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Trackers› Clinical trials› Singapore
Clinical trial register · Singapore

Clinical Trials in Singapore

Every study on the ClinicalTrials.gov registry that lists a site in Singapore and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage โ€” all 948 matching records held by the registry are in this view. Synced 30 Sep 2026, 03:16 UTC
948
Studies in scope
all four open statuses
487
Recruiting now
open to new participants
153
Lead sponsors
across recruiting studies
Top sites
Singapore 939 Kent Ridge 5 Bukit Merah 4 Novena 3 Outram Park 2
Narrow the register
Recruitment status
Phase
Lead sponsor
National University Hospital, Singapore91 Novartis Pharmaceuticals60 KK Women's and Children's Hospital50 National University of Singapore48 Singapore General Hospital44
Site location
Singapore939 Kent Ridge5 Bukit Merah4 Novena3 Outram Park2
All 8 locations
Target enrolment
to

Trials in this register

948 of 948 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
Sites in Singapore
Start
Not yet open
Concurrent Trials on Nature-Based Therapy for Inpatients in Dementia and Rehabilitation Medicine Wards
NCT07059390Dementia, Acquired Brain Injury Including Stroke
Changi General Hospital
Not applicable
1,600
Singapore
2027-05
Not yet open
Combined rTMS and tSCS for Upper Limb Recovery in Cervical SCI
NCT07586644Spinal Cord Injuries (SCI)
National University Hospital, Singapore
Not applicable
24
Singapore
2027-03-30
Not yet open
Frailty Improvement Through Technology With Informal Caregiver Supported Exercise (FITWISE) for Pre-frail and Frail Community-dwelling Older Adults
NCT07519642Frailty, Pre-Frailty
National University of Singapore
Not applicable
60
Singapore
2027-02-01
Not yet open
Combined TMS-tSCS for Lower Limb Rehabilitation in Chronic Incomplete SCI
NCT07595497Spinal Cord Injuries (SCI)
National University Hospital, Singapore
Not applicable
24
Singapore
2027-01-01
Not yet open
tACS and Upper Limb Rehabilitation in Chronic Stroke
NCT07778342Stroke
National University Hospital, Singapore
Not applicable
34
Singapore
2026-12-01
By invitation
Community Study to Increase Mammogram Screening Among Overdue Women
NCT07832396This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women in Real World
National University Hospital, Singapore
Not applicable
15,000
Singapore
2026-11-01
Not yet open
Sacituzumab Tirumotecan in Recurrent/Metastatic Adenoid Cystic Carcinoma and Papillary Thyroid Carcinoma (STRAP)
NCT07521670Recurrent Adenoid Cystic Carcinoma, Adenoid Cystic Carcinoma Metastatic, Papillary Thyroid Carcinoma
DrugSacituzumab tirumotecan
National Cancer Centre, Singapore
Phase 2
68
Singapore
2026-11
Not yet open
Lifescapes System in Post-stroke Hand Recovery
NCT07784920Stroke
National University Hospital, Singapore
Not applicable
32
Singapore
2026-10-01
Recruiting
Study Protocol: The Efficacy of Mushroom to Reduce Cognitive Decline in At-Risk Middle-aged Adults and Young-olds Living in the Community
NCT07775833Dementia, Cognitive Assessment
National University of Singapore
Not applicable
600
Singapore
2026-10
Not yet open
Comparing Myopia Control Spectacle Lenses and Standard Single Vision Spectacle Lenses in Children With Myopia
NCT07839091Myopia, Myopia Progression
Essilor International
Not applicable
20
Singapore
2026-10
Recruiting
Effectiveness of the Personalized Responses & Integrated Systems for Metabolism (PRISM) on Improving Insulin Resistance Among Adults With Metabolic Syndrome: A Pilot Study (PRISM-I)
NCT07710274Metabolic Syndrome (MetS)
National University Health System, Singapore
Not applicable
200
Singapore
2026-09-17
Recruiting
A Study to Evaluate the Efficacy of VVD-133214 in Combination With Pembrolizumab Compared With Pembrolizumab Alone in Participants With Advanced Cancer of the Colon or Rectum
NCT07811193Colorectal Adenocarcinoma
DrugsVVD-133214·Pembrolizumab
Vividion Therapeutics, Inc.
Phase 2
140
Singapore
2026-09-11
Recruiting
A Study of Abemaciclib (LY2835219) in Healthy Participants
NCT07818967Healthy Volunteers
DrugAbemaciclib
Eli Lilly and Company
Phase 1
15
Singapore
2026-09-02
Not yet open
Measurement of Acute Metabolite Changes Following Consumption of Microalgae Drinks
NCT07791420Protein Absorption and Amino Acid Availability, Metabolomics
National University of Singapore
Not applicable
20
Singapore
2026-09-01
Not yet open
Platform for End-of-life Awareness, Conversations, and Education (PEACE) Among Registered Nurses
NCT07774468Death Anxiety, Death Attitude (Implicit/Explicit), End of Life Care, Advanced Care Planning (ACP)
National University of Singapore
Not applicable
150
Singapore
2026-09-01
Not yet open
Tailored Brain Health Insights Through Nurturing Knowledge-based Change - Stakeholder-driven, Human-centered, AI-powered Refinement for Prevention
NCT07612800MCI, Dementia
Alexandra Hospital
Not applicable
350
Singapore
2026-09-01
Not yet open
Mapping the Neural Circuits of Depression and Anxiety Using Personalized, Accelerated TMS and Deep Phenotyping
NCT07766291Depression Disorder
National University Hospital, Singapore
Not applicable
36
Singapore
2026-09-01
By invitation
Pragmatic Mobile Health Trial to Promote Cancer Screening and Healthy Behaviors
NCT07725328Cancer Screening, Chronic Diseases in Older Adults, Early Cancer Detection, Mammography
National University Hospital, Singapore
Not applicable
2,000
Singapore
2026-09-01
Not yet open
TTNS in SCI Patients With Neurogenic Detrusor Overactivity
NCT07785258Spinal Cord Injuries, Neurogenic Detrusor Overactivity
National University Hospital, Singapore
Not applicable
12
Singapore
2026-09-01
Not yet open
Effect of Co-consuming Different Dietary Protein Sources With Salad on the Bioavailability of Carotenoids
NCT07795372Postprandial Carotenoid Response
National University of Singapore
Not applicable
19
Singapore
2026-09
Not yet open
Maintenance Individualized Neuromodulation and Depression-detection Via Sensors for Early Treatment
NCT07779330Depression Disorder
National University Hospital, Singapore
Not applicable
24
Singapore
2026-09
Not yet open
Improving Diet Quality of Community-Dwelling Seniors Using a Community-Based Participatory Approach
NCT07838142Diet Quality, Feasibility of Food Literacy Education Program, Social Isolation in Older Adults
Geriatric Education and Research Institute
Not applicable
50
Singapore
2026-09
Not yet open
A Study of LY4329090 in Participants With Obesity or Overweight Who Are Otherwise Healthy
NCT07808073Obesity, Overweight
Eli Lilly and Company
Phase 1
184
Singapore
2026-09
Not yet open
Personalized and Accelerated Transcranial Magnetic Stimulation for Treatment-resistant Anxiety Related Disorders
NCT07801391Anxiety and Fear-Related Disorders
National University Hospital, Singapore
Not applicable
24
Singapore
2026-09
Not yet open
Nurse Led Aromatherapy
NCT07773181Burns and Scalds
KK Women's and Children's Hospital
Not applicable
100
Singapore
2026-09
Recruiting
A Study of LY4226695 in Healthy Participants
NCT07767487Healthy
Eli Lilly and Company
Phase 1
148
Singapore
2026-08-27
Not yet open
A Phase III, Multicentre Study to Evaluate Consolidation Treatment With AZD0120 Compared With ASCT, in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (DURGA-6).
NCT07735637Newly Diagnosed Multiple Myeloma (NDMM)
DrugsASCT·AZD0120·Melphalan·Lenalidomide
AstraZeneca
Phase 3
750
Singapore
2026-08-25
Not yet open
Effects of a Digital AI-Mediated Mindful Eating Intervention on Eating Behavior and Well-Being Outcomes in College Students
NCT07784972Health Behavior Change
Singapore Management University
Not applicable
250
Singapore
2026-08-21
Not yet open
Impact of Antioxidant-rich Supplementation on Skin Carotenoids Status, Antioxidant Status and Cardiometabolic Health in Overweight and Obese Individuals
NCT07748468Overweight , Obesity, Antioxidant Status
National University of Singapore
Not applicable
83
Singapore
2026-08-15
Recruiting
Targeted Lens Intervention for Myopic Anisometropia in Children
NCT07533149Anisometropia, Myopia
Essilor International
Not applicable
20
Singapore
2026-08-13
Recruiting
The Cardiovascular-Cognitive Health Initiative
NCT07829380Cognitive Impairment
National Heart Centre Singapore
Not applicable
5,000
Singapore
2026-08-04
Not yet open
Formative Evaluation of a Mobile Application Facilitated Self-directed Rehabilitation Programme for Knee Osteoarthritis
NCT07773480Knee Osteoarthritis
Singapore General Hospital
Not applicable
30
Singapore
2026-08-01
Not yet open
Effectiveness, Acceptability and Feasibility of a Communication and Care Coordinator (CCC) Model in Facilitating Serious Illness Communication (SIC) and Care in Patients With Cancer
NCT07733973Cancer
National Cancer Centre, Singapore
Not applicable
560
Singapore
2026-08-01
Not yet open
Effectiveness and Implementation of 'Supportive and Palliative Care Review Kit in Locations Everywhere'
NCT07745816Neoplasms, Palliative Care
National Cancer Centre, Singapore
Not applicable
300
Singapore
2026-08-01
Not yet open
Alzheimer's Disease THErapy With NEuroaid II
NCT07191028Alzheimer's Disease Dementia
Moleac Pte Ltd.
Phase 3
350
Singapore
2026-08
Recruiting
A First-in Human Study of ARD001 in Healthy Volunteers and People With Hemophilia A
NCT07787091Hemophilia A, Healthy Adult Participants
Arditus Pte Ltd
Phase 1/2
20
Singapore
2026-08
Not yet open
Tislelizumab in Combination With Bevacizumab and Capecitabine in Advanced Solid Tumors With Evaluation in Immunotherapy-Resistant and Central Nervous System Disease
NCT07681297Advanced Solid Tumor Cancer, Triple-Negative Breast Cancer (TNBC), CNS Disease, Breast Cancer
DrugsTislelizumab·Capecitabine·Bevacizumab
National University Hospital, Singapore
Phase 1/2
154
Singapore
2026-08
Not yet open
A Pilot Evaluation of Refractive Error Progression in Pre-Myopic Children in Singapore With and Without Myopia Control Spectacles
NCT07779941Myopia, Pre-myopia
Singapore National Eye Centre
Not applicable
124
Singapore
2026-08
Not yet open
Durian Consumption in Adults With Type 2 Diabetes Mellitus
NCT07697612Type 2 Diabetes
Singapore General Hospital
Not applicable
40
Singapore
2026-08
Recruiting
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight
NCT07738614Obesity, Overweight
DrugsEloralintide·Acetaminophen
Eli Lilly and Company
Phase 1
56
Singapore
2026-07-31
Recruiting
A Phase 2 Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib (LOU064) in Adult Patients With Papulopustular Rosacea (PPR)
NCT07681271Papulopustular Rosacea
DrugRemibrutinib
Novartis Pharmaceuticals
Phase 2
100
Singapore
2026-07-30
Recruiting
A Study on the Acquisition of 2D ICE Images With the CHORUS IDx System in Subjects Undergoing an Ablation Procedure
NCT07353710Atrial Arrhythmia, Intracardiac Echocardiography
Boston Scientific Corporation
Not applicable
200
Singapore
2026-07-28
Recruiting
A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis
NCT07497087Systemic Sclerosis
Boehringer Ingelheim
Phase 3
448
Singapore
2026-07-27
Not yet open
Advancing Precision Medicine for Cardiovascular Disease and Diabetes in Asian Populations: Digital Intervention Cohort
NCT07728799Physical Activity, Diet Quality, Sleep, Cardiometabolic Health
National University of Singapore
Not applicable
600
Singapore
2026-07-20
Recruiting
Bonding Before Birth: A mHealth Intervention for First-time Expectant Couples
NCT07483515Anxiety, Pregnancy, Parenting Self-efficacy, Stress (Psychology)
Institute for Human Development and Potential (IHDP), Singapore
Not applicable
572
Singapore
2026-07-06
Recruiting
Internet-Based Cognitive Behavioural Therapy (iCBT) for Anxiety and Depression in Singapore
NCT07532551Depression and/or Anxiety in the Mild-to-moderate Range, Cognitive Behavioral Therapy
National University of Singapore
Not applicable
390
Singapore
2026-07-02
Recruiting
Multimodal Prehabilitation in Gastric Cancer Patients
NCT07839702Gastric Cancer (GC), Prehabilitation, Postoperative Inflammation
National University Hospital, Singapore
Not applicable
25
Singapore
2026-07-01
Not yet open
Optimising Exercise to Improve Physical and Cognitive Frailty in Mild Cognitive Impairment
NCT07600034Mild Cognitive Impairment (MCI)
Universiti Sains Malaysia
Not applicable
36
Singapore
2026-07-01
Not yet open
Bepirovirsen Liver Biopsy Study
NCT07696520HEPATITIS B CHRONIC, Hepatitis B Chronic Infection
DrugBepirovirsen
National University Health System, Singapore
Phase 2
30
Singapore
2026-07-01
Not yet open
Electroacupuncture for Cognitive Toxicity in Cancer Survivors: Assessing Implementation, Cost, and Effectiveness for Integration
NCT07583979Cancer-related Cognitive Impairment
National Cancer Centre, Singapore
Phase 3
168
Singapore
2026-07-01
Not yet open
Restoring Bile Acid Homeostasis Via Lifestyle Adjustments to Prevent the Development of Liver Cancer
NCT07111130Liver Diseases
National Cancer Centre, Singapore
Not applicable
90
Singapore
2026-07
Not yet open
Home Play-based Intervention for Parents and Infants
NCT07716072Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder, Premature Birth, Global Developmental Delay
Nanyang Technological University
Not applicable
120
Singapore
2026-07
Recruiting
Study of Ianalumab in Adults With Primary Immune Thrombocytopenia (ITP) and Warm-antibody Autoimmune Hemolytic Anemia (wAIHA) Who Have Previously Benefited From Ianalumab
NCT07039422Primary Immune Thrombocytopenia, Warm Autoimmune Hemolytic Anemia
DrugIanalumab
Novartis Pharmaceuticals
Phase 2
60
Singapore
2026-06-26
Recruiting
A Study of LY4174794 in Participants With Obesity or Overweight Who Are Otherwise Healthy
NCT07654972Obesity, Overweight
Eli Lilly and Company
Phase 1
108
Singapore
2026-06-24
Recruiting
Outpatient Physiotherapy vs. mHealth Exercise and Self-Management for Knee Osteoarthritis (MOKneeTOR)
NCT07767409Knee Osteoarthristis
Singapore General Hospital
Not applicable
160
Singapore
2026-06-18
Recruiting
A Study to Evaluate DJI136, a DLL3-targeted CAR-T Therapy
NCT07564401Extensive-stage Small Cell Lung Cancer (ES-SCLC)
Novartis Pharmaceuticals
Phase 1/2
80
Singapore
2026-06-16
Recruiting
Developing and Testing the Effectiveness of a Skin Cancer Self-Detection Educational Program
NCT07247123Skin Cancer, Skin Cancer Prevention, Benign Skin Growth
National University Hospital, Singapore
Not applicable
280
Singapore
2026-06-15
Recruiting
Sensory Enrichment Using Aromatherapy for Neurobehavioral and Psychological Symptoms in Early Dementia
NCT07234357Mild Cognitive Impairment, Mild Dementia
National Cancer Centre, Singapore
Not applicable
200
Singapore
2026-06-09
Recruiting
Inhalation Aromatherapy for Patients Undergoing Conservative Sharp Wound Debridement:
NCT07732036Aromatherapy
Singapore General Hospital
Not applicable
40
Singapore
2026-06-05
Not yet open
Assessing Biological Aging in a Real-World Medical Weight Loss Program Using the LinAge2 Clinical Clock
NCT07444073Aging, Obesity & Overweight
National University of Singapore
Observational
440
Singapore
2026-06-01
Recruiting
Complementary Herbal Approach to Rheumatoid Management Study (CHARMS)
NCT07627893Rheumatoid Arthritis (RA)
DrugMethotrexate
Singapore General Hospital
Phase 2/3
132
Singapore
2026-06-01
Recruiting
Investigating the Effect of Caffeine and Alcohol on Pupil Dynamics
NCT07625358Caffeine, Alcohol, Pupillary Response, Eye Movements
National University of Singapore
Not applicable
100
Singapore
2026-06-01
Not yet open
The SAVOR Study: Appetite and Physiological Responses
NCT07636369Anorexia of Aging, Malnutrition or Risk of Malnutrition
Singapore Institute of Food and Biotechnology Innovation
Not applicable
20
Singapore
2026-06
Not yet open
An International Multicenter, Multivendor Evaluation of the Free-Running Framework for Cardiac Function
NCT07613398Congenital Heart Diseases, Cardiac Diseases
Matthias Stuber
Observational
300
Singapore
2026-06
Not yet open
siRNA Microneedle Patches for Ear Keloid Post-Surgical Scars
NCT07596628Keloid of Ear Lobe
Ong Kim Yao
Phase 2
158
Singapore
2026-06
Not yet open
Evaluating the Optimal Timing of Acupuncture for Managing Chemoradiation-induced Xerostomia in Patients With Head and Neck Cancers
NCT07674706Xerostomia, Head Cancer, Neck Cancer, Nasopharyngeal Carcinoma (NPC)
National University Hospital, Singapore
Not applicable
50
Singapore
2026-06
Not yet open
Silver-Impregnated Dressings for Catheter Exit-Site and Tunnel Infections in Peritoneal Dialysis Patients
NCT07641491Peritoneal Dialysis Catheter Exit Site Infection, Peritoneal Dialysis Catheter Tunnel Infection
Singapore General Hospital
Not applicable
60
Singapore
2026-06
Recruiting
Study of IEV407 as Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer
NCT07604571Advanced HR+/HER2- Breast Cancer
DrugsLetrozole·Fulvestrant
Novartis Pharmaceuticals
Phase 1
194
Singapore
2026-05-28
Recruiting
LOVING (Learning About Our Behavior is Valuable for Increasing Nurturing Relationships and Healthy Growth) RCT
NCT07687524Child Development, Child Behavioral Problems, Parent Child Relationship
National University of Singapore
Not applicable
624
Singapore
2026-05-25
Recruiting
A Study of LY3439539 in Participants With Alzheimer's Disease
NCT07598370Alzheimer Disease
Eli Lilly and Company
Phase 1
30
Singapore
2026-05-21
Recruiting
USAGE OF ARITIFICIAL INTELLIGENCE IN AIDING WITH COLONIC SESSILE SERRATED LESIONS DETECTION AND DIAGNOSIS (AI-SSL)
NCT07650344Sessile Serrated Lesion, CADe
National Healthcare Group, Singapore
Not applicable
628
Singapore
2026-05-21
Recruiting
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
NCT07543120Hypertension (HTN)
DrugQCZ484
Novartis Pharmaceuticals
Phase 2
323
Singapore
2026-05-07
Recruiting
A Study of LY4302814 in Healthy Participants
NCT07566338Healthy
Eli Lilly and Company
Phase 1
150
Singapore
2026-05-06
Recruiting
A Solid Tumor Study for Long Term Treatment of Cancer Patients Who Participated in Adagrasib Studies
NCT07415031Solid Tumors
DrugsAdagrasib·Fluorouracil·Leucovorin·Irinotecan
Mirati Therapeutics Inc.
