, Virginia
2023-05-30
Recruiting
A Study of DS-1103a Combination Therapy in Participants With Advanced Solid Tumors
NCT05765851Advanced Solid Tumor
DrugTrastuzumab deruxtecan
Daiichi Sankyo
Phase 1
108
Florida, Rhode Island, Utah, Virginia
2023-05-30
Recruiting
A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors
NCT05907980Solid Tumor
DrugsAtezolizumab·Pembrolizumab
Chugai Pharmaceutical
Phase 1
209
Pennsylvania, Rhode Island, Tennessee, Texas, Virginia
2023-05-24
Active, closed
Premedication to Reduce Amivantamab Associated Infusion Related Reactions
NCT05663866Carcinoma, Non-Small-Cell Lung
DrugsMontelukast·Lazertinib·Amivantamab·Methotrexate
Janssen Research & Development, LLC
Phase 2
68
California, Virginia, Washington
2023-05-18
Active, closed
A Study of Combination Therapy With Amivantamab and Cetrelimab in Participants With Metastatic Non-small Cell Lung Cancer
NCT05908734Carcinoma, Non-Small-Cell Lung
DrugsCetrelimab·Amivantamab
Janssen Research & Development, LLC
Phase 1/2
71
California, Oregon, Texas, Virginia
2023-05-18
Active, closed
A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)
NCT05230459Limb Girdle Muscular Dystrophy, Limb-Girdle Muscular Dystrophy Type 2, LGMD2I, Muscular Dystrophy
AskBio Inc
Phase 1/2
9
California, Iowa, Kansas, Maryland, Virginia, Washington
2023-05-15
Active, closed
A Study to Evaluate ATP150/ATP152/ATP162, VSV-GP154 and Ezabenlimab in Patients With Pancreatic Ductal Adenocarcinoma
NCT05846516Pancreatic Ductal Adenocarcinoma
DrugEzabenlimab
Boehringer Ingelheim
Phase 1
59
California, Colorado, Florida, Michigan, New York, Ohio, Texas, Virginia
2023-05-11
Active, closed
A Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
NCT05789069Renal Cell Carcinoma, Melanoma, Non Small Cell Lung Cancer, Gastric Cancer
DrugTislelizumab
HiFiBiO Therapeutics
Phase 1
83
California, Pennsylvania, Virginia
2023-05-09
By invitation
The Use of the LuViva Advanced Cervical Scan to Identify Women at High-Risk for Cervical Neoplasia
NCT04915495Cervical Dysplasia
Guided Therapeutics
Not applicable
400
Alabama, Georgia, Michigan, Virginia
2023-05-05
Recruiting
A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes
NCT05732103Acute Myeloid Leukemia, Myelodysplastic Syndromes
Chordia Therapeutics, Inc.
Phase 1/2
225
Arizona, Florida, Illinois, Minnesota, New York, Texas, Virginia, Washington
2023-04-25
Active, closed
A Trial to Learn How the Cancer Vaccine BNT116 in Combination With Cemiplimab Works and How Safe the Combination is in Adults With Advanced Non-small Cell Lung Cancer (EMPOWERVAX Lung 1)
NCT05557591Advanced Non-Small Cell Lung Cancer
DrugsBNT116·Cemiplimab
Regeneron Pharmaceuticals
Phase 2
51
California, Kentucky, New Mexico, New York, North Carolina, Texas, Virginia, Washington
2023-04-21
Active, closed
A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal Cancer
NCT05723562Neoplasms, Rectal
DrugDostarlimab
GlaxoSmithKline
Phase 2
154
California, New Mexico, New York, Pennsylvania, Tennessee, Texas, Virginia
2023-04-03
Recruiting
Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
NCT05856981Solid Tumor, Adult, Metastatic Solid Tumor, Refractory Cancer, CRC, Colorectal Cancer
DrugsKeytruda·Pembrolizumab
Sairopa B.V.
Phase 1
130
Michigan, Missouri, Ohio, Virginia
2023-04-03
Active, closed
Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors
NCT05704985Cancer, Solid Tumor, Colorectal Cancer, Pancreas Cancer
DrugsEGFR·Nivolumab·Pembrolizumab
DEKA Biosciences
Phase 1
39
California, New York, Oklahoma, Texas, Virginia
2023-04-03
Active, closed
A Study to Evaluate the Efficacy and Safety of Obinutuzumab Versus MMF in Participants With Childhood Onset Idiopathic Nephrotic Syndrome
NCT05627557Childhood Idiopathic Nephrotic Syndrome
DrugsAcetaminophen/paracetamol·Diphenhydramine hydrochloride·Methylprednisolone·Obinutuzumab
Hoffmann-La Roche
Phase 3
85
California, Florida, Georgia, New Jersey, North Carolina, Utah, Virginia
2023-03-29
Active, closed
ELVN-002 in HER2 Mutant Non-Small Cell Lung Cancer
NCT05650879HER2 Mutant Non-small Cell Lung Cancer, HER2-positive Metastatic Breast Cancer, HER2 Gene Mutation, HER2 Amplification
DrugsELVN-002·Fam-Trastuzumab Deruxtecan-Nxki·Ado-trastuzumab emtansine·Trastuzumab emtansine
Enliven Therapeutics
Phase 1
198
Colorado, Florida, Massachusetts, Virginia
2023-03-20
Active, closed
Prospective Case Registry for Wounds
NCT05898698Wound Healing Delayed
Kerecis Ltd.
Observational
300
Virginia
2023-03-17
Recruiting
A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma
NCT05456256Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung
DrugsParaplatin·Pemetrexed·Carboplatin
Lantern Pharma Inc.
