A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies
Condition(s) studied
Investigational drug(s) / intervention(s)
BMS-986523: Specified dose on specified days
Gemcitabine: Specified dose on specified days
Nab-Paclitaxel: Specified dose on specified days
Cetuximab: Specified dose on specified days
Pembrolizumab: Specified dose on specified days
Study summary
The purpose of this study is to evaluate the safety, tolerability, and efficacy of BMS-986523 alone and in combination with anti-cancer agents in participants with advanced solid malignancies
Eligibility
Primary outcome measure(s)
- Number of participants with adverse events (AEs) — Up to 3 years
- Number of participants with serious adverse events (SAEs) — Up to 3 years
- Number of participants with AEs meeting protocol-defined dose limiting toxicity (DLT) criteria — Up to 3 years
- Number of participants with AEs leading to discontinuation — Up to 3 years
- Number of deaths — Up to 3 years
Trial sites (8)
| Facility | City | Region | Status |
|---|---|---|---|
| Johns Hopkins Hospital | Baltimore | Maryland | Recruiting |
| NEXT Oncology | San Antonio | Texas | Recruiting |
| START Mountain Region | West Valley City | Utah | Recruiting |
| NEXT Virginia | Fairfax | Virginia | Recruiting |
| BC Cancer Vancouver | Vancouver | British Columbia | Recruiting |
| Princess Margaret Cancer Centre | Toronto | Ontario | Recruiting |
| Local Institution - 0006 | Badalona | Barcelona [Barcelona] | Not Yet Recruiting |
| Local Institution - 0008 | Hortaleza | Madrid | Not Yet Recruiting |
On this site
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Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07223047 on ClinicalTrials.gov ↗ ← All trials in the USA