Phase 2
170
Singapore
2026-05-06
Not yet open
SOMA Validation RCT: Testing Structural Equivalence and Mechanistic Orthogonality of an Open-Source Mindfulness Stimulus Library
NCT07556744Mindfulness, Healthy Volunteers
Institute for Human Development and Potential (IHDP), Singapore
Not applicable
360
Singapore
2026-05-05
Recruiting
AP-NOSES: A Prospective Multicentre Registry of Natural Orifice Specimen Extraction in Minimally Invasive Colorectal Surgery
NCT07615036Colorectal Neoplasms, Incisional Hernia
Singapore General Hospital
Observational
800
Singapore
2026-05-05
Not yet open
Mandibular Advancement to Reduce Ventricular Load and Improve Quality-of-life in Heart Failure
NCT07460505Heart Failure, OSA - Obstructive Sleep Apnea
National University Hospital, Singapore
Not applicable
328
Singapore
2026-05-01
Recruiting
Early Pregnancy Lifestyle and Glucose Patterns: A Substudy of TOFFFY
NCT07534670Continuous Glucose Monitoring, Diabetes, Gestational, Diet During Pregnancy, Meal Time
KK Women's and Children's Hospital
Not applicable
140
Singapore
2026-05-01
Not yet open
Improving Care for Frail Older Adults Using a Digital Needs Assessment Tool
NCT07580690Frail Elderly Patients, Geriatric Syndromes, Frail Older Adults
Duke-NUS Graduate Medical School
Not applicable
200
Singapore
2026-05-01
Not yet open
Evaluating Ivonescimab in PD-1 Resistant Recurrent or Metastatic Nasopharyngeal Carcinoma
NCT07565389Nasopharyngeal Carcinoma (NPC)
DrugIvonescimab
National University Hospital, Singapore
Phase 2
42
Singapore
2026-05
Not yet open
AI-Powered Closed-Loop Multielectrode Transcutaneous Spinal Cord Stimulation: Real-Time Adjustments for Enhanced Motor Recovery in Spinal Cord Injury (AIM RECOVER)
NCT07452133Spinal Cord Injury
Singapore General Hospital
Not applicable
7
Singapore
2026-05
Recruiting
DORA - A Study Using Digital Health Tools/Platform to Explore the Impact of the Consumption of Senior Milk Powder Containing Synbiotics on the Gut micRobiome in Healthy Aging Individuals
NCT07575529Healthy Adult Participants, Gut Microbiomes, AI
Danone Asia Pacific Holdings Pte, Ltd.
Not applicable
100
Singapore
2026-04-27
Not yet open
Investigating Cognitive Flexibility Training
NCT07556250Healthy
Nanyang Technological University
Not applicable
225
Singapore
2026-04-23
By invitation
Open-Label, Long-Term, Extension Study of Infigratinib in Children With Hypochondroplasia
NCT07393373Hypochondroplasia
DrugInfigratinib
QED Therapeutics, a BridgeBio company
Phase 2
135
Singapore
2026-04-23
Active, closed
A Study of Eltrekibart (LY3041658) in Healthy Participants
NCT07545590Healthy
DrugEltrekibart
Eli Lilly and Company
Phase 1
60
Singapore
2026-04-21
Recruiting
Fostering Self-Empowerment in CKD Patients Through Food Choice Mapping
NCT07804316CKD, Chronic Kidney Disease (Stages 3b-5)
Singapore Institute of Technology
Observational
30
Singapore
2026-04-15
Recruiting
Virtual Menstrual Pain Approaches in Females
NCT07497711Pain (Visceral, Somatic, or Neuropathic), Women of Reproductive Age, Mental Disorder, Digital Health
Nanyang Technological University
Phase 2/3
145
Singapore
2026-04-15
Recruiting
A Study to Learn More About How Safe BAY 3771249 is and How Well it Works in People With Advanced or Metastatic Colorectal Cancer That Has a KRAS G12D Mutation
NCT07535112Advanced/Metastatic Colorectal Adenocarcinoma
DrugCetuximab
Bayer
Phase 1
130
Singapore
2026-04-07
Not yet open
Die-logue Program for Community Dwelling Adults: A Randomized Controlled Trial
NCT07525492Death Attitude (Implicit/Explicit), Death Anxiety, End of Life Care, Advanced Care Planning (ACP)
National University of Singapore
Not applicable
148
Singapore
2026-04-01
Recruiting
Salt Intake and Blood Pressure Control in Adults With Essential Hypertension
NCT07025928Hypertension
Sun Jingfeng
Not applicable
190
Singapore
2026-04-01
Recruiting
Feasibility, Safety and Efficacy of a Predominantly Plant-based Diet in an Asian Population With Chronic Kidney Disease
NCT07544524Chronic Kidney Disease stage3, Chronic Kidney Disease stage4, Diet Habit
Changi General Hospital
Not applicable
40
Singapore
2026-04-01
Not yet open
Integrating Allogeneic NK Cells in High-risk Advanced Stage III-IV Nasopharyngeal Cancer Patients
NCT07247201Nasopharyngeal Carcinoma (NPC), Minimal Residual Disease, Recurrent Nasopharyngeal Carcinoma, Maximum Tolerated Dose
Singapore General Hospital
Phase 1/2
31
Singapore
2026-04
Not yet open
Home-Based Digital Rehabilitation Program Optimized With Transcutaneous Spinal Cord Stimulation for Upper Limb Functional Enhancement in Tetraplegia (HOPE): A Safety, Efficacy, and Feasibility Study
NCT07438353Spinal Cord Injury, Quadriplegia/Tetraplegia
Singapore General Hospital
Not applicable
9
Singapore
2026-04
Not yet open
Asia Myelodysplastic Syndrome (MDS) Registry
NCT07355478Myelodysplastic Syndromes (MDS)
Bristol-Myers Squibb
Observational
500
Singapore
2026-03-26
Recruiting
Improving Artificial Intelligence-derived Algorithms for Estimating Length and Weight in NEonateS and infanTs up to 6 Months of Age (NEST)
NCT07514182Growth, Neonates, AI (Artificial Intelligence)
Danone Asia Pacific Holdings Pte, Ltd.
Observational
60
Singapore
2026-03-26
Active, closed
Influence of Tea Consumption on Human Glycemic Response
NCT07609004Glycaemic Response
National University of Singapore
Not applicable
20
Singapore
2026-03-25
Recruiting
Coaching in Palliative Surgical Oncology
NCT07789093Palliative Care, Advanced Cancer
Singapore General Hospital
Not applicable
220
Singapore
2026-03-24
Recruiting
Building Cognitive Behavioural Skills With StoryBooks to Reduce Emotional Difficulties in Kindergarten Years
NCT07425951Anxiety, Coping Skills, Socio-emotional Well-being
Nanyang Technological University
Not applicable
56
Singapore
2026-03-23
Recruiting
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
NCT07355296Proteinuric Kidney Diseases
DrugApecotrep
Boehringer Ingelheim
Phase 2
132
Singapore
2026-03-23
Recruiting
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
NCT07361497Non-small Cell Lung Cancer (NSCLC)
DrugsPumitamig·Durvalumab
Bristol-Myers Squibb
Phase 3
850
Singapore
2026-03-16
Recruiting
Video-based Intervention to Reduce Anxiety in Patients Undergoing Elective PCI
NCT07485088Procedural Anxiety, Coronary Artery Disease, Percutaneous Coronary Intervention Patients
Tan Tock Seng Hospital
Not applicable
144
Singapore
2026-03-16
Recruiting
A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)
NCT07291076Hepatocellular Carcinoma (HCC)
DrugsPumitamig·Yervoy·Ipilimumab
Bristol-Myers Squibb
Phase 1/2
198
Singapore
2026-03-16
Recruiting
A Real-world Study to Investigate Cardiovascular Risk Profile Among Newly Diagnosed Type 2 Diabetes Mellitus (T2DM) Participants
NCT07532863Diabetes Mellitus, Type 2
Novo Nordisk A/S
Observational
400
Singapore
2026-03-13
Recruiting
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 โ‰ฅ 50%. (ROSETTA Lung-202)
NCT07361510Non-Small Cell Lung Cancer (NSCLC)
DrugsPumitamig·Pembrolizumab
Bristol-Myers Squibb
Phase 3
750
Singapore
2026-03-12
Recruiting
The eHealth Integrated Maternal Physical Activity Programme in Prenatal Care Trial (E-IMPACT)
NCT07466797Physical Activity, Health Behavior
KK Women's and Children's Hospital
Not applicable
100
Singapore
2026-03-09
Recruiting
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
NCT07491445Pancreatic Cancer, Pancreatic Cancer Metastatic, PDAC, PDAC - Pancreatic Ductal Adenocarcinoma
DrugsCetuximab·Nab-paclitaxel·Gemcitabine
Revolution Medicines, Inc.
Phase 3
900
Singapore
2026-03-09
By invitation
Trial to Evaluate the Impact of Various Pragmatic Interventions to Increase Mammography Uptake Among Defaulted Repeat Screeners in Singapore
NCT07651345Mammogram Uptake, Breast Cancer, Breast Neoplasm, Early Detection of Cancer
National University Hospital, Singapore
Not applicable
12,750
Singapore
2026-03-09
Recruiting
Phase 2 Study of AHB-137 in HBeAg Negative Chronic Hepatitis B (CHB) Participants in Asia Pacific Region
NCT07370207Hepatitis B, Chronic
DrugAHB-137
AusperBio Therapeutics Inc.