Phase 2
90
California, Pennsylvania, Texas, Virginia
2023-03-01
Active, closed
Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term Application
NCT05094089Hernia, Ventral, Hernia Incisional, Hernia Incisional Ventral
W.L.Gore & Associates
Observational
320
Georgia, Massachusetts, Michigan, New Mexico, New York, North Carolina, South Carolina, Virginia
2023-02-24
Active, closed
Study With Various Immunotherapy Treatments in Participants With Lung Cancer
NCT05676931Advanced Non-Small Cell Lung Cancer
DrugsQuemliclustat·Domvanalimab·Zimberelimab·Docetaxel
Gilead Sciences
Phase 2
400
Alabama, California, Florida, Illinois, Louisiana, Michigan, Virginia, Washington
2023-02-21
Recruiting
A Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer
NCT05683418HR+/HER2-negative Breast Cancer
DrugsRibociclib·Palbociclib·Fulvestrant
Totus Medicines
Phase 1
241
Illinois, Massachusetts, Nevada, Pennsylvania, Tennessee, Texas, Virginia
2023-02-15
Active, closed
SKB264 in Combination With Pembrolizumab in Subjects With Selected Solid Tumors
NCT05642780Solid Tumor
DrugsSacituzumab tirumotecan·Keytruda·Pembrolizumab
Klus Pharma Inc.
Phase 2
240
Indiana, Kentucky, Maryland, Minnesota, New York, Texas, Virginia
2023-01-17
Recruiting
Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer
NCT05573126Hormone Receptor-positive Breast Cancer, Hormone Receptor Positive HER-2 Negative Breast Cancer, Metastatic Breast Cancer
DrugsElacestrant·Exemestane·Everolimus·Abemaciclib
Ellipses Pharma
Phase 1/2
95
Connecticut, Florida, Massachusetts, Michigan, Tennessee, Texas, Virginia
2023-01-11
Active, closed
Study of AC699 in Patients With Estrogen Receptor Positive/Human Epidermal Growth Factor Receptor 2 Negative (ER+/HER2-) Locally Advanced or Metastatic Breast Cancer
NCT05654532Breast Cancer
Accutar Biotechnology Inc
Phase 1
100
Colorado, Florida, Maryland, Tennessee, Texas, Virginia, Washington
2022-12-29
Active, closed
A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED)
NCT05487599Gaucher Disease, Gaucher Disease, Type 1
Prevail Therapeutics
Phase 1/2
8
North Carolina, Virginia
2022-12-20
Active, closed
A Study of YL202 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer and Breast Cancer
NCT05653752Non Small Cell Lung Cancer, Breast Cancer
DrugYL202
MediLink Therapeutics (Suzhou) Co., Ltd.
Phase 1
80
Florida, Michigan, Texas, Virginia, Washington
2022-12-20
Active, closed
Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials
NCT05335876Spinal Muscular Atrophy (SMA)
DrugZolgensma
Novartis Pharmaceuticals
Phase 3
20
Virginia
2022-12-19
Active, closed
A Study to Compare the Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care (BSC) Versus Placebo Plus BSC in Participants With International Prognostic Scoring System Revised (IPSS-R) Low- or Intermediate-risk Myelodysplastic Syndrome (MDS)
NCT05469737Myelodysplastic Syndromes
DrugAzacitidine
Bristol-Myers Squibb
Phase 2/3
230
Florida, New York, Pennsylvania, Texas, Virginia
2022-12-14
Active, closed
A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer
NCT05488314Carcinoma, Non-Small-Cell Lung
DrugsCapmatinib·Amivantamab
Janssen Research & Development, LLC
Phase 1/2
57
Alabama, California, New York, Virginia
2022-12-13
Active, closed
A Study of DZD9008 Versus Platinum-Based Doublet Chemotherapy in Local Advanced or Metastatic Non-small Cell Lung Cancer (WU-KONG28)
NCT05668988Non-small Cell Lung Cancer
DrugsSunvozertinib·Pemetrexed·Carboplatin
Dizal Pharmaceuticals
Phase 3
324
California, Colorado, Florida, New York, Ohio, Oregon, Texas, Virginia
2022-12-13
Active, closed
Study of the Monoclonal Antibody IMT-009 in Patients With Advanced Solid Tumors or Lymphomas
NCT05565417Non Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Triple Negative Breast Cancer, Cutaneous Squamous Cell Carcinoma
Immunitas Therapeutics
Phase 1/2
67
Arizona, Colorado, Florida, Oklahoma, Oregon, Tennessee, Texas, Virginia
2022-11-28
Active, closed
PRCT001 Aquablation theraPy Outcomes in pRostate Cancer patienTs
NCT06051942Benign Prostatic Hyperplasia, Localized Prostate Cancer
PROCEPT BioRobotics
Not applicable
125
California, Illinois, Virginia
2022-11-22
Active, closed
A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP)
NCT05456191Philadelphia Chromosome-Positive Chronic Myeloid Leukemia
DrugsAsciminib·ABL001·Nilotinib
Novartis Pharmaceuticals
Phase 3
568
Colorado, Illinois, Minnesota, North Carolina, Ohio, Oregon, Texas, Virginia
2022-11-21
Active, closed
Implantation of BioSphincter TM for Treatment of Severe Passive Fecal Incontinence
NCT05616208Fecal Incontinence
Cellf Bio LLC
Phase 1
10
Virginia
2022-11-02
Active, closed
A Study to Evaluate Migalastat in Fabry Subjects With Amenable GLA Variant and Renal Disease
NCT04020055Fabry Disease
DrugMigalastat HCl
Amicus Therapeutics
Phase 3
14
Georgia, Ohio, Virginia
2022-10-31
Recruiting
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
NCT05208762Carcinoma, Non-Small-Cell Lung, Squamous Cell Carcinoma of the Head and Neck, Esophageal Squamous Cell Carcinoma, Triple Negative Breast Neoplasms
DrugsPF-08046054·Keytruda·Pembrolizumab
Seagen, a wholly owned subsidiary of Pfizer
Phase 1
714
Alabama, California, Iowa, Michigan, Ohio, Texas, Utah, Virginia
2022-10-25
Active, closed
The GORE® VIABAHN® FORTEGRA Venous Stent IVC Study
NCT05409976Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis
W.L.Gore & Associates
Not applicable
136
California, District of Columbia, Illinois, Michigan, New York, North Carolina, Virginia
2022-10-25
Active, closed
A Study of NX-019 in Patients with Advanced, Epidermal Growth Factor Receptor (EGFR) Mutant Cancer
NCT05514496EGFR Mutation-Related Tumors
Nalo Therapeutics Inc.
