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Clinical Trials in the USA / NCT07285070
Recruiting Phase 2

Tacrolimus Ophthalmic Solution for the Treatment of Non-infectious Anterior Uveitis

NCT07285070 · tracked via the Priya Life Science USA tracker
Sponsor
Novaliq GmbH
Phase
Phase 2
Started
2026-03-16
Last updated
2026-07-28

Condition(s) studied

Non-infectious Anterior Uveitis

Investigational drug(s) / intervention(s)

Tacrolimus ophthalmic solution

Tacrolimus ophthalmic solution: high and low dose treatment will be compared over 6 weeks treatment

Study summary

The primary objective of the study is to investigate the safety and tolerability of NOV05 eye drops at two concentrations QID in patients with active non-infectious anterior uveitis.

Eligibility

Sex
ALL
Min age
18 Years
Max age
Healthy volunteers
No
Inclusion Criteria: * Be ≥18 years of age; * Provide written informed consent; * Be diagnosed with active non-infectious anterior uveitis requiring initiation or increase of topical steroids administration for the management of ocular inflammation; * Have an onset of symptoms within 4 weeks; Exclusion Criteria: * Have severe/serious ocular pathology in the study eye which may preclude study completion or interferes with trial assessment, in the judgement of the clinical Investigator; * Have a history of or a current ocular or periocular malignancy; * Have active intermediate or posterior uveitis in the study eye or another documented posterior segment inflammation; * A confirmed or highly suspicious infectious uveitis eg, CMV, Herpes simplex, Herpes zoster, syphilis, tuberculosis, lyme disease; * Have a known allergy or sensitivity to the IMP tacrolimus or semifluorinated alkanes (SFA); * Be a woman who is pregnant, nursing, or planning a pregnancy; * Have a condition or be in a situation (e.g. language barrier, non-cooperative, history of substance abuse) which the Investigator considers that it may put the patient at significant risk, may confound the trial results, or may significantly interfere with the patient's participation in the trial;

Primary outcome measure(s)

Trial sites (6)

FacilityCityRegionStatus
Horizon Eye & Lasik Center Phoenix Arizona Recruiting
Bascom Palmer Eye Institute Miami Florida Recruiting
Massachusetts Eye Research and Surgery Institution Waltham Massachusetts Recruiting
Metropolitan Eye Research and Surgery Institute Palisades Park New Jersey Recruiting
Valley Retina Institute, P.A. McAllen Texas Recruiting
Virginia Eye Consultants Norfolk Virginia Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07285070 on ClinicalTrials.gov ↗ ← All trials in the USA