Phase 2
84
Singapore
2026-03-06
Recruiting
Antigen Targeted T Cell Therapy for Relapsed/Refractory B Cell Lymphomas
NCT07319676B-cell Lymphoma Refractory
National University Hospital, Singapore
Phase 1/2
30
Singapore
2026-03-02
Recruiting
A Controlled Human Infection Model of Dengue
NCT07412483Dengue
Tan Tock Seng Hospital
Not applicable
5
Singapore
2026-03
Not yet open
Effectiveness of a Community-based Intervention Programme to Promote Well-being in Older Adults
NCT07400081Well-being/Quality of Life, Mental Health
National Healthcare Group Polyclinics
Not applicable
300
Singapore
2026-03
Not yet open
Effectiveness of an Web Application in Enhancing Informal Caregivers' Nasogastric Tube Feeding Competency
NCT07414563Nasogastric Feeding, Training Family Caregivers, Family Caregivers, Informal Caregiver
Tan Tock Seng Hospital
Not applicable
136
Singapore
2026-03
Not yet open
A Study to Compare Two Different Sleep Tests in Participants With No Symptoms or Early Symptoms of Alzheimer's Disease
NCT07485153Alzheimer's Disease, Early Alzheimer's Disease, Memory Problems
Eli Lilly and Company
Observational
35
Singapore
2026-03
Not yet open
Effectiveness of Two Icodextrin Exchanges on Fluid Status and Blood Pressure Control Compared to a Single Icodextrin Exchange
NCT07168343Children on Chronic Peritoneal Dialysis
National University Health System, Singapore
Not applicable
10
Singapore
2026-02-28
Recruiting
Use of a Digital Psychotherapeutic App to Reduce Symptom Burden in Dermatology Patients
NCT06702293Eczema, Psoriasis, Urticaria
National University Hospital, Singapore
Not applicable
690
Singapore
2026-02-23
Active, closed
Conversion Surgery for Gastric Cancer With Peritoneal Metastases (CONVERGENCE)
NCT07241715Gastric Cancer Stage IV, Peritoneal Metastasis
National University Hospital, Singapore
Phase 2/3
300
Singapore
2026-02-21
Recruiting
A Study to Find Out if BI 764198 Helps Adults and Adolescents With a Kidney Condition Called Focal Segmental Glomerulosclerosis (FSGS)
NCT07220083Focal Segmental Glomerulosclerosis
DrugApecotrep
Boehringer Ingelheim
Phase 3
286
Singapore
2026-02-16
Recruiting
Scalp Hair Metabolomics in Severe Obesity
NCT07368842Obesity & Overweight, Hair Loss, Metabolomics, Bariatric Surgery
Singapore General Hospital
Observational
60
Singapore
2026-02-07
Active, closed
Community-based Mobile-assisted Brief Intervention for Smoking Cessation
NCT07375459Smoking &Amp; Tobacco Cessation
National University of Singapore
Not applicable
100
Singapore
2026-02-04
Not yet open
Soluble and Osmotic Fibre (SOLOS) Diet for Constipation
NCT07388589Constipation, Constipation - Functional, Constipation Chronic Idiopathic, Constipation Predominant Irritable Bowel Syndrome
Singapore Institute of Technology
Observational
180
Singapore
2026-02-02
Recruiting
Early Sepsis Recognition Tool
NCT07397689Infection, Sepsis
KK Women's and Children's Hospital
Observational
40,000
Singapore
2026-02-01
Recruiting
PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE)
NCT07421882Out-Of-Hospital Cardiac Arrest, Cardiopulmonary Resuscitation, Death, Sudden, Cardiac, Therapeutic Hypothermia
Singapore General Hospital
Not applicable
50
Singapore
2026-02-01
Recruiting
EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors
NCT07262619Advanced Solid Tumors, MSI-H or dMMR Advanced Solid Tumors, MSI-H/dMMR Gastric Cancer, MSI-H/dMMR Colorectal Cancer
DrugsKeytruda·Pembrolizumab
Eikon Therapeutics
Phase 1/2
160
Singapore
2026-01-20
Active, closed
A Study of Dengue Tetravalent Vaccine (TDV) in Adults (Age 45 to 60 and >60 to 79 Years)
NCT06579755Dengue Fever
Takeda
Phase 3
800
Singapore
2026-01-20
Recruiting
Impact of Supplementation in Improving Metabolic Health Outcomes (ISMOS) Study
NCT07433049Glucose Control, Mental Health, Musculoskeletal Health, Body Composition
Institute for Human Development and Potential (IHDP), Singapore
Not applicable
400
Singapore
2026-01-20
Recruiting
Effects of Pulsed Electromagnetic Field Therapy on Sport Performance and Recovery
NCT07288892Sport Performance, Sport Recovery, Athlete
Nanyang Technological University
Not applicable
30
Singapore
2026-01-19
Recruiting
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
NCT07195695Non-small Cell Lung Cancer
DrugsZongertinib·Atezolizumab·Durvalumab·Nivolumab
Boehringer Ingelheim
Phase 3
400
Singapore
2026-01-16
Not yet open
Trial of Aldosterone-hybrid SteRoid for Guiding curablE Treatment of Primary Aldosteronism (TARGET-PA)
NCT07297745Hyperaldosteronism; Primary, Primary Aldosteronism Due to Aldosterone Producing Adenoma
Changi General Hospital
Not applicable
120
Singapore
2026-01-15
Active, closed
A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus
NCT07299084Diabetes Mellitus, Type 2, Overweight, Obesity
DrugTirzepatide
Eli Lilly and Company
Phase 1
40
Singapore
2026-01-14
Recruiting
Ganglion Resection Effectiveness Trial
NCT07162415Wrist Ganglion, Ganglion, Ganglion Cyst, Connective Tissue Disease
Tampere University Hospital
Not applicable
220
Singapore
2026-01-13
Recruiting
A Clinical Study to Assess the Efficacy of Adjuvant Immunotherapy With Cemiplimab in Patients With Surgically Removed Non-small Cell Lung Cancer Who Have Not Received Prior Chemotherapy
NCT06931717Non-Small Cell Lung Cancer
DrugCemiplimab
ETOP IBCSG Partners Foundation
Phase 3
390
Singapore
2026-01-12
Recruiting
A Randomized Controlled Trial Comparing Whole Body Vibration Therapy With Usual Care and Usual Care to Improve Muscle Health in Older Adults
NCT07205133Aging, Frailty, Sarcopenia, Muscle Strength
Changi General Hospital
Not applicable
40
Singapore
2026-01-10
Recruiting
Effectiveness of Large Language Model for Anaesthesia and Procedural Consent
NCT06949462Consent Forms, Anesthesia, Artificial Intelligence (AI)
Singapore General Hospital
Not applicable
120
Singapore
2026-01-07
Recruiting
CPAP vs MAD for OSA in Patients With Cognitive Impairment. A Randomized Clinical Trial
NCT06983769Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment
National University Hospital, Singapore
Not applicable
260
Kent Ridge
2026-01-01
Recruiting
Effectiveness and Implementation of a Community-based Health Coach-led Artificial Intelligence (AI)-Powered Digital Self-Regulation Program for Individuals With Metabolic Syndrome (MetS)
NCT07410325Metabolic Syndrome (MetS), Metabolic Syndrome
National University Health System, Singapore
Not applicable
316
Singapore
2026-01-01
Recruiting
Global Reference Ranges - Singapore
NCT07166471Healthy Participants
Perspectum
Observational
50
Singapore
2026-01-01
Recruiting
Regime for Vitamin D Maintenance in Post-Operative Patients
NCT06708741Sarcopenia
DrugVitamin D
Sengkang General Hospital
Phase 3
100
Singapore
2026-01-01
Recruiting
Focal or Radical Therapy: a Lesion-based Molecular Evaluation in Prostate Cancer
NCT07282808Prostate Cancer
Singapore General Hospital
Not applicable
130
Singapore
2026-01
Not yet open
User-centric Study of Patients' Receptiveness Towards the Web-based Automated Vision Impairment Gaze-tracking Analysis Systems
NCT07338513Age-Related Macular Degeneration, Wet Age-related Macular Degeneration
Tan Tock Seng Hospital
Observational
30
Singapore
2026-01
Recruiting
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
NCT07221357Untreated, Unresectable, or Metastatic Colorectal Cancer
DrugsFolfiri·Pumitamig·Folfox·Bevacizumab
Bristol-Myers Squibb
Phase 2/3
990
Singapore
2025-12-31
Recruiting
Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors
NCT07288359Advanced HR+/HER2- Breast Cancer, Advanced CCNE1-amplified Solid Tumors, Metastatic Castration-resistant Prostate Cancer
DrugsLetrozole·Fulvestrant
Novartis Pharmaceuticals
Phase 1/2
205
Singapore
2025-12-29
Recruiting
Evaluate the Feasibility and Effectiveness of a Community-based Care Bundle in Managing and Preventing Pressure Injuries
NCT07074743Pressure Injuries, Caregiver, Community Dwelling Older Adult
Singapore General Hospital
Not applicable
216
Singapore
2025-12-26
Recruiting
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
NCT07174336Breast Neoplasms, Neoplasm Metastasis
DrugsTersolisib·Exemestane·Anastrozole·Ribociclib
Eli Lilly and Company
Phase 3
800
Singapore
2025-12-22
Active, closed
A Study to Assess Zipalertinib Versus Placebo in Participants With Early Stage NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection
NCT07128199Lung Cancer, Adjuvant, Post-surgical, EGFR
DrugZipalertinib
Taiho Oncology, Inc.
Phase 3
360
Singapore
2025-12-22
Recruiting
Role of GLP1 RA Dulaglutide on Severe Intracranial Atherosclerosis
NCT07282041Intracranial Atherosclerosis, Stroke, Ischemic
DrugDulaglutide
National University of Singapore
Phase 2/3
130
Singapore
2025-12-17
Recruiting
Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations
NCT07185997Non-Small-Cell Lung Cancer, Metastatic Non-Small-Cell Lung Cancer, Advanced Non-Small-Cell Lung Cancer, EGFR P-Loop and Alpha C-Helix Compressing
DrugFurmonertinib
ArriVent BioPharma, Inc.
Phase 3
480
Singapore
2025-12-17
Recruiting
ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
NCT07007559Breast Cancer, Metastatic
DrugsEvorpacept·Eribulin·Herceptin·Vinorelbine
ALX Oncology Inc.
Phase 2
120
Singapore
2025-12-10
Recruiting
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEYยฎ Kids)
NCT07107945Chronic Kidney Disease
DrugDapagliflozin
Boehringer Ingelheim
Phase 3
120
Singapore
2025-12-09
Recruiting
Blood Eosinophil Guided Versus Usual Care In The Management Of Mild To Moderate Asthma at Primary Care (BEAM)
NCT07486401Asthma Exacerbations, Biomarkers / Blood, Eosinophil Blood Count
National Healthcare Group Polyclinics
Not applicable
240
Singapore
2025-12-03
Recruiting
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
NCT07276724Severe Asthma
DrugGB-0895
Generate Biomedicines
Phase 3
786
Singapore
2025-12-03
Recruiting
Comparison of Myopic Small Incision Lenticule Extraction (SMILE) With VISUMAX 500 Versus VISUMAX 800 Platforms
NCT07505264Myopia
Singapore Eye Research Institute
Not applicable
100
Singapore
2025-12-01
Recruiting
Antenatal Myo-inositol Supplementation in Pre-existing Diabetes
NCT07241221Perinatal and Neonatal Outcomes in Pregnancies With Type 2 Diabetes Mellitus (T2DM)
National University Hospital, Singapore
Not applicable
182
Singapore
2025-12
Recruiting
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naรฏve Metastatic Castration-resistant Prostate Cancer
NCT07213674Metastatic Castration-resistant Prostate Cancer
DrugsXaluritamig·Cabazitaxel·Abiraterone acetate·Docetaxel
Amgen
Phase 3
750
Singapore
2025-11-28
Recruiting
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
NCT07166094Endometrial Cancer, Recurrent or Progressive Endometrial Cancer
DrugRina-S
Genmab
Phase 3
660
Singapore
2025-11-28
Recruiting
Dupilumab Therapy in Nephrotic Syndrome in Children
NCT07091175Nephrotic Syndrome in Children, Nephrotic Syndrome Steroid-Dependent
DrugDupilumab
National University Hospital, Singapore
Phase 2
66
Singapore
2025-11-27
Recruiting
A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)
NCT07227402Renal Cell Carcinoma
DrugsZanzalintinib·Belzutifan·Cabozantinib
Merck Sharp & Dohme LLC
Phase 3
904
Singapore
2025-11-26
Recruiting
Improving LDL-C Levels Through Temporal Self-regulation Theory-based, Personality-tailored Health Messages
NCT07415109Adherence, Preventive Health Services
National University Health System, Singapore
Not applicable
3,000
Singapore
2025-11-25
Recruiting
Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation
NCT07211958Acute Myeloid Leukemias
DrugRevumenib
Syndax Pharmaceuticals
Phase 3
468
Singapore
2025-11-25
Recruiting
Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors
NCT07261631Pancreatic Ductal Adenocarcinoma, Non-Small Cell Lung Cancer, HR+/HER2- Ductal and Lobular Breast Cancer, Triple Negative Breast Cancer
Drug68Ga-NNS309
Novartis Pharmaceuticals
Phase 1
180
Singapore
2025-11-24
Recruiting
A Platform Study in Non-Small Cell Lung Cancer (NSCLC)
NCT06996782Advanced or Metastatic Non-small Cell Lung Cancer
DrugsRamucirumab·Rilvegostomig·Nab-paclitaxel·Pemetrexed
AstraZeneca
Phase 1/2
152
2025-11-24
Recruiting
Interventional Study of Infigratinib in Children < 3 Years Old With Achondroplasia (ACH)
NCT07169279Achondroplasia
QED Therapeutics, a BridgeBio company
Phase 2
77
Singapore
2025-11-19
Active, closed
A Study of LY4167586 in Participants With Obesity or Overweight Who Are Otherwise Healthy
NCT07225556Overweight, Obesity
Eli Lilly and Company
Phase 1
84
Singapore
2025-11-18
Recruiting
Glaucoma Screening Using Artificial Intelligence Assisted Clinical Model in Singapore's Diabetic Eye Screening Program
NCT07243665Glaucoma
Singapore Eye Research Institute
Not applicable
1,040
Singapore
2025-11-17
By invitation
Trial to Evaluate the Impact of Various Behavioural Interventions to Increase Mammography Uptake Among Singaporean Women
NCT07283107This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women
National University Hospital, Singapore
Not applicable
8,910
Singapore
2025-11-17
Recruiting
Mepitel Film Breast
NCT07729423Breast Cancer, Radiation Dermatitis
National University Hospital, Singapore
Observational
60
Singapore
2025-11-12
Active, closed
Study Comparing Eye Growth Over Time in Children Using Two Myopia Control Lenses
NCT07253064Myopia
Essilor International
Not applicable
20
Singapore
2025-11-11
Active, closed
Phase 2a Study to Assess the Efficacy,Safety and Tolerability of GIA632 in Adult Participants With Moderate to Severe Atopic Dermatitis
NCT07220577Atopic Dermatitis
DrugGIA632
Novartis Pharmaceuticals
Phase 2
34
Singapore
2025-11-10
Recruiting
Histotripsy for Ablation of Liver Tumours in Asia
NCT07428356Liver Malignant Tumors
National Cancer Centre, Singapore
Not applicable
40
Singapore
2025-11-07
Recruiting
DAREON ยฎ -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy
NCT07472517Small Cell Lung Cancer (SCLC), Extensive-stage Small Cell Lung Cancer (ES-SCLC)
DrugsObrixtamig·Etoposide·Atezolizumab·Carboplatin
Boehringer Ingelheim
Phase 3
670
Singapore
2025-11-07
Recruiting
Improving Vaccine Protection for Adults
NCT07527247Immune System Responses and Trained Immunity After AS01 Administration, Healthy Adult
Singapore General Hospital
Phase 2
40
Singapore
2025-11-06
Recruiting
Comparing Tear Proteomics Profile in Dry Eye Disease pre-and Post-treatment With Low Level Light Therapy
NCT07329712Dry Eye, Meibomian Gland Dysfunction (Disorder)
Singapore National Eye Centre
Observational
30
Singapore
2025-11-05
Recruiting
Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)
NCT07100080Non-Small Cell Lung Cancer
DrugsIza-bren·Pemetrexed·Cisplatin·Carboplatin
Bristol-Myers Squibb
Phase 2/3
500
Singapore
2025-11-05
Recruiting
Intermittent Negative Pressure for Patients With Diabetic Foot Ulcers (INPRESS) Study
NCT07291817Diabetic Foot Ulcer
Lo Zhiwen Joseph
Not applicable
30
Singapore
2025-11-03
Recruiting
Cognitive Rehabilitation Using Neurofeedback With Brain-computer Interface
NCT07828496Acquired Brain Injury Including Stroke, Epilepsy
KK Women's and Children's Hospital
Not applicable
70
Singapore
2025-11-01
Not yet open
Anthropometric Outcomes of a Mobile Health Intervention for Eating Behaviour and Lifestyle in Infancy
NCT06457750Childhood Obesity Prevention
KK Women's and Children's Hospital
Not applicable
440
Singapore
2025-11-01
Recruiting
A Pilot Study to Examine the Efficacy of Internet-Delivered Skills Training in Affective and Interpersonal Regulation (i-STAIR) for Individuals With Adverse Childhood Experiences and Subsyndromal Depression
NCT07118072Subthreshold Depression
Institute of Mental Health, Singapore
Not applicable
150
Singapore
2025-10-31
Recruiting
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
NCT07173751Breast Neoplasms
DrugsEribulin·Pumitamig·Gemcitabine·Carboplatin
BioNTech SE
Phase 3
558
Singapore
2025-10-30
Recruiting
Efficacy of Interactive Audio-based Mindfulness ChatGPT-Powered Intervention on Well-being
NCT07333365Perceived Stress, Positive and Negative Affect, State Anxiety, Self Control
Singapore Management University
Not applicable
210
Singapore
2025-10-30
Recruiting
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
NCT07217067Atrial Fibrillation
Novartis Pharmaceuticals
Phase 2
165
Singapore
2025-10-28
Recruiting
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
NCT06793215Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
DrugsDivarasib·Pemetrexed·Cisplatin·Carboplatin
Hoffmann-La Roche
Phase 3
600
Singapore
2025-10-24
Active, closed
A Study Comparing Navlimetostat (BMS-986504) in Combination With Nab-paclitaxel and Gemcitabine Versus Placebo in Combination With Nab-paclitaxel and Gemcitabine in Participants With Untreated Metastatic Pancreatic Ductal Adenocarcinoma With Homozygous MTAP Deletion (MountainTAP-30)
NCT07076121Pancreatic Ductal Adenocarcinoma
DrugsNavlimetostat·Abraxane·Nab-paclitaxel·Gemcitabine
Bristol-Myers Squibb
Phase 2/3
470
Singapore
2025-10-23
Recruiting
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
NCT07213804Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms, Neoplasm Metastasis
DrugsSofe-M·MIRV·Pegylated liposomal doxorubicin·Topotecan
Eli Lilly and Company
Phase 3
1,630
Singapore
2025-10-22
Recruiting
Predicting Risk of Progression of Early to Late AMD in the Aging Eye Through Imaging and Multimodal Evaluation
NCT07653269Age Related Macular Degeneration
Singapore National Eye Centre
Observational
1,500
Singapore
2025-10-18
Recruiting
Continuous Glucose Monitoring (CGM) in Prediabetes
NCT07371546Pre-diabetes
SingHealth Polyclinics
Not applicable
76
Singapore
2025-10-16
Recruiting
Pilot Study of Normative Range of Field of Binocular Single Vision in Adults in Singapore
NCT07257341Binocular Visual Function
Tan Tock Seng Hospital
Observational
30
Singapore
2025-10-15
Recruiting
An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)
NCT07206056Progressive Metastatic Castrate Resistant Prostate Cancer
DrugLuxdegalutamide
Novartis Pharmaceuticals
Phase 1/2
188
Singapore
2025-10-15
Recruiting
Patient Outcomes Following Kinematic and Functional Alignment in Robotic-Assisted Total Knee Arthroplasty With Randomized Insert Types
NCT07533188Knee Osteoarthritis, Degenerative Joint Disease of the Knee
Singapore General Hospital
Not applicable
240
Singapore
2025-10-14
Recruiting
A Study of PRL3-zumab in Neovascular Age-related Macular Degeneration (nAMD)
NCT07547228Neovascular Age Related Macular Degeneration
DrugPRL3-ZUMAB
Intra-IMMUSG Pte Ltd
Phase 1/2
15
Singapore
2025-10-11
Recruiting
Web-based Advance Care Planning Intervention for Patients With Kidney Failure on Dialysis: Pilot Testing of 'My Voice'
NCT07309367Kidney Failure, Chronic Therapy; Hemodialysis
Duke-NUS Graduate Medical School
Not applicable
100
Singapore
2025-10-02
By invitation
Engaging Home-monitored Assessment to Navigate Clinical Decision-making
NCT07399912Hypertension,Essential
SingHealth Polyclinics
Not applicable
116
Singapore
2025-10-01
Recruiting
SINGapore SoniCracker IntraVascular Lithotripsy (SING IVL) Study
NCT07259239Cardiovascular Diseases
National Heart Centre Singapore
Not applicable
40
Singapore
2025-09-30
Recruiting
Audio-Recorded Messages Delivered Via iPad to Prevent Delirium in Hip Fracture Patients
NCT07396532Delirium - Postoperative, Delirium and Post-operative Cognitive Dysfunction (POCD), Delirium, Postoperative
Sengkang General Hospital
Not applicable
30
Singapore
2025-09-29
Recruiting
PRecision gerOMedicinE: Tailored Healthy agEing With Lifestyle, sUpplements and drugS (PROMETHEUS)
NCT07451496Ageing
National University of Singapore
Not applicable
20
Singapore
2025-09-29
Recruiting
Sodium-rich COndiments Unifying Health and Taste
NCT07397754Elevated Blood Pressure, Vascular Health, Sensory Evaluation
Singapore Institute of Food and Biotechnology Innovation
Not applicable
32
Singapore
2025-09-22
Recruiting
A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged โ‰ฅ40 to โ‰ค85 Years With Chronic Obstructive Pulmonary Disease.