Phase 1
258
California, Minnesota, Virginia
2022-10-05
Active, closed
Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1
NCT05481879Myotonic Dystrophy Type 1 (DM1)
DrugZeleciment basivarsen
Dyne Therapeutics
Phase 1/2
127
California, Florida, Indiana, Iowa, Missouri, New York, Texas, Virginia
2022-09-05
Active, closed
A Study of BPM31510 With Vitamin K1 in Subjects With Newly Diagnosed Glioblastoma (GB)
NCT04752813Glioblastoma, Glioblastoma Multiforme
DrugTemozolomide
BPGbio
Phase 2
50
California, Massachusetts, New Jersey, New York, Texas, Virginia
2022-08-22
By invitation
Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis
NCT05374590Generalized Myasthenia Gravis, gMG
DrugsEfgartigimod PH20·Efgartigimod
argenx
Phase 2/3
12
Illinois, North Carolina, Virginia
2022-08-18
Recruiting
Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets
NCT05317858Brain Tumor, Non Small Cell Lung Cancer
DrugsCemiplimab·Tecentriq·Atezolizumab·Nivolumab
InSightec
Phase 3
30
Arizona, California, Florida, Maryland, North Carolina, Oregon, Rhode Island, Virginia
2022-08-12
Recruiting
Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)
NCT05431270Non Small Cell Lung Cancer, Pancreatic Ductal Adenocarcinoma
DrugsNab-paclitaxel·Pemetrexed·Tislelizumab·Docetaxel
Phanes Therapeutics
Phase 1/2
40
North Carolina, Oklahoma, Tennessee, Texas, Virginia
2022-08-11
Active, closed
A Clinical Study Evaluating a Combination of Oregovomab and Niraparib in Adult Women With Platinum Sensitive Recurrent Ovarian Cancer.
NCT05335993Recurrent Ovarian Cancer, Recurrent Epithelial Cancer of Ovary, Recurrent Epithelial Ovarian Cancer, Recurrent Fallopian Tube Cancer
DrugsOregovomab·Niraparib
CanariaBio Inc.
Phase 2
10
North Carolina, Oklahoma, Virginia
2022-07-25
Recruiting
A Study to Evaluate PEEL-224 in Patients With Advanced Solid Tumors
NCT05329103Advanced Solid Tumor
Peel Therapeutics Inc
Phase 1
65
Arizona, California, North Carolina, Pennsylvania, Rhode Island, Texas, Utah, Virginia
2022-07-11
Active, closed
PDN Post Market, Multicenter, Prospective, Global Clinical Study
NCT05301816Diabetic Neuropathy, Painful
Nevro Corp
Not applicable
497
Alaska, Michigan, Ohio, Oklahoma, Oregon, Pennsylvania, Virginia
2022-07-05
Active, closed
Expander-2 Trial: Randomized Study to Evaluate Safety & Efficacy of the Urocross® Expander System & Retrieval Sheath
NCT05400980Benign Prostatic Hyperplasia
Prodeon Medical, Inc
Not applicable
240
Illinois, Virginia
2022-07-05
Active, closed
Study of Furmonertinib in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Activating, Including Uncommon, Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Mutations
NCT05364073Non-Small Cell Lung Cancer (NSCLC), Metastatic Non-Small Cell Lung Cancer, Advanced Non-Small Cell Lung Cancer, HER2 Exon 20 Mutations
DrugFurmonertinib
ArriVent BioPharma, Inc.
Phase 1
160
Arizona, California, Florida, Michigan, Texas, Virginia
2022-06-30
Active, closed
A Trial to Assess the Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With PLD
NCT05281328Polycystic Liver Disease
DrugCAM2029
Camurus AB
Phase 2/3
71
Minnesota, New York, Pennsylvania, Texas, Virginia
2022-06-28
Active, closed
A Study of AK112 With or Without AK117 in Metastatic Colorectal Cancer
NCT05382442Metastatic Colorectal Cancer
DrugsLigufalimab·Ivonescimab·Leucovorin·Irinotecan
Akeso
Phase 2
254
California, Virginia
2022-06-27
Recruiting
Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies
NCT05417594Advanced Solid Malignancies
DrugsPalacaparib·Dato-DXd·Trastuzumab deruxtecan·Temozolomide
AstraZeneca
Phase 1/2
695
California, Illinois, Massachusetts, New York, Oregon, Texas, Virginia
2022-06-24
Recruiting
Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer
NCT05142189Non-Small Cell Lung Cancer
DrugsBNT116·Gotistobart·Cemiplimab·Osimertinib
BioNTech SE
Phase 1
320
Kentucky, Maryland, Ohio, Texas, Virginia
2022-06-17
Active, closed
ProVee Urethral Expander System IDE Study (ProVIDE)
NCT05186740BPH With Symptomatic Lower Urinary Tract Symptoms
ProVerum Medical
Not applicable
221
California, Florida, Illinois, Nevada, New York, North Carolina, Texas, Virginia
2022-06-09
Active, closed
CFI-402257, a Potent and Selective TTK Inhibitor, in Solid Tumors and With Fulvestrant in Breast Cancer
NCT05251714Advanced Solid Tumor, Breast Cancer
DrugsCFI-402257·Fulvestrant
Treadwell Therapeutics, Inc
Phase 1/2
44
Ohio, Texas, Utah, Virginia
2022-05-27
Active, closed
Clinical Feasibility Study to Evaluate the Safety and Performance of the Profound Matrix System
NCT06157567Skin Laxity, Wrinkle, Skin Condition
Candela Corporation
Not applicable
500
Florida, Massachusetts, North Carolina, Virginia
2022-05-24
Active, closed
IO102-IO103 in Combination With Pembrolizumab Versus Pembrolizumab Alone in Advanced Melanoma (IOB-013 / KN-D18)
NCT05155254Metastatic Melanoma, Unresectable Melanoma
DrugsIO102-IO103·Pembrolizumab
IO Biotech
Phase 3
407
Florida, New York, Virginia
