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Clinical Trials in Singapore / NCT07795372
Starting soon Not applicable

Effect of Co-consuming Different Dietary Protein Sources With Salad on the Bioavailability of Carotenoids

NCT07795372 · tracked via the Priya Life Science Singapore tracker
Phase
Not applicable
Started
2026-09
Last updated
2026-09-02

Condition(s) studied

Postprandial Carotenoid Response

Investigational drug(s) / intervention(s)

Salad onlySalad + ChickenSalad + TunaSalad + EggSalad + Soybean

Salad only: Control group, consumption of only salad

Salad + Chicken: Consumption of salad with chicken

Salad + Tuna: Consumption of salad with tuna

Salad + Egg: Consumption of salad with egg

Salad + Soybean: Consumption of salad with soybean

Study summary

The goal of this clinical trial is to learn if different protein types will affect carotenoid responses in humans when co-consumed with salad. The main questions it aims to answer are:

* What are the effect of dietary protein co-consumption with salad on postprandial carotenoid levels in Singapore adults?
* Do different whole-food protein sources enhance the bioavailability of carotenoids in Singapore adults?

Participants will:

Consume salad with a form of protein (chicken, tuna, egg, soybean) Have their postprandial plasma carotenoid and triglyceride outcomes evaluated

Eligibility

Sex
ALL
Min age
21 Years
Max age
45 Years
Healthy volunteers
Accepted
Inclusion Criteria: 1. English-literate and able to give informed consent 2. Singaporean Adults aged 21 to 45 (inclusive) 3. Body mass index of 18.5 to 23.0 kg/m2 (inclusive) 4. At least 50 kg 5. Healthy (based on screening results) Exclusion Criteria: 1. Currently participating in another clinical study that involves altering regular diet and/or involves consuming a dietary supplement or investigated food product as an intervention 2. High blood pressure (≥ 140/90 mmHg) 3. Underlying health conditions that may affect metabolic functions 4. Consuming carotenoid supplements regularly (i.e., more than three times a week) for the past 3 months, and not willing to discontinue consumption 3 months before and during the study duration 5. Weight change \> 3 kg in the past 3 months 6. Exercising vigorously over the past 3 months (i.e., engaging in high-intensity exercises for more than 3 hours a week, where high-intensity exercises leave one out of breath and unable to talk or sing during the workout) 7. Current smokers or have quit smoking for less than 5 years 8. Drinking \> 2 alcoholic drinks per day (i.e., one drink is defined as either 150 ml of wine, 340 ml of beer/cider or 45 ml of distilled spirit) 9. If drinking ≤ 2 alcoholic drinks per day, not willing to stop consumption of alcoholic beverages two days before and on the day of the test visits 10. Not willing to stop consumption of caffeinated beverages 10 to 12 hours before and on the day of the test visits 11. Currently on a specialised diet (e.g., vegetarian, vegan, weight loss diet) 12. Had serious food allergies in the past, or having intolerance, sensitivities or allergies to any of the following: soy/soy-derived products, eggs, fish and crustaceans, starch/starch-derived products (e.g., rice, corn, wheat, potato), gluten 13. Disease or impairment of the liver 14. Currently diagnosed with diabetes, gastrointestinal issues (e.g., lactose intolerance, irritable bowel syndrome), gout and/or G6PD deficiency 15. Taking antibiotics 2 weeks prior to study participation 16. Taking anti-hypertensive or cholesterol-lowering drugs for less than 3 years unless medically declared by an official doctor to be in stable condition 17. Poor peripheral venous access based on past experiences with blood drawing 18. Individuals with pacemaker or related electrical medical devices 19. Pregnant, lactating, or planning pregnancy in the next 6 months 20. Have donated blood (whole blood or apheresis) or participated in any other clinical study or trial requiring blood draws within the last 3 months 21. Clinical anemia (hemoglobin \<12.0 g/dL in women and \<13.0 g/dL in men)

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
NUS, Department of Food Science and Technology, 1 Science Drive 3, Block S13, #03-07, Singapore, 117542 Singapore Singapore

More National University of Singapore trials in Singapore

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07795372 on ClinicalTrials.gov ↗ ← All trials in Singapore