NCT07053423Chronic Obstructive Pulmonary Disease
DrugDupilumab
Sanofi
Phase 4
218
Singapore
2025-09-22
Recruiting
Exploratory Study on a Multi-nutrient Supplement and Exercise Program for Improving Health Markers Associated to Longevity in Pre-frail Adults
NCT07454616Pre-Frailty, Aging
National University of Singapore
Not applicable
40
Singapore
2025-09-22
Recruiting
tSCS + UL Robotics Training in SCI Patients
NCT07432321Spinal Cord Injuries
National University Hospital, Singapore
Not applicable
6
Singapore
2025-09-18
Recruiting
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
NCT07190222Chronic Obstructive Pulmonary Disease
DrugLunsekimig
Sanofi
Phase 3
942
Singapore
2025-09-17
Recruiting
A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP
NCT07091630Chronic Inflammatory Demyelinating Polyneuropathy, CIDP, Chronic Inflammatory Demyelinating Polyradiculoneuropathy
DrugEmpasiprubart
argenx
Phase 3
160
Singapore
2025-09-16
Not yet open
WhatsApp Intervention for Seniors' Digital and Cognitive Management (WISDOM)
NCT07161674Cognition, Aged, Digital Health Literacy
National University of Singapore
Not applicable
140
Singapore
2025-09-15
By invitation
Implementation Research on the LILAC Method to Educate Management of Elevated Lipoprotein(a).
NCT07177612Lipoprotein(a), Lipoprotein(a), Hyper-Lp(a)-Emia
Changi General Hospital
Observational
20,000
Singapore
2025-09-09
Recruiting
Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma
NCT07011719Metastatic Clear Cell Renal Cell Carcinoma, Advanced Clear Cell Renal Cell Carcinoma
DrugsCasdatifan·Cabozantinib
Arcus Biosciences, Inc.
Phase 3
720
Singapore
2025-09-08
Recruiting
Altered Non-Visual Photoreception in Patients With Glaucoma: Impacts on Sleep, Alertness, Mood, and Cognition
NCT07364929Glaucoma
National University of Singapore
Not applicable
120
Singapore
2025-09-05
Recruiting
A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
NCT06973187Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
DrugsTacabrutideg·Pirtobrutinib
BeOne Medicines
Phase 3
500
Singapore
2025-09-04
Recruiting
Preventing Diabetes: Impact of an EMR-Based Intervention for Enhanced Pre-Diabetes Management in Primary Care
NCT07252700Pre Diabetes, Diabetes (DM)
Lynette Goh
Not applicable
6,000
Singapore
2025-09-02
Recruiting
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
NCT07157774Elevated Lp(a), Atherosclerotic Cardiovascular Disease (ASCVD)
Eli Lilly and Company
Phase 3
10,450
Singapore
2025-09-02
Recruiting
Use of Anodal tDCS to Enhance Upper Limb Recovery in Stroke
NCT07151729Stroke
Tan Tock Seng Hospital
Not applicable
50
Singapore
2025-09-01
Recruiting
Navigating Advanced Illness Goals And Treatment With Digital Engagement (NAVIGATE)
NCT07134881Paliative Care, Advance Care Planning, Digital Education Interventions, Values, Social
National University of Singapore
Not applicable
200
Singapore
2025-08-27
Recruiting
A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors
NCT07169734Cervical Squamous Cell Carcinoma, Squamous Non-small-cell Lung Cancer, Colorectal Cancer, Intrahepatic Cholangiocarcinoma
Alentis Therapeutics AG
Phase 1/2
180
Singapore
2025-08-26
Recruiting
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
NCT06982521PIK3CA Mutation, HER2- Negative Breast Cancer, Hormone Receptor Positive Tumor, Breast Cancer
DrugsCapivasertib·Fulvestrant
Relay Therapeutics, Inc.
Phase 3
540
Singapore
2025-08-26
Active, closed
Acceptability and Feasibility of PSC Model of Serious Illness Communication
NCT07428655Advanced Breast Cancer
National Cancer Centre, Singapore
Not applicable
28
Singapore
2025-08-25
Recruiting
An International Observational Study of Adults With Acute Infection
NCT07069400Infectious Disease
University of Minnesota
Observational
1,500
Singapore
2025-08-25
Recruiting
A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP
NCT06920004Chronic Inflammatory Demyelinating Polyneuropathy, CIDP, CIDP - Chronic Inflammatory Demyelinating Polyneuropathy
DrugsEmpasiprubart·IVIG
argenx
Phase 3
218
Singapore
2025-08-22
Recruiting
Adjunctive Doxycycline for Central Nervous System Tuberculosis
NCT06446245Tuberculosis, Meningeal, Tuberculosis; Meningitis (Etiology), Tuberculosis, Central Nervous System, Tuberculosis; Meningoencephalitis (Etiology)
DrugDoxycycline
National University Hospital, Singapore
Phase 2
200
Singapore
2025-08-21
Recruiting
A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)
NCT07058077Heterozygous Familial Hypercholesterolemia (HeFH)
DrugsEnlicitide Decanoate·Enlicitide
Merck Sharp & Dohme LLC
Phase 2/3
153
Singapore
2025-08-21
Recruiting
Care Coach-led Integrated Palliative Surgical Oncology and Rehabilitation Care Model for Advanced Cancer Patients
NCT07133269Advanced Cancer
Singapore General Hospital
Not applicable
770
Singapore
2025-08-20
Recruiting
Heart Rate Variability and Music Listening
NCT06929208Heart Rate Variability, Anxiety, Depression
KK Women's and Children's Hospital
Not applicable
120
Singapore
2025-08-19
Active, closed
Demographics and Clinical Characteristics of Ocular Inflammatory Diseases in Singapore
NCT07176130Uveitis, Scleritis and Episcleritis, Endophthalmitis, Masquerade Syndromes
Singapore National Eye Centre
Observational
200
Singapore
2025-08-19
By invitation
Leveraging Large Language Models (LLM) to Enhance Research Competency Among Undergraduate Nursing Students: A Novel Approach to Research Education
NCT07540078Education, AI (Artificial Intelligence)
National University Health System, Singapore
Not applicable
640
Singapore
2025-08-13
Recruiting
Benzydamine Hydrochloride and Post-operative Sore Throat
NCT06676748Sore Throat, Postoperative Care
KK Women's and Children's Hospital
Phase EARLY_PHASE1
106
Singapore
2025-08-11
Recruiting
A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
NCT06979596Malignant Neoplasm
DrugsOpevesostat·Tamoxifen·Exemestane·Letrozole
Merck Sharp & Dohme LLC
Phase 2
250
Singapore
2025-08-11
Recruiting
A Pilot Return-to-Work Cognitive Intervention After Stroke
NCT07116187Stroke
National University of Singapore
Not applicable
100
Singapore
2025-08-08
Recruiting
A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)
NCT07098338Non-Small Cell Lung Cancer
DrugsRamucirumab·Rilvegostomig·Dato-DXd
AstraZeneca
Phase 2
278
Singapore
2025-08-07
Recruiting
A Study to Assess Adverse Events, Change in Disease Activity of Intravenous Telisotuzumab Adizutecan in Combination With Osimertinib as First-Line Treatment in Adult Participants With Locally Advanced Unresectable or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer
NCT07005102Non-Squamous Non-Small Cell Lung Cancer
DrugsTelisotuzumab Adizutecan·Osimertinib·Pemetrexed·Cisplatin
AbbVie
Phase 2/3
854
Singapore
2025-08-03
Recruiting
Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)
NCT07044336Endometrial Cancer, Malignant Solid Tumour
DrugsAdriamycin·Taxol·Doxorubicin·Paclitaxel
AstraZeneca
Phase 3
800
Singapore
2025-08-01
Recruiting
DCB vs. DES in Bifurcation Coronary Lesions
NCT06551662Coronary Artery Disease, DCB
Fondazione Ricerca e Innovazione Cardiovascolare ETS
Not applicable
321
Singapore
2025-08-01
Not yet open
Use of Pyrvinium to Reverse Stomach Precancerous Conditions
NCT06782048STOMACH NEOPLASM
National University Hospital, Singapore
Phase 2
50
Singapore
2025-08
Not yet open
AI-Powered CURAแต€แดน Application for Identifying At-Risk Pregnancies in Obstetric Management
NCT06974188High-risk Pregnancy, Pregnancy, Antenatal Health
National University Hospital, Singapore
Not applicable
1,700
Singapore
2025-08
Not yet open
Developing A Gout Action Plan in Primary Care Setting in Singapore
NCT07061587Gout; Hyperuricemia, Gout Flare, Gout Chronic
SingHealth Polyclinics
Not applicable
72
Singapore
2025-08
Recruiting
Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)
NCT06780111Esophageal Squamous Cell Carcinoma
DrugsIfinatamab Deruxtecan·Sacituzumab tirumotecan·Leucovorin·Adrucil
Merck Sharp & Dohme LLC
Phase 1/2
298
Singapore
2025-07-30
Active, closed
A Phase 1 Study of ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K Mutations
NCT07038369Advanced Solid Tumors, Breast Cancer, Breast Carcinoma, Breast Neoplasms
DrugATV-1601
Atavistik Bio, Inc
Phase 1
134
Singapore
2025-07-29
Active, closed
Feasibility and Outcomes of 3D-printed External Cranial Orthosis After Craniectomy
NCT07122752Traumatic Brain Injury, Acquired Brain Injury, Brain Tumor, Stroke
Tan Tock Seng Hospital
Observational
32
Singapore
2025-07-29
Recruiting
Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity
NCT07037433Atherosclerotic Cardiovascular Disease, Overweight, Obesity
DrugMaridebart cafraglutide
Amgen
Phase 3
12,800
Singapore
2025-07-25
Recruiting
Colchicine for Primary Prevention of Cardiovascular Disease in Adults With Type 2 Diabetes
NCT07837934Type 2 Diabetes Mellitus (T2DM), Atherosclerosis, Cardiovascular Diseases
DrugColchicine
Tan Tock Seng Hospital
Phase 2
300
Singapore
2025-07-24
Recruiting
Left Bundle Branch Area Pacing (LBBAP) PMCF Study
NCT07217392Bradycardia, Right Ventricular Pacing, Heart Failure, Atrial Fibrillation (AF)
Abbott Medical Devices
Not applicable
200
Singapore
2025-07-24
Recruiting
A Study of LY4088044 in Healthy Participants
NCT07090785Healthy
Eli Lilly and Company
Phase 1
104
Singapore
2025-07-24
Recruiting
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
NCT07064759Neovascular Age-Related Macular Degeneration (nAMD)
DrugsEYLEA (aflibercept)·4D-150 IVT
4D Molecular Therapeutics
Phase 3
480
Singapore
2025-07-22
Recruiting
Influence of Rodenstock Spectacle Lenses on Myopia Progression.
NCT06816446Myopia
Rodenstock GmbH
Not applicable
185
Singapore
2025-07-22
Recruiting
EASi-PROTKTโ„ข - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473Diabetes Mellitus, Type 2, Hypertension, Cardiovascular Diseases
DrugsVicadrostat·Dapagliflozin
Boehringer Ingelheim
Phase 3
11,800
Singapore
2025-07-22
Recruiting
Evaluation of Combinational Use of Negative Pressure Wound Therapy (NPWT) for Diabetic Foot Wounds
NCT06832787Diabetic Foot Ulcer
Singapore General Hospital
Not applicable
75
Singapore
2025-07-22
Recruiting
Using Social Influencers for Public Health Education on Antibiotic Use and Antimicrobial Resistance
NCT06998576Community Members
Tan Tock Seng Hospital
Not applicable
3,300
Singapore
2025-07-21
Recruiting
Identification of Molecular Signals in Vitreous Humor Associated With Suboptimal Response to Vascular Endothelial Growth Factor (VEGF) Inhibition in Neovascular Age-related Macular Degeneration (nAMD) Within a Clinical Trial Setting
NCT07249216Age Related Macular Degeneration
DrugsRanibizumab·Faricimab
Singapore National Eye Centre
Not applicable
117
Singapore
2025-07-18
Active, closed
P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk
NCT06468033Primary Myelofibrosis, Myeloproliferative Neoplasm
DrugBesremi
PharmaEssentia
Phase 3
160
Singapore
2025-07-18
Recruiting
Choroidal Venous Congestion Following Scleral Buckling - An Imaging Study
NCT07260097Pachychoroid Disease
Singapore National Eye Centre
Observational
50
Singapore
2025-07-17
Recruiting
Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC
NCT06765109Non-small Cell Lung Cancer, Anaplastic Lymphoma Kinase-positive
DrugsNeladalkib·Alectinib
Nuvalent Inc.