2022-05-17
Active, closed
RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)
NCT05134012Coronary Artery Disease
MedTrace Pharma A/S
Phase 3
215
Iowa, Minnesota, Missouri, Pennsylvania, Texas, Virginia
2022-05-08
Active, closed
A Study to Evaluate the Effect of Venglustat Tablets on Left Ventricular Mass Index in Male and Female Adult Participants With Fabry Disease
NCT05280548Fabry Disease
DrugsAgalsidase beta·Replagal·Venglustat·Migalastat HCl
Sanofi
Phase 3
104
Alabama, California, Georgia, Illinois, New York, Texas, Utah, Virginia
2022-05-03
Active, closed
US Pilot Study of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus
NCT05232838Hydrocephalus, Normal Pressure, Hydrocephalus
CereVasc Inc
Not applicable
50
Connecticut, Florida, Kansas, Kentucky, Massachusetts, New York, Rhode Island, Virginia
2022-04-20
Active, closed
Study to Evaluate the Efficacy and Safety of Venglustat in Adult and Pediatric Patients With Gaucher Disease Type 3
NCT05222906Gaucher's Disease Type III
DrugsImiglucerase·Venglustat
Sanofi
Phase 3
43
Connecticut, Iowa, Texas, Virginia
2022-04-18
Active, closed
A Phase I Study, Evaluating the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors
NCT05159700Advanced Solid Tumor, Advanced Solid Malignancies
DrugPRJ1-3024
Zhuhai Yufan Biotechnologies Co., Ltd
Phase 1
39
Colorado, Florida, Ohio, Texas, Virginia
2022-03-31
Recruiting
A Study in Patients With Advanced Cancers
NCT05320588Advanced Cancer, Advanced Solid Tumor, Cancer, Oncology
DrugsKeytruda·Pembrolizumab
BiOneCure Therapeutics Inc.
Phase 1/2
332
Texas, Virginia
2022-03-25
Active, closed
A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
NCT05238883Gastric Cancer, Renal Cell Carcinoma, Melanoma, Sarcoma
DrugTislelizumab
HiFiBiO Therapeutics
Phase 1
72
Arizona, California, Florida, Minnesota, Missouri, Texas, Virginia
2022-03-10
Active, closed
Cardiac Implantable Electronic Device (CIED) Research Study
NCT05061862Arrhythmias, Cardiac, Bradycardia, Tachycardia
Medtronic Cardiac Rhythm and Heart Failure
Observational
1,000
Florida, Georgia, Oregon, Pennsylvania, Virginia
2022-03-06
Recruiting
Trisol System EFS Study
NCT04905017Tricuspid Regurgitation
Trisol Medical
Not applicable
30
California, Georgia, New York, Ohio, Pennsylvania, Tennessee, Virginia
2022-03-02
Recruiting
MTX-001 for the Treatment of Non-Healing Venous Stasis Ulcers
NCT04647240Venous Stasis Ulcer, Venous Leg Ulcer
Merakris Therapeutics
Phase 2
80
Arizona, California, Florida, Louisiana, New York, Ohio, Texas, Virginia
2022-02-26
Active, closed
Study to Evaluate Efficacy & Safety of Afuresertib Plus Fulvestrant in Patients With Locally Advanced or Metastatic HR+/HER2- Breast Cancer
NCT04851613Breast Cancer
DrugFulvestrant
Laekna Limited
Phase 3
256
California, Georgia, Iowa, Mississippi, Vermont, Virginia
2022-02-18
Recruiting
US Post-Market Surveillance Study of the Surfacer System
NCT05050799Venous Disease
Merit Medical Systems, Inc.
Observational
30
Arizona, Florida, Georgia, Ohio, Texas, Utah, Virginia
2022-02-08
Active, closed
Tumor-induced Osteomalacia Disease Monitoring Program
NCT04783428Tumor-induced Osteomalacia (TIO)
Ultragenyx Pharmaceutical Inc
Observational
23
Connecticut, Indiana, Maryland, Tennessee, Virginia
2022-01-31
Active, closed
Kerecis Case Registry for SurgiBind : Soft Tissue Reinforcement
NCT05898711Surgery-Complications
Kerecis Ltd.
Observational
200
Virginia
2022-01-27
Active, closed
Pharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PN
NCT05309668Neurofibromatosis Type 1
DrugSelumetinib
AstraZeneca
Phase 1/2
36
Ohio, Pennsylvania, Texas, Virginia
2022-01-21
Active, closed
A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)
NCT05002127Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Gastric Adenocarcinoma
DrugsEvorpacept·Ramucirumab·Herceptin·Taxol
ALX Oncology Inc.
Phase 2/3
127
California, Tennessee, Virginia, Washington
2022-01-15
Active, closed
A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies
NCT05199272Solid Tumor, Clear Cell Renal Cell Carcinoma, Epithelial Ovarian Cancer, Fallopian Tube Cancer
23andMe, Inc.
Phase 1/2
141
California, Georgia, Michigan, New York, Oregon, Tennessee, Texas, Virginia
2021-12-29
Recruiting
A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)
NCT05067283Advanced Solid Tumors
DrugsCalderasib·Leucovorin·Cetuximab·Adrucil
Merck Sharp & Dohme LLC
Phase 1
830
Florida, Michigan, New Jersey, New York, Virginia, Wisconsin
2021-12-17
Active, closed
A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations
NCT05163028Non Small Cell Lung Cancer, Colorectal Cancer, Pancreatic Cancer, Solid Tumor
HUYABIO International, LLC.
Phase 1
42
California, Florida, Ohio, Texas, Virginia
2021-12-13
Active, closed
RCT, Blinded, 2-Arm Efficacy Study of IP and Placebo in Patients With Chronic Pain Related to Osteoarthritis of the Knee
NCT05318521Degenerative Arthritis
DrugIbuprofen
Overseas Pharmaceuticals, Ltd.
Phase 3
500
California, Florida, South Carolina, Virginia
2021-12-10
Active, closed
Head and Intraocular Trauma Tool for the Identification of Mild Traumatic Brain Injury
NCT05092295Brain Injuries, Traumatic
Rebiscan, Inc.
Observational
200
Virginia
2021-12-01
Recruiting
Pediatric Post-Approval Registry
NCT04457154Obstructive Sleep Apnea
Inspire Medical Systems, Inc.
Observational
60
Colorado, Georgia, North Carolina, Ohio, Pennsylvania, Texas, Virginia
2021-11-30
Recruiting
First in Human Study of TORL-1-23 in Participants With Advanced Cancer
NCT05103683Advanced Solid Tumor, Ovarian Cancer, Endometrial Cancer, NSCLC
DrugTORL-1-23
TORL Biotherapeutics, LLC
Phase 1
90
California, Kentucky, Minnesota, New York, Ohio, Texas, Virginia
2021-11-17
Active, closed
Study BT7480-100 in Patients With Advanced Malignancies Associated With Nectin-4 Expression
NCT05163041Advanced Solid Tumor
DrugNivolumab
BicycleTx Limited
Phase 1/2
200
Iowa, New York, Ohio, Pennsylvania, Texas, Virginia
2021-11-02
Recruiting
Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod Administered Intravenously in Children With Generalized Myasthenia Gravis
NCT04833894Generalized Myasthenia Gravis
DrugEfgartigimod
argenx
Phase 2/3
12
Illinois, North Carolina, Virginia
2021-10-26
Active, closed
Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP)
NCT05082454Aortic Valve Disease
JOTEC GmbH
Observational
108
Pennsylvania, Texas, Virginia
2021-10-20
Active, closed
A Long-term Extension Study of Ustekinumab in Pediatric Participants
NCT05092269Crohn Disease, Colitis, Ulcerative, Arthritis, Psoriatic
DrugUstekinumab
Janssen Research & Development, LLC
Phase 3
159
Georgia, New York, North Carolina, Virginia
2021-10-18
Active, closed
A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors
NCT04931342Ovarian Cancer
DrugsCobimetinib·Ipatasertib·Giredestrant·Inavolisib
Hoffmann-La Roche
Phase 2
176
California, Missouri, North Carolina, Ohio, Oklahoma, Texas, Virginia, Washington
2021-10-07
Recruiting
A Study of NX-1607 in Adults With Advanced Malignancies
NCT05107674Ovarian Cancer, Epithelial, Gastric Cancer, GastroEsophageal Junction (GEJ) Cancer, Head and Neck Squamous Cell Carcinoma
DrugPaclitaxel
Nurix Therapeutics, Inc.
Phase 1
345
California, Colorado, Illinois, North Carolina, Oklahoma, Texas, Virginia, Washington
2021-09-29
Recruiting
First in Human, Dose Escalation Study of AN4005
NCT04999384Advanced Solid Tumor, Advanced Lymphoma
Adlai Nortye Biopharma Co., Ltd.
Phase 1
31
New Jersey, New York, South Carolina, Virginia
2021-09-27
Active, closed
A Multi-Center Post-Market Data Collection Protocol to Evaluate the Performance of Orthofix Spine Devices
NCT05082090Spinal Disorders/Injuries
Orthofix Inc.
Observational
2,000
California, Louisiana, Mississippi, North Carolina, Rhode Island, Utah, Virginia
2021-09-15
Active, closed
A Study of AZD2936 Anti-TIGIT/Anti-PD-1 Bispecific Antibody in Participants With Advanced or Metastatic NSCLC
NCT04995523Non-Small-Cell Lung Carcinoma
DrugRilvegostomig
AstraZeneca
Phase 1/2
212
Illinois, Minnesota, Virginia
2021-09-14
Active, closed
Study of Selinexor Plus DRd for Newly Diagnosed Multiple Myeloma
NCT04782687Multiple Myeloma, Myeloma Multiple, Kahler Disease, Myeloma, Plasma Cell
DrugsDarzalex·Selinexor·Daratumumab·Lenalidomide
US Oncology Research
Phase 2
73
Arizona, Colorado, Maryland, New York, Oregon, Texas, Virginia
2021-09-10
Recruiting
Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy
NCT05004129Congenital Myotonic Dystrophy
DrugTideglusib
AMO Pharma Limited
Phase 2/3
76
Arkansas, California, Illinois, Iowa, New York, Pennsylvania, Utah, Virginia
2021-08-23
Active, closed
Long-Term Follow-up of Subjects Who Were Treated With ST-920
NCT05039866Fabry Disease, Fabry Disease, Cardiac Variant
Sangamo Therapeutics
Observational
32
California, Florida, Georgia, Iowa, Minnesota, New York, Ohio, Virginia
2021-08-16
Active, closed
Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE)
NCT04411654Gaucher Disease, Type 2
DrugsSirolimus·Methylprednisolone·Prednisone
Prevail Therapeutics
Phase 1/2
7
California, Minnesota, New York, Pennsylvania, Virginia
2021-06-29
Active, closed
Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea
NCT04801771Down Syndrome, Obstructive Sleep Apnea
Inspire Medical Systems, Inc.
Not applicable
57
Georgia, Massachusetts, Ohio, Pennsylvania, Texas, Virginia, Wisconsin
2021-06-24
Active, closed
Long-term Use of Viltolarsen in Boys With Duchenne Muscular Dystrophy in Clinical Practice (VILT-502)
NCT04687020Duchenne Muscular Dystrophy
NS Pharma, Inc.