Phase 3
450
Singapore
2025-07-17
Recruiting
Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries
NCT07242742Extremely Deep Caries, Pulpitis
National University Hospital, Singapore
Not applicable
93
Singapore
2025-07-16
Recruiting
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
NCT07033494Early Alzheimer's Disease
Merck Sharp & Dohme LLC
Phase 2
340
Singapore
2025-07-16
Recruiting
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
NCT06997497Colon Adenocarcinoma, Rectal Adenocarcinoma
DrugsBevacizumab biosimilar·Calderasib·Mvasi·Erbitux
Merck Sharp & Dohme LLC
Phase 3
477
Singapore
2025-07-16
Recruiting
A Study of Mezagitamab in Adults With Kidney Condition Called IgA Nephropathy
NCT06963827Kidney Disease
DrugMezagitamab
Takeda
Phase 3
347
Singapore
2025-07-15
Recruiting
Exercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore
NCT07116161Fatigue, Breast Cancer Female
National Cancer Centre, Singapore
Not applicable
100
Singapore
2025-07-14
Active, closed
An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
NCT06991556Metastatic Hormone-sensitive Prostate Cancer
DrugsLuxdegalutamide·Abiraterone·Enzalutamide
Novartis Pharmaceuticals
Phase 2
168
Singapore
2025-07-07
Active, closed
A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)
NCT07047118Prostatic Cancer, Castration-Resistant
DrugsLuxdegalutamide·Lu-PSMA
Novartis Pharmaceuticals
Phase 2
138
Singapore
2025-07-03
Recruiting
A Pilot Study to Evaluate Equol and Its Effects on Menopausal Symptoms Experienced by Women in Singapore
NCT07136220Menopause
Ang Seng Bin
Observational
300
Singapore
2025-07-02
Recruiting
Precision Stratification for Frailty and Cognitive Decline
NCT07081282Frailty, Cognitive Decline
National University of Singapore
Not applicable
252
Singapore
2025-07-01
Recruiting
Project SIRT6 Activator
NCT07500649Aging
National University of Singapore
Not applicable
60
Singapore
2025-07-01
Recruiting
Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
NCT06855277Prostate Cancer
DrugsAAA817·ARPI
Novartis Pharmaceuticals
Phase 3
940
Singapore
2025-07-01
Not yet open
Comparing Effectiveness of Steroids and Methotrexate in Treatment of Chronic Inflammatory Breast Disease
NCT06943482Idiopathic Granulomatous Mastitis
DrugsFolic Acid·Omeprazole·Prednisolone·Methotrexate
National University Hospital, Singapore
Phase 4
40
Singapore
2025-07-01
Active, closed
Using Gout Buddy to Enhance Gout Management
NCT07004231Gout
SingHealth Polyclinics
Not applicable
110
Singapore
2025-07-01
Not yet open
Pioneering Advancements in Cardiocerebrovascular Interactions in the Asia pacFIC - Patent Foramen Ovale Study
NCT06983795Ischemic Stroke, Patent Foramen Ovale
DrugsDipyridamole·Cilostazol·Ticagrelor·Clopidogrel
National University Hospital, Singapore
Observational
1,000
Singapore
2025-07
Active, closed
Safety Of Nrtis for Alzheimer's Therapeutic Advancement in Singapore Study
NCT07210528Mild Cognitive Impairment (MCI), Alzheimer Dementia (AD)
DrugsTAF/FTC·Descovy·Emtricitabine
National University Hospital, Singapore
Phase 1
48
Singapore
2025-06-30
Recruiting
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
NCT06966700Breast Neoplasms, Triple Negative Breast Neoplasms, HR Low-Positive/HER2-Negative Breast Neoplasms
DrugsEpirubicin·Adriamycin·Xeloda·Paraplatin
Merck Sharp & Dohme LLC
Phase 3
2,400
Singapore
2025-06-30
Recruiting
SAS 1: Develop Ocular Disease (OSD) Diagnostic, Algorithms, and Management Protocols for Cataract Surgery
NCT07323264Dry Eye
Louis Tong
Observational
110
Singapore
2025-06-27
Recruiting
Clinical Investigation of a Novel Spectacle Lens on Slowing Down Juvenile Myopia Progression
NCT06850168Myopia
Essilor International
Not applicable
35
Singapore
2025-06-26
Active, closed
A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease
NCT07048197Rheumatoid Arthritis (RA) and Sjรถgren's Disease (SjD)
DrugRapcabtagene autoleucel
Novartis Pharmaceuticals
Phase 1/2
27
Singapore
2025-06-20
Recruiting
An Artificial Intelligence-powered Approach to Precision Immunotherapy of Human Arthritis
NCT07013110Rheumatoid Arthritis (RA), Rheumatology
Prof Salvatore Albani
Phase 2
124
Singapore
2025-06-18
Recruiting
AVIGA3 (Cohort 2.0)
NCT07255859Maculopathy
Tan Tock Seng Hospital
Not applicable
60
Singapore
2025-06-16
Recruiting
Study on the Effect of Atorvastatin Co-administered With Omeprazole on Statin Lactone
NCT06690164Metabolite
DrugsOmeprazole·Atorvastatin
National University Hospital, Singapore
Phase 4
78
Singapore
2025-06-12
Active, closed
A Study to Evaluate V181 Dengue Vaccine in Healthy Participants 2 to 17 Years of Age (V181-005/MOBILIZE-1)
NCT07013487Healthy
Merck Sharp & Dohme LLC
Phase 3
12,000
Singapore
2025-06-11
Active, closed
REVEAL: A Phase 3 Study of Obudanersen (ION582) in Angelman Syndrome
NCT06914609Angelman Syndrome
DrugObudanersen
Ionis Pharmaceuticals, Inc.
Phase 3
156
Singapore
2025-06-10
Recruiting
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
NCT06340568Endometrial Cancer
DrugsDoxorubicin·Docetaxel·Paclitaxel
BioNTech SE
Phase 3
480
Singapore
2025-06-10
Active, closed
Study to Evaluate Tulisokibart for Hidradenitis Suppurativa (MK-7240-012)
NCT06956235Hidradenitis Suppurativa
DrugTulisokibart
Merck Sharp & Dohme LLC
Phase 2
149
Singapore
2025-06-09
Recruiting
The AIRTIVITYโ„ข Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis
NCT06872892Bronchiectasis
DrugVerducatib
Boehringer Ingelheim
Phase 3
1,755
Singapore
2025-06-09
Not yet open
Highly Aspherical Lenslet (HAL) and Binocular Vision (BV) Disorders [HALT X(T) Study]
NCT06863675Myopia, Strabismus
Singapore National Eye Centre
Phase 3
40
Singapore
2025-06-01
Not yet open
Programmable Smart Watch for Remote Pre-habilitation/Rehabilitation Monitoring
NCT06970717Rehabilitation Exercise
Changi General Hospital
Not applicable
20
Singapore
2025-06-01
Not yet open
Be Right! Back: An Artificial Intelligence Enabled Mobile Application for Patients With Low Back Pain
NCT06973915Low Back Pain
Singapore General Hospital
Observational
120
Singapore
2025-06-01
Not yet open
Assessing the Feasibility of the Patient-Reported Outcomes Based Model for Community Care of Patients With Axial Spondyloarthritis Via a Type 1 Pilot Hybrid Effectiveness-Implementation Trial Using the RE-AIM Framework
NCT06968247Axial Spondyloarthritis
Singapore General Hospital
Not applicable
70
Singapore
2025-06
Not yet open
The Effect of Combined Transcranial Pulse Current Stimulation (tPCS) and Transcutaneous Electrical Nerve Stimulation (TENS) on Lower Limb Motor Function in Subacute to Chronic Stroke Patients With Hemiplegia (COMPENSATOR-Stroke)
NCT06999876Stroke Patients With Hemiplegia or Hemiparesis in the Subacute Stage
National University Health System, Singapore
Not applicable
90
Singapore
2025-05-31
Recruiting
Investigating the Prevalence and Risk Factors for Sarcopenia Amongst Adults Seeking Treatment for Obesity
NCT07541677Obesity
Singapore General Hospital
Observational
300
Singapore
2025-05-26
Recruiting
Feasibility, Acceptability and Preliminary Efficacy of the New Iteration of the Innovative Smartphone-based Care Solution for Women With Breast Cancer Undergoing Chemotherapy (iCareBreast+): A Pilot Study Research Proposal
NCT06977360Breast Cancer
National Cancer Centre, Singapore
Not applicable
40
Singapore
2025-05-23
Active, closed
VITUS Post-Market Registry
NCT06832631Peripheral Arterial Disease, Peripheral Arterial Occlusive Disease
OrbusNeich
Observational
283
Singapore
2025-05-22
Recruiting
A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)
NCT06952504Endometrial Cancer
DrugsSacituzumab tirumotecan·Docetaxel·Keytruda·Paclitaxel
Merck Sharp & Dohme LLC
Phase 3
1,123
Singapore
2025-05-22
Active, closed
Metabolite Changes Following Consumption Of Different Protein Drinks In Singapore Older Adults
NCT06956131Aging, Protein Metabolism
National University of Singapore
Not applicable
32
Singapore
2025-05-20
Recruiting
Transperineal Ultrasound as a Biofeedback Tool for Pelvic Floor Muscle Therapy in Postpartum Patients
NCT07065708Pelvic Floor Muscle Training, Transperineal Ultrasound, Biofeedback Therapy, Postpartum
Singapore General Hospital
Not applicable
94
Singapore
2025-05-20
Recruiting
Folinic Acid as a Treatment for Autism Spectrum Disorder in Children
NCT07630506Autism Spectrum Disorder
DrugFolinic acid
KK Women's and Children's Hospital
Phase 2
184
Singapore
2025-05-19
Recruiting
Phase III Extension Study of Efficacy and Safety of Ianalumab With or Without Study Treatment Withdrawal in Participants With Lupus Nephritis (SIRIUS-LN Extension)
NCT06711887Lupus Nephritis
DrugIanalumab
Novartis Pharmaceuticals
Phase 3
348
Singapore
2025-05-19
By invitation
Evaluating the Feasibility and Acceptability of Inhalation Aromatherapy for Patients Undergoing Autologous Haematopoietic Stem Cell Transplant (HSCT)
NCT07209501Chemotherapy-Induced Nausea and Vomiting (CINV)
Singapore General Hospital
Not applicable
30
Singapore
2025-05-15
Active, closed
A Study to Test Whether Treatment With BI 770371 in Combination With Pembrolizumab With or Without Cetuximab Helps People With Head and Neck Cancer Compared With Pembrolizumab Alone
NCT06806852Head and Neck Squamous Cell Carcinoma
DrugsBI 770371·Cetuximab·Pembrolizumab
Boehringer Ingelheim
Phase 1
91
Singapore
2025-05-14
Recruiting
A Study of Transcatheter Aortic Valve Replacement Case Selection and Valve Sizing Using the ABC Bicuspid Sizing Algorithm
NCT06991517Aortic Stenosis
World Health Research Inc.
Observational
290
Singapore
2025-05-13
Recruiting
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
NCT06925737Prostate Cancer, Prostatic Neoplasms
DrugsIfinatamab Deruxtecan·Prednisolone·Prednisone·Docetaxel
Merck Sharp & Dohme LLC
Phase 3
1,440
Singapore
2025-05-13
Recruiting
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
NCT06563895Amyloidosis, Amyloid Cardiomyopathy, Transthyretin Amyloidosis, Cardiomyopathies
DrugAcoramidis
Eidos Therapeutics, a BridgeBio company
Phase 3
587
Singapore
2025-05-12
Active, closed
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-031/LIGHTRAY EXTENSION)
NCT06925750Pulmonary Arterial Hypertension
DrugSotatercept
Merck Sharp & Dohme LLC
Phase 2
130
Singapore
2025-05-12
Recruiting
Evaluating the Effectiveness and Implementation of Caregiver Support Initiatives for Caregivers of Older Patients in Singapore
NCT07090837Caregiver, Caregiver Stress, Caregiver Resilience and Stress
Tan Tock Seng Hospital
Not applicable
400
Singapore
2025-05-08
By invitation
ADL+2.0: Intervention for Prevention of Cognitive Decline in Community-dwelling Older Adults
NCT07141160Cognitive Decline
Tan Tock Seng Hospital
Not applicable
255
Singapore
2025-05-08
Recruiting
Dose-response Effect of Community Dance Programme
NCT07081191Dance, Older Adults, Frailty at Older Adults, Active Ageing
National University of Singapore
Not applicable
284
Singapore
2025-05-07
Recruiting
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
NCT06881784NSCLC (Non-small Cell Lung Cancer), Non-Small Cell Lung Cancer, NSCLC, NSCLC (Non-small Cell Lung Carcinoma)
DrugsCetuximab·Docetaxel
Revolution Medicines, Inc.