Phase 4
9
California, Illinois, North Carolina, Virginia
2021-06-10
Recruiting
Safety, Efficacy, & Use of ViviGen Cellular Bone Matrix Allograft in Orthopaedic Fracture Care
NCT04299022Fractures, Bone, Nonunion of Fracture, Fractures, Open, Fractures, Ununited
LifeNet Health
Observational
250
Florida, New Jersey, North Carolina, Virginia
2021-06-01
Active, closed
Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination
NCT04868877Non-Small Cell Lung Cancer Metastatic, Gastric Cancer, Esophageal Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma
DrugsBispecific·Tagrisso·Osimertinib
Merus B.V.
Phase 1/2
194
California, Tennessee, Utah, Virginia
2021-04-28
Recruiting
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
NCT04786262Diabetes Mellitus, Type 1, Impaired Hypoglycemic Awareness, Severe Hypoglycemia
DrugZimislecel
Vertex Pharmaceuticals Incorporated
Phase 3
57
California, Florida, Illinois, Maryland, Massachusetts, Pennsylvania, Texas, Virginia
2021-03-29
Recruiting
Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors
NCT04665206Solid Tumor, Adult, Mesothelioma, NSCLC
DrugsPemetrexed/Carboplatin·Osimertinib·Ipilimumab
Vivace Therapeutics, Inc
Phase 1/2
434
California, Illinois, Massachusetts, Minnesota, New York, Texas, Virginia
2021-03-24
Recruiting
Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC
NCT04686305Locally Advanced or Metastatic Non-Small Cell Lung Cancer
DrugsVolrustomig·Rilvegostomig·Trastuzumab deruxtecan·Durvalumab
AstraZeneca
Phase 1
304
California, Kansas, Maryland, Michigan, New York, Texas, Virginia, Washington
2021-03-09
Active, closed
A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer
NCT04486378Colorectal Cancer Stage II, Colorectal Cancer Stage III
DrugAutogene cevumeran
BioNTech SE
Phase 2
327
California, Indiana, Minnesota, Ohio, Rhode Island, Tennessee, Texas, Virginia
2021-03-08
Active, closed
Study of Intravenous (IV) ABBV-637 Alone or in Combination With IV Docetaxel/Osimertinib to Assess Adverse Events and Change in Disease Activity in Adult Participants With Relapsed/Refractory (R/R) Solid Tumors
NCT04721015Advanced Solid Tumors Cancer, Non Small Cell Lung Cancer (NSCLC)
DrugsOsimertinib·Docetaxel
AbbVie
Phase 1
81
Massachusetts, Missouri, North Carolina, Rhode Island, Texas, Virginia
2021-02-23
Active, closed
Study of BBP-418 in Patients With LGMD2I
NCT04800874LGMD2I
DrugRibitol
ML Bio Solutions, Inc.
Phase 2
14
Virginia
2021-02-18
Recruiting
PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches
NCT04545502Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection
Vascutek Ltd.
Observational
2,000
Colorado, Florida, Indiana, North Carolina, Ohio, Pennsylvania, Virginia
2021-02-17
Active, closed
Study Evaluating Effectiveness and Safety of Zimberelimab and Domvanalimab in Lung Cancer
NCT04736173Non Small Cell Lung Cancer, Nonsquamous Non Small Cell Lung Cancer, Squamous Non Small Cell Lung Cancer, Lung Cancer
DrugsDomvanalimab·Zimberelimab·Pemetrexed·Paclitaxel
Arcus Biosciences, Inc.
Phase 2
169
Georgia, Texas, Virginia
2021-02-08
Active, closed
Phase 1b Study of Dato-DXd in Combination With Immunotherapy With or Without Carboplatin in Advanced or Metastatic Non-Small Cell Lung Cancer
NCT04612751Advanced or Metastatic NSCLC
DrugsSabestomig·Volrustomig·Rilvegostomig·Dato-DXd
AstraZeneca
Phase 1
155
California, Missouri, New Jersey, Ohio, Pennsylvania, Texas, Virginia
2021-02-02
Recruiting
Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
NCT03127267Amyotrophic Lateral Sclerosis
DrugsMasitinib·Riluzole
AB Science
Phase 3
495
Alabama, California, Kentucky, Maryland, Massachusetts, Virginia
2021-02-02
Active, closed
A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations
NCT04639219Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
DrugTrastuzumab deruxtecan
AstraZeneca
Phase 2
102
California, Indiana, Massachusetts, New Jersey, New York, Texas, Virginia
2020-12-30
Active, closed
A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer
NCT04538742Metastatic Breast Cancer
DrugsTucatinib·Pertuzumab·Trastuzumab deruxtecan·Durvalumab
AstraZeneca
Phase 1/2
245
Florida, New York, Ohio, Tennessee, Texas, Virginia
2020-12-28
Active, closed
Study of Immune Globulin Intravenous (Human) GC5107 in Pediatric Subjects With Primary Humoral Immunodeficiency
NCT04565015Primary Immune Deficiency
GC Biopharma Corp
Phase 3
24
Colorado, Texas, Virginia
2020-12-21
Active, closed
A Study of Osimertinib With or Without Chemotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer
NCT04351555Non-Small Cell Lung Cancer
DrugsTagrisso·Osimertinib·Pemetrexed·Cisplatin
AstraZeneca
Phase 3
358
California, Massachusetts, New Hampshire, New York, Texas, Virginia, Washington
2020-12-16
Recruiting
Evaluate the Continued Safety and Performance of the Foot and Ankle Products
NCT04715139Hyperpronated Foot, Reconstruction Surgeries of the Foot, Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle, Fixation of Small Bone Fragments of the Foot/Ankle
Arthrex, Inc.