Phase 3
590
Singapore
2025-05-06
Recruiting
Effect of Tele-exercise on Cardiorespiratory Fitness in Paediatrics
NCT06770660Cardiorespiratory Fitness, Insulin Resistance
KK Women's and Children's Hospital
Not applicable
122
Singapore
2025-05-02
Recruiting
OneSTOP (One-Stop Telehealth Obesity Program) for Multidisciplinary Weight Management and Related Comorbidities
NCT06890169Obesity and Type 2 Diabetes, NAFLD - Non-Alcoholic Fatty Liver Disease, Hypertension, Dyslipidaemia
Changi General Hospital
Not applicable
120
Singapore
2025-05-01
Recruiting
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)
NCT06884618Neoplasms
Hoffmann-La Roche
Phase 1
405
Singapore
2025-04-30
Recruiting
Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis
NCT06880770Severe Hypertriglyceridemia
DrugPlozasiran
Arrowhead Pharmaceuticals
Phase 3
288
Singapore
2025-04-24
By invitation
An Interventional Study of Infigratinib in Children With Hypochondroplasia
NCT06873035Hypochondroplasia
DrugInfigratinib
QED Therapeutics, a BridgeBio company
Phase 2/3
24
Singapore
2025-04-22
Recruiting
Optimising TREATment for Severe Gram-Negative Bacterial Infections
NCT07004049Bloodstream Infection, Ventilator Associated Bacterial Pneumonia, Hospital Acquired Bacterial Pneumonia, Carbapenem Resistant Bacterial Infection
DrugsCeftolozane-tazobactam·Cefiderocol·Fosfomycin·Meropenem-Vaborbactam
National University of Singapore
Phase 4
600
Singapore
2025-04-21
Recruiting
Sacituzumab Govitecan in Metastatic Salivary Gland and Thyroid Cancers (SG-SGTC)
NCT06923826Salivary Gland Cancer, Thyroid Cancer
DrugSacituzumab Govitecan
National University Hospital, Singapore
Phase 2
32
Singapore
2025-04-15
Recruiting
EXtubation Related Complications - the EXTUBE Study (EXTUBE)
NCT06442930Extubation
University Health Network, Toronto
Observational
3,000
Singapore
2025-04-14
Recruiting
Neoadjuvant ADG126 and Pembrolizumab in Locally Advanced Colorectal Cancer
NCT06846268Locally Advanced Colorectal Cancer
DrugsADG126·Keytruda·Pembrolizumab
National University Hospital, Singapore
Phase 2
20
Singapore
2025-04-14
Active, closed
ASCEND CSP IDE Study
NCT06830746Heart Failure, Ventricular Arrythmia
Abbott Medical Devices
Not applicable
414
Singapore
2025-04-11
Recruiting
Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors
NCT06726148Advanced HR+/HER2- Breast Cancer, Advanced CCNE1-amplified Solid Tumors, Extensive-stage Small Cell Lung Cancer
DrugsRibociclib·Fulvestrant
Novartis Pharmaceuticals
Phase 1/2
280
Singapore
2025-04-03
Recruiting
Implementation of Decade of Healthy Ageing Action Plan to Screen and Prevent Decline in Intrinsic Capacity in Elders (SPICE) Through Multisectoral Collaboration in Singapore
NCT07525583Frailty, Intrinsic Capacity, Lifestyle
National University Hospital, Singapore
Observational
2,500
Singapore
2025-04-01
Recruiting
Discharge Recommendations for Older Adults Using Physical Outcome Measure
NCT06903832Discharge Planning, Older Adults (65 Years and Older), Acute Hospitalization, OUTCOME MEASURES
National University Hospital, Singapore
Observational
60
Singapore
2025-04-01
Recruiting
Digital Positive Affect Intervention Study
NCT06978257Mild to Moderate Anxiety and Depression
National University of Singapore
Not applicable
2,400
Singapore
2025-04-01
Recruiting
Connecting Caregivers With Community Services: The Care Buddy Platform
NCT06817876Dementia
Duke-NUS Graduate Medical School
Not applicable
210
Singapore
2025-04-01
Recruiting
Cervical Lymphatico-Venous Bypass for Treatment of Alzheimer's Disease - Proof of Concept Study (CLyVeB-AD-1 Study)
NCT06965062Alzheimer Disease, Dementia Alzheimer Type, Dementia Alzheimer&#39;s Type, Alzheimer&#39;s Disease
Vincent Tay Khwee Soon
Not applicable
10
Singapore
2025-04-01
Active, closed
A Study to Identify an Optimal Dose of QCZ484 in Mild to Moderate Hypertensive Patients
NCT06857955Hypertension
DrugQCZ484
Novartis Pharmaceuticals
Phase 2
396
Singapore
2025-03-26
Recruiting
Redirecting Poor Sleep Drivers of Early Cardiovascular Disease
NCT06949722Sleep, Cardiovascular Risk Factors
National University of Singapore
Observational
1,500
Singapore
2025-03-24
Recruiting
Proof-of-Concept Study of ACT001 in Adult Patients With Recurrent Glioblastoma Harbouring STAT3-High Signature
NCT06894225Recurrent Glioblastoma
DrugACT001
National Neuroscience Institute
Phase 2
12
Singapore
2025-03-22
Recruiting
A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors
NCT06914128MTAP-deleted Solid Tumors
Bayer
Phase 1/2
450
Singapore
2025-03-21
Recruiting
Impact of IIT-SIT on Dengue Clusters
NCT06894901Dengue
National Environment Agency, Singapore
Not applicable
900
Singapore
2025-03-20
Recruiting
Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)
NCT06819007Ovarian Cancer
DrugsTrastuzumab deruxtecan·Bevacizumab
Daiichi Sankyo
Phase 3
582
Singapore
2025-03-19
Active, closed
cOncomitant Left Atrial aPpendage Closure and Pulsed Field ablaTION-Asia
NCT06686485Concomitant Procedures, Atrial Fibrillation, PFA, LAAC
Boston Scientific Corporation
Observational
433
Singapore
2025-03-18
Active, closed
Exploratory Study on the Effectiveness of Myopia Control Lenses in Slowing Myopia Progression in Young Children
NCT06857864Myopia
Essilor International
Not applicable
25
Singapore
2025-03-17
Recruiting
The Asia-Pacific Mitral & Tricuspid Valve-in-Valve/Valve-in-Ring Registry (AP ViV Registry)
NCT07058935Valve Disease, Heart
National Heart Centre Singapore
Observational
150
Singapore
2025-03-17
Active, closed
A Study to Determine the Efficacy, Safety, and Durability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration
NCT06795048Neovascular Age-related Macular Degeneration (nAMD)
DrugsVabysmo·Faricimab
Hoffmann-La Roche
Phase 4
274
Singapore
2025-03-14
Active, closed
Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA
NCT06868290ANCA Associated Vasculitis (AAV)
DrugRapcabtagene autoleucel
Novartis Pharmaceuticals
Phase 2
126
Singapore
2025-03-13
Recruiting
A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)
NCT06615479Relapsed or Refractory Multiple Myeloma (RRMM)
DrugsArlo-cel·Carfilzomib·Pomalidomide·Daratumumab
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Phase 3
440
Singapore
2025-03-12
Recruiting
Progression Patterns of Choroidal Venous Alterations
NCT07236671Pachychoroid Disease
Singapore National Eye Centre
Observational
250
Singapore
2025-03-04
Recruiting
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723Chronic Kidney Disease and Hypertension
DrugBaxdrostat/dapagliflozin
AstraZeneca
Phase 3
5,000
Singapore
2025-03-03
Recruiting
The Effects of Ripasudil in Patients With FED Undergoing Femtosecond Laser Assisted Cataract Surgery
NCT06048380Fuchs' Endothelial Dystrophy, Cataract
DrugRipasudil
Singapore Eye Research Institute
Phase 3
120
Singapore
2025-03-01
Recruiting
Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
NCT06780670Prostate Cancer
DrugAAA817
Novartis Pharmaceuticals
Phase 2/3
443
Singapore
2025-02-27
Recruiting
Feasibility Study of Single-session Solution Focused Consultation to Enhance Treatment Engagement
NCT07116655Treatment Engagement
Nanyang Technological University
Not applicable
60
Singapore
2025-02-26
Recruiting
Stronger Families Through Art Therapy: A Mixed Methods Programme Evaluation Study
NCT06732297Vulnerable Families
Nanyang Technological University
Not applicable
96
Singapore
2025-02-22
Recruiting
Surviving the Pediatric Intensive Care Unit (PICU)
NCT06812130Post Intensive Care Syndrome (PICS)
KK Women's and Children's Hospital
Observational
404
Singapore
2025-02-11
Recruiting
Asian-Mediterranean Diet and Women's Health
NCT06825936Cardiometabolic Risk Factors, Cardiometabolic Conditions, Women Health
Global Centre for Asian Women's Health
Not applicable
300
Singapore
2025-02-10
By invitation
Pilot Observational Study and Safety Analysis of FL Nourish Capsules in Cancer Patients in Remission
NCT06807515Cancer, Cancer Survivor
Thong Chai Institute of Medical Research
Observational
24
Singapore
2025-02-10
Recruiting
Endoscopic Conversion of Sleeve Gastrectomy to Single Anastomosis Sleeve-ileal Bypass (SASI) for Gastroesophageal Reflux (GERD), Primary and Secondary Non-responder.
NCT06757296Metabolic Syndrome, Severe Obesity, Reflux, Gastroesophageal, Bariatric Surgery
Singapore Health Services
Not applicable
500
Singapore
2025-02-03
Active, closed
Associations Between Dietary Intake and Cardiometabolic and Gut Microbiota Outcomes
NCT06775132Cardiometabolic Risk Factors, Skin Condition, Cognitive Ability, General, Sleep Quality
National University of Singapore
Observational
240
Singapore
2025-02-03
Active, closed
Utility of a Mindfulness App for Outpatients Awaiting Appointments for Mental Health Interventions
NCT07778680Depression Anxiety Disorder, Anxiety and Depression
Institute of Mental Health, Singapore
Not applicable
122
Singapore
2025-02-01
Recruiting
FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC
NCT06788990Metastatic Head and Neck Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma
DrugsFicerafusp alfa·Keytruda·Pembrolizumab
Bicara Therapeutics
Phase 2/3
650
Novena, Singapore
2025-01-28
Recruiting
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
NCT06717347Diffuse Large B-Cell Lymphoma
DrugsRituximab Biosimilar·Zilovertamab vedotin·Riabni·Ruxience
Merck Sharp & Dohme LLC
Phase 3
1,046
Singapore
2025-01-27
Active, closed
Improving Weight Loss in Healthy Adults With Overweight and Obesity: An Artificial Intelligence-assisted Dietary Prediction and Prevention System With Continuous Glucose Monitoring
NCT07395466Overweight , Obesity, Overweight or Obese Adults, Obesity, Overweight and/or Obesity
National University Health System, Singapore
Not applicable
300
Singapore
2025-01-22
Recruiting
Safety of Discontinuing NSBBs in Cirrhotic Patients With Managed Primary Aetiological Factors
NCT06549673Portal Hypertension, Cirrhosis, Varices, Esophageal
Chinese University of Hong Kong
Observational
375
Singapore
2025-01-20
Recruiting
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
NCT06568939Non-Small Cell Lung Cancer
DrugTelisotuzumab vedotin
AbbVie
Phase 2
150
Singapore
2025-01-20
Recruiting
Does High-intensity Exercise Lead to Better Functional Outcomes Early After Stroke in an Inpatient Rehabilitation Setting?
NCT06913127Stroke
Mah Shi Min
Not applicable
36
Singapore
2025-01-20
Recruiting
Intramuscular ACM-CpG Monotherapy in Patients With Advanced/Metastatic Solid Tumors With Prior Response to Immunotherapy Alone or in Combination With Chemotherapy
NCT06587295Advanced Solid Tumor, Metastatic Solid Tumor
DrugExpansion
National Cancer Centre, Singapore
Phase 1
40
Singapore
2025-01-15
Recruiting
A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations
NCT06706076NSCLC (Advanced Non-small Cell Lung Cancer)
BlossomHill Therapeutics
Phase 1/2
675
Kent Ridge, Singapore
2025-01-09
Not yet open
Evaluation of Performance of MiYOSMART Photochromic and Clear Spectacle Lenses in Myopic Children
NCT06717035Myopia, Myopia Progression
Singapore National Eye Centre
Not applicable
202
Singapore
2025-01-02
Recruiting
Rapid Optimisation of Performance Enhancement and Skill (ROPES)
NCT06754007Sedentary Lifestyle
Singapore General Hospital
Not applicable
60
Singapore
2025-01-02
Recruiting
Targeting Osteosarcopaenia and Multimorbidity for Frailty Prevention
NCT06073106Stroke, Traumatic Brain Injury, Knee Osteoarthritis, Breast Cancer
Tan Tock Seng Hospital
Observational
500
Singapore
2025-01-01
Recruiting
Peer Enriched Environment for Recovery (PEER)
NCT07463014Stroke
Nanyang Technological University
Not applicable
20
Singapore
2025-01-01
Recruiting
Brightline: Advancing Mental Health on Campus
NCT06770075Depression, Anxiety, Stress, Positive Affect
Nanyang Technological University
Observational
500
Singapore
2025-01
Not yet open
Breast Cancer Rehabilitation Needs and Service Uptake
NCT06753357Breast Cancer, Cancer Survivorship, Health Attitude
Changi General Hospital
Observational
376
Singapore
2025-01
Recruiting
Treatment Response in Immune-mediated Myositis Associated Rapidly-progressing Interstitial Lung Disease
NCT07775235Interstitial Lung Disease, Myositis
DrugsTofacitinib·Tacrolimus·Prednisolone·Rituximab
Singapore General Hospital
Observational
80
Singapore
2024-12-26
Active, closed
A Phase 2 Study of Anvumetostat in Participants With MTAP-deleted Advanced NSCLC (MTAPESTRY 201)
NCT06593522MTAP-deleted NSCLC
DrugAnvumetostat
Amgen
Phase 2
61
Singapore
2024-12-26
Active, closed
A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma
NCT06679985Hepatocellular Carcinoma
DrugsToripalimab·Bevacizumab
Coherus Oncology, Inc.
Phase 2
72
Singapore
2024-12-20
Active, closed
Phase 2 Study of Rapcabtagene Autoleucel in Myositis
NCT06665256Idiopathic Inflammatory Myopathies
DrugRapcabtagene autoleucel
Novartis Pharmaceuticals
Phase 2
21
Singapore
2024-12-17
Recruiting
A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors
NCT06747585Squamous Non-small-cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Cervical Squamous Cell Carcinoma, Esophageal Squamous Cell Carcinoma
Alentis Therapeutics AG
Phase 1/2
170
Singapore
2024-12-16
Recruiting
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis.
NCT05421858Candidemia, Candidiasis, Invasive
DrugsCaspofungin·Fosmanogepix·Fluconazole
Basilea Pharmaceutica
Phase 3
450
Singapore
2024-12-11
Recruiting
ETC-159 In Combination With Pembrolizumab In Advanced MSS/pMMR Ovarian Cancers
NCT06513624With MSS/pMMR Advanced, Platinum-resistant Ovarian Cancer
DrugPembrolizumab
National University Hospital, Singapore
Phase 1
16
Singapore
2024-12-09
Active, closed
Phase 3 Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Participants With Progressive Metastatic Castration-Resistant Prostate Cancer (XALute)
NCT06691984Metastatic Castration-resistant Prostate Cancer
DrugsXaluritamig·Cabazitaxel·Abiraterone·Enzalutamide
Amgen
Phase 3
707
Singapore
2024-12-09
Recruiting
Body Composition, Frailty, and Function in Rehabilitation
NCT06527742Frailty, Stroke, Debility Due to Disease
Changi General Hospital
Observational
345
Singapore
2024-12-09
Active, closed
Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
NCT06669754Hereditary Angioedema (HAE)
DrugDeucrictibant
Pharvaris Netherlands B.V.
Phase 3
81
Singapore
2024-12-01
Not yet open
Early Screening for Gestational Diabetes Mellitus in a Low Risk Population
NCT06704035Gestational Diabetes Mellitus (GDM), Glucose Intolerance During Pregnancy
National University Hospital, Singapore
Not applicable
120
Singapore
2024-12-01
Recruiting
Mezigdomide and Elranatamab for Relapsed and/or Refractory Multiple Myeloma
NCT06645678Relapsed Refractory Multiple Myeloma (RRMM)
DrugsMezigdomide·Elranatamab·Dexamethasone
YOUNGIL KOH
Phase 1/2
75
Singapore
2024-11-26
Recruiting
A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers
NCT06422403Carcinoma, Hepatocellular, Gastric Adenocarcinoma, GastroEsophageal Cancer, Oesophageal Cancer
National University Hospital, Singapore
Phase 2
360
Singapore
2024-11-25
Recruiting
A Phase 3 Study of NTLA-2001 in ATTRv-PN
NCT06672237Neuromuscular Disease, Neuromuscular Diseases (NMD), Neurodegenerative Disease, Neurodegenerative Disease, Hereditary
DrugNexiguran ziclumeran
Intellia Therapeutics
Phase 3
60
Singapore
2024-11-22
Recruiting
CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.
NCT06690775Epithelial Ovarian Cancer, Primary Peritoneal, Fallopian Tube Cancer, Endometrioid Ovarian Cancer
DrugsTORL-1-23·Pegfilgrastim
TORL Biotherapeutics, LLC
Phase 2
230
Singapore
2024-11-20
Active, closed
Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML
NCT06578247Leukemia
DrugQuizartinib
Daiichi Sankyo
Phase 3
700
Singapore
2024-11-19
Recruiting
Allogeneic NKG2DL-targeting CAR ฮณฮด T Cells (CTM-N2D) in Advanced Cancers (ANGELICA)
NCT05302037Cancer, Malignancy, Refractory Cancer, Relapsed Cancer
CytoMed Therapeutics Pte Ltd
Phase 1
12
Singapore
2024-11-19
Recruiting
A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors
NCT06619587Solid Tumor
Genentech, Inc.
Phase 1
410
Singapore
2024-11-14
Recruiting
Transcutaneous Spinal Cord Stimulation With Robotic Gait Training in Chronic SCI
NCT05921175Spinal Cord Injury
National University Hospital, Singapore
Not applicable
6
Singapore
2024-11-13
Recruiting
LIVERAGEโ„ข - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
NCT06632457Metabolic Dysfunction Associated Steatohepatitis
Boehringer Ingelheim
Phase 3
1,590
Singapore
2024-11-12
Active, closed
A Study of Sequential Therapy With Daplusiran/Tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis B (CHB)
NCT06537414Chronic Hepatitis B Virus Infection, Hepatitis B
DrugBepirovirsen
GlaxoSmithKline
Phase 2
283
Singapore
2024-11-11
Recruiting
AI-driven Narrow-band Imaging Score for Disease Assessment and Outcome Prediction in Ulcerative Colitis
NCT06709209Ulcerative Colitis (UC)
University College Cork
Observational
300
Singapore
2024-11-04
Not yet open
Sleep Health, Workplace Stress and Wellbeing in NUS Staff: the NUS1000 Staff Edition Study
NCT06594549Life Experiences
National University of Singapore
Observational
1,000
Singapore
2024-11-01
Recruiting
Telerehabilitation Robotics for Upper Limb Rehabilitation After STroke
NCT06270459Stroke
Tan Tock Seng Hospital
Not applicable
54
Singapore
2024-11-01
Recruiting
Liquid Biopsy-Based Pre-Screening to Streamline LDCT Lung Cancer Screening in High-Risk Individuals
NCT07358715Lung Cancer, Lung Neoplasms, Early Lung Cancer Detection, Cancer Screening
National University Hospital, Singapore
Not applicable
140
Singapore
2024-11-01
Active, closed
A Study of ZW191 in Participants With Solid Tumors
NCT06555744Advanced Solid Tumors
Zymeworks BC Inc.
Phase 1
145
Singapore
2024-10-30
Active, closed
Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis
NCT06655896Scleroderma, Diffuse
DrugsRapcabtagene autoleucel·Rituximab
Novartis Pharmaceuticals
Phase 2
96
Singapore
2024-10-29
Recruiting
Evaluating the Effectiveness of Aromatherapy for Alleviating Distress in Breast Cancer Patients Before Radiotherapy.
NCT06766058Breast Cancer
National Cancer Centre, Singapore
Not applicable
300
Singapore
2024-10-22
Recruiting
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
NCT06623422Carcinoma, Non-Small-Cell Lung
DrugsIntismeran autogene·Paraplatin·Taxol·Pemetrexed
Merck Sharp & Dohme LLC
Phase 3
680
Singapore
2024-10-21
Recruiting
Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN)
NCT06631339Myopia, Light; Therapy, Complications, Myopia Progression, Short-Sighted
National University of Singapore
Not applicable
396
Singapore
2024-10-21
Recruiting
Hyperpolarized MR Imaging with Carbon-13 Pyruvate in the Human Body
NCT06645691Heart Failure, Cardiometabolic Syndrome, Cancer Diagnosis, Cardiovascular Diseases
DrugHyperpolarized 13C-Pyruvate
National Heart Centre Singapore
Phase 2
200
Singapore
2024-10-17
Recruiting
LIVERAGEโ„ข: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
NCT06632444Metabolic Dysfunction Associated Steatohepatitis (MASH), Liver Fibrosis
Boehringer Ingelheim
Phase 3
1,800
Singapore
2024-10-14
Recruiting
A Novel Home-based Non-invasive Neuromodulation Therapy for Children and Adolescents With Cerebral Palsy
NCT06921538Cerebral Palsy (CP)
KK Women's and Children's Hospital
Not applicable
60
Singapore
2024-10-11
Recruiting
Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations
NCT06581432Solid Tumours
DrugZongertinib
Boehringer Ingelheim
Phase 2
588
Singapore
2024-10-11
Recruiting
Electro-Acupuncture for Obese Patients With Insulin Resistance
NCT06609200Obesity, Insulin Resistance
Nanyang Technological University
Not applicable
60
Singapore
2024-10-10
Recruiting
A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer
NCT06417814Metastatic Non-small Cell Lung Cancer
DrugsTagrisso·Dato-DXd·Osimertinib·Pemetrexed
AstraZeneca
Phase 3
744
Singapore
2024-10-04
Active, closed
Evidence-based Lifestyle Interventions for the Delay of Cognitive Decline Among Older Singaporeans
NCT06661486Non Demented
National University of Singapore
Not applicable
120
Singapore
2024-10-01
Recruiting
Potential of Interface Care Models to Deliver More Appropriate Care to Patients With Acute Medical Illness
NCT07536035Falls Injury, Falls, Hospitalization in Acute Care, Chronic Obstructive Pulmonary Disease (COPD)
National University Hospital, Singapore
Observational
220
Singapore
2024-09-30
Recruiting
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
NCT06492616Breast Cancer
DrugsElacestrant·Tamoxifen·Exemestane·Anastrozole
Stemline Therapeutics, Inc.
Phase 3
4,220
Singapore
2024-09-27
Recruiting
ChemoRT With and Without Dental Stent for Taste Protection in NPC Patients
NCT06733948Nasopharyngeal Carcinoma
National University Hospital, Singapore
Phase 2
50
Singapore
2024-09-24
Active, closed
A Study Evaluating the Efficacy and Safety of Divarasib Versus Sotorasib or Adagrasib in Participants With Previously Treated KRAS G12C-positive Advanced or Metastatic Non-Small Cell Lung Cancer
NCT06497556Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
DrugsDivarasib·Adagrasib·Sotorasib
Hoffmann-La Roche
Phase 3
338
Singapore
2024-09-23
Recruiting
Daily Intake of Multivitamin & Mineral Supplementation Effects on Biological Age of Relatively Healthy Middle-aged Individuals
NCT06666660Relatively Healthy Volunteers
National University of Singapore
Not applicable
400
Singapore
2024-09-23
Recruiting
Innovating Access to Novel Therapies Through Standardized Prospective Integration of Response Evaluations (IMPACT-INSPIRE)
NCT06956248Solid Tumor
National Cancer Centre, Singapore
Observational
50
Singapore
2024-09-12
Active, closed
A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)
NCT06581198Lupus Erythematosus, Systemic, Lupus Nephritis
DrugRapcabtagene autoleucel
Novartis Pharmaceuticals
Phase 2
179
Singapore
2024-09-04
Recruiting
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
NCT06548542Crohn's Disease
DrugsABBV-8736·Trosunilimab·Lutikizumab·Risankizumab
AbbVie
Phase 2
590
Singapore
2024-09-04
Recruiting
Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
NCT06274801Pulmonary Arterial Hypertension
DrugSeralutinib
Gossamer Bio USA, Inc.
Phase 3
330
Singapore
2024-09-03
Not yet open
The GOS-Frail (Geriatric Oncology Supportive Care for Frail Older Adults With Cancer) Study
NCT06553378Geriatric Oncology, Supportive Care, Quality of Life
Tan Tock Seng Hospital
Not applicable
154
Singapore
2024-09-01
Recruiting
A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
NCT06452277Advanced Non-small Cell Lung Cancer, HER2 Mutation
DrugsSevabertinib·Pemetrexed·Cisplatin·Carboplatin
Bayer
Phase 3
555
Singapore
2024-08-28
Active, closed
Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)
NCT06486441Endometrial Cancer
DrugsAdriamycin·Sacituzumab Govitecan·Taxol·Doxorubicin
Gilead Sciences
Phase 3
640
Singapore
2024-08-28
Active, closed
Singapore SARS-CoV-2 Human Challenge Study
NCT06654973COVID 19
Tan Tock Seng Hospital
Not applicable
20
Singapore
2024-08-27
Active, closed
Assessment of Human Exposure to Chemical Hazards
NCT06526169Dietary Exposure
National University of Singapore
Observational
300
Singapore
2024-08-21
Recruiting
A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis
NCT06461897Atopic Dermatitis
DrugsUpadacitinib·Dupilumab
AbbVie
Phase 3
675
Singapore
2024-08-19
Active, closed
Brown Fat as Therapeutic Strategy for Obesity and Associated Metabolic Diseases Via Functional Food/Nutraceutical Approach - Molecular Mechanisms of Pentacyclic Triterpenes (BRACE)
NCT06484543Diabetes, Brown Adipose Tissue
Institute for Human Development and Potential (IHDP), Singapore
Not applicable
50
Singapore
2024-08-15
Recruiting
Timely Interventions to Enable and Reach Patients With Heart Failure, and Their Caregivers With Palliative Care
NCT06244953Heart Failure
National Cancer Centre, Singapore
Not applicable
240
Singapore
2024-08-14
Active, closed
A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.
NCT06247995Breast Cancer
DrugsGa-NeoB·Lu-NeoB·Capecitabine
Novartis Pharmaceuticals
Phase 1/2
20
Singapore
2024-08-14
Active, closed
A Study of Subcutaneously Injected Epcoritamab Plus Oral Lenalidomide Tablets Compared to Intravenously (IV) Infused Rituximab Plus IV Infused Gemcitabine and IV Infused Oxaliplatin in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
NCT06508658Diffuse Large B-Cell Lymphoma
DrugsEpcoritamab·Lenalidomide·Rituximab·Oxaliplatin
Genmab
Phase 3
379
Singapore
2024-08-13
Recruiting
Scoring Balloon and High Pressure Balloon in the Treatment of Arteriovenous Graft Stenosis
NCT06503692Arteriovenous Graft Stenosis
DK Medical Technology (Suzhou) Co., Ltd.
Not applicable
140
Singapore
2024-08-13
Recruiting
WeArable teChnology daTa driVen digitAl healTh cOachINg (ACTIVATION)- A Mixed-methods Study
NCT06752772Elevated Blood Pressure, Hypertension, Overweight/Obesity, Type 2 Diabetes Mellitus (T2DM)
Alexandra Hospital
Not applicable
1,700
Singapore
2024-08-06
Recruiting
Integrative Neuro-social Cognitive Strategy Programme for Instilling REcovery (INSPIRE) a Community-Based Cognitive Remediation Trial
NCT06286202Schizophrenia, Schizoaffective Disorder
Singapore Institute of Technology
Not applicable
160
Singapore
2024-08-06
Recruiting
Evaluating Different Protocols of Non-invasive Brain Stimulation (NIBS) in Stroke Rehabilitation
NCT07786649Stroke
National University Hospital, Singapore
Not applicable
250
Singapore
2024-08-05
Recruiting
Evaluating the Impact of Different Methods of HPV DNA Testing for Cervical Cancer Screening in Primary Care Settings
NCT06528184Uterine Cervical Neoplasms
National Healthcare Group Polyclinics
Not applicable
650
Singapore
2024-08-05
Active, closed
Open-label Extension Study of Enlicitide Decanoate (MK-0616/Enlicitide Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-019) CORALreef Extension
NCT06492291Hypercholesterolemia
DrugsEnlicitide Decanoate·Enlicitide
Merck Sharp & Dohme LLC
Phase 3
3,000
Singapore
2024-08-05
Recruiting
Enhanced Community First Responder System Evaluation in Singapore
NCT06530433Out-Of-Hospital Cardiac Arrest
Singapore General Hospital
Not applicable
165
Singapore
2024-08-01
Recruiting
Asia Pediatric Intensive Care Epidemiology and Outcomes Study
NCT06481644Pediatrics, Intensive Care Unit, Critical Illness
KK Women's and Children's Hospital
Observational
10,000
Singapore
2024-08-01
Recruiting
The MUSE Study for Menopausal Arthralgia
NCT06530459Arthralgia, Menopause, Perimenopausal Disorder, Joint Pain
National University Hospital, Singapore
Phase 2/3
100
Singapore
2024-08-01
Recruiting
Brain Computer Interface (BCI) Integrated Wearable Hand Robotic Glove System for Upper Limb Stroke Rehabilitation
NCT06076928Stroke
Tan Tock Seng Hospital
Not applicable
60
Singapore
2024-08-01
Recruiting
A Qualitative and Usability Evaluation of Advanced Technologies for Home Upper Limb Neurorehabilitation Post-stroke
NCT06406569Stroke
Tan Tock Seng Hospital
Not applicable
30
Singapore
2024-07-31
Recruiting
LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC
NCT06216301Metastatic Non-small Cell Lung Cancer
DrugPembrolizumab
NovoCure GmbH
Phase 3
734
Singapore
2024-07-31
Active, closed
A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)
NCT06459180Cervical Cancer
DrugsTisotumab Vedotin·Vinorelbine·Topotecan·Sacituzumab tirumotecan
Merck Sharp & Dohme LLC
Phase 3
686
Singapore
2024-07-24
Recruiting
PillSense for Suspected Upper Gastrointestinal Bleeding
NCT06500468Bleeding Ugi
Tan Tock Seng Hospital
Not applicable
84
Singapore
2024-07-18
Recruiting
Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer
NCT06029270Metastatic Nasopharyngeal Carcinoma, Recurrent Nasopharyngeal Carcinoma, Stage IV Nasopharyngeal Carcinoma AJCC v8
DrugsCis-platinum·Relatlimab·CDDP·Paraplatin
National Cancer Institute (NCI)
Phase 2
156
Singapore
2024-07-15
Active, closed
Better Risk Perception Via Patient Similarity to Control Hyperglycemia and Sustained by Telemonitoring
NCT06607497Diabetes Mellitus, Type 2
SingHealth Polyclinics
Not applicable
360
Singapore
2024-07-15
Recruiting
A Study to Evaluate the Safety and Activity of SAR448501/DR-0201 in Patients With Relapsed/ Refractory B-Cell Non-Hodgkin Lymphoma
NCT06392477B-cell Non Hodgkin Lymphoma
DrugSAR448501
Sanofi
Phase 1
96
Singapore
2024-07-08
Recruiting
Tislelizumab and Metronomic Capecitabine as Maintenance in High-risk Locoregionally-advanced Nasopharyngeal Carcinoma
NCT06093061Nasopharyngeal Carcinoma
National Cancer Centre, Singapore
Phase 2
53
Singapore
2024-07-03
Active, closed
Group Drumming for Improving the Health of Community-Dwelling Elderly
NCT06489834Quality of Life, Depression, Sleep, Blood Pressure
KK Women's and Children's Hospital
Not applicable
300
Singapore
2024-07-01
Recruiting
Continuous Glucose Monitoring Glycemic cHAracterization During Pregnancy
NCT06357728Gestational Diabetes, Glucose Metabolism Disorders, Metabolic Disease
KK Women's and Children's Hospital
Not applicable
60
Singapore
2024-07-01
Recruiting
Longitudinal Multimodal Profiling of Balance and Gait In Stroke
NCT06187467Stroke
Tan Tock Seng Hospital
Observational
30
Singapore
2024-07-01
Recruiting
Severe Complications During Ventricular Tachycardia or Premature Ventricular Complex Ablation
NCT07777744Ventricular Tachycardia (VT), Premature Ventricular Complexes
University Hospital, Basel, Switzerland
Observational
15,000
Singapore
2024-07-01
Recruiting
Compliance With Standard Care vs Ready to Eat Meals Prior to Bariatric Surgery
NCT06461247Bariatric Surgery Candidate
National University Hospital, Singapore
Not applicable
140
Singapore
2024-07-01
Recruiting
A Novel Individualized Connectome-guided Approach for Precision Intermittent Theta Burst Stimulation for Depression
NCT06385223Depression
Institute of Mental Health, Singapore
Not applicable
70
Singapore
2024-07-01
Recruiting
Validation of the Use of Terahertz Scanning System on Corneal Scars and Corneal Edema
NCT06983652Corneal Diseases, Corneal Scars and Opacities, Corneal Edema
Singapore Eye Research Institute
Observational
150
Singapore
2024-07-01
Recruiting
Pembrolizumab and Olaparib Treatment for Relapsed or Refractory Peripheral T-Cell Lymphoma
NCT06160843Relapsed Peripheral T-Cell Lymphoma, Refractory Peripheral T-Cell Lymphoma
National Cancer Centre, Singapore
Phase 2
24
Singapore
2024-07-01
Active, closed
A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
NCT06468228Hidradenitis Suppurativa
DrugLutikizumab
AbbVie
Phase 3
1,400
Singapore
2024-06-27
Active, closed
Artificial Intelligence (AI) - Assisted Visual Impairment Screening Model: Community-based Implementation and Evaluation of Performance, Feasibility and Costs.
NCT06877988Visual Impairment
Singapore Eye Research Institute
Not applicable
400
Singapore
2024-06-27
Recruiting
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
NCT06393374Triple-Negative Breast Cancer
DrugsXeloda·Sacituzumab tirumotecan·Keytruda·Capecitabine
Merck Sharp & Dohme LLC
Phase 3
1,530
Singapore
2024-06-24
Recruiting
Towards Optimal Fertility, Fathering and Fatherhood studY
NCT06293235Reproductive Issues, Fertility Issues
KK Women's and Children's Hospital
Observational
960
Singapore
2024-06-21
Active, closed
Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma
NCT06356129Large B-cell Lymphoma
DrugsGolcadomide·Vincristine·Doxorubicin·Prednisone
Celgene
Phase 3
850
Singapore
2024-06-19
Recruiting
Technology-enabled Anticipatory Guidance and Peer Support in Empowering Parents to Prevent Early Childhood Caries
NCT06558955Dental Caries, Dental Caries in Children, Diet Habit
National University of Singapore
Not applicable
600
Singapore
2024-06-15
Recruiting
Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease
NCT05831085Coronary Artery Stenosis
Duk-Woo Park, MD
Not applicable
1,500
Singapore
2024-06-14
Recruiting
Multi-modal Training Program to Promote Physical Activity After Stroke
NCT06409351Stroke, Physical Inactivity
Singapore General Hospital
Not applicable
120
Singapore
2024-06-11
Recruiting
Alpha Ketoglutarate Enhances Geroprotection In Surgery (AEGIS)
NCT07031128CABG
National University Hospital, Singapore
Phase 4
250
Singapore
2024-06-11
Recruiting
Predictors of Vitrectomy Outcomes in Myopic Foveoschisis
NCT07774637Myopic Traction Maculopathy
Singapore National Eye Centre
Not applicable
30
Singapore
2024-06-10
Recruiting
Prospective Clinical Assessment Study in Children With Hypochondroplasia
NCT06410976Hypochondroplasia
QED Therapeutics, a BridgeBio company
Observational
150
Singapore
2024-06-05
Recruiting
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
NCT06430801Crohn's Disease
DrugTulisokibart
Merck Sharp & Dohme LLC
Phase 3
1,200
Singapore
2024-06-05
Active, closed
Machine Learning to Predict Factors Affecting Rehabilitation Length of Stay and Healthcare Costs for Neurological Rehabilitation
NCT06704997Stroke, Acquired Brain Injury, Traumatic Brain Injury, Brain Tumor
Tan Tock Seng Hospital
Observational
10,000
Singapore
2024-06-01
Recruiting
An Exploratory Study of a Wearable Robotic Hand Orthosis
NCT06412237Stroke
Tan Tock Seng Hospital
Not applicable
20
Singapore
2024-06-01
Active, closed
A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease
NCT06401044Thyroid Eye Disease
DrugAMG 732
Amgen
Phase 1/2
94
Singapore
2024-05-30
Recruiting
Exploring the Role of Parental Emotion Regulation and Outcomes of Parental Emotional Coaching on Child and Adolescent Psychosocial Outcomes
NCT06588985Emotion Regulation
National University of Singapore
Not applicable
200
Singapore
2024-05-24
Recruiting
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
NCT06419374Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
DrugPegozafermin
89bio, Inc.