Observational
700
California, Illinois, Tennessee, Texas, Virginia
2020-12-01
Active, closed
Study of Durvalumab Versus Placebo in Combination With Definitive Chemoradiation Therapy in Patient With ESCC
NCT04550260Esophageal Squamous Cell Carcinoma
DrugsFluorouracil·Durvalumab·Capecitabine·Cisplatin
AstraZeneca
Phase 3
640
Georgia, Kentucky, Texas, Virginia, West Virginia
2020-10-19
Active, closed
Less Frequent IV Dosing & Tumor Microenvironment (TME) Study of Nemvaleukin Alfa (ALKS 4230) Monotherapy and in Combination With Pembrolizumab (ARTISTRY-3)
NCT04592653Advanced Solid Tumor
DrugsKeytruda·Pembrolizumab
Mural Oncology, Inc
Phase 1/2
78
Michigan, Texas, Utah, Virginia
2020-09-30
Recruiting
A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors
NCT04370587Solid Tumor, Melanoma, HNSCC, Sarcoma
DrugT3011
ImmVira Pharma Co. Ltd
Phase 1/2
30
Arizona, Massachusetts, Pennsylvania, Texas, Virginia
2020-09-17
Active, closed
PF-07104091 as a Single Agent and in Combination Therapy
NCT04553133Small Cell Lung Cancer, Ovarian Cancer, Breast Cancer
DrugsPF-07104091·Palbociclib·Letrozole·Fulvestrant
Pfizer
Phase 2
157
Iowa, Kentucky, Massachusetts, New Jersey, New York, Virginia
2020-09-16
Active, closed
Study to Evaluate Loncastuximab Tesirine With Rituximab Versus Immunochemotherapy in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
NCT04384484Relapsed Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma
DrugsLoncastuximab Tesirine·Rituximab·Oxaliplatin·Gemcitabine
ADC Therapeutics S.A.
Phase 3
440
California, Florida, Iowa, Kentucky, Nevada, Oregon, South Carolina, Virginia
2020-09-16
Active, closed
A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot
NCT04564443Diabetic Foot Ulcer, Diabetic Foot
Medaxis, LLC
Not applicable
222
California, Florida, Maryland, North Carolina, Ohio, Virginia
2020-09-11
Active, closed
An Open-label, Phase 1/2 Trial of Gene Therapy 4D-310 in Adults With Fabry Disease
NCT04519749Fabry Disease
Drug4D-310
4D Molecular Therapeutics
Phase 1/2
18
California, Georgia, Pennsylvania, Virginia
2020-09-01
Recruiting
Non-Invasive Quantification of Liver Health in NASH (N-QUAN)
NCT04054310NASH - Nonalcoholic Steatohepatitis
Perspectum
Not applicable
225
Arizona, Illinois, Indiana, New York, Texas, Virginia
2020-08-05
By invitation
Cervical Interbody Implant Study
NCT04689854Degenerative Disc Disease, Cervical Spinal Instability
NuVasive
Observational
150
California, Connecticut, Massachusetts, Missouri, North Carolina, Ohio, Virginia
2020-07-07
Active, closed
Bilateral Treatment of Medication Refractory Essential Tremor
NCT04112381Essential Tremor
InSightec
Not applicable
51
California, Maryland, New York, Ohio, Pennsylvania, Virginia, West Virginia
2020-06-30
By invitation
Coronary CT Angiography Evaluation for Clinical Outcomes: An International Multicenter Registry
NCT04279496Coronary Artery Disease
Cleerly, Inc.
Observational
15,000
Virginia
2020-06-01
Active, closed
Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)
NCT04152499Epithelial Ovarian Cancer, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma, Urothelial Carcinoma
DrugSacituzumab tirumotecan
Klus Pharma Inc.
Phase 1/2
1,410
California, Florida, Michigan, Oklahoma, Oregon, Texas, Virginia
2020-02-28
Active, closed
ZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPD
NCT03911505Pompe Disease (Late-onset)
DrugsCipaglucosidase alfa·Miglustat
Amicus Therapeutics
Phase 3
21
Florida, Georgia, Missouri, North Carolina, Ohio, Pennsylvania, Utah, Virginia
2020-02-13
Active, closed
TAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations
NCT04129502Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
DrugsMobocertinib·Pemetrexed·Cisplatin·Carboplatin
Takeda
Phase 3
354
California, Florida, Illinois, Maryland, Massachusetts, Tennessee, Virginia
2020-01-10
Recruiting
Post Approval Study for Treatment of Drug-resistant Adult and Pediatric Primary FSGS Using the LIPOSORBER® LA-15 System
NCT04065438Focal Segmental Glomerulosclerosis
Kaneka Medical America LLC
Not applicable
35
California, Delaware, Michigan, New York, North Carolina, Ohio, South Carolina, Virginia
2020-01-01
Recruiting
Medtronic Cardiac Surgery PMCF Registry
NCT04073420Valve Disease, Heart
Medtronic Cardiac Surgery
Observational
2,700
Georgia, Michigan, New York, North Carolina, Ohio, Pennsylvania, Texas, Virginia
2019-12-02
Active, closed
Zephyr Valve Registry (ZEVR)
NCT04186546Emphysema
Pulmonx Corporation
Observational
150
Alabama, Illinois, Michigan, Pennsylvania, Texas, Virginia, Wisconsin
2019-11-25
Active, closed
A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis
NCT03958877Multiple Sclerosis, Relapsing-Remitting
DrugsPlegridy·Avonex
Biogen
Phase 3
152
California, North Carolina, Virginia
2019-10-18
Active, closed
MDR - Biomet Cannulated Screws
NCT04002518Fractures, Bone, Fracture Multiple
Zimmer Biomet
Observational
51
Indiana, Ohio, Virginia
2019-08-07
Active, closed
A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)
NCT04008030Metastatic Colorectal Cancer
DrugsFluorouracil·Leucovorin·Ipilimumab·Cetuximab
Bristol-Myers Squibb
Phase 3
839
California, Colorado, Illinois, New York, Oregon, Pennsylvania, Texas, Virginia
2019-08-05
Active, closed
Assessing an Oral EGFR Inhibitor, Sunvozertinib in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR or HER2 Mutation (WU-KONG1)
NCT03974022Non-Small Cell Lung Cancer
DrugSunvozertinib
Dizal Pharmaceuticals
Phase 1/2
315
California, Colorado, Florida, Massachusetts, Michigan, New York, Ohio, Virginia
2019-07-09
Active, closed
A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors
NCT03872947Solid Tumor, Colorectal Cancer, Cholangiocarcinoma, Bladder Cancer
DrugsTRK-950·Imiquimod·Ramucirumab·Leucovorin
Toray Industries, Inc
Phase 1
138
Arizona, California, Louisiana, New Jersey, New York, Oregon, Texas, Virginia
2019-04-26
Recruiting
Two Dose Levels of Privigen in Pediatric CIDP
NCT03684018Pediatric Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
DrugImmunoglobulins
CSL Behring
Phase 4
30
Arizona, California, Iowa, Ohio, Pennsylvania, Tennessee, Texas, Virginia
2019-02-28
Active, closed
Study of NEO-201 in Solid Tumors Expansion Cohorts
NCT03476681Non Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Cervical Cancer, Uterine Cancer
DrugPembrolizumab
Precision Biologics, Inc
Phase 1/2
121
Maryland, Virginia
2019-01-18
Active, closed
A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer
NCT03742102Triple Negative Breast Neoplasms
DrugsOleclumab·Capivasertib·Dato-DXd·Trastuzumab deruxtecan
AstraZeneca
Phase 1/2
243
Arizona, Maryland, Massachusetts, Michigan, Missouri, Texas, Virginia
2018-12-21
Active, closed
Post-Market Study of Comprehensive Reverse Augmented Glenoid and Mini Humeral Tray in Total Shoulder Arthroplasty
NCT03726554Arthropathy of Shoulder Region, Grossly Deficient Rotator Cuff, Osteoarthritis of the Shoulder, Rheumatoid Arthritis Without Humeral Metaphyseal Defects
Zimmer Biomet
Not applicable
99
Florida, Kentucky, Michigan, New York, Tennessee, Virginia
2018-08-28
Active, closed
Long-Term Safety and Efficacy of Spark-Sponsored Gene Therapies in Males With Hemophilia A
NCT03432520Hemophilia A
Spark Therapeutics, Inc.
Observational
29
Massachusetts, Mississippi, Missouri, Oregon, Pennsylvania, Virginia
2018-08-14
Active, closed
A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors
NCT03530397Selected Advanced Solid Tumors
DrugsVolrustomig·Nab-paclitaxel·Pemetrexed·Paclitaxel
MedImmune LLC
Phase 1
400
Michigan, New York, North Carolina, Rhode Island, Tennessee, Virginia
2018-04-24
Active, closed
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
NCT03423628Recurrent Glioblastoma Multiforme, Primary Glioblastoma Multiforme, Brain Neoplasms, Malignant, Leptomeningeal Disease (LMD)
DrugAZD1390
AstraZeneca
Phase 1
159
Massachusetts, New York, Pennsylvania, Virginia
2018-04-02
Recruiting
CardioFocus HeartLight Post-Approval Study
NCT03168659Atrial Fibrillation
CardioFocus
Not applicable
250
Arizona, Illinois, New York, Virginia
2017-06-16
Recruiting
Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source
NCT02843945Pancreatic Cancer
CivaTech Oncology
Phase 1/2
80
Florida, Illinois, Louisiana, Pennsylvania, Virginia
2017-05-31
Active, closed
Prospective G7 Dual Mobility Total Hip PMCF
NCT03308929Clinical Outcomes, Functional Outcomes, Radiological Outcomes, Survivorship
Zimmer Biomet
Observational
250
New Jersey, New Mexico, North Carolina, Oregon, Virginia
2017-02-28
Active, closed
A Study of ABBV-927 and ABBV-181, an Immunotherapy, in Participants With Advanced Solid Tumors
NCT02988960Advanced Solid Tumors Cancer
DrugsABBV-927·Budigalimab
AbbVie
Phase 1
163
California, Illinois, Massachusetts, North Carolina, Tennessee, Texas, Virginia
2017-02-22
Active, closed
Venglustat in Combination With Cerezyme in Adult Patients With Gaucher Disease Type 3 With Venglustat Monotherapy Extension
NCT02843035Gaucher Disease Type 1, Gaucher Disease Type 3
DrugsImiglucerase·Venglustat
Genzyme, a Sanofi Company
Phase 2
12
Connecticut, Texas, Virginia
2017-01-04
Active, closed
An Observational Prospective Long-term Exposure Registry of Adult Patients With Moderate-to-Severe Ulcerative Colitis
NCT02808780Ulcerative Colitis
Janssen Biotech, Inc.
Observational
535
California, Florida, Georgia, Illinois, Ohio, Pennsylvania, Texas, Virginia
2016-12-16
Active, closed
Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders:
NCT03100474Essential Tremor, Parkinson's Disease, Movement Disorders, Neuropathic Pain
InSightec
Observational
500
California, Maryland, Pennsylvania, Virginia, Washington
2016-12
Active, closed
A Prospective, Clinical Investigation of the Vanguard 360 Revision Knee
NCT01542580Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Post Traumatic Deformity
Zimmer Biomet
Observational
255
Illinois, Nevada, Utah, Virginia
2012-03
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 6 October 2026. https://priyalifescience.com/clinical-trials-usa/state/virginia

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,118 studies in total at the last sync on 06 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 481 of those studies with a site in Virginia.

How many clinical trials are recruiting in Virginia?

284 of the 481 studies on this page are recruiting new participants as of the 06 Oct 2026, 03:16 UTC sync. A further 17 have not yet opened recruitment, 166 are active but closed to new participants, and 14 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Virginia), 481 studies
PhaseStudiesRecruitingShare
Phase 11329927.4%
Phase 1/21006620.8%
Phase 2612312.7%
Phase 3613112.7%
Not applicable583012.1%
Observational532411%
Phase 2/31172.3%
Phase 4541%

Most active sponsors

Lead sponsors with the most studies (Virginia)
Lead sponsorStudiesRecruiting
AstraZeneca199
Merck Sharp & Dohme LLC1311
Janssen Research & Development, LLC84
AbbVie73
Gilead Sciences76
Pfizer73
Zimmer Biomet71
argenx52
Biogen52
Daiichi Sankyo54
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.