Phase 3
762
Singapore
2024-05-24
Recruiting
Integrative Adolescence Research Programme (IARP)
NCT06622681Executive Dysfunction, Physical Stress, Mental Health Wellness 1
Institute for Human Development and Potential (IHDP), Singapore
Observational
1,200
Singapore
2024-05-21
Active, closed
Hyperbaric Bupivacaine Versus Hyperbaric Prilocaine in Spinal Anaesthesia
NCT07329582Knee Replacement, Total, Knee Replacement Surgery
DrugsPrilocaine·Bupivacaine
National University Hospital, Singapore
Phase 4
50
Singapore
2024-05-17
Recruiting
Dietary Intervention on Atopy
NCT06547372Atopic Dermatitis, Atopic, Allergic Diseases, Allergic Rhinitis
National University of Singapore
Not applicable
110
Singapore
2024-05-10
Active, closed
A Follow-up Study to Test Long-term Treatment With Nerandomilast in People With Pulmonary Fibrosis Who Took Part in a Previous Study With Nerandomilast
NCT06238622Idiopathic Pulmonary Fibrosis, Progressive Pulmonary Fibrosis
DrugNerandomilast
Boehringer Ingelheim
Phase 3
1,666
Singapore
2024-05-06
Recruiting
Remote Patient Monitoring Solution for Chronic Respiratory Disease Management
NCT06377345Asthma, Asthma Attack, Asthma in Children, Asthma Acute
SingHealth Polyclinics
Not applicable
180
Singapore
2024-05-01
Recruiting
UNdeRstAnding Novel Variants in AcutE MyocardiaL Infarction in Young Adults
NCT06698341Myocardial Infarction, Acute
National Heart Centre Singapore
Observational
1,200
Singapore
2024-04-29
Recruiting
The PACT (Patient Activation Through Conversations) Study
NCT06444074Diabetes Mellitus, Diabetes Mellitus, Type 2
National Healthcare Group Polyclinics
Not applicable
432
Singapore
2024-04-22
Recruiting
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
NCT06312176Breast Neoplasms
DrugsLiposomal doxorubicin·Abraxane·Xeloda·Sacituzumab tirumotecan
Merck Sharp & Dohme LLC
Phase 3
1,200
Singapore
2024-04-14
Recruiting
An Open-Label, Single Arm Study of the Efficacy of Accelerated Intermittent Theta Burst Stimulation in Schizophrenia Patients With Persistent Negative Symptoms
NCT06351514Schizophrenia; Negative Type
Institute of Mental Health, Singapore
Phase 3
40
Singapore
2024-04-01
Recruiting
Evaluation of the Safety of Terahertz Scanning System on Corneas
NCT06967792Corneal Diseases
Singapore Eye Research Institute
Observational
5
Singapore
2024-04-01
Active, closed
Elevated Lipoprotein(a) in Hospital Staff
NCT06304415Hypercholesterolemia, Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia, Cardiovascular Diseases
Changi General Hospital
Observational
2,800
Singapore
2024-04-01
Recruiting
A Study of VRN110755 in Patients With EGFR-Mutant Non-Small Cell Lung Cancer
NCT07699328EGFR-Mutant Non-Small Cell Lung Cancer
Voronoi, Inc
Phase 1/2
315
Singapore
2024-03-26
Recruiting
Study of EGFR TKI in Patients With Advanced NSCLC Harbouring EGFR Mutations
NCT06062823NSCLC
DrugsGilotrif·Afatinib
National University Hospital, Singapore
Phase 2
35
Singapore
2024-03-25
Recruiting
A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma
NCT06256588Neoplasms, Head and Neck
DrugDostarlimab
GlaxoSmithKline
Phase 3
864
Singapore
2024-03-21
Recruiting
A Single-arm, Open-label Clinical Trial to Evaluate the Effect of SMT04 in Irritable Bowel Syndrome (IBS)
NCT06636513Irritable Bowel Syndrome
Changi General Hospital
Not applicable
40
Singapore
2024-03-20
Active, closed
Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease
NCT06268886Alzheimer Disease, Early Onset
DrugMoponetug
Bristol-Myers Squibb
Phase 2
310
Singapore
2024-03-20
Recruiting
A Pan-Asian Clinical Database of EGFR Exon 20 Insertion Mutated NSCLC
NCT06418412Advanced EGFR Exon 20 Insertion Mutated Non-Small Cell Lung Cancer
National Cancer Centre, Singapore
Observational
600
Singapore
2024-03-15
Recruiting
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
NCT06318169Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis
DrugPegozafermin
89bio, Inc.
Phase 3
1,350
Singapore
2024-03-13
Recruiting
An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.
NCT05939414Oligometastatic Prostate Cancer (OMPC)
DrugsPiflufolastat·Lu-PSMA
Novartis Pharmaceuticals
Phase 3
450
Singapore
2024-03-12
By invitation
Nicotinamide Supplementation in Glaucoma
NCT06731582Glaucoma
Singapore Eye Research Institute
Phase 3
520
Singapore
2024-03-12
Active, closed
Direct Selective Laser Trabeculoplasty in Ethnic Chinese Population
NCT05902871Primary Open Angle Glaucoma, Ocular Hypertension, Normal Tension Glaucoma
BelkinVision
Not applicable
40
Singapore
2024-03-11
Active, closed
Development and Evaluation of 'My Voice': A Randomized Controlled Trial
NCT06090734Advance Care Planning, Heart Failure
Duke-NUS Graduate Medical School
Not applicable
244
Singapore
2024-03-07
Active, closed
Protocol for Inpatient Nursing Frailty Assessment (INFA)
NCT06469723Functional Status, Frailty
Tan Tock Seng Hospital
Not applicable
300
Singapore
2024-03-03
Recruiting
Aspirational Rehabilitation Coaching for Holistic Health (ARCH): A Pilot Pre-Post Experimental Study
NCT06596551Stroke, Psychological Well-Being, Psychosocial Functioning
Nanyang Technological University
Not applicable
60
Singapore
2024-03-01
Recruiting
Redirecting Immune, Lipid and Metabolic Drivers of Early Cardiovascular Disease: The RESET Cohort Study
NCT06211868Cardiovascular Diseases, Metabolic Syndrome, Non-Alcoholic Fatty Liver Disease
National University Hospital, Singapore
Observational
3,000
Singapore
2024-03-01
Recruiting
A Multi-domain and Multi-component Falls Intervention Program for Community- Dwelling Older Adults: SAFE-TECH
NCT06102954Fall Prevention, Fall Injury
Duke-NUS Graduate Medical School
Not applicable
400
Singapore
2024-03-01
Recruiting
App-based Motivational Interviewing and Artificial Intelligence in Diabetes Management
NCT06214520Diabetes Mellitus Type 2
Singapore General Hospital
Not applicable
525
Singapore
2024-02-23
Active, closed
Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)
NCT06117774Limited Stage Small Cell Lung Cancer, Small Cell Lung Cancer
DrugTarlatamab
Amgen
Phase 3
404
Singapore
2024-02-20
Recruiting
A Study to Assess the Efficacy, Safety and Pharmacokinetics of EYU688 in Patients With Dengue Fever
NCT06006559Dengue
Novartis Pharmaceuticals
Phase 2
108
Singapore
2024-02-20
Active, closed
A Trial to Learn How Effective and Safe Odronextamab is Compared to Standard of Care for Adult Participants With Previously Treated Aggressive B-cell Non-Hodgkin Lymphoma
NCT06230224B-Cell Non-Hodgkin Lymphoma (B-NHL)
DrugsOdronextamab·Ifosfamide·Paraplatin·Cytarabine
Regeneron Pharmaceuticals
Phase 3
216
Singapore
2024-02-15
Active, closed
Beamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment
NCT06151574Lung Cancer, Non-squamous, Non-small Cell
DrugsZongertinib·Pemetrexed·Keytruda·Cisplatin
Boehringer Ingelheim
Phase 3
428
Singapore
2024-02-09
Recruiting
Addressing Medication Non-adherence in Patients With Poorly Controlled Hypertension Using Urine Mass Spectrometry
NCT06938633Hypertension, Uncontrolled Hypertension, Non-Adherence, Medication
Changi General Hospital
Not applicable
100
Singapore
2024-02-07
Recruiting
Omission of Axillary Surgery in Breast Cancer Patients
NCT06259513Breast Cancer, Sentinel Lymph Node, Breast Neoplasms
KK Women's and Children's Hospital
Not applicable
350
Singapore
2024-02-06
Recruiting
Study of Olverembatinib (HQP1351) in Patients With CML-CP
NCT06423911Chronic Myeloid Leukemia, CML, CML, Chronic Phase
DrugsBosutinib·Olverembatinib
Ascentage Pharma Group Inc.
Phase 3
333
Singapore
2024-02-05
Recruiting
A Phase Ib/II Study of an Anti-HER3 Antibody, HMBD-001, With Cetuximab +/- Docetaxel in Advanced Squamous Cell Cancers
NCT05910827Advanced or Metastatic Squamous Non-Small Cell Lung Cancer, Advanced Head and Neck Squamous Cell Carcinoma, Advanced Esophageal Squamous Cell Carcinoma, Cervical Squamous Cell Carcinoma
DrugsHMBD-001·Cetuximab·Docetaxel
Hummingbird Bioscience
Phase 1/2
398
Singapore
2024-02-05
Recruiting
Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)
NCT06003387Hemophilia B
CSL Behring
Phase 3
35
Singapore
2024-01-30
Active, closed
Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)
NCT06225596Metastatic Urothelial Cancer
DrugsZelenectide pevedotin·Avelumab·Gemcitabine·Cisplatin
BicycleTx Limited
Phase 2
375
Singapore
2024-01-24
Recruiting
A Three-arm Randomized Phase II Study of Dostarlimab Alone or With Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study)
NCT06023862Ovarian Neoplasms, Endometrial Neoplasms, Uterine Cervical Neoplasms, Vulvar Cancer
DrugsPegylated liposomal doxorubicin·Dostarlimab·Doxorubicin·Gemcitabine
Yonsei University
Phase 2
198
Singapore
2024-01-22
Recruiting
Reducing Delirium After CABG Surgery With Early Activation and Sleep-Promoting Routines
NCT06107517Delirium, Postoperative
National University Hospital, Singapore
Not applicable
300
Singapore
2024-01-08
Recruiting
App-based Diabetes Management and Community-based Interventions
NCT06688903Diabetes Mellitus Type 2
Singapore General Hospital
Not applicable
150
Singapore
2024-01-06
Recruiting
Randomised Clinical Trial Comparing Drug-coated Balloon to Plain Balloon for All Peripheral AVF Stenosis
NCT06553443Arteriovenous Fistula, Arteriovenous Fistula Stenosis, Dialysis Access Malfunction
Singapore General Hospital
Phase 3
94
Singapore
2024-01-04
Active, closed
A Phase II Study of AAA617 Alone and AAA617 in Combination With ARPI in Patients With PSMA PET Scan Positive CRPC
NCT05849298Prostatic Neoplasm
DrugsARPI·Pylarify·Illuccix·Lu-PSMA
Novartis Pharmaceuticals
Phase 2
49
Singapore
2024-01-03
Recruiting
Saline Enema Administration in Meconium Obstruction of Prematurity and Impact on the Resolution, Feeds, Microbiome, and Gut-brain Axis.
NCT06048614Meconium Obstruction of Prematurity
KK Women's and Children's Hospital
Not applicable
95
Singapore
2024-01-02
Recruiting
Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants
NCT06556446Ischemic Stroke
Insel Gruppe AG, University Hospital Bern
Observational
2,800
Singapore
2024-01-01
Not yet open
Outcomes With Treatment and Withdraw of Secukinumab in Patients With Plaque Psoriasis
NCT04239859Plaque Psoriasis
DrugsAcitretin·Cyclosporin A·Secukinumab·Methotrexate
Singapore General Hospital
Phase 4
40
Outram Park
2024-01
Recruiting
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)
NCT06136624Prostate Cancer Metastatic
DrugsFludrocortisone acetate·Opevesostat·Zytiga·Hydrocortisone
Merck Sharp & Dohme LLC
Phase 3
1,310
Singapore
2023-12-31
Active, closed
Pulsed Field Ablation (PFA) vs Anti-Arrhythmic Drug (AAD) Therapy as a First Line Treatment for Persistent Atrial Fibrillation
NCT06096337Persistent Atrial Fibrillation
Boston Scientific Corporation
Not applicable
484
Singapore
2023-12-28
Recruiting
Tissue Sodium Quantification in Patients With Primary Aldosteronism: See Sodium to Treat
NCT06569589Hypertension, Primary Aldosteronism, Hypokalemia
Jens Titze
Observational
80
Singapore
2023-12-27
Recruiting
Evaluation and Implementation Preparation of a Proactive Palliative Care Model (ENABLE-SG)
NCT06044441Neoplasms
National Cancer Centre, Singapore
Not applicable
715
Singapore
2023-12-26
Recruiting
FET PET in Differentiating Tumour Progression From Pseudoprogression in High Grade Glioma
NCT06172595Glioma, Malignant
Singapore General Hospital
Phase 2
22
Singapore
2023-12-21
Recruiting
Observational Study Protocol: LIVER-R
NCT06252753Hepatobiliary Cancers
AstraZeneca
Observational
4,000
Singapore
2023-12-20
Recruiting
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
NCT06136650Metastatic Castration-resistant Prostate Cancer (mCRPC), Prostatic Neoplasms
DrugsFludrocortisone acetate·Opevesostat·Prednisone Acetate·Zytiga
Merck Sharp & Dohme LLC
Phase 3
1,314
Singapore
2023-12-18
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Singaporean investigative site. Derived from ClinicalTrials.gov. Retrieved 1 October 2026. https://priyalifescience.com/clinical-trials-singapore

Query this register directly
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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Singapore and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 948 studies in total at the last sync on 30 Sep 2026, 03:16 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in Singapore?

487 of the 948 studies in this register are recruiting new participants as of the 30 Sep 2026, 03:16 UTC sync. A further 78 have not yet opened recruitment, 363 are active but closed to new participants, and 20 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase, 948 studies
PhaseStudiesRecruitingShare
Not applicable29716731.3%
Phase 32359424.8%
Observational1469015.4%
Phase 21195512.6%
Phase 154255.7%
Phase 1/253335.6%
Phase 2/325132.6%
Phase 41891.9%
Phase EARLY_PHASE1110.1%

Most active sponsors

Lead sponsors with the most studies
Lead sponsorStudiesRecruiting
National University Hospital, Singapore9150
Novartis Pharmaceuticals6018
KK Women's and Children's Hospital5024
National University of Singapore4823
Singapore General Hospital4429
National Cancer Centre, Singapore3623
Merck Sharp & Dohme LLC3220
AstraZeneca2510
Tan Tock Seng Hospital2516
Eli Lilly and Company2311

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Browse trials by condition

Breast Cancer (31) Stroke (20) Non-Small Cell Lung Cancer (16) Myopia (14) Obesity (13) Heart Failure (12) Hepatocellular Carcinoma (12) Coronary Artery Disease (12) Healthy (11) Prostate Cancer (11) Hypertension (10) Cardiovascular Diseases (10) Anxiety (8) Solid Tumors (7) Endometrial Cancer (7)
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Browse trials by site location

Singapore (939)
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.